$259+ Cheap flights from Roanoke to St. Louis (ROA - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/16. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — STL
Aug 21 — Aug 281
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Roanoke to St. Louis
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Best
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One-way
Cheapest flights from Roanoke to St. LouisExplore the most affordable flight options available from Roanoke to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 22, 2026.
Explore the most affordable flight options available from Roanoke to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 22, 2026.
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:50 pm
ROA
- STL
1 stop5h 10m
United Airlines
Mon 8/249:30 am
STL
- ROA
1 stop6h 39m
United Airlines
Deal found 7/20![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:59 pm
ROA
- STL
1 stop4h 59m
Delta
Mon 8/105:23 pm
STL
- ROA
1 stop6h 04m
Delta
Deal found 7/19![Delta logo]()
$324
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:59 pm
ROA
- STL
1 stop4h 59m
Delta
Sat 8/810:31 am
STL
- ROA
1 stop4h 41m
Delta
Deal found 7/19![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:53 pm
ROA
- STL
1 stop5h 05m
American Airlines
Tue 8/45:10 am
STL
- ROA
1 stop4h 30m
American Airlines
Deal found 7/21![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:34 am
ROA
- STL
1 stop4h 56m
United Airlines
Tue 11/38:40 am
STL
- ROA
1 stop4h 18m
United Airlines
Deal found 7/20![United Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:00 am
ROA
- STL
1 stop4h 33m
American Airlines
Mon 8/36:14 am
STL
- ROA
1 stop7h 10m
American Airlines
Deal found 7/21![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/257:53 pm
ROA
- STL
1 stop5h 05m
American Airlines
Mon 7/275:10 am
STL
- ROA
1 stop4h 30m
American Airlines
Deal found 7/20![American Airlines logo]()
$414
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:07 am
ROA
- STL
1 stop4h 30m
American Airlines
Sun 10/255:28 am
STL
- ROA
1 stop4h 01m
American Airlines
Deal found 7/21![American Airlines logo]()
$427
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:53 pm
ROA
- STL
1 stop5h 05m
American Airlines
Sun 7/266:13 pm
STL
- ROA
1 stop4h 46m
American Airlines
Deal found 7/21![American Airlines logo]()
$429
Best flights from Roanoke to St. LouisDiscover carefully curated flight deals from Roanoke to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 22, 2026.
Discover carefully curated flight deals from Roanoke to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 22, 2026.
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:18 am
ROA
- STL
1 stop5h 59m
Delta
Mon 8/2412:52 pm
STL
- ROA
1 stop5h 27m
Delta
Deal found 7/20![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:15 am
ROA
- STL
1 stop4h 17m
American Airlines
Sun 8/97:35 am
STL
- ROA
1 stop3h 50m
American Airlines
Deal found 7/19![American Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:34 am
ROA
- STL
1 stop4h 56m
United Airlines
Tue 11/38:40 am
STL
- ROA
1 stop4h 18m
United Airlines
Deal found 7/19![United Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:53 pm
ROA
- STL
1 stop5h 05m
American Airlines
Tue 8/45:10 am
STL
- ROA
1 stop4h 30m
American Airlines
Deal found 7/21![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:00 am
ROA
- STL
1 stop4h 54m
Delta
Mon 8/105:23 pm
STL
- ROA
1 stop6h 04m
Delta
Deal found 7/19![Delta logo]()
$537
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:59 pm
ROA
- STL
1 stop4h 59m
Delta
Tue 8/115:23 pm
STL
- ROA
1 stop6h 04m
Delta
Deal found 7/19![Delta logo]()
$537
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/511:18 am
ROA
- STL
1 stop4h 15m
Delta
Fri 8/75:23 pm
STL
- ROA
1 stop16h 14m
Delta
Deal found 7/19![Delta logo]()
$540
Last-minute flights from Roanoke to St. LouisDiscover last-minute flight deals from Roanoke to St. Louis. Data last updated July 22, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to St. Louis. Data last updated July 22, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:53 pm
ROA
- STL
1 stop5h 05m
American Airlines
Sun 7/266:13 pm
STL
- ROA
1 stop4h 46m
American Airlines
Deal found 7/21![American Airlines logo]()
$429
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/257:53 pm
ROA
- STL
1 stop5h 05m
American Airlines
Mon 7/275:10 am
STL
- ROA
1 stop4h 30m
American Airlines
Deal found 7/20![American Airlines logo]()
$414
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:00 am
ROA
- STL
1 stop4h 33m
American Airlines
Mon 8/36:14 am
STL
- ROA
1 stop7h 10m
American Airlines
Deal found 7/21![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:53 pm
ROA
- STL
1 stop5h 05m
American Airlines
Tue 8/45:10 am
STL
- ROA
1 stop4h 30m
American Airlines
Deal found 7/21![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:59 pm
ROA
- STL
1 stop4h 59m
Delta
Mon 8/105:23 pm
STL
- ROA
1 stop6h 04m
Delta
Deal found 7/19![Delta logo]()
$324
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:59 pm
ROA
- STL
1 stop4h 59m
Delta
Sat 8/810:31 am
STL
- ROA
1 stop4h 41m
Delta
Deal found 7/19![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:00 am
ROA
- STL
1 stop4h 20m
Delta
Sat 8/85:33 pm
STL
- ROA
1 stop16h 04m
Delta
Deal found 7/19![Delta logo]()
$520
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:59 pm
ROA
- STL
1 stop4h 59m
Delta
Tue 8/115:23 pm
STL
- ROA
1 stop6h 04m
Delta
Deal found 7/19![Delta logo]()
$537
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:50 pm
ROA
- STL
1 stop5h 10m
United Airlines
Mon 8/249:30 am
STL
- ROA
1 stop6h 39m
United Airlines
Deal found 7/20![United Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1910:26 am
ROA
- STL
3 stops26h 36m
United Airlines
Tue 8/258:40 am
STL
- ROA
1 stop4h 38m
United Airlines
Deal found 7/20![United Airlines logo]()
$492
One-way flights from Roanoke to St. LouisSearch for one-way flight options from Roanoke to St. Louis. Find affordable one-way fares based on user searches. Data last updated July 22, 2026.
Search for one-way flight options from Roanoke to St. Louis. Find affordable one-way fares based on user searches. Data last updated July 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/162:46 pm
ROA
- STL
3 stops29h 37m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$259
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/164:20 pm
ROA
- STL
1 stop4h 22m
American Airlines
Deal found 7/19![American Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:50 pm
ROA
- STL
2 stops19h 50m
United Airlines
Deal found 7/20![United Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:05 pm
ROA
- STL
2 stops27h 22m
United Airlines
Deal found 7/18![United Airlines logo]()
$423
Find flight deals from Roanoke to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (American Airlines) |
One-way from | $259 (Kiwi.com) |
Popular in | November |
Cheapest in | February |
Average price | $353 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 22, 2026.
Use the filters below to find and compare flights from Roanoke to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Fri 8/21
11:18 am-4:17 pm
1 stop5h 59m
Lambert-St Louis
Mon 8/24
12:52 pm-7:19 pm
1 stop5h 27m
$309
Quickest round-trip
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Fri 8/7
6:15 am-9:32 am
1 stop4h 17m
Lambert-St Louis
Sun 8/9
7:35 am-12:25 pm
1 stop3h 50m
$324
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Sat 8/1
7:53 pm-11:58 pm
1 stop5h 05m
Lambert-St Louis
Tue 8/4
5:10 am-10:40 am
1 stop4h 30m
$369
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Sat 10/31
10:34 am-2:30 pm
1 stop4h 56m
Lambert-St Louis
Tue 11/3
8:40 am-1:58 pm
1 stop4h 18m
$389
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Mon 8/10
6:00 am-9:54 am
1 stop4h 54m
Lambert-St Louis
Mon 8/10
5:23 pm-12:27 am
1 stop6h 04m
$537
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Sun 8/9
7:59 pm-11:58 pm
1 stop4h 59m
Lambert-St Louis
Tue 8/11
5:23 pm-12:27 am
1 stop6h 04m
$537
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Wed 8/5
11:18 am-2:33 pm
1 stop4h 15m
Lambert-St Louis
Fri 8/7
5:23 pm-10:37 am
1 stop16h 14m
$540
Cheapest one-way
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Sat 8/15
11:18 am-4:17 pm
1 stop5h 59m
$269
Quickest one-way
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Sun 8/16
4:20 pm-7:42 pm
1 stop4h 22m
$269
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Sun 8/16
2:46 pm-11:59 pm
3 stops34h 13m
$272
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Roanoke to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to St. Louis in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Roanoke-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Roanoke-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Roanoke to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Roanoke with our price prediction graph.
ROA-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to St. Louis
What is the cheapest month to book a flight from Roanoke to St. Louis?
Currently, February is the cheapest month in which you can book a flight from Roanoke to St. Louis (average of $269). Flying from Roanoke to St. Louis in November is currently the most expensive (average of $522). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Roanoke to St. Louis?
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated July 22, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Roanoke to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Roanoke to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Farmington
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Roanoke and St. Louis flights
Browse other Roanoke and St. Louis flight options. Last updated on July 22, 2026.
Other flights from Roanoke
Browse through other flights departing from Roanoke. Flights are based on user searches made on Cheapflights and were last updated on July 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 22, 2026.
Top 3 airlines flying from Roanoke to St. Louis
Discover the top 3 airlines that operate flights from Roanoke to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$328 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$353 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$254 | Average$388 | FlexibilityNo cancel fee | On-timeN/A |