$145+ Cheap flights from Roanoke to St. Louis (ROA - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/8. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — STL
Jun 7 — Jun 141
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Roanoke to St. Louis
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Best
Last-minute
One-way
Cheapest flights from Roanoke to St. LouisExplore the most affordable flight options available from Roanoke to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 8, 2026.
Explore the most affordable flight options available from Roanoke to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 8, 2026.
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:50 pm
ROA
- STL
1 stop4h 47m
Delta
Sun 9/205:30 pm
STL
- ROA
1 stop5h 20m
Delta
Deal found 5/4![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:51 pm
ROA
- STL
2 stops7h 25m
American Airlines
Mon 7/69:22 am
STL
- ROA
1 stop6h 54m
American Airlines
Deal found 5/5![American Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:59 pm
ROA
- STL
1 stop4h 57m
Delta
Mon 7/67:12 pm
STL
- ROA
1 stop4h 20m
Delta
Deal found 5/7![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:30 pm
ROA
- STL
1 stop5h 29m
Delta
Tue 6/97:08 am
STL
- ROA
1 stop6h 40m
Delta
Deal found 5/5![Delta logo]()
$324
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:30 pm
ROA
- STL
1 stop5h 29m
Delta
Tue 5/266:57 pm
STL
- ROA
1 stop4h 37m
Delta
Deal found 5/7![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:00 am
ROA
- STL
1 stop4h 33m
American Airlines
Sat 7/115:19 pm
STL
- ROA
1 stop5h 52m
American Airlines
Deal found 5/6![American Airlines logo]()
$343
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:47 pm
ROA
- STL
1 stop4h 35m
United Airlines
Tue 9/15:00 am
STL
- ROA
1 stop7h 35m
United Airlines
Deal found 5/5![United Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:00 am
ROA
- STL
1 stop5h 59m
American Airlines
Mon 5/256:15 am
STL
- ROA
1 stop7h 09m
American Airlines
Deal found 5/3![American Airlines logo]()
$398
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:50 pm
ROA
- STL
1 stop4h 46m
Delta
Tue 5/127:05 am
STL
- ROA
1 stop6h 45m
Delta
Deal found 5/5![Delta logo]()
$414
Best flights from Roanoke to St. LouisDiscover carefully curated flight deals from Roanoke to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 8, 2026.
Discover carefully curated flight deals from Roanoke to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 8, 2026.
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:50 pm
ROA
- STL
1 stop4h 47m
Delta
Sat 9/193:42 pm
STL
- ROA
1 stop7h 08m
Delta
Deal found 5/3![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:04 pm
ROA
- STL
1 stop6h 39m
American Airlines
Wed 5/279:24 am
STL
- ROA
1 stop5h 48m
American Airlines
Deal found 5/8![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:47 pm
ROA
- STL
1 stop4h 35m
United Airlines
Tue 9/15:00 am
STL
- ROA
1 stop7h 35m
United Airlines
Deal found 5/5![United Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:50 pm
ROA
- STL
1 stop4h 47m
Delta
Sun 9/275:30 pm
STL
- ROA
1 stop5h 20m
Delta
Deal found 5/3![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:50 pm
ROA
- STL
1 stop4h 47m
Delta
Sun 9/205:30 pm
STL
- ROA
1 stop5h 20m
Delta
Deal found 5/4![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/111:13 am
ROA
- STL
1 stop4h 39m
Delta
Mon 7/67:12 pm
STL
- ROA
1 stop4h 20m
Delta
Deal found 5/3![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:00 am
ROA
- STL
1 stop4h 43m
Delta
Thu 7/231:22 pm
STL
- ROA
1 stop4h 53m
Delta
Deal found 5/5![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:30 pm
ROA
- STL
1 stop5h 29m
Delta
Tue 5/266:57 pm
STL
- ROA
1 stop4h 37m
Delta
Deal found 5/7![Delta logo]()
$339
Last-minute flights from Roanoke to St. LouisDiscover last-minute flight deals from Roanoke to St. Louis. Data last updated May 8, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to St. Louis. Data last updated May 8, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
ROA
- STL
1 stop4h 44m
Delta
Tue 5/126:57 pm
STL
- ROA
1 stop4h 37m
Delta
Deal found 5/5![Delta logo]()
$414
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
ROA
- STL
1 stop4h 44m
Delta
Mon 5/117:01 pm
STL
- ROA
1 stop4h 33m
Delta
Deal found 5/7![Delta logo]()
$429
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:30 pm
ROA
- STL
1 stop5h 29m
Delta
Tue 6/97:08 am
STL
- ROA
1 stop6h 40m
Delta
Deal found 5/5![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:09 pm
ROA
- STL
1 stop5h 46m
United Airlines
Tue 6/95:29 pm
STL
- ROA
2 stops15h 13m
United Airlines
Deal found 5/4![United Airlines logo]()
$522
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:09 pm
ROA
- STL
1 stop5h 46m
United Airlines
Wed 6/106:00 am
STL
- ROA
2 stops26h 42m
United Airlines
Deal found 5/4![United Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:00 am
ROA
- STL
1 stop5h 59m
American Airlines
Mon 5/256:15 am
STL
- ROA
1 stop7h 09m
American Airlines
Deal found 5/3![American Airlines logo]()
$398
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:30 pm
ROA
- STL
1 stop5h 29m
Delta
Tue 5/266:57 pm
STL
- ROA
1 stop4h 37m
Delta
Deal found 5/7![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/23:30 pm
ROA
- STL
1 stop7h 08m
Delta
Tue 6/97:08 am
STL
- ROA
1 stop6h 40m
Delta
Deal found 5/5![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:15 am
ROA
- STL
2 stops16h 06m
United Airlines
Tue 6/91:13 pm
STL
- ROA
1 stop19h 33m
United Airlines
Deal found 5/5![United Airlines logo]()
$550
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:00 am
ROA
- STL
1 stop4h 32m
American Airlines
Sun 6/145:03 pm
STL
- ROA
1 stop4h 51m
American Airlines
Deal found 5/6![American Airlines logo]()
$479
One-way flights from Roanoke to St. LouisSearch for one-way flight options from Roanoke to St. Louis. Find affordable one-way fares based on user searches. Data last updated May 8, 2026.
Search for one-way flight options from Roanoke to St. Louis. Find affordable one-way fares based on user searches. Data last updated May 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:08 pm
ROA
- STL
2 stops26h 22m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/224:08 pm
ROA
- STL
2 stops41h 44m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/253:48 pm
ROA
- STL
2 stops42h 04m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/54:08 pm
ROA
- STL
2 stops22h 47m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$226
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:00 am
ROA
- STL
1 stop11h 33m
American Airlines
Deal found 5/5![American Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:38 pm
ROA
- STL
2 stops43h 14m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/194:08 pm
ROA
- STL
2 stops27h 45m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$260
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:30 pm
ROA
- STL
1 stop5h 29m
Delta
Deal found 5/5![Delta logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/42:38 pm
ROA
- STL
2 stops43h 17m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$276
Find flight deals from Roanoke to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (Delta) |
One-way from | $145 (Kiwi.com) |
Popular in | April |
Cheapest in | February |
Average price | $412 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 8, 2026.
Use the filters below to find and compare flights from Roanoke to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Fri 9/18
7:50 pm-11:37 pm
1 stop4h 47m
Lambert-St Louis
Sat 9/19
3:42 pm-11:50 pm
1 stop7h 08m
$309
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Fri 9/25
7:50 pm-11:37 pm
1 stop4h 47m
Lambert-St Louis
Sun 9/27
5:30 pm-11:50 pm
1 stop5h 20m
$309
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Fri 9/18
7:50 pm-11:37 pm
1 stop4h 47m
Lambert-St Louis
Sun 9/20
5:30 pm-11:50 pm
1 stop5h 20m
$309
Quickest round-trip
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Wed 7/1
11:13 am-2:52 pm
1 stop4h 39m
Lambert-St Louis
Mon 7/6
7:12 pm-12:32 am
1 stop4h 20m
$309
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Thu 7/9
6:00 am-9:43 am
1 stop4h 43m
Lambert-St Louis
Thu 7/23
1:22 pm-7:15 pm
1 stop4h 53m
$309
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Sat 5/23
6:04 pm-11:43 pm
1 stop6h 39m
Lambert-St Louis
Wed 5/27
9:24 am-4:12 pm
1 stop5h 48m
$339
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Fri 5/22
7:30 pm-11:59 pm
1 stop5h 29m
Lambert-St Louis
Tue 5/26
6:57 pm-12:34 am
1 stop4h 37m
$339
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Sat 8/29
5:47 pm-9:22 pm
1 stop4h 35m
Lambert-St Louis
Tue 9/1
5:00 am-1:35 pm
1 stop7h 35m
$384
Cheapest one-way
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Tue 6/30
6:00 am-4:33 pm
1 stop11h 33m
$242
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Wed 6/10
7:05 am-11:49 am
1 stop5h 44m
$269
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Roanoke to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to St. Louis in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Roanoke-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Roanoke-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Roanoke to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Roanoke with our price prediction graph.
ROA-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to St. Louis
What is the cheapest month to book a flight from Roanoke to St. Louis?
Currently, February is the cheapest month in which you can book a flight from Roanoke to St. Louis (average of $269). Flying from Roanoke to St. Louis in April is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Roanoke to St. Louis?
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated May 8, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Roanoke to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.2
Overall
7.9
Comfort
7.9
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Food
7.2
Overall
7.9
Comfort
7.9
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Food
7.2
Overall
7.9
Comfort
7.9
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Food
7.2
Overall
7.9
Comfort
7.9
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Roanoke to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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St. Louis flight routes
Alternative routes for Roanoke to St. Louis
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Complete your trip
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Search flights from Roanoke to St. Louis by cabin class
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Roanoke and St. Louis flights
Browse other Roanoke and St. Louis flight options. Last updated on May 8, 2026.
Other flights from Roanoke
Browse through other flights departing from Roanoke. Flights are based on user searches made on Cheapflights and were last updated on May 8, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 8, 2026.
Top 3 airlines flying from Roanoke to St. Louis
Discover the top 3 airlines that operate flights from Roanoke to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$328 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$338 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$308 | FlexibilityNo cancel fee | On-timeN/A |