$269+ Cheap flights from Roanoke (ROA) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/7. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — MCI
Aug 5 — Aug 121
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to Missouri with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Roanoke to MissouriExplore the most affordable flight options available from Roanoke to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 6, 2026.
Explore the most affordable flight options available from Roanoke to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 6, 2026.
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:10 am
ROA
- MCI
1 stop5h 36m
American Airlines
Sat 8/16:21 pm
MCI
- ROA
1 stop4h 50m
American Airlines
Deal found 7/2![American Airlines logo]()
$308
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am
ROA
- MCI
1 stop6h 09m
Delta
Sun 11/112:04 pm
MCI
- ROA
1 stop4h 54m
Delta
Deal found 7/2![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:57 pm
ROA
- STL
1 stop4h 56m
Delta
Mon 8/35:23 pm
STL
- ROA
1 stop6h 04m
Delta
Deal found 7/2![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:48 am
ROA
- MCI
1 stop5h 30m
American Airlines
Fri 7/311:26 pm
MCI
- ROA
1 stop5h 37m
American Airlines
Deal found 7/3![American Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:35 pm
ROA
- SGF
1 stop6h 08m
American Airlines
Tue 8/113:01 pm
SGF
- ROA
1 stop5h 09m
American Airlines
Deal found 7/2![American Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/164:48 pm
ROA
- STL
1 stop4h 15m
American Airlines
Mon 7/206:13 pm
STL
- ROA
1 stop4h 46m
American Airlines
Deal found 7/1![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am
ROA
- SGF
2 stops8h 50m
Delta
Sun 11/156:45 pm
SGF
- ROA
1 stop4h 38m
Delta
Deal found 7/4![Delta logo]()
$340
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/94:48 pm
ROA
- STL
1 stop4h 15m
American Airlines
Thu 7/236:13 pm
STL
- ROA
1 stop4h 46m
American Airlines
Deal found 7/2![American Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:00 am
ROA
- SGF
1 stop5h 17m
American Airlines
Wed 8/512:23 pm
SGF
- ROA
1 stop5h 58m
American Airlines
Deal found 7/2![American Airlines logo]()
$356
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:59 pm
ROA
- MCI
1 stop4h 59m
Delta
Sat 7/181:17 pm
MCI
- ROA
1 stop7h 26m
Delta
Deal found 7/3![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2610:26 am
ROA
- MCI
1 stop5h 24m
United Airlines
Sat 8/295:39 pm
MCI
- ROA
1 stop5h 04m
United Airlines
Deal found 7/2![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:00 am
ROA
- STL
1 stop4h 43m
Delta
Thu 7/236:58 pm
STL
- ROA
1 stop4h 27m
Delta
Deal found 7/6![Delta logo]()
$389
Best flights from Roanoke to MissouriDiscover carefully curated flight deals from Roanoke to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 6, 2026.
Discover carefully curated flight deals from Roanoke to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 6, 2026.
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:57 pm
ROA
- STL
1 stop4h 56m
Delta
Mon 8/35:23 pm
STL
- ROA
1 stop6h 04m
Delta
Deal found 7/2![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/27:53 pm
ROA
- STL
1 stop5h 05m
American Airlines
Sat 8/81:54 pm
STL
- ROA
1 stop4h 27m
American Airlines
Deal found 7/5![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2610:26 am
ROA
- MCI
1 stop5h 24m
United Airlines
Sat 8/295:39 pm
MCI
- ROA
1 stop5h 04m
United Airlines
Deal found 7/1![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:02 pm
ROA
- SGF
1 stop5h 17m
Delta
Mon 9/76:58 pm
SGF
- ROA
1 stop4h 29m
Delta
Deal found 7/1![Delta logo]()
$335
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/164:48 pm
ROA
- STL
1 stop4h 15m
American Airlines
Mon 7/206:13 pm
STL
- ROA
1 stop4h 46m
American Airlines
Deal found 7/1![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:00 am
ROA
- SGF
1 stop6h 11m
Delta
Sun 11/156:45 pm
SGF
- ROA
1 stop4h 38m
Delta
Deal found 7/4![Delta logo]()
$335
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:40 am
ROA
- STL
1 stop6h 22m
United Airlines
Sat 9/58:30 am
STL
- ROA
1 stop7h 39m
United Airlines
Deal found 7/5![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:59 pm
ROA
- MCI
1 stop4h 59m
Delta
Sat 7/181:17 pm
MCI
- ROA
1 stop7h 26m
Delta
Deal found 7/4![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:40 am
ROA
- STL
1 stop4h 54m
United Airlines
Sun 7/261:13 pm
STL
- ROA
1 stop6h 50m
United Airlines
Deal found 7/6![United Airlines logo]()
$413
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:35 pm
ROA
- SGF
1 stop6h 08m
American Airlines
Tue 8/1111:27 am
SGF
- ROA
2 stops8h 43m
American Airlines
Deal found 7/2![American Airlines logo]()
$501
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:49 am
ROA
- SGF
1 stop4h 56m
United Airlines
Sat 10/39:00 am
SGF
- ROA
2 stops13h 44m
United Airlines
Deal found 7/1![United Airlines logo]()
$485
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:05 am
ROA
- SGF
2 stops12h 03m
Delta
Sun 7/266:53 pm
SGF
- ROA
1 stop4h 32m
Delta
Deal found 7/2![Delta logo]()
$492
This American Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:00 am
ROA
- SGF
1 stop8h 40m
American Airlines
Sun 7/267:15 am
SGF
- ROA
1 stop15h 03m
American Airlines
Deal found 7/5![American Airlines logo]()
$557
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:20 am
ROA
- SGF
2 stops10h 23m
United Airlines
Sun 11/156:15 pm
SGF
- ROA
2 stops14h 08m
United Airlines
Deal found 7/4![United Airlines logo]()
$538
Last-minute flights from Roanoke to MissouriDiscover last-minute flight deals from Roanoke to Missouri. Data last updated July 6, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Missouri. Data last updated July 6, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/94:48 pm
ROA
- STL
1 stop4h 15m
American Airlines
Thu 7/236:13 pm
STL
- ROA
1 stop4h 46m
American Airlines
Deal found 7/2![American Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:00 am
ROA
- STL
1 stop4h 43m
Delta
Thu 7/236:58 pm
STL
- ROA
1 stop4h 27m
Delta
Deal found 7/6![Delta logo]()
$389
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/102:51 pm
ROA
- STL
1 stop6h 12m
American Airlines
Sun 7/126:14 am
STL
- ROA
1 stop7h 10m
American Airlines
Deal found 7/3![American Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:59 pm
ROA
- MCI
1 stop4h 59m
Delta
Sat 7/181:17 pm
MCI
- ROA
1 stop7h 26m
Delta
Deal found 7/3![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/164:48 pm
ROA
- STL
1 stop4h 15m
American Airlines
Mon 7/206:13 pm
STL
- ROA
1 stop4h 46m
American Airlines
Deal found 7/1![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:48 am
ROA
- MCI
1 stop5h 30m
American Airlines
Fri 7/311:26 pm
MCI
- ROA
1 stop5h 37m
American Airlines
Deal found 7/3![American Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:40 am
ROA
- STL
1 stop4h 54m
United Airlines
Sun 7/261:13 pm
STL
- ROA
1 stop6h 50m
United Airlines
Deal found 7/6![United Airlines logo]()
$413
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:10 am
ROA
- MCI
1 stop5h 36m
American Airlines
Sat 8/16:21 pm
MCI
- ROA
1 stop4h 50m
American Airlines
Deal found 7/2![American Airlines logo]()
$308
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:57 pm
ROA
- STL
1 stop4h 56m
Delta
Mon 8/35:23 pm
STL
- ROA
1 stop6h 04m
Delta
Deal found 7/2![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:00 am
ROA
- SGF
1 stop5h 17m
American Airlines
Wed 8/512:23 pm
SGF
- ROA
1 stop5h 58m
American Airlines
Deal found 7/2![American Airlines logo]()
$356
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:35 pm
ROA
- SGF
1 stop6h 08m
American Airlines
Tue 8/113:01 pm
SGF
- ROA
1 stop5h 09m
American Airlines
Deal found 7/2![American Airlines logo]()
$335
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2610:26 am
ROA
- MCI
1 stop5h 24m
United Airlines
Sat 8/295:39 pm
MCI
- ROA
1 stop5h 04m
United Airlines
Deal found 7/2![United Airlines logo]()
$389
One-way flights from Roanoke to MissouriSearch for one-way flight options from Roanoke to Missouri. Find affordable one-way fares based on user searches. Data last updated July 6, 2026.
Search for one-way flight options from Roanoke to Missouri. Find affordable one-way fares based on user searches. Data last updated July 6, 2026.
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am
ROA
- MCI
1 stop6h 14m
Delta
Deal found 7/3![Delta logo]()
$269
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:53 pm
ROA
- STL
1 stop5h 05m
American Airlines
Deal found 7/2![American Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:35 pm
ROA
- SGF
1 stop6h 08m
American Airlines
Deal found 7/2![American Airlines logo]()
$293
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:04 am
ROA
- SGF
2 stops9h 06m
Delta
Deal found 7/6![Delta logo]()
$298
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:35 am
ROA
- MCI
2 stops13h 00m
United Airlines
Deal found 7/6![United Airlines logo]()
$314
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/274:48 pm
ROA
- MCI
2 stops8h 35m
American Airlines
Deal found 7/2![American Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:15 am
ROA
- SGF
2 stops10h 56m
United Airlines
Deal found 7/3![United Airlines logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/73:27 pm
ROA
- MCI
3 stops51h 52m
Allegiant Air
Deal found 7/5![Allegiant Air logo]()
$341
This Delta deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:04 am
ROA
- MCI
2 stops10h 09m
Delta
Deal found 7/5![Delta logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/274:40 pm
ROA
- MCI
3 stops45h 20m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$371
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:15 am
ROA
- MCI
2 stops7h 07m
United Airlines
Deal found 7/2![United Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1111:05 am
ROA
- MCI
1 stop6h 18m
American Airlines
Deal found 7/3![American Airlines logo]()
$395
Find flight deals from Roanoke to Missouri
Keep the following information in mind while searching for Roanoke to Missouri flight deals. Data was last updated July 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $308 (American Airlines) |
One-way from | $269 (Delta) |
Popular in | November |
Cheapest in | February |
Average price | $403 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 6, 2026.
Use the filters below to find and compare flights from Roanoke to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Fri 7/31
7:57 pm-11:53 pm
1 stop4h 56m
Lambert-St Louis
Mon 8/3
5:23 pm-12:27 am
1 stop6h 04m
$309
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Sun 8/2
7:53 pm-11:58 pm
1 stop5h 05m
Lambert-St Louis
Sat 8/8
1:54 pm-7:21 pm
1 stop4h 27m
$309
RoanokeSpringfield
ROA - SGF
ROASGF
Roanoke
Sat 9/5
5:02 pm-9:19 pm
1 stop5h 17m
Springfield-Branson
Mon 9/7
6:58 pm-12:27 am
1 stop4h 29m
$335
RoanokeSpringfield
ROA - SGF
ROASGF
Roanoke
Mon 11/9
6:00 am-11:11 am
1 stop6h 11m
Springfield-Branson
Sun 11/15
6:45 pm-12:23 am
1 stop4h 38m
$335
Quickest round-trip
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Thu 7/16
4:48 pm-8:03 pm
1 stop4h 15m
Lambert-St Louis
Mon 7/20
6:13 pm-11:59 pm
1 stop4h 46m
$339
RoanokeKansas City
ROA - MCI
ROAMCI
Roanoke
Wed 7/15
7:59 pm-11:58 pm
1 stop4h 59m
Kansas City
Sat 7/18
1:17 pm-9:43 pm
1 stop7h 26m
$369
RoanokeKansas City
ROA - MCI
ROAMCI
Roanoke
Wed 8/26
10:26 am-2:50 pm
1 stop5h 24m
Kansas City
Sat 8/29
5:39 pm-11:43 pm
1 stop5h 04m
$389
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Tue 9/1
6:40 am-12:02 pm
1 stop6h 22m
Lambert-St Louis
Sat 9/5
8:30 am-5:09 pm
1 stop7h 39m
$389
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Fri 7/24
6:40 am-10:34 am
1 stop4h 54m
Lambert-St Louis
Sun 7/26
1:13 pm-9:03 pm
1 stop6h 50m
$413
RoanokeSpringfield
ROA - SGF
ROASGF
Roanoke
Tue 9/29
6:49 am-10:45 am
1 stop4h 56m
Springfield-Branson
Sat 10/3
9:00 am-11:44 pm
2 stops13h 44m
$485
Showing 1-10 of 27 resultsSorted by cheapest first
Best time to book a flight from Roanoke to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Roanoke with our price prediction graph.
ROA-MCI
ROA-STL
ROA-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to Missouri
ROA-USMO
ROA-MCI
ROA-STL
ROA-SGF
What is the cheapest month to book a flight from Roanoke to Missouri?
Currently, November is the cheapest month in which you can book a flight from Roanoke to Missouri (average of $176). Flying from Roanoke to Missouri in June is currently the most expensive (average of $327). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Roanoke to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 6, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Roanoke to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Roanoke and Missouri flights
Browse other Roanoke and Missouri flight options. Last updated on July 6, 2026.
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Roanoke to Missouri flights
Consider these flights traveling from Roanoke to Missouri.
Top 3 airlines flying from Roanoke to Missouri
Discover the top 3 airlines that operate flights from Roanoke to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$176 | Average$483 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$432 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$254 | Average$381 | FlexibilityNo cancel fee | On-timeN/A |