$242+ Cheap flights from Roanoke (ROA) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/30. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — STL
Jun 16 — Jun 231
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to Missouri with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Roanoke to MissouriExplore the most affordable flight options available from Roanoke to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 17, 2026.
Explore the most affordable flight options available from Roanoke to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 17, 2026.
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:00 am
ROA
- MCI
1 stop4h 24m
Delta
Mon 8/35:19 pm
MCI
- ROA
1 stop5h 31m
Delta
Deal found 5/15![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:59 pm
ROA
- STL
1 stop4h 57m
Delta
Mon 7/67:12 pm
STL
- ROA
1 stop4h 20m
Delta
Deal found 5/13![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:51 pm
ROA
- STL
2 stops7h 25m
American Airlines
Mon 7/69:22 am
STL
- ROA
1 stop6h 54m
American Airlines
Deal found 5/16![American Airlines logo]()
$314
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:10 am
ROA
- MCI
1 stop5h 42m
American Airlines
Tue 6/305:17 pm
MCI
- ROA
1 stop5h 42m
American Airlines
Deal found 5/13![American Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:10 am
ROA
- MCI
1 stop5h 36m
American Airlines
Sat 7/186:21 pm
MCI
- ROA
1 stop4h 50m
American Airlines
Deal found 5/12![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:58 pm
ROA
- STL
1 stop4h 46m
American Airlines
Tue 6/98:57 am
STL
- ROA
1 stop7h 24m
American Airlines
Deal found 5/12![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:15 am
ROA
- MCI
2 stops9h 05m
United Airlines
Tue 6/305:45 pm
MCI
- ROA
1 stop4h 59m
United Airlines
Deal found 5/13![United Airlines logo]()
$323
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:00 am
ROA
- MCI
1 stop4h 24m
Delta
Mon 7/203:38 pm
MCI
- ROA
1 stop7h 12m
Delta
Deal found 5/15![Delta logo]()
$324
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:35 pm
ROA
- STL
1 stop5h 24m
Delta
Tue 6/97:12 pm
STL
- ROA
1 stop4h 20m
Delta
Deal found 5/14![Delta logo]()
$324
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:57 pm
ROA
- STL
1 stop4h 56m
Delta
Thu 7/236:58 pm
STL
- ROA
1 stop4h 27m
Delta
Deal found 5/16![Delta logo]()
$354
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:00 am
ROA
- STL
1 stop4h 44m
Delta
Tue 6/97:12 pm
STL
- ROA
1 stop4h 20m
Delta
Deal found 5/12![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:00 am
ROA
- MCI
2 stops14h 16m
Delta
Wed 8/57:07 am
MCI
- ROA
1 stop6h 44m
Delta
Deal found 5/15![Delta logo]()
$361
Best flights from Roanoke to MissouriDiscover carefully curated flight deals from Roanoke to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 17, 2026.
Discover carefully curated flight deals from Roanoke to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 17, 2026.
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
ROA
- STL
1 stop4h 44m
Delta
Wed 6/107:08 am
STL
- ROA
1 stop6h 40m
Delta
Deal found 5/14![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:51 pm
ROA
- STL
2 stops7h 25m
American Airlines
Mon 7/69:22 am
STL
- ROA
1 stop6h 54m
American Airlines
Deal found 5/16![American Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:40 am
ROA
- MCI
1 stop4h 45m
United Airlines
Sat 8/225:39 pm
MCI
- ROA
1 stop5h 04m
United Airlines
Deal found 5/12![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:57 pm
ROA
- STL
1 stop4h 56m
Delta
Wed 7/159:24 am
STL
- ROA
1 stop4h 23m
Delta
Deal found 5/15![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:57 pm
ROA
- STL
1 stop4h 56m
Delta
Thu 7/236:58 pm
STL
- ROA
1 stop4h 27m
Delta
Deal found 5/15![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:40 am
ROA
- MCI
1 stop4h 45m
United Airlines
Sat 8/297:30 am
MCI
- ROA
2 stops10h 37m
United Airlines
Deal found 5/16![United Airlines logo]()
$394
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:10 am
ROA
- MCI
1 stop5h 37m
American Airlines
Sat 6/66:21 pm
MCI
- ROA
1 stop5h 03m
American Airlines
Deal found 5/16![American Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:10 am
ROA
- MCI
1 stop5h 36m
American Airlines
Thu 7/305:21 pm
MCI
- ROA
1 stop4h 57m
American Airlines
Deal found 5/12![American Airlines logo]()
$425
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
ROA
- MCI
1 stop4h 29m
Delta
Sun 5/317:05 am
MCI
- ROA
1 stop6h 45m
Delta
Deal found 5/13![Delta logo]()
$427
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:40 am
ROA
- STL
1 stop6h 22m
United Airlines
Mon 8/318:00 am
STL
- ROA
2 stops14h 43m
United Airlines
Deal found 5/13![United Airlines logo]()
$534
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/910:30 am
ROA
- STL
3 stops26h 41m
United Airlines
Thu 7/231:13 pm
STL
- ROA
1 stop6h 50m
United Airlines
Deal found 5/16![United Airlines logo]()
$539
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:05 am
ROA
- STL
2 stops10h 05m
Delta
Tue 6/97:12 pm
STL
- ROA
1 stop4h 20m
Delta
Deal found 5/13![Delta logo]()
$509
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:05 am
ROA
- MCI
2 stops11h 26m
Delta
Sat 6/610:34 am
MCI
- ROA
1 stop4h 43m
Delta
Deal found 5/13![Delta logo]()
$523
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:15 am
ROA
- SGF
2 stops10h 55m
United Airlines
Mon 6/16:35 pm
SGF
- ROA
1 stop14h 11m
United Airlines
Deal found 5/13![United Airlines logo]()
$654
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:49 pm
ROA
- SGF
2 stops9h 55m
American Airlines
Thu 5/2812:46 pm
SGF
- ROA
2 stops8h 34m
American Airlines
Deal found 5/12![American Airlines logo]()
$761
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
ROA
- SGF
1 stop6h 27m
Delta
Thu 5/286:49 pm
SGF
- ROA
1 stop4h 45m
Delta
Deal found 5/12![Delta logo]()
$727
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:40 am
ROA
- SGF
1 stop5h 02m
United Airlines
Thu 5/283:07 pm
SGF
- ROA
1 stop4h 54m
United Airlines
Deal found 5/15![United Airlines logo]()
$813
Last-minute flights from Roanoke to MissouriDiscover last-minute flight deals from Roanoke to Missouri. Data last updated May 17, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Missouri. Data last updated May 17, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1910:51 am
ROA
- STL
1 stop4h 41m
United Airlines
Sat 5/2310:25 am
STL
- ROA
1 stop5h 46m
United Airlines
Deal found 5/15![United Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:00 am
ROA
- STL
1 stop4h 44m
Delta
Tue 6/97:12 pm
STL
- ROA
1 stop4h 20m
Delta
Deal found 5/12![Delta logo]()
$359
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:10 am
ROA
- MCI
1 stop5h 42m
American Airlines
Tue 6/305:17 pm
MCI
- ROA
1 stop5h 42m
American Airlines
Deal found 5/13![American Airlines logo]()
$318
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:15 am
ROA
- MCI
2 stops9h 05m
United Airlines
Tue 6/305:45 pm
MCI
- ROA
1 stop4h 59m
United Airlines
Deal found 5/13![United Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:10 am
ROA
- MCI
1 stop5h 37m
American Airlines
Sat 6/66:21 pm
MCI
- ROA
1 stop5h 03m
American Airlines
Deal found 5/16![American Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:58 pm
ROA
- STL
1 stop4h 46m
American Airlines
Tue 6/98:57 am
STL
- ROA
1 stop7h 24m
American Airlines
Deal found 5/12![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:35 pm
ROA
- STL
1 stop5h 24m
Delta
Tue 6/97:12 pm
STL
- ROA
1 stop4h 20m
Delta
Deal found 5/14![Delta logo]()
$324
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
ROA
- STL
1 stop4h 44m
Delta
Wed 6/107:08 am
STL
- ROA
1 stop6h 40m
Delta
Deal found 5/14![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:51 pm
ROA
- STL
2 stops7h 23m
American Airlines
Wed 6/109:23 am
STL
- ROA
1 stop7h 20m
American Airlines
Deal found 5/13![American Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:00 am
ROA
- STL
1 stop9h 02m
American Airlines
Thu 6/119:23 am
STL
- ROA
1 stop6h 54m
American Airlines
Deal found 5/14![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/178:10 am
ROA
- MCI
1 stop5h 26m
American Airlines
Sat 7/186:21 pm
MCI
- ROA
1 stop4h 50m
American Airlines
Deal found 5/16![American Airlines logo]()
$309
This deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/173:10 pm
ROA
- MCI
1 stop6h 03m
American Airlines
Sat 6/205:51 pm
MCI
- ROA
1 stop5h 33m
American Airlines
Deal found 5/15![American Airlines logo]()
$398
One-way flights from Roanoke to MissouriSearch for one-way flight options from Roanoke to Missouri. Find affordable one-way fares based on user searches. Data last updated May 17, 2026.
Search for one-way flight options from Roanoke to Missouri. Find affordable one-way fares based on user searches. Data last updated May 17, 2026.
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:00 am
ROA
- STL
1 stop11h 33m
American Airlines
Deal found 5/16![American Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:40 pm
ROA
- SGF
1 stop25h 49m
Allegiant Air
Deal found 5/13![Allegiant Air logo]()
$259
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1511:08 am
ROA
- SGF
1 stop6h 14m
American Airlines
Deal found 5/13![American Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:59 pm
ROA
- STL
1 stop4h 57m
Delta
Deal found 5/13![Delta logo]()
$269
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:00 am
ROA
- STL
1 stop6h 46m
Delta
Deal found 5/15![Delta logo]()
$279
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:05 am
ROA
- SGF
2 stops12h 08m
Delta
Deal found 5/15![Delta logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/92:46 pm
ROA
- STL
3 stops34h 13m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$298
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:40 am
ROA
- SGF
1 stop5h 08m
United Airlines
Deal found 5/13![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:15 am
ROA
- SGF
1 stop6h 31m
American Airlines
Deal found 5/12![American Airlines logo]()
$310
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:00 pm
ROA
- SGF
2 stops7h 52m
United Airlines
Deal found 5/13![United Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3010:30 am
ROA
- STL
3 stops26h 41m
United Airlines
Deal found 5/13![United Airlines logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/254:08 pm
ROA
- MCI
3 stops50h 21m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$325
Find flight deals from Roanoke to Missouri
Keep the following information in mind while searching for Roanoke to Missouri flight deals. Data was last updated May 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (Delta) |
One-way from | $242 (American Airlines) |
Popular in | April |
Cheapest in | February |
Average price | $396 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 17, 2026.
Use the filters below to find and compare flights from Roanoke to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Wed 6/3
6:00 am-9:44 am
1 stop4h 44m
Lambert-St Louis
Wed 6/10
7:08 am-2:48 pm
1 stop6h 40m
$309
Quickest round-trip
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Fri 7/10
7:57 pm-11:53 pm
1 stop4h 56m
Lambert-St Louis
Wed 7/15
9:24 am-2:47 pm
1 stop4h 23m
$309
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Wed 7/1
5:51 pm-12:16 am
2 stops7h 25m
Lambert-St Louis
Mon 7/6
9:22 am-5:16 pm
1 stop6h 54m
$314
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Thu 7/9
7:57 pm-11:53 pm
1 stop4h 56m
Lambert-St Louis
Thu 7/23
6:58 pm-12:25 am
1 stop4h 27m
$324
RoanokeKansas City
ROA - MCI
ROAMCI
Roanoke
Wed 8/19
6:40 am-10:25 am
1 stop4h 45m
Kansas City
Sat 8/22
5:39 pm-11:43 pm
1 stop5h 04m
$389
RoanokeKansas City
ROA - MCI
ROAMCI
Roanoke
Wed 8/26
6:40 am-10:25 am
1 stop4h 45m
Kansas City
Sat 8/29
7:30 am-7:07 pm
2 stops10h 37m
$394
RoanokeKansas City
ROA - MCI
ROAMCI
Roanoke
Sat 5/30
8:10 am-12:47 pm
1 stop5h 37m
Kansas City
Sat 6/6
6:21 pm-12:24 am
1 stop5h 03m
$405
RoanokeKansas City
ROA - MCI
ROAMCI
Roanoke
Fri 7/24
8:10 am-12:46 pm
1 stop5h 36m
Kansas City
Thu 7/30
5:21 pm-11:18 pm
1 stop4h 57m
$425
RoanokeKansas City
ROA - MCI
ROAMCI
Roanoke
Fri 5/29
6:00 am-9:29 am
1 stop4h 29m
Kansas City
Sun 5/31
7:05 am-2:50 pm
1 stop6h 45m
$427
RoanokeSt. Louis
ROA - STL
ROASTL
Roanoke
Tue 6/2
7:05 am-4:10 pm
2 stops10h 05m
Lambert-St Louis
Tue 6/9
7:12 pm-12:32 am
1 stop4h 20m
$509
Showing 1-10 of 29 resultsSorted by cheapest first
Best time to book a flight from Roanoke to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Roanoke with our price prediction graph.
ROA-STL
ROA-MCI
ROA-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to Missouri
ROA-USMO
ROA-STL
ROA-MCI
ROA-SGF
What is the cheapest month to book a flight from Roanoke to Missouri?
Currently, November is the cheapest month in which you can book a flight from Roanoke to Missouri (average of $176). Flying from Roanoke to Missouri in March is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Roanoke to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated May 17, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Roanoke to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Roanoke and Missouri flights
Browse other Roanoke and Missouri flight options. Last updated on May 17, 2026.
Popular flight searches
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Roanoke to Missouri flights
Consider these flights traveling from Roanoke to Missouri.
Top 3 airlines flying from Roanoke to Missouri
Discover the top 3 airlines that operate flights from Roanoke to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$176 | Average$524 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$410 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$353 | FlexibilityNo cancel fee | On-timeN/A |