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$220+ Cheap flights from Roanoke (ROA) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — JAN
May 20 — May 271
Tue 5/20
Tue 5/27
1 adult, Economy
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Cheap flight deals from Roanoke to Mississippi

Keep the following information in mind while searching for Roanoke to Mississippi flight deals. Data was last updated May 15, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$249
(Delta)

One-way from

$220
(Delta)
Provider with most accurate pricing for Roanoke-Jackson-Evers Intl flight deals.
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Provider most trusted by Cheapflights users for Roanoke-Jackson-Evers Intl flights.
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From Roanoke to Mississippi
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One-way flight from Roanoke to Mississippi
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Find flight deals from Roanoke to Mississippi

Cheapest flights from Roanoke to Mississippi
Explore the most affordable flight options available from Roanoke to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 15, 2025.

This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/136:00 amROA - MEM
1 stop3h 50mDelta
Fri 6/207:25 pmMEM - ROA
1 stop3h 58mDelta
Deal found 5/14$249
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/76:18 pmROA - MOB
1 stop4h 26mAmerican Airlines
Thu 6/125:00 pmMOB - ROA
1 stop5h 45mAmerican Airlines
Deal found 5/14$294
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/227:30 amROA - MEM
1 stop6h 21mAmerican Airlines
Tue 5/277:25 amMEM - ROA
1 stop3h 58mAmerican Airlines
Deal found 5/14$309
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/234:22 pmROA - JAN
1 stop6h 39mAmerican Airlines
Sun 5/257:20 amJAN - ROA
2 stops8h 12mAmerican Airlines
Deal found 5/15$314
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/225:35 pmROA - MEM
1 stop5h 55mUnited Airlines
Tue 5/276:00 amMEM - ROA
2 stops11h 46mUnited Airlines
Deal found 5/14$314
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/306:00 amROA - JAN
1 stop3h 29mDelta
Tue 6/35:55 amJAN - ROA
1 stop3h 36mDelta
Deal found 5/15$319
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/306:20 amROA - MOB
1 stop4h 46mUnited Airlines
Tue 6/38:00 amMOB - ROA
1 stop4h 59mUnited Airlines
Deal found 5/15$354
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/188:11 pmROA - GTR
2 stops19h 40mAmerican Airlines
Mon 7/213:21 pmGTR - ROA
2 stops20h 15mAmerican Airlines
Deal found 5/15$482
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/183:45 pmROA - GTR
1 stop6h 43mDelta
Mon 7/212:17 pmGTR - ROA
1 stop4h 15mDelta
Deal found 5/15$548
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/307:40 pmROA - JAN
2 stops18h 49mUnited Airlines
Tue 6/39:00 amJAN - ROA
2 stops13h 35mUnited Airlines
Deal found 5/15$750

Cheapflights Fare Finder

Customize your flight search to find flights from Roanoke to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 15, 2025.
Use the filters below to find and compare flights from Roanoke to Mississippi that are best for you.

Fly from

Roanoke

Fly to

Mississippi

Route

Depart

Return

Price

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Fri 6/13

6:00 am-8:50 am

1 stop3h 50m

Memphis

Fri 6/20

7:25 pm-12:23 am

1 stop3h 58m

$249

RoanokeMobile

ROA - MOB

ROAMOB

Roanoke

Sat 6/7

6:18 pm-9:44 pm

1 stop4h 26m

Mobile

Thu 6/12

5:00 pm-11:45 pm

1 stop5h 45m

$294

RoanokeJackson

ROA - JAN

ROAJAN

Roanoke

Fri 5/30

6:00 am-8:29 am

1 stop3h 29m

Jackson-Evers Intl

Tue 6/3

5:55 am-10:31 am

1 stop3h 36m

$319

RoanokeJackson

ROA - JAN

ROAJAN

Roanoke

Fri 5/30

5:03 pm-11:55 pm

2 stops7h 52m

Jackson-Evers Intl

Tue 6/3

5:10 am-12:23 pm

1 stop6h 13m

$324

RoanokeMobile

ROA - MOB

ROAMOB

Roanoke

Fri 5/30

6:20 am-10:06 am

1 stop4h 46m

Mobile

Tue 6/3

8:00 am-1:59 pm

1 stop4h 59m

$354

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Thu 5/29

7:00 am-11:02 am

1 stop5h 02m

Memphis

Mon 6/2

2:48 pm-9:05 pm

1 stop5h 17m

$379

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Fri 6/13

5:25 pm-11:19 pm

2 stops6h 54m

Memphis

Fri 6/20

6:42 pm-11:45 pm

1 stop4h 03m

$427

RoanokeColumbus

ROA - GTR

ROAGTR

Roanoke

Fri 7/18

8:11 pm-2:51 pm

2 stops19h 40m

Columbus Golden Triangle Reg.

Mon 7/21

3:21 pm-12:36 pm

2 stops20h 15m

$482

RoanokeColumbus

ROA - GTR

ROAGTR

Roanoke

Fri 7/18

3:45 pm-9:28 pm

1 stop6h 43m

Columbus Golden Triangle Reg.

Mon 7/21

2:17 pm-7:32 pm

1 stop4h 15m

$548

RoanokeJackson

ROA - JAN

ROAJAN

Roanoke

Fri 5/30

7:40 pm-1:29 pm

2 stops18h 49m

Jackson-Evers Intl

Tue 6/3

9:00 am-11:35 pm

2 stops13h 35m

$750

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/14

Showing 1-10 of 12 results
1
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Best time to book a flight from Roanoke to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Mississippi

What is the cheapest month to book a flight from Roanoke to Mississippi?

Currently, January is the cheapest month in which you can book a flight from Roanoke to Mississippi (average of $371). Flying from Roanoke to Mississippi in March is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to MS?

Find hourly flight availability from Roanoke to Mississippi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Roanoke to Mississippi as you normally would.

Rainfall in Mississippi by month

Plan your trip to Mississippi by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mississippi ranges from 2.2 - 5.6 inches per month. December is typically the wettest month, when rainfall can reach 5.6 in. October is typically the driest time to visit Mississippi when rainfall is around 2.2 in.

Temperature in Mississippi by month

Plan your trip to Mississippi by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mississippi, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated May 15, 2025.
To help decide which airline to fly from Roanoke to Mississippi, see what other customers have to say about Delta, United Airlines and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,946 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,731 reviews
Delta
8.0
Very good
7,946 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,946 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to Mississippi?

    Most people fly from Roanoke (ROA) if they book a flight from Roanoke to Mississippi. Roanoke is conveniently located just 4.2 mi from Roanoke’s city center.

  • What are the most popular routes from Roanoke to Mississippi?

    Most travelers choose Roanoke - Memphis, Roanoke - Jackson-Evers Intl or Roanoke - Mobile when deciding on the best route from Roanoke to Mississippi.

  • Can I find deals for flights from Roanoke to Mississippi that include hotel bookings?

    Yes. In addition to deals on Roanoke to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Mississippi.

  • Can I find deals for business class flights from Roanoke to Mississippi?

    Yes. Cheapflights offers flight deals from Roanoke to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from Roanoke to Mississippi (average of $371). Flying from Roanoke to Mississippi in March is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Roanoke to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Roanoke to Mississippi

Discover the top 2 airlines that operate flights from Roanoke to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$366FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$353Average$394FlexibilityNo cancel feeOn-time71%

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