$296+ Cheap flights from Roanoke (ROA) to Mississippi
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/26. Fares are subject to change and may not be available on all flights or dates of travel.
ROA ā JAN
Aug 8 ā Aug 151
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to Mississippi with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click āFind dealsā2. Select your favorite providers
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Review each providerās pricing and select the best option for you! Book through your favorite providerās website for a seamless experience.Cheap flight deals from Roanoke to Mississippi
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Cheapest flights from Roanoke to MississippiExplore the most affordable flight options available from Roanoke to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 9, 2026.
Explore the most affordable flight options available from Roanoke to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 9, 2026.
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Tue 8/45:52 pm
ROA
- MEM
1 stop6h 29m
United Airlines
Tue 8/119:47 am
MEM
- ROA
1 stop6h 20m
United Airlines
Deal found 7/5![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 7/5. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Thu 8/206:00 am
ROA
- MOB
1 stop6h 20m
Delta
Sun 8/236:00 am
MOB
- ROA
1 stop3h 37m
Delta
Deal found 7/5![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 7/9. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Fri 9/186:00 am
ROA
- MOB
1 stop6h 22m
Delta
Sun 9/206:10 pm
MOB
- ROA
1 stop4h 49m
Delta
Deal found 7/9![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Wed 8/56:40 am
ROA
- MEM
1 stop5h 25m
United Airlines
Wed 8/127:15 am
MEM
- ROA
2 stops10h 52m
United Airlines
Deal found 7/8![United Airlines logo]()
$336
This Delta deal was found by Cheapflights users on 7/8. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Thu 7/237:57 pm
ROA
- MOB
1 stop4h 28m
Delta
Mon 7/276:58 pm
MOB
- ROA
1 stop4h 27m
Delta
Deal found 7/8![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 7/5. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Wed 7/296:00 am
ROA
- MEM
1 stop4h 27m
Delta
Sat 8/13:54 pm
MEM
- ROA
1 stop4h 49m
Delta
Deal found 7/5![Delta logo]()
$345
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure American Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 7/255:00 am
ROA
- MEM
1 stop6h 34m
American Airlines
Fri 7/312:56 pm
MEM
- ROA
1 stop5h 24m
American Airlines
Deal found 7/8![American Airlines logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Kiwi.com is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/103:27 pm
ROA
- MEM
1 stop25h 14m
Multiple Airlines
Thu 8/137:10 pm
MEM
- ROA
1 stop18h 27m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 7/6. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 7/185:00 pm
ROA
- MOB
1 stop4h 53m
Delta
Fri 7/246:58 pm
MOB
- ROA
1 stop4h 27m
Delta
Deal found 7/6![Delta logo]()
$369
This Delta deal was found by Cheapflights users on 7/4. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 7/187:00 am
ROA
- MEM
1 stop4h 32m
Delta
Wed 7/225:52 pm
MEM
- ROA
1 stop5h 33m
Delta
Deal found 7/4![Delta logo]()
$379
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 11/145:51 pm
ROA
- MEM
1 stop6h 44m
United Airlines
Wed 11/187:02 am
MEM
- ROA
1 stop5h 24m
United Airlines
Deal found 7/7![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Tue 8/253:00 pm
ROA
- MOB
1 stop6h 18m
United Airlines
Sat 8/2912:33 pm
MOB
- ROA
1 stop5h 34m
United Airlines
Deal found 7/5![United Airlines logo]()
$389
Best flights from Roanoke to MississippiDiscover carefully curated flight deals from Roanoke to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 9, 2026.
Discover carefully curated flight deals from Roanoke to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 9, 2026.
This Delta deal was found by Cheapflights users on 7/5. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Thu 8/206:00 am
ROA
- MOB
1 stop6h 20m
Delta
Sun 8/236:00 am
MOB
- ROA
1 stop3h 37m
Delta
Deal found 7/5![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Thu 8/205:50 pm
ROA
- MEM
1 stop6h 28m
United Airlines
Mon 8/247:15 am
MEM
- ROA
2 stops10h 52m
United Airlines
Deal found 7/7![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 7/4. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sun 11/86:00 am
ROA
- MOB
1 stop3h 30m
Delta
Sat 11/1412:10 pm
MOB
- ROA
1 stop6h 03m
Delta
Deal found 7/4![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Tue 8/45:52 pm
ROA
- MEM
1 stop6h 29m
United Airlines
Tue 8/119:47 am
MEM
- ROA
2 stops8h 20m
United Airlines
Deal found 7/6![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 7/9. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Fri 9/186:00 am
ROA
- MOB
1 stop6h 22m
Delta
Sun 9/206:10 pm
MOB
- ROA
1 stop4h 49m
Delta
Deal found 7/9![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Wed 8/56:40 am
ROA
- MEM
1 stop5h 25m
United Airlines
Wed 8/127:15 am
MEM
- ROA
2 stops10h 52m
United Airlines
Deal found 7/8![United Airlines logo]()
$336
This Delta deal was found by Cheapflights users on 7/8. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Thu 7/237:57 pm
ROA
- MOB
1 stop4h 28m
Delta
Mon 7/276:58 pm
MOB
- ROA
1 stop4h 27m
Delta
Deal found 7/8![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 7/4. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/36:00 am
ROA
- MEM
1 stop5h 39m
Delta
Mon 8/104:59 pm
MEM
- ROA
1 stop6h 28m
Delta
Deal found 7/4![Delta logo]()
$345
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 11/145:51 pm
ROA
- MEM
1 stop6h 44m
United Airlines
Wed 11/187:02 am
MEM
- ROA
1 stop5h 24m
United Airlines
Deal found 7/8![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 7/4. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Fri 8/147:59 pm
ROA
- MEM
1 stop4h 25m
Delta
Mon 8/174:59 pm
MEM
- ROA
1 stop6h 28m
Delta
Deal found 7/4![Delta logo]()
$345
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Tue 8/253:00 pm
ROA
- MOB
1 stop6h 18m
United Airlines
Sat 8/2912:33 pm
MOB
- ROA
1 stop5h 34m
United Airlines
Deal found 7/6![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Tue 8/255:50 pm
ROA
- JAN
2 stops23h 35m
United Airlines
Sat 8/297:00 am
JAN
- ROA
2 stops15h 43m
United Airlines
Deal found 7/4![United Airlines logo]()
$752
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sun 7/196:15 am
ROA
- JAN
2 stops16h 39m
United Airlines
Thu 7/235:10 pm
JAN
- ROA
2 stops15h 36m
United Airlines
Deal found 7/4![United Airlines logo]()
$1,305
Last-minute flights from Roanoke to MississippiDiscover last-minute flight deals from Roanoke to Mississippi. Data last updated July 9, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Mississippi. Data last updated July 9, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Tue 7/1410:47 am
ROA
- MEM
1 stop4h 55m
United Airlines
Sat 7/189:54 am
MEM
- ROA
1 stop6h 17m
United Airlines
Deal found 7/6![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 7/6. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 7/185:00 pm
ROA
- MOB
1 stop4h 53m
Delta
Fri 7/246:58 pm
MOB
- ROA
1 stop4h 27m
Delta
Deal found 7/6![Delta logo]()
$369
This Delta deal was found by Cheapflights users on 7/4. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 7/187:00 am
ROA
- MEM
1 stop4h 32m
Delta
Wed 7/225:52 pm
MEM
- ROA
1 stop5h 33m
Delta
Deal found 7/4![Delta logo]()
$379
This Delta deal was found by Cheapflights users on 7/8. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Thu 7/237:57 pm
ROA
- MOB
1 stop4h 28m
Delta
Mon 7/276:58 pm
MOB
- ROA
1 stop4h 27m
Delta
Deal found 7/8![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure American Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 7/255:00 am
ROA
- MEM
1 stop6h 34m
American Airlines
Fri 7/312:56 pm
MEM
- ROA
1 stop5h 24m
American Airlines
Deal found 7/8![American Airlines logo]()
$362
This Delta deal was found by Cheapflights users on 7/5. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Wed 7/296:00 am
ROA
- MEM
1 stop4h 27m
Delta
Sat 8/13:54 pm
MEM
- ROA
1 stop4h 49m
Delta
Deal found 7/5![Delta logo]()
$345
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Tue 8/45:52 pm
ROA
- MEM
1 stop6h 29m
United Airlines
Tue 8/119:47 am
MEM
- ROA
1 stop6h 20m
United Airlines
Deal found 7/5![United Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Wed 8/56:40 am
ROA
- MEM
1 stop5h 25m
United Airlines
Wed 8/127:15 am
MEM
- ROA
2 stops10h 52m
United Airlines
Deal found 7/8![United Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Kiwi.com is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/103:27 pm
ROA
- MEM
1 stop25h 14m
Multiple Airlines
Thu 8/137:10 pm
MEM
- ROA
1 stop18h 27m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 7/5. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Thu 8/206:00 am
ROA
- MOB
1 stop6h 20m
Delta
Sun 8/236:00 am
MOB
- ROA
1 stop3h 37m
Delta
Deal found 7/5![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Tue 8/253:00 pm
ROA
- MOB
1 stop6h 18m
United Airlines
Sat 8/2912:33 pm
MOB
- ROA
1 stop5h 34m
United Airlines
Deal found 7/5![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 8/2910:44 am
ROA
- MEM
1 stop5h 02m
United Airlines
Wed 9/29:47 am
MEM
- ROA
1 stop6h 22m
United Airlines
Deal found 7/4![United Airlines logo]()
$389
One-way flights from Roanoke to MississippiSearch for one-way flight options from Roanoke to Mississippi. Find affordable one-way fares based on user searches. Data last updated July 9, 2026.
Search for one-way flight options from Roanoke to Mississippi. Find affordable one-way fares based on user searches. Data last updated July 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Kiwi.com is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sun 7/262:56 pm
ROA
- MEM
1 stop5h 54m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$296
This American Airlines deal was found by Cheapflights users on 7/4. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure American Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/37:53 pm
ROA
- MEM
1 stop4h 52m
American Airlines
Deal found 7/4![American Airlines logo]()
$302
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sun 7/266:15 am
ROA
- MEM
2 stops9h 27m
United Airlines
Deal found 7/8![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 7/5. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure American Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 7/187:53 pm
ROA
- JAN
1 stop4h 55m
American Airlines
Deal found 7/5![American Airlines logo]()
$387
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Kiwi.com is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sun 7/262:56 pm
ROA
- MEM
3 stops29h 07m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$492
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 7/1810:30 am
ROA
- JAN
3 stops12h 24m
United Airlines
Deal found 7/5![United Airlines logo]()
$653
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/32:30 pm
ROA
- MEM
3 stops25h 56m
United Airlines
Deal found 7/4![United Airlines logo]()
$921
Find flight deals from Roanoke to Mississippi
Keep the following information in mind while searching for Roanoke to Mississippi flight deals. Data was last updated July 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (United Airlines) |
One-way from | $296 (Kiwi.com) |
Cheapflights Fare Finder
Ā
Customize your flight search to find flights from Roanoke to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 9, 2026.
Use the filters below to find and compare flights from Roanoke to Mississippi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeMobile
ROA - MOB
ROAMOB
Roanoke
Thu 8/20
6:00 am-11:20 am
1 stop6h 20m
Mobile
Sun 8/23
6:00 am-10:37 am
1 stop3h 37m
$309
RoanokeMobile
ROA - MOB
ROAMOB
Roanoke
Sun 11/8
6:00 am-8:30 am
1 stop3h 30m
Mobile
Sat 11/14
12:10 pm-7:13 pm
1 stop6h 03m
$309
RoanokeMemphis
ROA - MEM
ROAMEM
Roanoke
Thu 8/20
5:50 pm-11:18 pm
1 stop6h 28m
Memphis
Mon 8/24
7:15 am-7:07 pm
2 stops10h 52m
$314
RoanokeMemphis
ROA - MEM
ROAMEM
Roanoke
Tue 8/4
5:52 pm-11:21 pm
1 stop6h 29m
Memphis
Tue 8/11
9:47 am-7:07 pm
2 stops8h 20m
$314
RoanokeMobile
ROA - MOB
ROAMOB
Roanoke
Fri 9/18
6:00 am-11:22 am
1 stop6h 22m
Mobile
Sun 9/20
6:10 pm-11:59 pm
1 stop4h 49m
$324
RoanokeMemphis
ROA - MEM
ROAMEM
Roanoke
Wed 8/5
6:40 am-11:05 am
1 stop5h 25m
Memphis
Wed 8/12
7:15 am-7:07 pm
2 stops10h 52m
$336
Quickest round-trip
RoanokeMobile
ROA - MOB
ROAMOB
Roanoke
Thu 7/23
7:57 pm-11:25 pm
1 stop4h 28m
Mobile
Mon 7/27
6:58 pm-12:25 am
1 stop4h 27m
$339
RoanokeMemphis
ROA - MEM
ROAMEM
Roanoke
Mon 8/3
6:00 am-10:39 am
1 stop5h 39m
Memphis
Mon 8/10
4:59 pm-12:27 am
1 stop6h 28m
$345
RoanokeMemphis
ROA - MEM
ROAMEM
Roanoke
Fri 8/14
7:59 pm-11:24 pm
1 stop4h 25m
Memphis
Mon 8/17
4:59 pm-12:27 am
1 stop6h 28m
$345
RoanokeMemphis
ROA - MEM
ROAMEM
Roanoke
Sat 11/14
5:51 pm-11:35 pm
1 stop6h 44m
Memphis
Wed 11/18
7:02 am-1:26 pm
1 stop5h 24m
$389
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Roanoke to Mississippi
Have a flexible travel schedule? Discover the best time to fly to Mississippi from Roanoke with our price prediction graph.
ROA-MEM
ROA-MOB
ROA-JAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to Mississippi
ROA-USMS
ROA-MEM
ROA-MOB
ROA-JAN
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Mississippi
Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated July 9, 2026.
Read through reviews of airlines operating flights from Roanoke to Mississippi, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Roanoke to Mississippi
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Complete your trip
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Roanoke and Mississippi flights
Browse other Roanoke and Mississippi flight options. Last updated on July 9, 2026.
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Roanoke to Mississippi flights
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Top 2 airlines flying from Roanoke to Mississippi
Discover the top 2 airlines that operate flights from Roanoke to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$386 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$262 | Average$438 | FlexibilityNo cancel fee | On-timeN/A |