$182+ Cheap flights from Roanoke (ROA) to Mississippi
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/14. Fares are subject to change and may not be available on all flights or dates of travel.
ROA ā JAN
Aug 22 ā Aug 291
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to Mississippi with Cheapflights
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Cheapest flights from Roanoke to MississippiExplore the most affordable flight options available from Roanoke to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.
Explore the most affordable flight options available from Roanoke to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.
This Delta deal was found by Cheapflights users on 7/18. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/1011:18 am
ROA
- JAN
1 stop4h 26m
Delta
Mon 8/171:00 pm
JAN
- ROA
1 stop5h 19m
Delta
Deal found 7/18![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure American Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Thu 8/132:23 pm
ROA
- MOB
1 stop7h 13m
American Airlines
Tue 8/186:27 am
MOB
- ROA
1 stop6h 26m
American Airlines
Deal found 7/21![American Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 7/22. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/173:32 pm
ROA
- JAN
1 stop6h 11m
Delta
Mon 8/241:00 pm
JAN
- ROA
1 stop5h 19m
Delta
Deal found 7/22![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Wed 8/53:32 pm
ROA
- JAN
1 stop5h 33m
Delta
Sun 8/99:15 am
JAN
- ROA
1 stop4h 36m
Delta
Deal found 7/19![Delta logo]()
$324
This Delta deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Thu 9/311:18 am
ROA
- MEM
1 stop5h 19m
Delta
Mon 9/147:19 pm
MEM
- ROA
1 stop3h 40m
Delta
Deal found 7/19![Delta logo]()
$335
This Delta deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Tue 8/46:00 am
ROA
- JAN
1 stop5h 37m
Delta
Sat 8/83:05 pm
JAN
- ROA
1 stop5h 33m
Delta
Deal found 7/19![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure American Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Thu 9/175:07 pm
ROA
- MEM
1 stop6h 47m
American Airlines
Sun 9/205:16 am
MEM
- ROA
1 stop6h 07m
American Airlines
Deal found 7/22![American Airlines logo]()
$345
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 8/16:40 am
ROA
- MEM
1 stop5h 25m
United Airlines
Mon 8/319:47 am
MEM
- ROA
1 stop6h 22m
United Airlines
Deal found 7/19![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 7/21. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Wed 8/56:00 am
ROA
- MOB
1 stop6h 20m
Delta
Sun 8/99:15 am
MOB
- ROA
1 stop4h 36m
Delta
Deal found 7/21![Delta logo]()
$363
This Delta deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/316:00 am
ROA
- MEM
1 stop5h 39m
Delta
Sun 9/1310:30 am
MEM
- ROA
1 stop6h 22m
Delta
Deal found 7/19![Delta logo]()
$367
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure American Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Wed 8/510:35 am
ROA
- MEM
1 stop5h 04m
American Airlines
Sun 8/97:07 am
MEM
- ROA
1 stop4h 18m
American Airlines
Deal found 7/21![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sun 9/66:00 am
ROA
- MEM
1 stop5h 39m
Delta
Fri 9/1110:30 am
MEM
- ROA
1 stop4h 22m
Delta
Deal found 7/19![Delta logo]()
$377
Best flights from Roanoke to MississippiDiscover carefully curated flight deals from Roanoke to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 23, 2026.
Discover carefully curated flight deals from Roanoke to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 23, 2026.
This Delta deal was found by Cheapflights users on 7/18. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/1011:18 am
ROA
- JAN
1 stop4h 26m
Delta
Mon 8/171:00 pm
JAN
- ROA
1 stop5h 19m
Delta
Deal found 7/18![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure American Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Thu 8/132:23 pm
ROA
- MOB
1 stop7h 13m
American Airlines
Tue 8/186:27 am
MOB
- ROA
1 stop6h 26m
American Airlines
Deal found 7/21![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 8/223:00 pm
ROA
- MEM
2 stops9h 18m
United Airlines
Sun 8/239:47 am
MEM
- ROA
1 stop6h 22m
United Airlines
Deal found 7/20![United Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure American Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Fri 8/145:03 pm
ROA
- MOB
1 stop4h 33m
American Airlines
Sun 8/164:36 pm
MOB
- ROA
1 stop4h 18m
American Airlines
Deal found 7/21![American Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Fri 9/116:00 am
ROA
- MEM
1 stop4h 22m
Delta
Sat 9/124:49 pm
MEM
- ROA
1 stop4h 02m
Delta
Deal found 7/19![Delta logo]()
$335
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure American Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Thu 9/36:15 am
ROA
- MEM
1 stop4h 18m
American Airlines
Sun 9/67:00 am
MEM
- ROA
1 stop4h 25m
American Airlines
Deal found 7/22![American Airlines logo]()
$335
This Delta deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Wed 8/511:18 am
ROA
- JAN
1 stop5h 58m
Delta
Sat 8/85:01 pm
JAN
- ROA
1 stop3h 37m
Delta
Deal found 7/19![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 10/316:40 am
ROA
- MEM
1 stop5h 06m
United Airlines
Tue 11/32:37 pm
MEM
- ROA
1 stop5h 09m
United Airlines
Deal found 7/20![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Tue 8/255:50 pm
ROA
- MEM
1 stop6h 28m
United Airlines
Sat 8/299:47 am
MEM
- ROA
1 stop6h 22m
United Airlines
Deal found 7/18![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Fri 9/116:00 am
ROA
- MEM
1 stop4h 22m
Delta
Fri 9/114:49 pm
MEM
- ROA
1 stop4h 02m
Delta
Deal found 7/19![Delta logo]()
$377
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/313:00 pm
ROA
- MEM
2 stops9h 17m
United Airlines
Sat 9/127:00 am
MEM
- ROA
2 stops11h 07m
United Airlines
Deal found 7/19![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure American Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/105:07 pm
ROA
- JAN
1 stop6h 32m
American Airlines
Mon 8/176:00 am
JAN
- ROA
2 stops10h 17m
American Airlines
Deal found 7/18![American Airlines logo]()
$594
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Thu 8/1310:26 am
ROA
- MOB
2 stops9h 07m
United Airlines
Tue 8/189:00 am
MOB
- ROA
2 stops10h 59m
United Airlines
Deal found 7/21![United Airlines logo]()
$552
This Delta deal was found by Cheapflights users on 7/22. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Tue 9/15:02 pm
ROA
- GTR
1 stop5h 32m
Delta
Fri 9/46:00 am
GTR
- ROA
1 stop3h 37m
Delta
Deal found 7/22![Delta logo]()
$614
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure American Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Tue 9/16:05 am
ROA
- GTR
2 stops10h 13m
American Airlines
Fri 9/43:48 pm
GTR
- ROA
1 stop30h 02m
American Airlines
Deal found 7/22![American Airlines logo]()
$642
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/178:05 pm
ROA
- JAN
2 stops18h 18m
United Airlines
Mon 8/245:20 pm
JAN
- ROA
2 stops22h 47m
United Airlines
Deal found 7/22![United Airlines logo]()
$605
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Wed 12/95:38 pm
ROA
- JAN
2 stops28h 40m
United Airlines
Sat 12/125:20 pm
JAN
- ROA
2 stops19h 13m
United Airlines
Deal found 7/20![United Airlines logo]()
$679
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 12/1210:20 am
ROA
- MOB
2 stops8h 57m
United Airlines
Wed 12/1612:55 pm
MOB
- ROA
1 stop4h 43m
United Airlines
Deal found 7/20![United Airlines logo]()
$680
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 12/1210:20 am
ROA
- MOB
2 stops8h 57m
United Airlines
Tue 12/153:10 pm
MOB
- ROA
2 stops21h 48m
United Airlines
Deal found 7/22![United Airlines logo]()
$736
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Wed 8/56:15 am
ROA
- JAN
2 stops16h 39m
United Airlines
Sun 8/92:07 pm
JAN
- ROA
2 stops18h 35m
United Airlines
Deal found 7/19![United Airlines logo]()
$895
Last-minute flights from Roanoke to MississippiDiscover last-minute flight deals from Roanoke to Mississippi. Data last updated July 23, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Mississippi. Data last updated July 23, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 8/16:40 am
ROA
- MEM
1 stop5h 25m
United Airlines
Mon 8/319:47 am
MEM
- ROA
1 stop6h 22m
United Airlines
Deal found 7/19![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Tue 8/46:00 am
ROA
- JAN
1 stop5h 37m
Delta
Sat 8/83:05 pm
JAN
- ROA
1 stop5h 33m
Delta
Deal found 7/19![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Wed 8/53:32 pm
ROA
- JAN
1 stop5h 33m
Delta
Sun 8/99:15 am
JAN
- ROA
1 stop4h 36m
Delta
Deal found 7/19![Delta logo]()
$324
This Delta deal was found by Cheapflights users on 7/21. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Wed 8/56:00 am
ROA
- MOB
1 stop6h 20m
Delta
Sun 8/99:15 am
MOB
- ROA
1 stop4h 36m
Delta
Deal found 7/21![Delta logo]()
$363
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure American Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Wed 8/510:35 am
ROA
- MEM
1 stop5h 04m
American Airlines
Sun 8/97:07 am
MEM
- ROA
1 stop4h 18m
American Airlines
Deal found 7/21![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 7/18. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/1011:18 am
ROA
- JAN
1 stop4h 26m
Delta
Mon 8/171:00 pm
JAN
- ROA
1 stop5h 19m
Delta
Deal found 7/18![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure American Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Thu 8/132:23 pm
ROA
- MOB
1 stop7h 13m
American Airlines
Tue 8/186:27 am
MOB
- ROA
1 stop6h 26m
American Airlines
Deal found 7/21![American Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 7/22. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/173:32 pm
ROA
- JAN
1 stop6h 11m
Delta
Mon 8/241:00 pm
JAN
- ROA
1 stop5h 19m
Delta
Deal found 7/22![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sat 8/223:00 pm
ROA
- MEM
2 stops9h 18m
United Airlines
Sun 8/239:47 am
MEM
- ROA
1 stop6h 22m
United Airlines
Deal found 7/20![United Airlines logo]()
$379
This Delta deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/316:00 am
ROA
- MEM
1 stop5h 39m
Delta
Thu 9/1010:30 am
MEM
- ROA
1 stop4h 22m
Delta
Deal found 7/19![Delta logo]()
$335
This Delta deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/316:00 am
ROA
- MEM
1 stop5h 39m
Delta
Sun 9/1310:30 am
MEM
- ROA
1 stop6h 22m
Delta
Deal found 7/19![Delta logo]()
$367
This Delta deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Mon 8/316:00 am
ROA
- MEM
1 stop5h 39m
Delta
Wed 9/96:45 am
MEM
- ROA
2 stops14h 06m
Delta
Deal found 7/19![Delta logo]()
$380
One-way flights from Roanoke to MississippiSearch for one-way flight options from Roanoke to Mississippi. Find affordable one-way fares based on user searches. Data last updated July 23, 2026.
Search for one-way flight options from Roanoke to Mississippi. Find affordable one-way fares based on user searches. Data last updated July 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Kiwi.com is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Fri 8/143:27 pm
ROA
- MEM
2 stops43h 43m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$182
This Delta deal was found by Cheapflights users on 7/20. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Delta is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Wed 8/127:59 pm
ROA
- JAN
1 stop4h 12m
Delta
Deal found 7/20![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Fri 8/145:50 pm
ROA
- MEM
1 stop6h 28m
United Airlines
Deal found 7/19![United Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sun 8/25:52 pm
ROA
- MEM
1 stop6h 29m
United Airlines
Deal found 7/21![United Airlines logo]()
$424
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure United Airlines is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Wed 8/1210:38 am
ROA
- JAN
2 stops30h 47m
United Airlines
Deal found 7/20![United Airlines logo]()
$461
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the āPick Datesā button in this card will allow you to select your dates and further customize your flight criteria. From there, click āFind dealsā, make sure Kiwi.com is selected, and click āCompare selectedā under the list of providers to see comparable flight deals.
Sun 8/22:46 pm
ROA
- MEM
3 stops49h 55m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$600
Find flight deals from Roanoke to Mississippi
Keep the following information in mind while searching for Roanoke to Mississippi flight deals. Data was last updated July 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (Delta) |
One-way from | $182 (Kiwi.com) |
Cheapflights Fare Finder
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Customize your flight search to find flights from Roanoke to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
Use the filters below to find and compare flights from Roanoke to Mississippi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeJackson
ROA - JAN
ROAJAN
Roanoke
Mon 8/10
11:18 am-2:44 pm
1 stop4h 26m
Jackson-Evers Intl
Mon 8/17
1:00 pm-7:19 pm
1 stop5h 19m
$309
RoanokeMobile
ROA - MOB
ROAMOB
Roanoke
Thu 8/13
2:23 pm-8:36 pm
1 stop7h 13m
Mobile
Tue 8/18
6:27 am-1:53 pm
1 stop6h 26m
$309
RoanokeMobile
ROA - MOB
ROAMOB
Roanoke
Fri 8/14
5:03 pm-8:36 pm
1 stop4h 33m
Mobile
Sun 8/16
4:36 pm-9:54 pm
1 stop4h 18m
$309
Quickest round-trip
RoanokeMemphis
ROA - MEM
ROAMEM
Roanoke
Fri 9/11
6:00 am-9:22 am
1 stop4h 22m
Memphis
Sat 9/12
4:49 pm-9:51 pm
1 stop4h 02m
$335
RoanokeMemphis
ROA - MEM
ROAMEM
Roanoke
Thu 9/3
6:15 am-9:33 am
1 stop4h 18m
Memphis
Sun 9/6
7:00 am-12:25 pm
1 stop4h 25m
$335
RoanokeJackson
ROA - JAN
ROAJAN
Roanoke
Wed 8/5
11:18 am-4:16 pm
1 stop5h 58m
Jackson-Evers Intl
Sat 8/8
5:01 pm-9:38 pm
1 stop3h 37m
$339
RoanokeMemphis
ROA - MEM
ROAMEM
Roanoke
Fri 9/11
6:00 am-9:22 am
1 stop4h 22m
Memphis
Fri 9/11
4:49 pm-9:51 pm
1 stop4h 02m
$377
RoanokeMemphis
ROA - MEM
ROAMEM
Roanoke
Sat 8/22
3:00 pm-11:18 pm
2 stops9h 18m
Memphis
Sun 8/23
9:47 am-5:09 pm
1 stop6h 22m
$379
RoanokeMemphis
ROA - MEM
ROAMEM
Roanoke
Sat 10/31
6:40 am-10:46 am
1 stop5h 06m
Memphis
Tue 11/3
2:37 pm-8:46 pm
1 stop5h 09m
$389
RoanokeMemphis
ROA - MEM
ROAMEM
Roanoke
Tue 8/25
5:50 pm-11:18 pm
1 stop6h 28m
Memphis
Sat 8/29
9:47 am-5:09 pm
1 stop6h 22m
$389
Showing 1-10 of 26 resultsSorted by cheapest first
Best time to book a flight from Roanoke to Mississippi
Have a flexible travel schedule? Discover the best time to fly to Mississippi from Roanoke with our price prediction graph.
ROA-JAN
ROA-MOB
ROA-MEM
ROA-GTR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to Mississippi
ROA-USMS
ROA-JAN
ROA-MOB
ROA-MEM
ROA-GTR
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Mississippi
Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated July 23, 2026.
Read through reviews of airlines operating flights from Roanoke to Mississippi, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Comfort
7.8
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Crew
8.5
Comfort
7.8
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Crew
8.5
Comfort
7.8
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Roanoke to Mississippi
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Complete your trip
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Roanoke and Mississippi flights
Browse other Roanoke and Mississippi flight options. Last updated on July 23, 2026.
Popular flight searches
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Roanoke to Mississippi flights
Consider these flights traveling from Roanoke to Mississippi.
Top 2 airlines flying from Roanoke to Mississippi
Discover the top 2 airlines that operate flights from Roanoke to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$386 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$262 | Average$438 | FlexibilityNo cancel fee | On-timeN/A |