$254+ Cheap flights from St. Louis to Roanoke (STL - ROA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/14. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ROA
Jul 11 — Jul 181
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Roanoke with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Roanoke
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Best
Last-minute
One-way
Cheapest flights from St. Louis to RoanokeExplore the most affordable flight options available from St. Louis to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.
Explore the most affordable flight options available from St. Louis to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:58 pm
STL
- ROA
1 stop4h 27m
Delta
Wed 7/227:59 pm
ROA
- STL
1 stop4h 54m
Delta
Deal found 6/10![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:13 pm
STL
- ROA
1 stop4h 46m
American Airlines
Thu 7/95:00 am
ROA
- STL
1 stop4h 33m
American Airlines
Deal found 6/9![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:05 pm
STL
- ROA
1 stop4h 18m
Delta
Sun 11/17:50 pm
ROA
- STL
1 stop4h 49m
Delta
Deal found 6/10![Delta logo]()
$324
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:14 am
STL
- ROA
1 stop4h 31m
American Airlines
Sat 6/275:00 am
ROA
- STL
1 stop4h 38m
American Airlines
Deal found 6/10![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/29:30 am
STL
- ROA
1 stop6h 39m
United Airlines
Thu 9/106:40 am
ROA
- STL
1 stop6h 17m
United Airlines
Deal found 6/10![United Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:25 pm
STL
- ROA
1 stop4h 45m
American Airlines
Tue 9/85:30 am
ROA
- STL
1 stop6h 22m
American Airlines
Deal found 6/10![American Airlines logo]()
$394
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/269:30 am
STL
- ROA
1 stop6h 39m
United Airlines
Wed 9/25:51 pm
ROA
- STL
1 stop5h 09m
United Airlines
Deal found 6/8![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:20 am
STL
- ROA
1 stop7h 05m
American Airlines
Mon 10/265:00 am
ROA
- STL
1 stop4h 03m
American Airlines
Deal found 6/10![American Airlines logo]()
$479
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:10 pm
STL
- ROA
2 stops9h 17m
Delta
Tue 9/83:25 pm
ROA
- STL
1 stop6h 25m
Delta
Deal found 6/10![Delta logo]()
$507
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/111:00 am
STL
- ROA
1 stop4h 12m
Delta
Sat 9/57:05 am
ROA
- STL
2 stops10h 39m
Delta
Deal found 6/7![Delta logo]()
$512
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/63:57 pm
STL
- ROA
2 stops7h 35m
Delta
Mon 7/137:57 pm
ROA
- STL
1 stop4h 56m
Delta
Deal found 6/7![Delta logo]()
$518
Best flights from St. Louis to RoanokeDiscover carefully curated flight deals from St. Louis to Roanoke that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 11, 2026.
Discover carefully curated flight deals from St. Louis to Roanoke that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 11, 2026.
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:05 pm
STL
- ROA
1 stop4h 18m
Delta
Sun 11/17:50 pm
ROA
- STL
1 stop4h 49m
Delta
Deal found 6/10![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/269:30 am
STL
- ROA
1 stop6h 39m
United Airlines
Wed 9/26:40 am
ROA
- STL
1 stop6h 22m
United Airlines
Deal found 6/7![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:30 pm
STL
- ROA
1 stop4h 26m
United Airlines
Tue 9/156:40 am
ROA
- STL
1 stop6h 17m
United Airlines
Deal found 6/8![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:51 am
STL
- ROA
2 stops11h 40m
Delta
Wed 7/296:00 am
ROA
- STL
1 stop4h 43m
Delta
Deal found 6/7![Delta logo]()
$541
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:23 pm
STL
- ROA
1 stop6h 04m
Delta
Wed 9/26:00 am
ROA
- STL
1 stop4h 20m
Delta
Deal found 6/8![Delta logo]()
$547
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:30 am
STL
- ROA
1 stop6h 41m
United Airlines
Fri 7/245:52 pm
ROA
- STL
1 stop6h 37m
United Airlines
Deal found 6/10![United Airlines logo]()
$599
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:58 pm
STL
- ROA
1 stop4h 27m
Delta
Wed 7/157:05 am
ROA
- STL
2 stops8h 43m
Delta
Deal found 6/9![Delta logo]()
$620
Last-minute flights from St. Louis to RoanokeDiscover last-minute flight deals from St. Louis to Roanoke. Data last updated June 11, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Roanoke. Data last updated June 11, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:14 am
STL
- ROA
1 stop4h 31m
American Airlines
Sat 6/275:00 am
ROA
- STL
1 stop4h 38m
American Airlines
Deal found 6/10![American Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:13 pm
STL
- ROA
1 stop4h 46m
American Airlines
Thu 7/95:00 am
ROA
- STL
1 stop4h 33m
American Airlines
Deal found 6/9![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:59 pm
STL
- ROA
2 stops14h 43m
United Airlines
Thu 7/96:40 am
ROA
- STL
1 stop6h 31m
United Airlines
Deal found 6/9![United Airlines logo]()
$595
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/63:57 pm
STL
- ROA
2 stops7h 35m
Delta
Mon 7/137:57 pm
ROA
- STL
1 stop4h 56m
Delta
Deal found 6/7![Delta logo]()
$518
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:10 am
STL
- ROA
1 stop4h 30m
American Airlines
Wed 7/1511:05 am
ROA
- STL
1 stop7h 16m
American Airlines
Deal found 6/9![American Airlines logo]()
$547
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:58 pm
STL
- ROA
1 stop4h 27m
Delta
Wed 7/227:59 pm
ROA
- STL
1 stop4h 54m
Delta
Deal found 6/10![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:51 am
STL
- ROA
2 stops11h 40m
Delta
Wed 7/296:00 am
ROA
- STL
1 stop4h 43m
Delta
Deal found 6/7![Delta logo]()
$541
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:30 am
STL
- ROA
1 stop6h 41m
United Airlines
Fri 7/245:52 pm
ROA
- STL
1 stop6h 37m
United Airlines
Deal found 6/10![United Airlines logo]()
$599
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:21 am
STL
- ROA
2 stops10h 23m
Delta
Mon 7/277:57 pm
ROA
- STL
1 stop4h 56m
Delta
Deal found 6/10![Delta logo]()
$559
One-way flights from St. Louis to RoanokeSearch for one-way flight options from St. Louis to Roanoke. Find affordable one-way fares based on user searches. Data last updated June 11, 2026.
Search for one-way flight options from St. Louis to Roanoke. Find affordable one-way fares based on user searches. Data last updated June 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:57 pm
STL
- ROA
3 stops43h 59m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$254
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/149:32 am
STL
- ROA
1 stop6h 28m
American Airlines
Deal found 6/7![American Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:10 pm
STL
- ROA
2 stops9h 17m
Delta
Deal found 6/7![Delta logo]()
$313
This deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:43 am
STL
- ROA
1 stop4h 17m
United Airlines
Deal found 6/7![United Airlines logo]()
$553
Find flight deals from St. Louis to Roanoke
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Roanoke (ROA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (Delta) |
One-way from | $254 (Kiwi.com) |
Popular in | March |
Cheapest in | December |
Average price | $328 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
Use the filters below to find and compare flights from St. Louis to Roanoke that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
St. LouisRoanoke
STL - ROA
STLROA
Lambert-St Louis
Wed 10/28
7:05 pm-12:23 am
1 stop4h 18m
Roanoke
Sun 11/1
7:50 pm-11:39 pm
1 stop4h 49m
$324
St. LouisRoanoke
STL - ROA
STLROA
Lambert-St Louis
Wed 8/26
9:30 am-5:09 pm
1 stop6h 39m
Roanoke
Wed 9/2
6:40 am-12:02 pm
1 stop6h 22m
$399
St. LouisRoanoke
STL - ROA
STLROA
Lambert-St Louis
Tue 9/8
5:30 pm-10:56 pm
1 stop4h 26m
Roanoke
Tue 9/15
6:40 am-11:57 am
1 stop6h 17m
$399
St. LouisRoanoke
STL - ROA
STLROA
Lambert-St Louis
Wed 7/22
10:51 am-11:31 pm
2 stops11h 40m
Roanoke
Wed 7/29
6:00 am-9:43 am
1 stop4h 43m
$541
St. LouisRoanoke
STL - ROA
STLROA
Lambert-St Louis
Mon 8/31
5:23 pm-12:27 am
1 stop6h 04m
Roanoke
Wed 9/2
6:00 am-9:20 am
1 stop4h 20m
$547
St. LouisRoanoke
STL - ROA
STLROA
Lambert-St Louis
Wed 7/22
9:30 am-5:11 pm
1 stop6h 41m
Roanoke
Fri 7/24
5:52 pm-11:29 pm
1 stop6h 37m
$599
St. LouisRoanoke
STL - ROA
STLROA
Lambert-St Louis
Mon 7/13
6:58 pm-12:25 am
1 stop4h 27m
Roanoke
Wed 7/15
7:05 am-2:48 pm
2 stops8h 43m
$620
Cheapest one-way
Quickest one-way
St. LouisRoanoke
STL - ROA
STLROA
Lambert-St Louis
Fri 8/14
9:32 am-5:00 pm
1 stop6h 28m
$274
St. LouisRoanoke
STL - ROA
STLROA
Lambert-St Louis
Fri 8/14
2:10 pm-12:27 am
2 stops9h 17m
$313
Sorted by cheapest first
Compare providers for flights from St. Louis to Roanoke
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Roanoke in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Roanoke flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Roanoke flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Roanoke flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Roanoke flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Roanoke flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Roanoke
Have a flexible travel schedule? Discover the best time to fly to Roanoke from St. Louis with our price prediction graph.
STL-ROA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Roanoke
Prices
More
What’s the top layover airport for flights from St. Louis to Roanoke?
Share of 1-stop round-trip flights from St. Louis to Roanoke chosen by Cheapflights users in the past 12 months, using the same layover each way.
Charlotte (CLT) – chosen by Cheapflights users on 67% of 1-stop itineraries from St. Louis to Roanoke on Cheapflights.
What’s the cheapest layover airport for flights from St. Louis to Roanoke?
Average round-trip fare for 1-stop flights from St. Louis to Roanoke, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Chicago (ORD) is the most affordable 1-stop option, with an average round-trip price of $328.
What’s the fastest layover option from St. Louis to Roanoke?
Shortest average travel time for 1-stop one-way flights from St. Louis to Roanoke, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Chicago (ORD) have the shortest average one-way travel time for 1-stop routes: 4h 29m.
Which airport typically offers the quickest layover for flights from St. Louis to Roanoke?
Average layover duration for 1-stop one-way flights from St. Louis to Roanoke, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Charlotte (CLT) offer the fastest connection on this route, with an average layover time of 1h 37m.
Reviews of airlines servicing Roanoke
Get insights into the airlines that provide service to Roanoke. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Roanoke. Reviews last updated June 11, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from St. Louis to Roanoke to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Food
7.2
Overall
7.9
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Overall
7.9
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Overall
7.9
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Overall
7.9
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Roanoke?
Book flights to Roanoke if you plan to visit one of these locationsSalem
Radford
Blacksburg
Christiansburg
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St. Louis and Roanoke flights
Browse other St. Louis and Roanoke flight options. Last updated on June 11, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on June 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Roanoke
Explore flights to Roanoke departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 11, 2026.
Top 3 airlines flying from St. Louis to Roanoke
Discover the top 3 airlines that operate flights from St. Louis to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$196 | Average$394 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$351 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$259 | Average$457 | FlexibilityNo cancel fee | On-time69% |