What is the cheapest month to book a flight from Panama to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Panama to St. Louis (average of $311). Flying from Panama to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest month to fly from Panama to St. Louis?

March is one of the best times of the year to fly to St. Louis from Panama. Prices for March average $553 per person but you can even find prices for as low as $386. The most expensive prices can be found in the month of January. Opting for a March flight can save you 10% on your journey compared to booking in January

What airport do you fly into for flights to St. Louis from Panama?

If you book a flight to St. Louis from Panama, you will be flying to Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis.

Can I find deals for flights from Panama to St. Louis that include hotel bookings?

Yes. In addition to deals on Panama to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to St. Louis.

Can I find deals for business class flights from Panama to St. Louis?

Yes. Cheapflights offers flight deals from Panama to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$1,534+ Flights from Panama to St. Louis - Compare & Save Big

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Cheap flight deals from Panama to St. Louis

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$451 (American Airlines)
One-way from	$247 (Delta)
Popular in	January
Cheapest in	March
Average price	$535

Provider with most accurate pricing for Panama City Tocumen Intl-Lambert-St Louis flight deals.

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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Lambert-St Louis flights.

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From Panama to Lambert-St Louis

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One-way flight from Panama to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 5% potential increase in price ($35 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).

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Average for round-trip flights in May 2025

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Find flight deals from Panama to St. Louis

Cheapest flights from Panama to St. Louis
Explore the most affordable flight options available from Panama to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Wed 8/273:40 pmPTY - STL

1 stop8h 19mAmerican Airlines

Fri 9/55:31 amSTL - PTY

1 stop6h 54mAmerican Airlines

Deal found 4/29

$451

Sat 6/143:30 pmPTY - STL

1 stop25h 23mUnited Airlines

Sat 6/218:25 amSTL - PTY

1 stop10h 12mUnited Airlines

Deal found 4/30

$558

Tue 5/62:20 pmPTY - STL

1 stop9h 16mDelta

Tue 5/136:00 amSTL - PTY

1 stop6h 48mDelta

Deal found 4/29

$607

Thu 5/223:20 amPTY - STL

2 stops20h 32mMultiple Airlines

Sat 5/2410:10 amSTL - PTY

1 stop10h 09mMultiple Airlines

Deal found 4/29

$860

Wed 5/73:20 amPTY - STL

2 stops16h 03mAvianca

Sun 5/119:40 amSTL - PTY

2 stops14h 30mAvianca

Deal found 4/29

$3,655

Mon 5/2610:29 pmPTY - STL

1 stop11h 27mCopa Airlines

Mon 6/98:10 amSTL - PTY

1 stop12h 25mCopa Airlines

Deal found 4/29

$3,978

Best flights from Panama to St. Louis
Discover carefully curated flight deals from Panama to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2025.

Wed 8/273:40 pmPTY - STL

1 stop8h 19mAmerican Airlines

Fri 9/55:31 amSTL - PTY

1 stop6h 54mAmerican Airlines

Deal found 4/29

$451

Sat 6/143:30 pmPTY - STL

1 stop25h 23mUnited Airlines

Sat 6/218:25 amSTL - PTY

1 stop10h 12mUnited Airlines

Deal found 4/30

$558

Thu 5/223:20 amPTY - STL

2 stops20h 32mMultiple Airlines

Sat 5/2410:10 amSTL - PTY

1 stop10h 09mMultiple Airlines

Deal found 4/29

$860

Wed 5/282:13 pmPTY - STL

1 stop9h 25mDelta

Mon 6/96:00 amSTL - PTY

1 stop7h 08mDelta

Deal found 4/29

$2,096

Tue 8/263:20 amPTY - STL

2 stops30h 42mAvianca

Fri 9/58:15 amSTL - PTY

2 stops32h 15mAvianca

Deal found 4/29

$3,777

Mon 5/2610:29 pmPTY - STL

1 stop11h 27mCopa Airlines

Mon 6/98:10 amSTL - PTY

1 stop12h 25mCopa Airlines

Deal found 4/29

$3,978

Last-minute flights from Panama to St. Louis
Discover last-minute flight deals from Panama to St. Louis. Data last updated May 1, 2025 and is based on user searches.

Tue 5/62:20 pmPTY - STL

1 stop9h 16mDelta

Tue 5/136:00 amSTL - PTY

1 stop6h 48mDelta

Deal found 4/29

$607

Wed 5/73:20 amPTY - STL

2 stops16h 03mAvianca

Sun 5/119:40 amSTL - PTY

2 stops14h 30mAvianca

Deal found 4/29

$3,655

Thu 5/87:55 amPTY - STL

1 stop14h 08mUnited Airlines

Sun 5/118:30 amSTL - PTY

1 stop29h 44mUnited Airlines

Deal found 4/29

$635

Mon 5/197:55 amPTY - STL

1 stop12h 37mUnited Airlines

Sat 6/710:53 amSTL - PTY

1 stop27h 21mUnited Airlines

Deal found 4/29

$600

Mon 5/191:20 pmPTY - STL

1 stop28h 09mAmerican Airlines

Sat 6/75:30 amSTL - PTY

2 stops8h 55mAmerican Airlines

Deal found 4/29

$615

Thu 5/223:20 amPTY - STL

2 stops20h 32mMultiple Airlines

Sat 5/2410:10 amSTL - PTY

1 stop10h 09mMultiple Airlines

Deal found 4/29

$860

Mon 5/2610:29 pmPTY - STL

1 stop11h 27mCopa Airlines

Mon 6/98:10 amSTL - PTY

1 stop12h 25mCopa Airlines

Deal found 4/29

$3,978

One-way flights from Panama to St. Louis
Search for one-way flight options from Panama to St. Louis. Find affordable one-way fares based on user searches. Data last updated May 1, 2025.

Sun 6/88:10 amPTY - STL

1 stop8h 15mDelta

Deal found 4/30

$247

Sun 6/83:20 pmPTY - STL

2 stops20h 53mAmerican Airlines

Deal found 4/30

$284

Sun 6/86:34 pmPTY - STL

3 stops29h 03mMultiple Airlines

Deal found 4/30

$393

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Wed 8/27

3:40 pm-11:59 pm

1 stop8h 19m

Lambert-St Louis

Fri 9/5

5:31 am-12:25 pm

1 stop6h 54m

$451

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Sat 6/14

3:30 pm-4:53 pm

1 stop25h 23m

Lambert-St Louis

Sat 6/21

8:25 am-6:37 pm

1 stop10h 12m

$558

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Thu 5/22

3:20 am-11:52 pm

2 stops20h 32m

Lambert-St Louis

Sat 5/24

10:10 am-8:19 pm

1 stop10h 09m

$860

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Wed 5/28

2:13 pm-11:38 pm

1 stop9h 25m

Lambert-St Louis

Mon 6/9

6:00 am-1:08 pm

1 stop7h 08m

$2,096

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Tue 8/26

3:20 am-10:02 am

2 stops30h 42m

Lambert-St Louis

Fri 9/5

8:15 am-4:30 pm

2 stops32h 15m

$3,777

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Mon 5/26

10:29 pm-9:56 am

1 stop11h 27m

Lambert-St Louis

Mon 6/9

8:10 am-8:35 pm

1 stop12h 25m

$3,978

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Sun 6/8

8:10 am-4:25 pm

1 stop8h 15m

$247

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Sun 6/8

3:20 pm-12:13 pm

2 stops20h 53m

$284

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Sun 6/8

6:34 pm-11:37 pm

3 stops29h 03m

$393

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Best time to book a flight from Panama to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Panama with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to St. Louis

What is the cheapest time of day to fly from PA to STL?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to St. Louis as you normally would.

Rainfall in St. Louis by month

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Get a feel of what it's like to fly with Delta, Copa Airlines and United Airlines from Panama to St. Louis by reading reviews from past customers. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

7,934 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Copa Airlines

7.5

Good

1,415 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines

7.4

Good

8,696 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Avianca

6.7

Okay

2,317 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What airport do you fly into for flights to St. Louis from Panama?
If you book a flight to St. Louis from Panama, you will be flying to Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis.
Can I find deals for flights from Panama to St. Louis that include hotel bookings?
Yes. In addition to deals on Panama to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to St. Louis.
Can I find deals for business class flights from Panama to St. Louis?
Yes. Cheapflights offers flight deals from Panama to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Panama to St. Louis (average of $311). Flying from Panama to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Fenton

Maryland Heights

Fairview Heights

Collinsville

Wentzville

Eureka

St. Peters

Festus

Glencoe

Alton

Farmington

O'Fallon

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Panama to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$252	Average$563	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$354	Average$558	FlexibilityNo cancel fee	On-timeN/A

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$247+ Cheap flights from Panama to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/8. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Panama to St. Louis

Keep the following information in mind while searching for Panama to St. Louis flight deals. Data was last updated May 1, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Panama to St. Louis

Cheapest flights from Panama to St. LouisExplore the most affordable flight options available from Panama to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Explore the most affordable flight options available from Panama to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama to St. Louis that are best for you.

Best time to book a flight from Panama to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Panama with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Panama to St. Louis

What is the cheapest time of day to fly from PA to STL?

Find hourly flight availability from Panama to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

Reviews of airlines servicing St. Louis

Related info for your journey

Find useful and relevant information for your journey from Panama to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to St. Louis from Panama?

Can I find deals for flights from Panama to St. Louis that include hotel bookings?

How can I find direct flights from Panama to St. Louis?

Can I find deals for business class flights from Panama to St. Louis?

What is the cheapest month to book a flight from Panama to St. Louis?

Traveling to a place near Panama?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Panama to St. Louis

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Cheapest flights from Panama to St. Louis
Explore the most affordable flight options available from Panama to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.