$141+ Cheap flights from Maine to St. Louis (STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — STL
Nov 10 — Nov 171
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Maine to St. Louis
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Cheapest flights from Maine to St. LouisExplore the most affordable flight options available from Maine to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 11, 2026.
Explore the most affordable flight options available from Maine to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 11, 2026.
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:50 pm -
1 stop7h 32m
Sat 11/77:05 am -
1 stop6h 19m
Deal found 10/8![American Airlines logo]()
$281
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:49 am -
2 stops7h 54m
Sat 11/78:30 am -
1 stop4h 46m
Deal found 10/8![United Airlines logo]()
$286
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:25 am -
2 stops10h 00m
Sat 11/75:45 am -
2 stops8h 00m
Deal found 10/8![Southwest logo]()
$297
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/174:50 pm -
1 stop4h 39m
Wed 11/252:31 pm -
1 stop8h 00m
Deal found 10/8![Delta logo]()
$310
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:55 am -
1 stop5h 48m
Thu 10/292:25 pm -
1 stop7h 36m
Deal found 10/8![Delta logo]()
$311
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:40 am -
1 stop6h 55m
Thu 10/292:30 pm -
2 stops8h 25m
Deal found 10/8![Southwest logo]()
$316
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop6h 15m
Fri 11/135:30 pm -
1 stop5h 01m
Deal found 10/7![Delta logo]()
$320
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:30 am -
2 stops7h 40m
Thu 11/266:00 am -
2 stops7h 27m
Deal found 10/6![United Airlines logo]()
$321
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:25 pm -
1 stop7h 50m
Fri 11/132:45 pm -
2 stops8h 10m
Deal found 10/7![Southwest logo]()
$325
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1711:39 am -
1 stop5h 15m
Sun 11/225:30 pm -
1 stop5h 01m
Deal found 10/8![Delta logo]()
$335
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:16 pm -
1 stop8h 30m
Sun 11/16:00 am -
1 stop4h 55m
Deal found 10/6![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:24 pm -
1 stop6h 14m
Mon 11/233:49 pm -
1 stop7h 23m
Deal found 10/8![American Airlines logo]()
$356
Best flights from Maine to St. LouisDiscover carefully curated flight deals from Maine to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 11, 2026.
Discover carefully curated flight deals from Maine to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 11, 2026.
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:29 am -
1 stop8h 14m
Thu 11/268:30 am -
1 stop4h 56m
Deal found 10/6![United Airlines logo]()
$281
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/121:00 pm -
1 stop7h 15m
Mon 12/146:35 am -
1 stop4h 35m
Deal found 10/7![Southwest logo]()
$281
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop6h 15m
Fri 11/135:30 pm -
1 stop5h 01m
Deal found 10/7![Delta logo]()
$320
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/204:15 pm -
1 stop6h 31m
Sun 11/2211:14 am -
2 stops11h 04m
Deal found 10/6![American Airlines logo]()
$518
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/123:41 pm -
1 stop7h 34m
Mon 12/146:30 am -
2 stops7h 07m
Deal found 10/7![United Airlines logo]()
$286
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:20 am -
2 stops6h 40m
Thu 10/295:25 am -
2 stops6h 00m
Deal found 10/8![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:30 am -
2 stops7h 40m
Fri 11/277:30 am -
1 stop5h 46m
Deal found 10/6![United Airlines logo]()
$325
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:13 am -
1 stop7h 35m
Sat 11/218:00 am -
1 stop26h 20m
Deal found 10/8![Delta logo]()
$473
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/23:14 pm -
1 stop7h 35m
Wed 2/36:06 am -
2 stops7h 27m
Deal found 10/6![United Airlines logo]()
$396
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:47 am -
1 stop6h 47m
Sun 11/158:00 am -
1 stop5h 27m
Deal found 10/10![United Airlines logo]()
$413
This Delta deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:19 am -
1 stop7h 28m
Sat 11/76:00 am -
2 stops8h 30m
Deal found 10/6![Delta logo]()
$567
This Mytrip deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/243:37 pm -
2 stops33h 22m
Tue 12/16:04 am -
2 stops27h 37m
Deal found 10/10![Multiple Airlines logo]()
$1,560
This Delta deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:00 pm -
2 stops10h 12m
Sun 11/17:00 am -
2 stops8h 22m
Deal found 10/6![Delta logo]()
$652
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:00 pm -
2 stops9h 29m
Mon 11/2312:28 pm -
2 stops9h 57m
Deal found 10/8![Delta logo]()
$669
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:43 pm -
1 stop7h 48m
Wed 10/286:09 am -
1 stop27h 10m
Deal found 10/8![United Airlines logo]()
$661
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2011:00 am -
2 stops11h 40m
Sun 11/228:50 am -
2 stops24h 29m
Deal found 10/6![United Airlines logo]()
$709
Last-minute flights from Maine to St. LouisDiscover last-minute flight deals from Maine to St. Louis. Data last updated October 11, 2026 and is based on user searches.
Discover last-minute flight deals from Maine to St. Louis. Data last updated October 11, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:55 am -
1 stop5h 48m
Thu 10/292:25 pm -
1 stop7h 36m
Deal found 10/8![Delta logo]()
$311
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:40 am -
1 stop6h 55m
Thu 10/292:30 pm -
2 stops8h 25m
Deal found 10/8![Southwest logo]()
$316
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:16 pm -
1 stop8h 30m
Sun 11/16:00 am -
1 stop4h 55m
Deal found 10/6![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:50 pm -
1 stop7h 32m
Sat 11/77:05 am -
1 stop6h 19m
Deal found 10/8![American Airlines logo]()
$281
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:49 am -
2 stops7h 54m
Sat 11/78:30 am -
1 stop4h 46m
Deal found 10/8![United Airlines logo]()
$286
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:25 am -
2 stops10h 00m
Sat 11/75:45 am -
2 stops8h 00m
Deal found 10/8![Southwest logo]()
$297
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop6h 15m
Fri 11/135:30 pm -
1 stop5h 01m
Deal found 10/7![Delta logo]()
$320
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:25 pm -
1 stop7h 50m
Fri 11/132:45 pm -
2 stops8h 10m
Deal found 10/7![Southwest logo]()
$325
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/174:50 pm -
1 stop4h 39m
Wed 11/252:31 pm -
1 stop8h 00m
Deal found 10/8![Delta logo]()
$310
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1711:39 am -
1 stop5h 15m
Sun 11/225:30 pm -
1 stop5h 01m
Deal found 10/8![Delta logo]()
$335
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:24 pm -
1 stop6h 14m
Mon 11/233:49 pm -
1 stop7h 23m
Deal found 10/8![American Airlines logo]()
$356
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:30 am -
2 stops7h 40m
Thu 11/266:00 am -
2 stops7h 27m
Deal found 10/6![United Airlines logo]()
$321
One-way flights from Maine to St. LouisSearch for one-way flight options from Maine to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 11, 2026.
Search for one-way flight options from Maine to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 11, 2026.
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:40 am -
1 stop6h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Southwest logo]()
$141
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:30 am -
2 stops7h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![United Airlines logo]()
$146
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/310:25 am -
2 stops10h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Southwest logo]()
$152
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:08 pm -
1 stop7h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![United Airlines logo]()
$170
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:08 pm -
1 stop5h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![United Airlines logo]()
$171
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:45 pm -
1 stop8h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![American Airlines logo]()
$178
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:30 am -
1 stop6h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![American Airlines logo]()
$180
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:30 am -
2 stops7h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![United Airlines logo]()
$185
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/233:41 pm -
1 stop7h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![United Airlines logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:09 pm -
3 stops49h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Multiple Airlines logo]()
$197
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/255:30 am -
1 stop5h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![American Airlines logo]()
$209
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/204:15 pm -
1 stop6h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![American Airlines logo]()
$319
Find flight deals from Maine to St. Louis
Keep the following information in mind while searching for Maine to St. Louis flight deals. Data was last updated October 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $281 (American Airlines) |
One-way from | $141 (Southwest) |
Popular in | April |
Cheapest in | March |
Average price | $426 |
Cheapflights Fare Finder
Customize your flight search to find flights from Maine to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 11, 2026.
Use the filters below to find and compare flights from Maine to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Mon 11/23
3:41 pm-9:52 pm
1 stop7h 11m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$141
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Tue 11/3
10:25 am-7:25 pm
2 stops10h 00m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$152
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Sat 11/21
2:05 pm-9:34 pm
1 stop8h 29m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$170
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Thu 11/12
5:08 pm-11:24 pm
1 stop7h 16m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$170
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Fri 12/25
3:25 pm-10:10 pm
1 stop7h 45m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$170
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Thu 11/5
3:41 pm-9:52 pm
1 stop7h 11m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$171
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Fri 11/20
6:00 am-1:23 pm
1 stop8h 23m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$219
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Mon 11/23
8:29 am-3:43 pm
1 stop8h 14m
Lambert-St Louis
Thu 11/26
8:30 am-2:26 pm
1 stop4h 56m
$281
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Sat 12/12
1:00 pm-7:15 pm
1 stop7h 15m
Lambert-St Louis
Mon 12/14
6:35 am-12:10 pm
1 stop4h 35m
$281
PortlandSt. Louis
PWM Portland - STL Lambert-St Louis
PWMSTL
Portland
Sat 12/12
3:41 pm-10:15 pm
1 stop7h 34m
Lambert-St Louis
Mon 12/14
6:30 am-2:37 pm
2 stops7h 07m
$286
Showing 1-10 of 30 resultsSorted by cheapest first
Best time to book a flight from Maine to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Maine with our price prediction graph.
PWM-STL
BGR-STL
AUG-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Maine to St. Louis
USME-STL
PWM-STL
BGR-STL
AUG-STL
What is the cheapest month to book a flight from Maine to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Maine to St. Louis (average of $350). Flying from Maine to St. Louis in December is currently the most expensive (average of $782). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Maine to St. Louis?
Airfare is below average for this route at the moment.
Maine to St. Louis flights typically cost between $338 and $546 in November.The cheapest round-trip price found within the last 5 days was $281 on American Airlines (Nov 4-Nov 7).
Related info for your journey
Find useful and relevant information for your journey from Maine to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Maryland Heights
Chesterfield
Collinsville
Edwardsville
Glencoe
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Maine to St. Louis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Maine to St. Louis by cabin class
Find flights from Maine to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Maine and St. Louis flights
Browse other Maine and St. Louis flight options. Last updated on October 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 11, 2026.
Maine to St. Louis flights
Consider these flights traveling from Maine to St. Louis.
Top 4 airlines flying from Maine to St. Louis
Discover the top 4 airlines that operate flights from Maine to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$254 | Average$422 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$278 | Average$415 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$288 | Average$440 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$348 | Average$549 | FlexibilityNo cancel fee | On-time63% |