How popular is this Jacksonville to St. Louis flight route?

The Jacksonville to Lambert-St Louis flight path was viewed by 18 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

How long is the flight from Jacksonville to St. Louis?

Delta can get you from Jacksonville to St. Louis in just under 5h 32m. Your travel time can differ by up to . There are 753 mi between Jacksonville and St. Louis.

What are the cheapest airlines flying from Jacksonville to St. Louis round-trip?

Delta, at $176, was found to be the cheapest airline from Jacksonville to St. Louis.Alternate airlines to your destination round-trip include Southwest and American Airlines. Delta is 44% cheaper than the average price of flights available within the next 90 days to this destination.

What are the cheapest airlines to fly from Jacksonville to St. Louis one-way?

The cheapest airlines for a one-way flight from Jacksonville to St. Louis are Southwest ($101), Delta ($109), and American Airlines ($109).

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the cheapest flights from Jacksonville to St. Louis?

On average you can expect to pay $335 for a flight from Jacksonville to St. Louis. The cheapest flight overall is $168 while the most popular route, (Jacksonville - Lambert-St Louis) is currently priced at $295.

What are the most popular airlines that fly from Jacksonville to St. Louis?

Southwest, Delta and American Airlines are the most popular airlines when flying from Jacksonville to St. Louis.

Most accurate provider : When it comes to deals on Jacksonville-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Jacksonville-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Jacksonville-St. Louis flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Jacksonville-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Jacksonville-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airports do I use to fly from Jacksonville to St. Louis?

If you book a flight from Jacksonville to St. Louis, you will be flying from Jacksonville to Lambert-St Louis. Flights to Lambert-St Louis (STL) from Jacksonville (JAX) take 2h 15m for a nonstop flight. There is 1 flight from Jacksonville to St. Louis per day from 3 airlines.

Can I find deals for flights from Jacksonville to St. Louis that include hotel bookings?

Yes. In addition to deals on Jacksonville to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Jacksonville to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to St. Louis.

Can I find deals for business class flights from Jacksonville to St. Louis?

Yes. Cheapflights offers flight deals from Jacksonville to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$84+ Flights from Jacksonville to St. Louis

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheapflights Tip: The best prices from Jacksonville to Lambert-St Louis are usually found in July or August, booked 29 days in advance, depart on a Tuesday or Friday and return on a Friday

Cheap flight deals from Jacksonville to St. Louis

Cheapest flights from Jacksonville to St. Louis
Explore the most affordable flight options available from Jacksonville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Sat 12/2712:21 pmJAX - STL

1 stop8h 05mAmerican Airlines

Sat 1/36:35 pmSTL - JAX

1 stop4h 13mAmerican Airlines

Deal found 12/26

$351

Tue 12/304:55 pmJAX - STL

1 stop6h 00mUnited Airlines

Thu 1/18:05 amSTL - JAX

1 stop5h 03mUnited Airlines

Deal found 12/26

$367

Wed 12/319:33 amJAX - STL

2 stops7h 50mAmerican Airlines

Thu 1/19:08 amSTL - JAX

1 stop7h 49mAmerican Airlines

Deal found 12/27

$372

Wed 12/311:30 pmJAX - STL

2 stops10h 13mUnited Airlines

Thu 1/18:05 amSTL - JAX

2 stops11h 05mUnited Airlines

Deal found 12/26

$447

Sat 12/279:25 pmJAX - STL

1 stop3h 50mSouthwest

Sat 1/31:00 pmSTL - JAX

Nonstop1h 55mSouthwest

Deal found 12/26

$527

Sun 12/284:55 pmJAX - STL

1 stop6h 00mUnited Airlines

Wed 12/311:05 pmSTL - JAX

2 stops8h 06mUnited Airlines

Deal found 12/27

$645

Tue 12/307:50 amJAX - STL

Nonstop2h 20mSouthwest

Thu 1/16:05 amSTL - JAX

1 stop6h 25mSouthwest

Deal found 12/26

$698

Best flights from Jacksonville to St. Louis
Discover carefully curated flight deals from Jacksonville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

Tue 2/247:04 pmJAX - STL

1 stop5h 32mDelta

Thu 2/266:10 amSTL - JAX

1 stop7h 00mDelta

Deal found 12/27

$295

Thu 1/294:38 pmJAX - STL

1 stop7h 20mUnited Airlines

Mon 2/23:11 pmSTL - JAX

1 stop5h 33mUnited Airlines

Deal found 12/26

$301

Thu 2/265:30 amJAX - STL

1 stop4h 36mDelta

Tue 3/36:00 amSTL - JAX

1 stop5h 17mDelta

Deal found 12/27

$295

Sat 1/242:40 pmJAX - STL

1 stop7h 33mUnited Airlines

Sat 1/3111:20 amSTL - JAX

2 stops9h 27mUnited Airlines

Deal found 12/27

$306

Mon 2/235:58 pmJAX - STL

1 stop3h 43mDelta

Tue 3/35:00 pmSTL - JAX

1 stop4h 58mDelta

Deal found 12/27

$295

Tue 2/246:30 amJAX - STL

1 stop5h 32mDelta

Sat 2/2810:11 amSTL - JAX

1 stop3h 38mDelta

Deal found 12/27

$295

Thu 2/265:30 amJAX - STL

1 stop4h 36mDelta

Mon 3/210:13 amSTL - JAX

1 stop3h 43mDelta

Deal found 12/27

$301

Thu 2/265:30 amJAX - STL

1 stop4h 36mDelta

Thu 2/266:47 pmSTL - JAX

1 stop4h 14mDelta

Deal found 12/27

$301

Mon 2/237:04 pmJAX - STL

1 stop5h 32mDelta

Thu 2/266:47 pmSTL - JAX

1 stop4h 14mDelta

Deal found 12/27

$301

Tue 2/2411:28 amJAX - STL

1 stop4h 19mDelta

Fri 2/273:47 pmSTL - JAX

1 stop5h 05mDelta

Deal found 12/27

$303

Fri 2/2711:28 amJAX - STL

1 stop4h 19mDelta

Wed 3/41:13 pmSTL - JAX

1 stop7h 50mDelta

Deal found 12/27

$303

Thu 2/265:30 amJAX - STL

1 stop6h 32mDelta

Sun 3/16:56 pmSTL - JAX

1 stop4h 05mDelta

Deal found 12/27

$309

Last-minute flights from Jacksonville to St. Louis
Discover last-minute flight deals from Jacksonville to St. Louis. Data last updated December 28, 2025 and is based on user searches.

Sat 12/2712:21 pmJAX - STL

1 stop8h 05mAmerican Airlines

Sat 1/36:35 pmSTL - JAX

1 stop4h 13mAmerican Airlines

Deal found 12/26

$351

Tue 1/135:30 amJAX - STL

1 stop4h 23mDelta

Sun 1/187:10 amSTL - JAX

1 stop4h 01mDelta

Deal found 12/26

$344

Sat 1/173:28 pmJAX - STL

1 stop4h 59mDelta

Sun 1/186:10 amSTL - JAX

1 stop6h 26mDelta

Deal found 12/26

$319

Sat 1/1711:40 amJAX - STL

Nonstop2h 20mSouthwest

Sun 1/182:35 pmSTL - JAX

1 stop6h 20mSouthwest

Deal found 12/26

$324

Sat 1/176:35 amJAX - STL

2 stops8h 53mUnited Airlines

Sun 1/186:30 amSTL - JAX

1 stop6h 39mUnited Airlines

Deal found 12/26

$358

Sat 1/242:40 pmJAX - STL

1 stop7h 33mUnited Airlines

Sat 1/3111:20 amSTL - JAX

2 stops9h 27mUnited Airlines

Deal found 12/27

$306

Mon 1/265:30 amJAX - STL

1 stop4h 23mDelta

Mon 2/29:45 amSTL - JAX

1 stop6h 09mDelta

Deal found 12/27

$301

Mon 1/265:50 amJAX - STL

1 stop9h 05mSouthwest

Mon 2/211:30 amSTL - JAX

2 stops8h 45mSouthwest

Deal found 12/27

$316

Fri 1/307:18 pmJAX - STL

1 stop12h 33mFrontier

Mon 2/29:45 pmSTL - JAX

2 stops43h 48mFrontier

Deal found 12/26

$277

Fri 1/303:15 pmJAX - STL

1 stop6h 22mDelta

Mon 2/27:10 amSTL - JAX

1 stop3h 58mDelta

Deal found 12/26

$309

One-way flights from Jacksonville to St. Louis
Search for one-way flight options from Jacksonville to St. Louis. Find affordable one-way fares based on user searches. Data last updated December 28, 2025.

Fri 1/168:17 pmJAX - STL

1 stop11h 34mFrontier

Deal found 12/26

$84

Fri 1/237:18 pmJAX - STL

1 stop12h 33mFrontier

Deal found 12/27

$85

Wed 3/258:18 pmJAX - STL

1 stop15h 13mFrontier

Deal found 12/27

$94

Mon 3/235:58 pmJAX - STL

1 stop17h 33mFrontier

Deal found 12/27

$102

Thu 2/59:04 pmJAX - STL

2 stops39h 07mMultiple Airlines

Deal found 12/27

$106

Fri 1/307:18 pmJAX - STL

1 stop12h 33mFrontier

Deal found 12/26

$109

Mon 1/2611:25 amJAX - STL

2 stops37h 08mMultiple Airlines

Deal found 12/27

$110

Thu 1/229:04 pmJAX - STL

2 stops27h 29mFrontier

Deal found 12/26

$113

Find flight deals from Jacksonville to St. Louis

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$199 (Kiwi.com)
One-way from	$84 (Trip.com)
Popular in	March
Cheapest in	July
Average price	$389
Good round-trip deal	$365 or less
Good one-way deal	$242 or less

Provider with most accurate pricing for Jacksonville-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Jacksonville-Lambert-St Louis flights.

Search Deals

From Jacksonville to Lambert-St Louis

Search Deals

One-way flight from Jacksonville to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 6% potential increase in price ($23 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Jacksonville to Lambert-St Louis.

Search Deals

Price to beat on a one-way flight from Jacksonville to Lambert-St Louis.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Jacksonville to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Tue 2/24

7:04 pm-11:36 pm

1 stop5h 32m

Lambert-St Louis

Thu 2/26

6:10 am-2:10 pm

1 stop7h 00m

$295

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Thu 2/26

5:30 am-9:06 am

1 stop4h 36m

Lambert-St Louis

Tue 3/3

6:00 am-12:17 pm

1 stop5h 17m

$295

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Mon 2/23

5:58 pm-8:41 pm

1 stop3h 43m

Lambert-St Louis

Tue 3/3

5:00 pm-10:58 pm

1 stop4h 58m

$295

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Tue 2/24

6:30 am-11:02 am

1 stop5h 32m

Lambert-St Louis

Sat 2/28

10:11 am-2:49 pm

1 stop3h 38m

$295

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Thu 1/29

4:38 pm-10:58 pm

1 stop7h 20m

Lambert-St Louis

Mon 2/2

3:11 pm-9:44 pm

1 stop5h 33m

$301

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Thu 2/26

5:30 am-9:06 am

1 stop4h 36m

Lambert-St Louis

Mon 3/2

10:13 am-2:56 pm

1 stop3h 43m

$301

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Thu 2/26

5:30 am-9:06 am

1 stop4h 36m

Lambert-St Louis

Thu 2/26

6:47 pm-12:01 am

1 stop4h 14m

$301

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Mon 2/23

7:04 pm-11:36 pm

1 stop5h 32m

Lambert-St Louis

Thu 2/26

6:47 pm-12:01 am

1 stop4h 14m

$301

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Tue 2/24

11:28 am-2:47 pm

1 stop4h 19m

Lambert-St Louis

Fri 2/27

3:47 pm-9:52 pm

1 stop5h 05m

$303

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Fri 2/27

11:28 am-2:47 pm

1 stop4h 19m

Lambert-St Louis

Wed 3/4

1:13 pm-10:03 pm

1 stop7h 50m

$303

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Showing 1-10 of 24 results

Compare providers for flights from Jacksonville to St. Louis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Jacksonville to St. Louis in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Jacksonville-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Jacksonville-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Jacksonville-St. Louis flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Jacksonville-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Jacksonville-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Jacksonville to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Jacksonville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to St. Louis

How far ahead should I book a flight from Jacksonville to St. Louis?

The best time to book flights from Jacksonville to St. Louis is 29 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Jacksonville to St. Louis?

Currently, April is the cheapest month in which you can book a flight from Jacksonville to St. Louis (average of $139). Flying from Jacksonville to St. Louis in November is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from JAX to STL?

When flying from Jacksonville to St. Louis, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 17% versus a flight at noon.

What is the cheapest day to fly from Jacksonville to St. Louis?

Travelers seeking maximum savings on their Jacksonville to St. Louis flight should consider departing on Friday afternoons when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

The best insider tips for Jacksonville to St. Louis flights

Cheapflights partnered with top experts to bring you the best recommendations for your Jacksonville to St. Louis trip

Airports

JAX

JAX offers quick screening times at TSA and easy check-in, making it convenient for early morning departures.

STL

Use the MetroLink light rail for a convenient and economical way to reach downtown St. Louis from STL.

Our travel experts

Matt Meltzer

Expert on JAX

Taryn White

Expert on STL

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Jacksonville to St. Louis, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,256 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,019 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,073 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

What airports do I use to fly from Jacksonville to St. Louis?
If you book a flight from Jacksonville to St. Louis, you will be flying from Jacksonville to Lambert-St Louis. Flights to Lambert-St Louis (STL) from Jacksonville (JAX) take 2h 15m for a nonstop flight. There is 1 flight from Jacksonville to St. Louis per day from 3 airlines.
How popular is this Jacksonville to St. Louis flight route?
The Jacksonville to Lambert-St Louis flight path was viewed by 18 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Jacksonville to St. Louis?
Delta can get you from Jacksonville to St. Louis in just under 5h 32m. Your travel time can differ by up to . There are 753 mi between Jacksonville and St. Louis.
What are the cheapest airlines flying from Jacksonville to St. Louis round-trip?
Delta, at $176, was found to be the cheapest airline from Jacksonville to St. Louis.Alternate airlines to your destination round-trip include Southwest and American Airlines. Delta is 44% cheaper than the average price of flights available within the next 90 days to this destination.
What are the cheapest airlines to fly from Jacksonville to St. Louis one-way?
The cheapest airlines for a one-way flight from Jacksonville to St. Louis are Southwest ($101), Delta ($109), and American Airlines ($109).
What are the cheapest flights from Jacksonville to St. Louis?
On average you can expect to pay $335 for a flight from Jacksonville to St. Louis. The cheapest flight overall is $168 while the most popular route, (Jacksonville - Lambert-St Louis) is currently priced at $295.
Can I find deals for flights from Jacksonville to St. Louis that include hotel bookings?
Yes. In addition to deals on Jacksonville to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Jacksonville to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to St. Louis.
Can I find deals for business class flights from Jacksonville to St. Louis?
Yes. Cheapflights offers flight deals from Jacksonville to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Jacksonville to St. Louis?
Currently, April is the cheapest month in which you can book a flight from Jacksonville to St. Louis (average of $139). Flying from Jacksonville to St. Louis in November is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Edwardsville

O'Fallon

Swansea

Fairview Heights

Maryland Heights

Collinsville

Eureka

Glencoe

Chesterfield

Alton

Farmington

Festus

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Top 3 airlines flying from Jacksonville to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$194	Average$269	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$214	Average$308	FlexibilityNo cancel fee	On-time63%
American Airlines	Cheapest$218	Average$305	FlexibilityNo cancel fee	On-time71%

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$84+ Cheap flights from Jacksonville to St. Louis (JAX - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Jacksonville to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Jacksonville to Lambert-St Louis are usually found in July or August, booked 29 days in advance, depart on a Tuesday or Friday and return on a Friday

Cheap flight deals from Jacksonville to St. Louis

Cheapest flights from Jacksonville to St. LouisExplore the most affordable flight options available from Jacksonville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Explore the most affordable flight options available from Jacksonville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Find flight deals from Jacksonville to St. Louis

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Jacksonville to St. Louis that are best for you.

Compare providers for flights from Jacksonville to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Jacksonville to St. Louis in December.

Best time to book a flight from Jacksonville to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Jacksonville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to St. Louis

How far ahead should I book a flight from Jacksonville to St. Louis?

What is the cheapest month to book a flight from Jacksonville to St. Louis?

What is the cheapest time of day to fly from JAX to STL?

What is the cheapest day to fly from Jacksonville to St. Louis?

The best insider tips for Jacksonville to St. Louis flights

AI-powered summary based on content written by travel experts. AI can make mistakes.

Cheapflights partnered with top experts to bring you the best recommendations for your Jacksonville to St. Louis trip

Airports

JAX

STL

Our travel experts

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Jacksonville to St. Louis, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Jacksonville to St. Louis?

How popular is this Jacksonville to St. Louis flight route?

How long is the flight from Jacksonville to St. Louis?

What are the cheapest airlines flying from Jacksonville to St. Louis round-trip?

What are the cheapest airlines to fly from Jacksonville to St. Louis one-way?

What are the cheapest flights from Jacksonville to St. Louis?

Can I find deals for flights from Jacksonville to St. Louis that include hotel bookings?

How can I find direct flights from Jacksonville to St. Louis?

Can I find deals for business class flights from Jacksonville to St. Louis?

What is the cheapest month to book a flight from Jacksonville to St. Louis?

Traveling to a place near St. Louis?

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Alternative routes for Jacksonville to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Jacksonville to St. Louis

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Cheapest flights from Jacksonville to St. Louis
Explore the most affordable flight options available from Jacksonville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.