$44+ Cheap flights from Jacksonville (JAX) to Missouri
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — STL
Oct 21 — Oct 281
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Jacksonville to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Jacksonville to Missouri
Cheapest
Best
Last-minute
One-way
Cheapest flights from Jacksonville to MissouriExplore the most affordable flight options available from Jacksonville to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
Explore the most affordable flight options available from Jacksonville to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:20 pm -
1 stop24h 20m
Wed 10/286:44 pm -
1 stop22h 24m
Deal found 9/18![Frontier logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:03 pm -
1 stop23h 37m
Mon 11/236:35 pm -
1 stop21h 32m
Deal found 9/16![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:03 pm -
1 stop24h 36m
Mon 11/306:35 pm -
1 stop19h 36m
Deal found 9/20![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:20 pm -
2 stops29h 53m
Fri 10/236:35 pm -
1 stop23h 11m
Deal found 9/19![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:03 pm -
1 stop24h 36m
Fri 11/276:35 pm -
1 stop21h 32m
Deal found 9/16![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:03 pm -
1 stop23h 37m
Mon 11/306:35 pm -
1 stop19h 36m
Deal found 9/20![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:20 pm -
1 stop24h 20m
Wed 10/286:44 pm -
2 stops24h 44m
Deal found 9/18![Multiple Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:08 pm -
2 stops21h 32m
Mon 11/236:35 pm -
1 stop21h 32m
Deal found 9/16![Multiple Airlines logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:46 pm -
2 stops28h 27m
Fri 10/236:35 pm -
1 stop23h 11m
Deal found 9/18![Frontier logo]()
$209
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:46 pm -
2 stops25h 02m
Tue 10/278:43 pm -
2 stops20h 25m
Deal found 9/17![Frontier logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:46 pm -
2 stops44h 38m
Mon 10/266:35 pm -
1 stop22h 33m
Deal found 9/19![Frontier logo]()
$210
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:10 am -
1 stop6h 05m
Tue 12/17:08 am -
1 stop5h 16m
Deal found 9/18![Delta logo]()
$259
Best flights from Jacksonville to MissouriDiscover carefully curated flight deals from Jacksonville to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
Discover carefully curated flight deals from Jacksonville to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:05 am -
Nonstop2h 15m
Fri 11/275:40 am -
1 stop6h 50m
Deal found 9/16![Southwest logo]()
$276
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:25 am -
1 stop8h 05m
Tue 10/273:10 pm -
1 stop7h 32m
Deal found 9/20![United Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:49 pm -
1 stop7h 07m
Sun 10/256:44 pm -
1 stop4h 12m
Deal found 9/16![Delta logo]()
$380
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:52 pm -
1 stop6h 50m
Mon 10/56:22 pm -
1 stop4h 37m
Deal found 9/19![American Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:45 am -
Nonstop2h 10m
Tue 10/132:25 pm -
1 stop5h 55m
Deal found 9/17![Southwest logo]()
$279
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:50 am -
1 stop7h 46m
Sat 10/317:35 am -
2 stops8h 58m
Deal found 9/20![United Airlines logo]()
$316
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:55 pm -
1 stop5h 35m
Tue 10/2710:20 am -
Nonstop2h 00m
Deal found 9/20![Southwest logo]()
$293
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:58 pm -
1 stop5h 40m
Sat 10/241:48 pm -
2 stops8h 32m
Deal found 9/18![United Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:45 am -
Nonstop2h 10m
Fri 10/237:55 pm -
Nonstop2h 00m
Deal found 9/19![Southwest logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/233:44 pm -
1 stop7h 42m
Fri 11/2710:53 am -
1 stop6h 08m
Deal found 9/17![United Airlines logo]()
$321
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:47 pm -
1 stop5h 05m
Sat 11/283:46 pm -
1 stop7h 09m
Deal found 9/16![American Airlines logo]()
$470
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:08 am -
2 stops8h 26m
Tue 12/17:36 am -
1 stop5h 49m
Deal found 9/18![United Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:45 pm -
1 stop3h 55m
Tue 10/133:20 pm -
1 stop4h 50m
Deal found 9/20![Southwest logo]()
$370
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:40 pm -
2 stops8h 01m
Tue 10/1311:35 am -
2 stops8h 19m
Deal found 9/17![United Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:00 pm -
1 stop3h 55m
Mon 11/237:55 pm -
Nonstop2h 00m
Deal found 9/16![Southwest logo]()
$387
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/89:40 am -
1 stop5h 37m
Tue 10/1311:35 am -
1 stop6h 34m
Deal found 9/20![United Airlines logo]()
$370
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:35 am -
1 stop4h 20m
Sun 11/88:40 pm -
2 stops15h 50m
Deal found 9/20![Southwest logo]()
$402
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:25 am -
2 stops9h 25m
Sat 10/104:53 pm -
1 stop5h 27m
Deal found 9/20![United Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:20 am -
2 stops9h 14m
Wed 11/119:45 am -
2 stops11h 55m
Deal found 9/16![United Airlines logo]()
$396
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:20 am -
2 stops10h 01m
Tue 11/32:55 pm -
1 stop7h 20m
Deal found 9/20![United Airlines logo]()
$416
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:30 am -
2 stops14h 17m
Fri 11/1311:27 am -
2 stops8h 43m
Deal found 9/16![United Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1411:37 am -
2 stops12h 30m
Thu 12/315:45 am -
2 stops9h 37m
Deal found 9/16![United Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:10 am -
2 stops11h 24m
Tue 12/17:36 am -
1 stop5h 49m
Deal found 9/19![United Airlines logo]()
$443
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:04 pm -
1 stop9h 40m
Tue 10/67:32 am -
2 stops12h 22m
Deal found 9/17![United Airlines logo]()
$454
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:05 am -
1 stop6h 04m
Mon 10/57:32 am -
2 stops12h 22m
Deal found 9/16![United Airlines logo]()
$454
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/294:15 pm -
1 stop8h 29m
Sun 11/86:01 am -
1 stop28h 27m
Deal found 9/17![United Airlines logo]()
$522
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:34 pm -
1 stop5h 25m
Wed 10/2811:11 am -
2 stops10h 14m
Deal found 9/20![United Airlines logo]()
$572
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/43:04 pm -
1 stop9h 40m
Tue 10/67:32 am -
1 stop5h 19m
Deal found 9/19![United Airlines logo]()
$752
Last-minute flights from Jacksonville to MissouriDiscover last-minute flight deals from Jacksonville to Missouri. Data last updated September 21, 2026 and is based on user searches.
Discover last-minute flight deals from Jacksonville to Missouri. Data last updated September 21, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:39 pm -
2 stops39h 31m
Mon 10/126:35 pm -
1 stop23h 11m
Deal found 9/17![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:46 pm -
2 stops28h 27m
Wed 10/146:35 pm -
1 stop21h 50m
Deal found 9/16![Frontier logo]()
$234
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:11 pm -
1 stop7h 31m
Sat 10/109:27 am -
1 stop6h 55m
Deal found 9/16![American Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/71:30 pm -
1 stop6h 50m
Sat 10/1010:15 am -
Nonstop2h 00m
Deal found 9/16![Southwest logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:20 pm -
1 stop24h 20m
Thu 10/224:30 pm -
2 stops25h 01m
Deal found 9/17![Frontier logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:46 pm -
2 stops28h 27m
Fri 10/236:35 pm -
1 stop23h 11m
Deal found 9/18![Frontier logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:20 pm -
2 stops29h 53m
Fri 10/236:35 pm -
1 stop23h 11m
Deal found 9/19![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:46 pm -
2 stops44h 38m
Mon 10/266:35 pm -
1 stop22h 33m
Deal found 9/19![Frontier logo]()
$210
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:46 pm -
2 stops25h 02m
Tue 10/278:43 pm -
2 stops20h 25m
Deal found 9/17![Frontier logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:20 pm -
1 stop24h 20m
Wed 10/286:44 pm -
1 stop22h 24m
Deal found 9/18![Frontier logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:20 pm -
1 stop24h 20m
Wed 10/286:44 pm -
2 stops24h 44m
Deal found 9/18![Multiple Airlines logo]()
$171
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:40 am -
1 stop6h 09m
Mon 11/29:12 am -
1 stop6h 49m
Deal found 9/20![American Airlines logo]()
$259
One-way flights from Jacksonville to MissouriSearch for one-way flight options from Jacksonville to Missouri. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
Search for one-way flight options from Jacksonville to Missouri. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:03 pm -
1 stop23h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$44
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:03 pm -
1 stop24h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Frontier logo]()
$49
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:20 pm -
1 stop24h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$58
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:03 pm -
1 stop23h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Frontier logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:20 pm -
1 stop24h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:20 pm -
1 stop24h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Frontier logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/153:56 pm -
1 stop20h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$98
This Mytrip deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:46 pm -
2 stops25h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Frontier logo]()
$111
This Mytrip deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:03 pm -
2 stops25h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Frontier logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:00 pm -
1 stop20h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$127
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:10 am -
1 stop4h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Southwest logo]()
$130
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:40 pm -
2 stops10h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![United Airlines logo]()
$135
Find flight deals from Jacksonville to Missouri
Keep the following information in mind while searching for Jacksonville to Missouri flight deals. Data was last updated September 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $87 (Kiwi.com) |
One-way from | $44 (Kiwi.com) |
Popular in | March |
Cheapest in | October |
Average price | $376 |
Good round-trip deal | $381 or less |
Good one-way deal | $149 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Jacksonville to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
Use the filters below to find and compare flights from Jacksonville to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Sat 10/10
9:40 am-3:43 pm
1 stop7h 03m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$120
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Tue 12/15
6:35 am-1:50 pm
2 stops8h 15m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$126
JacksonvilleKansas City
JAX Jacksonville - MCI Kansas City
JAXMCI
Jacksonville
Thu 10/29
3:00 pm-10:06 am
1 stop20h 06m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$127
JacksonvilleKansas City
JAX Jacksonville - MCI Kansas City
JAXMCI
Jacksonville
Tue 12/29
5:00 am-9:24 am
1 stop5h 24m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$130
JacksonvilleKansas City
JAX Jacksonville - MCI Kansas City
JAXMCI
Jacksonville
Tue 10/20
6:10 am-9:28 am
1 stop4h 18m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$130
JacksonvilleKansas City
JAX Jacksonville - MCI Kansas City
JAXMCI
Jacksonville
Mon 10/19
7:35 pm-12:30 am
1 stop5h 55m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$130
JacksonvilleKansas City
JAX Jacksonville - MCI Kansas City
JAXMCI
Jacksonville
Sat 10/17
12:40 pm-10:00 pm
2 stops10h 20m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$135
JacksonvilleKansas City
JAX Jacksonville - MCI Kansas City
JAXMCI
Jacksonville
Wed 10/14
6:10 am-9:35 am
1 stop4h 25m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$141
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Wed 12/16
6:05 am-7:20 am
Nonstop2h 15m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$142
Quickest round-trip
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Mon 10/19
5:45 am-6:55 am
Nonstop2h 10m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$142
Showing 1-10 of 52 resultsSorted by cheapest first
Best time to book a flight from Jacksonville to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Jacksonville with our price prediction graph.
JAX-STL
JAX-SGF
JAX-MCI
JAX-JLN
JAX-CGI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Jacksonville to Missouri
JAX-USMO
JAX-STL
JAX-SGF
JAX-MCI
JAX-JLN
What is the cheapest month to book a flight from Jacksonville to Missouri?
Currently, October is the cheapest month in which you can book a flight from Jacksonville to Missouri (average of $341). Flying from Jacksonville to Missouri in May is currently the most expensive (average of $469). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from JAX to MO?
Find hourly flight availability from Jacksonville to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 21, 2026.
It’s optimal to fly from Jacksonville to Missouri at noon. By choosing this option you can save up to 12% on the cost of your flight, compared to a flight in the morning.
How much does it cost to fly round-trip from Jacksonville to Missouri?
Airfare is below average for this route at the moment.
Jacksonville to Missouri flights typically cost between $312 and $435 in October.The cheapest round-trip price found within the last 5 days was $87 on Frontier (Oct 13-Oct 21).
How far ahead should I book a flight from Jacksonville to Missouri?
The best time to book flights from Jacksonville to Missouri is 79 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated September 21, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Jacksonville to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Jacksonville to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Jacksonville to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Jacksonville to Missouri by cabin class
Find flights from Jacksonville to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Jacksonville and Missouri flights
Browse other Jacksonville and Missouri flight options. Last updated on September 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Jacksonville to Missouri flights
Consider these flights traveling from Jacksonville to Missouri.
Top 4 airlines flying from Jacksonville to Missouri
Discover the top 4 airlines that operate flights from Jacksonville to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$425 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$253 | Average$373 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$254 | Average$390 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$278 | Average$393 | FlexibilityNo cancel fee | On-time63% |