$102+ Cheap flights from Jacksonville (JAX) to Missouri
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — STL
Dec 4 — Dec 111
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Jacksonville to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Jacksonville to Missouri
Cheapest
Best
Last-minute
One-way
Cheapest flights from Jacksonville to MissouriExplore the most affordable flight options available from Jacksonville to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
Explore the most affordable flight options available from Jacksonville to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/75:47 pm -
2 stops31h 25m
Fri 12/1112:02 pm -
1 stop4h 00m
Deal found 11/3![Frontier logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/69:08 pm -
2 stops15h 09m
Fri 12/1112:02 pm -
1 stop25h 18m
Deal found 11/3![Multiple Airlines logo]()
$213
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:45 pm -
1 stop6h 02m
Tue 12/85:45 am -
1 stop8h 32m
Deal found 10/30![United Airlines logo]()
$254
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:49 am -
1 stop7h 48m
Sat 12/512:00 pm -
1 stop5h 47m
Deal found 11/1![American Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:35 am -
1 stop4h 20m
Tue 12/87:00 am -
2 stops10h 20m
Deal found 11/1![Southwest logo]()
$264
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:55 pm -
2 stops18h 02m
Sun 12/66:20 pm -
2 stops21h 42m
Deal found 11/1![Frontier logo]()
$269
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:05 am -
Nonstop2h 15m
Mon 12/76:15 pm -
Nonstop2h 00m
Deal found 11/3![Southwest logo]()
$283
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:45 am -
Nonstop2h 20m
Fri 11/2710:15 am -
1 stop5h 25m
Deal found 11/1![Southwest logo]()
$288
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:07 pm -
1 stop7h 28m
Fri 11/275:00 am -
1 stop6h 43m
Deal found 11/1![American Airlines logo]()
$293
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:35 am -
2 stops8h 15m
Fri 12/185:30 am -
1 stop4h 55m
Deal found 11/3![Southwest logo]()
$298
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:05 am -
Nonstop2h 15m
Wed 12/238:00 pm -
Nonstop2h 05m
Deal found 11/1![Southwest logo]()
$299
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:05 am -
1 stop5h 57m
Tue 1/55:00 am -
1 stop5h 38m
Deal found 10/31![American Airlines logo]()
$311
Best flights from Jacksonville to MissouriDiscover carefully curated flight deals from Jacksonville to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
Discover carefully curated flight deals from Jacksonville to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/16:40 pm -
1 stop4h 30m
Fri 2/265:15 am -
1 stop6h 00m
Deal found 10/31![Southwest logo]()
$259
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:00 am -
1 stop6h 29m
Wed 12/237:05 am -
1 stop6h 22m
Deal found 11/1![Delta logo]()
$293
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:30 am -
1 stop8h 08m
Mon 12/1411:25 am -
1 stop5h 33m
Deal found 11/4![United Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:55 pm -
1 stop5h 22m
Sat 12/127:17 am -
1 stop5h 53m
Deal found 10/30![American Airlines logo]()
$328
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:35 am -
1 stop4h 20m
Tue 12/87:00 am -
2 stops10h 20m
Deal found 11/1![Southwest logo]()
$264
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/135:45 pm -
1 stop5h 51m
Sat 12/195:09 pm -
1 stop3h 45m
Deal found 11/1![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1611:10 am -
2 stops7h 15m
Wed 12/234:50 pm -
1 stop4h 25m
Deal found 11/1![Southwest logo]()
$298
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:40 am -
1 stop5h 48m
Sat 12/1211:25 am -
2 stops10h 15m
Deal found 10/30![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:05 am -
Nonstop2h 15m
Sun 12/67:55 pm -
Nonstop2h 00m
Deal found 11/3![Southwest logo]()
$312
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/174:45 pm -
1 stop7h 13m
Sat 11/213:00 pm -
1 stop7h 42m
Deal found 11/2![United Airlines logo]()
$358
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:00 am -
Nonstop2h 20m
Tue 12/16:15 pm -
Nonstop2h 00m
Deal found 11/2![Southwest logo]()
$312
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:00 am -
1 stop9h 13m
Tue 12/86:00 am -
2 stops8h 03m
Deal found 10/30![United Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:54 pm -
1 stop4h 16m
Tue 12/15:41 pm -
1 stop5h 15m
Deal found 11/2![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:30 am -
1 stop8h 15m
Sat 12/56:00 am -
2 stops10h 53m
Deal found 11/3![United Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:59 pm -
1 stop4h 27m
Tue 12/15:41 pm -
1 stop5h 15m
Deal found 11/1![Delta logo]()
$409
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/73:45 pm -
2 stops7h 45m
Tue 12/812:20 pm -
2 stops8h 00m
Deal found 10/30![Southwest logo]()
$340
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:05 am -
1 stop5h 22m
Sun 11/297:10 am -
1 stop6h 45m
Deal found 10/31![Delta logo]()
$409
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:35 am -
2 stops8h 15m
Fri 12/1811:10 am -
2 stops8h 25m
Deal found 11/3![Southwest logo]()
$360
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:29 pm -
1 stop5h 19m
Tue 11/177:35 am -
2 stops12h 35m
Deal found 11/3![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/215:05 pm -
1 stop6h 21m
Fri 4/303:55 pm -
1 stop5h 48m
Deal found 11/1![Delta logo]()
$437
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:10 am -
2 stops9h 23m
Wed 11/1811:11 am -
2 stops8h 59m
Deal found 10/31![United Airlines logo]()
$404
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:20 am -
Nonstop2h 15m
Mon 11/308:00 pm -
Nonstop2h 05m
Deal found 10/31![Southwest logo]()
$375
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:35 am -
1 stop5h 34m
Mon 11/1611:11 am -
2 stops10h 29m
Deal found 11/1![United Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/307:03 am -
1 stop8h 07m
Tue 1/57:30 am -
2 stops11h 49m
Deal found 11/1![United Airlines logo]()
$409
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/296:25 am -
1 stop4h 10m
Thu 5/69:20 am -
1 stop6h 05m
Deal found 10/30![Southwest logo]()
$437
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/97:00 am -
2 stops10h 24m
Tue 1/127:30 am -
2 stops11h 49m
Deal found 10/31![United Airlines logo]()
$421
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:44 pm -
1 stop7h 15m
Mon 12/74:50 pm -
1 stop5h 23m
Deal found 11/3![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/64:10 pm -
1 stop8h 34m
Sat 1/95:00 am -
2 stops8h 56m
Deal found 10/30![United Airlines logo]()
$464
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/134:10 pm -
1 stop6h 13m
Wed 12/163:04 pm -
1 stop5h 32m
Deal found 11/3![United Airlines logo]()
$556
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/167:30 am -
1 stop27h 18m
Wed 1/205:00 am -
1 stop7h 57m
Deal found 11/2![United Airlines logo]()
$590
Last-minute flights from Jacksonville to MissouriDiscover last-minute flight deals from Jacksonville to Missouri. Data last updated November 4, 2026 and is based on user searches.
Discover last-minute flight deals from Jacksonville to Missouri. Data last updated November 4, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:45 am -
Nonstop2h 20m
Fri 11/2710:15 am -
1 stop5h 25m
Deal found 11/1![Southwest logo]()
$288
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:07 pm -
1 stop7h 28m
Fri 11/275:00 am -
1 stop6h 43m
Deal found 11/1![American Airlines logo]()
$293
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:49 am -
1 stop7h 48m
Sat 12/512:00 pm -
1 stop5h 47m
Deal found 11/1![American Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:35 am -
1 stop4h 20m
Tue 12/87:00 am -
2 stops10h 20m
Deal found 11/1![Southwest logo]()
$264
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:05 am -
Nonstop2h 15m
Mon 12/76:15 pm -
Nonstop2h 00m
Deal found 11/3![Southwest logo]()
$283
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:55 pm -
2 stops18h 02m
Sun 12/66:20 pm -
2 stops21h 42m
Deal found 11/1![Frontier logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/69:08 pm -
2 stops15h 09m
Fri 12/1112:02 pm -
1 stop25h 18m
Deal found 11/3![Multiple Airlines logo]()
$213
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/75:47 pm -
2 stops31h 25m
Fri 12/1112:02 pm -
1 stop4h 00m
Deal found 11/3![Frontier logo]()
$167
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:45 pm -
1 stop6h 02m
Tue 12/85:45 am -
1 stop8h 32m
Deal found 10/30![United Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:35 am -
2 stops8h 15m
Fri 12/185:30 am -
1 stop4h 55m
Deal found 11/3![Southwest logo]()
$298
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:05 am -
Nonstop2h 15m
Wed 12/238:00 pm -
Nonstop2h 05m
Deal found 11/1![Southwest logo]()
$299
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:05 am -
1 stop5h 57m
Tue 1/55:00 am -
1 stop5h 38m
Deal found 10/31![American Airlines logo]()
$311
One-way flights from Jacksonville to MissouriSearch for one-way flight options from Jacksonville to Missouri. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
Search for one-way flight options from Jacksonville to Missouri. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/75:47 pm -
2 stops31h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:08 pm -
2 stops15h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$117
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:17 am -
1 stop6h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![American Airlines logo]()
$130
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:39 pm -
2 stops24h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/303:56 pm -
2 stops44h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Multiple Airlines logo]()
$141
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:45 am -
Nonstop2h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Southwest logo]()
$142
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:07 pm -
1 stop7h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![American Airlines logo]()
$147
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:45 am -
Nonstop2h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Southwest logo]()
$171
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/161:50 pm -
2 stops8h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Southwest logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/710:39 pm -
3 stops37h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$175
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:24 pm -
1 stop4h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![American Airlines logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:03 pm -
2 stops25h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Frontier logo]()
$180
Find flight deals from Jacksonville to Missouri
Keep the following information in mind while searching for Jacksonville to Missouri flight deals. Data was last updated November 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $167 (Mytrip) |
One-way from | $102 (Kiwi.com) |
Popular in | March |
Cheapest in | February |
Average price | $427 |
Good round-trip deal | $330 or less |
Good one-way deal | $220 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Jacksonville to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
Use the filters below to find and compare flights from Jacksonville to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Mon 12/7
5:47 pm-12:12 am
2 stops31h 25m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$102
JacksonvilleKansas City
JAX Jacksonville - MCI Kansas City
JAXMCI
Jacksonville
Wed 12/2
6:50 pm-11:56 pm
1 stop6h 06m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$130
JacksonvilleKansas City
JAX Jacksonville - MCI Kansas City
JAXMCI
Jacksonville
Fri 2/12
9:05 pm-12:30 am
1 stop4h 25m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$130
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Mon 11/30
3:56 pm-11:10 am
2 stops44h 14m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$141
Quickest round-trip
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Thu 12/3
6:05 am-7:20 am
Nonstop2h 15m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$142
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Mon 11/23
5:45 am-7:05 am
Nonstop2h 20m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$142
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Mon 11/23
5:07 pm-11:35 pm
1 stop7h 28m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$147
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Tue 2/16
6:40 pm-9:45 pm
1 stop4h 05m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$147
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Sun 11/22
5:45 am-7:05 am
Nonstop2h 20m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$171
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Tue 2/16
2:50 pm-12:04 am
3 stops34h 14m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$184
Showing 1-10 of 51 resultsSorted by cheapest first
Best time to book a flight from Jacksonville to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Jacksonville with our price prediction graph.
JAX-STL
JAX-MCI
JAX-SGF
JAX-COU
JAX-JLN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Jacksonville to Missouri
JAX-USMO
JAX-STL
JAX-MCI
JAX-SGF
JAX-COU
What is the cheapest month to book a flight from Jacksonville to Missouri?
Currently, January is the cheapest month in which you can book a flight from Jacksonville to Missouri (average of $353). Flying from Jacksonville to Missouri in May is currently the most expensive (average of $466). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from JAX to MO?
Find hourly flight availability from Jacksonville to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 4, 2026.
It’s optimal to fly from Jacksonville to Missouri at noon. By choosing this option you can save up to 16% on the cost of your flight, compared to a flight in the evening.
How much does it cost to fly round-trip from Jacksonville to Missouri?
Airfare is below average for this route at the moment.
Jacksonville to Missouri flights typically cost between $340 and $450 in December.The cheapest round-trip price found within the last 5 days was $167 on Frontier (Dec 7-Dec 11).
How far ahead should I book a flight from Jacksonville to Missouri?
The best time to book flights from Jacksonville to Missouri is 80 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 4, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Jacksonville to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Related info for your journey
Find useful and relevant information for your journey from Jacksonville to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Jacksonville to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Jacksonville to Missouri by cabin class
Find flights from Jacksonville to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Jacksonville and Missouri flights
Browse other Jacksonville and Missouri flight options. Last updated on November 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Jacksonville to Missouri flights
Consider these flights traveling from Jacksonville to Missouri.
Top 4 airlines flying from Jacksonville to Missouri
Discover the top 4 airlines that operate flights from Jacksonville to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$240 | Average$433 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$254 | Average$399 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$272 | Average$392 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$308 | Average$358 | FlexibilityNo cancel fee | On-time69% |