$46+ Cheap flights from Missouri to Jacksonville (JAX)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel.
STL — JAX
Sep 27 — Oct 41
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Jacksonville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Jacksonville
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Cheapest flights from Missouri to JacksonvilleExplore the most affordable flight options available from Missouri to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 28, 2026.
Explore the most affordable flight options available from Missouri to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:35 pm -
1 stop21h 50m
Tue 10/277:03 pm -
1 stop23h 37m
Deal found 8/27![Frontier logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:29 pm -
1 stop25h 56m
Tue 10/137:46 pm -
1 stop22h 54m
Deal found 8/24![Frontier logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:29 pm -
1 stop27h 32m
Tue 10/137:46 pm -
1 stop22h 54m
Deal found 8/24![Frontier logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:29 pm -
1 stop27h 32m
Tue 9/227:46 pm -
1 stop18h 24m
Deal found 8/27![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:29 pm -
1 stop27h 32m
Tue 9/227:46 pm -
1 stop18h 24m
Deal found 8/27![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:29 pm -
1 stop27h 32m
Sun 9/207:46 pm -
1 stop18h 24m
Deal found 8/24![Frontier logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:29 pm -
1 stop27h 32m
Thu 9/177:46 pm -
1 stop18h 24m
Deal found 8/24![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:29 pm -
1 stop27h 32m
Thu 9/247:46 pm -
1 stop18h 24m
Deal found 8/27![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:29 pm -
1 stop27h 32m
Sun 10/116:20 pm -
1 stop24h 20m
Deal found 8/24![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:29 pm -
1 stop25h 56m
Sun 10/116:20 pm -
1 stop24h 20m
Deal found 8/23![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:29 pm -
1 stop27h 32m
Wed 9/307:46 pm -
2 stops14h 49m
Deal found 8/26![Frontier logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:29 pm -
1 stop25h 56m
Wed 10/147:46 pm -
2 stops28h 27m
Deal found 8/24![Frontier logo]()
$139
Best flights from Missouri to JacksonvilleDiscover carefully curated flight deals from Missouri to Jacksonville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 28, 2026.
Discover carefully curated flight deals from Missouri to Jacksonville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 28, 2026.
This Southwest deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:55 pm -
Nonstop1h 55m
Mon 10/268:45 pm -
1 stop3h 50m
Deal found 8/24![Southwest logo]()
$272
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:35 am -
1 stop6h 34m
Wed 9/303:45 pm -
1 stop6h 24m
Deal found 8/26![United Airlines logo]()
$298
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:29 pm -
1 stop5h 43m
Tue 12/15:45 pm -
1 stop4h 53m
Deal found 8/23![Delta logo]()
$312
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:12 am -
1 stop4h 36m
Mon 11/165:08 pm -
1 stop6h 34m
Deal found 8/27![American Airlines logo]()
$353
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:10 am -
1 stop4h 50m
Wed 10/214:05 pm -
1 stop7h 20m
Deal found 8/26![Southwest logo]()
$282
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:55 pm -
Nonstop1h 55m
Wed 10/76:10 am -
Nonstop2h 15m
Deal found 8/25![Southwest logo]()
$288
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am -
1 stop4h 53m
Mon 10/267:00 pm -
1 stop4h 19m
Deal found 8/23![Delta logo]()
$321
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:01 am -
2 stops10h 32m
Fri 11/134:15 pm -
1 stop8h 29m
Deal found 8/25![United Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:55 pm -
Nonstop1h 55m
Fri 10/235:45 am -
Nonstop2h 10m
Deal found 8/25![Southwest logo]()
$288
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:27 am -
2 stops10h 08m
Thu 10/293:46 pm -
1 stop7h 05m
Deal found 8/26![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/239:35 am -
2 stops9h 15m
Wed 9/306:45 am -
2 stops7h 45m
Deal found 8/25![Southwest logo]()
$309
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1911:22 am -
2 stops8h 32m
Sat 9/2612:40 pm -
2 stops8h 07m
Deal found 8/24![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:43 am -
1 stop5h 01m
Thu 9/106:59 pm -
1 stop5h 52m
Deal found 8/24![Delta logo]()
$389
This Southwest deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:15 am -
Nonstop2h 00m
Sun 10/185:55 am -
Nonstop2h 10m
Deal found 8/23![Southwest logo]()
$317
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2210:00 am -
2 stops9h 54m
Tue 9/2912:40 pm -
2 stops10h 20m
Deal found 8/24![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1812:10 pm -
1 stop5h 44m
Thu 12/247:00 am -
1 stop6h 32m
Deal found 8/26![Delta logo]()
$418
This Southwest deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:45 am -
1 stop5h 35m
Wed 9/306:15 am -
Nonstop2h 10m
Deal found 8/24![Southwest logo]()
$317
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:05 pm -
1 stop7h 15m
Sat 10/39:40 am -
1 stop5h 50m
Deal found 8/24![United Airlines logo]()
$371
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/183:20 pm -
2 stops6h 05m
Wed 10/214:05 pm -
1 stop7h 20m
Deal found 8/27![Southwest logo]()
$343
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:02 am -
1 stop6h 34m
Wed 12/94:20 pm -
1 stop8h 24m
Deal found 8/27![United Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:19 pm -
1 stop4h 44m
Mon 9/216:59 pm -
1 stop4h 09m
Deal found 8/24![Delta logo]()
$488
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:19 am -
1 stop6h 50m
Wed 10/1412:40 pm -
2 stops11h 15m
Deal found 8/24![United Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:05 am -
1 stop8h 10m
Fri 9/113:50 pm -
2 stops7h 50m
Deal found 8/23![Southwest logo]()
$394
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:00 am -
1 stop6h 28m
Sun 11/87:11 am -
1 stop8h 22m
Deal found 8/24![United Airlines logo]()
$414
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:50 am -
1 stop4h 30m
Fri 9/182:00 pm -
2 stops9h 20m
Deal found 8/25![Southwest logo]()
$406
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/911:15 am -
1 stop6h 54m
Fri 10/164:58 pm -
1 stop6h 57m
Deal found 8/24![United Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:30 am -
1 stop5h 35m
Sat 9/129:25 am -
2 stops10h 21m
Deal found 8/23![United Airlines logo]()
$434
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:15 am -
2 stops8h 39m
Mon 10/194:58 pm -
1 stop6h 57m
Deal found 8/24![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:00 am -
2 stops13h 40m
Mon 11/164:45 pm -
1 stop7h 13m
Deal found 8/27![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:01 am -
1 stop7h 20m
Sat 11/149:45 am -
1 stop25h 14m
Deal found 8/25![United Airlines logo]()
$470
Last-minute flights from Missouri to JacksonvilleDiscover last-minute flight deals from Missouri to Jacksonville. Data last updated August 28, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Jacksonville. Data last updated August 28, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am -
1 stop6h 36m
Sat 9/123:54 pm -
1 stop5h 08m
Deal found 8/27![Delta logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:29 pm -
1 stop27h 32m
Sun 9/207:46 pm -
1 stop18h 24m
Deal found 8/24![Frontier logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:29 pm -
1 stop27h 32m
Thu 9/177:46 pm -
1 stop18h 24m
Deal found 8/24![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:29 pm -
2 stops18h 11m
Tue 9/157:46 pm -
1 stop18h 24m
Deal found 8/24![Multiple Airlines logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:29 pm -
1 stop27h 32m
Tue 9/227:46 pm -
1 stop18h 24m
Deal found 8/27![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:29 pm -
1 stop27h 32m
Thu 9/247:46 pm -
1 stop18h 24m
Deal found 8/27![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:29 pm -
1 stop27h 32m
Wed 9/237:46 pm -
2 stops14h 49m
Deal found 8/27![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:29 pm -
1 stop27h 32m
Tue 9/227:46 pm -
1 stop18h 24m
Deal found 8/27![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:29 pm -
1 stop27h 32m
Wed 9/237:46 pm -
2 stops14h 49m
Deal found 8/27![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:29 pm -
1 stop27h 32m
Wed 9/307:46 pm -
2 stops14h 49m
Deal found 8/26![Frontier logo]()
$137
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:15 am -
1 stop6h 30m
Wed 9/306:45 am -
2 stops7h 45m
Deal found 8/25![Southwest logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:29 pm -
1 stop27h 32m
Wed 9/307:46 pm -
2 stops14h 49m
Deal found 8/26![Frontier logo]()
$142
One-way flights from Missouri to JacksonvilleSearch for one-way flight options from Missouri to Jacksonville. Find affordable one-way fares based on user searches. Data last updated August 28, 2026.
Search for one-way flight options from Missouri to Jacksonville. Find affordable one-way fares based on user searches. Data last updated August 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:29 pm -
1 stop27h 32m
Deal found 8/24![Frontier logo]()
$46
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:35 pm -
1 stop23h 11m
Deal found 8/26![Frontier logo]()
$48
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:29 pm -
1 stop27h 32m
Deal found 8/27![Frontier logo]()
$49
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:35 pm -
1 stop22h 33m
Deal found 8/26![Frontier logo]()
$50
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:29 pm -
1 stop27h 32m
Deal found 8/27![Frontier logo]()
$54
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:29 pm -
1 stop27h 32m
Deal found 8/25![Frontier logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:35 pm -
1 stop23h 11m
Deal found 8/26![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:17 pm -
2 stops29h 44m
Deal found 8/25![Frontier logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2110:30 pm -
2 stops19h 31m
Deal found 8/23![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:32 pm -
2 stops45h 29m
Deal found 8/23![Frontier logo]()
$128
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am -
1 stop6h 36m
Deal found 8/27![Delta logo]()
$130
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:22 am -
2 stops8h 32m
Deal found 8/27![United Airlines logo]()
$135
Find flight deals from Missouri to Jacksonville
Keep the following information in mind while searching for Missouri to Jacksonville flight deals. Data was last updated August 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $88 (Kiwi.com) |
One-way from | $46 (Kiwi.com) |
Popular in | November |
Cheapest in | September |
Average price | $368 |
Good round-trip deal | $470 or less |
Good one-way deal | $314 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Jacksonville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 28, 2026.
Use the filters below to find and compare flights from Missouri to Jacksonville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisJacksonville
STL Lambert-St Louis - JAX Jacksonville
STLJAX
Lambert-St Louis
Thu 10/22
7:55 pm-10:50 pm
Nonstop1h 55m
Jacksonville
Mon 10/26
8:45 pm-11:35 pm
1 stop3h 50m
$272
St. LouisJacksonville
STL Lambert-St Louis - JAX Jacksonville
STLJAX
Lambert-St Louis
Thu 10/15
5:10 am-11:00 am
1 stop4h 50m
Jacksonville
Wed 10/21
4:05 pm-10:25 pm
1 stop7h 20m
$282
St. LouisJacksonville
STL Lambert-St Louis - JAX Jacksonville
STLJAX
Lambert-St Louis
Fri 10/2
7:55 pm-10:50 pm
Nonstop1h 55m
Jacksonville
Wed 10/7
6:10 am-7:25 am
Nonstop2h 15m
$288
Quickest round-trip
St. LouisJacksonville
STL Lambert-St Louis - JAX Jacksonville
STLJAX
Lambert-St Louis
Mon 10/19
7:55 pm-10:50 pm
Nonstop1h 55m
Jacksonville
Fri 10/23
5:45 am-6:55 am
Nonstop2h 10m
$288
St. LouisJacksonville
STL Lambert-St Louis - JAX Jacksonville
STLJAX
Lambert-St Louis
Fri 9/25
11:35 am-7:09 pm
1 stop6h 34m
Jacksonville
Wed 9/30
3:45 pm-9:09 pm
1 stop6h 24m
$298
Kansas CityJacksonville
MCI Kansas City - JAX Jacksonville
MCIJAX
Kansas City
Wed 9/23
9:35 am-7:50 pm
2 stops9h 15m
Jacksonville
Wed 9/30
6:45 am-1:30 pm
2 stops7h 45m
$309
St. LouisJacksonville
STL Lambert-St Louis - JAX Jacksonville
STLJAX
Lambert-St Louis
Tue 11/24
12:29 pm-7:12 pm
1 stop5h 43m
Jacksonville
Tue 12/1
5:45 pm-9:38 pm
1 stop4h 53m
$312
St. LouisJacksonville
STL Lambert-St Louis - JAX Jacksonville
STLJAX
Lambert-St Louis
Sat 10/10
10:15 am-1:15 pm
Nonstop2h 00m
Jacksonville
Sun 10/18
5:55 am-7:05 am
Nonstop2h 10m
$317
St. LouisJacksonville
STL Lambert-St Louis - JAX Jacksonville
STLJAX
Lambert-St Louis
Thu 9/24
5:45 am-12:20 pm
1 stop5h 35m
Jacksonville
Wed 9/30
6:15 am-7:25 am
Nonstop2h 10m
$317
SpringfieldJacksonville
SGF Springfield-Branson - JAX Jacksonville
SGFJAX
Springfield-Branson
Sat 10/17
6:00 am-11:53 am
1 stop4h 53m
Jacksonville
Mon 10/26
7:00 pm-10:19 pm
1 stop4h 19m
$321
Showing 1-10 of 53 resultsSorted by cheapest first
Best time to book a flight from Missouri to Jacksonville
Have a flexible travel schedule? Discover the best time to fly to Jacksonville from Missouri with our price prediction graph.
STL-JAX
MCI-JAX
COU-JAX
SGF-JAX
JLN-JAX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Jacksonville
USMO-JAX
STL-JAX
MCI-JAX
COU-JAX
SGF-JAX
What is the cheapest month to book a flight from Missouri to Jacksonville?
Currently, October is the cheapest month in which you can book a flight from Missouri to Jacksonville (average of $327). Flying from Missouri to Jacksonville in July is currently the most expensive (average of $412). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to JAX?
Find hourly flight availability from Missouri to Jacksonville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 28, 2026.
It’s optimal to fly from Missouri to Jacksonville in the evening. By choosing this option you can save up to 17% on the cost of your flight, compared to a flight at noon.
How much does it cost to fly round-trip from Missouri to Jacksonville?
Airfare is below average for this route at the moment.
Missouri to Jacksonville flights typically cost between $258 and $445 in October.The cheapest round-trip price found within the last 5 days was $88 on Frontier (Oct 21-Oct 27).
How far ahead should I book a flight from Missouri to Jacksonville?
The price you pay for your flight from Missouri to Jacksonville may vary depending on when you book. For the best chance of a lower fare, look to book 38 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Jacksonville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Jacksonville?
Book flights to Jacksonville if you plan to visit one of these locationsJacksonville Beach
Fernandina Beach
Orange Park
Kingsland
Waycross
Atlantic Beach
Yulee
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Alternative routes for Missouri to Jacksonville
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Search flights from Missouri to Jacksonville by cabin class
Find flights from Missouri to Jacksonville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Jacksonville
Explore flights to Jacksonville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 28, 2026.
Missouri and Jacksonville flights
Browse other Missouri and Jacksonville flight options. Last updated on August 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Jacksonville flights
Consider these flights traveling from Missouri to Jacksonville.
Top 6 airlines flying from Missouri to Jacksonville
Discover the top 6 airlines that operate flights from Missouri to Jacksonville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$80 | Average$111 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$168 | Average$385 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$244 | Average$371 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$251 | Average$377 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$251 | Average$390 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$260 | Average$371 | FlexibilityNo cancel fee | On-time71% |