$63+ Cheap flights from Missouri to Jacksonville (JAX)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/23. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — JAX
Jun 21 — Jun 281
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to JacksonvilleExplore the most affordable flight options available from Missouri to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.
Explore the most affordable flight options available from Missouri to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:31 pm
STL
- JAX
1 stop22h 02m
Frontier
Sun 7/56:28 pm
JAX
- STL
1 stop15h 29m
Frontier
Deal found 5/18![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:06 pm
STL
- JAX
1 stop23h 27m
Frontier
Mon 6/226:28 pm
JAX
- STL
1 stop24h 02m
Frontier
Deal found 5/18![Frontier logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:16 pm
MCI
- JAX
1 stop22h 17m
Frontier
Fri 6/196:28 pm
JAX
- MCI
1 stop23h 53m
Frontier
Deal found 5/18![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:06 pm
STL
- JAX
1 stop23h 27m
Frontier
Sun 6/286:28 pm
JAX
- STL
1 stop15h 24m
Frontier
Deal found 5/19![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/64:52 pm
STL
- JAX
1 stop23h 41m
Frontier
Thu 7/96:29 pm
JAX
- STL
1 stop15h 28m
Frontier
Deal found 5/20![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:07 pm
MCI
- JAX
1 stop22h 27m
Frontier
Thu 8/136:29 pm
JAX
- MCI
1 stop23h 41m
Frontier
Deal found 5/21![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:34 pm
STL
- JAX
1 stop22h 00m
Frontier
Fri 8/146:29 pm
JAX
- STL
1 stop15h 28m
Frontier
Deal found 5/21![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:34 pm
STL
- JAX
1 stop22h 00m
Frontier
Sun 8/96:29 pm
JAX
- STL
1 stop15h 28m
Frontier
Deal found 5/21![Frontier logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:31 pm
STL
- JAX
1 stop22h 02m
Frontier
Mon 6/296:28 pm
JAX
- STL
1 stop24h 02m
Frontier
Deal found 5/21![Frontier logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:34 pm
STL
- JAX
1 stop22h 00m
Frontier
Sun 8/96:29 pm
JAX
- STL
1 stop15h 28m
Frontier
Deal found 5/21![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:34 pm
STL
- JAX
1 stop22h 00m
Frontier
Tue 8/116:29 pm
JAX
- STL
1 stop15h 28m
Frontier
Deal found 5/21![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:52 pm
STL
- JAX
1 stop23h 45m
Frontier
Mon 8/246:28 pm
JAX
- STL
1 stop24h 02m
Frontier
Deal found 5/17![Frontier logo]()
$148
Best flights from Missouri to JacksonvilleDiscover carefully curated flight deals from Missouri to Jacksonville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 22, 2026.
Discover carefully curated flight deals from Missouri to Jacksonville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 22, 2026.
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:19 pm
COU
- JAX
1 stop5h 23m
American Airlines
Sat 7/116:11 pm
JAX
- COU
1 stop4h 41m
American Airlines
Deal found 5/17![American Airlines logo]()
$298
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/223:35 pm
STL
- JAX
1 stop6h 00m
Southwest
Tue 6/308:25 am
JAX
- STL
Nonstop2h 10m
Southwest
Deal found 5/21![Southwest logo]()
$300
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:08 am
STL
- JAX
1 stop5h 37m
Delta
Mon 7/137:09 pm
JAX
- STL
1 stop5h 44m
Delta
Deal found 5/19![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:57 pm
JLN
- JAX
1 stop6h 43m
United Airlines
Tue 6/97:20 am
JAX
- JLN
1 stop7h 02m
United Airlines
Deal found 5/21![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/172:05 pm
STL
- JAX
Nonstop2h 00m
Southwest
Mon 8/247:50 am
JAX
- STL
1 stop4h 45m
Southwest
Deal found 5/17![Southwest logo]()
$303
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/41:57 pm
JLN
- JAX
1 stop6h 43m
United Airlines
Mon 6/87:20 am
JAX
- JLN
1 stop7h 02m
United Airlines
Deal found 5/20![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:20 pm
STL
- JAX
1 stop6h 40m
Southwest
Fri 8/217:50 am
JAX
- STL
1 stop4h 45m
Southwest
Deal found 5/18![Southwest logo]()
$311
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:30 am
SGF
- JAX
2 stops12h 24m
United Airlines
Wed 8/2611:51 am
JAX
- SGF
2 stops11h 01m
United Airlines
Deal found 5/19![United Airlines logo]()
$340
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/192:30 pm
STL
- JAX
1 stop6h 05m
Southwest
Mon 6/227:15 pm
JAX
- STL
1 stop4h 35m
Southwest
Deal found 5/19![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:53 am
MCI
- JAX
1 stop5h 34m
United Airlines
Wed 7/154:48 pm
JAX
- MCI
1 stop8h 11m
United Airlines
Deal found 5/17![United Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:45 pm
STL
- JAX
1 stop4h 20m
Southwest
Tue 8/186:15 am
JAX
- STL
Nonstop2h 10m
Southwest
Deal found 5/17![Southwest logo]()
$332
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:45 pm
SGF
- JAX
1 stop4h 17m
Delta
Fri 10/307:30 am
JAX
- SGF
1 stop4h 41m
Delta
Deal found 5/19![Delta logo]()
$447
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:12 pm
SGF
- JAX
1 stop4h 47m
American Airlines
Mon 6/225:59 pm
JAX
- SGF
1 stop5h 41m
American Airlines
Deal found 5/18![American Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:40 am
SGF
- JAX
1 stop6h 18m
Delta
Sun 9/202:30 pm
JAX
- SGF
1 stop4h 35m
Delta
Deal found 5/19![Delta logo]()
$447
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/253:35 pm
STL
- JAX
Nonstop2h 00m
Southwest
Mon 6/292:15 pm
JAX
- STL
1 stop7h 05m
Southwest
Deal found 5/21![Southwest logo]()
$341
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/273:25 pm
COU
- JAX
1 stop5h 34m
United Airlines
Sat 7/44:55 pm
JAX
- COU
1 stop7h 38m
United Airlines
Deal found 5/20![United Airlines logo]()
$378
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:19 pm
COU
- JAX
1 stop5h 23m
American Airlines
Sun 6/215:50 am
JAX
- COU
1 stop6h 24m
American Airlines
Deal found 5/20![American Airlines logo]()
$493
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/153:35 pm
STL
- JAX
Nonstop2h 00m
Southwest
Wed 6/178:25 am
JAX
- STL
Nonstop2h 10m
Southwest
Deal found 5/20![Southwest logo]()
$352
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/63:25 pm
COU
- JAX
1 stop5h 34m
United Airlines
Sat 6/136:42 pm
JAX
- COU
1 stop5h 51m
United Airlines
Deal found 5/21![United Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/103:25 pm
COU
- JAX
1 stop5h 34m
United Airlines
Sat 6/136:42 pm
JAX
- COU
1 stop5h 51m
United Airlines
Deal found 5/21![United Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:10 am
MCI
- JAX
1 stop7h 05m
Southwest
Mon 7/275:35 am
JAX
- MCI
1 stop4h 50m
Southwest
Deal found 5/18![Southwest logo]()
$381
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/98:00 am
COU
- JAX
1 stop5h 27m
United Airlines
Sat 6/134:47 pm
JAX
- COU
1 stop7h 46m
United Airlines
Deal found 5/21![United Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:50 am
MCI
- JAX
1 stop6h 45m
Southwest
Fri 7/106:55 am
JAX
- MCI
2 stops9h 30m
Southwest
Deal found 5/21![Southwest logo]()
$386
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:00 am
COU
- JAX
2 stops11h 08m
United Airlines
Wed 6/176:42 pm
JAX
- COU
1 stop5h 51m
United Airlines
Deal found 5/21![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:15 am
MCI
- JAX
1 stop5h 45m
Southwest
Tue 6/162:20 pm
JAX
- MCI
1 stop6h 00m
Southwest
Deal found 5/18![Southwest logo]()
$391
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/21:53 pm
JLN
- JAX
1 stop6h 53m
United Airlines
Sun 9/136:40 am
JAX
- JLN
1 stop7h 38m
United Airlines
Deal found 5/22![United Airlines logo]()
$429
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:30 pm
MCI
- JAX
1 stop4h 35m
Southwest
Tue 6/166:45 pm
JAX
- MCI
1 stop5h 40m
Southwest
Deal found 5/19![Southwest logo]()
$391
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/31:53 pm
JLN
- JAX
1 stop6h 53m
United Airlines
Sun 9/63:07 pm
JAX
- JLN
1 stop9h 37m
United Airlines
Deal found 5/21![United Airlines logo]()
$437
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:10 am
MCI
- JAX
2 stops7h 10m
Southwest
Mon 8/173:50 pm
JAX
- MCI
2 stops7h 45m
Southwest
Deal found 5/18![Southwest logo]()
$403
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/11:03 pm
MCI
- JAX
1 stop7h 56m
United Airlines
Tue 7/76:24 am
JAX
- MCI
2 stops10h 36m
United Airlines
Deal found 5/17![United Airlines logo]()
$440
Last-minute flights from Missouri to JacksonvilleDiscover last-minute flight deals from Missouri to Jacksonville. Data last updated May 22, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Jacksonville. Data last updated May 22, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:27 pm
STL
- JAX
2 stops14h 11m
Multiple Airlines
Tue 6/96:28 pm
JAX
- STL
1 stop15h 19m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:16 pm
MCI
- JAX
1 stop22h 17m
Frontier
Fri 6/196:28 pm
JAX
- MCI
1 stop23h 53m
Frontier
Deal found 5/18![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:06 pm
STL
- JAX
1 stop23h 27m
Frontier
Mon 6/226:28 pm
JAX
- STL
1 stop24h 02m
Frontier
Deal found 5/18![Frontier logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:06 pm
STL
- JAX
1 stop23h 27m
Frontier
Thu 6/186:28 pm
JAX
- STL
1 stop15h 24m
Frontier
Deal found 5/18![Frontier logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:06 pm
STL
- JAX
1 stop23h 27m
Frontier
Fri 6/266:28 pm
JAX
- STL
1 stop15h 24m
Frontier
Deal found 5/19![Frontier logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/225:06 pm
STL
- JAX
1 stop23h 27m
Frontier
Tue 6/306:28 pm
JAX
- STL
1 stop15h 24m
Frontier
Deal found 5/21![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:06 pm
STL
- JAX
1 stop23h 27m
Frontier
Sun 6/286:28 pm
JAX
- STL
1 stop15h 24m
Frontier
Deal found 5/19![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:16 pm
MCI
- JAX
1 stop22h 17m
Frontier
Tue 6/306:28 pm
JAX
- MCI
1 stop23h 53m
Frontier
Deal found 5/17![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:06 pm
STL
- JAX
2 stops14h 32m
Multiple Airlines
Sun 6/286:28 pm
JAX
- STL
1 stop15h 24m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:31 pm
STL
- JAX
1 stop22h 02m
Frontier
Sun 6/286:28 pm
JAX
- STL
1 stop15h 24m
Frontier
Deal found 5/19![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:31 pm
STL
- JAX
1 stop22h 02m
Frontier
Mon 6/296:28 pm
JAX
- STL
1 stop24h 02m
Frontier
Deal found 5/21![Frontier logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:31 pm
STL
- JAX
1 stop22h 02m
Frontier
Sun 7/56:28 pm
JAX
- STL
1 stop15h 29m
Frontier
Deal found 5/18![Frontier logo]()
$121
One-way flights from Missouri to JacksonvilleSearch for one-way flight options from Missouri to Jacksonville. Find affordable one-way fares based on user searches. Data last updated May 22, 2026.
Search for one-way flight options from Missouri to Jacksonville. Find affordable one-way fares based on user searches. Data last updated May 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:31 pm
STL
- JAX
1 stop22h 02m
Frontier
Deal found 5/19![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:06 pm
STL
- JAX
1 stop23h 27m
Frontier
Deal found 5/20![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:16 pm
MCI
- JAX
1 stop22h 17m
Frontier
Deal found 5/21![Frontier logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:06 pm
STL
- JAX
1 stop23h 27m
Frontier
Deal found 5/21![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:06 pm
STL
- JAX
1 stop23h 27m
Frontier
Deal found 5/21![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:16 pm
MCI
- JAX
1 stop22h 17m
Frontier
Deal found 5/21![Frontier logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:06 pm
STL
- JAX
1 stop23h 27m
Frontier
Deal found 5/20![Frontier logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/146:31 pm
STL
- JAX
1 stop22h 02m
Frontier
Deal found 5/17![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/34:52 pm
STL
- JAX
1 stop23h 41m
Frontier
Deal found 5/18![Frontier logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/135:06 pm
STL
- JAX
1 stop23h 27m
Frontier
Deal found 5/20![Frontier logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:31 pm
STL
- JAX
1 stop22h 02m
Frontier
Deal found 5/21![Frontier logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/134:57 pm
STL
- JAX
1 stop23h 37m
Frontier
Deal found 5/21![Frontier logo]()
$100
Find flight deals from Missouri to Jacksonville
Keep the following information in mind while searching for Missouri to Jacksonville flight deals. Data was last updated May 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $121 (Kiwi.com) |
One-way from | $63 (Kiwi.com) |
Popular in | May |
Cheapest in | September |
Average price | $367 |
Good round-trip deal | $347 or less |
Good one-way deal | $218 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Jacksonville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from Missouri to Jacksonville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbiaJacksonville
COU - JAX
COUJAX
Columbia Regional
Sat 6/27
5:19 pm-11:42 pm
1 stop5h 23m
Jacksonville
Sat 7/11
6:11 pm-9:52 pm
1 stop4h 41m
$298
St. LouisJacksonville
STL - JAX
STLJAX
Lambert-St Louis
Mon 6/22
3:35 pm-10:35 pm
1 stop6h 00m
Jacksonville
Tue 6/30
8:25 am-9:35 am
Nonstop2h 10m
$300
St. LouisJacksonville
STL - JAX
STLJAX
Lambert-St Louis
Mon 8/17
2:05 pm-5:05 pm
Nonstop2h 00m
Jacksonville
Mon 8/24
7:50 am-11:35 am
1 stop4h 45m
$303
St. LouisJacksonville
STL - JAX
STLJAX
Lambert-St Louis
Thu 8/20
2:20 pm-10:00 pm
1 stop6h 40m
Jacksonville
Fri 8/21
7:50 am-11:35 am
1 stop4h 45m
$311
St. LouisJacksonville
STL - JAX
STLJAX
Lambert-St Louis
Fri 7/10
7:08 am-1:45 pm
1 stop5h 37m
Jacksonville
Mon 7/13
7:09 pm-11:53 pm
1 stop5h 44m
$325
St. LouisJacksonville
STL - JAX
STLJAX
Lambert-St Louis
Fri 6/19
2:30 pm-9:35 pm
1 stop6h 05m
Jacksonville
Mon 6/22
7:15 pm-10:50 pm
1 stop4h 35m
$325
St. LouisJacksonville
STL - JAX
STLJAX
Lambert-St Louis
Fri 8/14
3:45 pm-9:05 pm
1 stop4h 20m
Jacksonville
Tue 8/18
6:15 am-7:25 am
Nonstop2h 10m
$332
JoplinJacksonville
JLN - JAX
JLNJAX
Joplin
Fri 6/5
1:57 pm-9:40 pm
1 stop6h 43m
Jacksonville
Tue 6/9
7:20 am-1:22 pm
1 stop7h 02m
$334
JoplinJacksonville
JLN - JAX
JLNJAX
Joplin
Thu 6/4
1:57 pm-9:40 pm
1 stop6h 43m
Jacksonville
Mon 6/8
7:20 am-1:22 pm
1 stop7h 02m
$334
SpringfieldJacksonville
SGF - JAX
SGFJAX
Springfield-Branson
Sat 8/22
7:30 am-8:54 pm
2 stops12h 24m
Jacksonville
Wed 8/26
11:51 am-9:52 pm
2 stops11h 01m
$340
Showing 1-10 of 57 resultsSorted by cheapest first
Best time to book a flight from Missouri to Jacksonville
Have a flexible travel schedule? Discover the best time to fly to Jacksonville from Missouri with our price prediction graph.
STL-JAX
MCI-JAX
COU-JAX
JLN-JAX
SGF-JAX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Jacksonville
USMO-JAX
STL-JAX
MCI-JAX
COU-JAX
JLN-JAX
What is the cheapest month to book a flight from Missouri to Jacksonville?
Currently, March is the cheapest month in which you can book a flight from Missouri to Jacksonville (average of $80). Flying from Missouri to Jacksonville in August is currently the most expensive (average of $199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to JAX?
Find hourly flight availability from Missouri to Jacksonville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 22, 2026.
It’s optimal to fly from Missouri to Jacksonville in the evening. By choosing this option you can save up to 23% on the cost of your flight, compared to a flight at noon.
How much does it cost to fly round-trip from Missouri to Jacksonville?
How far ahead should I book a flight from Missouri to Jacksonville?
The price you pay for your flight from Missouri to Jacksonville may vary depending on when you book. For the best chance of a lower fare, look to book 78 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Jacksonville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Jacksonville?
Book flights to Jacksonville if you plan to visit one of these locationsJacksonville Beach
Fernandina Beach
Orange Park
Kingsland
Waycross
Atlantic Beach
Yulee
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Missouri to Jacksonville
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Complete your trip
Complete your trip to Jacksonville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Jacksonville by cabin class
Find flights from Missouri to Jacksonville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Jacksonville
Explore flights to Jacksonville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 22, 2026.
Missouri and Jacksonville flights
Browse other Missouri and Jacksonville flight options. Last updated on May 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Jacksonville flights
Consider these flights traveling from Missouri to Jacksonville.
Top 6 airlines flying from Missouri to Jacksonville
Discover the top 6 airlines that operate flights from Missouri to Jacksonville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$80 | Average$111 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$168 | Average$363 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$211 | Average$369 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$214 | Average$357 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$238 | Average$357 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$251 | Average$326 | FlexibilityNo cancel fee | On-time62% |