$56+ Cheap flights from Jacksonville to St. Louis (JAX - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/6. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — STL
Sep 9 — Sep 161
Round-trip
1 adult, Economy
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Find cheap flights from Jacksonville to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Jacksonville to Lambert-St Louis are usually found in October or November, booked 52 days in advance, depart on a Friday or Wednesday and return on a Friday
Cheap flight deals from Jacksonville to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Jacksonville to St. LouisExplore the most affordable flight options available from Jacksonville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
Explore the most affordable flight options available from Jacksonville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:46 pm -
1 stop15h 54m
Mon 10/1910:35 am -
1 stop6h 16m
Deal found 8/8![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:46 pm -
1 stop15h 54m
Mon 10/1910:35 am -
1 stop6h 16m
Deal found 8/8![Frontier logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:46 pm -
1 stop15h 54m
Sun 10/1110:35 am -
1 stop6h 16m
Deal found 8/6![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:05 pm -
1 stop23h 17m
Wed 9/92:29 pm -
1 stop27h 32m
Deal found 8/5![Frontier logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:46 pm -
1 stop18h 24m
Mon 9/142:29 pm -
1 stop27h 32m
Deal found 8/9![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:05 pm -
1 stop23h 17m
Mon 9/76:17 pm -
1 stop22h 53m
Deal found 8/8![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:05 pm -
1 stop23h 17m
Mon 8/316:17 pm -
1 stop22h 53m
Deal found 8/6![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:46 pm -
2 stops25h 53m
Mon 10/2610:35 am -
1 stop6h 16m
Deal found 8/6![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:46 pm -
1 stop15h 54m
Mon 10/1910:35 am -
2 stops22h 05m
Deal found 8/8![Multiple Airlines logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:46 pm -
2 stops40h 46m
Mon 9/212:29 pm -
1 stop27h 32m
Deal found 8/5![Frontier logo]()
$177
Best flights from Jacksonville to St. LouisDiscover carefully curated flight deals from Jacksonville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
Discover carefully curated flight deals from Jacksonville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:00 pm -
Nonstop2h 10m
Mon 9/145:45 am -
1 stop5h 35m
Deal found 8/9![Southwest logo]()
$237
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:05 am -
1 stop6h 46m
Sun 10/256:00 am -
1 stop6h 22m
Deal found 8/5![Delta logo]()
$328
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:16 pm -
1 stop7h 27m
Wed 9/308:43 am -
1 stop4h 19m
Deal found 8/10![American Airlines logo]()
$357
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:30 am -
1 stop5h 32m
Sun 9/66:55 am -
2 stops12h 59m
Deal found 8/7![United Airlines logo]()
$358
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:00 pm -
Nonstop2h 10m
Mon 9/212:05 pm -
Nonstop2h 00m
Deal found 8/5![Southwest logo]()
$279
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:50 am -
1 stop4h 45m
Mon 9/2811:20 am -
Nonstop2h 00m
Deal found 8/6![Southwest logo]()
$297
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:45 am -
2 stops8h 40m
Wed 9/98:00 am -
2 stops7h 45m
Deal found 8/5![Southwest logo]()
$299
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:35 am -
2 stops11h 30m
Sun 10/44:35 pm -
1 stop4h 35m
Deal found 8/10![Southwest logo]()
$310
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:15 am -
2 stops10h 35m
Sat 9/129:00 am -
2 stops8h 00m
Deal found 8/9![Southwest logo]()
$322
Last-minute flights from Jacksonville to St. LouisDiscover last-minute flight deals from Jacksonville to St. Louis. Data last updated August 10, 2026 and is based on user searches.
Discover last-minute flight deals from Jacksonville to St. Louis. Data last updated August 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:05 pm -
1 stop23h 17m
Mon 8/316:17 pm -
1 stop22h 53m
Deal found 8/6![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:05 pm -
1 stop23h 17m
Wed 9/92:29 pm -
1 stop27h 32m
Deal found 8/5![Frontier logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:05 pm -
1 stop23h 17m
Mon 9/76:17 pm -
1 stop22h 53m
Deal found 8/8![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:05 pm -
1 stop23h 17m
Mon 9/76:17 pm -
2 stops18h 16m
Deal found 8/8![Multiple Airlines logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:05 pm -
1 stop23h 17m
Sat 9/128:10 pm -
2 stops45h 51m
Deal found 8/6![Frontier logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:46 pm -
1 stop18h 24m
Mon 9/142:29 pm -
1 stop27h 32m
Deal found 8/9![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:46 pm -
1 stop18h 24m
Mon 9/142:29 pm -
2 stops24h 57m
Deal found 8/9![Multiple Airlines logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:46 pm -
2 stops40h 46m
Mon 9/212:29 pm -
1 stop27h 32m
Deal found 8/5![Frontier logo]()
$177
One-way flights from Jacksonville to St. LouisSearch for one-way flight options from Jacksonville to St. Louis. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
Search for one-way flight options from Jacksonville to St. Louis. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:05 pm -
1 stop23h 17m
Deal found 8/8![Frontier logo]()
$56
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:46 pm -
1 stop15h 54m
Deal found 8/6![Frontier logo]()
$57
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:46 pm -
1 stop18h 24m
Deal found 8/7![Frontier logo]()
$58
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:46 pm -
1 stop15h 54m
Deal found 8/5![Frontier logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:46 pm -
1 stop14h 54m
Deal found 8/9![Frontier logo]()
$66
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:46 pm -
1 stop15h 54m
Deal found 8/6![Frontier logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:05 pm -
1 stop23h 17m
Deal found 8/7![Frontier logo]()
$73
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:46 pm -
1 stop15h 54m
Deal found 8/9![Frontier logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:05 pm -
1 stop23h 17m
Deal found 8/5![Frontier logo]()
$75
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:05 pm -
1 stop19h 05m
Deal found 8/6![Frontier logo]()
$80
Find flight deals from Jacksonville to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Jacksonville (JAX) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $105 (Kiwi.com) |
One-way from | $56 (Kiwi.com) |
Popular in | March |
Cheapest in | October |
Average price | $357 |
Good round-trip deal | $349 or less |
Good one-way deal | $242 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Jacksonville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Jacksonville to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Thu 9/10
2:00 pm-3:10 pm
Nonstop2h 10m
Lambert-St Louis
Mon 9/14
5:45 am-12:20 pm
1 stop5h 35m
$237
Quickest round-trip
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Mon 9/14
2:00 pm-3:10 pm
Nonstop2h 10m
Lambert-St Louis
Mon 9/21
2:05 pm-5:05 pm
Nonstop2h 00m
$279
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Fri 9/25
7:50 am-11:35 am
1 stop4h 45m
Lambert-St Louis
Mon 9/28
11:20 am-2:20 pm
Nonstop2h 00m
$297
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Wed 9/2
6:45 am-2:25 pm
2 stops8h 40m
Lambert-St Louis
Wed 9/9
8:00 am-4:45 pm
2 stops7h 45m
$299
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Sat 10/3
5:35 am-4:05 pm
2 stops11h 30m
Lambert-St Louis
Sun 10/4
4:35 pm-10:10 pm
1 stop4h 35m
$310
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Sat 9/5
11:15 am-8:50 pm
2 stops10h 35m
Lambert-St Louis
Sat 9/12
9:00 am-6:00 pm
2 stops8h 00m
$322
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Thu 10/22
5:05 am-10:51 am
1 stop6h 46m
Lambert-St Louis
Sun 10/25
6:00 am-1:22 pm
1 stop6h 22m
$328
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Thu 9/24
5:16 pm-11:43 pm
1 stop7h 27m
Lambert-St Louis
Wed 9/30
8:43 am-2:02 pm
1 stop4h 19m
$357
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Thu 9/3
7:30 am-12:02 pm
1 stop5h 32m
Lambert-St Louis
Sun 9/6
6:55 am-8:54 pm
2 stops12h 59m
$358
Cheapest one-way
JacksonvilleSt. Louis
JAX Jacksonville - STL Lambert-St Louis
JAXSTL
Jacksonville
Mon 11/2
6:46 pm-9:40 am
1 stop15h 54m
$69
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Jacksonville to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Jacksonville to St. Louis in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Jacksonville-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Jacksonville-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Jacksonville-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Jacksonville-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Jacksonville-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Jacksonville to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Jacksonville with our price prediction graph.
JAX-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Jacksonville to St. Louis
How far ahead should I book a flight from Jacksonville to St. Louis?
The best time to book flights from Jacksonville to St. Louis is 50 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Jacksonville to St. Louis?
Currently, October is the cheapest month in which you can book a flight from Jacksonville to St. Louis (average of $309). Flying from Jacksonville to St. Louis in March is currently the most expensive (average of $443). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from JAX to STL?
Find hourly flight availability from Jacksonville to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 10, 2026.
When flying from Jacksonville to St. Louis, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 15% versus a flight in the morning.
What is the cheapest day to fly from Jacksonville to St. Louis?
Use this chart to determine the cheapest time to fly round-trip from Jacksonville to St. Louis. Price data was last updated on August 8, 2026.
Travelers seeking maximum savings on their Jacksonville to St. Louis flight should consider departing on Monday at noon when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
The best insider tips for Jacksonville to St. Louis flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Jacksonville to St. Louis trip
Our travel experts
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated August 10, 2026.
Read through reviews of airlines operating flights from Jacksonville to St. Louis, such as Southwest,Delta, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from Jacksonville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
Fairview Heights
O'Fallon
Fenton
Swansea
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Farmington
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Alternative routes for Jacksonville to St. Louis
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Jacksonville and St. Louis flights
Browse other Jacksonville and St. Louis flight options. Last updated on August 10, 2026.
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Top 3 airlines flying from Jacksonville to St. Louis
Discover the top 3 airlines that operate flights from Jacksonville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$214 | Average$362 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$237 | Average$365 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$255 | Average$376 | FlexibilityNo cancel fee | On-time71% |