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$71+ Cheap flights from Jacksonville to St. Louis (JAX - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — STL
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheapflights Tip: The best prices from Jacksonville to Lambert-St Louis are usually found in July or August, booked 78 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from Jacksonville to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Jacksonville (JAX) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$151
(United Airlines)

One-way from

$71
(United Airlines)

Popular in

March

Cheapest in

July

Average price

$281

Good round-trip deal

$298 or less

Good one-way deal

$192 or less
From Jacksonville to Lambert-St Louis
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One-way flight from Jacksonville to Lambert-St Louis
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Highest demand for flights based on searches. 6% potential increase in price ($21 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Jacksonville to Lambert-St Louis.
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Price to beat on a one-way flight from Jacksonville to Lambert-St Louis.
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Find flight deals from Jacksonville to St. Louis

Cheapest flights from Jacksonville to St. Louis
Explore the most affordable flight options available from Jacksonville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2411:54 amJAX - STL
1 stop8h 03mUnited Airlines
Mon 10/276:15 amSTL - JAX
1 stop8h 19mUnited Airlines
Deal found 9/15$151
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/245:57 pmJAX - STL
1 stop6h 57mAmerican Airlines
Mon 10/274:34 pmSTL - JAX
1 stop5h 04mAmerican Airlines
Deal found 9/14$159
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/95:10 amJAX - STL
1 stop3h 55mDelta
Sun 10/126:00 amSTL - JAX
1 stop3h 22mDelta
Deal found 9/15$177
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/96:03 pmJAX - STL
1 stop17h 34mFrontier
Sun 10/1210:17 amSTL - JAX
1 stop23h 35mFrontier
Deal found 9/15$217
This Booking.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/143:20 pmJAX - STL
2 stops18h 47mFrontier
Sun 11/1611:17 amSTL - JAX
1 stop4h 06mFrontier
Deal found 9/16$223
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:20 amJAX - STL
1 stop5h 36mAmerican Airlines
Wed 12/246:00 pmSTL - JAX
1 stop5h 11mAmerican Airlines
Deal found 9/13$224
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:10 amJAX - STL
1 stop7h 13mUnited Airlines
Sun 12/78:00 amSTL - JAX
2 stops11h 10mUnited Airlines
Deal found 9/15$226
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/138:15 pmJAX - STL
Nonstop2h 10mSouthwest
Mon 10/208:15 pmSTL - JAX
Nonstop1h 55mSouthwest
Deal found 9/13$237
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/267:22 amJAX - STL
1 stop7h 22mAmerican Airlines
Wed 10/2912:51 pmSTL - JAX
1 stop5h 13mAmerican Airlines
Deal found 9/14$238
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/138:11 pmJAX - STL
1 stop4h 30mDelta
Mon 10/206:00 amSTL - JAX
1 stop3h 22mDelta
Deal found 9/13$247
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/248:15 pmJAX - STL
Nonstop2h 10mSouthwest
Mon 10/278:15 pmSTL - JAX
Nonstop1h 55mSouthwest
Deal found 9/15$254
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:10 amJAX - STL
1 stop4h 54mDelta
Sun 11/307:02 pmSTL - JAX
1 stop4h 04mDelta
Deal found 9/15$257

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Jacksonville to St. Louis that are best for you.

Fly from

Jacksonville

Fly to

St. Louis

Route

Depart

Return

Price

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Fri 10/24

5:57 pm-11:54 pm

1 stop6h 57m

Lambert-St Louis

Mon 10/27

4:34 pm-10:38 pm

1 stop5h 04m

$159

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Sat 11/1

1:12 pm-3:55 pm

1 stop3h 43m

Lambert-St Louis

Sat 11/8

10:30 am-2:56 pm

1 stop3h 26m

$177

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Wed 1/7

5:30 am-10:50 am

1 stop6h 20m

Lambert-St Louis

Sun 1/11

7:05 pm-12:01 am

1 stop3h 56m

$177

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Fri 1/9

7:30 am-10:50 am

1 stop4h 20m

Lambert-St Louis

Sat 1/10

6:30 am-1:20 pm

1 stop5h 50m

$177

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Thu 1/8

11:50 am-4:55 pm

1 stop6h 05m

Lambert-St Louis

Sun 1/11

6:30 am-1:20 pm

1 stop5h 50m

$177

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Thu 1/8

7:30 am-10:50 am

1 stop4h 20m

Lambert-St Louis

Sat 1/10

10:00 am-4:20 pm

1 stop5h 20m

$177

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Thu 2/19

8:10 pm-11:40 pm

1 stop4h 30m

Lambert-St Louis

Mon 2/23

12:00 pm-8:48 pm

1 stop7h 48m

$177

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Sat 10/11

8:54 am-2:43 pm

1 stop6h 49m

Lambert-St Louis

Mon 10/13

6:00 am-12:21 pm

1 stop5h 21m

$177

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Fri 1/9

7:30 am-10:50 am

1 stop4h 20m

Lambert-St Louis

Sun 1/11

7:30 am-2:13 pm

1 stop5h 43m

$177

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Fri 1/9

6:30 am-10:50 am

1 stop5h 20m

Lambert-St Louis

Mon 1/12

7:05 pm-12:01 am

1 stop3h 56m

$177

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 23 results
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The best insider tips for Jacksonville to St. Louis flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your Jacksonville to St. Louis trip
Airports
JAX

JAX offers quick screening times at TSA and easy check-in, making it convenient for early morning departures.

Read more about JAXby Matt Meltzer
STL

Use the MetroLink light rail for a convenient and economical way to reach downtown St. Louis from STL.

Read more about STLby Taryn White
Our travel experts
Matt Meltzer

Matt Meltzer

Expert on JAX

Matt Meltzer

Matt Meltzer

Matt Meltzer has been a travel writer for over a decade, covering U.S. domestic locations and hotels for Thrillist, Fifty Grande, Matador Network, Conde Nast Traveler, and other top publications. He's won multiple travel journalism awards from the Society of American Travel Writers and North American Travel Journalists Association, and currently resides in South Florida.

Read more
Taryn White

Taryn White

Expert on STL

Taryn White

Taryn White

Taryn White is a freelance travel writer, digital creator, and travel advisor who has visited nearly 100 countries and all 50 states. She’s familiar with many airports and enjoys beach hopping, boutique hotels, spa experiences, and exploring local culture. Her work has appeared in Travel + Leisure, Condé Nast Traveler, National Geographic, Smithsonian Magazine, AFAR, and more.

Read more

Best time to book a flight from Jacksonville to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to St. Louis

How far ahead should I book a flight from Jacksonville to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Jacksonville to St. Louis. Price data was last updated on September 12, 2025.

The best time to book flights from Jacksonville to St. Louis is 29 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Jacksonville to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Jacksonville to St. Louis (average of $311). Flying from Jacksonville to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from JAX to STL?

Find hourly flight availability from Jacksonville to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from Jacksonville to St. Louis, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 25% versus a flight at noon.

What is the cheapest day to fly from Jacksonville to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Jacksonville to St. Louis. Price data was last updated on September 14, 2025.

Travelers seeking maximum savings on their Jacksonville to St. Louis flight should consider departing on Monday evenings when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from Jacksonville to St. Louis, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,957 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Jacksonville to St. Louis?

    If you book a flight from Jacksonville to St. Louis, you will be flying from Jacksonville to Lambert-St Louis. Flights to Lambert-St Louis (STL) from Jacksonville (JAX) take 2h 10m for a nonstop flight. There is 1 flight from Jacksonville to St. Louis per day from 3 airlines.

  • How popular is this Jacksonville to St. Louis flight route?

    The Jacksonville to Lambert-St Louis flight path was viewed by 20 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Jacksonville to St. Louis?

    American Airlines and Delta can get you from Jacksonville to St. Louis in just under 3h 43m. Your travel time can differ by up to 3h 14m. There are 753 mi between Jacksonville and St. Louis. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Jacksonville to St. Louis round-trip?

    Delta, at $199, was found to be the cheapest airline from Jacksonville to St. Louis.Alternate airlines to your destination round-trip include Southwest and American Airlines. Delta is 38% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest flights from Jacksonville to St. Louis?

    On average you can expect to pay $292 for a flight from Jacksonville to St. Louis. The cheapest flight overall is $104 while the most popular route, (Jacksonville - Lambert-St Louis) is currently priced at $151.

  • Can I find deals for flights from Jacksonville to St. Louis that include hotel bookings?

    Yes. In addition to deals on Jacksonville to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to St. Louis.

  • Can I find deals for business class flights from Jacksonville to St. Louis?

    Yes. Cheapflights offers flight deals from Jacksonville to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Jacksonville to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Jacksonville to St. Louis (average of $311). Flying from Jacksonville to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

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Top 3 airlines flying from Jacksonville to St. Louis

Discover the top 3 airlines that operate flights from Jacksonville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$199Average$302FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$216Average$324FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$218Average$331FlexibilityNo cancel feeOn-time71%

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