HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
St. Louis

$74+ Cheap flights from Jacksonville to St. Louis (JAX - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — STL
dic. 6 — dic. 131
sáb. 12/6
sáb. 12/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Jacksonville to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Jacksonville to Lambert-St Louis are usually found in July or August, booked 90 days in advance, depart on a Tuesday or Friday and return on a Friday

Find flight deals from Jacksonville to St. Louis

Cheapest flights from Jacksonville to St. Louis
Explore the most affordable flight options available from Jacksonville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 6, 2025.

This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/67:18 amJAX - STL
1 stop6h 55mAmerican Airlines
mar. 12/92:11 pmSTL - JAX
1 stop6h 55mAmerican Airlines
Deal found 11/4$179
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/76:06 pmJAX - STL
1 stop4h 22mAmerican Airlines
dom. 12/1411:34 amSTL - JAX
1 stop7h 45mAmerican Airlines
Deal found 11/4$249
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/611:25 amJAX - STL
Nonstop2h 20mSouthwest
mar. 12/96:10 pmSTL - JAX
Nonstop1h 55mSouthwest
Deal found 11/4$257
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/316:00 amJAX - STL
1 stop5h 50mAmerican Airlines
jue. 1/15:30 amSTL - JAX
1 stop5h 26mAmerican Airlines
Deal found 11/6$262
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/266:05 pmJAX - STL
1 stop6h 50mAmerican Airlines
mié. 12/317:05 amSTL - JAX
1 stop6h 48mAmerican Airlines
Deal found 11/5$280
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/16:03 pmJAX - STL
1 stop7h 02mAmerican Airlines
mié. 12/39:30 amSTL - JAX
1 stop5h 05mAmerican Airlines
Deal found 11/6$290
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/46:10 pmJAX - STL
Nonstop2h 20mSouthwest
dom. 12/77:50 amSTL - JAX
Nonstop2h 00mSouthwest
Deal found 11/5$294

Cheap flight deals from Jacksonville to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Jacksonville (JAX) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated noviembre 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$179
(American Airlines)

One-way from

$74
(Trip.com)

Popular in

March

Cheapest in

July

Average price

$344

Good round-trip deal

$327 or less

Good one-way deal

$173 or less
Provider with most accurate pricing for Jacksonville-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jacksonville-Lambert-St Louis flights.
Search Deals
From Jacksonville to Lambert-St Louis
Search Deals
One-way flight from Jacksonville to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Jacksonville to Lambert-St Louis.
Search Deals
Price to beat on a one-way flight from Jacksonville to Lambert-St Louis.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
Use the filters below to find and compare flights from Jacksonville to St. Louis that are best for you.

Fly from

Jacksonville

Fly to

St. Louis

Route

Depart

Return

Price

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

sáb. 12/6

7:18 am-1:13 pm

1 stop6h 55m

Lambert-St Louis

mar. 12/9

2:11 pm-10:06 pm

1 stop6h 55m

$179

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

dom. 12/7

6:06 pm-9:28 pm

1 stop4h 22m

Lambert-St Louis

dom. 12/14

11:34 am-8:19 pm

1 stop7h 45m

$249

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

sáb. 12/6

11:25 am-12:45 pm

Nonstop2h 20m

Lambert-St Louis

mar. 12/9

6:10 pm-9:05 pm

Nonstop1h 55m

$257

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

mié. 12/31

12:50 pm-4:00 pm

1 stop4h 10m

Lambert-St Louis

jue. 1/1

7:00 am-4:04 pm

1 stop8h 04m

$262

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

sáb. 12/6

4:37 pm-9:40 pm

1 stop6h 03m

Lambert-St Louis

mar. 12/9

10:00 am-8:10 pm

2 stops9h 10m

$267

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

jue. 2/19

5:49 pm-8:41 pm

1 stop3h 52m

Lambert-St Louis

lun. 2/23

10:13 am-4:44 pm

1 stop5h 31m

$281

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

jue. 12/4

6:10 pm-7:30 pm

Nonstop2h 20m

Lambert-St Louis

dom. 12/7

7:50 am-10:50 am

Nonstop2h 00m

$294

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

jue. 12/11

8:08 pm-11:42 pm

1 stop4h 34m

Lambert-St Louis

dom. 12/14

5:12 pm-10:04 pm

1 stop3h 52m

$299

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

mié. 12/3

5:05 am-8:24 am

1 stop4h 19m

$122

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

mié. 12/10

8:10 am-12:15 pm

1 stop5h 05m

$122

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/6

Showing 1-10 of 17 results
1
2

Compare providers for flights from Jacksonville to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Jacksonville to St. Louis in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Jacksonville-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Jacksonville-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Jacksonville-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Jacksonville-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Jacksonville-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Jacksonville to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to St. Louis

How far ahead should I book a flight from Jacksonville to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Jacksonville to St. Louis. Price data was last updated on October 31, 2025.

The best time to book flights from Jacksonville to St. Louis is 29 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Jacksonville to St. Louis?

Currently, April is the cheapest month in which you can book a flight from Jacksonville to St. Louis (average of $139). Flying from Jacksonville to St. Louis in November is currently the most expensive (average of $250). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from JAX to STL?

Find hourly flight availability from Jacksonville to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 6, 2025.

When flying from Jacksonville to St. Louis, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 14% versus a flight at noon.

What is the cheapest day to fly from Jacksonville to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Jacksonville to St. Louis. Price data was last updated on November 2, 2025.

Travelers seeking maximum savings on their Jacksonville to St. Louis flight should consider departing on Tuesday mornings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

The best insider tips for Jacksonville to St. Louis flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your Jacksonville to St. Louis trip
Airports
JAX

JAX offers quick screening times at TSA and easy check-in, making it convenient for early morning departures.

Read more about JAXby Matt Meltzer
STL

Use the MetroLink light rail for a convenient and economical way to reach downtown St. Louis from STL.

Read more about STLby Taryn White
Our travel experts
Matt Meltzer

Matt Meltzer

Expert on JAX

Matt Meltzer

Matt Meltzer

Matt Meltzer has been a travel writer for over a decade, covering U.S. domestic locations and hotels for Thrillist, Fifty Grande, Matador Network, Conde Nast Traveler, and other top publications. He's won multiple travel journalism awards from the Society of American Travel Writers and North American Travel Journalists Association, and currently resides in South Florida.

Read more
Taryn White

Taryn White

Expert on STL

Taryn White

Taryn White

Taryn White is a freelance travel writer, digital creator, and travel advisor who has visited nearly 100 countries and all 50 states. She’s familiar with many airports and enjoys beach hopping, boutique hotels, spa experiences, and exploring local culture. Her work has appeared in Travel + Leisure, Condé Nast Traveler, National Geographic, Smithsonian Magazine, AFAR, and more.

Read more

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated noviembre 6, 2025.
Read through reviews of airlines operating flights from Jacksonville to St. Louis, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Food

7.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Food

7.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,001 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Food

7.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,040 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Food

7.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Jacksonville to St. Louis?

    If you book a flight from Jacksonville to St. Louis, you will be flying from Jacksonville to Lambert-St Louis. Flights to Lambert-St Louis (STL) from Jacksonville (JAX) take 2h 15m for a nonstop flight. There are 2 flights from Jacksonville to St. Louis per day from 3 airlines.

  • How popular is this Jacksonville to St. Louis flight route?

    The Jacksonville to Lambert-St Louis flight path was viewed by 22 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Jacksonville to St. Louis?

    American Airlines, Southwest, and United Airlines can get you from Jacksonville to St. Louis in just under 2h 20m. Your travel time can differ by up to 4h 35m. There are 753 mi between Jacksonville and St. Louis. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Jacksonville to St. Louis round-trip?

    Delta, at $194, was found to be the cheapest airline from Jacksonville to St. Louis.Alternate airlines to your destination round-trip include Southwest and American Airlines. Delta is 39% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Jacksonville to St. Louis one-way?

    The cheapest airlines for a one-way flight from Jacksonville to St. Louis are Delta ($122), United Airlines ($122), and Southwest ($122).

  • What are the cheapest flights from Jacksonville to St. Louis?

    On average you can expect to pay $311 for a flight from Jacksonville to St. Louis. The cheapest flight overall is $135 while the most popular route, (Jacksonville - Lambert-St Louis) is currently priced at $249.

  • Can I find deals for flights from Jacksonville to St. Louis that include hotel bookings?

    Yes. In addition to deals on Jacksonville to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to St. Louis.

  • Can I find deals for business class flights from Jacksonville to St. Louis?

    Yes. Cheapflights offers flight deals from Jacksonville to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Jacksonville to St. Louis?

    Currently, April is the cheapest month in which you can book a flight from Jacksonville to St. Louis (average of $139). Flying from Jacksonville to St. Louis in November is currently the most expensive (average of $250). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Jacksonville to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
Orlando to St. Louis flights
Tampa to St. Louis flights
Orlando to Kansas City flights
Tampa to Kansas City flights
Miami to Kansas City flights
Miami to St. Louis flights
West Palm Beach to St. Louis flights
Fort Lauderdale to St. Louis flights
Fort Myers to St. Louis flights
Sarasota to St. Louis flights
West Palm Beach to Kansas City flights
Fort Lauderdale to Kansas City flights
Fort Myers to Kansas City flights
Pensacola to Springfield flights
Pensacola to Kansas City flights
Sarasota to Kansas City flights
Melbourne to St. Louis flights
West Palm Beach to Springfield flights
Jacksonville to Kansas City flights
Orlando to Springfield flights
Panama City to St. Louis flights
Jacksonville to Springfield flights
Miami to Springfield flights
Orlando to Columbia flights
Fort Myers to Springfield flights
Tampa to Springfield flights
Pensacola to St. Louis flights
Pensacola to Columbia flights
Valparaiso to Kansas City flights
Valparaiso to St. Louis flights
Panama City to Kansas City flights
Daytona Beach to St. Louis flights
Fort Lauderdale to Springfield flights
Tallahassee to Kansas City flights
Fort Myers to Joplin flights
Sarasota to Joplin flights
Sarasota to Springfield flights
Orlando to Joplin flights
Tallahassee to St. Louis flights
Gainesville to Kansas City flights
Fort Lauderdale to Columbia flights
Tallahassee to Springfield flights
Daytona Beach to Kansas City flights
Melbourne to Springfield flights
Jacksonville to Joplin flights
West Palm Beach to Columbia flights
Valdosta to Kansas City flights
Panama City to Springfield flights
Tampa to Columbia flights

Top 3 airlines flying from Jacksonville to St. Louis

Discover the top 3 airlines that operate flights from Jacksonville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$194Average$280FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$214Average$311FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$218Average$318FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.