$49+ Cheap flights from Indiana to St. Louis (STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/31. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
Mar 15 — Mar 221
1 adult, Economy
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Find cheap flights from Indiana to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Indiana to St. Louis
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Cheapest flights from Indiana to St. LouisExplore the most affordable flight options available from Indiana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.
Explore the most affordable flight options available from Indiana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:15 am
MDW
- STL
Nonstop1h 20m
Southwest
Wed 3/1110:30 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/10![Southwest logo]()
$97
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/109:33 pm
ORD
- STL
Nonstop1h 26m
United Airlines
Wed 3/118:17 am
STL
- ORD
Nonstop1h 33m
United Airlines
Deal found 2/10![United Airlines logo]()
$97
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/510:34 pm
ORD
- STL
Nonstop1h 14m
American Airlines
Sun 3/86:00 am
STL
- ORD
Nonstop1h 28m
American Airlines
Deal found 2/12![American Airlines logo]()
$98
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:15 pm
ORD
- STL
1 stop5h 10m
Southwest
Wed 3/117:30 am
STL
- ORD
1 stop5h 20m
Southwest
Deal found 2/10![Southwest logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:16 pm
MDW
- STL
1 stop18h 33m
Frontier
Mon 3/92:09 pm
STL
- MDW
1 stop5h 38m
Frontier
Deal found 2/10![Frontier logo]()
$132
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Wed 3/115:40 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/10![Southwest logo]()
$134
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:42 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Wed 3/118:17 am
STL
- ORD
Nonstop1h 33m
United Airlines
Deal found 2/10![United Airlines logo]()
$134
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:23 am
ORD
- STL
Nonstop1h 22m
American Airlines
Wed 5/137:05 am
STL
- ORD
Nonstop1h 31m
American Airlines
Deal found 2/10![American Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/227:31 pm
IND
- STL
1 stop12h 20m
Frontier
Wed 2/258:17 pm
STL
- IND
1 stop21h 14m
Frontier
Deal found 2/10![Frontier logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:05 am
ORD
- STL
1 stop6h 44m
Frontier
Mon 3/92:09 pm
STL
- ORD
1 stop18h 14m
Frontier
Deal found 2/10![Frontier logo]()
$146
This Southwest deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:00 am
MDW
- STL
1 stop5h 30m
Southwest
Thu 3/264:05 pm
STL
- MDW
1 stop4h 15m
Southwest
Deal found 2/12![Southwest logo]()
$154
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/114:15 pm
ORD
- STL
1 stop5h 10m
Southwest
Wed 3/187:30 am
STL
- ORD
1 stop5h 20m
Southwest
Deal found 2/11![Southwest logo]()
$154
Best flights from Indiana to St. LouisDiscover carefully curated flight deals from Indiana to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 13, 2026.
Discover carefully curated flight deals from Indiana to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 13, 2026.
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:30 am
MDW
- STL
Nonstop1h 10m
Southwest
Tue 3/174:00 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 2/10![Southwest logo]()
$97
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:30 pm
ORD
- STL
Nonstop1h 26m
United Airlines
Sat 4/46:30 am
STL
- ORD
Nonstop1h 29m
United Airlines
Deal found 2/12![United Airlines logo]()
$134
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:30 am
ORD
- STL
1 stop5h 39m
Delta
Tue 3/105:21 pm
STL
- ORD
1 stop6h 33m
Delta
Deal found 2/12![Delta logo]()
$157
This Frontier deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:55 am
ORD
- STL
1 stop8h 17m
Frontier
Mon 5/49:55 pm
STL
- ORD
1 stop8h 52m
Frontier
Deal found 2/10![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:16 pm
MDW
- STL
1 stop18h 33m
Multiple Airlines
Mon 3/94:51 pm
STL
- MDW
2 stops20h 11m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$173
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/113:20 pm
MDW
- STL
1 stop4h 40m
Southwest
Wed 3/188:50 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 2/11![Southwest logo]()
$107
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/277:10 pm
AZO
- STL
1 stop5h 25m
American Airlines
Tue 3/37:05 am
STL
- AZO
2 stops10h 31m
American Airlines
Deal found 2/12![American Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/72:10 pm
MDW
- STL
Nonstop1h 15m
Southwest
Wed 5/135:35 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/10![Southwest logo]()
$134
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:49 am
ORD
- STL
1 stop5h 53m
Delta
Tue 4/211:45 pm
STL
- ORD
1 stop6h 55m
Delta
Deal found 2/11![Delta logo]()
$157
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:42 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Wed 3/255:00 am
STL
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/12![United Airlines logo]()
$157
This Southwest deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:15 am
MDW
- STL
Nonstop1h 20m
Southwest
Thu 3/264:45 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 2/12![Southwest logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:27 pm
IND
- STL
1 stop12h 24m
Frontier
Wed 3/1811:32 am
STL
- IND
1 stop22h 44m
Frontier
Deal found 2/10![Frontier logo]()
$164
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/177:10 am
ORD
- STL
1 stop5h 48m
Delta
Tue 3/175:21 pm
STL
- ORD
1 stop6h 33m
Delta
Deal found 2/10![Delta logo]()
$157
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Wed 3/115:40 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/10![Southwest logo]()
$134
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:33 pm
ORD
- STL
Nonstop1h 26m
United Airlines
Mon 3/167:40 am
STL
- ORD
Nonstop1h 29m
United Airlines
Deal found 2/12![United Airlines logo]()
$171
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:59 pm
ORD
- STL
1 stop5h 59m
Delta
Wed 3/256:32 am
STL
- ORD
1 stop6h 45m
Delta
Deal found 2/12![Delta logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:07 pm
CVG
- STL
1 stop18h 44m
Frontier
Tue 3/33:49 pm
STL
- CVG
1 stop28h 36m
Frontier
Deal found 2/9![Frontier logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:00 am
IND
- STL
2 stops18h 19m
Multiple Airlines
Wed 3/1811:32 am
STL
- IND
1 stop22h 44m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$194
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:40 pm
ORD
- STL
Nonstop1h 28m
United Airlines
Sat 5/910:00 am
STL
- ORD
Nonstop1h 33m
United Airlines
Deal found 2/9![United Airlines logo]()
$171
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/129:00 am
ORD
- STL
1 stop4h 05m
Delta
Tue 5/125:15 pm
STL
- ORD
1 stop5h 13m
Delta
Deal found 2/10![Delta logo]()
$167
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:45 am
MDW
- STL
1 stop5h 15m
Southwest
Sat 4/1110:35 am
STL
- MDW
1 stop6h 25m
Southwest
Deal found 2/10![Southwest logo]()
$154
This Expedia deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/297:20 am
CVG
- STL
1 stop27h 29m
Frontier
Tue 3/3111:27 am
STL
- CVG
1 stop9h 28m
Frontier
Deal found 2/11![Frontier logo]()
$195
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:40 pm
ORD
- STL
1 stop4h 40m
Southwest
Sat 4/1110:55 am
STL
- ORD
1 stop4h 35m
Southwest
Deal found 2/10![Southwest logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/262:43 pm
IND
- STL
2 stops17h 07m
Multiple Airlines
Wed 4/298:13 pm
STL
- IND
1 stop14h 04m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$231
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/275:47 am
DAY
- STL
1 stop7h 46m
American Airlines
Tue 3/35:12 am
STL
- DAY
1 stop5h 27m
American Airlines
Deal found 2/11![American Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/289:32 pm
IND
- STL
2 stops34h 19m
Frontier
Wed 3/1811:32 am
STL
- IND
1 stop22h 44m
Frontier
Deal found 2/10![Frontier logo]()
$215
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:46 pm
CVG
- STL
1 stop5h 00m
American Airlines
Wed 5/612:25 pm
STL
- CVG
1 stop8h 15m
American Airlines
Deal found 2/11![American Airlines logo]()
$261
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/139:00 am
MDW
- STL
Nonstop1h 15m
Southwest
Mon 4/134:40 pm
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/10![Southwest logo]()
$171
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:32 am
DAY
- STL
1 stop6h 11m
American Airlines
Sat 2/288:00 am
STL
- DAY
2 stops8h 26m
American Airlines
Deal found 2/11![American Airlines logo]()
$264
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:15 pm
SBN
- STL
1 stop3h 44m
United Airlines
Mon 3/27:41 am
STL
- SBN
1 stop3h 57m
United Airlines
Deal found 2/9![United Airlines logo]()
$244
Last-minute flights from Indiana to St. LouisDiscover last-minute flight deals from Indiana to St. Louis. Data last updated February 13, 2026 and is based on user searches.
Discover last-minute flight deals from Indiana to St. Louis. Data last updated February 13, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/227:31 pm
IND
- STL
1 stop12h 20m
Frontier
Wed 2/258:17 pm
STL
- IND
1 stop21h 14m
Frontier
Deal found 2/10![Frontier logo]()
$139
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:18 am
ORD
- STL
Nonstop1h 23m
American Airlines
Sun 3/86:00 am
STL
- ORD
Nonstop1h 28m
American Airlines
Deal found 2/12![American Airlines logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:16 pm
MDW
- STL
1 stop18h 33m
Frontier
Mon 3/92:09 pm
STL
- MDW
1 stop5h 38m
Frontier
Deal found 2/10![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/512:44 pm
ORD
- STL
1 stop11h 15m
Multiple Airlines
Mon 3/92:09 pm
STL
- ORD
1 stop18h 14m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:05 am
ORD
- STL
1 stop6h 44m
Frontier
Mon 3/92:09 pm
STL
- ORD
1 stop18h 14m
Frontier
Deal found 2/10![Frontier logo]()
$146
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Wed 3/115:40 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/10![Southwest logo]()
$134
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:42 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Wed 3/118:17 am
STL
- ORD
Nonstop1h 33m
United Airlines
Deal found 2/10![United Airlines logo]()
$134
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:15 am
MDW
- STL
Nonstop1h 20m
Southwest
Wed 3/1110:30 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/10![Southwest logo]()
$97
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/109:33 pm
ORD
- STL
Nonstop1h 26m
United Airlines
Wed 3/118:17 am
STL
- ORD
Nonstop1h 33m
United Airlines
Deal found 2/10![United Airlines logo]()
$97
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:15 pm
ORD
- STL
1 stop5h 10m
Southwest
Wed 3/117:30 am
STL
- ORD
1 stop5h 20m
Southwest
Deal found 2/10![Southwest logo]()
$117
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/114:15 pm
ORD
- STL
1 stop5h 10m
Southwest
Wed 3/187:30 am
STL
- ORD
1 stop5h 20m
Southwest
Deal found 2/11![Southwest logo]()
$154
This Southwest deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:00 am
MDW
- STL
1 stop5h 30m
Southwest
Thu 3/264:05 pm
STL
- MDW
1 stop4h 15m
Southwest
Deal found 2/12![Southwest logo]()
$154
One-way flights from Indiana to St. LouisSearch for one-way flight options from Indiana to St. Louis. Find affordable one-way fares based on user searches. Data last updated February 13, 2026.
Search for one-way flight options from Indiana to St. Louis. Find affordable one-way fares based on user searches. Data last updated February 13, 2026.
This Southwest deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/319:05 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 2/13![Southwest logo]()
$49
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:40 pm
ORD
- STL
Nonstop1h 28m
United Airlines
Deal found 2/11![United Airlines logo]()
$49
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:30 pm
ORD
- STL
Nonstop1h 16m
American Airlines
Deal found 2/12![American Airlines logo]()
$50
This Southwest deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:40 pm
ORD
- STL
1 stop5h 15m
Southwest
Deal found 2/13![Southwest logo]()
$59
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:35 am
MDW
- STL
2 stops6h 20m
Southwest
Deal found 2/10![Southwest logo]()
$64
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:40 pm
ORD
- STL
1 stop7h 20m
Southwest
Deal found 2/10![Southwest logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:05 am
MDW
- STL
1 stop5h 44m
Frontier
Deal found 2/11![Frontier logo]()
$67
This Trip.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/221:07 pm
CVG
- STL
1 stop18h 44m
Frontier
Deal found 2/9![Frontier logo]()
$67
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:05 am
MDW
- STL
1 stop7h 14m
Frontier
Deal found 2/10![Frontier logo]()
$68
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/812:16 pm
IND
- STL
1 stop26h 03m
Frontier
Deal found 2/10![Frontier logo]()
$68
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:59 am
ORD
- STL
Nonstop1h 25m
American Airlines
Deal found 2/13![American Airlines logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/11:07 pm
CVG
- STL
1 stop18h 44m
Frontier
Deal found 2/9![Frontier logo]()
$72
Find flight deals from Indiana to St. Louis
Keep the following information in mind while searching for Indiana to St. Louis flight deals. Data was last updated February 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $97 (Southwest) |
One-way from | $49 (Southwest) |
Popular in | September |
Cheapest in | November |
Average price | $460 |
Cheapflights Fare Finder
Customize your flight search to find flights from Indiana to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Indiana to St. Louis that are best for you.
Fly from
Indiana
Fly to
St. Louis
Route
Depart
Return
Price
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Tue 3/17
10:30 am-11:40 am
Nonstop1h 10m
Lambert-St Louis
Tue 3/17
4:00 pm-5:05 pm
Nonstop1h 05m
$97
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Wed 3/11
3:20 pm-8:00 pm
1 stop4h 40m
Lambert-St Louis
Wed 3/18
8:50 pm-9:55 pm
Nonstop1h 05m
$107
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Wed 4/1
9:30 pm-10:56 pm
Nonstop1h 26m
Lambert-St Louis
Sat 4/4
6:30 am-7:59 am
Nonstop1h 29m
$134
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Thu 5/7
2:10 pm-3:25 pm
Nonstop1h 15m
Lambert-St Louis
Wed 5/13
5:35 am-6:45 am
Nonstop1h 10m
$134
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Wed 3/25
8:15 am-9:35 am
Nonstop1h 20m
Lambert-St Louis
Thu 3/26
4:45 pm-5:50 pm
Nonstop1h 05m
$134
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Mon 3/9
11:15 am-12:30 pm
Nonstop1h 15m
Lambert-St Louis
Wed 3/11
5:40 am-6:50 am
Nonstop1h 10m
$134
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Wed 4/8
7:45 am-1:00 pm
1 stop5h 15m
Lambert-St Louis
Sat 4/11
10:35 am-5:00 pm
1 stop6h 25m
$154
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Wed 4/8
2:40 pm-7:20 pm
1 stop4h 40m
Lambert-St Louis
Sat 4/11
10:55 am-3:30 pm
1 stop4h 35m
$154
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Tue 3/10
5:30 am-11:09 am
1 stop5h 39m
Lambert-St Louis
Tue 3/10
5:21 pm-11:54 pm
1 stop6h 33m
$157
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Tue 4/14
10:49 am-4:42 pm
1 stop5h 53m
Lambert-St Louis
Tue 4/21
1:45 pm-8:40 pm
1 stop6h 55m
$157
Showing 1-10 of 60 results
Best time to book a flight from Indiana to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Indiana with our price prediction graph.
MDW-STL
ORD-STL
CVG-STL
IND-STL
AZO-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Indiana to St. Louis
USIN-STL
MDW-STL
ORD-STL
CVG-STL
IND-STL
What is the cheapest month to book a flight from Indiana to St. Louis?
Currently, September is the cheapest month in which you can book a flight from Indiana to St. Louis (average of $164). Flying from Indiana to St. Louis in October is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Indiana to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
Chesterfield
Alton
Farmington
Festus
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Indiana to St. Louis
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Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Indiana to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Indiana and St. Louis flights
Browse other Indiana and St. Louis flight options. Last updated on February 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 13, 2026.
Indiana to St. Louis flights
Consider these flights traveling from Indiana to St. Louis.
Top 3 airlines flying from Indiana to St. Louis
Discover the top 3 airlines that operate flights from Indiana to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$196 | Average$357 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$198 | Average$266 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$213 | Average$366 | FlexibilityNo cancel fee | On-time69% |