In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What is the cheapest time of day to fly from FLO to STL?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Florence, South Carolina to St. Louis as you normally would.

Can I find deals for flights from Florence to St. Louis that include hotel bookings?

Yes. In addition to deals on Florence to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Florence to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to St. Louis.

Can I find deals for business class flights from Florence to St. Louis?

Yes. Cheapflights offers flight deals from Florence to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$417+ Flights from Florence, SC to St. Louis

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Cheap flight deals from Florence to St. Louis

Round-trip from	$417 (American Airlines)

From Florence to Lambert-St Louis

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Cheapest flights from Florence to St. Louis
Explore the most affordable flight options available from Florence to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Thu 7/175:07 amFLO - STL

1 stop4h 08mAmerican Airlines

Mon 7/215:15 amSTL - FLO

1 stop4h 32mAmerican Airlines

Deal found 7/2

$417

Best flights from Florence to St. Louis
Discover carefully curated flight deals from Florence to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 3, 2025.

Thu 7/175:07 amFLO - STL

1 stop4h 08mAmerican Airlines

Mon 7/215:15 amSTL - FLO

1 stop4h 32mAmerican Airlines

Deal found 7/2

$417

Last-minute flights from Florence to St. Louis
Discover last-minute flight deals from Florence to St. Louis. Data last updated July 3, 2025 and is based on user searches.

Thu 7/175:07 amFLO - STL

1 stop4h 08mAmerican Airlines

Mon 7/215:15 amSTL - FLO

1 stop4h 32mAmerican Airlines

Deal found 7/2

$417

Cheapflights Fare Finder

Use the filters below to find and compare flights from Florence to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Thu 7/17

5:07 am-8:15 am

1 stop4h 08m

Lambert-St Louis

Mon 7/21

5:15 am-10:47 am

1 stop4h 32m

$417

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from Florence to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Florence with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to St. Louis

What is the cheapest month to book a flight from Florence, South Carolina to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Florence, South Carolina to St. Louis (average of $311). Flying from Florence, South Carolina to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Florence to St. Louis, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

2.0

Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

American Airlines

7.2

Good

10,000 reviews

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

2.0

Mediocre

Andrew,May 2025

LAX - MIA

Related info for your journey

Can I find deals for flights from Florence to St. Louis that include hotel bookings?
Yes. In addition to deals on Florence to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Florence to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to St. Louis.
Can I find deals for business class flights from Florence to St. Louis?
Yes. Cheapflights offers flight deals from Florence to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Florence, South Carolina to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Florence, South Carolina to St. Louis (average of $311). Flying from Florence, South Carolina to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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$417+ Cheap flights from Florence, SC to St. Louis (FLO - STL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/17. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Florence to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Florence to St. Louis

Round-trip from

Find flight deals from Florence to St. Louis

Cheapest flights from Florence to St. LouisExplore the most affordable flight options available from Florence to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Explore the most affordable flight options available from Florence to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Florence to St. Louis that are best for you.

Best time to book a flight from Florence to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Florence with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Florence to St. Louis

What is the cheapest month to book a flight from Florence, South Carolina to St. Louis?

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Florence to St. Louis, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Florence to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

Can I find deals for flights from Florence to St. Louis that include hotel bookings?

How can I find direct flights from Florence to St. Louis?

Can I find deals for business class flights from Florence to St. Louis?

What is the cheapest month to book a flight from Florence, South Carolina to St. Louis?

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Cheapest flights from Florence to St. Louis
Explore the most affordable flight options available from Florence to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.