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St. Louis

$213+ Cheap flights from Biloxi, MS to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — STL
Jul 29 — Aug 51
Wed 7/29
Wed 8/5
1 adult, Economy
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Cheap flight deals from Biloxi to St. Louis

Cheapest flights from Biloxi to St. Louis
Explore the most affordable flight options available from Biloxi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 29, 2026.

This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:00 pm
GPT
-
STL
2 stops8h 59m
United Airlines
Tue 9/18:35 am
STL
-
GPT
1 stop7h 37m
United Airlines
Deal found 6/25$346
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:30 am
GPT
-
STL
1 stop6h 04m
Delta
Sun 7/59:21 am
STL
-
GPT
1 stop3h 46m
Delta
Deal found 6/25$379
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:04 am
GPT
-
STL
2 stops9h 29m
American Airlines
Sun 7/55:32 am
STL
-
GPT
1 stop5h 23m
American Airlines
Deal found 6/25$426
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:19 pm
GPT
-
STL
1 stop5h 26m
United Airlines
Tue 7/148:35 am
STL
-
GPT
1 stop4h 50m
United Airlines
Deal found 6/25$509

Find flight deals from Biloxi to St. Louis

Keep the following information in mind while searching for Biloxi to St. Louis flight deals. Data was last updated June 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$346
(United Airlines)

One-way from

$213
(American Airlines)

Popular in

December

Cheapest in

March
Provider with most accurate pricing for Gulfport Biloxi Regional-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Lambert-St Louis flights.
Search Deals
From Biloxi to Lambert-St Louis
Search Deals
One-way flight from Biloxi to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($120 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($33 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 29, 2026.
Use the filters below to find and compare flights from Biloxi to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Sat 8/29

2:00 pm-10:59 pm

2 stops8h 59m

Lambert-St Louis

Tue 9/1

8:35 am-4:12 pm

1 stop7h 37m

$346
Cheapest one-way

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Wed 7/22

6:35 pm-11:58 pm

1 stop5h 23m

$213
Quickest one-way

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Wed 8/12

5:45 pm-10:40 pm

1 stop4h 55m

$213

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Wed 7/22

2:00 pm-11:44 pm

2 stops9h 44m

$258

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Wed 8/12

2:00 pm-10:59 pm

2 stops8h 59m

$285

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Tue 7/14

5:57 pm-11:53 pm

1 stop5h 56m

$368

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Tue 7/14

7:04 am-5:02 pm

2 stops9h 58m

$373

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Sun 7/5

5:19 pm-10:45 pm

1 stop5h 26m

$419

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Mon 7/6

5:19 pm-10:45 pm

1 stop5h 26m

$419

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Mon 7/6

8:21 am-5:37 pm

2 stops33h 16m

$455

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/26

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Best time to book a flight from Biloxi to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to St. Louis

What is the cheapest time of day to fly from B1L to STL?

Find hourly flight availability from Biloxi to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 29, 2026.

One of the essential ways to save on airfare from Biloxi to St. Louis is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 9% on airfare.

What is the cheapest day to fly from Biloxi to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Biloxi to St. Louis. Price data was last updated on June 27, 2026.

Travelers seeking maximum savings on their Biloxi to St. Louis flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated June 29, 2026.
Read through reviews of airlines operating flights from Biloxi to St. Louis, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,449 reviews

Boarding

8.1

Food

7.2

Crew

8.5

Overall

7.8

Entertainment

7.8

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.8
Good
8,449 reviews
Delta
7.8
Good
8,449 reviews

Boarding

8.1

Food

7.2

Crew

8.5

Overall

7.8

Entertainment

7.8

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,768 reviews
Delta
7.8
Good
8,449 reviews

Boarding

8.1

Food

7.2

Crew

8.5

Overall

7.8

Entertainment

7.8

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Biloxi to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Biloxi?

    If you book a flight to St. Louis from Biloxi, you will be flying to Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis. There are 0 flights from Biloxi to Lambert-St Louis per day from 4 different airlines.

  • How popular is this Biloxi to St. Louis flight route?

    This flight path from Biloxi to Lambert-St Louis was viewed by 10 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Biloxi to St. Louis?

    United Airlines can get you from Biloxi to St. Louis in just under 8h 59m. Your travel time can differ by up to . The distance between Biloxi and St. Louis is about 581 mi.

  • What are the cheapest flights from Biloxi to St. Louis?

    While on average a flight from Biloxi to St. Louis is generally $367, our data shows the cheapest flight currently is $132. When looking at the most popular route, (Gulfport Biloxi Regional - Lambert-St Louis), you can expect to pay $346 for that flight.

  • Can I find deals for flights from Biloxi to St. Louis that include hotel bookings?

    Yes. In addition to deals on Biloxi to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to St. Louis.

  • Can I find deals for business class flights from Biloxi to St. Louis?

    Yes. Cheapflights offers flight deals from Biloxi to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Alton
Farmington

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Top 4 airlines flying from Biloxi to St. Louis

Discover the top 4 airlines that operate flights from Biloxi to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$72Average$168FlexibilityNo cancel feeOn-time62%
DeltaCheapest$143Average$405FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$407FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$306Average$389FlexibilityNo cancel feeOn-time63%

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