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St. Louis

$125+ Cheap flights from Biloxi, MS to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/25. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — STL
May 30 — Jun 61
Sat 5/30
Sat 6/6
1 adult, Economy
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Cheap flight deals from Biloxi to St. Louis

Cheapest flights from Biloxi to St. Louis
Explore the most affordable flight options available from Biloxi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:39 pm
GPT
-
STL
1 stop6h 51m
American Airlines
Sat 5/165:20 am
STL
-
GPT
1 stop5h 13m
American Airlines
Deal found 4/27$285
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:02 pm
GPT
-
STL
1 stop5h 57m
Delta
Sun 5/245:20 pm
STL
-
GPT
1 stop4h 31m
Delta
Deal found 4/27$312
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:02 pm
GPT
-
STL
1 stop5h 57m
Delta
Sun 5/245:20 pm
STL
-
GPT
1 stop4h 31m
Delta
Deal found 4/29$317
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:00 am
GPT
-
STL
1 stop7h 16m
United Airlines
Thu 5/288:35 am
STL
-
GPT
1 stop7h 36m
United Airlines
Deal found 4/25$334
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:03 pm
GPT
-
STL
1 stop5h 56m
American Airlines
Sat 5/165:20 am
STL
-
GPT
1 stop5h 13m
American Airlines
Deal found 4/28$338
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:02 pm
GPT
-
STL
1 stop5h 57m
Delta
Sun 5/315:20 pm
STL
-
GPT
1 stop4h 31m
Delta
Deal found 4/28$339
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:57 am
GPT
-
STL
1 stop5h 04m
United Airlines
Wed 10/288:50 am
STL
-
GPT
1 stop4h 36m
United Airlines
Deal found 4/27$341
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:02 pm
GPT
-
STL
1 stop5h 57m
Delta
Mon 5/185:20 pm
STL
-
GPT
1 stop4h 31m
Delta
Deal found 4/29$342

Find flight deals from Biloxi to St. Louis

Keep the following information in mind while searching for Biloxi to St. Louis flight deals. Data was last updated April 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$285
(Delta)

One-way from

$125
(Kiwi.com)

Popular in

August

Cheapest in

June

Average price

$554
Provider with most accurate pricing for Gulfport Biloxi Regional-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Lambert-St Louis flights.
Search Deals
From Biloxi to Lambert-St Louis
Search Deals
One-way flight from Biloxi to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($21 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Biloxi to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Tue 5/12

12:39 pm-7:30 pm

1 stop6h 51m

Lambert-St Louis

Sat 5/16

5:20 am-10:33 am

1 stop5h 13m

$285

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Tue 5/19

6:02 pm-11:59 pm

1 stop5h 57m

Lambert-St Louis

Sun 5/24

5:20 pm-9:51 pm

1 stop4h 31m

$285

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Fri 5/22

6:02 pm-11:59 pm

1 stop5h 57m

Lambert-St Louis

Sun 5/24

9:13 am-2:04 pm

1 stop4h 51m

$285

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Tue 5/19

5:03 pm-10:59 pm

1 stop5h 56m

Lambert-St Louis

Sun 5/24

5:25 am-10:52 am

1 stop5h 27m

$317

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Thu 5/21

7:00 am-2:16 pm

1 stop7h 16m

Lambert-St Louis

Thu 5/28

8:35 am-4:11 pm

1 stop7h 36m

$334
Quickest round-trip

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Sat 10/24

11:57 am-5:01 pm

1 stop5h 04m

Lambert-St Louis

Wed 10/28

8:50 am-1:26 pm

1 stop4h 36m

$341
Cheapest one-way

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Thu 6/25

7:50 pm-12:09 am

1 stop28h 19m

$125
Quickest one-way

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Fri 6/26

5:56 pm-11:56 pm

1 stop6h 00m

$139

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Fri 6/26

5:31 pm-6:34 pm

2 stops25h 03m

$244

GulfportSt. Louis

GPT - STL

GPTSTL

Gulfport Biloxi Regional

Sun 5/17

7:50 pm-7:23 pm

2 stops23h 33m

$270

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/25

Sorted by cheapest first

Best time to book a flight from Biloxi to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to St. Louis

What is the cheapest time of day to fly from B1L to STL?

Find hourly flight availability from Biloxi to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2026.

One of the essential ways to save on airfare from Biloxi to St. Louis is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 14% on airfare.

What is the cheapest day to fly from Biloxi to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Biloxi to St. Louis. Price data was last updated on April 25, 2026.

Travelers seeking maximum savings on their Biloxi to St. Louis flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Biloxi to St. Louis?

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated April 30, 2026.
Read through reviews of airlines operating flights from Biloxi to St. Louis, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,463 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Overall

7.9

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,463 reviews
Delta
7.9
Good
8,463 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Overall

7.9

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,681 reviews
Delta
7.9
Good
8,463 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Overall

7.9

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Biloxi to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Biloxi?

    If you book a flight to St. Louis from Biloxi, you will be flying to Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis. There are 0 flights from Biloxi to Lambert-St Louis per day from 4 different airlines.

  • How popular is this Biloxi to St. Louis flight route?

    This flight path from Biloxi to Lambert-St Louis was viewed by 5 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Biloxi to St. Louis?

    American Airlines and Delta can get you from Biloxi to St. Louis in just under 5h 57m. Your travel time can differ by up to 54m. The distance between Biloxi and St. Louis is about 581 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest flights from Biloxi to St. Louis?

    While on average a flight from Biloxi to St. Louis is generally $343, our data shows the cheapest flight currently is $107. When looking at the most popular route, (Gulfport Biloxi Regional - Lambert-St Louis), you can expect to pay $285 for that flight.

  • Can I find deals for flights from Biloxi to St. Louis that include hotel bookings?

    Yes. In addition to deals on Biloxi to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to St. Louis.

  • Can I find deals for business class flights from Biloxi to St. Louis?

    Yes. Cheapflights offers flight deals from Biloxi to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Biloxi to St. Louis

Discover the top 4 airlines that operate flights from Biloxi to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$72Average$168FlexibilityNo cancel feeOn-time62%
DeltaCheapest$143Average$359FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$410FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$270Average$387FlexibilityNo cancel feeOn-time63%

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