$107+ Cheap flights from St. Louis (STL) to Biloxi, MS
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MSY
Sep 25 — Oct 21
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Biloxi with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Biloxi
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to BiloxiExplore the most affordable flight options available from St. Louis to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
Explore the most affordable flight options available from St. Louis to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:11 pm -
1 stop6h 05m
Sun 9/65:31 am -
1 stop6h 44m
Deal found 8/23![American Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:53 am -
1 stop6h 19m
Tue 9/295:42 pm -
1 stop5h 00m
Deal found 8/25![American Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:11 pm -
1 stop6h 05m
Wed 9/96:22 pm -
1 stop5h 21m
Deal found 8/21![American Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:00 am -
1 stop6h 01m
Mon 10/196:05 pm -
1 stop5h 49m
Deal found 8/25![Delta logo]()
$315
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:43 am -
1 stop4h 57m
Mon 9/285:42 pm -
1 stop5h 00m
Deal found 8/22![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:43 am -
1 stop4h 57m
Tue 10/66:31 pm -
1 stop5h 11m
Deal found 8/25![American Airlines logo]()
$346
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:25 pm -
1 stop7h 05m
Sat 9/125:42 pm -
1 stop5h 00m
Deal found 8/24![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:15 am -
1 stop7h 03m
Wed 11/44:55 pm -
1 stop5h 31m
Deal found 8/24![United Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/23:25 pm -
1 stop7h 05m
Sat 9/512:45 pm -
1 stop4h 49m
Deal found 8/24![American Airlines logo]()
$357
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:15 am -
1 stop4h 57m
Sat 9/52:00 pm -
2 stops8h 59m
Deal found 8/24![United Airlines logo]()
$362
Best flights from St. Louis to BiloxiDiscover carefully curated flight deals from St. Louis to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
Discover carefully curated flight deals from St. Louis to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:11 pm -
1 stop6h 05m
Wed 9/96:22 pm -
1 stop5h 21m
Deal found 8/21![American Airlines logo]()
$310
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:15 am -
1 stop7h 03m
Wed 11/44:55 pm -
1 stop5h 31m
Deal found 8/25![United Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:15 am -
1 stop4h 57m
Sat 9/122:00 pm -
2 stops8h 59m
Deal found 8/24![United Airlines logo]()
$370
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:25 am -
2 stops8h 47m
Wed 9/92:00 pm -
2 stops8h 59m
Deal found 8/21![United Airlines logo]()
$395
Last-minute flights from St. Louis to BiloxiDiscover last-minute flight deals from St. Louis to Biloxi. Data last updated August 26, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Biloxi. Data last updated August 26, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/23:25 pm -
1 stop7h 05m
Sat 9/512:45 pm -
1 stop4h 49m
Deal found 8/24![American Airlines logo]()
$357
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:15 am -
1 stop4h 57m
Sat 9/52:00 pm -
2 stops8h 59m
Deal found 8/24![United Airlines logo]()
$362
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:11 pm -
1 stop6h 05m
Sun 9/65:31 am -
1 stop6h 44m
Deal found 8/23![American Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:11 pm -
1 stop6h 05m
Wed 9/96:22 pm -
1 stop5h 21m
Deal found 8/21![American Airlines logo]()
$310
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:25 am -
2 stops8h 47m
Sun 9/62:00 pm -
2 stops8h 59m
Deal found 8/22![United Airlines logo]()
$371
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:25 pm -
1 stop7h 05m
Sat 9/125:42 pm -
1 stop5h 00m
Deal found 8/24![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:15 am -
1 stop4h 57m
Sat 9/122:00 pm -
2 stops8h 59m
Deal found 8/24![United Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:43 am -
1 stop4h 57m
Sun 9/136:27 pm -
1 stop5h 14m
Deal found 8/25![American Airlines logo]()
$346
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:43 am -
1 stop4h 57m
Mon 9/285:42 pm -
1 stop5h 00m
Deal found 8/22![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:53 am -
1 stop6h 19m
Tue 9/295:42 pm -
1 stop5h 00m
Deal found 8/25![American Airlines logo]()
$295
One-way flights from St. Louis to BiloxiSearch for one-way flight options from St. Louis to Biloxi. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
Search for one-way flight options from St. Louis to Biloxi. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:44 pm -
2 stops24h 21m
Deal found 8/24![Multiple Airlines logo]()
$107
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:35 am -
1 stop6h 32m
Deal found 8/24![American Airlines logo]()
$218
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:00 am -
2 stops11h 08m
Deal found 8/24![United Airlines logo]()
$223
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:42 am -
1 stop4h 59m
Deal found 8/22![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:25 am -
2 stops12h 13m
Deal found 8/22![United Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:45 pm -
3 stops36h 56m
Deal found 8/22![Multiple Airlines logo]()
$386
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:25 am -
3 stops29h 59m
Deal found 8/21![United Airlines logo]()
$499
Find flight deals from St. Louis to Biloxi
Keep the following information in mind while searching for St. Louis to Biloxi flight deals. Data was last updated August 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $271 (American Airlines) |
One-way from | $107 (Kiwi.com) |
Popular in | December |
Cheapest in | January |
Average price | $318 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
Use the filters below to find and compare flights from St. Louis to Biloxi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
St. LouisGulfport
STL Lambert-St Louis - GPT Gulfport Biloxi Regional
STLGPT
Lambert-St Louis
Sat 9/5
5:11 pm-11:16 pm
1 stop6h 05m
Gulfport Biloxi Regional
Wed 9/9
6:22 pm-11:43 pm
1 stop5h 21m
$310
St. LouisGulfport
STL Lambert-St Louis - GPT Gulfport Biloxi Regional
STLGPT
Lambert-St Louis
Sat 10/31
6:15 am-1:18 pm
1 stop7h 03m
Gulfport Biloxi Regional
Wed 11/4
4:55 pm-10:26 pm
1 stop5h 31m
$351
St. LouisGulfport
STL Lambert-St Louis - GPT Gulfport Biloxi Regional
STLGPT
Lambert-St Louis
Tue 9/8
11:15 am-4:12 pm
1 stop4h 57m
Gulfport Biloxi Regional
Sat 9/12
2:00 pm-10:59 pm
2 stops8h 59m
$370
St. LouisGulfport
STL Lambert-St Louis - GPT Gulfport Biloxi Regional
STLGPT
Lambert-St Louis
Sat 9/5
7:25 am-4:12 pm
2 stops8h 47m
Gulfport Biloxi Regional
Wed 9/9
2:00 pm-10:59 pm
2 stops8h 59m
$395
Cheapest one-way
St. LouisGulfport
STL Lambert-St Louis - GPT Gulfport Biloxi Regional
STLGPT
Lambert-St Louis
Wed 11/11
6:44 pm-7:05 pm
2 stops24h 21m
$107
St. LouisGulfport
STL Lambert-St Louis - GPT Gulfport Biloxi Regional
STLGPT
Lambert-St Louis
Wed 11/11
5:00 am-4:08 pm
2 stops11h 08m
$223
St. LouisGulfport
STL Lambert-St Louis - GPT Gulfport Biloxi Regional
STLGPT
Lambert-St Louis
Sun 9/6
3:44 pm-8:53 pm
1 stop5h 09m
$369
Quickest one-way
St. LouisGulfport
STL Lambert-St Louis - GPT Gulfport Biloxi Regional
STLGPT
Lambert-St Louis
Sat 9/5
5:42 am-10:41 am
1 stop4h 59m
$369
St. LouisGulfport
STL Lambert-St Louis - GPT Gulfport Biloxi Regional
STLGPT
Lambert-St Louis
Sun 9/6
6:00 am-4:12 pm
2 stops10h 12m
$374
St. LouisGulfport
STL Lambert-St Louis - GPT Gulfport Biloxi Regional
STLGPT
Lambert-St Louis
Sat 9/5
7:25 am-7:38 pm
2 stops12h 13m
$374
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Biloxi
Have a flexible travel schedule? Discover the best time to fly to Biloxi from St. Louis with our price prediction graph.
STL-GPT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Biloxi
STL-B1L
STL-GPT
What is the cheapest time of day to fly from STL to B1L?
Find hourly flight availability from St. Louis to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 26, 2026.
When flying from St. Louis to Biloxi, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 8% versus a flight in the afternoon.
How much does it cost to fly round-trip from St. Louis to Biloxi?
Airfare is below average for this route at the moment.
St. Louis to Biloxi flights typically cost between $290 and $345 in September.The cheapest round-trip price found within the last 5 days was $271 on American Airlines (Sep 5-Sep 6).
Reviews of airlines servicing Biloxi
Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated August 26, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from St. Louis to Biloxi to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.8
Overall
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Comfort
7.8
Overall
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Comfort
7.8
Overall
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Biloxi by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from St. Louis to Biloxi, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Biloxi flights
Browse other St. Louis and Biloxi flight options. Last updated on August 26, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on August 26, 2026.
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St. Louis to Biloxi flights
Consider these flights traveling from St. Louis to Biloxi.
Top 6 airlines flying from St. Louis to Biloxi
Discover the top 6 airlines that operate flights from St. Louis to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$82 | Average$227 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$93 | Average$359 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$118 | Average$222 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$196 | Average$391 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$384 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$303 | Average$442 | FlexibilityNo cancel fee | On-time63% |