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Spartanburg

$51+ Cheap flights from Indiana to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
IND — CLT
Dec 4 — Dec 111
Thu 12/4
Thu 12/11
1 adult, Economy
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Cheap flight deals from Indiana to Spartanburg

Keep the following information in mind while searching for Indiana to Spartanburg flight deals. Data was last updated November 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$84
(Priceline)

One-way from

$51
(Frontier)

Popular in

March

Cheapest in

September

Average price

$376
Provider with most accurate pricing for Indianapolis-Charlotte Douglas flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Charlotte Douglas flights.
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From Indiana to Spartanburg
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One-way flight from Indiana to Spartanburg
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Highest demand for flights based on searches. 16% potential increase in price ($77 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Indiana to Spartanburg

Cheapest flights from Indiana to Spartanburg
Explore the most affordable flight options available from Indiana to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2025.

This Priceline deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:15 amORD - CLT
Nonstop2h 07mFrontier
Mon 12/83:07 pmCLT - ORD
1 stop9h 50mFrontier
Deal found 11/3$84
This Priceline deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:15 amORD - CLT
Nonstop2h 07mFrontier
Thu 12/119:17 amCLT - ORD
Nonstop2h 13mFrontier
Deal found 11/4$87
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:50 amORD - CLT
Nonstop2h 07mFrontier
Sun 12/712:57 pmCLT - ORD
Nonstop2h 13mFrontier
Deal found 11/4$89
This CheapOair deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:50 amORD - CLT
Nonstop2h 07mFrontier
Mon 12/812:52 pmCLT - ORD
Nonstop2h 13mFrontier
Deal found 11/2$90
This Frontier deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1511:51 amORD - CLT
Nonstop2h 05mFrontier
Mon 11/174:27 pmCLT - ORD
1 stop9h 32mFrontier
Deal found 11/2$95
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/203:37 pmORD - CLT
1 stop14h 41mFrontier
Thu 11/274:17 pmCLT - ORD
Nonstop2h 22mFrontier
Deal found 11/4$97
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/238:30 amORD - CLT
1 stop4h 32mFrontier
Thu 11/274:17 pmCLT - ORD
Nonstop2h 22mFrontier
Deal found 11/3$100
This Priceline deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/225:30 amORD - CLT
1 stop8h 14mFrontier
Thu 11/274:17 pmCLT - ORD
Nonstop2h 22mFrontier
Deal found 11/4$101
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1511:51 amORD - CLT
Nonstop2h 05mMultiple Airlines
Thu 11/206:00 amCLT - ORD
1 stop9h 31mMultiple Airlines
Deal found 11/2$103
This Frontier deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/188:00 amCVG - CLT
1 stop5h 32mFrontier
Wed 12/310:45 amCLT - CVG
1 stop6h 59mFrontier
Deal found 11/3$110
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/176:30 pmCVG - CLT
1 stop19h 02mFrontier
Thu 11/2010:47 amCLT - CVG
1 stop7h 13mFrontier
Deal found 11/3$119
This Priceline deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:05 amMDW - CLT
1 stop9h 22mFrontier
Mon 12/83:07 pmCLT - MDW
1 stop8h 11mFrontier
Deal found 11/3$124

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Indiana to Spartanburg that are best for you.

Fly from

Indiana

Fly to

Spartanburg

Route

Depart

Return

Price

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Mon 11/17

2:31 pm-11:08 pm

1 stop7h 37m

Charlotte Douglas

Thu 11/20

10:47 am-5:13 pm

1 stop7h 26m

$117

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Tue 12/2

6:19 pm-9:39 pm

Nonstop2h 20m

Charlotte Douglas

Tue 12/9

6:30 am-7:52 am

Nonstop2h 22m

$149

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sun 12/7

8:20 pm-11:10 pm

Nonstop1h 50m

Charlotte Douglas

Tue 12/9

6:10 am-7:15 am

Nonstop2h 05m

$151

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 12/11

2:15 pm-5:20 pm

Nonstop2h 05m

Charlotte Douglas

Tue 12/16

5:28 pm-6:54 pm

Nonstop2h 26m

$151

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sun 12/7

2:15 pm-5:20 pm

Nonstop2h 05m

Charlotte Douglas

Sat 12/13

5:28 pm-6:54 pm

Nonstop2h 26m

$151

IndianapolisCharlotte

IND - CLT

INDCLT

Indianapolis

Wed 1/21

1:28 pm-6:36 pm

1 stop5h 08m

Charlotte Douglas

Wed 1/28

7:31 pm-12:32 am

1 stop5h 01m

$154

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 12/4

11:25 am-5:40 pm

1 stop5h 15m

Charlotte Douglas

Sun 12/7

5:50 am-6:50 am

Nonstop2h 00m

$173

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 12/4

11:25 am-5:40 pm

1 stop5h 15m

Charlotte Douglas

Mon 12/8

6:10 am-7:15 am

Nonstop2h 05m

$173

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 1/29

2:18 pm-5:24 pm

Nonstop2h 06m

Charlotte Douglas

Sun 2/1

6:15 am-7:48 am

Nonstop2h 33m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 12/6

9:29 am-4:13 pm

1 stop5h 44m

Charlotte Douglas

Thu 12/11

9:33 am-12:34 pm

1 stop4h 01m

$180

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/2

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Spartanburg

What is the cheapest month to book a flight from Indiana to Spartanburg?

Currently, April is the cheapest month in which you can book a flight from Indiana to Spartanburg (average of $134). Flying from Indiana to Spartanburg in December is currently the most expensive (average of $226). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to SB1?

Find hourly flight availability from Indiana to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 4, 2025.

One of the essential ways to save on airfare from Indiana to Spartanburg is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 42% on airfare.

What is the cheapest day to fly from Indiana to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Indiana to Spartanburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Indiana to Spartanburg flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Indiana to Spartanburg

Explore weekly flight availability from Indiana to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 4, 2025.

The most flights from USIN to SB1 are scheduled on a Monday (6 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).

Related info for your journey

Find useful and relevant information for your journey from Indiana to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Indiana to Spartanburg flight route?

    Within the past month, 1 users have taken a look at flights from Indiana to Spartanburg.

  • How long is the flight from Indiana to Spartanburg?

    For as low as $151, United Airlines can have you in Spartanburg from Indiana in 1h 50m. Airlines will cover a distance of 583 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Indiana to Spartanburg one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $55. Southwest flights start at $70 while deals on American Airlines start at $70 one-way.

  • What are the most popular routes from Indiana to Spartanburg?

    When deciding which route to take from Indiana to Spartanburg consider Chicago O'Hare Intl - Charlotte Douglas, Chicago Midway - Charlotte Douglas or Cincinnati Cinci./N. Kentucky - Charlotte Douglas as they are the most popular.

  • What are the cheapest flights from Indiana to Spartanburg?

    Looking at all options, your cheapest flight can be booked for $118. While the most popular route (Chicago O'Hare Intl - Charlotte Douglas) can be booked for $99 on average, our data indicates $682 when flying from Indiana to Spartanburg.

  • Can I find deals for flights from Indiana to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Indiana to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Spartanburg.

  • Can I find deals for business class flights from Indiana to Spartanburg?

    Yes. Cheapflights offers flight deals from Indiana to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Spartanburg?

    Currently, April is the cheapest month in which you can book a flight from Indiana to Spartanburg (average of $134). Flying from Indiana to Spartanburg in December is currently the most expensive (average of $226). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indiana to Spartanburg

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Indiana to Spartanburg

Discover the top 6 airlines that operate flights from Indiana to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$108Average$176FlexibilityNo cancel feeOn-time65%
FrontierCheapest$110Average$190FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$140Average$404FlexibilityNo cancel feeOn-time71%
DeltaCheapest$196Average$339FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$198Average$382FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$200Average$395FlexibilityNo cancel feeOn-time63%

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