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South Dakota

$269+ Cheap flights from Mississippi to South Dakota

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — FSD
Feb 5 — Feb 121
Thu 2/5
Thu 2/12
1 adult, Economy
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Cheap flight deals from Mississippi to South Dakota

Keep the following information in mind while searching for Mississippi to South Dakota flight deals. Data was last updated January 6, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$269
(American Airlines)
Provider with most accurate pricing for Jackson-Evers Intl-Sioux Falls Joe Foss Field flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Sioux Falls Joe Foss Field flights.
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From Mississippi to South Dakota
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Find flight deals from Mississippi to South Dakota

Cheapest flights from Mississippi to South Dakota
Explore the most affordable flight options available from Mississippi to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 6, 2026.

This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:01 amMEM - FSD
1 stop6h 35mAmerican Airlines
Sun 3/11:26 pmFSD - MEM
1 stop5h 43mAmerican Airlines
Deal found 1/6$269
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1911:46 amMEM - FSD
1 stop7h 24mAmerican Airlines
Sun 2/221:26 pmFSD - MEM
1 stop5h 43mAmerican Airlines
Deal found 1/6$280
This Delta deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/215:50 amMEM - RAP
1 stop5h 23mDelta
Sun 1/254:10 pmRAP - MEM
1 stop5h 30mDelta
Deal found 1/5$309
This American Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/215:31 amGPT - FSD
1 stop7h 22mAmerican Airlines
Sun 1/255:35 pmFSD - GPT
1 stop5h 58mAmerican Airlines
Deal found 1/5$309
This United Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/217:00 amGPT - FSD
2 stops9h 37mUnited Airlines
Sun 1/257:30 amFSD - GPT
2 stops12h 18mUnited Airlines
Deal found 1/5$330
This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2212:06 pmBTR - RAP
2 stops9h 27mUnited Airlines
Thu 8/2712:50 pmRAP - BTR
2 stops8h 56mUnited Airlines
Deal found 1/6$348
This United Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:40 amMEM - RAP
1 stop7h 37mUnited Airlines
Sat 2/217:00 amRAP - MEM
1 stop6h 14mUnited Airlines
Deal found 1/5$349
This United Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/189:25 amBTR - FSD
2 stops11h 05mUnited Airlines
Tue 4/219:05 amFSD - BTR
2 stops12h 05mUnited Airlines
Deal found 1/5$360
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/216:00 amBTR - FSD
1 stop6h 53mAmerican Airlines
Sun 1/255:35 pmFSD - BTR
1 stop5h 21mAmerican Airlines
Deal found 1/6$369
This United Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/279:30 amBTR - RAP
2 stops12h 02mUnited Airlines
Sat 1/315:10 amRAP - BTR
2 stops9h 48mUnited Airlines
Deal found 1/5$370
This United Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/194:15 pmMEM - FSD
1 stop7h 29mUnited Airlines
Mon 2/231:40 pmFSD - MEM
1 stop6h 59mUnited Airlines
Deal found 1/5$370
This United Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/277:00 amJAN - RAP
2 stops9h 22mUnited Airlines
Sat 1/315:10 amRAP - JAN
2 stops9h 52mUnited Airlines
Deal found 1/5$370

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
Use the filters below to find and compare flights from Mississippi to South Dakota that are best for you.

Fly from

Mississippi

Fly to

South Dakota

Route

Depart

Return

Price

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Tue 1/27

5:50 am-10:22 am

1 stop4h 32m

Sioux Falls Joe Foss Field

Tue 2/3

4:18 pm-10:40 pm

1 stop6h 22m

$269

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Thu 2/26

5:08 am-11:42 am

1 stop6h 34m

Sioux Falls Joe Foss Field

Sun 3/1

7:42 pm-12:03 am

1 stop4h 21m

$269

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Thu 2/19

7:01 am-11:42 am

1 stop4h 41m

Sioux Falls Joe Foss Field

Sun 2/22

7:42 pm-12:03 am

1 stop4h 21m

$280

MemphisRapid City

MEM - RAP

MEMRAP

Memphis

Wed 1/21

5:50 am-10:13 am

1 stop5h 23m

Rapid City

Sun 1/25

4:10 pm-10:40 pm

1 stop5h 30m

$309

GulfportSioux Falls

GPT - FSD

GPTFSD

Gulfport Biloxi Regional

Wed 1/21

5:31 am-12:53 pm

1 stop7h 22m

Sioux Falls Joe Foss Field

Sun 1/25

5:35 pm-11:33 pm

1 stop5h 58m

$309

GulfportSioux Falls

GPT - FSD

GPTFSD

Gulfport Biloxi Regional

Wed 1/21

7:00 am-4:37 pm

2 stops9h 37m

Sioux Falls Joe Foss Field

Sun 1/25

7:30 am-7:48 pm

2 stops12h 18m

$330

MemphisRapid City

MEM - RAP

MEMRAP

Memphis

Wed 2/18

4:15 pm-8:44 pm

1 stop5h 29m

Rapid City

Sat 2/21

8:30 am-2:14 pm

1 stop4h 44m

$349

Baton RougeSioux Falls

BTR - FSD

BTRFSD

Baton Rouge Ryan

Sat 4/18

9:25 am-8:30 pm

2 stops11h 05m

Sioux Falls Joe Foss Field

Tue 4/21

7:39 am-7:37 pm

2 stops11h 58m

$360

Baton RougeSioux Falls

BTR - FSD

BTRFSD

Baton Rouge Ryan

Wed 1/21

6:00 am-12:53 pm

1 stop6h 53m

Sioux Falls Joe Foss Field

Sun 1/25

5:35 pm-10:56 pm

1 stop5h 21m

$369

Baton RougeRapid City

BTR - RAP

BTRRAP

Baton Rouge Ryan

Tue 1/27

3:30 pm-10:29 pm

2 stops7h 59m

Rapid City

Sat 1/31

5:10 am-3:58 pm

2 stops9h 48m

$370

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/5

Showing 1-10 of 30 results
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Best time to book a flight from Mississippi to South Dakota

Have a flexible travel schedule? Discover the best time to fly to South Dakota from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South Dakota
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Dakota

Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated January 6, 2026.
Get a feel of what it's like to fly with American Airlines from Mississippi to South Dakota by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,083 reviews

Overall

7.2

Boarding

7.5

Food

6.4

Entertainment

6.9

Comfort

7.2

Crew

8.0

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,083 reviews
American Airlines
7.2
Good
11,083 reviews

Overall

7.2

Boarding

7.5

Food

6.4

Entertainment

6.9

Comfort

7.2

Crew

8.0

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to South Dakota?

    Departing from Mississippi to South Dakota will take you 4h 32m. Airlines will cover a distance of 691 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Mississippi to South Dakota that include hotel bookings?

    Yes. In addition to deals on Mississippi to South Dakota flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South Dakota?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South Dakota.

  • Can I find deals for business class flights from Mississippi to South Dakota?

    Yes. Cheapflights offers flight deals from Mississippi to South Dakota by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Alternative routes for Mississippi to South Dakota

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Top airline flying from Mississippi to South Dakota

Discover the top airline that operate flights from Mississippi to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$828FlexibilityNo cancel feeOn-time71%

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