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South Dakota

$211+ Cheap flights from Mississippi to South Dakota

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/9. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — FSD
Apr 15 — Apr 221
Wed 4/15
Wed 4/22
1 adult, Economy
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Cheap flight deals from Mississippi to South Dakota

Cheapest flights from Mississippi to South Dakota
Explore the most affordable flight options available from Mississippi to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 16, 2026.

This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:40 am
MEM
-
FSD
1 stop7h 16m
American Airlines
Thu 5/71:41 pm
FSD
-
MEM
1 stop5h 17m
American Airlines
Deal found 3/16$304
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:47 pm
MEM
-
FSD
1 stop4h 57m
United Airlines
Sun 4/56:10 am
FSD
-
MEM
1 stop4h 44m
United Airlines
Deal found 3/12$309
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/37:00 am
MEM
-
FSD
1 stop5h 41m
American Airlines
Sun 4/52:06 pm
FSD
-
MEM
2 stops9h 45m
American Airlines
Deal found 3/12$314
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/275:38 am
MEM
-
FSD
1 stop7h 03m
American Airlines
Sun 3/291:26 pm
FSD
-
MEM
1 stop5h 43m
American Airlines
Deal found 3/12$319
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/22:16 pm
MEM
-
RAP
1 stop8h 30m
United Airlines
Fri 5/81:00 pm
RAP
-
MEM
1 stop6h 54m
United Airlines
Deal found 3/12$319
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:00 am
GPT
-
FSD
1 stop7h 56m
American Airlines
Sat 5/25:28 pm
FSD
-
GPT
1 stop5h 23m
American Airlines
Deal found 3/14$319
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:00 am
MEM
-
FSD
2 stops9h 47m
American Airlines
Mon 4/201:41 pm
FSD
-
MEM
2 stops10h 06m
American Airlines
Deal found 3/16$325
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:10 am
GPT
-
FSD
2 stops13h 20m
United Airlines
Sat 4/186:10 am
FSD
-
GPT
2 stops8h 03m
United Airlines
Deal found 3/11$329
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:30 am
MOB
-
RAP
2 stops12h 02m
United Airlines
Wed 8/2610:13 am
RAP
-
MOB
2 stops10h 16m
United Airlines
Deal found 3/12$339
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/102:00 pm
BTR
-
RAP
2 stops9h 28m
United Airlines
Wed 4/1512:00 pm
RAP
-
BTR
2 stops9h 45m
United Airlines
Deal found 3/13$349
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:40 am
MEM
-
RAP
1 stop5h 43m
American Airlines
Tue 4/211:08 pm
RAP
-
MEM
1 stop7h 17m
American Airlines
Deal found 3/15$349
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:55 pm
GPT
-
FSD
1 stop5h 45m
Delta
Tue 4/285:00 am
FSD
-
GPT
2 stops8h 54m
Delta
Deal found 3/15$354

Find flight deals from Mississippi to South Dakota

Keep the following information in mind while searching for Mississippi to South Dakota flight deals. Data was last updated March 16, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$304
(American Airlines)

One-way from

$211
(Delta)
Provider with most accurate pricing for Jackson-Evers Intl-Sioux Falls Joe Foss Field flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Sioux Falls Joe Foss Field flights.
Search Deals
From Mississippi to South Dakota
Search Deals
One-way flight from Mississippi to South Dakota
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
Use the filters below to find and compare flights from Mississippi to South Dakota that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Fri 3/27

5:38 am-12:41 pm

1 stop7h 03m

Sioux Falls Joe Foss Field

Sun 3/29

1:26 pm-7:09 pm

1 stop5h 43m

$319

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Thu 4/16

5:00 am-2:47 pm

2 stops9h 47m

Sioux Falls Joe Foss Field

Mon 4/20

1:41 pm-11:47 pm

2 stops10h 06m

$325

GulfportSioux Falls

GPT - FSD

GPTFSD

Gulfport Biloxi Regional

Fri 4/17

7:10 am-8:30 pm

2 stops13h 20m

Sioux Falls Joe Foss Field

Sat 4/18

6:10 am-2:13 pm

2 stops8h 03m

$329

MobileRapid City

MOB - RAP

MOBRAP

Mobile

Sat 8/22

9:30 am-5:08 pm

2 stops8h 38m

Rapid City

Wed 8/26

11:08 am-9:29 pm

2 stops9h 21m

$339

Baton RougeRapid City

BTR - RAP

BTRRAP

Baton Rouge Ryan

Fri 4/10

2:00 pm-10:28 pm

2 stops9h 28m

Rapid City

Tue 4/14

12:00 pm-9:10 pm

2 stops8h 10m

$349

Baton RougeRapid City

BTR - RAP

BTRRAP

Baton Rouge Ryan

Sat 4/11

5:00 am-3:40 pm

2 stops11h 40m

Rapid City

Wed 4/15

12:00 pm-10:45 pm

2 stops9h 45m

$349

MemphisRapid City

MEM - RAP

MEMRAP

Memphis

Thu 3/26

8:35 am-1:13 pm

1 stop5h 38m

Rapid City

Mon 3/30

12:00 pm-9:40 pm

2 stops8h 40m

$374

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Wed 4/8

6:45 pm-11:44 pm

1 stop4h 59m

Sioux Falls Joe Foss Field

Sat 4/11

3:10 pm-10:04 pm

1 stop6h 54m

$379

GulfportSioux Falls

GPT - FSD

GPTFSD

Gulfport Biloxi Regional

Fri 4/17

5:55 pm-11:40 pm

1 stop5h 45m

Sioux Falls Joe Foss Field

Tue 4/21

10:53 am-10:13 pm

2 stops11h 20m

$384

MemphisRapid City

MEM - RAP

MEMRAP

Memphis

Tue 4/28

8:40 am-1:08 pm

1 stop5h 28m

Rapid City

Sat 5/2

7:00 am-2:27 pm

1 stop6h 27m

$389

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/11

Showing 1-10 of 43 resultsSorted by cheapest first
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Best time to book a flight from Mississippi to South Dakota

Have a flexible travel schedule? Discover the best time to fly to South Dakota from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South Dakota
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Dakota

Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated March 16, 2026.
Get a feel of what it's like to fly with American Airlines from Mississippi to South Dakota by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,467 reviews

Crew

7.9

Boarding

7.5

Comfort

7.2

Food

6.4

Overall

7.1

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,467 reviews
American Airlines
7.1
Good
11,467 reviews

Crew

7.9

Boarding

7.5

Comfort

7.2

Food

6.4

Overall

7.1

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to South Dakota?

    Departing from Mississippi to South Dakota will take you 5h 45m. Airlines will cover a distance of 1002 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Mississippi to South Dakota that include hotel bookings?

    Yes. In addition to deals on Mississippi to South Dakota flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South Dakota?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South Dakota.

  • Can I find deals for business class flights from Mississippi to South Dakota?

    Yes. Cheapflights offers flight deals from Mississippi to South Dakota by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Mississippi to South Dakota

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Top airline flying from Mississippi to South Dakota

Discover the top airline that operate flights from Mississippi to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$594FlexibilityNo cancel feeOn-time71%

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