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South Dakota

$261+ Cheap flights from Mississippi to South Dakota

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — FSD
Dec 4 — Dec 111
Thu 12/4
Thu 12/11
1 adult, Economy
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Cheap flight deals from Mississippi to South Dakota

Keep the following information in mind while searching for Mississippi to South Dakota flight deals. Data was last updated November 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$279
(Delta)

One-way from

$261
(United Airlines)
Provider with most accurate pricing for Jackson-Evers Intl-Sioux Falls Joe Foss Field flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Sioux Falls Joe Foss Field flights.
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From Mississippi to South Dakota
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One-way flight from Mississippi to South Dakota
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Find flight deals from Mississippi to South Dakota

Cheapest flights from Mississippi to South Dakota
Explore the most affordable flight options available from Mississippi to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2025.

This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/185:56 pmMEM - FSD
1 stop5h 13mDelta
Sat 11/225:18 amFSD - MEM
1 stop5h 54mDelta
Deal found 11/3$279
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/128:34 amMEM - RAP
1 stop5h 37mUnited Airlines
Mon 1/1212:35 pmRAP - MEM
1 stop7h 06mUnited Airlines
Deal found 11/2$286
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/108:33 amMEM - FSD
1 stop7h 45mUnited Airlines
Fri 11/218:57 amFSD - MEM
1 stop5h 25mUnited Airlines
Deal found 11/3$309
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1811:52 amMEM - RAP
1 stop4h 53mDelta
Sat 11/224:25 pmRAP - MEM
1 stop5h 08mDelta
Deal found 11/3$309
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/185:20 amGPT - FSD
1 stop7h 01mAmerican Airlines
Sat 11/221:43 pmFSD - GPT
2 stops10h 33mAmerican Airlines
Deal found 11/3$314
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/89:17 pmMEM - FSD
1 stop17h 43mMultiple Airlines
Fri 12/1211:55 amFSD - MEM
1 stop8h 02mMultiple Airlines
Deal found 11/1$315
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1810:29 amMEM - FSD
2 stops10h 41mAmerican Airlines
Sat 11/221:43 pmFSD - MEM
2 stops10h 16mAmerican Airlines
Deal found 11/3$319
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/173:15 pmMEM - RAP
1 stop4h 39mUnited Airlines
Wed 12/243:35 pmRAP - MEM
1 stop5h 54mUnited Airlines
Deal found 11/4$329
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:12 amMEM - FSD
1 stop7h 16mAmerican Airlines
Sun 12/287:29 pmFSD - MEM
1 stop4h 30mAmerican Airlines
Deal found 11/3$338
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/242:50 pmMOB - FSD
1 stop6h 19mAmerican Airlines
Mon 12/85:18 pmFSD - MOB
1 stop5h 44mAmerican Airlines
Deal found 11/4$339
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/181:57 pmJAN - RAP
2 stops9h 02mUnited Airlines
Sat 11/2210:22 amRAP - JAN
2 stops10h 37mUnited Airlines
Deal found 11/3$342
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/243:42 pmMOB - FSD
1 stop7h 27mDelta
Mon 12/81:30 pmFSD - MOB
2 stops9h 29mDelta
Deal found 11/4$344

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Mississippi to South Dakota that are best for you.

Fly from

Mississippi

Fly to

South Dakota

Route

Depart

Return

Price

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Tue 11/18

5:56 pm-11:09 pm

1 stop5h 13m

Sioux Falls Joe Foss Field

Sat 11/22

5:18 am-11:12 am

1 stop5h 54m

$279

MemphisRapid City

MEM - RAP

MEMRAP

Memphis

Fri 12/12

8:34 am-1:11 pm

1 stop5h 37m

Rapid City

Mon 1/12

12:35 pm-8:41 pm

1 stop7h 06m

$286

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Sat 2/21

6:00 am-12:22 pm

1 stop6h 22m

Sioux Falls Joe Foss Field

Tue 2/24

5:00 am-11:43 am

1 stop6h 43m

$293

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Thu 11/20

5:15 am-12:36 pm

1 stop7h 21m

Sioux Falls Joe Foss Field

Tue 11/25

7:16 pm-11:59 pm

1 stop4h 43m

$309

MemphisRapid City

MEM - RAP

MEMRAP

Memphis

Tue 11/18

11:52 am-3:45 pm

1 stop4h 53m

Rapid City

Sat 11/22

4:25 pm-10:33 pm

1 stop5h 08m

$309

GulfportSioux Falls

GPT - FSD

GPTFSD

Gulfport Biloxi Regional

Tue 11/18

5:20 am-12:21 pm

1 stop7h 01m

Sioux Falls Joe Foss Field

Sat 11/22

1:43 pm-12:16 am

2 stops10h 33m

$314

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Mon 12/8

9:17 pm-3:00 pm

1 stop17h 43m

Sioux Falls Joe Foss Field

Fri 12/12

11:55 am-7:57 pm

1 stop8h 02m

$315

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Tue 11/18

10:29 am-9:10 pm

2 stops10h 41m

Sioux Falls Joe Foss Field

Sat 11/22

1:43 pm-11:59 pm

2 stops10h 16m

$319

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Sat 2/21

7:00 am-12:37 pm

1 stop5h 37m

Sioux Falls Joe Foss Field

Tue 2/24

7:00 am-5:15 pm

2 stops10h 15m

$324

MemphisRapid City

MEM - RAP

MEMRAP

Memphis

Wed 12/17

3:15 pm-6:54 pm

1 stop4h 39m

Rapid City

Wed 12/24

3:35 pm-10:29 pm

1 stop5h 54m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 44 results
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Best time to book a flight from Mississippi to South Dakota

Have a flexible travel schedule? Discover the best time to fly to South Dakota from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South Dakota
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Dakota

Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated November 4, 2025.
Get a feel of what it's like to fly with American Airlines from Mississippi to South Dakota by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,040 reviews

Crew

8.0

Overall

7.2

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
11,040 reviews
American Airlines
7.2
Good
11,040 reviews

Crew

8.0

Overall

7.2

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to South Dakota?

    Departing from Mississippi to South Dakota will take you 5h 13m. Airlines will cover a distance of 691 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mississippi to South Dakota one-way?

    The cheapest airlines for a one-way flight from Mississippi to South Dakota are United Airlines ($301), American Airlines ($321), and Delta ($376).

  • Can I find deals for flights from Mississippi to South Dakota that include hotel bookings?

    Yes. In addition to deals on Mississippi to South Dakota flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South Dakota?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South Dakota.

  • Can I find deals for business class flights from Mississippi to South Dakota?

    Yes. Cheapflights offers flight deals from Mississippi to South Dakota by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Mississippi to South Dakota

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Mississippi to South Dakota

Discover the top airline that operate flights from Mississippi to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$699FlexibilityNo cancel feeOn-time71%

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