$383+ Cheap flights from Mississippi to South Dakota
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — FSD
Nov 3 — Nov 101
Round-trip
1 adult, Economy
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Find cheap flights from Mississippi to South Dakota with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mississippi to South Dakota
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Cheapest flights from Mississippi to South DakotaExplore the most affordable flight options available from Mississippi to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 4, 2026.
Explore the most affordable flight options available from Mississippi to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 4, 2026.
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:04 am -
1 stop7h 09m
Mon 10/125:54 pm -
1 stop5h 03m
Deal found 9/30![American Airlines logo]()
$492
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:40 am -
1 stop6h 33m
Tue 10/205:54 pm -
1 stop5h 05m
Deal found 9/29![American Airlines logo]()
$508
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:30 am -
1 stop5h 54m
Sat 12/265:44 am -
1 stop5h 58m
Deal found 10/3![American Airlines logo]()
$528
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:57 pm -
2 stops9h 32m
Fri 10/306:00 am -
2 stops10h 34m
Deal found 9/30![United Airlines logo]()
$577
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:21 pm -
2 stops17h 17m
Mon 11/165:58 pm -
1 stop5h 37m
Deal found 10/1![American Airlines logo]()
$617
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:30 am -
1 stop5h 54m
Mon 12/287:34 pm -
2 stops16h 12m
Deal found 10/3![American Airlines logo]()
$625
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:00 am -
1 stop5h 28m
Thu 11/195:53 pm -
1 stop5h 02m
Deal found 10/3![American Airlines logo]()
$685
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:46 pm -
1 stop6h 10m
Tue 10/2012:51 pm -
1 stop7h 01m
Deal found 10/1![American Airlines logo]()
$685
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:30 am -
1 stop5h 54m
Sun 12/2712:04 pm -
1 stop6h 40m
Deal found 9/30![American Airlines logo]()
$697
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:02 pm -
1 stop4h 45m
Sun 10/41:05 pm -
2 stops10h 16m
Deal found 9/29![Delta logo]()
$704
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:09 pm -
2 stops9h 21m
Tue 10/208:45 am -
2 stops12h 13m
Deal found 10/1![United Airlines logo]()
$713
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:15 pm -
1 stop7h 36m
Fri 10/3012:53 pm -
1 stop6h 09m
Deal found 9/30![American Airlines logo]()
$715
Best flights from Mississippi to South DakotaDiscover carefully curated flight deals from Mississippi to South Dakota that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 4, 2026.
Discover carefully curated flight deals from Mississippi to South Dakota that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 4, 2026.
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/55:19 am -
1 stop8h 18m
Tue 2/91:07 pm -
1 stop7h 49m
Deal found 10/3![American Airlines logo]()
$519
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/51:54 pm -
2 stops9h 56m
Tue 2/96:00 am -
2 stops10h 02m
Deal found 9/29![United Airlines logo]()
$570
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/91:50 pm -
1 stop6h 06m
Mon 11/165:25 am -
1 stop7h 39m
Deal found 10/1![Delta logo]()
$769
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:36 pm -
2 stops10h 05m
Tue 10/205:54 pm -
1 stop5h 05m
Deal found 9/29![American Airlines logo]()
$567
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:57 pm -
2 stops9h 32m
Fri 10/306:00 am -
2 stops10h 34m
Deal found 9/30![United Airlines logo]()
$577
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:21 pm -
2 stops17h 17m
Mon 11/165:58 pm -
1 stop5h 37m
Deal found 10/1![American Airlines logo]()
$617
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/302:00 pm -
2 stops9h 34m
Wed 2/37:00 am -
2 stops8h 33m
Deal found 10/2![United Airlines logo]()
$652
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/301:54 pm -
2 stops9h 14m
Wed 2/37:05 am -
2 stops11h 37m
Deal found 9/29![United Airlines logo]()
$667
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:30 am -
1 stop5h 54m
Mon 12/2812:04 pm -
1 stop6h 40m
Deal found 10/3![American Airlines logo]()
$677
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:00 am -
1 stop5h 28m
Thu 11/195:53 pm -
1 stop5h 02m
Deal found 10/3![American Airlines logo]()
$685
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:09 pm -
2 stops9h 21m
Tue 10/208:45 am -
2 stops12h 13m
Deal found 10/1![United Airlines logo]()
$713
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:46 pm -
1 stop6h 10m
Tue 10/2012:51 pm -
1 stop7h 01m
Deal found 10/1![American Airlines logo]()
$685
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1611:57 am -
2 stops9h 41m
Thu 11/196:00 am -
2 stops10h 34m
Deal found 10/3![United Airlines logo]()
$751
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:30 am -
1 stop5h 54m
Sun 12/2712:04 pm -
1 stop6h 40m
Deal found 10/1![American Airlines logo]()
$697
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:55 pm -
2 stops20h 53m
Mon 11/28:30 am -
2 stops10h 04m
Deal found 10/2![United Airlines logo]()
$765
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:02 pm -
2 stops11h 09m
Sun 10/187:50 am -
2 stops14h 08m
Deal found 9/29![United Airlines logo]()
$942
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:00 am -
1 stop5h 13m
Thu 10/226:20 am -
1 stop5h 25m
Deal found 10/3![American Airlines logo]()
$1,003
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:20 pm -
2 stops26h 55m
Sun 12/273:11 pm -
2 stops29h 04m
Deal found 9/30![United Airlines logo]()
$990
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/91:54 pm -
3 stops9h 50m
Mon 11/1611:22 am -
2 stops8h 12m
Deal found 10/1![United Airlines logo]()
$1,117
Last-minute flights from Mississippi to South DakotaDiscover last-minute flight deals from Mississippi to South Dakota. Data last updated October 4, 2026 and is based on user searches.
Discover last-minute flight deals from Mississippi to South Dakota. Data last updated October 4, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:05 pm -
1 stop6h 42m
Sun 10/41:05 pm -
2 stops10h 16m
Deal found 9/29![Delta logo]()
$704
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:04 am -
1 stop7h 09m
Mon 10/125:54 pm -
1 stop5h 03m
Deal found 9/30![American Airlines logo]()
$492
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:46 pm -
1 stop6h 10m
Tue 10/2012:51 pm -
1 stop7h 01m
Deal found 10/1![American Airlines logo]()
$685
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:09 pm -
2 stops9h 21m
Tue 10/208:45 am -
2 stops12h 13m
Deal found 10/1![United Airlines logo]()
$713
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:40 am -
1 stop6h 33m
Tue 10/205:54 pm -
1 stop5h 05m
Deal found 9/29![American Airlines logo]()
$508
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:55 pm -
2 stops20h 53m
Mon 11/28:30 am -
2 stops10h 04m
Deal found 10/2![United Airlines logo]()
$765
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:57 pm -
2 stops9h 32m
Fri 10/306:00 am -
2 stops10h 34m
Deal found 9/30![United Airlines logo]()
$577
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:15 pm -
1 stop7h 36m
Fri 10/3012:53 pm -
1 stop6h 09m
Deal found 9/30![American Airlines logo]()
$715
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:04 pm -
1 stop6h 51m
Fri 10/308:30 am -
2 stops7h 47m
Deal found 9/30![Delta logo]()
$750
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:21 pm -
2 stops17h 17m
Mon 11/165:58 pm -
1 stop5h 37m
Deal found 10/1![American Airlines logo]()
$617
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:00 am -
1 stop5h 28m
Thu 11/195:53 pm -
1 stop5h 02m
Deal found 10/3![American Airlines logo]()
$685
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1611:57 am -
2 stops9h 41m
Thu 11/196:00 am -
2 stops10h 34m
Deal found 10/3![United Airlines logo]()
$751
One-way flights from Mississippi to South DakotaSearch for one-way flight options from Mississippi to South Dakota. Find affordable one-way fares based on user searches. Data last updated October 4, 2026.
Search for one-way flight options from Mississippi to South Dakota. Find affordable one-way fares based on user searches. Data last updated October 4, 2026.
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:59 pm -
1 stop5h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Delta logo]()
$383
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:40 am -
1 stop6h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![American Airlines logo]()
$403
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:02 pm -
2 stops11h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![United Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:20 pm -
2 stops17h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![United Airlines logo]()
$462
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:20 pm -
2 stops17h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![United Airlines logo]()
$475
Find flight deals from Mississippi to South Dakota
Keep the following information in mind while searching for Mississippi to South Dakota flight deals. Data was last updated October 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $508 (American Airlines) |
One-way from | $383 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 4, 2026.
Use the filters below to find and compare flights from Mississippi to South Dakota that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
JacksonSioux Falls
JAN Jackson-Evers Intl - FSD Sioux Falls Joe Foss Field
JANFSD
Jackson-Evers Intl
Tue 12/22
5:59 pm-11:41 pm
1 stop5h 42m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$383
JacksonSioux Falls
JAN Jackson-Evers Intl - FSD Sioux Falls Joe Foss Field
JANFSD
Jackson-Evers Intl
Wed 12/23
5:30 am-11:24 am
1 stop5h 54m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$403
JacksonSioux Falls
JAN Jackson-Evers Intl - FSD Sioux Falls Joe Foss Field
JANFSD
Jackson-Evers Intl
Tue 12/22
5:20 pm-10:39 am
2 stops17h 19m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$462
GulfportRapid City
GPT Gulfport Biloxi Regional - RAP Rapid City
GPTRAP
Gulfport Biloxi Regional
Fri 2/5
5:19 am-12:37 pm
1 stop8h 18m
Rapid City
Tue 2/9
1:07 pm-9:56 pm
1 stop7h 49m
$519
JacksonSioux Falls
JAN Jackson-Evers Intl - FSD Sioux Falls Joe Foss Field
JANFSD
Jackson-Evers Intl
Sat 10/17
2:36 pm-12:41 am
2 stops10h 05m
Sioux Falls Joe Foss Field
Tue 10/20
5:54 pm-10:59 pm
1 stop5h 05m
$567
GulfportSioux Falls
GPT Gulfport Biloxi Regional - FSD Sioux Falls Joe Foss Field
GPTFSD
Gulfport Biloxi Regional
Fri 2/5
1:54 pm-11:50 pm
2 stops9h 56m
Sioux Falls Joe Foss Field
Tue 2/9
6:00 am-4:02 pm
2 stops10h 02m
$570
JacksonSioux Falls
JAN Jackson-Evers Intl - FSD Sioux Falls Joe Foss Field
JANFSD
Jackson-Evers Intl
Wed 10/28
1:57 pm-11:29 pm
2 stops9h 32m
Sioux Falls Joe Foss Field
Fri 10/30
6:00 am-4:34 pm
2 stops10h 34m
$577
GulfportSioux Falls
GPT Gulfport Biloxi Regional - FSD Sioux Falls Joe Foss Field
GPTFSD
Gulfport Biloxi Regional
Mon 11/9
6:21 pm-11:38 am
2 stops17h 17m
Sioux Falls Joe Foss Field
Mon 11/16
5:58 pm-11:35 pm
1 stop5h 37m
$617
JacksonRapid City
JAN Jackson-Evers Intl - RAP Rapid City
JANRAP
Jackson-Evers Intl
Sat 1/30
2:00 pm-10:34 pm
2 stops9h 34m
Rapid City
Wed 2/3
7:00 am-4:33 pm
2 stops8h 33m
$652
GulfportRapid City
GPT Gulfport Biloxi Regional - RAP Rapid City
GPTRAP
Gulfport Biloxi Regional
Sat 1/30
1:54 pm-10:08 pm
2 stops9h 14m
Rapid City
Wed 2/3
7:05 am-7:42 pm
2 stops11h 37m
$667
Showing 1-10 of 23 resultsSorted by cheapest first
Best time to book a flight from Mississippi to South Dakota
Have a flexible travel schedule? Discover the best time to fly to South Dakota from Mississippi with our price prediction graph.
GPT-FSD
JAN-FSD
JAN-RAP
GPT-RAP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to South Dakota
USMS-USSD
GPT-FSD
JAN-FSD
JAN-RAP
GPT-RAP
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South Dakota
Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated October 4, 2026.
Get a feel of what it's like to fly with American Airlines from Mississippi to South Dakota by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Food
6.4
Comfort
7.2
Entertainment
6.8
Boarding
7.4
Overall
7.0
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Crew
7.9
Food
6.4
Comfort
7.2
Entertainment
6.8
Boarding
7.4
Overall
7.0
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Mississippi to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Mississippi to South Dakota
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Complete your trip
Complete your trip to South Dakota by adding a car rental and/or hotel reservation to your travel itinerary.
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Mississippi and South Dakota flights
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Find a return flight route from South Dakota
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Mississippi to South Dakota flights
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Top airline flying from Mississippi to South Dakota
Discover the top airline that operate flights from Mississippi to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$308 | Average$527 | FlexibilityNo cancel fee | On-time71% |