HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Dakota

$240+ Cheap flights from Mississippi to South Dakota

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/30. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — FSD
jun. 21 — jun. 281
sáb. 6/21
sáb. 6/28
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mississippi to South Dakota with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Mississippi to South Dakota

Keep the following information in mind while searching for Mississippi to South Dakota flight deals. Data was last updated junio 16, 2025.

Round-trip from

$249
(Delta)

One-way from

$240
(American Airlines)
From Mississippi to South Dakota
Search Deals
One-way flight from Mississippi to South Dakota
Search Deals

Find flight deals from Mississippi to South Dakota

Cheapest flights from Mississippi to South Dakota
Explore the most affordable flight options available from Mississippi to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 16, 2025.

This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/96:05 amMEM - FSD
1 stop4h 27mDelta
sáb. 7/126:00 amFSD - MEM
1 stop5h 26mDelta
Deal found 6/14$249
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/83:10 pmMEM - RAP
1 stop6h 29mUnited Airlines
mié. 8/135:30 amRAP - MEM
1 stop7h 37mUnited Airlines
Deal found 6/15$259
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/234:15 pmMOB - FSD
1 stop5h 56mDelta
sáb. 9/275:25 amFSD - MOB
1 stop6h 07mDelta
Deal found 6/14$259
This Mytrip deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/214:04 pmMEM - FSD
1 stop17h 04mAllegiant Air
vie. 7/2511:57 amFSD - MEM
1 stop9h 19mAllegiant Air
Deal found 6/15$266
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/156:25 amMOB - FSD
2 stops14h 38mAmerican Airlines
dom. 8/177:01 amFSD - MOB
1 stop4h 48mAmerican Airlines
Deal found 6/14$279
This Mytrip deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/217:00 amMEM - FSD
2 stops13h 49mMultiple Airlines
vie. 7/2511:57 amFSD - MEM
1 stop9h 19mMultiple Airlines
Deal found 6/15$281
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/2512:30 pmMEM - FSD
2 stops8h 49mAmerican Airlines
dom. 9/285:29 pmFSD - MEM
1 stop5h 09mAmerican Airlines
Deal found 6/14$299
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/75:06 pmMEM - RAP
1 stop5h 00mAmerican Airlines
mié. 7/164:38 pmRAP - MEM
1 stop5h 51mAmerican Airlines
Deal found 6/16$301
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/96:26 amMEM - RAP
1 stop6h 00mDelta
sáb. 8/234:25 pmRAP - MEM
1 stop4h 52mDelta
Deal found 6/14$333
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/145:00 amJAN - RAP
1 stop5h 55mAmerican Airlines
jue. 7/175:36 amRAP - JAN
1 stop5h 15mAmerican Airlines
Deal found 6/15$351
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/114:13 pmBTR - FSD
1 stop5h 48mAmerican Airlines
dom. 7/136:21 amFSD - BTR
1 stop6h 03mAmerican Airlines
Deal found 6/16$399
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/187:30 amMEM - FSD
1 stop7h 05mUnited Airlines
sáb. 6/212:05 pmFSD - MEM
1 stop7h 10mUnited Airlines
Deal found 6/15$409

Cheapflights Fare Finder

Customize your flight search to find flights from Mississippi to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 16, 2025.
Use the filters below to find and compare flights from Mississippi to South Dakota that are best for you.

Fly from

Mississippi

Fly to

South Dakota

Route

Depart

Return

Price

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

mié. 7/9

6:05 am-10:32 am

1 stop4h 27m

Sioux Falls Joe Foss Field

sáb. 7/12

6:00 am-11:26 am

1 stop5h 26m

$249

MemphisRapid City

MEM - RAP

MEMRAP

Memphis

vie. 8/8

3:10 pm-8:39 pm

1 stop6h 29m

Rapid City

mié. 8/13

5:30 am-2:07 pm

1 stop7h 37m

$259

MobileSioux Falls

MOB - FSD

MOBFSD

Mobile

mar. 9/23

4:15 pm-10:11 pm

1 stop5h 56m

Sioux Falls Joe Foss Field

sáb. 9/27

5:25 am-11:32 am

1 stop6h 07m

$259

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

lun. 7/21

4:04 pm-9:08 am

1 stop17h 04m

Sioux Falls Joe Foss Field

vie. 7/25

11:57 am-9:16 pm

1 stop9h 19m

$266

MobileSioux Falls

MOB - FSD

MOBFSD

Mobile

vie. 8/15

6:25 am-9:03 pm

2 stops14h 38m

Sioux Falls Joe Foss Field

dom. 8/17

7:01 am-11:49 am

1 stop4h 48m

$279

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

lun. 7/21

7:00 am-8:49 pm

2 stops13h 49m

Sioux Falls Joe Foss Field

vie. 7/25

11:57 am-9:16 pm

1 stop9h 19m

$281

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

jue. 9/25

12:30 pm-9:19 pm

2 stops8h 49m

Sioux Falls Joe Foss Field

dom. 9/28

5:29 pm-10:38 pm

1 stop5h 09m

$299

MemphisRapid City

MEM - RAP

MEMRAP

Memphis

lun. 7/7

5:06 pm-9:06 pm

1 stop5h 00m

Rapid City

mié. 7/16

4:38 pm-11:29 pm

1 stop5h 51m

$301

MemphisRapid City

MEM - RAP

MEMRAP

Memphis

sáb. 8/9

6:26 am-11:26 am

1 stop6h 00m

Rapid City

sáb. 8/23

4:25 pm-10:17 pm

1 stop4h 52m

$333

JacksonRapid City

JAN - RAP

JANRAP

Jackson-Evers Intl

lun. 7/14

5:00 am-9:55 am

1 stop5h 55m

Rapid City

jue. 7/17

5:36 am-11:51 am

1 stop5h 15m

$351

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/15

Showing 1-10 of 28 results
1
2
3

Best time to book a flight from Mississippi to South Dakota

Have a flexible travel schedule? Discover the best time to fly to South Dakota from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South Dakota

Rainfall in South Dakota by month

Plan your trip to South Dakota by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Dakota ranges from 0.6 - 3.9 inches per month. June is typically the wettest month, when rainfall can reach 3.9 in. January is typically the driest time to visit South Dakota when rainfall is around 0.6 in.

Temperature in South Dakota by month

Plan your trip to South Dakota by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Dakota, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 15.8 F).

Reviews of airlines servicing South Dakota

Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated junio 16, 2025.
Read through reviews of airlines operating flights from Mississippi to South Dakota, such as Delta, United Airlines and Allegiant Air. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,963 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,963 reviews
Delta
8.0
Very good
7,963 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,801 reviews
Delta
8.0
Very good
7,963 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.3
Good
722 reviews
Delta
8.0
Very good
7,963 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,963 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Mississippi to South Dakota one-way?

    The cheapest airlines for a one-way flight from Mississippi to South Dakota are American Airlines ($240), Delta ($271), and United Airlines ($285).

  • Can I find deals for flights from Mississippi to South Dakota that include hotel bookings?

    Yes. In addition to deals on Mississippi to South Dakota flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South Dakota?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South Dakota.

  • Can I find deals for business class flights from Mississippi to South Dakota?

    Yes. Cheapflights offers flight deals from Mississippi to South Dakota by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to South Dakota?

    Currently, September is the cheapest month in which you can book a flight from Mississippi to South Dakota (average of $334). Flying from Mississippi to South Dakota in December is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mississippi to South Dakota

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to LaGuardia flights
Los Angeles to John F Kennedy Intl flights
John F Kennedy Intl to O'Hare Intl flights
Newark to Fort Lauderdale flights
Los Angeles to Seattle flights
John F Kennedy Intl to Los Angeles flights
John F Kennedy Intl to Miami flights
Newark to Miami flights
Los Angeles to Newark flights
Dallas/Fort Worth to Seattle flights
Dallas/Fort Worth to O'Hare Intl flights
John F Kennedy Intl to Seattle flights
John F Kennedy Intl to Las Vegas flights
Newark to O'Hare Intl flights
John F Kennedy Intl to San Francisco flights
LaGuardia to Fort Lauderdale flights
Dallas/Fort Worth to John F Kennedy Intl flights
Newark to Los Angeles flights
Newark to Seattle flights
John F Kennedy Intl to Orlando flights
Los Angeles to Honolulu flights
LaGuardia to O'Hare Intl flights
Dallas/Fort Worth to Newark flights
Newark to Las Vegas flights
Los Angeles to O'Hare Intl flights
O'Hare Intl to John F Kennedy Intl flights
LaGuardia to Miami flights
San Francisco to John F Kennedy Intl flights
Seattle to Los Angeles flights
Dallas/Fort Worth to Las Vegas flights
Atlanta to John F Kennedy Intl flights
Newark to Orlando flights
LaGuardia to Dallas/Fort Worth flights
San Francisco to Newark flights
John F Kennedy Intl to Atlanta flights
John F Kennedy Intl to Fort Lauderdale flights
O'Hare Intl to Dallas/Fort Worth flights
Newark to Dallas/Fort Worth flights
Atlanta to Newark flights
Newark to San Francisco flights
Dallas/Fort Worth to Los Angeles flights
LaGuardia to Orlando flights
Los Angeles to LaGuardia flights
O'Hare Intl to Seattle flights
Los Angeles to San Francisco flights
Miami to John F Kennedy Intl flights
Los Angeles to Miami flights
San Francisco to Los Angeles flights
Los Angeles to Dallas/Fort Worth flights
Boston to O'Hare Intl flights

Top airline flying from Mississippi to South Dakota

Discover the top airline that operate flights from Mississippi to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$273Average$552FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.