$221+ Cheap flights from Mississippi to South Dakota
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/9. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — FSD
May 7 — May 141
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Mississippi to South Dakota with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mississippi to South Dakota
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mississippi to South DakotaExplore the most affordable flight options available from Mississippi to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 7, 2026.
Explore the most affordable flight options available from Mississippi to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 7, 2026.
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:40 am
MEM
- RAP
1 stop5h 43m
American Airlines
Tue 5/511:53 am
RAP
- MEM
1 stop6h 11m
American Airlines
Deal found 4/5![American Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:00 am
MEM
- RAP
1 stop6h 55m
American Airlines
Tue 8/256:10 pm
RAP
- MEM
1 stop4h 43m
American Airlines
Deal found 4/3![American Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:45 pm
MEM
- FSD
1 stop22h 36m
Multiple Airlines
Mon 4/276:11 pm
FSD
- MEM
2 stops21h 29m
Multiple Airlines
Deal found 4/4![Multiple Airlines logo]()
$326
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:40 am
MEM
- FSD
1 stop5h 19m
American Airlines
Mon 4/275:28 pm
FSD
- MEM
1 stop5h 30m
American Airlines
Deal found 4/4![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:40 am
MEM
- FSD
1 stop7h 16m
American Airlines
Mon 5/41:41 pm
FSD
- MEM
1 stop7h 44m
American Airlines
Deal found 4/4![American Airlines logo]()
$337
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:00 am
MEM
- FSD
2 stops9h 47m
American Airlines
Sat 5/161:34 pm
FSD
- MEM
2 stops10h 13m
American Airlines
Deal found 4/7![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:22 am
MOB
- FSD
1 stop7h 34m
American Airlines
Sat 5/25:28 pm
FSD
- MOB
1 stop5h 31m
American Airlines
Deal found 4/4![American Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:45 pm
MEM
- FSD
1 stop22h 36m
Multiple Airlines
Mon 5/46:11 pm
FSD
- MEM
2 stops22h 21m
Multiple Airlines
Deal found 4/4![Multiple Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:40 am
MEM
- RAP
1 stop5h 43m
American Airlines
Sun 4/264:57 pm
RAP
- MEM
1 stop5h 01m
American Airlines
Deal found 4/7![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/55:38 am
MEM
- FSD
1 stop7h 03m
American Airlines
Thu 4/307:39 pm
FSD
- MEM
1 stop4h 20m
American Airlines
Deal found 4/4![American Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2712:01 pm
MEM
- RAP
1 stop5h 29m
American Airlines
Sat 7/44:55 pm
RAP
- MEM
1 stop6h 09m
American Airlines
Deal found 4/3![American Airlines logo]()
$393
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/510:59 am
MEM
- FSD
2 stops8h 11m
American Airlines
Wed 5/275:35 pm
FSD
- MEM
1 stop4h 50m
American Airlines
Deal found 4/4![American Airlines logo]()
$394
Best flights from Mississippi to South DakotaDiscover carefully curated flight deals from Mississippi to South Dakota that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 7, 2026.
Discover carefully curated flight deals from Mississippi to South Dakota that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 7, 2026.
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:40 am
MEM
- RAP
1 stop5h 43m
American Airlines
Tue 5/511:53 am
RAP
- MEM
2 stops10h 49m
American Airlines
Deal found 4/5![American Airlines logo]()
$323
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/113:24 pm
MEM
- RAP
2 stops7h 59m
United Airlines
Tue 8/2511:08 am
RAP
- MEM
2 stops7h 42m
United Airlines
Deal found 4/3![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:20 pm
BTR
- FSD
1 stop6h 49m
Delta
Sun 9/205:15 am
FSD
- BTR
2 stops9h 32m
Delta
Deal found 4/5![Delta logo]()
$547
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:58 pm
MEM
- FSD
1 stop6h 11m
American Airlines
Sat 5/161:34 pm
FSD
- MEM
1 stop5h 24m
American Airlines
Deal found 4/7![American Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:40 am
MEM
- FSD
1 stop7h 16m
American Airlines
Tue 5/56:00 am
FSD
- MEM
1 stop5h 46m
American Airlines
Deal found 4/4![American Airlines logo]()
$337
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:22 am
MOB
- FSD
1 stop7h 34m
American Airlines
Sat 5/25:28 pm
FSD
- MOB
1 stop5h 31m
American Airlines
Deal found 4/4![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:30 am
MEM
- RAP
2 stops10h 30m
United Airlines
Wed 4/298:30 am
RAP
- MEM
1 stop4h 54m
United Airlines
Deal found 4/3![United Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:00 am
MEM
- FSD
2 stops9h 47m
American Airlines
Mon 4/271:41 pm
FSD
- MEM
2 stops10h 06m
American Airlines
Deal found 4/4![American Airlines logo]()
$344
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/259:46 am
MEM
- RAP
2 stops11h 46m
United Airlines
Sat 8/291:33 pm
RAP
- MEM
1 stop7h 24m
United Airlines
Deal found 4/5![United Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:40 am
MEM
- RAP
1 stop5h 43m
American Airlines
Sun 4/2611:53 am
RAP
- MEM
2 stops10h 54m
American Airlines
Deal found 4/7![American Airlines logo]()
$354
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/251:58 pm
JAN
- RAP
2 stops9h 30m
United Airlines
Tue 4/281:00 pm
RAP
- JAN
2 stops7h 59m
United Airlines
Deal found 4/5![United Airlines logo]()
$454
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
MEM
- FSD
1 stop4h 12m
Delta
Tue 5/54:17 pm
FSD
- MEM
2 stops7h 09m
Delta
Deal found 4/4![Delta logo]()
$586
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:00 pm
BTR
- FSD
2 stops9h 44m
United Airlines
Sun 4/266:00 am
FSD
- BTR
2 stops9h 33m
United Airlines
Deal found 4/7![United Airlines logo]()
$479
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2712:01 pm
MEM
- RAP
1 stop5h 29m
American Airlines
Sat 7/412:41 pm
RAP
- MEM
2 stops10h 03m
American Airlines
Deal found 4/3![American Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:00 am
GPT
- FSD
1 stop7h 56m
American Airlines
Thu 5/285:35 pm
FSD
- GPT
1 stop5h 26m
American Airlines
Deal found 4/5![American Airlines logo]()
$402
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:09 pm
BTR
- RAP
2 stops7h 24m
United Airlines
Tue 7/1411:20 am
RAP
- BTR
2 stops10h 26m
United Airlines
Deal found 4/4![United Airlines logo]()
$538
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:31 am
MEM
- FSD
1 stop5h 25m
American Airlines
Sat 4/181:41 pm
FSD
- MEM
1 stop5h 17m
American Airlines
Deal found 4/7![American Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:23 pm
BTR
- FSD
1 stop7h 32m
American Airlines
Mon 9/215:54 pm
FSD
- BTR
1 stop5h 02m
American Airlines
Deal found 4/3![American Airlines logo]()
$441
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:14 pm
BTR
- FSD
2 stops18h 12m
United Airlines
Mon 9/219:36 am
FSD
- BTR
2 stops27h 39m
United Airlines
Deal found 4/5![United Airlines logo]()
$638
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/94:53 pm
BTR
- RAP
1 stop6h 05m
American Airlines
Wed 5/134:57 pm
RAP
- BTR
1 stop4h 54m
American Airlines
Deal found 4/6![American Airlines logo]()
$481
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1611:48 am
MOB
- FSD
1 stop5h 06m
American Airlines
Wed 7/225:34 pm
FSD
- MOB
1 stop6h 14m
American Airlines
Deal found 4/3![American Airlines logo]()
$484
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:09 pm
BTR
- RAP
2 stops17h 15m
United Airlines
Sat 7/113:43 pm
RAP
- BTR
1 stop18h 37m
United Airlines
Deal found 4/5![United Airlines logo]()
$732
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:00 am
MOB
- FSD
2 stops13h 07m
United Airlines
Wed 7/225:05 pm
FSD
- MOB
2 stops25h 09m
United Airlines
Deal found 4/7![United Airlines logo]()
$763
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:18 am
MOB
- ABR
2 stops7h 54m
Delta
Fri 5/152:50 pm
ABR
- MOB
2 stops8h 38m
Delta
Deal found 4/6![Delta logo]()
$1,359
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:31 am
MEM
- FSD
1 stop5h 25m
American Airlines
Tue 5/57:39 pm
FSD
- MEM
1 stop4h 20m
American Airlines
Deal found 4/4![American Airlines logo]()
$570
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2211:00 am
MOB
- FSD
2 stops11h 07m
United Airlines
Wed 7/295:05 pm
FSD
- MOB
2 stops18h 52m
United Airlines
Deal found 4/4![United Airlines logo]()
$788
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/68:10 am
BTR
- RAP
1 stop5h 01m
American Airlines
Sat 7/114:55 pm
RAP
- BTR
1 stop5h 02m
American Airlines
Deal found 4/4![American Airlines logo]()
$579
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am
BTR
- RAP
1 stop4h 49m
American Airlines
Mon 9/284:58 pm
RAP
- BTR
1 stop4h 58m
American Airlines
Deal found 4/3![American Airlines logo]()
$593
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:00 pm
GPT
- FSD
3 stops9h 43m
United Airlines
Thu 5/286:00 am
FSD
- GPT
2 stops10h 11m
United Airlines
Deal found 4/5![United Airlines logo]()
$921
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:18 am
MOB
- ABR
2 stops7h 54m
Delta
Fri 5/156:30 am
ABR
- MOB
2 stops9h 18m
Delta
Deal found 4/5![Delta logo]()
$1,859
Last-minute flights from Mississippi to South DakotaDiscover last-minute flight deals from Mississippi to South Dakota. Data last updated April 7, 2026 and is based on user searches.
Discover last-minute flight deals from Mississippi to South Dakota. Data last updated April 7, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:31 am
MEM
- RAP
1 stop6h 07m
American Airlines
Wed 4/221:08 pm
RAP
- MEM
1 stop4h 50m
American Airlines
Deal found 4/7![American Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:31 am
MEM
- FSD
1 stop5h 25m
American Airlines
Sat 4/181:41 pm
FSD
- MEM
1 stop5h 17m
American Airlines
Deal found 4/7![American Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:40 am
MEM
- RAP
1 stop5h 43m
American Airlines
Sun 4/264:57 pm
RAP
- MEM
1 stop5h 01m
American Airlines
Deal found 4/7![American Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:45 pm
MEM
- FSD
1 stop22h 36m
Multiple Airlines
Mon 4/276:11 pm
FSD
- MEM
2 stops21h 29m
Multiple Airlines
Deal found 4/4![Multiple Airlines logo]()
$326
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:40 am
MEM
- FSD
1 stop5h 19m
American Airlines
Mon 4/275:28 pm
FSD
- MEM
1 stop5h 30m
American Airlines
Deal found 4/4![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/253:58 pm
MEM
- RAP
1 stop7h 30m
United Airlines
Wed 4/291:00 pm
RAP
- MEM
1 stop6h 48m
United Airlines
Deal found 4/3![United Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:40 am
MEM
- RAP
1 stop5h 43m
American Airlines
Tue 5/511:53 am
RAP
- MEM
1 stop6h 11m
American Airlines
Deal found 4/5![American Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:22 am
MOB
- FSD
1 stop7h 34m
American Airlines
Sat 5/25:28 pm
FSD
- MOB
1 stop5h 31m
American Airlines
Deal found 4/4![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:40 am
MEM
- FSD
1 stop7h 16m
American Airlines
Mon 5/41:41 pm
FSD
- MEM
1 stop7h 44m
American Airlines
Deal found 4/4![American Airlines logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:45 pm
MEM
- FSD
1 stop22h 36m
Multiple Airlines
Mon 5/46:11 pm
FSD
- MEM
2 stops22h 21m
Multiple Airlines
Deal found 4/4![Multiple Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:00 am
MEM
- FSD
2 stops9h 47m
American Airlines
Sat 5/161:34 pm
FSD
- MEM
2 stops10h 13m
American Airlines
Deal found 4/7![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:00 am
GPT
- FSD
1 stop7h 56m
American Airlines
Thu 5/285:35 pm
FSD
- GPT
1 stop5h 26m
American Airlines
Deal found 4/5![American Airlines logo]()
$402
One-way flights from Mississippi to South DakotaSearch for one-way flight options from Mississippi to South Dakota. Find affordable one-way fares based on user searches. Data last updated April 7, 2026.
Search for one-way flight options from Mississippi to South Dakota. Find affordable one-way fares based on user searches. Data last updated April 7, 2026.
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:32 am
MEM
- RAP
1 stop8h 03m
Delta
Deal found 4/3![Delta logo]()
$221
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:31 am
MEM
- FSD
1 stop5h 25m
American Airlines
Deal found 4/7![American Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:46 pm
MOB
- FSD
1 stop7h 03m
Delta
Deal found 4/6![Delta logo]()
$311
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:49 am
MOB
- FSD
2 stops8h 26m
American Airlines
Deal found 4/3![American Airlines logo]()
$316
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/139:00 am
MOB
- FSD
2 stops11h 20m
United Airlines
Deal found 4/5![United Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/191:30 pm
BTR
- FSD
1 stop6h 29m
Delta
Deal found 4/6![Delta logo]()
$381
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/184:53 pm
BTR
- RAP
1 stop6h 05m
American Airlines
Deal found 4/6![American Airlines logo]()
$386
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/34:00 pm
BTR
- FSD
1 stop7h 40m
Delta
Deal found 4/5![Delta logo]()
$390
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:03 am
BTR
- RAP
2 stops10h 45m
Delta
Deal found 4/6![Delta logo]()
$396
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:15 pm
BTR
- RAP
2 stops26h 00m
United Airlines
Deal found 4/4![United Airlines logo]()
$418
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:09 pm
BTR
- FSD
2 stops27h 58m
United Airlines
Deal found 4/6![United Airlines logo]()
$469
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/312:01 pm
BTR
- FSD
2 stops11h 10m
American Airlines
Deal found 4/5![American Airlines logo]()
$487
Find flight deals from Mississippi to South Dakota
Keep the following information in mind while searching for Mississippi to South Dakota flight deals. Data was last updated April 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $318 (American Airlines) |
One-way from | $221 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
Use the filters below to find and compare flights from Mississippi to South Dakota that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MemphisRapid City
MEM - RAP
MEMRAP
Memphis
Tue 4/28
6:40 am-11:23 am
1 stop5h 43m
Rapid City
Tue 5/5
11:53 am-11:42 pm
2 stops10h 49m
$323
MemphisSioux Falls
MEM - FSD
MEMFSD
Memphis
Sat 5/2
12:58 pm-7:09 pm
1 stop6h 11m
Sioux Falls Joe Foss Field
Sat 5/16
1:34 pm-6:58 pm
1 stop5h 24m
$329
MemphisSioux Falls
MEM - FSD
MEMFSD
Memphis
Thu 4/30
5:40 am-12:56 pm
1 stop7h 16m
Sioux Falls Joe Foss Field
Tue 5/5
6:00 am-11:46 am
1 stop5h 46m
$337
MobileSioux Falls
MOB - FSD
MOBFSD
Mobile
Tue 4/28
5:22 am-12:56 pm
1 stop7h 34m
Sioux Falls Joe Foss Field
Sat 5/2
5:28 pm-10:59 pm
1 stop5h 31m
$339
MemphisSioux Falls
MEM - FSD
MEMFSD
Memphis
Thu 4/23
5:00 am-2:47 pm
2 stops9h 47m
Sioux Falls Joe Foss Field
Mon 4/27
1:41 pm-11:47 pm
2 stops10h 06m
$344
MemphisRapid City
MEM - RAP
MEMRAP
Memphis
Tue 8/11
3:24 pm-10:23 pm
2 stops7h 59m
Rapid City
Tue 8/25
11:08 am-7:50 pm
2 stops7h 42m
$349
MemphisRapid City
MEM - RAP
MEMRAP
Memphis
Wed 4/22
6:40 am-11:23 am
1 stop5h 43m
Rapid City
Sun 4/26
11:53 am-11:47 pm
2 stops10h 54m
$354
MemphisRapid City
MEM - RAP
MEMRAP
Memphis
Sat 6/27
12:01 pm-4:30 pm
1 stop5h 29m
Rapid City
Sat 7/4
12:41 pm-11:44 pm
2 stops10h 03m
$398
GulfportSioux Falls
GPT - FSD
GPTFSD
Gulfport Biloxi Regional
Wed 5/20
5:00 am-12:56 pm
1 stop7h 56m
Sioux Falls Joe Foss Field
Thu 5/28
5:35 pm-11:01 pm
1 stop5h 26m
$402
MemphisSioux Falls
MEM - FSD
MEMFSD
Memphis
Fri 4/17
7:31 am-12:56 pm
1 stop5h 25m
Sioux Falls Joe Foss Field
Sat 4/18
1:41 pm-6:58 pm
1 stop5h 17m
$419
Showing 1-10 of 40 resultsSorted by cheapest first
Best time to book a flight from Mississippi to South Dakota
Have a flexible travel schedule? Discover the best time to fly to South Dakota from Mississippi with our price prediction graph.
MEM-RAP
MEM-FSD
MOB-FSD
GPT-FSD
BTR-FSD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to South Dakota
USMS-USSD
MEM-RAP
MEM-FSD
MOB-FSD
GPT-FSD
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South Dakota
Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated April 7, 2026.
Get a feel of what it's like to fly with American Airlines from Mississippi to South Dakota by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.9
Crew
7.9
Comfort
7.2
Food
6.4
Boarding
7.5
Overall
7.1
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Entertainment
6.9
Crew
7.9
Comfort
7.2
Food
6.4
Boarding
7.5
Overall
7.1
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Related info for your journey
Find useful and relevant information for your journey from Mississippi to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for Mississippi to South Dakota
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Dakota by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mississippi to South Dakota by cabin class
Find flights from Mississippi to South Dakota, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mississippi and South Dakota flights
Browse other Mississippi and South Dakota flight options. Last updated on April 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Dakota
Find the right flight back to Mississippi after your stay in South Dakota
Mississippi to South Dakota flights
Consider these flights traveling from Mississippi to South Dakota.
Top airline flying from Mississippi to South Dakota
Discover the top airline that operate flights from Mississippi to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$594 | FlexibilityNo cancel fee | On-time71% |