
Keep the following information in mind while searching for San Luis Obispo to South Carolina flight deals. Data was last updated November 11, 2026.
Round-trip from | $419 (United Airlines) |
|---|---|
One-way from | $404 (United Airlines) |
Fly from
Fly to
Route
Depart
Return
San Luis ObispoCharleston
SBP San Luis Obispo County - CHS Charleston
SBPCHS
San Luis Obispo County
Sat 2/27
5:00 am-2:56 pm
1 stop6h 56m
Charleston
Tue 3/2
4:04 pm-9:20 pm
1 stop8h 16m
San Luis ObispoGreenville
SBP San Luis Obispo County - GSP Greenville
SBPGSP
San Luis Obispo County
Thu 12/17
12:39 pm-10:33 pm
1 stop6h 54m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
San Luis ObispoGreenville
SBP San Luis Obispo County - GSP Greenville
SBPGSP
San Luis Obispo County
Mon 12/14
7:06 pm-11:06 am
2 stops13h 00m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
San Luis ObispoGreenville
SBP San Luis Obispo County - GSP Greenville
SBPGSP
San Luis Obispo County
Thu 12/17
5:07 pm-9:22 am
2 stops13h 15m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
San Luis ObispoCharleston
SBP San Luis Obispo County - CHS Charleston
SBPCHS
San Luis Obispo County
Sun 2/28
7:01 pm-10:01 am
2 stops12h 00m
Charleston
Sun 3/7
6:48 am-11:53 am
1 stop8h 05m
San Luis ObispoMyrtle Beach
SBP San Luis Obispo County - MYR Myrtle Beach Intl
SBPMYR
San Luis Obispo County
Mon 5/10
4:32 pm-8:27 am
2 stops12h 55m
Myrtle Beach Intl
Sat 5/15
9:37 am-6:32 pm
2 stops11h 55m
San Luis ObispoGreenville
SBP San Luis Obispo County - GSP Greenville
SBPGSP
San Luis Obispo County
Sat 1/23
6:10 am-9:03 pm
2 stops11h 53m
Greenville
Tue 1/26
10:40 am-5:27 pm
2 stops9h 47m
San Luis ObispoGreenville
SBP San Luis Obispo County - GSP Greenville
SBPGSP
San Luis Obispo County
Sat 2/6
6:10 am-9:03 pm
2 stops11h 53m
Greenville
Tue 2/9
6:30 am-5:27 pm
2 stops13h 57m
San Luis ObispoGreenville
SBP San Luis Obispo County - GSP Greenville
SBPGSP
San Luis Obispo County
Wed 12/16
8:00 am-9:59 pm
3 stops10h 59m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
San Luis ObispoCharleston
SBP San Luis Obispo County - CHS Charleston
SBPCHS
San Luis Obispo County
Sun 2/28
4:40 pm-10:05 am
2 stops14h 25m
Charleston
Sun 3/7
9:08 am-7:55 pm
2 stops13h 47m
Everything you need to know about your flight from San Luis Obispo to South Carolina
Food
Overall
Comfort
Entertainment
Boarding
Crew
Reviews
Dynasty,May 2026
LAX - EWR
Food
Overall
Comfort
Entertainment
Boarding
Crew
Reviews
Dynasty,May 2026
LAX - EWR
Food
Overall
Comfort
Entertainment
Boarding
Crew
Reviews
Dynasty,May 2026
LAX - EWR
Find useful and relevant information for your journey from San Luis Obispo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$319 | Average$780 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$359 | Average$558 | FlexibilityNo cancel fee | On-time69% |