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South Carolina

$125+ Cheap flights from Panama City, FL (ECP) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/9. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — CHS
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Panama City to South Carolina

Keep the following information in mind while searching for Panama City to South Carolina flight deals. Data was last updated junio 12, 2025.

Round-trip from

$249
(American Airlines)

One-way from

$125
(American Airlines)

Popular in

March

Cheapest in

August

Average price

$406
From Panama City NW Florida Beaches to South Carolina
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One-way flight from Panama City NW Florida Beaches to South Carolina
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Highest demand for flights based on searches. 20% potential increase in price ($92 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($34 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Panama City to South Carolina

Cheapest flights from Panama City to South Carolina
Explore the most affordable flight options available from Panama City to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/812:25 pmECP - MYR
1 stop4h 01mAmerican Airlines
sáb. 7/127:57 pmMYR - ECP
1 stop4h 56mAmerican Airlines
Deal found 6/11$249
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/304:52 pmECP - CHS
1 stop6h 07mDelta
mar. 8/59:30 amCHS - ECP
1 stop5h 27mDelta
Deal found 6/11$273
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/239:18 amECP - GSP
1 stop3h 57mDelta
lun. 7/285:30 amGSP - ECP
1 stop4h 03mDelta
Deal found 6/10$278
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/125:30 amECP - CHS
1 stop3h 52mAmerican Airlines
lun. 7/146:00 amCHS - ECP
1 stop5h 08mAmerican Airlines
Deal found 6/12$278
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/56:06 pmECP - GSP
1 stop3h 52mAmerican Airlines
dom. 9/76:00 amGSP - ECP
1 stop4h 42mAmerican Airlines
Deal found 6/11$299
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/141:04 pmECP - MYR
1 stop5h 01mDelta
lun. 7/217:50 pmMYR - ECP
1 stop4h 31mDelta
Deal found 6/11$307
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/510:40 amECP - GSP
1 stop6h 25mSouthwest
dom. 9/77:15 amGSP - ECP
2 stops11h 25mSouthwest
Deal found 6/11$330
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/146:15 amECP - MYR
2 stops10h 00mSouthwest
lun. 7/217:10 pmMYR - ECP
1 stop4h 05mSouthwest
Deal found 6/11$352
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/309:30 amECP - CHS
2 stops7h 35mSouthwest
mar. 8/57:10 amCHS - ECP
1 stop6h 20mSouthwest
Deal found 6/11$399
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/126:30 amECP - CHS
1 stop15h 15mUnited Airlines
lun. 7/147:40 pmCHS - ECP
2 stops18h 43mUnited Airlines
Deal found 6/10$642
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/232:05 pmECP - GSP
2 stops23h 12mUnited Airlines
lun. 7/285:34 pmGSP - ECP
1 stop21h 43mUnited Airlines
Deal found 6/10$647
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/108:40 amECP - MYR
2 stops28h 55mUnited Airlines
jue. 7/174:50 pmMYR - ECP
2 stops30h 10mUnited Airlines
Deal found 6/11$698

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Panama City to South Carolina that are best for you.

Fly from

Panama City

Fly to

South Carolina

Route

Depart

Return

Price

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

mar. 7/8

12:25 pm-5:26 pm

1 stop4h 01m

Myrtle Beach Intl

sáb. 7/12

7:57 pm-11:53 pm

1 stop4h 56m

$249

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

mié. 7/30

4:52 pm-11:59 pm

1 stop6h 07m

Charleston

mar. 8/5

9:30 am-1:57 pm

1 stop5h 27m

$273

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

mié. 7/23

9:18 am-2:15 pm

1 stop3h 57m

Greenville

lun. 7/28

5:30 am-8:33 am

1 stop4h 03m

$278

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

sáb. 7/12

5:30 am-10:22 am

1 stop3h 52m

Charleston

lun. 7/14

6:00 am-10:08 am

1 stop5h 08m

$278

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

vie. 9/5

6:06 pm-10:58 pm

1 stop3h 52m

Greenville

dom. 9/7

6:00 am-9:42 am

1 stop4h 42m

$299

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

lun. 7/14

1:04 pm-7:05 pm

1 stop5h 01m

Myrtle Beach Intl

lun. 7/21

7:50 pm-11:21 pm

1 stop4h 31m

$307

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

vie. 9/5

10:40 am-6:05 pm

1 stop6h 25m

Greenville

dom. 9/7

7:15 am-5:40 pm

2 stops11h 25m

$330

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

lun. 7/14

6:15 am-5:15 pm

2 stops10h 00m

Myrtle Beach Intl

lun. 7/21

7:10 pm-10:15 pm

1 stop4h 05m

$352

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

mié. 7/30

9:30 am-6:05 pm

2 stops7h 35m

Charleston

mar. 8/5

7:10 am-12:30 pm

1 stop6h 20m

$399

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

sáb. 7/12

6:30 am-10:45 pm

1 stop15h 15m

Charleston

lun. 7/14

7:40 pm-1:23 pm

2 stops18h 43m

$642

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 20 results
1
2

Best time to book a flight from Panama City to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to South Carolina

What is the cheapest month to book a flight from Panama City, Florida to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to South Carolina (average of $217). Flying from Panama City, Florida to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to SC?

Find hourly flight availability from Panama City to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated junio 12, 2025.
Get a feel of what it's like to fly with Southwest, Delta and United Airlines from Panama City to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,287 reviews

Crew

8.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Food

7.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Crew

8.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Food

7.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,946 reviews
Southwest
8.0
Very good
4,287 reviews

Crew

8.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Food

7.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,790 reviews
Southwest
8.0
Very good
4,287 reviews

Crew

8.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Food

7.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,287 reviews

Crew

8.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Food

7.1

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Panama City to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to South Carolina?

    For a flight from Panama City to South Carolina, you will be flying from NW Florida Beaches. Panama City NW Florida Beaches (ECP) is just 16.0 mi from the center of the city.

  • What are the cheapest airlines to fly from Panama City, Florida to South Carolina one-way?

    The cheapest airlines for a one-way flight from Panama City, Florida to South Carolina are American Airlines ($125), Delta ($125), and Southwest ($169).

  • What are the most popular routes from Panama City, Florida to South Carolina?

    Most travelers choose Panama City NW Florida Beaches - Charleston, Panama City NW Florida Beaches - Greenville or Panama City NW Florida Beaches - Myrtle Beach Intl when deciding on the best route from Panama City, Florida to South Carolina.

  • Can I find deals for flights from Panama City to South Carolina that include hotel bookings?

    Yes. In addition to deals on Panama City to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to South Carolina.

  • Can I find deals for business class flights from Panama City to South Carolina?

    Yes. Cheapflights offers flight deals from Panama City to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to South Carolina (average of $217). Flying from Panama City, Florida to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama City to South Carolina

Discover the top 2 airlines that operate flights from Panama City to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$206Average$456FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$225Average$411FlexibilityNo cancel feeOn-time71%

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