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South Carolina

$194+ Cheap flights from Panama City, FL (ECP) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — CHS
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
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Cheap flight deals from Panama City to South Carolina

Keep the following information in mind while searching for Panama City to South Carolina flight deals. Data was last updated April 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$246
(Delta)

One-way from

$194
(American Airlines)

Popular in

March

Cheapest in

August

Average price

$357
Provider with most accurate pricing for Panama City NW Florida Beaches-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Myrtle Beach Intl flights.
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From Panama City NW Florida Beaches to South Carolina
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One-way flight from Panama City NW Florida Beaches to South Carolina
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Highest demand for flights based on searches. 23% potential increase in price ($104 potential increase over avg. RT price).
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Cheapest flight prices on average. 11% potential price decrease ($36 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Panama City to South Carolina

Cheapest flights from Panama City to South Carolina
Explore the most affordable flight options available from Panama City to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/306:00 amECP - GSP
1 stop3h 36mDelta
Thu 6/55:25 amGSP - ECP
1 stop3h 51mDelta
Deal found 4/29$246
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/217:02 pmECP - CHS
1 stop3h 46mAmerican Airlines
Wed 6/256:27 amCHS - ECP
1 stop6h 36mAmerican Airlines
Deal found 4/28$302
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/125:05 pmECP - CHS
1 stop5h 54mDelta
Mon 7/146:23 pmCHS - ECP
1 stop5h 58mDelta
Deal found 4/28$307
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/146:00 amECP - MYR
1 stop3h 08mDelta
Wed 5/216:00 amMYR - ECP
1 stop3h 16mDelta
Deal found 4/28$308
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/217:15 amECP - CHS
2 stops10h 05mSouthwest
Thu 5/225:50 amCHS - ECP
1 stop3h 55mSouthwest
Deal found 4/28$332
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/217:15 amECP - MYR
2 stops11h 50mSouthwest
Sat 5/2412:15 pmMYR - ECP
2 stops9h 00mSouthwest
Deal found 4/28$369
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/309:20 amECP - GSP
1 stop8h 15mSouthwest
Thu 6/55:45 amGSP - ECP
2 stops10h 20mSouthwest
Deal found 4/29$413
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1412:25 pmECP - MYR
1 stop5h 47mAmerican Airlines
Wed 5/215:00 amMYR - ECP
2 stops10h 50mAmerican Airlines
Deal found 4/28$565
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/172:03 pmECP - MYR
1 stop23h 32mUnited Airlines
Sat 6/2111:18 amMYR - ECP
1 stop26h 47mUnited Airlines
Deal found 4/28$710
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/65:07 pmECP - CHS
2 stops21h 03mUnited Airlines
Mon 6/97:41 pmCHS - ECP
3 stops18h 25mUnited Airlines
Deal found 4/28$717

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Panama City to South Carolina that are best for you.

Fly from

Panama City

Fly to

South Carolina

Route

Depart

Return

Price

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Fri 5/30

6:00 am-10:36 am

1 stop3h 36m

Greenville

Thu 6/5

5:25 am-8:16 am

1 stop3h 51m

$246

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Sat 6/21

7:02 pm-11:48 pm

1 stop3h 46m

Charleston

Wed 6/25

6:27 am-12:03 pm

1 stop6h 36m

$302

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Sat 7/12

5:05 pm-11:59 pm

1 stop5h 54m

Charleston

Mon 7/14

6:23 pm-11:21 pm

1 stop5h 58m

$307

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Wed 5/14

7:20 am-12:29 pm

1 stop4h 09m

Myrtle Beach Intl

Wed 5/21

6:00 am-8:16 am

1 stop3h 16m

$308

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Wed 5/21

7:15 am-6:20 pm

2 stops10h 05m

Charleston

Thu 5/22

5:50 am-8:45 am

1 stop3h 55m

$332

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Fri 5/30

9:20 am-6:35 pm

1 stop8h 15m

Greenville

Thu 6/5

5:45 am-3:05 pm

2 stops10h 20m

$413

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Wed 5/14

10:22 am-5:39 pm

1 stop6h 17m

Myrtle Beach Intl

Wed 5/21

5:00 am-2:50 pm

2 stops10h 50m

$558

Panama CityMyrtle Beach

ECP - MYR

ECPMYR

Panama City NW Florida Beaches

Tue 6/17

2:03 pm-2:35 pm

1 stop23h 32m

Myrtle Beach Intl

Sat 6/21

11:18 am-1:05 pm

1 stop26h 47m

$710

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Fri 6/6

5:07 pm-3:10 pm

2 stops21h 03m

Charleston

Mon 6/9

7:41 pm-1:06 pm

3 stops18h 25m

$717

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Mon 5/12

10:22 am-3:30 pm

1 stop4h 08m

$194

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Best time to book a flight from Panama City to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to South Carolina

What is the cheapest month to book a flight from Panama City, Florida to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to South Carolina (average of $217). Flying from Panama City, Florida to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to SC?

Find hourly flight availability from Panama City to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 29, 2025.
Get a feel of what it's like to fly with Southwest, Delta and United Airlines from Panama City to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,295 reviews

Comfort

8.0

Food

7.1

Crew

8.6

Overall

8.0

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,295 reviews
Southwest
8.0
Very good
4,295 reviews

Comfort

8.0

Food

7.1

Crew

8.6

Overall

8.0

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,929 reviews
Southwest
8.0
Very good
4,295 reviews

Comfort

8.0

Food

7.1

Crew

8.6

Overall

8.0

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,295 reviews

Comfort

8.0

Food

7.1

Crew

8.6

Overall

8.0

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,295 reviews

Comfort

8.0

Food

7.1

Crew

8.6

Overall

8.0

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Panama City to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to South Carolina?

    For a flight from Panama City to South Carolina, you will be flying from NW Florida Beaches. Panama City NW Florida Beaches (ECP) is just 16.0 mi from the center of the city.

  • What are the most popular routes from Panama City, Florida to South Carolina?

    Most travelers choose Panama City NW Florida Beaches - Charleston, Panama City NW Florida Beaches - Myrtle Beach Intl or Panama City NW Florida Beaches - Greenville when deciding on the best route from Panama City, Florida to South Carolina.

  • Can I find deals for flights from Panama City to South Carolina that include hotel bookings?

    Yes. In addition to deals on Panama City to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to South Carolina.

  • Can I find deals for business class flights from Panama City to South Carolina?

    Yes. Cheapflights offers flight deals from Panama City to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to South Carolina (average of $217). Flying from Panama City, Florida to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama City to South Carolina

Discover the top 2 airlines that operate flights from Panama City to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$206Average$479FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$214Average$436FlexibilityNo cancel feeOn-time71%

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