HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$48+ Cheap flights from Michigan to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — CHS
Feb 23 — Mar 21
Mon 2/23
Mon 3/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Michigan to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Michigan to South Carolina

Cheapest flights from Michigan to South Carolina
Explore the most affordable flight options available from Michigan to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 24, 2026.

This Super.com deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:55 pm
ORD
-
CLT
Nonstop2h 02m
Frontier
Mon 3/1610:42 pm
CLT
-
ORD
Nonstop2h 31m
Frontier
Deal found 1/22$66
This Kiwi.com deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:55 pm
ORD
-
CLT
Nonstop2h 02m
Frontier
Mon 3/1610:42 pm
CLT
-
ORD
Nonstop2h 31m
Frontier
Deal found 1/22$80
This Kiwi.com deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:55 pm
ORD
-
CLT
Nonstop2h 02m
Frontier
Mon 3/910:58 pm
CLT
-
ORD
Nonstop2h 31m
Frontier
Deal found 1/22$85
This CheapOair deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2712:01 pm
ORD
-
CLT
Nonstop2h 02m
Frontier
Mon 3/23:52 pm
CLT
-
ORD
Nonstop2h 31m
Frontier
Deal found 1/23$86
This Kiwi.com deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/54:19 pm
ORD
-
CLT
Nonstop2h 06m
Frontier
Mon 2/98:20 pm
CLT
-
ORD
Nonstop2h 22m
Frontier
Deal found 1/22$91
This Super.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/64:19 pm
ORD
-
CLT
Nonstop2h 06m
Frontier
Sun 2/88:49 pm
CLT
-
ORD
Nonstop2h 22m
Frontier
Deal found 1/23$97
This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:09 am
DTW
-
CHS
1 stop10h 46m
Spirit Airlines
Tue 2/245:00 pm
CHS
-
DTW
1 stop7h 09m
Spirit Airlines
Deal found 1/23$122
This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/225:09 am
DTW
-
CHS
1 stop10h 46m
Spirit Airlines
Wed 2/255:00 pm
CHS
-
DTW
1 stop7h 09m
Spirit Airlines
Deal found 1/23$123
This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/75:00 am
DTW
-
CHS
1 stop11h 10m
Spirit Airlines
Mon 2/95:05 pm
CHS
-
DTW
1 stop7h 14m
Spirit Airlines
Deal found 1/23$125
This Expedia deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/115:00 am
DTW
-
MYR
1 stop9h 42m
Spirit Airlines
Wed 2/183:59 pm
MYR
-
DTW
1 stop5h 55m
Spirit Airlines
Deal found 1/23$126
This CheapOair deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:09 am
DTW
-
CHS
1 stop10h 46m
Spirit Airlines
Thu 2/265:00 pm
CHS
-
DTW
1 stop7h 09m
Spirit Airlines
Deal found 1/22$128
This Expedia deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:09 am
DTW
-
MYR
1 stop5h 53m
Spirit Airlines
Wed 2/253:59 pm
MYR
-
DTW
1 stop5h 55m
Spirit Airlines
Deal found 1/23$129

Find flight deals from Michigan to South Carolina

Keep the following information in mind while searching for Michigan to South Carolina flight deals. Data was last updated January 24, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$66
(Super.com)

One-way from

$48
(Booking.com)

Popular in

December

Cheapest in

August

Average price

$242

Good round-trip deal

$300 or less

Good one-way deal

$234 or less
Provider with most accurate pricing for Detroit (DTT)-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit (DTT)-Myrtle Beach Intl flights.
Search Deals
From Michigan to South Carolina
Search Deals
One-way flight from Michigan to South Carolina
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($77 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Michigan to South Carolina.
Search Deals
Price to beat on a one-way flight from Michigan to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Michigan to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 24, 2026.
Use the filters below to find and compare flights from Michigan to South Carolina that are best for you.

Fly from

Michigan

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Fri 2/6

4:19 pm-7:25 pm

Nonstop2h 06m

Charlotte Douglas

Sun 2/8

8:49 pm-10:11 pm

Nonstop2h 22m

$98

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Fri 2/13

5:24 pm-8:26 pm

Nonstop2h 02m

Charlotte Douglas

Sun 2/15

3:37 pm-5:08 pm

Nonstop2h 31m

$121

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 2/5

4:19 pm-7:25 pm

Nonstop2h 06m

Charlotte Douglas

Mon 2/9

8:20 pm-9:42 pm

Nonstop2h 22m

$128

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sat 2/14

8:05 am-5:48 pm

1 stop8h 43m

Charlotte Douglas

Tue 2/17

5:54 pm-12:40 am

1 stop7h 46m

$137

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 2/19

7:00 am-9:32 am

1 stop25h 32m

Charlotte Douglas

Sun 2/22

10:50 am-7:54 am

1 stop22h 04m

$138

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Thu 2/26

7:05 am-9:07 am

Nonstop2h 02m

Charlotte Douglas

Tue 3/3

6:00 am-7:52 am

Nonstop1h 52m

$139

DetroitMyrtle Beach

DTW - MYR

DTWMYR

Detroit Metropolitan Wayne County

Fri 2/13

10:59 pm-11:57 pm

1 stop24h 58m

Myrtle Beach Intl

Tue 2/17

6:15 am-7:49 am

1 stop25h 34m

$140

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Thu 2/19

7:45 pm-9:32 pm

Nonstop1h 47m

Charlotte Douglas

Tue 2/24

1:11 pm-3:03 pm

Nonstop1h 52m

$149

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Fri 2/13

10:59 pm-11:59 pm

1 stop25h 00m

Charlotte Douglas

Mon 2/16

9:07 pm-7:49 am

1 stop10h 42m

$156

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Sat 2/21

10:06 am-12:08 pm

Nonstop2h 02m

Charlotte Douglas

Wed 2/25

5:25 am-9:30 am

1 stop4h 05m

$159

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/23

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Michigan to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Michigan with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Michigan to South Carolina

What is the cheapest month to book a flight from Michigan to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Michigan to South Carolina (average of $78). Flying from Michigan to South Carolina in December is currently the most expensive (average of $174). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MI to SC?

Find hourly flight availability from Michigan to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 24, 2026.

When flying from Michigan to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 33% versus a flight at noon.

What is the cheapest day to fly from Michigan to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Michigan to South Carolina. Price data was last updated on January 17, 2026.

Travelers seeking maximum savings on their Michigan to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Michigan to South Carolina

Explore weekly flight availability from Michigan to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 24, 2026.

The most flights from USMI to USSC are scheduled on a Monday (7 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 24, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Michigan to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,268 reviews

Boarding

8.1

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,268 reviews
Southwest
8.0
Very good
4,268 reviews

Boarding

8.1

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,110 reviews
Southwest
8.0
Very good
4,268 reviews

Boarding

8.1

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,194 reviews
Southwest
8.0
Very good
4,268 reviews

Boarding

8.1

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,192 reviews
Southwest
8.0
Very good
4,268 reviews

Boarding

8.1

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Spirit Airlines
6.3
Okay
8,370 reviews
Southwest
8.0
Very good
4,268 reviews

Boarding

8.1

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Michigan to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Michigan to South Carolina?

    A quick flight from Michigan to South Carolina can take about 2h 02m. Frontier provides one of the quickest options available for as low as $139. Airlines will cover a distance of 500 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Michigan to South Carolina one-way?

    The cheapest airlines for a one-way flight from Michigan to South Carolina are Spirit Airlines ($34), Allegiant Air ($44), and American Airlines ($98).

  • Can I find deals for flights from Michigan to South Carolina that include hotel bookings?

    Yes. In addition to deals on Michigan to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Michigan to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Michigan to South Carolina.

  • Can I find deals for business class flights from Michigan to South Carolina?

    Yes. Cheapflights offers flight deals from Michigan to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Michigan to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Michigan to South Carolina (average of $78). Flying from Michigan to South Carolina in December is currently the most expensive (average of $174). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Michigan to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Fort Lauderdale flights
Newark to Miami flights
John F Kennedy Intl to Miami flights
LaGuardia to Miami flights
Newark to Fort Lauderdale flights
LaGuardia to Fort Lauderdale flights
Newark to West Palm Beach flights
John F Kennedy Intl to West Palm Beach flights
John F Kennedy Intl to Orlando flights
John F Kennedy Intl to Los Angeles flights
John F Kennedy Intl to Las Vegas flights
Newark to Las Vegas flights
Newark to Orlando flights
John F Kennedy Intl to Dallas/Fort Worth flights
O'Hare Intl to Sky Harbor Intl flights
Los Angeles to John F Kennedy Intl flights
Boston to Fort Lauderdale flights
Los Angeles to Seattle flights
Dallas/Fort Worth to John F Kennedy Intl flights
John F Kennedy Intl to Tampa flights
O'Hare Intl to Las Vegas flights
Newark to Los Angeles flights
Newark to Tampa flights
Minneapolis to Sky Harbor Intl flights
Seattle to Las Vegas flights
LaGuardia to Orlando flights
Dulles Intl to Miami flights
Seattle to Los Angeles flights
Detroit to Orlando flights
Dallas/Fort Worth to LaGuardia flights
LaGuardia to Tampa flights
Boston to Miami flights
Los Angeles to Honolulu flights
John F Kennedy Intl to Sky Harbor Intl flights
San Francisco to Las Vegas flights
O'Hare Intl to Dallas/Fort Worth flights
San Francisco to John F Kennedy Intl flights
John F Kennedy Intl to San Francisco flights
Dallas/Fort Worth to Seattle flights
Boston to Tampa flights
Dallas/Fort Worth to Las Vegas flights
Detroit to Fort Lauderdale flights
Reagan-National to Miami flights
Minneapolis to Orlando flights
Newark to Sky Harbor Intl flights
LaGuardia to West Palm Beach flights
Los Angeles to Newark flights
Newark to Dallas/Fort Worth flights
Baltimore to Fort Lauderdale flights
O'Hare Intl to Fort Lauderdale flights

Top 6 airlines flying from Michigan to South Carolina

Discover the top 6 airlines that operate flights from Michigan to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$64Average$159FlexibilityNo cancel feeOn-time65%
Allegiant AirCheapest$78Average$104FlexibilityNo cancel feeOn-time88%
DeltaCheapest$125Average$384FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$173Average$377FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$197Average$363FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$207Average$356FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.