$59+ Cheap flights from Michigan to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — CHS
Apr 22 — Apr 291
Round-trip
1 adult, Economy
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Find cheap flights from Michigan to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Michigan to South Carolina
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Cheapest flights from Michigan to South CarolinaExplore the most affordable flight options available from Michigan to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.
Explore the most affordable flight options available from Michigan to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/192:00 pm
ORD
- CLT
Nonstop2h 16m
Frontier
Sun 4/264:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/18![Frontier logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 4/274:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/21![Frontier logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/251:27 pm
ORD
- CLT
1 stop7h 31m
Frontier
Mon 4/274:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/20![Frontier logo]()
$122
This Super.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:16 pm
ORD
- CLT
Nonstop2h 15m
Frontier
Fri 4/244:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/18![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:01 pm
ORD
- CLT
1 stop4h 52m
Multiple Airlines
Thu 4/1610:24 pm
CLT
- ORD
Nonstop2h 20m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$127
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:16 pm
ORD
- CLT
Nonstop2h 15m
Frontier
Mon 4/274:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/22![Frontier logo]()
$128
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:25 am
ORD
- CLT
1 stop10h 30m
Frontier
Thu 4/1610:24 pm
CLT
- ORD
Nonstop2h 20m
Frontier
Deal found 3/20![Frontier logo]()
$129
This Super.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Sun 5/34:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/22![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:15 pm
ORD
- CLT
1 stop12h 55m
Multiple Airlines
Thu 4/234:19 pm
CLT
- ORD
Nonstop2h 34m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$133
This Frontier deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:09 pm
DTW
- CLT
1 stop4h 28m
Frontier
Mon 4/2010:13 am
CLT
- DTW
1 stop9h 35m
Frontier
Deal found 3/21![Frontier logo]()
$160
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:14 am
MDW
- CLT
1 stop7h 36m
Frontier
Sun 4/197:19 pm
CLT
- MDW
1 stop13h 45m
Frontier
Deal found 3/20![Frontier logo]()
$160
This Cheapflightsfares deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:05 am
DTW
- CLT
1 stop5h 06m
Spirit Airlines
Sat 3/2811:12 am
CLT
- DTW
1 stop6h 43m
Spirit Airlines
Deal found 3/20![Spirit Airlines logo]()
$162
Best flights from Michigan to South CarolinaDiscover carefully curated flight deals from Michigan to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 23, 2026.
Discover carefully curated flight deals from Michigan to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 23, 2026.
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:05 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Wed 4/296:20 pm
CLT
- MDW
Nonstop2h 05m
Southwest
Deal found 3/18![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:35 pm
ORD
- CLT
Nonstop2h 10m
United Airlines
Mon 5/188:05 am
CLT
- ORD
Nonstop2h 18m
United Airlines
Deal found 3/18![United Airlines logo]()
$237
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:30 am
ORD
- GSP
1 stop5h 35m
Delta
Sat 6/67:20 am
GSP
- ORD
1 stop6h 36m
Delta
Deal found 3/19![Delta logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:07 pm
DTW
- SAV
2 stops24h 03m
Multiple Airlines
Tue 3/314:50 pm
SAV
- DTW
1 stop15h 56m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$327
This Contour deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3011:20 am
ORD
- CLT
1 stop4h 40m
Contour
Fri 4/36:05 pm
CLT
- ORD
1 stop23h 10m
Contour
Deal found 3/21![Contour logo]()
$350
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:15 am
MDW
- CLT
1 stop5h 15m
Southwest
Wed 4/227:35 am
CLT
- MDW
Nonstop2h 10m
Southwest
Deal found 3/18![Southwest logo]()
$247
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:55 pm
ORD
- GSP
Nonstop2h 05m
United Airlines
Fri 6/56:00 am
GSP
- ORD
Nonstop2h 20m
United Airlines
Deal found 3/21![United Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/183:40 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Sun 4/198:50 pm
CLT
- MDW
1 stop4h 30m
Southwest
Deal found 3/19![Southwest logo]()
$247
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:45 am
ORD
- GSP
1 stop7h 30m
Delta
Mon 5/47:59 pm
GSP
- ORD
1 stop5h 00m
Delta
Deal found 3/18![Delta logo]()
$282
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:45 pm
ORD
- GSP
Nonstop2h 02m
United Airlines
Sun 4/196:30 am
GSP
- ORD
Nonstop2h 24m
United Airlines
Deal found 3/17![United Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:05 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Mon 5/48:30 pm
CLT
- MDW
1 stop4h 00m
Southwest
Deal found 3/18![Southwest logo]()
$247
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:07 am
ORD
- GSP
1 stop4h 01m
Delta
Sat 6/67:20 am
GSP
- ORD
1 stop4h 09m
Delta
Deal found 3/19![Delta logo]()
$282
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:00 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Thu 4/308:30 pm
CLT
- MDW
1 stop4h 00m
Southwest
Deal found 3/18![Southwest logo]()
$247
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:55 pm
ORD
- SAV
1 stop5h 31m
United Airlines
Sat 5/167:15 pm
SAV
- ORD
1 stop5h 29m
United Airlines
Deal found 3/18![United Airlines logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/319:16 am
DTW
- MYR
1 stop5h 28m
Multiple Airlines
Sun 6/76:47 pm
MYR
- DTW
2 stops47h 11m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$361
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/315:30 am
ORD
- MYR
1 stop4h 09m
Delta
Wed 6/311:32 am
MYR
- ORD
1 stop5h 57m
Delta
Deal found 3/17![Delta logo]()
$306
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:40 pm
DTW
- CLT
2 stops8h 00m
Southwest
Mon 6/16:15 am
CLT
- DTW
1 stop6h 05m
Southwest
Deal found 3/22![Southwest logo]()
$255
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/233:50 pm
MDW
- CLT
1 stop5h 50m
Southwest
Mon 4/278:30 pm
CLT
- MDW
1 stop4h 00m
Southwest
Deal found 3/21![Southwest logo]()
$257
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2312:23 pm
DTW
- CLT
1 stop5h 50m
Delta
Wed 5/276:05 am
CLT
- DTW
Nonstop1h 46m
Delta
Deal found 3/22![Delta logo]()
$313
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2510:40 am
ORD
- MYR
1 stop5h 29m
United Airlines
Tue 4/283:15 pm
MYR
- ORD
Nonstop2h 31m
United Airlines
Deal found 3/17![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:29 am
DTW
- CLT
1 stop5h 58m
Delta
Sat 6/61:05 pm
CLT
- DTW
Nonstop1h 47m
Delta
Deal found 3/19![Delta logo]()
$313
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/811:55 am
MDW
- CLT
2 stops5h 50m
Southwest
Sun 5/108:50 pm
CLT
- MDW
1 stop4h 30m
Southwest
Deal found 3/17![Southwest logo]()
$262
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:45 pm
ORD
- CLT
Nonstop2h 18m
United Airlines
Thu 4/910:34 am
CLT
- ORD
Nonstop2h 26m
United Airlines
Deal found 3/19![United Airlines logo]()
$318
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:00 pm
DTW
- CLT
1 stop5h 18m
Delta
Tue 5/266:05 am
CLT
- DTW
Nonstop1h 46m
Delta
Deal found 3/21![Delta logo]()
$313
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/41:00 pm
ORD
- GSP
1 stop4h 59m
United Airlines
Wed 4/85:41 pm
GSP
- ORD
Nonstop2h 20m
United Airlines
Deal found 3/19![United Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:05 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Tue 5/197:35 am
CLT
- MDW
Nonstop2h 10m
Southwest
Deal found 3/21![Southwest logo]()
$267
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/79:00 am
ORD
- SAV
1 stop8h 15m
United Airlines
Wed 4/85:45 am
SAV
- ORD
1 stop6h 42m
United Airlines
Deal found 3/17![United Airlines logo]()
$322
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:16 pm
DTW
- CLT
Nonstop1h 44m
Delta
Tue 5/59:36 am
CLT
- DTW
Nonstop1h 54m
Delta
Deal found 3/22![Delta logo]()
$323
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:05 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Thu 4/237:00 pm
CLT
- MDW
Nonstop2h 05m
Southwest
Deal found 3/19![Southwest logo]()
$281
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:16 pm
DTW
- CLT
Nonstop1h 44m
Delta
Mon 4/276:00 am
CLT
- DTW
Nonstop1h 44m
Delta
Deal found 3/21![Delta logo]()
$323
Last-minute flights from Michigan to South CarolinaDiscover last-minute flight deals from Michigan to South Carolina. Data last updated March 23, 2026 and is based on user searches.
Discover last-minute flight deals from Michigan to South Carolina. Data last updated March 23, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:58 pm
DTW
- CLT
1 stop15h 55m
Frontier
Sun 4/127:49 pm
CLT
- DTW
1 stop15h 09m
Frontier
Deal found 3/22![Frontier logo]()
$160
This Expedia deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/78:45 am
DTW
- CLT
1 stop11h 03m
Multiple Airlines
Sun 4/127:49 pm
CLT
- DTW
1 stop15h 09m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$157
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:25 am
ORD
- CLT
1 stop10h 30m
Frontier
Thu 4/1610:24 pm
CLT
- ORD
Nonstop2h 20m
Frontier
Deal found 3/20![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:01 pm
ORD
- CLT
1 stop4h 52m
Multiple Airlines
Thu 4/1610:24 pm
CLT
- ORD
Nonstop2h 20m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$127
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:14 am
MDW
- CLT
1 stop7h 36m
Frontier
Sun 4/197:19 pm
CLT
- MDW
1 stop13h 45m
Frontier
Deal found 3/20![Frontier logo]()
$160
This Super.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:16 pm
ORD
- CLT
Nonstop2h 15m
Frontier
Fri 4/244:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/18![Frontier logo]()
$126
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:16 pm
ORD
- CLT
Nonstop2h 15m
Frontier
Mon 4/274:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/22![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/181:27 pm
ORD
- CLT
1 stop7h 31m
Frontier
Mon 4/205:17 pm
CLT
- ORD
Nonstop2h 33m
Frontier
Deal found 3/22![Frontier logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/192:00 pm
ORD
- CLT
Nonstop2h 16m
Frontier
Sun 4/264:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/18![Frontier logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 4/274:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/21![Frontier logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/251:27 pm
ORD
- CLT
1 stop7h 31m
Frontier
Mon 4/274:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/20![Frontier logo]()
$122
This Super.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Sun 5/34:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/22![Frontier logo]()
$132
One-way flights from Michigan to South CarolinaSearch for one-way flight options from Michigan to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 23, 2026.
Search for one-way flight options from Michigan to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 23, 2026.
This Orbitz deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/24:17 pm
DTW
- CLT
1 stop8h 21m
Spirit Airlines
Deal found 3/18![Spirit Airlines logo]()
$59
This Priceline deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:22 am
DTW
- CLT
1 stop7h 38m
Spirit Airlines
Deal found 3/18![Spirit Airlines logo]()
$68
This Super.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:02 pm
ORD
- CLT
Nonstop2h 10m
Frontier
Deal found 3/20![Frontier logo]()
$68
This Super.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/21:27 pm
ORD
- CLT
1 stop7h 31m
Frontier
Deal found 3/20![Frontier logo]()
$69
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/199:53 am
DTW
- CLT
1 stop7h 30m
Frontier
Deal found 3/22![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:14 am
MDW
- CLT
1 stop7h 36m
Frontier
Deal found 3/19![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/181:27 pm
ORD
- CLT
1 stop7h 31m
Frontier
Deal found 3/20![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:30 am
MDW
- CLT
1 stop15h 23m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$73
This Frontier deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:31 pm
ORD
- CLT
Nonstop2h 17m
Frontier
Deal found 3/21![Frontier logo]()
$74
This Super.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:27 pm
DTW
- CLT
1 stop18h 29m
Frontier
Deal found 3/22![Frontier logo]()
$75
This Super.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:20 am
ORD
- CLT
1 stop15h 31m
Frontier
Deal found 3/22![Frontier logo]()
$75
This Flightnetwork deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:25 am
ORD
- CLT
1 stop10h 30m
Frontier
Deal found 3/20![Frontier logo]()
$76
Find flight deals from Michigan to South Carolina
Keep the following information in mind while searching for Michigan to South Carolina flight deals. Data was last updated March 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $117 (Kiwi.com) |
One-way from | $59 (Orbitz) |
Popular in | January |
Cheapest in | August |
Average price | $424 |
Good round-trip deal | $134 or less |
Good one-way deal | $208 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Michigan to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Fri 4/24
7:05 pm-10:00 pm
Nonstop1h 55m
Charlotte Douglas
Wed 4/29
6:20 pm-7:25 pm
Nonstop2h 05m
$237
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Fri 5/15
9:35 pm-12:45 am
Nonstop2h 10m
Charlotte Douglas
Mon 5/18
8:05 am-9:23 am
Nonstop2h 18m
$237
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Sun 4/19
8:15 am-2:30 pm
1 stop5h 15m
Charlotte Douglas
Wed 4/22
7:35 am-8:45 am
Nonstop2h 10m
$247
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Sat 4/18
3:40 pm-6:35 pm
Nonstop1h 55m
Charlotte Douglas
Sun 4/19
8:50 pm-12:20 am
1 stop4h 30m
$247
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Fri 5/1
7:05 pm-10:00 pm
Nonstop1h 55m
Charlotte Douglas
Mon 5/4
8:30 pm-11:30 pm
1 stop4h 00m
$247
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Tue 4/28
6:00 pm-8:55 pm
Nonstop1h 55m
Charlotte Douglas
Thu 4/30
8:30 pm-11:30 pm
1 stop4h 00m
$247
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Wed 5/27
1:40 pm-9:40 pm
2 stops8h 00m
Charlotte Douglas
Mon 6/1
6:15 am-12:20 pm
1 stop6h 05m
$255
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Thu 4/23
3:50 pm-10:40 pm
1 stop5h 50m
Charlotte Douglas
Mon 4/27
8:30 pm-11:30 pm
1 stop4h 00m
$257
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Fri 5/8
11:55 am-6:45 pm
2 stops5h 50m
Charlotte Douglas
Sun 5/10
8:50 pm-12:20 am
1 stop4h 30m
$262
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Thu 5/14
7:05 pm-10:00 pm
Nonstop1h 55m
Charlotte Douglas
Tue 5/19
7:35 am-8:45 am
Nonstop2h 10m
$267
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Michigan to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Michigan with our price prediction graph.
ORD-CLT
DTW-CLT
MDW-CLT
ORD-MYR
DTW-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to South Carolina
USMI-USSC
ORD-CLT
DTW-CLT
MDW-CLT
ORD-MYR
What is the cheapest month to book a flight from Michigan to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Michigan to South Carolina (average of $78). Flying from Michigan to South Carolina in January is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to SC?
Find hourly flight availability from Michigan to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 23, 2026.
When flying from Michigan to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 27% versus a flight in the afternoon.
What is the cheapest day to fly from Michigan to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Michigan to South Carolina. Price data was last updated on March 14, 2026.
Travelers seeking maximum savings on their Michigan to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Michigan to South Carolina
Explore weekly flight availability from Michigan to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 23, 2026.
The most flights from USMI to USSC are scheduled on a Monday (6 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (3 on average).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 23, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Michigan to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Overall
8.0
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Boarding
8.1
Overall
8.0
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Boarding
8.1
Overall
8.0
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Boarding
8.1
Overall
8.0
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Boarding
8.1
Overall
8.0
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Boarding
8.1
Overall
8.0
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Michigan to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Michigan to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Michigan to South Carolina by cabin class
Find flights from Michigan to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Michigan and South Carolina flights
Browse other Michigan and South Carolina flight options. Last updated on March 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Michigan after your stay in South Carolina
Michigan to South Carolina flights
Consider these flights traveling from Michigan to South Carolina.
Top 6 airlines flying from Michigan to South Carolina
Discover the top 6 airlines that operate flights from Michigan to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$64 | Average$161 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$78 | Average$98 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$115 | Average$379 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$197 | Average$348 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$207 | Average$391 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$208 | Average$382 | FlexibilityNo cancel fee | On-time69% |