$70+ Cheap flights from Michigan to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — CHS
May 23 — May 301
Round-trip
1 adult, Economy
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Find cheap flights from Michigan to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Michigan to South Carolina
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Cheapest flights from Michigan to South CarolinaExplore the most affordable flight options available from Michigan to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
Explore the most affordable flight options available from Michigan to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
This Super.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Sun 4/264:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/18![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:37 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Wed 4/2912:50 pm
CLT
- ORD
1 stop12h 34m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:37 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Mon 4/279:54 pm
CLT
- ORD
1 stop24h 23m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$150
This CheapOair deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:05 am
ORD
- CLT
1 stop7h 49m
Multiple Airlines
Mon 5/44:40 pm
CLT
- ORD
Nonstop2h 34m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Tue 4/2812:50 pm
CLT
- ORD
1 stop9h 27m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$152
This Frontier deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Thu 4/304:19 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/18![Frontier logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Thu 4/3012:50 pm
CLT
- ORD
1 stop9h 27m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$154
This Expedia deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 5/48:09 pm
CLT
- ORD
1 stop28h 04m
Frontier
Deal found 4/19![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:37 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Tue 4/2812:50 pm
CLT
- ORD
1 stop9h 27m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:30 am
ORD
- CLT
1 stop9h 18m
Frontier
Mon 5/117:58 pm
CLT
- ORD
1 stop28h 15m
Frontier
Deal found 4/18![Frontier logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:37 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Wed 4/2912:50 pm
CLT
- ORD
1 stop12h 34m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$159
This Expedia deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:55 am
DTW
- CLT
1 stop8h 30m
Multiple Airlines
Thu 5/289:07 pm
CLT
- DTW
1 stop11h 56m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$165
Best flights from Michigan to South CarolinaDiscover carefully curated flight deals from Michigan to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
Discover carefully curated flight deals from Michigan to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:15 pm
ORD
- CLT
Nonstop2h 14m
United Airlines
Sat 5/309:55 am
CLT
- ORD
Nonstop2h 15m
United Airlines
Deal found 4/21![United Airlines logo]()
$184
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:40 pm
ORD
- CLT
1 stop6h 00m
Southwest
Sat 5/307:05 am
CLT
- ORD
2 stops9h 25m
Southwest
Deal found 4/22![Southwest logo]()
$210
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/278:59 pm
ORD
- GSP
Nonstop1h 59m
American Airlines
Tue 6/307:20 am
GSP
- ORD
Nonstop2h 26m
American Airlines
Deal found 4/22![American Airlines logo]()
$255
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:06 pm
ORD
- MYR
1 stop4h 52m
Delta
Tue 6/24:07 pm
MYR
- ORD
1 stop7h 20m
Delta
Deal found 4/21![Delta logo]()
$278
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:15 pm
ORD
- CLT
Nonstop2h 14m
United Airlines
Sat 5/306:00 am
CLT
- ORD
1 stop6h 49m
United Airlines
Deal found 4/22![United Airlines logo]()
$194
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:15 pm
ORD
- CLT
1 stop4h 44m
United Airlines
Mon 5/185:28 pm
CLT
- ORD
Nonstop2h 25m
United Airlines
Deal found 4/22![United Airlines logo]()
$211
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/122:40 pm
ORD
- GSP
1 stop6h 00m
Southwest
Thu 5/146:25 am
GSP
- ORD
1 stop7h 25m
Southwest
Deal found 4/22![Southwest logo]()
$248
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:15 pm
ORD
- CLT
Nonstop2h 14m
United Airlines
Fri 6/58:05 am
CLT
- ORD
Nonstop2h 17m
United Airlines
Deal found 4/22![United Airlines logo]()
$228
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/211:35 am
ORD
- GSP
1 stop7h 47m
Delta
Tue 7/73:35 pm
GSP
- ORD
1 stop6h 21m
Delta
Deal found 4/19![Delta logo]()
$282
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:40 pm
ORD
- GSP
1 stop6h 35m
Southwest
Tue 5/126:45 am
GSP
- ORD
1 stop7h 05m
Southwest
Deal found 4/20![Southwest logo]()
$269
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/52:59 pm
ORD
- GSP
1 stop4h 14m
Delta
Mon 6/85:44 am
GSP
- ORD
1 stop3h 54m
Delta
Deal found 4/22![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:15 pm
ORD
- CLT
Nonstop2h 14m
United Airlines
Tue 6/98:05 am
CLT
- ORD
Nonstop2h 17m
United Airlines
Deal found 4/19![United Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/211:35 am
ORD
- GSP
1 stop7h 47m
Delta
Sun 7/58:52 am
GSP
- ORD
1 stop6h 37m
Delta
Deal found 4/18![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:40 pm
ORD
- GSP
1 stop6h 55m
Southwest
Mon 6/16:25 am
GSP
- ORD
2 stops10h 05m
Southwest
Deal found 4/21![Southwest logo]()
$300
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/279:49 am
ORD
- HHH
1 stop4h 44m
Delta
Wed 6/34:16 pm
HHH
- ORD
1 stop7h 20m
Delta
Deal found 4/17![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:50 pm
ORD
- GSP
Nonstop2h 08m
United Airlines
Wed 5/205:45 pm
GSP
- ORD
Nonstop2h 20m
United Airlines
Deal found 4/21![United Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:40 pm
DTW
- CLT
2 stops8h 10m
Southwest
Sun 5/248:35 am
CLT
- DTW
2 stops11h 45m
Southwest
Deal found 4/21![Southwest logo]()
$301
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:10 am
ORD
- HHH
1 stop6h 23m
Delta
Tue 6/912:11 pm
HHH
- ORD
1 stop5h 23m
Delta
Deal found 4/21![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:15 am
ORD
- MYR
Nonstop2h 27m
United Airlines
Sat 5/2311:25 am
MYR
- ORD
Nonstop2h 45m
United Airlines
Deal found 4/21![United Airlines logo]()
$273
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:10 am
ORD
- HHH
1 stop6h 23m
Delta
Mon 6/812:11 pm
HHH
- ORD
2 stops7h 18m
Delta
Deal found 4/21![Delta logo]()
$294
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/168:35 am
DTW
- SAV
2 stops9h 25m
Southwest
Sat 5/237:00 pm
SAV
- DTW
1 stop4h 10m
Southwest
Deal found 4/21![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:15 pm
ORD
- CLT
Nonstop2h 14m
United Airlines
Sun 6/286:15 am
CLT
- ORD
Nonstop2h 24m
United Airlines
Deal found 4/20![United Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:50 am
DTW
- CLT
1 stop4h 25m
Southwest
Sat 5/233:50 pm
CLT
- DTW
1 stop5h 35m
Southwest
Deal found 4/21![Southwest logo]()
$325
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:05 am
ORD
- CHS
1 stop6h 42m
Delta
Sun 6/75:10 am
CHS
- ORD
1 stop4h 28m
Delta
Deal found 4/21![Delta logo]()
$300
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:00 am
ORD
- CHS
Nonstop2h 23m
United Airlines
Wed 6/37:47 pm
CHS
- ORD
1 stop4h 39m
United Airlines
Deal found 4/22![United Airlines logo]()
$293
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/208:05 pm
DTW
- CLT
Nonstop1h 50m
Delta
Tue 6/236:00 am
CLT
- DTW
Nonstop1h 45m
Delta
Deal found 4/22![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
ORD
- CHS
2 stops12h 10m
Southwest
Mon 5/116:00 am
CHS
- ORD
2 stops10h 30m
Southwest
Deal found 4/19![Southwest logo]()
$355
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:55 pm
ORD
- CHS
1 stop5h 04m
United Airlines
Wed 5/136:00 am
CHS
- ORD
1 stop4h 37m
United Airlines
Deal found 4/21![United Airlines logo]()
$303
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:30 am
ORD
- CLT
1 stop7h 05m
Delta
Mon 7/612:19 pm
CLT
- ORD
1 stop7h 23m
Delta
Deal found 4/19![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:55 am
DTW
- MYR
1 stop6h 15m
Southwest
Fri 9/118:10 am
MYR
- DTW
2 stops10h 25m
Southwest
Deal found 4/17![Southwest logo]()
$364
Last-minute flights from Michigan to South CarolinaDiscover last-minute flight deals from Michigan to South Carolina. Data last updated April 23, 2026 and is based on user searches.
Discover last-minute flight deals from Michigan to South Carolina. Data last updated April 23, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Sun 4/264:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/18![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Tue 4/2812:50 pm
CLT
- ORD
1 stop9h 27m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Thu 4/3012:50 pm
CLT
- ORD
1 stop9h 27m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:37 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Wed 4/2912:50 pm
CLT
- ORD
1 stop12h 34m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:37 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Mon 4/279:54 pm
CLT
- ORD
1 stop24h 23m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$150
This Frontier deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Thu 4/304:19 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/18![Frontier logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:37 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Tue 4/2812:50 pm
CLT
- ORD
1 stop9h 27m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:37 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Wed 4/2912:50 pm
CLT
- ORD
1 stop12h 34m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$159
This Expedia deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 5/48:09 pm
CLT
- ORD
1 stop28h 04m
Frontier
Deal found 4/19![Frontier logo]()
$155
This CheapOair deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:05 am
ORD
- CLT
1 stop7h 49m
Multiple Airlines
Mon 5/44:40 pm
CLT
- ORD
Nonstop2h 34m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:30 am
ORD
- CLT
1 stop9h 18m
Frontier
Mon 5/117:58 pm
CLT
- ORD
1 stop28h 15m
Frontier
Deal found 4/18![Frontier logo]()
$158
This Expedia deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:55 am
DTW
- CLT
1 stop8h 30m
Multiple Airlines
Thu 5/289:07 pm
CLT
- DTW
1 stop11h 56m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$165
One-way flights from Michigan to South CarolinaSearch for one-way flight options from Michigan to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
Search for one-way flight options from Michigan to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1712:55 pm
DTW
- CLT
1 stop4h 53m
Frontier
Deal found 4/20![Frontier logo]()
$70
This Super.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/164:14 pm
DTW
- CLT
1 stop25h 34m
Frontier
Deal found 4/21![Frontier logo]()
$75
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1512:42 pm
DTW
- CLT
1 stop5h 06m
Frontier
Deal found 4/18![Frontier logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:55 pm
ORD
- CLT
1 stop23h 48m
Frontier
Deal found 4/22![Frontier logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:52 am
ORD
- MYR
1 stop11h 44m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:37 pm
ORD
- CLT
1 stop19h 41m
Frontier
Deal found 4/20![Frontier logo]()
$83
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:00 pm
ORD
- CLT
Nonstop2h 11m
United Airlines
Deal found 4/21![United Airlines logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:05 am
ORD
- MYR
1 stop11h 31m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$88
This Mytrip deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
DTW
- CLT
1 stop8h 11m
Spirit Airlines
Deal found 4/20![Spirit Airlines logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:05 am
ORD
- CLT
1 stop8h 06m
Spirit Airlines
Deal found 4/22![Spirit Airlines logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:52 am
ORD
- GSP
1 stop30h 06m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$89
This Super.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:55 pm
DTW
- CLT
1 stop4h 53m
Frontier
Deal found 4/19![Frontier logo]()
$89
Find flight deals from Michigan to South Carolina
Keep the following information in mind while searching for Michigan to South Carolina flight deals. Data was last updated April 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $150 (Expedia) |
One-way from | $70 (Frontier) |
Popular in | March |
Cheapest in | August |
Average price | $329 |
Good round-trip deal | $100 or less |
Good one-way deal | $50 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Michigan to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Tue 5/26
6:15 pm-9:29 pm
Nonstop2h 14m
Charlotte Douglas
Sat 5/30
9:55 am-11:10 am
Nonstop2h 15m
$184
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Wed 5/27
6:15 pm-9:29 pm
Nonstop2h 14m
Charlotte Douglas
Sat 5/30
6:00 am-11:49 am
1 stop6h 49m
$194
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Wed 5/27
2:40 pm-9:40 pm
1 stop6h 00m
Charlotte Douglas
Sat 5/30
7:05 am-3:30 pm
2 stops9h 25m
$210
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Sat 5/16
6:15 pm-11:59 pm
1 stop4h 44m
Charlotte Douglas
Mon 5/18
5:28 pm-6:53 pm
Nonstop2h 25m
$211
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Wed 6/3
6:15 pm-9:29 pm
Nonstop2h 14m
Charlotte Douglas
Fri 6/5
8:05 am-9:22 am
Nonstop2h 17m
$228
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Tue 5/12
2:40 pm-9:40 pm
1 stop6h 00m
Greenville
Thu 5/14
6:25 am-12:50 pm
1 stop7h 25m
$248
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Sat 6/27
8:59 pm-11:58 pm
Nonstop1h 59m
Greenville
Tue 6/30
7:20 am-8:46 am
Nonstop2h 26m
$255
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Tue 6/2
6:15 pm-9:29 pm
Nonstop2h 14m
Charlotte Douglas
Tue 6/9
8:05 am-9:22 am
Nonstop2h 17m
$259
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Mon 5/11
2:40 pm-10:15 pm
1 stop6h 35m
Greenville
Tue 5/12
6:45 am-12:50 pm
1 stop7h 05m
$269
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Fri 5/15
7:50 pm-10:58 pm
Nonstop2h 08m
Greenville
Wed 5/20
5:45 pm-7:05 pm
Nonstop2h 20m
$269
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Michigan to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Michigan with our price prediction graph.
ORD-CLT
ORD-CHS
ORD-MYR
ORD-SAV
ORD-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to South Carolina
USMI-USSC
ORD-CLT
ORD-CHS
ORD-MYR
ORD-SAV
What is the cheapest month to book a flight from Michigan to South Carolina?
Currently, September is the cheapest month in which you can book a flight from Michigan to South Carolina (average of $63). Flying from Michigan to South Carolina in April is currently the most expensive (average of $637). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to SC?
Find hourly flight availability from Michigan to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 23, 2026.
When flying from Michigan to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 20% versus a flight in the afternoon.
What is the cheapest day to fly from Michigan to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Michigan to South Carolina. Price data was last updated on April 18, 2026.
Travelers seeking maximum savings on their Michigan to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from Michigan to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 23, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Michigan to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Michigan to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Michigan to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Michigan to South Carolina by cabin class
Find flights from Michigan to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Michigan and South Carolina flights
Browse other Michigan and South Carolina flight options. Last updated on April 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Michigan after your stay in South Carolina
Michigan to South Carolina flights
Consider these flights traveling from Michigan to South Carolina.
Top 6 airlines flying from Michigan to South Carolina
Discover the top 6 airlines that operate flights from Michigan to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$64 | Average$156 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$78 | Average$100 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$108 | Average$384 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$173 | Average$389 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$198 | Average$354 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$208 | Average$398 | FlexibilityNo cancel fee | On-time69% |