$60+ Cheap flights from Michigan to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — CHS
Jun 24 — Jul 11
Round-trip
1 adult, Economy
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Find cheap flights from Michigan to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Michigan to South Carolina
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Cheapest flights from Michigan to South CarolinaExplore the most affordable flight options available from Michigan to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 25, 2026.
Explore the most affordable flight options available from Michigan to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:05 am
ORD
- CLT
1 stop12h 02m
Frontier
Mon 7/136:41 pm
CLT
- ORD
1 stop18h 34m
Frontier
Deal found 5/23![Frontier logo]()
$227
This Frontier deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:05 am
ORD
- CLT
1 stop12h 02m
Frontier
Wed 8/1212:24 pm
CLT
- ORD
1 stop11h 46m
Frontier
Deal found 5/24![Frontier logo]()
$230
This Booking.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/19:48 pm
ORD
- CLT
1 stop19h 31m
Frontier
Wed 7/85:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Deal found 5/24![Frontier logo]()
$232
This Trip.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/89:28 am
ORD
- CLT
1 stop8h 14m
Frontier
Wed 7/155:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Deal found 5/25![Frontier logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:46 pm
ORD
- CLT
1 stop18h 07m
Frontier
Tue 7/285:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Deal found 5/20![Frontier logo]()
$237
This CheapOair deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:29 pm
ORD
- CLT
1 stop21h 42m
Frontier
Wed 9/25:59 pm
CLT
- ORD
1 stop7h 43m
Frontier
Deal found 5/24![Frontier logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:05 am
ORD
- CLT
1 stop12h 02m
Frontier
Tue 7/145:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Deal found 5/23![Frontier logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/179:48 pm
ORD
- CLT
1 stop19h 31m
Frontier
Tue 6/2310:01 am
CLT
- ORD
1 stop15h 47m
Frontier
Deal found 5/20![Frontier logo]()
$243
This Frontier deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:00 am
ORD
- CLT
1 stop4h 51m
Frontier
Tue 9/1512:10 pm
CLT
- ORD
1 stop8h 45m
Frontier
Deal found 5/24![Frontier logo]()
$244
This Booking.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/244:59 pm
ORD
- CLT
1 stop17h 35m
Frontier
Sat 6/271:09 pm
CLT
- ORD
1 stop6h 38m
Frontier
Deal found 5/23![Frontier logo]()
$245
This Mytrip deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:46 pm
ORD
- CLT
1 stop18h 07m
Frontier
Sat 7/255:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Deal found 5/23![Frontier logo]()
$246
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/168:30 am
ORD
- MYR
Nonstop2h 23m
American Airlines
Tue 6/2312:23 pm
MYR
- ORD
Nonstop2h 40m
American Airlines
Deal found 5/23![American Airlines logo]()
$257
Best flights from Michigan to South CarolinaDiscover carefully curated flight deals from Michigan to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 25, 2026.
Discover carefully curated flight deals from Michigan to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 25, 2026.
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:10 pm
ORD
- GSP
Nonstop2h 07m
United Airlines
Sat 6/275:43 pm
GSP
- ORD
Nonstop2h 17m
United Airlines
Deal found 5/21![United Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/118:49 pm
ORD
- GSP
Nonstop1h 59m
American Airlines
Mon 6/157:14 pm
GSP
- ORD
1 stop5h 16m
American Airlines
Deal found 5/20![American Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:01 am
ORD
- CLT
1 stop4h 25m
Delta
Tue 7/76:00 am
CLT
- ORD
1 stop5h 37m
Delta
Deal found 5/24![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:35 am
DTW
- CLT
1 stop4h 25m
Southwest
Sat 7/46:30 am
CLT
- DTW
2 stops9h 00m
Southwest
Deal found 5/24![Southwest logo]()
$335
This JetBlue deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/249:42 am
ORD
- SAV
1 stop7h 50m
JetBlue
Mon 8/310:56 am
SAV
- ORD
1 stop6h 20m
JetBlue
Deal found 5/24![JetBlue logo]()
$432
This United Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:55 am
ORD
- GSP
Nonstop2h 00m
United Airlines
Tue 7/286:10 am
GSP
- ORD
Nonstop2h 20m
United Airlines
Deal found 5/25![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:02 am
ORD
- GSP
1 stop4h 53m
Delta
Sun 8/2311:10 am
GSP
- ORD
1 stop6h 14m
Delta
Deal found 5/22![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:55 am
ORD
- GSP
Nonstop2h 00m
United Airlines
Wed 6/246:10 am
GSP
- ORD
Nonstop2h 19m
United Airlines
Deal found 5/20![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/201:49 pm
ORD
- GSP
1 stop4h 27m
Delta
Wed 6/248:52 am
GSP
- ORD
1 stop4h 44m
Delta
Deal found 5/21![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:12 pm
ORD
- CLT
1 stop4h 47m
United Airlines
Fri 5/296:50 pm
CLT
- ORD
Nonstop2h 38m
United Airlines
Deal found 5/22![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2311:23 am
ORD
- CHS
1 stop4h 55m
Delta
Sat 6/276:24 pm
CHS
- ORD
1 stop6h 40m
Delta
Deal found 5/22![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/32:15 pm
DTW
- CLT
1 stop6h 05m
Southwest
Mon 10/52:35 pm
CLT
- DTW
2 stops7h 10m
Southwest
Deal found 5/24![Southwest logo]()
$356
This United Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:29 am
ORD
- CLT
Nonstop2h 14m
United Airlines
Sat 7/187:44 pm
CLT
- ORD
1 stop4h 47m
United Airlines
Deal found 5/23![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/168:08 am
ORD
- HHH
1 stop6h 24m
Delta
Tue 6/234:15 pm
HHH
- ORD
1 stop7h 19m
Delta
Deal found 5/23![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:35 pm
DTW
- CLT
2 stops5h 50m
Southwest
Mon 9/147:40 am
CLT
- DTW
1 stop6h 25m
Southwest
Deal found 5/21![Southwest logo]()
$356
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 pm
ORD
- CHS
Nonstop2h 04m
United Airlines
Tue 10/206:43 pm
CHS
- ORD
Nonstop2h 44m
United Airlines
Deal found 5/24![United Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:30 am
ORD
- CHS
1 stop6h 34m
Delta
Mon 9/214:10 pm
CHS
- ORD
1 stop5h 45m
Delta
Deal found 5/24![Delta logo]()
$294
This Southwest deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:35 am
DTW
- MYR
1 stop4h 30m
Southwest
Sat 10/1010:50 am
MYR
- DTW
2 stops9h 00m
Southwest
Deal found 5/22![Southwest logo]()
$370
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 pm
ORD
- CHS
Nonstop2h 04m
United Airlines
Tue 10/204:58 pm
CHS
- ORD
Nonstop2h 30m
United Airlines
Deal found 5/24![United Airlines logo]()
$290
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:46 pm
ORD
- GSP
1 stop4h 30m
Delta
Sat 6/137:10 am
GSP
- ORD
1 stop4h 25m
Delta
Deal found 5/23![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/161:25 pm
DTW
- CLT
2 stops8h 40m
Southwest
Fri 6/194:40 pm
CLT
- DTW
1 stop5h 45m
Southwest
Deal found 5/20![Southwest logo]()
$374
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:25 am
ORD
- CHS
Nonstop2h 02m
United Airlines
Mon 9/284:58 pm
CHS
- ORD
Nonstop2h 30m
United Airlines
Deal found 5/22![United Airlines logo]()
$296
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:30 am
DTW
- CLT
1 stop4h 30m
Southwest
Mon 10/52:35 pm
CLT
- DTW
2 stops7h 10m
Southwest
Deal found 5/21![Southwest logo]()
$375
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/161:15 pm
ORD
- CHS
1 stop6h 26m
Delta
Tue 10/205:30 am
CHS
- ORD
1 stop5h 37m
Delta
Deal found 5/24![Delta logo]()
$310
This United Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:05 am
ORD
- CHS
Nonstop2h 30m
United Airlines
Tue 6/167:47 pm
CHS
- ORD
1 stop4h 39m
United Airlines
Deal found 5/23![United Airlines logo]()
$300
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:01 am
ORD
- CLT
1 stop4h 25m
Delta
Mon 7/65:30 am
CLT
- ORD
1 stop5h 43m
Delta
Deal found 5/22![Delta logo]()
$312
This Southwest deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:05 am
DTW
- CLT
2 stops10h 45m
Southwest
Thu 6/254:40 pm
CLT
- DTW
2 stops7h 25m
Southwest
Deal found 5/23![Southwest logo]()
$379
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:55 pm
ORD
- SAV
Nonstop2h 24m
United Airlines
Mon 8/2412:59 pm
SAV
- ORD
Nonstop2h 36m
United Airlines
Deal found 5/20![United Airlines logo]()
$303
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/21:40 pm
ORD
- GSP
1 stop7h 08m
Delta
Sun 7/56:45 am
GSP
- ORD
1 stop6h 51m
Delta
Deal found 5/25![Delta logo]()
$314
This Southwest deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:30 am
DTW
- CLT
1 stop4h 25m
Southwest
Mon 8/171:05 pm
CLT
- DTW
2 stops7h 45m
Southwest
Deal found 5/22![Southwest logo]()
$382
Last-minute flights from Michigan to South CarolinaDiscover last-minute flight deals from Michigan to South Carolina. Data last updated May 25, 2026 and is based on user searches.
Discover last-minute flight deals from Michigan to South Carolina. Data last updated May 25, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/248:00 am
ORD
- GSP
Nonstop2h 04m
American Airlines
Sat 6/137:20 am
GSP
- ORD
Nonstop2h 26m
American Airlines
Deal found 5/22![American Airlines logo]()
$262
This Booking.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:59 pm
ORD
- CLT
1 stop22h 31m
Frontier
Sun 6/147:14 pm
CLT
- ORD
1 stop26h 29m
Frontier
Deal found 5/20![Frontier logo]()
$252
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:03 am
ORD
- MYR
Nonstop2h 33m
United Airlines
Wed 6/1710:34 am
MYR
- ORD
1 stop4h 55m
United Airlines
Deal found 5/20![United Airlines logo]()
$260
This Priceline deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1612:31 pm
ORD
- CLT
1 stop10h 10m
Frontier
Sat 6/205:59 pm
CLT
- ORD
1 stop7h 49m
Frontier
Deal found 5/23![Frontier logo]()
$249
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/168:30 am
ORD
- MYR
Nonstop2h 23m
American Airlines
Tue 6/2312:23 pm
MYR
- ORD
Nonstop2h 40m
American Airlines
Deal found 5/23![American Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/179:48 pm
ORD
- CLT
1 stop19h 31m
Frontier
Tue 6/2310:01 am
CLT
- ORD
1 stop15h 47m
Frontier
Deal found 5/20![Frontier logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:29 pm
ORD
- CLT
1 stop18h 08m
Frontier
Mon 6/225:59 pm
CLT
- ORD
1 stop7h 49m
Frontier
Deal found 5/20![Frontier logo]()
$256
This Booking.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2312:31 pm
ORD
- CLT
1 stop10h 10m
Frontier
Wed 6/246:10 am
CLT
- ORD
1 stop10h 43m
Frontier
Deal found 5/25![Frontier logo]()
$230
This Booking.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/244:59 pm
ORD
- CLT
1 stop17h 35m
Frontier
Wed 7/16:10 am
CLT
- ORD
1 stop10h 43m
Frontier
Deal found 5/24![Frontier logo]()
$232
This Booking.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/244:59 pm
ORD
- CLT
1 stop17h 35m
Frontier
Sat 6/271:09 pm
CLT
- ORD
1 stop6h 38m
Frontier
Deal found 5/23![Frontier logo]()
$245
This Expedia deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2611:20 am
ORD
- CLT
1 stop4h 40m
Multiple Airlines
Tue 7/75:57 pm
CLT
- ORD
1 stop7h 52m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$255
This Frontier deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/278:00 pm
ORD
- CLT
1 stop11h 42m
Frontier
Wed 7/16:10 am
CLT
- ORD
1 stop10h 43m
Frontier
Deal found 5/24![Frontier logo]()
$244
One-way flights from Michigan to South CarolinaSearch for one-way flight options from Michigan to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 25, 2026.
Search for one-way flight options from Michigan to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 25, 2026.
This Trip.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1612:42 pm
DTW
- CLT
1 stop8h 53m
Frontier
Deal found 5/20![Frontier logo]()
$60
This Trip.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/912:42 pm
DTW
- CLT
1 stop8h 53m
Frontier
Deal found 5/20![Frontier logo]()
$85
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:15 am
ORD
- MYR
Nonstop2h 18m
United Airlines
Deal found 5/22![United Airlines logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:10 am
DTW
- CHS
2 stops8h 58m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:46 pm
ORD
- CLT
1 stop18h 07m
Frontier
Deal found 5/20![Frontier logo]()
$108
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:35 am
ORD
- MYR
1 stop5h 29m
Delta
Deal found 5/22![Delta logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:44 pm
ORD
- CHS
1 stop14h 54m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:05 am
ORD
- MYR
1 stop24h 45m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/309:12 am
DTW
- MYR
1 stop8h 33m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:30 pm
ORD
- CHS
1 stop14h 08m
Multiple Airlines
Deal found 5/23![Multiple Airlines logo]()
$113
This Super.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1512:50 pm
DTW
- CLT
1 stop5h 13m
Frontier
Deal found 5/24![Frontier logo]()
$114
This Super.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:29 am
ORD
- CLT
1 stop11h 04m
Frontier
Deal found 5/23![Frontier logo]()
$114
Find flight deals from Michigan to South Carolina
Keep the following information in mind while searching for Michigan to South Carolina flight deals. Data was last updated May 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $227 (Kiwi.com) |
One-way from | $60 (Trip.com) |
Popular in | March |
Cheapest in | August |
Average price | $424 |
Good round-trip deal | $90 or less |
Good one-way deal | $218 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 25, 2026.
Use the filters below to find and compare flights from Michigan to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Sat 6/20
6:10 pm-9:17 pm
Nonstop2h 07m
Greenville
Sat 6/27
5:43 pm-7:00 pm
Nonstop2h 17m
$269
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Wed 7/22
6:55 am-9:55 am
Nonstop2h 00m
Greenville
Tue 7/28
6:10 am-7:30 am
Nonstop2h 20m
$269
Quickest round-trip
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Wed 6/17
6:55 am-9:55 am
Nonstop2h 00m
Greenville
Wed 6/24
6:10 am-7:29 am
Nonstop2h 19m
$269
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Thu 5/28
6:12 pm-11:59 pm
1 stop4h 47m
Charlotte Douglas
Fri 5/29
6:50 pm-8:28 pm
Nonstop2h 38m
$269
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Sat 7/18
6:29 am-9:43 am
Nonstop2h 14m
Charlotte Douglas
Sat 7/18
7:44 pm-11:31 pm
1 stop4h 47m
$269
ChicagoCharleston
ORD - CHS
ORDCHS
Chicago O'Hare Intl
Sat 10/17
6:00 pm-9:04 pm
Nonstop2h 04m
Charleston
Tue 10/20
6:43 pm-8:27 pm
Nonstop2h 44m
$274
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Thu 6/11
8:49 pm-11:48 pm
Nonstop1h 59m
Greenville
Mon 6/15
7:14 pm-11:30 pm
1 stop5h 16m
$279
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Tue 6/30
7:01 am-12:26 pm
1 stop4h 25m
Charlotte Douglas
Tue 7/7
6:00 am-10:37 am
1 stop5h 37m
$279
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Fri 8/21
8:02 am-1:55 pm
1 stop4h 53m
Greenville
Sun 8/23
11:10 am-4:24 pm
1 stop6h 14m
$289
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Sat 6/20
1:49 pm-7:16 pm
1 stop4h 27m
Greenville
Wed 6/24
8:52 am-12:36 pm
1 stop4h 44m
$289
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Michigan to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Michigan with our price prediction graph.
DTW-CLT
ORD-MYR
DTW-CHS
ORD-CLT
ORD-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to South Carolina
USMI-USSC
DTW-CLT
ORD-MYR
DTW-CHS
ORD-CLT
What is the cheapest month to book a flight from Michigan to South Carolina?
Currently, July is the cheapest month in which you can book a flight from Michigan to South Carolina (average of $61). Flying from Michigan to South Carolina in June is currently the most expensive (average of $1,186). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to SC?
Find hourly flight availability from Michigan to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 25, 2026.
When flying from Michigan to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 25% versus a flight in the afternoon.
Weekly flight availability from Michigan to South Carolina
Explore weekly flight availability from Michigan to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 25, 2026.
The most flights from USMI to USSC are scheduled on a Monday (13 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (12 on average).
How much does it cost to fly round-trip from Michigan to South Carolina?
How far ahead should I book a flight from Michigan to South Carolina?
The price you pay for your flight from Michigan to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 33 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from Michigan to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Michigan to South Carolina. Price data was last updated on May 16, 2026.
Travelers seeking maximum savings on their Michigan to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated May 25, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Michigan to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Spirit Airlines
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Michigan to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Michigan to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Michigan to South Carolina by cabin class
Find flights from Michigan to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Michigan and South Carolina flights
Browse other Michigan and South Carolina flight options. Last updated on May 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Michigan after your stay in South Carolina
Michigan to South Carolina flights
Consider these flights traveling from Michigan to South Carolina.
Top 6 airlines flying from Michigan to South Carolina
Discover the top 6 airlines that operate flights from Michigan to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$64 | Average$154 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$78 | Average$100 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$125 | Average$398 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$173 | Average$386 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$198 | Average$368 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$199 | Average$405 | FlexibilityNo cancel fee | On-time69% |