$118+ Cheap flights from Michigan to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — CHS
Nov 25 — Dec 21
Round-trip
1 adult, Economy
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Find cheap flights from Michigan to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Michigan to South Carolina
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Cheapest flights from Michigan to South CarolinaExplore the most affordable flight options available from Michigan to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
Explore the most affordable flight options available from Michigan to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:05 pm -
1 stop12h 33m
Thu 12/106:45 am -
2 stops12h 21m
Deal found 10/24![Multiple Airlines logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:00 am -
1 stop23h 38m
Mon 12/144:57 pm -
2 stops46h 19m
Deal found 10/23![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:53 pm -
1 stop17h 45m
Sat 12/56:40 am -
1 stop16h 45m
Deal found 10/26![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:29 pm -
1 stop15h 25m
Thu 11/1910:12 am -
2 stops13h 25m
Deal found 10/23![Multiple Airlines logo]()
$226
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:33 pm -
1 stop11h 55m
Tue 12/84:03 pm -
1 stop19h 18m
Deal found 10/23![Multiple Airlines logo]()
$233
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:30 am -
1 stop4h 35m
Sat 12/58:20 am -
1 stop4h 40m
Deal found 10/22![Southwest logo]()
$236
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:10 pm -
1 stop4h 55m
Sat 12/128:20 am -
1 stop4h 40m
Deal found 10/23![Southwest logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:31 pm -
2 stops18h 07m
Sun 12/610:15 pm -
1 stop13h 06m
Deal found 10/24![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:33 pm -
2 stops11h 59m
Mon 12/142:42 pm -
1 stop20h 39m
Deal found 10/25![Multiple Airlines logo]()
$238
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:50 pm -
Nonstop2h 12m
Sat 12/56:47 pm -
Nonstop2h 13m
Deal found 10/23![Delta logo]()
$239
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:15 am -
1 stop9h 25m
Thu 11/265:35 am -
2 stops10h 55m
Deal found 10/21![Southwest logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:33 pm -
1 stop11h 55m
Mon 12/71:53 pm -
1 stop21h 28m
Deal found 10/25![Multiple Airlines logo]()
$248
Best flights from Michigan to South CarolinaDiscover carefully curated flight deals from Michigan to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
Discover carefully curated flight deals from Michigan to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:30 am -
1 stop4h 35m
Sat 12/58:20 am -
2 stops9h 05m
Deal found 10/22![Southwest logo]()
$241
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:05 am -
Nonstop2h 20m
Wed 12/92:04 pm -
1 stop7h 16m
Deal found 10/25![Delta logo]()
$249
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/195:25 am -
2 stops8h 41m
Sat 1/239:46 am -
1 stop6h 29m
Deal found 10/21![United Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:28 pm -
1 stop8h 58m
Tue 11/108:12 am -
1 stop4h 04m
Deal found 10/21![American Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:15 am -
1 stop9h 25m
Thu 11/265:35 am -
2 stops10h 55m
Deal found 10/21![Southwest logo]()
$247
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:34 pm -
2 stops8h 13m
Thu 11/196:20 am -
1 stop5h 00m
Deal found 10/22![United Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:20 am -
1 stop6h 30m
Mon 12/143:20 pm -
1 stop7h 45m
Deal found 10/26![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/138:35 am -
2 stops10h 35m
Sun 1/178:00 am -
1 stop4h 20m
Deal found 10/23![Southwest logo]()
$293
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:15 pm -
1 stop5h 49m
Mon 12/146:47 pm -
Nonstop2h 13m
Deal found 10/23![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/128:35 am -
2 stops9h 40m
Tue 1/1911:10 am -
2 stops10h 45m
Deal found 10/21![Southwest logo]()
$305
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:05 am -
1 stop6h 49m
Sat 1/92:59 pm -
2 stops7h 25m
Deal found 10/26![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:50 pm -
1 stop3h 43m
Wed 11/255:10 pm -
1 stop6h 44m
Deal found 10/22![Delta logo]()
$324
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:55 pm -
1 stop7h 22m
Mon 11/167:13 am -
1 stop7h 00m
Deal found 10/23![American Airlines logo]()
$400
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:00 am -
1 stop7h 15m
Mon 12/78:10 am -
2 stops12h 20m
Deal found 10/23![Southwest logo]()
$308
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/262:15 pm -
1 stop3h 26m
Sun 1/315:40 am -
1 stop6h 17m
Deal found 10/22![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:15 am -
2 stops8h 02m
Sat 11/1410:16 am -
1 stop4h 03m
Deal found 10/23![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:55 am -
1 stop5h 58m
Sat 11/141:55 pm -
1 stop6h 38m
Deal found 10/22![American Airlines logo]()
$406
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:30 am -
1 stop5h 11m
Mon 12/76:57 pm -
1 stop4h 52m
Deal found 10/24![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:35 am -
1 stop5h 10m
Thu 11/198:05 am -
2 stops10h 35m
Deal found 10/25![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:08 am -
1 stop5h 13m
Sat 11/148:30 am -
1 stop5h 13m
Deal found 10/26![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/183:51 pm -
1 stop5h 58m
Mon 12/217:41 pm -
1 stop4h 14m
Deal found 10/26![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/136:49 am -
2 stops9h 00m
Thu 3/186:18 am -
1 stop5h 00m
Deal found 10/26![American Airlines logo]()
$445
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:08 am -
1 stop5h 13m
Wed 11/117:00 pm -
1 stop4h 57m
Deal found 10/22![United Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/135:30 am -
1 stop4h 35m
Sat 12/197:10 pm -
1 stop5h 20m
Deal found 10/25![Southwest logo]()
$345
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/159:32 am -
1 stop7h 21m
Wed 12/165:34 pm -
1 stop6h 25m
Deal found 10/21![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:25 am -
1 stop7h 01m
Thu 12/3110:00 am -
1 stop6h 44m
Deal found 10/24![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/1511:13 am -
1 stop4h 40m
Sun 1/174:25 pm -
2 stops17h 13m
Deal found 10/23![American Airlines logo]()
$473
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:50 am -
2 stops10h 35m
Wed 11/258:05 am -
2 stops11h 15m
Deal found 10/26![Southwest logo]()
$356
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/213:50 pm -
Nonstop2h 12m
Mon 12/286:47 pm -
Nonstop2h 13m
Deal found 10/25![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1610:44 am -
2 stops13h 15m
Thu 12/176:32 pm -
1 stop5h 27m
Deal found 10/23![United Airlines logo]()
$374
Last-minute flights from Michigan to South CarolinaDiscover last-minute flight deals from Michigan to South Carolina. Data last updated October 26, 2026 and is based on user searches.
Discover last-minute flight deals from Michigan to South Carolina. Data last updated October 26, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:29 pm -
1 stop16h 44m
Fri 11/66:12 pm -
2 stops29h 25m
Deal found 10/26![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:29 pm -
1 stop16h 44m
Tue 11/104:03 pm -
1 stop7h 34m
Deal found 10/23![Multiple Airlines logo]()
$267
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:17 pm -
1 stop5h 42m
Tue 11/104:17 pm -
1 stop5h 39m
Deal found 10/22![Delta logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:29 pm -
1 stop26h 45m
Tue 11/171:21 pm -
2 stops10h 16m
Deal found 10/25![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:29 pm -
2 stops20h 55m
Thu 11/1210:13 pm -
1 stop25h 24m
Deal found 10/26![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:29 pm -
1 stop26h 45m
Sat 11/146:00 am -
2 stops17h 37m
Deal found 10/26![Multiple Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:53 pm -
2 stops13h 45m
Mon 11/164:57 pm -
1 stop6h 40m
Deal found 10/22![Multiple Airlines logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1611:04 am -
1 stop21h 34m
Wed 11/186:00 am -
1 stop27h 04m
Deal found 10/22![Multiple Airlines logo]()
$257
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:36 am -
1 stop3h 50m
Tue 11/248:44 pm -
1 stop3h 55m
Deal found 10/22![American Airlines logo]()
$261
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:36 am -
1 stop4h 46m
Thu 11/196:27 pm -
1 stop6h 12m
Deal found 10/22![American Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:29 pm -
1 stop15h 25m
Thu 11/1910:12 am -
2 stops13h 25m
Deal found 10/23![Multiple Airlines logo]()
$226
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:15 am -
1 stop9h 25m
Thu 11/265:35 am -
2 stops10h 55m
Deal found 10/21![Southwest logo]()
$247
One-way flights from Michigan to South CarolinaSearch for one-way flight options from Michigan to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
Search for one-way flight options from Michigan to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:20 am -
1 stop4h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Southwest logo]()
$118
This JetBlue deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/66:34 am -
1 stop5h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![JetBlue logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:29 pm -
1 stop16h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:29 pm -
1 stop26h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/89:33 pm -
1 stop11h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:29 pm -
1 stop17h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:29 pm -
1 stop26h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$133
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:13 am -
1 stop6h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:29 pm -
1 stop15h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$135
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:15 am -
1 stop6h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![United Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:16 am -
2 stops22h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:29 pm -
1 stop15h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$139
Find flight deals from Michigan to South Carolina
Keep the following information in mind while searching for Michigan to South Carolina flight deals. Data was last updated October 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $190 (Kiwi.com) |
One-way from | $118 (Southwest) |
Popular in | March |
Cheapest in | November |
Average price | $408 |
Good round-trip deal | $349 or less |
Good one-way deal | $278 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
Use the filters below to find and compare flights from Michigan to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitMyrtle Beach
DTW Detroit Metropolitan Wayne County - MYR Myrtle Beach Intl
DTWMYR
Detroit Metropolitan Wayne County
Mon 11/23
5:20 am-10:05 am
1 stop4h 45m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$118
DetroitCharleston
DTW Detroit Metropolitan Wayne County - CHS Charleston
DTWCHS
Detroit Metropolitan Wayne County
Wed 1/6
6:34 am-11:56 am
1 stop5h 22m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$118
DetroitMyrtle Beach
DTW Detroit Metropolitan Wayne County - MYR Myrtle Beach Intl
DTWMYR
Detroit Metropolitan Wayne County
Thu 12/10
6:00 am-1:15 pm
1 stop7h 15m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$118
Grand RapidsCharleston
GRR Grand Rapids Gerald R. Ford Intl - CHS Charleston
GRRCHS
Grand Rapids Gerald R. Ford Intl
Sat 12/12
5:13 am-11:29 am
1 stop6h 16m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$135
Grand RapidsGreenville
GRR Grand Rapids Gerald R. Ford Intl - GSP Greenville
GRRGSP
Grand Rapids Gerald R. Ford Intl
Wed 11/18
10:15 am-4:56 pm
1 stop6h 41m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
Grand RapidsCharleston
GRR Grand Rapids Gerald R. Ford Intl - CHS Charleston
GRRCHS
Grand Rapids Gerald R. Ford Intl
Sat 12/12
7:00 am-3:32 pm
2 stops8h 32m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
DetroitMyrtle Beach
DTW Detroit Metropolitan Wayne County - MYR Myrtle Beach Intl
DTWMYR
Detroit Metropolitan Wayne County
Wed 12/2
9:33 pm-3:03 pm
1 stop17h 30m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$141
Grand RapidsGreenville
GRR Grand Rapids Gerald R. Ford Intl - GSP Greenville
GRRGSP
Grand Rapids Gerald R. Ford Intl
Wed 11/18
11:00 am-6:10 pm
2 stops7h 10m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$141
Grand RapidsMyrtle Beach
GRR Grand Rapids Gerald R. Ford Intl - MYR Myrtle Beach Intl
GRRMYR
Grand Rapids Gerald R. Ford Intl
Sun 12/6
5:30 am-10:05 am
1 stop4h 35m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$145
Grand RapidsGreenville
GRR Grand Rapids Gerald R. Ford Intl - GSP Greenville
GRRGSP
Grand Rapids Gerald R. Ford Intl
Thu 12/24
8:00 am-2:03 pm
1 stop6h 03m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$151
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Michigan to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Michigan with our price prediction graph.
DTW-MYR
DTW-CHS
GRR-CHS
DTW-GSP
GRR-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to South Carolina
USMI-USSC
DTW-MYR
DTW-CHS
GRR-CHS
DTW-GSP
What is the cheapest month to book a flight from Michigan to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Michigan to South Carolina (average of $339). Flying from Michigan to South Carolina in March is currently the most expensive (average of $447). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to SC?
Find hourly flight availability from Michigan to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 26, 2026.
When flying from Michigan to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 12% versus a flight in the afternoon.
Weekly flight availability from Michigan to South Carolina
Explore weekly flight availability from Michigan to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated October 26, 2026.
The most flights from USMI to USSC are scheduled on a Sunday (9 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Michigan to South Carolina?
Airfare is below average for this route at the moment.
Michigan to South Carolina flights typically cost between $394 and $609 in December.The cheapest round-trip price found within the last 5 days was $190 on Multiple Airlines (Dec 7-Dec 10).
How far ahead should I book a flight from Michigan to South Carolina?
The price you pay for your flight from Michigan to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 86 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from Michigan to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Michigan to South Carolina. Price data was last updated on October 24, 2026.
Travelers seeking maximum savings on their Michigan to South Carolina flight should consider departing on Sunday mornings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 26, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Michigan to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Entertainment
7.4
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Entertainment
7.4
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Entertainment
7.4
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Entertainment
7.4
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Entertainment
7.4
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Entertainment
7.4
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Michigan to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Michigan to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Michigan to South Carolina by cabin class
Find flights from Michigan to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Michigan and South Carolina flights
Browse other Michigan and South Carolina flight options. Last updated on October 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Michigan after your stay in South Carolina
Michigan to South Carolina flights
Consider these flights traveling from Michigan to South Carolina.
Top 5 airlines flying from Michigan to South Carolina
Discover the top 5 airlines that operate flights from Michigan to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$80 | Average$115 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$172 | Average$422 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$188 | Average$438 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$235 | Average$405 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$238 | Average$407 | FlexibilityNo cancel fee | On-time71% |