South Carolina

$121+ Cheap flights from Michigan to South Carolina

DTW — CHS
Dec 9 — Dec 161
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1. Tell us where you want to go

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Cheap flight deals from Michigan to South Carolina

Cheapest flights from Michigan to South Carolina

Wed 12/92:53 pm -
1 stop17h 45m
Sat 12/126:40 am -
1 stop16h 45m
Deal found 11/5$237
Mon 12/79:33 pm -
1 stop12h 22m
Mon 12/141:53 pm -
1 stop21h 28m
Deal found 11/7$243
Tue 12/19:33 pm -
1 stop11h 55m
Fri 12/116:12 pm -
1 stop29h 13m
Deal found 11/4$249
Mon 11/164:29 pm -
1 stop17h 26m
Wed 11/182:42 pm -
1 stop8h 55m
Deal found 11/4$250
Fri 12/49:33 pm -
1 stop11h 55m
Fri 12/116:12 pm -
1 stop29h 13m
Deal found 11/6$251
Tue 12/19:33 pm -
1 stop11h 55m
Fri 12/46:12 pm -
1 stop29h 13m
Deal found 11/4$252
Fri 12/49:33 pm -
1 stop11h 55m
Mon 12/71:53 pm -
1 stop21h 28m
Deal found 11/5$254
Fri 12/49:33 pm -
1 stop11h 55m
Tue 12/84:03 pm -
1 stop19h 18m
Deal found 11/5$255
Tue 12/19:33 pm -
1 stop11h 55m
Tue 12/84:03 pm -
1 stop19h 18m
Deal found 11/5$256
Fri 12/49:33 pm -
2 stops16h 32m
Mon 12/74:57 pm -
1 stop18h 24m
Deal found 11/5$259
Sat 12/57:05 am -
1 stop6h 55m
Sat 12/122:57 pm -
2 stops7h 17m
Deal found 11/4$264
Sun 11/154:29 pm -
1 stop15h 44m
Mon 11/168:52 pm -
2 stops26h 45m
Deal found 11/6$267

Find flight deals from Michigan to South Carolina

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$221
(Kiwi.com)

One-way from

$121
(Kiwi.com)

Popular in

September

Cheapest in

November

Average price

$338

Good round-trip deal

$339 or less
Provider with most accurate pricing for Detroit (DTT)-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Detroit (DTT)-Myrtle Beach Intl flights.
From Michigan to South Carolina
One-way flight from Michigan to South Carolina
Highest demand for flights based on searches. 4% potential increase in price ($18 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Average for round-trip flights in November 2026
Price to beat on a round-trip flight from Michigan to South Carolina.

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Michigan to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitMyrtle Beach

DTW Detroit Metropolitan Wayne County - MYR Myrtle Beach Intl

DTWMYR

Detroit Metropolitan Wayne County

Fri 12/4

9:33 pm-9:28 am

1 stop11h 55m

Myrtle Beach Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$125

DetroitCharleston

DTW Detroit Metropolitan Wayne County - CHS Charleston

DTWCHS

Detroit Metropolitan Wayne County

Wed 1/6

6:34 am-11:56 am

1 stop5h 22m

Charleston

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$146

Grand RapidsCharleston

GRR Grand Rapids Gerald R. Ford Intl - CHS Charleston

GRRCHS

Grand Rapids Gerald R. Ford Intl

Mon 12/7

12:05 pm-12:31 pm

2 stops24h 26m

Charleston

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$147

DetroitMyrtle Beach

DTW Detroit Metropolitan Wayne County - MYR Myrtle Beach Intl

DTWMYR

Detroit Metropolitan Wayne County

Tue 12/15

8:50 am-6:25 pm

2 stops9h 35m

Myrtle Beach Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$150

DetroitCharleston

DTW Detroit Metropolitan Wayne County - CHS Charleston

DTWCHS

Detroit Metropolitan Wayne County

Mon 12/7

2:31 pm-12:31 pm

3 stops22h 00m

Charleston

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$165

Grand RapidsCharleston

GRR Grand Rapids Gerald R. Ford Intl - CHS Charleston

GRRCHS

Grand Rapids Gerald R. Ford Intl

Sat 2/13

5:35 pm-11:59 pm

1 stop6h 24m

Charleston

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$167

Grand RapidsCharleston

GRR Grand Rapids Gerald R. Ford Intl - CHS Charleston

GRRCHS

Grand Rapids Gerald R. Ford Intl

Sat 2/13

12:16 pm-11:59 pm

2 stops11h 43m

Charleston

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$172

Traverse CityCharleston

TVC Traverse City Cherry Capital - CHS Charleston

TVCCHS

Traverse City Cherry Capital

Thu 11/26

5:41 am-11:26 am

1 stop5h 45m

Charleston

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$175

Grand RapidsGreenville

GRR Grand Rapids Gerald R. Ford Intl - GSP Greenville

GRRGSP

Grand Rapids Gerald R. Ford Intl

Thu 12/24

1:43 pm-8:58 pm

1 stop7h 15m

Greenville

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$182

DetroitMyrtle Beach

DTW Detroit Metropolitan Wayne County - MYR Myrtle Beach Intl

DTWMYR

Detroit Metropolitan Wayne County

Mon 12/21

5:15 am-10:00 am

1 stop4h 45m

Myrtle Beach Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$185

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/6

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Michigan to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Michigan with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Michigan to South Carolina

What is the cheapest month to book a flight from Michigan to South Carolina?

Currently, January is the cheapest month in which you can book a flight from Michigan to South Carolina (average of $346). Flying from Michigan to South Carolina in March is currently the most expensive (average of $442). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MI to SC?

When flying from Michigan to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 9% versus a flight in the afternoon.

How much does it cost to fly round-trip from Michigan to South Carolina?

Airfare is below average for this route at the moment.
Michigan to South Carolina flights typically cost between $378 and $638 in January.
The cheapest round-trip price found within the last 5 days was $221 on Multiple Airlines (Jan 7-Jan 14).

How far ahead should I book a flight from Michigan to South Carolina?

The price you pay for your flight from Michigan to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 86 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest day to fly from Michigan to South Carolina?

Travelers seeking maximum savings on their Michigan to South Carolina flight should consider departing on Sunday mornings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Michigan to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Boarding

8.1

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Boarding

8.1

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Boarding

8.1

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Boarding

8.1

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Boarding

8.1

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Related info for your journey

  • How long is the flight from Michigan to South Carolina?

    A quick flight from Michigan to South Carolina can take about 4h 20m. United Airlines provides one of the quickest options available for as low as $329. Airlines will cover a distance of 637 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Michigan to South Carolina one-way?

    The cheapest airlines for a one-way flight from Michigan to South Carolina are Frontier ($95), Volaris ($109), and JetBlue ($163).

  • Can I find deals for flights from Michigan to South Carolina that include hotel bookings?

    Yes. In addition to deals on Michigan to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Michigan to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Michigan to South Carolina.

  • Can I find deals for business class flights from Michigan to South Carolina?

    Yes. Cheapflights offers flight deals from Michigan to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Michigan to South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Michigan to South Carolina (average of $346). Flying from Michigan to South Carolina in March is currently the most expensive (average of $442). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Michigan to South Carolina

Top 5 airlines flying from Michigan to South Carolina

AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$80Average$115FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$172Average$418FlexibilityNo cancel feeOn-time69%
DeltaCheapest$188Average$445FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$235Average$396FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$238Average$413FlexibilityNo cancel feeOn-time71%

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