$84+ Cheap flights from Michigan to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/19. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — CHS
Jul 21 — Jul 281
Round-trip
1 adult, Economy
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Find cheap flights from Michigan to South Carolina with Cheapflights
1. Tell us where you want to go
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Michigan to South Carolina
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Cheapest flights from Michigan to South CarolinaExplore the most affordable flight options available from Michigan to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.
Explore the most affordable flight options available from Michigan to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/810:18 am
DTW
- MYR
1 stop27h 27m
Multiple Airlines
Tue 9/1510:50 am
MYR
- DTW
1 stop26h 17m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$211
This Super.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:30 am
DTW
- CHS
1 stop8h 53m
JetBlue
Tue 7/215:19 pm
CHS
- DTW
1 stop5h 26m
JetBlue
Deal found 6/18![JetBlue logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:40 pm
DTW
- MYR
1 stop21h 59m
Multiple Airlines
Tue 8/253:53 pm
MYR
- DTW
1 stop25h 29m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$218
This Super.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:30 am
DTW
- CHS
1 stop8h 53m
JetBlue
Tue 8/111:05 pm
CHS
- DTW
1 stop9h 32m
JetBlue
Deal found 6/19![JetBlue logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:00 am
DTW
- CHS
1 stop29h 03m
Multiple Airlines
Mon 9/284:57 pm
CHS
- DTW
1 stop20h 10m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1911:00 am
DTW
- SAV
1 stop26h 00m
Multiple Airlines
Thu 9/249:15 am
SAV
- DTW
1 stop27h 52m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:08 am
DTW
- SAV
1 stop7h 47m
Multiple Airlines
Sat 8/1512:19 pm
SAV
- DTW
1 stop24h 36m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:08 am
DTW
- SAV
1 stop7h 47m
Multiple Airlines
Thu 8/1310:05 am
SAV
- DTW
1 stop26h 50m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/19:12 am
DTW
- SAV
1 stop8h 43m
Multiple Airlines
Wed 8/512:19 pm
SAV
- DTW
1 stop24h 36m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/810:18 am
DTW
- MYR
1 stop27h 27m
Multiple Airlines
Mon 9/141:48 pm
MYR
- DTW
1 stop23h 19m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/810:18 am
DTW
- MYR
1 stop27h 27m
Multiple Airlines
Wed 9/169:15 am
MYR
- DTW
1 stop27h 52m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/274:37 pm
DTW
- MYR
1 stop17h 13m
Multiple Airlines
Mon 8/318:41 pm
MYR
- DTW
1 stop16h 03m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$237
Best flights from Michigan to South CarolinaDiscover carefully curated flight deals from Michigan to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 21, 2026.
Discover carefully curated flight deals from Michigan to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 21, 2026.
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1910:54 am
MDW
- CLT
1 stop4h 18m
Delta
Tue 8/256:45 am
CLT
- MDW
1 stop6h 06m
Delta
Deal found 6/20![Delta logo]()
$267
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:25 am
ORD
- GSP
Nonstop2h 07m
United Airlines
Sat 8/292:18 pm
GSP
- ORD
Nonstop2h 12m
United Airlines
Deal found 6/16![United Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1912:35 pm
MDW
- CLT
2 stops5h 25m
Southwest
Tue 8/251:30 pm
CLT
- MDW
1 stop6h 15m
Southwest
Deal found 6/20![Southwest logo]()
$272
This JetBlue deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:30 am
DTW
- CHS
1 stop8h 53m
JetBlue
Mon 7/275:19 pm
CHS
- DTW
1 stop5h 26m
JetBlue
Deal found 6/19![JetBlue logo]()
$334
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:00 am
ORD
- CLT
1 stop4h 17m
Delta
Sat 8/291:17 pm
CLT
- ORD
1 stop4h 00m
Delta
Deal found 6/21![Delta logo]()
$267
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:27 am
ORD
- MYR
Nonstop2h 26m
United Airlines
Wed 8/1910:23 am
MYR
- ORD
1 stop7h 36m
United Airlines
Deal found 6/20![United Airlines logo]()
$276
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/199:29 am
MDW
- CLT
1 stop5h 37m
Delta
Mon 9/289:42 am
CLT
- MDW
1 stop3h 57m
Delta
Deal found 6/20![Delta logo]()
$278
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2811:00 am
ORD
- MYR
Nonstop2h 19m
United Airlines
Tue 8/410:34 am
MYR
- ORD
1 stop7h 28m
United Airlines
Deal found 6/19![United Airlines logo]()
$287
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:25 am
MDW
- CLT
Nonstop1h 55m
Southwest
Sun 8/237:10 am
CLT
- MDW
2 stops7h 35m
Southwest
Deal found 6/20![Southwest logo]()
$320
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:07 pm
ORD
- GSP
1 stop6h 40m
Delta
Mon 8/31:28 pm
GSP
- ORD
1 stop4h 23m
Delta
Deal found 6/17![Delta logo]()
$289
This JetBlue deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:00 am
ORD
- CLT
1 stop6h 15m
JetBlue
Tue 9/13:10 pm
CLT
- ORD
1 stop9h 34m
JetBlue
Deal found 6/17![JetBlue logo]()
$353
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/232:45 pm
MDW
- CLT
2 stops7h 35m
Southwest
Tue 7/2810:40 am
CLT
- MDW
1 stop4h 20m
Southwest
Deal found 6/16![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:05 am
ORD
- CHS
Nonstop2h 31m
United Airlines
Sun 8/166:30 am
CHS
- ORD
Nonstop2h 30m
United Airlines
Deal found 6/17![United Airlines logo]()
$313
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:30 am
ORD
- GSP
1 stop4h 10m
Delta
Sun 8/2311:10 am
GSP
- ORD
1 stop6h 07m
Delta
Deal found 6/17![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:55 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Mon 9/217:20 pm
CLT
- MDW
1 stop4h 00m
Southwest
Deal found 6/18![Southwest logo]()
$327
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1211:00 am
ORD
- MYR
Nonstop2h 19m
United Airlines
Wed 7/153:15 pm
MYR
- ORD
Nonstop2h 34m
United Airlines
Deal found 6/17![United Airlines logo]()
$317
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:35 am
ORD
- GSP
1 stop6h 26m
Delta
Sun 7/267:10 am
GSP
- ORD
1 stop6h 53m
Delta
Deal found 6/21![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:40 am
MDW
- CLT
2 stops9h 40m
Southwest
Mon 8/1011:50 am
CLT
- MDW
2 stops9h 20m
Southwest
Deal found 6/18![Southwest logo]()
$329
This JetBlue deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:40 am
ORD
- SAV
1 stop7h 52m
JetBlue
Wed 7/2210:56 am
SAV
- ORD
1 stop7h 38m
JetBlue
Deal found 6/17![JetBlue logo]()
$433
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:00 am
MDW
- CLT
Nonstop2h 10m
Southwest
Thu 8/137:40 am
CLT
- MDW
2 stops8h 45m
Southwest
Deal found 6/17![Southwest logo]()
$332
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/411:15 am
ORD
- CLT
1 stop4h 39m
Delta
Tue 7/71:17 pm
CLT
- ORD
1 stop6h 12m
Delta
Deal found 6/16![Delta logo]()
$305
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:42 am
ORD
- CLT
1 stop4h 36m
United Airlines
Mon 9/216:00 am
CLT
- ORD
1 stop4h 38m
United Airlines
Deal found 6/18![United Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:15 pm
MDW
- CLT
Nonstop2h 00m
Southwest
Wed 7/153:10 pm
CLT
- MDW
Nonstop2h 00m
Southwest
Deal found 6/19![Southwest logo]()
$333
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:30 am
ORD
- CLT
1 stop7h 05m
Delta
Tue 7/72:22 pm
CLT
- ORD
1 stop7h 11m
Delta
Deal found 6/16![Delta logo]()
$305
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:30 am
ORD
- CLT
Nonstop2h 14m
United Airlines
Tue 7/147:44 pm
CLT
- ORD
1 stop4h 47m
United Airlines
Deal found 6/21![United Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/61:20 pm
DTW
- CLT
2 stops8h 30m
Southwest
Tue 8/1111:10 am
CLT
- DTW
2 stops9h 20m
Southwest
Deal found 6/19![Southwest logo]()
$337
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:08 pm
DTW
- SAV
Nonstop2h 11m
Delta
Tue 9/226:00 pm
SAV
- DTW
Nonstop2h 12m
Delta
Deal found 6/18![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:45 pm
ORD
- CLT
Nonstop2h 15m
United Airlines
Sun 9/206:00 am
CLT
- ORD
1 stop4h 38m
United Airlines
Deal found 6/16![United Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:55 am
MDW
- CLT
1 stop5h 30m
Southwest
Sun 9/207:10 am
CLT
- MDW
2 stops7h 40m
Southwest
Deal found 6/19![Southwest logo]()
$341
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/302:07 pm
ORD
- GSP
1 stop6h 41m
Delta
Sun 7/56:45 am
GSP
- ORD
1 stop4h 28m
Delta
Deal found 6/20![Delta logo]()
$312
Last-minute flights from Michigan to South CarolinaDiscover last-minute flight deals from Michigan to South Carolina. Data last updated June 21, 2026 and is based on user searches.
Discover last-minute flight deals from Michigan to South Carolina. Data last updated June 21, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/58:52 pm
ORD
- CLT
1 stop12h 04m
Frontier
Wed 8/125:57 pm
CLT
- ORD
1 stop7h 36m
Frontier
Deal found 6/20![Frontier logo]()
$260
This Frontier deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/58:52 pm
ORD
- CLT
1 stop12h 04m
Frontier
Tue 8/1112:01 pm
CLT
- ORD
1 stop9h 14m
Frontier
Deal found 6/19![Frontier logo]()
$261
This Expedia deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:13 pm
ORD
- CLT
1 stop17h 16m
Frontier
Sat 7/188:28 pm
CLT
- ORD
1 stop27h 59m
Frontier
Deal found 6/21![Frontier logo]()
$263
This Super.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:30 am
DTW
- CHS
1 stop8h 53m
JetBlue
Tue 7/215:19 pm
CHS
- DTW
1 stop5h 26m
JetBlue
Deal found 6/18![JetBlue logo]()
$215
This Frontier deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/159:28 am
ORD
- CLT
1 stop8h 14m
Frontier
Sat 7/1812:24 pm
CLT
- ORD
1 stop11h 46m
Frontier
Deal found 6/20![Frontier logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/159:12 am
DTW
- SAV
1 stop8h 43m
Multiple Airlines
Wed 7/2912:19 pm
SAV
- DTW
1 stop24h 36m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/189:12 am
DTW
- SAV
1 stop8h 43m
Multiple Airlines
Sat 7/2512:19 pm
SAV
- DTW
1 stop24h 36m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$244
This Super.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:30 am
DTW
- CHS
1 stop9h 10m
JetBlue
Thu 7/235:19 pm
CHS
- DTW
1 stop5h 26m
JetBlue
Deal found 6/17![JetBlue logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/299:12 am
DTW
- SAV
1 stop8h 43m
Multiple Airlines
Sat 8/112:19 pm
SAV
- DTW
1 stop24h 36m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:13 pm
DTW
- SAV
2 stops25h 02m
Multiple Airlines
Wed 8/512:19 pm
SAV
- DTW
1 stop24h 36m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/299:12 am
DTW
- SAV
1 stop8h 43m
Multiple Airlines
Sun 8/210:05 am
SAV
- DTW
1 stop26h 50m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:50 pm
ORD
- CLT
2 stops26h 22m
Frontier
Mon 8/36:41 pm
CLT
- ORD
1 stop18h 34m
Frontier
Deal found 6/17![Frontier logo]()
$262
One-way flights from Michigan to South CarolinaSearch for one-way flight options from Michigan to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 21, 2026.
Search for one-way flight options from Michigan to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1911:00 am
DTW
- CLT
1 stop8h 55m
Frontier
Deal found 6/21![Frontier logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:18 am
DTW
- CLT
1 stop28h 02m
Frontier
Deal found 6/20![Frontier logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:00 am
DTW
- SAV
1 stop26h 00m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:00 am
DTW
- CLT
1 stop8h 55m
Frontier
Deal found 6/17![Frontier logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:08 am
DTW
- CLT
1 stop11h 05m
Frontier
Deal found 6/17![Frontier logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:05 am
ORD
- SAV
1 stop8h 50m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/19:12 am
DTW
- CLT
1 stop11h 55m
Frontier
Deal found 6/18![Frontier logo]()
$98
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:00 am
ORD
- MYR
Nonstop2h 19m
United Airlines
Deal found 6/16![United Airlines logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:08 am
DTW
- CLT
1 stop11h 05m
Frontier
Deal found 6/18![Frontier logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:18 am
DTW
- CHS
1 stop7h 56m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:05 am
ORD
- GSP
1 stop22h 52m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:08 am
DTW
- CLT
1 stop11h 05m
Frontier
Deal found 6/18![Frontier logo]()
$102
Find flight deals from Michigan to South Carolina
Keep the following information in mind while searching for Michigan to South Carolina flight deals. Data was last updated June 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $211 (Kiwi.com) |
One-way from | $84 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $409 |
Good round-trip deal | $95 or less |
Good one-way deal | $218 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
Use the filters below to find and compare flights from Michigan to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Wed 8/19
10:54 am-4:12 pm
1 stop4h 18m
Charlotte Douglas
Tue 8/25
6:45 am-11:51 am
1 stop6h 06m
$267
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Sat 8/22
7:00 am-12:17 pm
1 stop4h 17m
Charlotte Douglas
Sat 8/29
1:17 pm-4:17 pm
1 stop4h 00m
$267
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Tue 8/25
10:25 am-1:32 pm
Nonstop2h 07m
Greenville
Sat 8/29
2:18 pm-3:30 pm
Nonstop2h 12m
$269
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Wed 8/19
12:35 pm-7:00 pm
2 stops5h 25m
Charlotte Douglas
Tue 8/25
1:30 pm-6:45 pm
1 stop6h 15m
$272
ChicagoMyrtle Beach
ORD - MYR
ORDMYR
Chicago O'Hare Intl
Wed 8/12
11:27 am-2:53 pm
Nonstop2h 26m
Myrtle Beach Intl
Wed 8/19
10:23 am-4:59 pm
1 stop7h 36m
$276
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Sat 9/19
9:29 am-4:06 pm
1 stop5h 37m
Charlotte Douglas
Mon 9/28
9:42 am-12:39 pm
1 stop3h 57m
$278
ChicagoMyrtle Beach
ORD - MYR
ORDMYR
Chicago O'Hare Intl
Tue 7/28
11:00 am-2:19 pm
Nonstop2h 19m
Myrtle Beach Intl
Tue 8/4
10:34 am-5:02 pm
1 stop7h 28m
$287
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Wed 7/29
2:07 pm-9:47 pm
1 stop6h 40m
Greenville
Mon 8/3
1:28 pm-4:51 pm
1 stop4h 23m
$289
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Fri 8/21
5:30 am-10:40 am
1 stop4h 10m
Greenville
Sun 8/23
11:10 am-4:17 pm
1 stop6h 07m
$289
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Fri 7/24
6:35 am-2:01 pm
1 stop6h 26m
Greenville
Sun 7/26
7:10 am-1:03 pm
1 stop6h 53m
$289
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Michigan to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Michigan with our price prediction graph.
MDW-CLT
ORD-GSP
DTW-CHS
ORD-CLT
ORD-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to South Carolina
USMI-USSC
MDW-CLT
ORD-GSP
DTW-CHS
ORD-CLT
What is the cheapest month to book a flight from Michigan to South Carolina?
Currently, June is the cheapest month in which you can book a flight from Michigan to South Carolina (average of $49). Flying from Michigan to South Carolina in August is currently the most expensive (average of $458). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to SC?
Find hourly flight availability from Michigan to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 21, 2026.
When flying from Michigan to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 29% versus a flight in the afternoon.
Weekly flight availability from Michigan to South Carolina
Explore weekly flight availability from Michigan to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 21, 2026.
The most flights from USMI to USSC are scheduled on a Sunday (13 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (3 on average).
How much does it cost to fly round-trip from Michigan to South Carolina?
How far ahead should I book a flight from Michigan to South Carolina?
The price you pay for your flight from Michigan to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 33 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from Michigan to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Michigan to South Carolina. Price data was last updated on June 20, 2026.
Travelers seeking maximum savings on their Michigan to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 21, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Michigan to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from Michigan to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Michigan to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Michigan to South Carolina by cabin class
Find flights from Michigan to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Michigan and South Carolina flights
Browse other Michigan and South Carolina flight options. Last updated on June 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Michigan after your stay in South Carolina
Michigan to South Carolina flights
Consider these flights traveling from Michigan to South Carolina.
Top 5 airlines flying from Michigan to South Carolina
Discover the top 5 airlines that operate flights from Michigan to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$78 | Average$100 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$125 | Average$412 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$173 | Average$391 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$199 | Average$401 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$208 | Average$382 | FlexibilityNo cancel fee | On-time71% |