$87+ Cheap flights from Michigan to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/6. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — CHS
Nov 12 — Nov 191
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Michigan to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Michigan to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Michigan to South CarolinaExplore the most affordable flight options available from Michigan to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2026.
Explore the most affordable flight options available from Michigan to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:53 pm -
1 stop17h 45m
Sat 12/56:40 am -
1 stop16h 45m
Deal found 10/11![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:29 pm -
1 stop16h 44m
Tue 11/174:03 pm -
1 stop7h 34m
Deal found 10/8![Multiple Airlines logo]()
$222
This JetBlue deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:46 am -
1 stop7h 28m
Thu 11/124:05 pm -
1 stop6h 29m
Deal found 10/8![JetBlue logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:19 pm -
1 stop18h 10m
Mon 11/168:52 pm -
2 stops26h 45m
Deal found 10/11![Multiple Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:02 pm -
1 stop14h 36m
Tue 11/173:00 pm -
2 stops26h 59m
Deal found 10/8![Multiple Airlines logo]()
$226
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:50 am -
2 stops9h 35m
Tue 11/173:25 pm -
1 stop6h 45m
Deal found 10/8![Southwest logo]()
$229
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:30 am -
1 stop4h 50m
Tue 11/178:00 am -
2 stops10h 00m
Deal found 10/8![Southwest logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:29 pm -
1 stop26h 45m
Tue 11/103:00 pm -
1 stop20h 40m
Deal found 10/9![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:07 pm -
1 stop11h 31m
Thu 11/129:39 pm -
1 stop22h 45m
Deal found 10/11![Multiple Airlines logo]()
$236
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:50 pm -
Nonstop2h 12m
Sat 12/56:47 pm -
Nonstop2h 13m
Deal found 10/12![Delta logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:07 pm -
1 stop11h 31m
Wed 11/187:54 pm -
1 stop27h 43m
Deal found 10/8![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:07 pm -
1 stop11h 31m
Mon 11/164:57 pm -
1 stop6h 40m
Deal found 10/10![Multiple Airlines logo]()
$243
Best flights from Michigan to South CarolinaDiscover carefully curated flight deals from Michigan to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 13, 2026.
Discover carefully curated flight deals from Michigan to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 13, 2026.
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:35 am -
2 stops12h 25m
Wed 10/288:40 am -
1 stop4h 15m
Deal found 10/8![Southwest logo]()
$254
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop4h 51m
Sat 11/147:02 am -
1 stop6h 47m
Deal found 10/8![American Airlines logo]()
$257
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:00 am -
2 stops10h 11m
Wed 11/411:27 am -
2 stops10h 37m
Deal found 10/8![United Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:00 pm -
Nonstop2h 08m
Mon 11/166:53 pm -
Nonstop2h 07m
Deal found 10/13![Delta logo]()
$279
This JetBlue deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:46 am -
1 stop7h 28m
Mon 11/164:05 pm -
1 stop6h 29m
Deal found 10/8![JetBlue logo]()
$281
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:35 am -
1 stop5h 36m
Wed 11/1111:27 am -
1 stop7h 01m
Deal found 10/8![United Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:30 pm -
1 stop6h 37m
Mon 12/146:47 pm -
Nonstop2h 13m
Deal found 10/12![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:25 pm -
2 stops7h 35m
Wed 12/21:25 pm -
2 stops9h 05m
Deal found 10/8![Southwest logo]()
$302
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/34:56 pm -
1 stop6h 48m
Sun 2/76:00 am -
2 stops10h 26m
Deal found 10/11![American Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:40 am -
Nonstop2h 00m
Sun 11/226:51 pm -
1 stop6h 06m
Deal found 10/9![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:55 am -
2 stops10h 20m
Tue 11/108:05 am -
2 stops10h 35m
Deal found 10/8![Southwest logo]()
$302
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/38:30 am -
1 stop5h 16m
Mon 2/84:58 pm -
1 stop5h 20m
Deal found 10/13![United Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:45 am -
Nonstop1h 57m
Tue 11/1011:30 am -
Nonstop2h 00m
Deal found 10/13![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:55 am -
2 stops12h 15m
Sat 11/149:45 am -
2 stops10h 30m
Deal found 10/8![Southwest logo]()
$308
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/225:03 am -
1 stop4h 58m
Sun 1/247:07 am -
1 stop7h 40m
Deal found 10/8![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:34 pm -
2 stops8h 13m
Wed 11/1810:42 am -
1 stop4h 11m
Deal found 10/12![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/272:45 pm -
1 stop6h 28m
Wed 12/212:55 pm -
1 stop4h 13m
Deal found 10/12![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1511:00 am -
1 stop5h 30m
Fri 12/187:55 pm -
1 stop4h 30m
Deal found 10/9![Southwest logo]()
$309
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:46 pm -
1 stop6h 06m
Mon 11/96:42 pm -
1 stop5h 59m
Deal found 10/10![American Airlines logo]()
$345
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am -
2 stops7h 28m
Sat 11/147:00 am -
2 stops7h 53m
Deal found 10/10![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:43 pm -
1 stop4h 36m
Sat 11/147:00 am -
1 stop5h 38m
Deal found 10/12![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:30 am -
1 stop4h 50m
Tue 1/57:30 am -
2 stops11h 10m
Deal found 10/12![Southwest logo]()
$314
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/35:25 am -
2 stops8h 41m
Sat 2/62:42 pm -
2 stops7h 39m
Deal found 10/11![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:00 am -
1 stop4h 44m
Sat 11/141:55 pm -
1 stop7h 39m
Deal found 10/11![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/74:29 pm -
1 stop5h 31m
Sat 11/142:52 pm -
2 stops7h 34m
Deal found 10/9![United Airlines logo]()
$320
This Southwest deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:35 am -
2 stops8h 35m
Thu 11/192:50 pm -
1 stop7h 40m
Deal found 10/12![Southwest logo]()
$320
This Delta deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:25 am -
1 stop6h 41m
Mon 11/236:53 pm -
Nonstop2h 07m
Deal found 10/9![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:15 am -
1 stop6h 53m
Mon 11/235:47 pm -
1 stop4h 55m
Deal found 10/8![American Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:43 am -
1 stop4h 10m
Sun 11/225:47 pm -
1 stop6h 47m
Deal found 10/12![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:25 am -
1 stop6h 49m
Mon 11/93:47 pm -
1 stop6h 29m
Deal found 10/8![Delta logo]()
$339
Last-minute flights from Michigan to South CarolinaDiscover last-minute flight deals from Michigan to South Carolina. Data last updated October 13, 2026 and is based on user searches.
Discover last-minute flight deals from Michigan to South Carolina. Data last updated October 13, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:35 pm -
1 stop17h 03m
Thu 11/126:45 am -
2 stops29h 22m
Deal found 10/9![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:29 pm -
1 stop26h 45m
Tue 11/103:00 pm -
1 stop20h 40m
Deal found 10/9![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:19 pm -
1 stop18h 10m
Mon 11/168:52 pm -
2 stops26h 45m
Deal found 10/11![Multiple Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:07 pm -
1 stop11h 31m
Thu 11/129:39 pm -
1 stop22h 45m
Deal found 10/11![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:07 pm -
1 stop11h 31m
Wed 11/187:54 pm -
1 stop27h 43m
Deal found 10/8![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:07 pm -
1 stop11h 31m
Mon 11/164:57 pm -
1 stop6h 40m
Deal found 10/10![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:29 pm -
1 stop16h 44m
Tue 11/174:03 pm -
1 stop7h 34m
Deal found 10/8![Multiple Airlines logo]()
$222
This JetBlue deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:46 am -
1 stop7h 28m
Thu 11/124:05 pm -
1 stop6h 29m
Deal found 10/8![JetBlue logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:02 pm -
1 stop14h 36m
Tue 11/173:00 pm -
2 stops26h 59m
Deal found 10/8![Multiple Airlines logo]()
$226
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:50 am -
2 stops9h 35m
Tue 11/173:25 pm -
1 stop6h 45m
Deal found 10/8![Southwest logo]()
$229
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:30 am -
1 stop4h 50m
Tue 11/178:00 am -
2 stops10h 00m
Deal found 10/8![Southwest logo]()
$229
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:00 pm -
Nonstop2h 08m
Tue 11/171:06 pm -
Nonstop2h 14m
Deal found 10/12![Delta logo]()
$239
One-way flights from Michigan to South CarolinaSearch for one-way flight options from Michigan to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 13, 2026.
Search for one-way flight options from Michigan to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/610:08 am -
1 stop22h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Multiple Airlines logo]()
$87
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/116:00 am -
1 stop26h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Multiple Airlines logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:01 pm -
2 stops36h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Multiple Airlines logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/147:33 pm -
1 stop13h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![Multiple Airlines logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:37 pm -
2 stops36h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Multiple Airlines logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/95:52 pm -
2 stops13h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Multiple Airlines logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/76:00 am -
1 stop25h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Multiple Airlines logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/83:08 pm -
1 stop17h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Multiple Airlines logo]()
$110
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:00 am -
1 stop7h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Southwest logo]()
$112
This JetBlue deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:36 am -
1 stop5h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![JetBlue logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:07 pm -
1 stop11h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:29 pm -
1 stop15h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![Multiple Airlines logo]()
$114
Find flight deals from Michigan to South Carolina
Keep the following information in mind while searching for Michigan to South Carolina flight deals. Data was last updated October 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $215 (Kiwi.com) |
One-way from | $87 (Kiwi.com) |
Popular in | March |
Cheapest in | November |
Average price | $408 |
Good round-trip deal | $389 or less |
Good one-way deal | $243 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 13, 2026.
Use the filters below to find and compare flights from Michigan to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitCharleston
DTW Detroit Metropolitan Wayne County - CHS Charleston
DTWCHS
Detroit Metropolitan Wayne County
Wed 12/9
6:36 am-11:53 am
1 stop5h 17m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$112
DetroitCharleston
DTW Detroit Metropolitan Wayne County - CHS Charleston
DTWCHS
Detroit Metropolitan Wayne County
Sat 12/12
6:36 am-11:53 am
1 stop5h 17m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$112
Grand RapidsGreenville
GRR Grand Rapids Gerald R. Ford Intl - GSP Greenville
GRRGSP
Grand Rapids Gerald R. Ford Intl
Sat 11/7
5:50 am-11:07 am
1 stop5h 17m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
Grand RapidsCharleston
GRR Grand Rapids Gerald R. Ford Intl - CHS Charleston
GRRCHS
Grand Rapids Gerald R. Ford Intl
Sat 11/7
8:40 am-7:12 pm
2 stops10h 32m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$134
Grand RapidsCharleston
GRR Grand Rapids Gerald R. Ford Intl - CHS Charleston
GRRCHS
Grand Rapids Gerald R. Ford Intl
Sat 12/12
6:35 am-1:15 pm
2 stops6h 40m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$134
Grand RapidsGreenville
GRR Grand Rapids Gerald R. Ford Intl - GSP Greenville
GRRGSP
Grand Rapids Gerald R. Ford Intl
Sat 11/7
7:00 am-7:01 pm
2 stops12h 01m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$134
DetroitMyrtle Beach
DTW Detroit Metropolitan Wayne County - MYR Myrtle Beach Intl
DTWMYR
Detroit Metropolitan Wayne County
Sat 12/12
5:30 am-9:55 am
1 stop4h 25m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
DetroitCharleston
DTW Detroit Metropolitan Wayne County - CHS Charleston
DTWCHS
Detroit Metropolitan Wayne County
Fri 12/11
6:36 am-11:53 am
1 stop5h 17m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$142
DetroitCharleston
DTW Detroit Metropolitan Wayne County - CHS Charleston
DTWCHS
Detroit Metropolitan Wayne County
Mon 11/2
7:46 am-3:15 pm
1 stop7h 29m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$148
Grand RapidsMyrtle Beach
GRR Grand Rapids Gerald R. Ford Intl - MYR Myrtle Beach Intl
GRRMYR
Grand Rapids Gerald R. Ford Intl
Mon 11/2
7:15 am-9:55 am
1 stop26h 40m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$150
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Michigan to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Michigan with our price prediction graph.
DTW-CHS
DTW-GSP
DTW-MYR
GRR-MYR
GRR-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to South Carolina
USMI-USSC
DTW-CHS
DTW-GSP
DTW-MYR
GRR-MYR
What is the cheapest month to book a flight from Michigan to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Michigan to South Carolina (average of $342). Flying from Michigan to South Carolina in March is currently the most expensive (average of $447). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to SC?
Find hourly flight availability from Michigan to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 13, 2026.
When flying from Michigan to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 30% versus a flight in the afternoon.
Weekly flight availability from Michigan to South Carolina
Explore weekly flight availability from Michigan to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated October 13, 2026.
The most flights from USMI to USSC are scheduled on a Monday (13 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (3 on average).
How much does it cost to fly round-trip from Michigan to South Carolina?
Airfare is below average for this route at the moment.
Michigan to South Carolina flights typically cost between $388 and $549 in December.The cheapest round-trip price found within the last 5 days was $215 on Multiple Airlines (Dec 2-Dec 5).
How far ahead should I book a flight from Michigan to South Carolina?
The price you pay for your flight from Michigan to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 86 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from Michigan to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Michigan to South Carolina. Price data was last updated on October 10, 2026.
Travelers seeking maximum savings on their Michigan to South Carolina flight should consider departing on Sunday mornings when fares are most often at their lowest. Thursday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 13, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Michigan to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
7.9
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
7.9
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
7.9
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
7.9
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
7.9
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
7.9
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Michigan to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for Michigan to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Michigan to South Carolina by cabin class
Find flights from Michigan to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Michigan and South Carolina flights
Browse other Michigan and South Carolina flight options. Last updated on October 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Michigan after your stay in South Carolina
Michigan to South Carolina flights
Consider these flights traveling from Michigan to South Carolina.
Top 5 airlines flying from Michigan to South Carolina
Discover the top 5 airlines that operate flights from Michigan to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$80 | Average$115 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$172 | Average$413 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$188 | Average$437 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$235 | Average$405 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$238 | Average$401 | FlexibilityNo cancel fee | On-time71% |