South Carolina

$54+ Cheap flights from Michigan to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/16. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — CHS
Apr 5 — Apr 121
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Cheap flight deals from Michigan to South Carolina

Cheapest flights from Michigan to South Carolina
Explore the most affordable flight options available from Michigan to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 6, 2026.

This Super.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/237:11 pm
ORD
-
CLT
Nonstop2h 02m
Frontier
Mon 3/3010:52 pm
CLT
-
ORD
Nonstop2h 31m
Frontier
Deal found 3/2$97
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:01 pm
ORD
-
CLT
1 stop4h 52m
Multiple Airlines
Mon 3/3010:52 pm
CLT
-
ORD
Nonstop2h 31m
Multiple Airlines
Deal found 3/1$99
This Frontier deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:02 pm
ORD
-
CLT
Nonstop2h 10m
Frontier
Sat 4/117:09 pm
CLT
-
ORD
Nonstop2h 30m
Frontier
Deal found 3/3$100
This Expedia deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/122:09 pm
ORD
-
CLT
1 stop6h 52m
Multiple Airlines
Fri 5/159:26 pm
CLT
-
ORD
Nonstop2h 27m
Multiple Airlines
Deal found 3/2$102
This Super.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/201:12 pm
ORD
-
CLT
Nonstop2h 10m
Frontier
Thu 4/234:19 pm
CLT
-
ORD
Nonstop2h 34m
Frontier
Deal found 3/1$103
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:22 pm
ORD
-
CLT
Nonstop2h 17m
Frontier
Mon 4/205:17 pm
CLT
-
ORD
Nonstop2h 33m
Frontier
Deal found 3/5$104
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:53 pm
ORD
-
CLT
1 stop9h 51m
Multiple Airlines
Fri 5/159:26 pm
CLT
-
ORD
Nonstop2h 27m
Multiple Airlines
Deal found 3/2$105
This Priceline deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:01 pm
ORD
-
CLT
1 stop4h 52m
Multiple Airlines
Fri 4/1010:43 pm
CLT
-
ORD
Nonstop2h 21m
Multiple Airlines
Deal found 3/5$106
This Frontier deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:00 pm
ORD
-
CLT
Nonstop2h 14m
Frontier
Sun 4/196:10 pm
CLT
-
ORD
Nonstop2h 31m
Frontier
Deal found 3/3$107
This Expedia deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:15 am
ORD
-
CLT
1 stop15h 13m
Frontier
Sun 5/34:41 pm
CLT
-
ORD
Nonstop2h 34m
Frontier
Deal found 3/4$108
This Expedia deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:01 pm
ORD
-
CLT
1 stop4h 52m
Multiple Airlines
Thu 4/1610:24 pm
CLT
-
ORD
Nonstop2h 20m
Multiple Airlines
Deal found 3/3$109
This Super.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:00 pm
ORD
-
CLT
Nonstop2h 14m
Frontier
Mon 4/139:40 pm
CLT
-
ORD
Nonstop2h 27m
Frontier
Deal found 3/3$111

Find flight deals from Michigan to South Carolina

Keep the following information in mind while searching for Michigan to South Carolina flight deals. Data was last updated March 6, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$97
(Super.com)

One-way from

$54
(Frontier)

Popular in

January

Cheapest in

August

Average price

$289

Good round-trip deal

$368 or less

Good one-way deal

$209 or less
Provider with most accurate pricing for Detroit (DTT)-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Detroit (DTT)-Myrtle Beach Intl flights.
From Michigan to South Carolina
One-way flight from Michigan to South Carolina
Highest demand for flights based on searches. 29% potential increase in price ($116 potential increase over avg. RT price).
Cheapest flight prices on average. 7% potential price decrease ($20 potential savings vs. average RT price).
Average for round-trip flights in March 2026
Price to beat on a round-trip flight from Michigan to South Carolina.
Price to beat on a one-way flight from Michigan to South Carolina.

Cheapflights Fare Finder

 
Customize your flight search to find flights from Michigan to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 6, 2026.
Use the filters below to find and compare flights from Michigan to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Wed 4/22

7:19 am-9:09 am

Nonstop1h 50m

Charlotte Douglas

Wed 4/29

9:36 am-11:30 am

Nonstop1h 54m

$179

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Mon 4/27

5:15 am-11:11 am

1 stop4h 56m

Charlotte Douglas

Sat 5/2

6:00 am-10:19 am

1 stop5h 19m

$187
Quickest round-trip

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Sat 5/2

10:15 am-12:03 pm

Nonstop1h 48m

Charlotte Douglas

Tue 5/5

6:00 am-7:44 am

Nonstop1h 44m

$199

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 3/25

7:05 am-10:01 am

Nonstop1h 56m

Greenville

Sun 3/29

6:30 am-7:54 am

Nonstop2h 24m

$209

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 4/2

2:32 pm-9:52 pm

1 stop6h 20m

Greenville

Thu 4/9

7:59 pm-11:54 pm

1 stop4h 55m

$213

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 4/9

5:45 pm-8:57 pm

Nonstop2h 12m

Charlotte Douglas

Sun 4/12

6:15 am-7:43 am

Nonstop2h 28m

$217

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Wed 5/6

12:50 pm-8:45 pm

2 stops6h 55m

Charlotte Douglas

Wed 5/13

1:45 pm-10:15 pm

2 stops9h 30m

$227

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 6/4

7:07 am-12:05 pm

1 stop3h 58m

Greenville

Sun 6/7

7:15 am-12:39 pm

1 stop6h 24m

$228

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 6/4

6:30 am-2:20 pm

1 stop6h 50m

Greenville

Sun 6/7

6:00 am-7:20 am

Nonstop2h 20m

$233

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Tue 4/21

5:45 pm-8:47 pm

Nonstop2h 02m

Greenville

Tue 4/28

10:33 am-2:27 pm

1 stop4h 54m

$239

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/5

Showing 1-10 of 60 resultsSorted by cheapest first
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6

Best time to book a flight from Michigan to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Michigan with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Michigan to South Carolina

What is the cheapest month to book a flight from Michigan to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Michigan to South Carolina (average of $78). Flying from Michigan to South Carolina in January is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MI to SC?

Find hourly flight availability from Michigan to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 6, 2026.

When flying from Michigan to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 32% versus a flight at noon.

What is the cheapest day to fly from Michigan to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Michigan to South Carolina. Price data was last updated on February 21, 2026.

Travelers seeking maximum savings on their Michigan to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 6, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Michigan to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Related info for your journey

Find useful and relevant information for your journey from Michigan to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Michigan to South Carolina?

    A quick flight from Michigan to South Carolina can take about 1h 50m. Delta provides one of the quickest options available for as low as $179. Airlines will cover a distance of 500 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Michigan to South Carolina one-way?

    The cheapest airlines for a one-way flight from Michigan to South Carolina are Spirit Airlines ($34), Allegiant Air ($44), and American Airlines ($99).

  • Can I find deals for flights from Michigan to South Carolina that include hotel bookings?

    Yes. In addition to deals on Michigan to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Michigan to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Michigan to South Carolina.

  • Can I find deals for business class flights from Michigan to South Carolina?

    Yes. Cheapflights offers flight deals from Michigan to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Michigan to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Michigan to South Carolina (average of $78). Flying from Michigan to South Carolina in January is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Michigan to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Michigan to South Carolina

Discover the top 6 airlines that operate flights from Michigan to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$64Average$159FlexibilityNo cancel feeOn-time65%
Allegiant AirCheapest$78Average$102FlexibilityNo cancel feeOn-time88%
DeltaCheapest$115Average$386FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$173Average$379FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$197Average$350FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$207Average$376FlexibilityNo cancel feeOn-time63%

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