$43+ Cheap flights from Michigan to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — CHS
May 2 — May 91
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Michigan to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Michigan to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Michigan to South CarolinaExplore the most affordable flight options available from Michigan to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2026.
Explore the most affordable flight options available from Michigan to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2026.
This CheapOair deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/301:27 pm
ORD
- CLT
1 stop23h 51m
Frontier
Sun 5/34:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/30![Frontier logo]()
$114
This Expedia deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:15 am
ORD
- CLT
1 stop15h 13m
Frontier
Mon 5/44:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/28![Frontier logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:16 pm
ORD
- CLT
Nonstop2h 15m
Frontier
Fri 4/244:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/28![Frontier logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:15 pm
ORD
- CLT
1 stop12h 55m
Multiple Airlines
Sun 5/34:41 pm
CLT
- ORD
Nonstop2h 34m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$119
This Super.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:15 am
ORD
- CLT
1 stop15h 13m
Frontier
Sun 5/34:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/30![Frontier logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 4/274:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/30![Frontier logo]()
$122
This Super.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Thu 4/304:19 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/30![Frontier logo]()
$123
This Expedia deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/49:06 am
ORD
- CLT
1 stop9h 42m
Multiple Airlines
Sun 5/34:41 pm
CLT
- ORD
Nonstop2h 34m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/412:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 5/115:58 pm
CLT
- ORD
1 stop30h 03m
Frontier
Deal found 3/30![Frontier logo]()
$127
This Priceline deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/192:00 pm
ORD
- CLT
Nonstop2h 16m
Frontier
Fri 5/14:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/1![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1612:45 pm
DTW
- CLT
1 stop4h 23m
Multiple Airlines
Mon 4/208:09 pm
CLT
- DTW
2 stops15h 29m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$147
This Cheapflightsfares deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:45 pm
DTW
- CLT
1 stop4h 23m
Spirit Airlines
Tue 4/287:12 am
CLT
- DTW
1 stop5h 40m
Spirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$149
Best flights from Michigan to South CarolinaDiscover carefully curated flight deals from Michigan to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 2, 2026.
Discover carefully curated flight deals from Michigan to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 2, 2026.
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:35 pm
ORD
- CLT
Nonstop2h 10m
United Airlines
Wed 5/66:15 am
CLT
- ORD
Nonstop2h 28m
United Airlines
Deal found 3/29![United Airlines logo]()
$237
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/107:00 am
ORD
- CLT
1 stop4h 14m
Delta
Tue 5/121:05 pm
CLT
- ORD
1 stop4h 24m
Delta
Deal found 3/30![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:55 am
ORD
- GSP
2 stops8h 45m
Southwest
Tue 4/286:45 am
GSP
- ORD
1 stop7h 05m
Southwest
Deal found 3/29![Southwest logo]()
$287
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:50 am
ORD
- GSP
Nonstop2h 04m
United Airlines
Tue 4/282:53 pm
GSP
- ORD
1 stop4h 51m
United Airlines
Deal found 3/29![United Airlines logo]()
$272
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/29:48 am
ORD
- GSP
1 stop5h 22m
Delta
Tue 7/77:10 am
GSP
- ORD
1 stop4h 27m
Delta
Deal found 4/1![Delta logo]()
$282
This Southwest deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:55 pm
ORD
- GSP
2 stops6h 40m
Southwest
Mon 5/116:25 am
GSP
- ORD
1 stop7h 25m
Southwest
Deal found 4/1![Southwest logo]()
$293
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:40 am
ORD
- GSP
Nonstop2h 03m
United Airlines
Tue 9/2210:25 am
GSP
- ORD
1 stop5h 11m
United Airlines
Deal found 4/1![United Airlines logo]()
$272
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/192:07 pm
ORD
- GSP
1 stop6h 41m
Delta
Sun 6/217:10 am
GSP
- ORD
1 stop4h 35m
Delta
Deal found 3/28![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:55 pm
ORD
- GSP
Nonstop2h 05m
United Airlines
Tue 8/46:00 am
GSP
- ORD
Nonstop2h 20m
United Airlines
Deal found 3/29![United Airlines logo]()
$277
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:00 pm
ORD
- GSP
1 stop6h 38m
Delta
Sun 5/177:20 am
GSP
- ORD
1 stop6h 41m
Delta
Deal found 3/28![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:40 am
MDW
- CHS
2 stops8h 50m
Southwest
Wed 4/292:25 pm
CHS
- MDW
2 stops6h 10m
Southwest
Deal found 4/1![Southwest logo]()
$321
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/189:00 am
ORD
- MYR
1 stop7h 09m
United Airlines
Mon 4/203:15 pm
MYR
- ORD
Nonstop2h 31m
United Airlines
Deal found 3/28![United Airlines logo]()
$281
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:15 am
ORD
- HHH
1 stop6h 05m
Delta
Sat 5/912:18 pm
HHH
- ORD
1 stop5h 37m
Delta
Deal found 3/29![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/81:00 pm
MDW
- CHS
2 stops7h 55m
Southwest
Wed 6/1010:45 am
CHS
- MDW
2 stops7h 10m
Southwest
Deal found 4/1![Southwest logo]()
$321
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:50 am
ORD
- GSP
Nonstop1h 57m
United Airlines
Thu 5/76:36 am
GSP
- ORD
Nonstop2h 24m
United Airlines
Deal found 4/1![United Airlines logo]()
$284
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:03 am
ORD
- HHH
1 stop6h 26m
Delta
Tue 7/2112:11 pm
HHH
- ORD
1 stop5h 33m
Delta
Deal found 3/29![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/23:30 pm
MDW
- CHS
Nonstop2h 05m
Southwest
Fri 5/87:40 am
CHS
- MDW
Nonstop2h 15m
Southwest
Deal found 3/30![Southwest logo]()
$327
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:10 am
ORD
- HHH
1 stop6h 23m
Delta
Tue 6/24:16 pm
HHH
- ORD
1 stop7h 20m
Delta
Deal found 3/28![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/251:00 pm
ORD
- SAV
1 stop5h 19m
United Airlines
Wed 4/295:45 am
SAV
- ORD
1 stop4h 53m
United Airlines
Deal found 3/28![United Airlines logo]()
$291
This Southwest deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/111:25 am
MDW
- CHS
2 stops8h 00m
Southwest
Sun 7/57:30 pm
CHS
- MDW
Nonstop2h 15m
Southwest
Deal found 3/31![Southwest logo]()
$328
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/319:25 pm
ORD
- CLT
Nonstop2h 20m
United Airlines
Tue 6/26:00 am
CLT
- ORD
1 stop4h 36m
United Airlines
Deal found 3/31![United Airlines logo]()
$301
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/232:00 pm
DTW
- CLT
Nonstop1h 50m
Delta
Tue 5/269:47 am
CLT
- DTW
Nonstop1h 58m
Delta
Deal found 4/2![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:15 am
MDW
- CHS
2 stops8h 25m
Southwest
Sat 6/62:30 pm
CHS
- MDW
2 stops7h 40m
Southwest
Deal found 4/1![Southwest logo]()
$343
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:45 am
ORD
- CHS
Nonstop2h 23m
United Airlines
Wed 6/103:08 pm
CHS
- ORD
Nonstop2h 46m
United Airlines
Deal found 4/2![United Airlines logo]()
$313
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:09 am
DTW
- CLT
Nonstop1h 46m
Delta
Wed 5/276:05 am
CLT
- DTW
Nonstop1h 46m
Delta
Deal found 3/28![Delta logo]()
$323
This Southwest deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/204:10 pm
DTW
- CHS
1 stop3h 50m
Southwest
Fri 5/221:15 pm
CHS
- DTW
1 stop6h 20m
Southwest
Deal found 4/1![Southwest logo]()
$359
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:12 pm
ORD
- CLT
Nonstop2h 12m
United Airlines
Sat 4/186:15 am
CLT
- ORD
Nonstop2h 18m
United Airlines
Deal found 4/1![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:19 am
DTW
- CLT
Nonstop1h 50m
Delta
Sat 5/25:11 pm
CLT
- DTW
Nonstop1h 51m
Delta
Deal found 4/1![Delta logo]()
$323
This Southwest deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2010:15 am
MDW
- CHS
1 stop3h 45m
Southwest
Sun 5/248:50 am
CHS
- MDW
Nonstop2h 15m
Southwest
Deal found 4/1![Southwest logo]()
$363
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:45 pm
DTW
- CLT
Nonstop1h 48m
Delta
Sat 5/166:05 am
CLT
- DTW
Nonstop1h 46m
Delta
Deal found 3/30![Delta logo]()
$323
Last-minute flights from Michigan to South CarolinaDiscover last-minute flight deals from Michigan to South Carolina. Data last updated April 2, 2026 and is based on user searches.
Discover last-minute flight deals from Michigan to South Carolina. Data last updated April 2, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/49:06 am
ORD
- CLT
1 stop9h 42m
Multiple Airlines
Sun 5/34:41 pm
CLT
- ORD
Nonstop2h 34m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1612:45 pm
DTW
- CLT
1 stop4h 23m
Multiple Airlines
Mon 4/208:09 pm
CLT
- DTW
2 stops15h 29m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:16 pm
ORD
- CLT
Nonstop2h 15m
Frontier
Fri 4/244:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/28![Frontier logo]()
$117
This Priceline deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/192:00 pm
ORD
- CLT
Nonstop2h 16m
Frontier
Fri 5/14:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/1![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 4/274:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/30![Frontier logo]()
$122
This Super.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Thu 4/304:19 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/30![Frontier logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:15 pm
ORD
- CLT
1 stop12h 55m
Multiple Airlines
Sun 5/34:41 pm
CLT
- ORD
Nonstop2h 34m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$119
This CheapOair deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/301:27 pm
ORD
- CLT
1 stop23h 51m
Frontier
Sun 5/34:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/30![Frontier logo]()
$114
This CheapOair deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/301:27 pm
ORD
- CLT
1 stop23h 51m
Frontier
Mon 5/44:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/31![Frontier logo]()
$125
This Expedia deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:15 am
ORD
- CLT
1 stop15h 13m
Frontier
Mon 5/44:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/28![Frontier logo]()
$115
This Super.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:15 am
ORD
- CLT
1 stop15h 13m
Frontier
Sun 5/34:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 3/30![Frontier logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/412:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 5/115:58 pm
CLT
- ORD
1 stop30h 03m
Frontier
Deal found 3/30![Frontier logo]()
$127
One-way flights from Michigan to South CarolinaSearch for one-way flight options from Michigan to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 2, 2026.
Search for one-way flight options from Michigan to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1612:45 pm
DTW
- CLT
1 stop4h 23m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$43
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:45 pm
DTW
- CLT
1 stop4h 23m
Spirit Airlines
Deal found 4/2![Spirit Airlines logo]()
$53
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:45 pm
DTW
- CLT
1 stop4h 23m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$60
This CheapOair deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:45 pm
DTW
- CLT
1 stop4h 23m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$61
This Super.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/251:27 pm
ORD
- CLT
1 stop7h 31m
Frontier
Deal found 4/1![Frontier logo]()
$69
This Frontier deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/21:27 pm
ORD
- CLT
1 stop7h 31m
Frontier
Deal found 4/1![Frontier logo]()
$70
This CheapOair deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:15 pm
ORD
- CLT
1 stop12h 55m
Spirit Airlines
Deal found 3/30![Spirit Airlines logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/289:16 am
DTW
- MYR
1 stop5h 28m
Spirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$73
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:26 am
DTW
- CLT
1 stop9h 11m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$74
This Super.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:00 pm
ORD
- CLT
Nonstop2h 14m
Frontier
Deal found 4/1![Frontier logo]()
$74
This Super.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:20 pm
DTW
- CLT
1 stop26h 15m
Frontier
Deal found 3/31![Frontier logo]()
$75
This Super.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:15 am
ORD
- CLT
1 stop15h 13m
Frontier
Deal found 3/31![Frontier logo]()
$75
Find flight deals from Michigan to South Carolina
Keep the following information in mind while searching for Michigan to South Carolina flight deals. Data was last updated April 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $114 (CheapOair) |
One-way from | $43 (Kiwi.com) |
Popular in | January |
Cheapest in | August |
Average price | $286 |
Good round-trip deal | $134 or less |
Good one-way deal | $50 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2026.
Use the filters below to find and compare flights from Michigan to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Mon 5/4
9:35 pm-12:45 am
Nonstop2h 10m
Charlotte Douglas
Wed 5/6
6:15 am-7:43 am
Nonstop2h 28m
$237
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Sun 5/10
7:00 am-12:14 pm
1 stop4h 14m
Charlotte Douglas
Tue 5/12
1:05 pm-4:29 pm
1 stop4h 24m
$257
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Wed 4/22
8:50 am-11:54 am
Nonstop2h 04m
Greenville
Tue 4/28
2:53 pm-6:44 pm
1 stop4h 51m
$272
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Fri 9/18
6:40 am-9:43 am
Nonstop2h 03m
Greenville
Tue 9/22
10:25 am-2:36 pm
1 stop5h 11m
$272
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Fri 7/31
1:55 pm-5:00 pm
Nonstop2h 05m
Greenville
Tue 8/4
6:00 am-7:20 am
Nonstop2h 20m
$277
ChicagoMyrtle Beach
ORD - MYR
ORDMYR
Chicago O'Hare Intl
Sat 4/18
9:00 am-5:09 pm
1 stop7h 09m
Myrtle Beach Intl
Mon 4/20
3:15 pm-4:46 pm
Nonstop2h 31m
$281
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Thu 7/2
9:48 am-4:10 pm
1 stop5h 22m
Greenville
Tue 7/7
7:10 am-10:37 am
1 stop4h 27m
$282
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Thu 4/30
6:50 am-9:47 am
Nonstop1h 57m
Greenville
Thu 5/7
6:36 am-8:00 am
Nonstop2h 24m
$284
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Wed 4/22
11:55 am-9:40 pm
2 stops8h 45m
Greenville
Tue 4/28
6:45 am-12:50 pm
1 stop7h 05m
$287
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Fri 6/19
2:07 pm-9:48 pm
1 stop6h 41m
Greenville
Sun 6/21
7:10 am-10:45 am
1 stop4h 35m
$289
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Michigan to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Michigan with our price prediction graph.
ORD-CLT
ORD-GSP
MDW-CHS
ORD-MYR
ORD-HHH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to South Carolina
USMI-USSC
ORD-CLT
ORD-GSP
MDW-CHS
ORD-MYR
What is the cheapest month to book a flight from Michigan to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Michigan to South Carolina (average of $78). Flying from Michigan to South Carolina in January is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to SC?
Find hourly flight availability from Michigan to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 2, 2026.
When flying from Michigan to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 25% versus a flight in the afternoon.
What is the cheapest day to fly from Michigan to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Michigan to South Carolina. Price data was last updated on March 28, 2026.
Travelers seeking maximum savings on their Michigan to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Michigan to South Carolina
Explore weekly flight availability from Michigan to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 2, 2026.
The most flights from USMI to USSC are scheduled on a Monday (8 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (2 on average).
How much does it cost to fly round-trip from Michigan to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 2, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Michigan to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Michigan to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for Michigan to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Michigan to South Carolina by cabin class
Find flights from Michigan to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Michigan and South Carolina flights
Browse other Michigan and South Carolina flight options. Last updated on April 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Michigan after your stay in South Carolina
Michigan to South Carolina flights
Consider these flights traveling from Michigan to South Carolina.
Top 6 airlines flying from Michigan to South Carolina
Discover the top 6 airlines that operate flights from Michigan to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$64 | Average$160 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$78 | Average$98 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$108 | Average$382 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$193 | Average$364 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$197 | Average$359 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$207 | Average$393 | FlexibilityNo cancel fee | On-time63% |