South Carolina

$260+ Cheap flights from McAllen (MFE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — CHS
May 30 — Jun 61
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Cheap flight deals from McAllen to South Carolina

Cheapest flights from McAllen to South Carolina
Explore the most affordable flight options available from McAllen to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:25 am
MFE
-
CLT
2 stops9h 25m
Delta
Wed 6/106:59 am
CLT
-
MFE
2 stops10h 24m
Delta
Deal found 4/26$319
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:25 am
MFE
-
CLT
2 stops12h 26m
Delta
Wed 6/38:01 am
CLT
-
MFE
2 stops9h 36m
Delta
Deal found 4/26$335
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:20 am
MFE
-
CLT
2 stops9h 58m
Delta
Sun 6/215:30 am
CLT
-
MFE
2 stops7h 25m
Delta
Deal found 4/29$349
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/610:39 am
MFE
-
CLT
1 stop8h 08m
American Airlines
Wed 6/106:04 pm
CLT
-
MFE
1 stop7h 17m
American Airlines
Deal found 4/26$359
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:59 pm
MFE
-
GSP
1 stop5h 56m
American Airlines
Fri 11/65:22 am
GSP
-
MFE
1 stop6h 22m
American Airlines
Deal found 4/29$399
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:25 pm
MFE
-
CLT
1 stop6h 28m
American Airlines
Wed 6/35:45 am
CLT
-
MFE
1 stop5h 14m
American Airlines
Deal found 4/26$401
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2212:07 pm
MFE
-
SAV
1 stop5h 13m
United Airlines
Wed 8/263:39 pm
SAV
-
MFE
1 stop7h 18m
United Airlines
Deal found 4/27$401
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:35 pm
MFE
-
GSP
2 stops6h 43m
Delta
Tue 7/285:16 pm
GSP
-
MFE
2 stops7h 43m
Delta
Deal found 4/29$403
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/212:47 pm
MFE
-
GSP
2 stops7h 34m
Delta
Fri 11/65:40 am
GSP
-
MFE
2 stops7h 47m
Delta
Deal found 4/29$409
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:37 am
MFE
-
GSP
1 stop7h 47m
American Airlines
Tue 7/285:27 pm
GSP
-
MFE
1 stop5h 19m
American Airlines
Deal found 4/29$417
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/299:38 am
MFE
-
SAV
1 stop7h 42m
United Airlines
Tue 9/19:50 am
SAV
-
MFE
2 stops13h 07m
United Airlines
Deal found 4/25$420
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:25 pm
MFE
-
CLT
1 stop6h 28m
American Airlines
Tue 5/265:45 am
CLT
-
MFE
1 stop5h 14m
American Airlines
Deal found 4/27$429

Find flight deals from McAllen to South Carolina

Keep the following information in mind while searching for McAllen to South Carolina flight deals. Data was last updated April 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$319
(Delta)

One-way from

$260
(American Airlines)
Provider with most accurate pricing for McAllen Miller Intl-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for McAllen Miller Intl-Myrtle Beach Intl flights.
From McAllen Miller Intl to South Carolina
One-way flight from McAllen Miller Intl to South Carolina

Cheapflights Fare Finder

 
Customize your flight search to find flights from McAllen to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from McAllen to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Sat 6/6

5:25 am-3:50 pm

2 stops9h 25m

Charlotte Douglas

Wed 6/10

6:59 am-4:23 pm

2 stops10h 24m

$319

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Sun 6/14

5:20 am-4:18 pm

2 stops9h 58m

Charlotte Douglas

Sun 6/21

5:30 am-11:55 am

2 stops7h 25m

$349

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Sat 6/6

10:39 am-7:47 pm

1 stop8h 08m

Charlotte Douglas

Wed 6/10

6:04 pm-12:21 am

1 stop7h 17m

$359

McAllenSavannah

MFE - SAV

MFESAV

McAllen Miller Intl

Sat 8/22

12:07 pm-6:20 pm

1 stop5h 13m

Savannah/Hilton Head

Wed 8/26

3:39 pm-9:57 pm

1 stop7h 18m

$401

McAllenSavannah

MFE - SAV

MFESAV

McAllen Miller Intl

Sat 8/29

12:07 pm-6:20 pm

1 stop5h 13m

Savannah/Hilton Head

Tue 9/1

3:39 pm-9:57 pm

1 stop7h 18m

$401

McAllenGreenville

MFE - GSP

MFEGSP

McAllen Miller Intl

Tue 7/21

10:37 am-7:24 pm

1 stop7h 47m

Greenville

Tue 7/28

5:27 pm-9:46 pm

1 stop5h 19m

$417
Quickest round-trip

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Fri 5/22

5:25 pm-12:53 am

1 stop6h 28m

Charlotte Douglas

Tue 5/26

5:45 am-9:59 am

1 stop5h 14m

$429

McAllenGreenville

MFE - GSP

MFEGSP

McAllen Miller Intl

Sat 8/22

5:00 am-9:17 pm

3 stops15h 17m

Greenville

Wed 8/26

7:00 am-3:59 pm

2 stops9h 59m

$479

McAllenGreenville

MFE - GSP

MFEGSP

McAllen Miller Intl

Thu 6/11

1:45 pm-10:56 pm

1 stop8h 11m

Greenville

Mon 6/15

7:55 pm-12:18 am

1 stop5h 23m

$495

McAllenGreenville

MFE - GSP

MFEGSP

McAllen Miller Intl

Fri 5/29

6:59 pm-9:49 pm

2 stops25h 50m

Greenville

Wed 6/3

10:30 am-9:51 pm

2 stops12h 21m

$549

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Best time to book a flight from McAllen to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from McAllen with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from McAllen to South Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 30, 2026.
See what other customers who have flown with Delta and American Airlines from McAllen to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Entertainment

7.8

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Entertainment

7.8

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Entertainment

7.8

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from McAllen to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from McAllen to South Carolina?

    Most people fly from McAllen Miller Intl (MFE) if they book a flight from McAllen to South Carolina. McAllen Miller Intl is conveniently located just 2.0 mi from McAllen’s city center.

  • How long is the flight from McAllen to South Carolina?

    A quick flight from McAllen to South Carolina can take about 5h 13m. Delta provides one of the quickest options available for as low as $401. Airlines will cover a distance of 1105 mi. This flight may include one or multiple stops.

  • What are the most popular routes from McAllen to South Carolina?

  • Can I find deals for flights from McAllen to South Carolina that include hotel bookings?

    Yes. In addition to deals on McAllen to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from McAllen to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from McAllen to South Carolina.

  • Can I find deals for business class flights from McAllen to South Carolina?

    Yes. Cheapflights offers flight deals from McAllen to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for McAllen to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from McAllen to South Carolina

Discover the top 2 airlines that operate flights from McAllen to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$158Average$459FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$234Average$445FlexibilityNo cancel feeOn-time71%

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