$210+ Cheap flights from South Carolina to McAllen (MFE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MFE
Nov 26 — Dec 31
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to McAllen with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to McAllen
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Cheapest flights from South Carolina to McAllenExplore the most affordable flight options available from South Carolina to McAllen. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.
Explore the most affordable flight options available from South Carolina to McAllen. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:18 pm -
1 stop5h 57m
Fri 11/134:21 pm -
1 stop5h 05m
Deal found 10/25![American Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:20 am -
2 stops7h 59m
Fri 11/135:20 am -
2 stops10h 09m
Deal found 10/25![Delta logo]()
$429
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:15 am -
2 stops10h 52m
Wed 12/95:00 am -
2 stops11h 09m
Deal found 10/23![United Airlines logo]()
$490
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:55 am -
2 stops10h 09m
Wed 11/115:00 am -
2 stops12h 04m
Deal found 10/23![United Airlines logo]()
$519
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:09 pm -
1 stop6h 20m
Sat 11/285:00 am -
1 stop6h 20m
Deal found 10/26![American Airlines logo]()
$549
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:10 pm -
1 stop8h 05m
Sat 11/75:08 am -
1 stop7h 12m
Deal found 10/22![American Airlines logo]()
$555
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:35 am -
2 stops7h 44m
Thu 11/265:20 am -
2 stops7h 05m
Deal found 10/22![Delta logo]()
$557
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:10 pm -
1 stop5h 58m
Thu 11/269:26 am -
1 stop6h 04m
Deal found 10/22![American Airlines logo]()
$570
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:40 am -
2 stops7h 26m
Sat 11/712:46 pm -
2 stops6h 24m
Deal found 10/22![Delta logo]()
$585
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:45 pm -
2 stops10h 30m
Wed 12/99:23 am -
1 stop6h 05m
Deal found 10/23![American Airlines logo]()
$588
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:10 pm -
1 stop8h 19m
Sun 11/224:19 pm -
1 stop6h 04m
Deal found 10/24![American Airlines logo]()
$609
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/203:40 pm -
1 stop8h 12m
Sat 1/25:39 am -
1 stop8h 10m
Deal found 10/25![American Airlines logo]()
$646
Best flights from South Carolina to McAllenDiscover carefully curated flight deals from South Carolina to McAllen that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.
Discover carefully curated flight deals from South Carolina to McAllen that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:18 pm -
1 stop5h 57m
Fri 11/134:21 pm -
1 stop5h 05m
Deal found 10/25![American Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:20 am -
2 stops7h 59m
Fri 11/135:20 am -
2 stops10h 09m
Deal found 10/25![Delta logo]()
$429
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:15 am -
2 stops10h 52m
Wed 12/95:00 am -
2 stops11h 09m
Deal found 10/23![United Airlines logo]()
$490
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:55 am -
2 stops10h 09m
Wed 11/115:00 am -
2 stops12h 04m
Deal found 10/23![United Airlines logo]()
$519
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:09 pm -
1 stop6h 20m
Sat 11/285:00 am -
1 stop6h 20m
Deal found 10/26![American Airlines logo]()
$549
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:35 am -
2 stops7h 44m
Thu 11/265:20 am -
2 stops7h 05m
Deal found 10/22![Delta logo]()
$557
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/191:46 pm -
1 stop6h 45m
Thu 11/266:00 am -
2 stops7h 01m
Deal found 10/22![American Airlines logo]()
$575
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:45 pm -
2 stops10h 30m
Wed 12/99:23 am -
1 stop6h 05m
Deal found 10/23![American Airlines logo]()
$588
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:12 pm -
1 stop5h 46m
Fri 11/135:15 pm -
1 stop20h 59m
Deal found 10/25![United Airlines logo]()
$703
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:10 pm -
1 stop8h 19m
Sun 11/224:19 pm -
1 stop6h 04m
Deal found 10/24![American Airlines logo]()
$609
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:40 am -
2 stops7h 39m
Fri 11/1312:59 pm -
2 stops8h 13m
Deal found 10/25![Delta logo]()
$796
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:16 am -
3 stops12h 42m
Thu 11/265:00 am -
2 stops8h 07m
Deal found 10/22![United Airlines logo]()
$922
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/205:15 am -
2 stops7h 56m
Sat 1/25:20 am -
2 stops8h 56m
Deal found 10/25![Delta logo]()
$923
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:35 am -
2 stops10h 59m
Sun 11/225:20 am -
2 stops6h 54m
Deal found 10/24![Delta logo]()
$996
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:30 am -
1 stop16h 26m
Sun 1/37:25 pm -
1 stop25h 24m
Deal found 10/24![United Airlines logo]()
$1,057
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2012:40 pm -
2 stops10h 16m
Sat 1/29:46 am -
2 stops8h 29m
Deal found 10/25![United Airlines logo]()
$1,410
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2012:22 pm -
2 stops10h 36m
Sun 11/227:00 am -
3 stops11h 08m
Deal found 10/24![United Airlines logo]()
$1,641
Last-minute flights from South Carolina to McAllenDiscover last-minute flight deals from South Carolina to McAllen. Data last updated October 27, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to McAllen. Data last updated October 27, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:10 pm -
1 stop8h 05m
Sat 11/75:08 am -
1 stop7h 12m
Deal found 10/22![American Airlines logo]()
$555
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:40 am -
2 stops7h 26m
Sat 11/712:46 pm -
2 stops6h 24m
Deal found 10/22![Delta logo]()
$585
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:55 am -
2 stops10h 09m
Wed 11/115:00 am -
2 stops12h 04m
Deal found 10/23![United Airlines logo]()
$519
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:18 pm -
1 stop5h 57m
Fri 11/134:21 pm -
1 stop5h 05m
Deal found 10/25![American Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:20 am -
2 stops7h 59m
Fri 11/135:20 am -
2 stops10h 09m
Deal found 10/25![Delta logo]()
$429
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:12 pm -
1 stop5h 46m
Fri 11/135:15 pm -
1 stop20h 59m
Deal found 10/25![United Airlines logo]()
$703
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:40 am -
2 stops7h 39m
Fri 11/1312:59 pm -
2 stops8h 13m
Deal found 10/25![Delta logo]()
$796
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:35 am -
2 stops7h 44m
Thu 11/265:20 am -
2 stops7h 05m
Deal found 10/22![Delta logo]()
$557
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:10 pm -
1 stop5h 58m
Thu 11/269:26 am -
1 stop6h 04m
Deal found 10/22![American Airlines logo]()
$570
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:16 am -
3 stops12h 42m
Thu 11/265:00 am -
2 stops8h 07m
Deal found 10/22![United Airlines logo]()
$922
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:10 pm -
1 stop8h 19m
Sun 11/224:19 pm -
1 stop6h 04m
Deal found 10/24![American Airlines logo]()
$609
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:09 pm -
1 stop6h 20m
Sat 11/285:00 am -
1 stop6h 20m
Deal found 10/26![American Airlines logo]()
$549
One-way flights from South Carolina to McAllenSearch for one-way flight options from South Carolina to McAllen. Find affordable one-way fares based on user searches. Data last updated October 27, 2026.
Search for one-way flight options from South Carolina to McAllen. Find affordable one-way fares based on user searches. Data last updated October 27, 2026.
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:18 pm -
1 stop5h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![American Airlines logo]()
$210
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:20 am -
2 stops7h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Delta logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:27 pm -
3 stops49h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$277
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:10 pm -
1 stop8h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![American Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:35 am -
2 stops10h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Delta logo]()
$545
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:49 am -
1 stop7h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![United Airlines logo]()
$681
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:35 pm -
2 stops9h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![American Airlines logo]()
$696
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:37 pm -
3 stops23h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![United Airlines logo]()
$828
Find flight deals from South Carolina to McAllen
Keep the following information in mind while searching for South Carolina to McAllen flight deals. Data was last updated October 27, 2026.
Most accurate provider | eDreams 2 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $419 (American Airlines) |
One-way from | $210 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to McAllen that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 27, 2026.
Use the filters below to find and compare flights from South Carolina to McAllen that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonMcAllen
CHS Charleston - MFE McAllen Miller Intl
CHSMFE
Charleston
Mon 11/9
5:20 am-12:19 pm
2 stops7h 59m
McAllen Miller Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$225
CharlestonMcAllen
CHS Charleston - MFE McAllen Miller Intl
CHSMFE
Charleston
Mon 11/9
3:27 pm-4:03 pm
3 stops49h 36m
McAllen Miller Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$277
CharlestonMcAllen
CHS Charleston - MFE McAllen Miller Intl
CHSMFE
Charleston
Mon 11/9
7:18 pm-12:15 am
1 stop5h 57m
McAllen Miller Intl
Fri 11/13
4:21 pm-10:26 pm
1 stop5h 05m
$419
CharlestonMcAllen
CHS Charleston - MFE McAllen Miller Intl
CHSMFE
Charleston
Mon 11/9
5:20 am-12:19 pm
2 stops7h 59m
McAllen Miller Intl
Fri 11/13
5:20 am-4:29 pm
2 stops10h 09m
$429
ColumbiaMcAllen
CAE Columbia Metropolitan - MFE McAllen Miller Intl
CAEMFE
Columbia Metropolitan
Fri 11/20
5:10 pm-12:29 am
1 stop8h 19m
McAllen Miller Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$447
ColumbiaMcAllen
CAE Columbia Metropolitan - MFE McAllen Miller Intl
CAEMFE
Columbia Metropolitan
Sat 12/5
6:15 am-4:07 pm
2 stops10h 52m
McAllen Miller Intl
Wed 12/9
5:00 am-5:09 pm
2 stops11h 09m
$490
CharlestonMcAllen
CHS Charleston - MFE McAllen Miller Intl
CHSMFE
Charleston
Sat 11/7
6:55 am-4:04 pm
2 stops10h 09m
McAllen Miller Intl
Wed 11/11
5:00 am-6:04 pm
2 stops12h 04m
$519
ColumbiaMcAllen
CAE Columbia Metropolitan - MFE McAllen Miller Intl
CAEMFE
Columbia Metropolitan
Fri 11/20
5:35 am-3:34 pm
2 stops10h 59m
McAllen Miller Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$545
CharlestonMcAllen
CHS Charleston - MFE McAllen Miller Intl
CHSMFE
Charleston
Sat 11/21
7:09 pm-12:29 am
1 stop6h 20m
McAllen Miller Intl
Sat 11/28
5:00 am-12:20 pm
1 stop6h 20m
$549
ColumbiaMcAllen
CAE Columbia Metropolitan - MFE McAllen Miller Intl
CAEMFE
Columbia Metropolitan
Thu 11/19
5:35 am-12:19 pm
2 stops7h 44m
McAllen Miller Intl
Thu 11/26
5:20 am-1:25 pm
2 stops7h 05m
$557
Showing 1-10 of 25 resultsSorted by cheapest first
Best time to book a flight from South Carolina to McAllen
Have a flexible travel schedule? Discover the best time to fly to McAllen from South Carolina with our price prediction graph.
CHS-MFE
CAE-MFE
GSP-MFE
Estimated round-trip price
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Everything you need to know about your flight from South Carolina to McAllen
USSC-MFE
CHS-MFE
CAE-MFE
GSP-MFE
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Related info for your journey
Find useful and relevant information for your journey from South Carolina to McAllen. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near McAllen?
Book flights to McAllen if you plan to visit one of these locationsPharr
Weslaco
Mission
Edinburg
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Alternative routes for South Carolina to McAllen
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Other flights to McAllen
Explore flights to McAllen departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 27, 2026.
South Carolina and McAllen flights
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South Carolina to McAllen flights
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Top airline flying from South Carolina to McAllen
Discover the top airline that operate flights from South Carolina to McAllen. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$309 | Average$486 | FlexibilityNo cancel fee | On-time71% |