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$161+ Cheap flights from McAllen (MFE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — CHS
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from McAllen to South Carolina

Cheapest flights from McAllen to South Carolina
Explore the most affordable flight options available from McAllen to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/183:48 pm
MFE
-
CLT
1 stop6h 01m
American Airlines
Wed 2/255:15 am
CLT
-
MFE
1 stop6h 00m
American Airlines
Deal found 1/19$279
This Delta deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:28 am
MFE
-
CLT
2 stops7h 11m
Delta
Wed 2/252:10 pm
CLT
-
MFE
2 stops10h 47m
Delta
Deal found 1/19$290
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/81:20 pm
MFE
-
SAV
2 stops6h 23m
Delta
Sun 4/125:33 am
SAV
-
MFE
2 stops8h 07m
Delta
Deal found 1/21$305
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/45:56 pm
MFE
-
CLT
1 stop5h 44m
American Airlines
Sun 2/87:28 am
CLT
-
MFE
1 stop8h 06m
American Airlines
Deal found 1/19$309
This Delta deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/45:25 am
MFE
-
CLT
2 stops9h 37m
Delta
Sun 2/85:25 am
CLT
-
MFE
2 stops7h 55m
Delta
Deal found 1/19$320
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/41:00 pm
MFE
-
SAV
2 stops9h 58m
Delta
Sun 2/85:30 am
SAV
-
MFE
2 stops7h 50m
Delta
Deal found 1/20$320
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/63:48 pm
MFE
-
CLT
1 stop7h 37m
American Airlines
Fri 3/135:15 am
CLT
-
MFE
1 stop6h 00m
American Airlines
Deal found 1/20$341
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/59:30 am
MFE
-
CLT
2 stops10h 46m
United Airlines
Mon 2/94:45 pm
CLT
-
MFE
1 stop6h 12m
United Airlines
Deal found 1/21$344
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:13 am
MFE
-
SAV
1 stop7h 05m
United Airlines
Wed 2/253:28 pm
SAV
-
MFE
1 stop7h 14m
United Airlines
Deal found 1/20$351
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/295:56 pm
MFE
-
CLT
1 stop5h 44m
American Airlines
Tue 2/35:23 am
CLT
-
MFE
1 stop6h 52m
American Airlines
Deal found 1/19$356
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/79:30 am
MFE
-
SAV
1 stop4h 40m
United Airlines
Tue 2/1011:43 am
SAV
-
MFE
1 stop5h 24m
United Airlines
Deal found 1/19$374
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/37:00 am
MFE
-
SAV
1 stop5h 17m
United Airlines
Sat 2/73:28 pm
SAV
-
MFE
1 stop5h 37m
United Airlines
Deal found 1/19$389

Find flight deals from McAllen to South Carolina

Keep the following information in mind while searching for McAllen to South Carolina flight deals. Data was last updated January 21, 2026.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$279
(American Airlines)

One-way from

$161
(American Airlines)
Provider with most accurate pricing for McAllen Miller Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for McAllen Miller Intl-Myrtle Beach Intl flights.
Search Deals
From McAllen Miller Intl to South Carolina
Search Deals
One-way flight from McAllen Miller Intl to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from McAllen to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from McAllen to South Carolina that are best for you.

Fly from

McAllen

Fly to

South Carolina

Route

Depart

Return

Price

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Wed 2/18

3:48 pm-10:49 pm

1 stop6h 01m

Charlotte Douglas

Wed 2/25

5:15 am-10:15 am

1 stop6h 00m

$279

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Wed 2/18

5:28 am-1:39 pm

2 stops7h 11m

Charlotte Douglas

Wed 2/25

2:10 pm-11:57 pm

2 stops10h 47m

$290

McAllenSavannah

MFE - SAV

MFESAV

McAllen Miller Intl

Wed 4/8

1:20 pm-8:43 pm

2 stops6h 23m

Savannah/Hilton Head

Sun 4/12

5:33 am-12:40 pm

2 stops8h 07m

$305

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Wed 2/4

5:56 pm-12:40 am

1 stop5h 44m

Charlotte Douglas

Sun 2/8

7:28 am-2:34 pm

1 stop8h 06m

$309

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Thu 2/5

5:25 am-1:38 pm

2 stops7h 13m

Charlotte Douglas

Mon 2/9

2:25 pm-11:57 pm

2 stops10h 32m

$320

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Wed 2/4

5:25 am-4:02 pm

2 stops9h 37m

Charlotte Douglas

Sun 2/8

5:25 am-12:20 pm

2 stops7h 55m

$320

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Thu 2/5

9:30 am-9:16 pm

2 stops10h 46m

Charlotte Douglas

Mon 2/9

4:45 pm-9:57 pm

1 stop6h 12m

$344

McAllenSavannah

MFE - SAV

MFESAV

McAllen Miller Intl

Sat 2/21

5:13 am-1:18 pm

1 stop7h 05m

Savannah/Hilton Head

Wed 2/25

9:40 am-9:42 pm

2 stops13h 02m

$356

McAllenSavannah

MFE - SAV

MFESAV

McAllen Miller Intl

Sat 2/7

7:00 am-3:10 pm

1 stop7h 10m

Savannah/Hilton Head

Tue 2/10

11:43 am-4:07 pm

1 stop5h 24m

$374

McAllenSavannah

MFE - SAV

MFESAV

McAllen Miller Intl

Tue 2/3

7:00 am-1:17 pm

1 stop5h 17m

Savannah/Hilton Head

Sat 2/7

3:28 pm-8:05 pm

1 stop5h 37m

$389

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Showing 1-10 of 29 results
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Best time to book a flight from McAllen to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from McAllen with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from McAllen to South Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 21, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from McAllen to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,089 reviews

Crew

8.5

Comfort

7.9

Boarding

8.1

Overall

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,089 reviews
Delta
7.9
Good
8,089 reviews

Crew

8.5

Comfort

7.9

Boarding

8.1

Overall

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,191 reviews
Delta
7.9
Good
8,089 reviews

Crew

8.5

Comfort

7.9

Boarding

8.1

Overall

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,174 reviews
Delta
7.9
Good
8,089 reviews

Crew

8.5

Comfort

7.9

Boarding

8.1

Overall

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from McAllen to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from McAllen to South Carolina?

    Most people fly from McAllen Miller Intl (MFE) if they book a flight from McAllen to South Carolina. McAllen Miller Intl is conveniently located just 2.0 mi from McAllen’s city center.

  • How long is the flight from McAllen to South Carolina?

    A quick flight from McAllen to South Carolina can take about 6h 01m. American Airlines provides one of the quickest options available for as low as $279. Airlines will cover a distance of 1199 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from McAllen to South Carolina one-way?

    $39 is the cheapest one-way deal found within the past few days, from Volaris. You may also be able to find cheap deals on Aeromexico and United Airlines, with prices starting from $133 and $229, respectively.

  • What are the most popular routes from McAllen to South Carolina?

    Most travelers choose McAllen Miller Intl - Savannah/Hilton Head, McAllen Miller Intl - Charlotte Douglas or McAllen Miller Intl - Columbia Metropolitan when deciding on the best route from McAllen to South Carolina.

  • Can I find deals for flights from McAllen to South Carolina that include hotel bookings?

    Yes. In addition to deals on McAllen to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from McAllen to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from McAllen to South Carolina.

  • Can I find deals for business class flights from McAllen to South Carolina?

    Yes. Cheapflights offers flight deals from McAllen to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for McAllen to South Carolina

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Top 3 airlines flying from McAllen to South Carolina

Discover the top 3 airlines that operate flights from McAllen to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$158Average$459FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$234Average$385FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$475Average$475FlexibilityNo cancel feeOn-time69%

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