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South Carolina

$154+ Cheap flights from McAllen (MFE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/4. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — CHS
Nov 9 — Nov 161
Sun 11/9
Sun 11/16
1 adult, Economy
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Find flight deals from McAllen to South Carolina

Cheapest flights from McAllen to South Carolina
Explore the most affordable flight options available from McAllen to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 10, 2025.

This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:10 pmMFE - CLT
1 stop6h 17mAmerican Airlines
Tue 11/184:36 pmCLT - MFE
1 stop7h 43mAmerican Airlines
Deal found 10/8$259
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:25 amMFE - CLT
2 stops9h 30mDelta
Tue 11/185:30 amCLT - MFE
2 stops7h 34mDelta
Deal found 10/8$269
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:27 amMFE - CLT
1 stop5h 50mAmerican Airlines
Sun 10/265:37 amCLT - MFE
1 stop5h 14mAmerican Airlines
Deal found 10/8$289
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2512:31 pmMFE - CLT
2 stops10h 19mDelta
Tue 10/285:30 amCLT - MFE
2 stops7h 21mDelta
Deal found 10/8$299
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/247:00 amMFE - CLT
1 stop7h 53mUnited Airlines
Tue 10/284:48 pmCLT - MFE
1 stop6h 11mUnited Airlines
Deal found 10/9$319
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:10 pmMFE - CLT
1 stop6h 17mAmerican Airlines
Sat 11/221:25 pmCLT - MFE
1 stop6h 15mAmerican Airlines
Deal found 10/7$368
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:25 amMFE - CLT
2 stops10h 15mDelta
Tue 11/45:30 amCLT - MFE
2 stops7h 21mDelta
Deal found 10/7$369
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:00 amMFE - CLT
1 stop4h 51mUnited Airlines
Tue 10/2810:43 amCLT - MFE
2 stops12h 16mUnited Airlines
Deal found 10/8$374
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/612:31 pmMFE - CLT
2 stops10h 19mDelta
Mon 11/105:11 pmCLT - MFE
2 stops7h 48mDelta
Deal found 10/8$384
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/82:06 pmMFE - CLT
1 stop6h 30mUnited Airlines
Sat 11/224:48 pmCLT - MFE
1 stop6h 11mUnited Airlines
Deal found 10/8$390
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/97:10 amMFE - CAE
1 stop5h 21mAmerican Airlines
Sat 10/112:01 pmCAE - MFE
1 stop5h 39mAmerican Airlines
Deal found 10/8$419
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3110:38 amMFE - GSP
1 stop5h 26mAmerican Airlines
Sun 11/25:00 amGSP - MFE
1 stop5h 50mAmerican Airlines
Deal found 10/9$421

Cheap flight deals from McAllen to South Carolina

Keep the following information in mind while searching for McAllen to South Carolina flight deals. Data was last updated October 10, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$259
(American Airlines)

One-way from

$154
(Delta)
Provider with most accurate pricing for McAllen Miller Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for McAllen Miller Intl-Myrtle Beach Intl flights.
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From McAllen Miller Intl to South Carolina
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One-way flight from McAllen Miller Intl to South Carolina
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Cheapflights Fare Finder

 
Customize your flight search to find flights from McAllen to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 10, 2025.
Use the filters below to find and compare flights from McAllen to South Carolina that are best for you.

Fly from

McAllen

Fly to

South Carolina

Route

Depart

Return

Price

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Sat 11/8

5:10 pm-12:27 am

1 stop6h 17m

Charlotte Douglas

Tue 11/18

4:36 pm-11:19 pm

1 stop7h 43m

$259

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Sat 11/8

5:25 am-3:55 pm

2 stops9h 30m

Charlotte Douglas

Tue 11/18

5:30 am-12:04 pm

2 stops7h 34m

$269

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Sat 10/25

5:27 am-12:17 pm

1 stop5h 50m

Charlotte Douglas

Sun 10/26

5:37 am-9:51 am

1 stop5h 14m

$289

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Fri 10/24

7:00 am-3:53 pm

1 stop7h 53m

Charlotte Douglas

Tue 10/28

4:48 pm-9:59 pm

1 stop6h 11m

$319

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Tue 3/24

5:25 am-3:51 pm

2 stops9h 26m

Charlotte Douglas

Sat 3/28

10:07 am-4:55 pm

2 stops7h 48m

$334

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Sat 11/8

5:10 pm-12:27 am

1 stop6h 17m

Charlotte Douglas

Sat 11/22

1:25 pm-6:40 pm

1 stop6h 15m

$368

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Fri 10/31

5:25 am-4:40 pm

2 stops10h 15m

Charlotte Douglas

Tue 11/4

5:30 am-11:51 am

2 stops7h 21m

$369

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Thu 11/6

12:31 pm-11:50 pm

2 stops10h 19m

Charlotte Douglas

Mon 11/10

5:11 pm-11:59 pm

2 stops7h 48m

$384

McAllenColumbia

MFE - CAE

MFECAE

McAllen Miller Intl

Fri 3/6

5:25 am-5:58 pm

2 stops11h 33m

Columbia Metropolitan

Tue 3/10

5:10 pm-12:07 am

2 stops7h 57m

$395

McAllenGreenville

MFE - GSP

MFEGSP

McAllen Miller Intl

Fri 10/31

10:38 am-5:04 pm

1 stop5h 26m

Greenville

Sun 11/2

5:00 am-9:50 am

1 stop5h 50m

$421

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/9

Showing 1-10 of 26 results
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Best time to book a flight from McAllen to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from McAllen with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from McAllen to South Carolina

What is the cheapest time of day to fly from MFE to SC?

Find hourly flight availability from McAllen to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 10, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 52% on flights from McAllen to South Carolina by exploring options for tickets in the evening.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 10, 2025.
See what other customers who have flown with United Airlines and American Airlines from McAllen to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,968 reviews

Crew

8.1

Food

6.6

Boarding

7.7

Entertainment

7.1

Overall

7.4

Comfort

7.3

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.
United Airlines
7.4
Good
8,968 reviews
United Airlines
7.4
Good
8,968 reviews

Crew

8.1

Food

6.6

Boarding

7.7

Entertainment

7.1

Overall

7.4

Comfort

7.3

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.
American Airlines
7.2
Good
11,043 reviews
United Airlines
7.4
Good
8,968 reviews

Crew

8.1

Food

6.6

Boarding

7.7

Entertainment

7.1

Overall

7.4

Comfort

7.3

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.

Related info for your journey

Find useful and relevant information for your journey from McAllen to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from McAllen to South Carolina?

    Most people fly from McAllen Miller Intl (MFE) if they book a flight from McAllen to South Carolina. McAllen Miller Intl is conveniently located just 2.0 mi from McAllen’s city center.

  • How long is the flight from McAllen to South Carolina?

    A quick flight from McAllen to South Carolina can take about 6h 17m. American Airlines provides one of the quickest options available for as low as $259. Airlines will cover a distance of 1199 mi. This flight may include one or multiple stops.

  • What are the most popular routes from McAllen to South Carolina?

    Most travelers choose McAllen Miller Intl - Columbia Metropolitan, McAllen Miller Intl - Charlotte Douglas or McAllen Miller Intl - Savannah/Hilton Head when deciding on the best route from McAllen to South Carolina.

  • Can I find deals for flights from McAllen to South Carolina that include hotel bookings?

    Yes. In addition to deals on McAllen to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from McAllen to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from McAllen to South Carolina.

  • Can I find deals for business class flights from McAllen to South Carolina?

    Yes. Cheapflights offers flight deals from McAllen to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Top 2 airlines flying from McAllen to South Carolina

Discover the top 2 airlines that operate flights from McAllen to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$227Average$381FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$422Average$475FlexibilityNo cancel feeOn-time69%

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