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South Carolina

$159+ Cheap flights from McAllen (MFE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — CHS
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
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Find flight deals from McAllen to South Carolina

Cheapest flights from McAllen to South Carolina
Explore the most affordable flight options available from McAllen to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/92:02 pmMFE - CLT
1 stop18h 48mMultiple Airlines
Sat 12/138:55 pmCLT - MFE
1 stop13h 17mMultiple Airlines
Deal found 11/23$279
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:04 amMFE - SAV
1 stop6h 42mAmerican Airlines
Sat 1/104:33 pmSAV - MFE
1 stop7h 44mAmerican Airlines
Deal found 11/25$284
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:09 pmMFE - CLT
1 stop6h 18mAmerican Airlines
Sun 12/145:20 amCLT - MFE
1 stop6h 26mAmerican Airlines
Deal found 11/25$309
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:09 pmMFE - GSP
1 stop6h 09mAmerican Airlines
Sun 12/146:00 amGSP - MFE
1 stop5h 46mAmerican Airlines
Deal found 11/24$309
This Kiwi.com deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/92:02 pmMFE - CLT
1 stop18h 48mMultiple Airlines
Wed 12/1710:45 amCLT - MFE
1 stop22h 37mMultiple Airlines
Deal found 11/25$317
This Delta deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/95:25 amMFE - CLT
2 stops9h 48mDelta
Sat 12/136:00 amCLT - MFE
2 stops7h 09mDelta
Deal found 11/23$319
This Delta deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1012:49 pmMFE - GSP
2 stops9h 51mDelta
Sun 12/145:35 amGSP - MFE
2 stops7h 34mDelta
Deal found 11/24$319
This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:00 amMFE - CLT
1 stop4h 51mUnited Airlines
Wed 12/176:45 amCLT - MFE
1 stop5h 38mUnited Airlines
Deal found 11/24$355
This United Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:00 amMFE - CLT
1 stop4h 51mUnited Airlines
Sun 12/146:30 amCLT - MFE
2 stops10h 32mUnited Airlines
Deal found 11/25$356
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:06 amMFE - SAV
1 stop6h 43mAmerican Airlines
Sun 12/217:35 pmSAV - MFE
1 stop5h 24mAmerican Airlines
Deal found 11/24$431
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/285:04 pmMFE - GSP
1 stop5h 51mAmerican Airlines
Sun 11/306:00 amGSP - MFE
1 stop5h 21mAmerican Airlines
Deal found 11/24$633

Cheap flight deals from McAllen to South Carolina

Keep the following information in mind while searching for McAllen to South Carolina flight deals. Data was last updated November 26, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$258
(Delta)

One-way from

$159
(United Airlines)
Provider with most accurate pricing for McAllen Miller Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for McAllen Miller Intl-Myrtle Beach Intl flights.
Search Deals
From McAllen Miller Intl to South Carolina
Search Deals
One-way flight from McAllen Miller Intl to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from McAllen to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from McAllen to South Carolina that are best for you.

Fly from

McAllen

Fly to

South Carolina

Route

Depart

Return

Price

McAllenSavannah

MFE - SAV

MFESAV

McAllen Miller Intl

Tue 1/13

5:25 am-3:33 pm

2 stops9h 08m

Savannah/Hilton Head

Sat 1/17

5:30 am-12:20 pm

2 stops7h 50m

$258

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Tue 1/27

5:25 am-1:38 pm

2 stops7h 13m

Charlotte Douglas

Sat 1/31

7:59 am-5:13 pm

2 stops10h 14m

$269

McAllenGreenville

MFE - GSP

MFEGSP

McAllen Miller Intl

Tue 1/27

5:25 am-4:17 pm

2 stops9h 52m

Greenville

Sat 1/31

8:22 am-5:13 pm

2 stops9h 51m

$269

McAllenGreenville

MFE - GSP

MFEGSP

McAllen Miller Intl

Wed 1/21

1:00 pm-10:24 pm

2 stops8h 24m

Greenville

Sat 1/24

8:22 am-5:13 pm

2 stops9h 51m

$269

McAllenColumbia

MFE - CAE

MFECAE

McAllen Miller Intl

Sat 1/24

5:25 am-4:18 pm

2 stops9h 53m

Columbia Metropolitan

Tue 1/27

10:15 am-4:45 pm

2 stops7h 30m

$281

McAllenSavannah

MFE - SAV

MFESAV

McAllen Miller Intl

Fri 12/12

7:04 am-2:46 pm

1 stop6h 42m

Savannah/Hilton Head

Sat 1/10

4:33 pm-11:17 pm

1 stop7h 44m

$284

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Thu 2/19

3:41 pm-12:20 am

1 stop7h 39m

Charlotte Douglas

Sun 2/22

7:25 am-2:49 pm

1 stop8h 24m

$299

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Tue 12/9

2:02 pm-2:03 pm

2 stops23h 01m

Charlotte Douglas

Sat 12/13

8:52 am-9:12 am

1 stop25h 20m

$306

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

Wed 12/10

5:09 pm-12:27 am

1 stop6h 18m

Charlotte Douglas

Sun 12/14

5:20 am-10:46 am

1 stop6h 26m

$309

McAllenGreenville

MFE - GSP

MFEGSP

McAllen Miller Intl

Wed 12/10

5:09 pm-12:18 am

1 stop6h 09m

Greenville

Sun 12/14

6:00 am-10:46 am

1 stop5h 46m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/25

Showing 1-10 of 37 results
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Best time to book a flight from McAllen to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from McAllen with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from McAllen to South Carolina

What is the cheapest time of day to fly from MFE to SC?

Find hourly flight availability from McAllen to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 26, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 52% on flights from McAllen to South Carolina by exploring options for tickets in the evening.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 26, 2025.
See what other customers who have flown with United Airlines and American Airlines from McAllen to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,050 reviews

Crew

8.1

Entertainment

7.1

Food

6.6

Boarding

7.7

Comfort

7.3

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,050 reviews
United Airlines
7.4
Good
9,050 reviews

Crew

8.1

Entertainment

7.1

Food

6.6

Boarding

7.7

Comfort

7.3

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.2
Good
11,038 reviews
United Airlines
7.4
Good
9,050 reviews

Crew

8.1

Entertainment

7.1

Food

6.6

Boarding

7.7

Comfort

7.3

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from McAllen to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from McAllen to South Carolina?

    Most people fly from McAllen Miller Intl (MFE) if they book a flight from McAllen to South Carolina. McAllen Miller Intl is conveniently located just 2.0 mi from McAllen’s city center.

  • How long is the flight from McAllen to South Carolina?

    A quick flight from McAllen to South Carolina can take about 5h 18m. Delta provides one of the quickest options available for as low as $328. Airlines will cover a distance of 1105 mi. This flight may include one or multiple stops.

  • What are the most popular routes from McAllen to South Carolina?

    Most travelers choose McAllen Miller Intl - Charlotte Douglas, McAllen Miller Intl - Savannah/Hilton Head or McAllen Miller Intl - Greenville when deciding on the best route from McAllen to South Carolina.

  • Can I find deals for flights from McAllen to South Carolina that include hotel bookings?

    Yes. In addition to deals on McAllen to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from McAllen to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from McAllen to South Carolina.

  • Can I find deals for business class flights from McAllen to South Carolina?

    Yes. Cheapflights offers flight deals from McAllen to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for McAllen to South Carolina

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Top 2 airlines flying from McAllen to South Carolina

Discover the top 2 airlines that operate flights from McAllen to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$227Average$381FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$475Average$475FlexibilityNo cancel feeOn-time69%

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