HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$242+ Cheap flights from McAllen (MFE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — CHS
ago. 25 — sep. 11
lun. 8/25
lun. 9/1
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from McAllen to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from McAllen to South Carolina

Keep the following information in mind while searching for McAllen to South Carolina flight deals. Data was last updated agosto 20, 2025.

Round-trip from

$328
(American Airlines)

One-way from

$242
(American Airlines)
From McAllen Miller Intl to South Carolina
Search Deals
One-way flight from McAllen Miller Intl to South Carolina
Search Deals

Find flight deals from McAllen to South Carolina

Cheapest flights from McAllen to South Carolina
Explore the most affordable flight options available from McAllen to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 20, 2025.

This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/257:10 amMFE - CLT
1 stop5h 34mAmerican Airlines
lun. 10/275:37 amCLT - MFE
1 stop5h 14mAmerican Airlines
Deal found 8/18$328
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/210:38 amMFE - GSP
1 stop5h 11mAmerican Airlines
mar. 9/96:33 pmGSP - MFE
1 stop5h 17mAmerican Airlines
Deal found 8/18$328
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/212:31 pmMFE - GSP
2 stops10h 03mDelta
mar. 9/95:30 amGSP - MFE
2 stops7h 18mDelta
Deal found 8/18$359
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/29:33 amMFE - SAV
2 stops10h 38mAmerican Airlines
sáb. 9/67:31 amSAV - MFE
2 stops10h 55mAmerican Airlines
Deal found 8/17$377
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/310:53 amMFE - SAV
2 stops11h 10mAmerican Airlines
dom. 9/77:15 amSAV - MFE
1 stop5h 52mAmerican Airlines
Deal found 8/19$397
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/312:31 pmMFE - SAV
2 stops8h 06mDelta
dom. 9/75:20 amSAV - MFE
2 stops7h 28mDelta
Deal found 8/19$398
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/302:05 pmMFE - SAV
1 stop6h 54mUnited Airlines
lun. 9/13:27 pmSAV - MFE
1 stop4h 59mUnited Airlines
Deal found 8/19$441
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/255:25 amMFE - CLT
2 stops9h 30mDelta
lun. 10/275:25 pmCLT - MFE
2 stops7h 34mDelta
Deal found 8/18$469
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/215:33 amMFE - SAV
1 stop5h 06mAmerican Airlines
dom. 8/249:40 amSAV - MFE
2 stops10h 52mAmerican Airlines
Deal found 8/19$481
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/46:55 amMFE - CAE
2 stops8h 56mUnited Airlines
sáb. 10/1111:04 amCAE - MFE
2 stops11h 53mUnited Airlines
Deal found 8/20$494
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/257:00 amMFE - CLT
1 stop13h 59mUnited Airlines
lun. 10/277:44 pmCLT - MFE
2 stops27h 15mUnited Airlines
Deal found 8/18$517
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/27:25 pmMFE - CAE
2 stops25h 19mUnited Airlines
sáb. 9/66:30 amCAE - MFE
2 stops10h 32mUnited Airlines
Deal found 8/18$528

Cheapflights Fare Finder

 
Customize your flight search to find flights from McAllen to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 20, 2025.
Use the filters below to find and compare flights from McAllen to South Carolina that are best for you.

Fly from

McAllen

Fly to

South Carolina

Route

Depart

Return

Price

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

sáb. 10/25

7:10 am-1:44 pm

1 stop5h 34m

Charlotte Douglas

lun. 10/27

5:37 am-9:51 am

1 stop5h 14m

$328

McAllenGreenville

MFE - GSP

MFEGSP

McAllen Miller Intl

mar. 9/2

10:38 am-4:49 pm

1 stop5h 11m

Greenville

mar. 9/9

6:33 pm-10:50 pm

1 stop5h 17m

$328

McAllenGreenville

MFE - GSP

MFEGSP

McAllen Miller Intl

mar. 9/2

12:31 pm-11:34 pm

2 stops10h 03m

Greenville

mar. 9/9

5:30 am-11:48 am

2 stops7h 18m

$359

McAllenSavannah

MFE - SAV

MFESAV

McAllen Miller Intl

mar. 9/2

9:33 am-9:11 pm

2 stops10h 38m

Savannah/Hilton Head

sáb. 9/6

7:31 am-5:26 pm

2 stops10h 55m

$377

McAllenSavannah

MFE - SAV

MFESAV

McAllen Miller Intl

mié. 9/3

10:53 am-11:03 pm

2 stops11h 10m

Savannah/Hilton Head

dom. 9/7

7:15 am-12:07 pm

1 stop5h 52m

$397

McAllenSavannah

MFE - SAV

MFESAV

McAllen Miller Intl

mié. 9/3

12:31 pm-9:37 pm

2 stops8h 06m

Savannah/Hilton Head

dom. 9/7

5:20 am-11:48 am

2 stops7h 28m

$398

McAllenSavannah

MFE - SAV

MFESAV

McAllen Miller Intl

sáb. 8/30

2:05 pm-9:59 pm

1 stop6h 54m

Savannah/Hilton Head

lun. 9/1

3:27 pm-7:26 pm

1 stop4h 59m

$441

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

sáb. 10/25

5:25 am-3:55 pm

2 stops9h 30m

Charlotte Douglas

lun. 10/27

5:25 pm-11:59 pm

2 stops7h 34m

$469

McAllenColumbia

MFE - CAE

MFECAE

McAllen Miller Intl

sáb. 10/4

6:55 am-4:51 pm

2 stops8h 56m

Columbia Metropolitan

sáb. 10/11

11:04 am-9:57 pm

2 stops11h 53m

$494

McAllenCharlotte

MFE - CLT

MFECLT

McAllen Miller Intl

sáb. 10/25

7:00 am-9:59 pm

1 stop13h 59m

Charlotte Douglas

lun. 10/27

7:44 pm-9:59 pm

2 stops27h 15m

$517

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/19

Showing 1-10 of 21 results
1
2
3

Best time to book a flight from McAllen to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from McAllen with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from McAllen to South Carolina

What is the cheapest time of day to fly from MFE to SC?

Find hourly flight availability from McAllen to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from McAllen to South Carolina as you normally would.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated agosto 20, 2025.
See what other customers who have flown with United Airlines and American Airlines from McAllen to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,928 reviews

Entertainment

7.1

Overall

7.4

Crew

8.1

Food

6.6

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,928 reviews
United Airlines
7.4
Good
8,928 reviews

Entertainment

7.1

Overall

7.4

Crew

8.1

Food

6.6

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,928 reviews

Entertainment

7.1

Overall

7.4

Crew

8.1

Food

6.6

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from McAllen to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from McAllen to South Carolina?

    Most people fly from McAllen Miller Intl (MFE) if they book a flight from McAllen to South Carolina. McAllen Miller Intl is conveniently located just 2.0 mi from McAllen’s city center.

  • How long is the flight from McAllen to South Carolina?

    A quick flight from McAllen to South Carolina can take about 5h 34m. American Airlines provides one of the quickest options available for as low as $328. Airlines will cover a distance of 1199 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from McAllen to South Carolina one-way?

    $242 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $379 and $395, respectively.

  • What are the most popular routes from McAllen to South Carolina?

    Most travelers choose McAllen Miller Intl - Savannah/Hilton Head, McAllen Miller Intl - Charlotte Douglas or McAllen Miller Intl - Greenville when deciding on the best route from McAllen to South Carolina.

  • Can I find deals for flights from McAllen to South Carolina that include hotel bookings?

    Yes. In addition to deals on McAllen to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from McAllen to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from McAllen to South Carolina.

  • Can I find deals for business class flights from McAllen to South Carolina?

    Yes. Cheapflights offers flight deals from McAllen to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from McAllen to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from McAllen to South Carolina (average of $217). Flying from McAllen to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for McAllen to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to John F Kennedy Intl flights
Dallas/Fort Worth to LaGuardia flights
Dallas/Fort Worth to Seattle flights
Dallas/Fort Worth to Las Vegas flights
Dallas/Fort Worth to O'Hare Intl flights
Dallas/Fort Worth to Denver flights
Dallas/Fort Worth to Los Angeles flights
Dallas/Fort Worth to Newark flights
Hobby to Las Vegas flights
Dallas/Fort Worth to Midway flights
Hobby to Newark flights
Dallas/Fort Worth to Orlando flights
Hobby to John F Kennedy Intl flights
Hobby to LaGuardia flights
Dallas/Fort Worth to Boston flights
George Bush Intcntl to Las Vegas flights
George Bush Intcntl to Newark flights
Dallas/Fort Worth to Miami flights
Hobby to Denver flights
Dallas/Fort Worth to San Francisco flights
Dallas/Fort Worth to Fort Lauderdale flights
Austin to Las Vegas flights
Hobby to Seattle flights
George Bush Intcntl to John F Kennedy Intl flights
Dallas/Fort Worth to Baltimore flights
Austin to John F Kennedy Intl flights
Hobby to Los Angeles flights
Dallas/Fort Worth to Reagan-National flights
Dallas/Fort Worth to Atlanta flights
Love Field to Las Vegas flights
George Bush Intcntl to Denver flights
Austin to Newark flights
Austin to O'Hare Intl flights
George Bush Intcntl to LaGuardia flights
Dallas/Fort Worth to Dulles Intl flights
Dallas/Fort Worth to Minneapolis flights
Dallas/Fort Worth to Sky Harbor Intl flights
Love Field to Seattle flights
Dallas/Fort Worth to Portland flights
Hobby to Philadelphia flights
Austin to Seattle flights
Dallas/Fort Worth to Detroit flights
Hobby to Orlando flights
Dallas/Fort Worth to Salt Lake City flights
Love Field to LaGuardia flights
Hobby to Midway flights
Dallas/Fort Worth to San Diego flights
George Bush Intcntl to Los Angeles flights
Austin to San Francisco flights
George Bush Intcntl to Seattle flights

Top 2 airlines flying from McAllen to South Carolina

Discover the top 2 airlines that operate flights from McAllen to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$216Average$385FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$422Average$475FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.