HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$55+ Cheap flights from Manchester, NH (MHT) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — CHS
Apr 16 — Apr 231
Thu 4/16
Thu 4/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Manchester to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Manchester to South Carolina

Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/21:19 pm
MHT
-
CHS
Nonstop2h 35m
Breeze Airways
Sat 9/59:28 am
CHS
-
MHT
Nonstop2h 21m
Breeze Airways
Deal found 3/13$77
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:29 pm
MHT
-
CHS
Nonstop2h 35m
Breeze Airways
Wed 5/1310:18 am
CHS
-
MHT
Nonstop2h 21m
Breeze Airways
Deal found 3/12$104
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:18 pm
MHT
-
CHS
Nonstop2h 44m
Breeze Airways
Wed 9/239:18 am
CHS
-
MHT
Nonstop2h 20m
Breeze Airways
Deal found 3/15$107
This Breeze Airways deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/191:19 pm
MHT
-
CHS
Nonstop2h 35m
Breeze Airways
Sat 8/229:28 am
CHS
-
MHT
Nonstop2h 21m
Breeze Airways
Deal found 3/15$118
This Booking.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:19 pm
MHT
-
CHS
Nonstop2h 35m
Breeze Airways
Wed 6/310:18 am
CHS
-
MHT
Nonstop2h 21m
Breeze Airways
Deal found 3/14$124
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:29 pm
MHT
-
CHS
Nonstop2h 35m
Breeze Airways
Sat 5/169:28 am
CHS
-
MHT
Nonstop2h 21m
Breeze Airways
Deal found 3/12$127
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/309:59 am
MHT
-
CHS
Nonstop2h 35m
Breeze Airways
Fri 4/37:00 am
CHS
-
MHT
Nonstop2h 19m
Breeze Airways
Deal found 3/13$128
This Booking.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:19 pm
MHT
-
CHS
Nonstop2h 35m
Breeze Airways
Wed 5/2010:18 am
CHS
-
MHT
Nonstop2h 21m
Breeze Airways
Deal found 3/15$134
This Breeze Airways deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/29:51 am
MHT
-
CHS
1 stop11h 38m
Breeze Airways
Wed 9/910:18 am
CHS
-
MHT
Nonstop2h 21m
Breeze Airways
Deal found 3/12$137
This Breeze Airways deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:36 pm
MHT
-
MYR
Nonstop2h 25m
Breeze Airways
Mon 8/242:46 pm
MYR
-
MHT
Nonstop2h 10m
Breeze Airways
Deal found 3/14$158
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:36 pm
MHT
-
MYR
Nonstop2h 25m
Breeze Airways
Mon 8/312:46 pm
MYR
-
MHT
Nonstop2h 10m
Breeze Airways
Deal found 3/14$162
This Breeze Airways deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:36 pm
MHT
-
MYR
Nonstop2h 25m
Breeze Airways
Mon 8/242:46 pm
MYR
-
MHT
Nonstop2h 10m
Breeze Airways
Deal found 3/16$163

Find flight deals from Manchester to South Carolina

Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated March 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$77
(Kiwi.com)

One-way from

$55
(Booking.com)

Popular in

December

Cheapest in

January

Average price

$263

Good round-trip deal

$189 or less

Good one-way deal

$109 or less
Provider with most accurate pricing for Boston Logan Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Boston Logan Intl-Myrtle Beach Intl flights.
Search Deals
From Manchester to South Carolina
Search Deals
One-way flight from Manchester to South Carolina
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($28 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Manchester to South Carolina.
Search Deals
Price to beat on a one-way flight from Manchester to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ManchesterCharleston

MHT - CHS

MHTCHS

Manchester

Wed 9/2

9:25 am-2:25 pm

1 stop5h 00m

Charleston

Wed 9/9

10:00 am-2:08 pm

1 stop4h 08m

$287

ManchesterCharleston

MHT - CHS

MHTCHS

Manchester

Sun 5/10

7:30 am-4:00 pm

1 stop8h 30m

Charleston

Thu 5/14

7:00 pm-11:30 pm

1 stop4h 30m

$287

ManchesterCharleston

MHT - CHS

MHTCHS

Manchester

Mon 4/13

12:10 pm-8:50 pm

2 stops8h 40m

Charleston

Thu 4/16

7:40 am-4:00 pm

1 stop8h 20m

$292

ManchesterCharleston

MHT - CHS

MHTCHS

Manchester

Wed 9/2

9:51 am-9:29 pm

1 stop11h 38m

Charleston

Wed 9/9

9:18 am-11:38 am

Nonstop2h 20m

$305

ManchesterCharleston

MHT - CHS

MHTCHS

Manchester

Wed 4/8

5:35 am-11:00 am

1 stop5h 25m

Charleston

Wed 4/15

7:40 am-12:10 pm

1 stop4h 30m

$307

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Sat 5/16

4:45 pm-9:35 pm

1 stop4h 50m

Greenville

Tue 5/19

8:20 am-3:05 pm

1 stop6h 45m

$307

ManchesterCharleston

MHT - CHS

MHTCHS

Manchester

Tue 4/14

7:30 am-3:00 pm

2 stops7h 30m

Charleston

Tue 4/21

7:40 am-12:10 pm

1 stop4h 30m

$312

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Tue 4/14

1:58 pm-7:15 pm

1 stop5h 17m

Greenville

Wed 4/22

5:20 am-11:36 am

2 stops6h 16m

$315

ManchesterCharleston

MHT - CHS

MHTCHS

Manchester

Sun 4/5

5:35 am-3:30 pm

2 stops9h 55m

Charleston

Sat 4/11

7:00 am-11:50 am

1 stop4h 50m

$327
Quickest round-trip

ManchesterCharleston

MHT - CHS

MHTCHS

Manchester

Mon 4/27

9:59 am-12:34 pm

Nonstop2h 35m

Charleston

Mon 5/4

7:00 am-9:19 am

Nonstop2h 19m

$338

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/12

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South Carolina

What is the cheapest month to book a flight from Manchester, New Hampshire to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to South Carolina (average of $58). Flying from Manchester, New Hampshire to South Carolina in March is currently the most expensive (average of $93). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MHT to SC?

Find hourly flight availability from Manchester to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 17, 2026.

It’s optimal to fly from Manchester, New Hampshire to South Carolina in the evening. By choosing this option you can save up to 58% on the cost of your flight, compared to a flight in the afternoon.

How much does it cost to fly round-trip from Manchester, New Hampshire to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 17, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andAvelo Airlines from Manchester to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
271 reviews

Comfort

8.2

Boarding

8.3

Food

6.6

Overall

8.1

Crew

8.7

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Breeze Airways
8.1
Very good
271 reviews
Breeze Airways
8.1
Very good
271 reviews

Comfort

8.2

Boarding

8.3

Food

6.6

Overall

8.1

Crew

8.7

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Southwest
8.0
Very good
4,320 reviews
Breeze Airways
8.1
Very good
271 reviews

Comfort

8.2

Boarding

8.3

Food

6.6

Overall

8.1

Crew

8.7

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Avelo Airlines
7.6
Good
Breeze Airways
8.1
Very good
271 reviews

Comfort

8.2

Boarding

8.3

Food

6.6

Overall

8.1

Crew

8.7

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
United Airlines
7.4
Good
9,434 reviews
Breeze Airways
8.1
Very good
271 reviews

Comfort

8.2

Boarding

8.3

Food

6.6

Overall

8.1

Crew

8.7

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
American Airlines
7.1
Good
11,467 reviews
Breeze Airways
8.1
Very good
271 reviews

Comfort

8.2

Boarding

8.3

Food

6.6

Overall

8.1

Crew

8.7

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.

Related info for your journey

Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to South Carolina?

    If you book a flight to South Carolina from Manchester, you will be flying from Manchester, which is the city’s only airport. Manchester (MHT) is located 4.8 mi from the center of Manchester.

  • How popular is this Manchester, New Hampshire to South Carolina flight route?

    Within the past month, 3 users have taken a look at flights from Manchester to South Carolina.

  • How long is the flight from Manchester, New Hampshire to South Carolina?

    Airlines like Southwest, United Airlines, and American Airlines fly from Manchester, New Hampshire to South Carolina in about 5h. The time it takes to get you to your destination can typically vary by up to 2h 15m. Airlines will cover a distance of 835 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Manchester, New Hampshire to South Carolina one-way?

    $29 is the cheapest one-way deal found within the past few days, from Avelo Airlines. You may also be able to find cheap deals on Breeze Airways and United Airlines, with prices starting from $49 and $99, respectively.

  • What are the most popular routes from Manchester, New Hampshire to South Carolina?

    When deciding which route to take from Manchester, New Hampshire to South Carolina consider Manchester - Charlotte Douglas, Manchester - Charleston or Manchester - Myrtle Beach Intl as they are the most popular.

  • What are the cheapest flights from Manchester, New Hampshire to South Carolina?

    Looking at all options, your cheapest flight can be booked for $69. While the most popular route (Manchester - Charlotte Douglas) can be booked for $277 on average, our data indicates $201 when flying from Manchester, New Hampshire to South Carolina.

  • Can I find deals for flights from Manchester to South Carolina that include hotel bookings?

    Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.

  • Can I find deals for business class flights from Manchester to South Carolina?

    Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to South Carolina (average of $58). Flying from Manchester, New Hampshire to South Carolina in March is currently the most expensive (average of $93). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Manchester to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Boston to Fort Lauderdale flights
Boston to Orlando flights
Boston to Miami flights
Boston to Tampa flights
Boston to Las Vegas flights
Boston to Seattle flights
Boston to Dallas/Fort Worth flights
Boston to Los Angeles flights
Boston to Atlanta flights
Boston to San Francisco flights
Boston to West Palm Beach flights
Boston to Sky Harbor Intl flights
Boston to Charleston flights
Boston to O'Hare Intl flights
Boston to Nashville flights
Boston to Denver flights
Boston to New Orleans flights
Boston to Baltimore flights
Boston to Hobby flights
Boston to Reagan-National flights
Boston to Fort Myers flights
Boston to Dulles Intl flights
Boston to Savannah flights
Boston to Raleigh flights
Boston to San Diego flights
Boston to George Bush Intcntl flights
Boston to Austin flights
Boston to Charlotte flights
Manchester to Orlando flights
Boston to Sarasota flights
Boston to Salt Lake City flights
Boston to Detroit flights
Boston to LaGuardia flights
Boston to Newark flights
Boston to Jacksonville flights
Boston to John F Kennedy Intl flights
Boston to Love Field flights
Boston to Myrtle Beach flights
Boston to Ontario flights
Boston to Minneapolis flights
Boston to Philadelphia flights
Boston to Midway flights
Boston to Cincinnati flights
Boston to Columbus flights
Boston to Daytona Beach flights
Boston to Honolulu flights
Boston to St. Louis flights
Boston to Portland flights
Boston to Indianapolis flights
Boston to Richmond flights

Top 7 airlines flying from Manchester to South Carolina

Discover the top 7 airlines that operate flights from Manchester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
Avelo AirlinesCheapest$58Average$110FlexibilityNo cancel feeOn-timeN/A
Breeze AirwaysCheapest$81Average$191FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$87Average$166FlexibilityNo cancel feeOn-time65%
JetBlueCheapest$91Average$131FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$134Average$353FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$200Average$399FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$247Average$424FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.