$59+ Cheap flights from Harrisburg (MDT) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/4. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — CHS
Jul 23 — Jul 301
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Harrisburg to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Harrisburg to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Harrisburg to South CarolinaExplore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 23, 2026.
Explore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 23, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/83:10 pm
MDT
- MYR
Nonstop1h 36m
Allegiant Air
Thu 8/274:52 pm
MYR
- MDT
Nonstop1h 33m
Allegiant Air
Deal found 6/21![Allegiant Air logo]()
$106
This Cheapflightsfares deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:05 pm
MDT
- MYR
Nonstop1h 30m
Allegiant Air
Thu 10/296:25 pm
MYR
- MDT
Nonstop1h 36m
Allegiant Air
Deal found 6/20![Allegiant Air logo]()
$117
This Cheapflightsfares deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/253:10 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Sun 7/266:34 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$121
This Cheapflightsfares deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/54:09 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Thu 7/236:34 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/18![Allegiant Air logo]()
$125
This Cheapflightsfares deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/194:09 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Sun 7/266:34 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/21![Allegiant Air logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/194:09 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Thu 7/236:34 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/22![Allegiant Air logo]()
$131
This Cheapflightsfares deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:38 pm
MDT
- MYR
Nonstop1h 34m
Allegiant Air
Thu 10/16:27 pm
MYR
- MDT
Nonstop1h 36m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$137
This Cheapflightsfares deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:26 pm
MDT
- MYR
Nonstop1h 36m
Allegiant Air
Thu 9/34:52 pm
MYR
- MDT
Nonstop1h 31m
Allegiant Air
Deal found 6/20![Allegiant Air logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/113:58 pm
MDT
- MYR
Nonstop1h 30m
Allegiant Air
Thu 10/156:54 pm
MYR
- MDT
Nonstop1h 36m
Allegiant Air
Deal found 6/21![Allegiant Air logo]()
$141
This Cheapflightsfares deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/202:38 pm
MDT
- MYR
Nonstop1h 34m
Allegiant Air
Thu 9/245:02 pm
MYR
- MDT
Nonstop1h 31m
Allegiant Air
Deal found 6/22![Allegiant Air logo]()
$142
This Cheapflightsfares deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/264:09 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Sat 8/15:35 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$149
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:56 pm
MDT
- CHS
1 stop6h 50m
Delta
Sat 10/245:55 pm
CHS
- MDT
1 stop5h 43m
Delta
Deal found 6/23![Delta logo]()
$275
Best flights from Harrisburg to South CarolinaDiscover carefully curated flight deals from Harrisburg to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 23, 2026.
Discover carefully curated flight deals from Harrisburg to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 23, 2026.
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:56 pm
MDT
- CHS
1 stop6h 50m
Delta
Wed 10/218:20 am
CHS
- MDT
1 stop5h 49m
Delta
Deal found 6/23![Delta logo]()
$275
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:15 am
MDT
- MYR
1 stop3h 44m
United Airlines
Tue 7/143:15 pm
MYR
- MDT
1 stop6h 14m
United Airlines
Deal found 6/22![United Airlines logo]()
$304
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:00 am
MDT
- CHS
1 stop5h 07m
American Airlines
Sat 7/185:00 am
CHS
- MDT
1 stop4h 27m
American Airlines
Deal found 6/18![American Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/13:10 pm
MDT
- MYR
Nonstop1h 35m
Multiple Airlines
Sat 8/88:44 pm
MYR
- MDT
3 stops20h 24m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$479
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:56 pm
MDT
- CHS
1 stop6h 50m
Delta
Sat 10/245:55 pm
CHS
- MDT
1 stop5h 43m
Delta
Deal found 6/22![Delta logo]()
$275
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:24 pm
MDT
- SAV
1 stop5h 57m
Delta
Sat 8/226:37 pm
SAV
- MDT
1 stop4h 33m
Delta
Deal found 6/22![Delta logo]()
$285
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:30 am
MDT
- SAV
1 stop7h 46m
United Airlines
Sat 8/87:15 pm
SAV
- MDT
1 stop4h 15m
United Airlines
Deal found 6/20![United Airlines logo]()
$327
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
MDT
- GSP
1 stop5h 07m
Delta
Sun 8/236:55 am
GSP
- MDT
1 stop4h 13m
Delta
Deal found 6/18![Delta logo]()
$289
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:03 pm
MDT
- GSP
1 stop4h 06m
Delta
Sun 8/308:49 am
GSP
- MDT
1 stop5h 24m
Delta
Deal found 6/20![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:17 pm
MDT
- CHS
1 stop7h 17m
United Airlines
Wed 9/26:30 am
CHS
- MDT
1 stop7h 02m
United Airlines
Deal found 6/21![United Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:00 am
MDT
- AGS
1 stop3h 51m
American Airlines
Sun 8/307:05 am
AGS
- MDT
1 stop5h 54m
American Airlines
Deal found 6/21![American Airlines logo]()
$427
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/222:17 pm
MDT
- GSP
1 stop6h 50m
United Airlines
Wed 8/2610:33 am
GSP
- MDT
1 stop6h 19m
United Airlines
Deal found 6/19![United Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:25 pm
MDT
- SAV
1 stop5h 34m
Delta
Tue 12/227:13 pm
SAV
- MDT
1 stop4h 25m
Delta
Deal found 6/18![Delta logo]()
$297
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:22 pm
MDT
- GSP
1 stop5h 37m
Delta
Sun 7/56:45 am
GSP
- MDT
1 stop4h 26m
Delta
Deal found 6/21![Delta logo]()
$305
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/410:40 am
MDT
- GSP
1 stop6h 20m
United Airlines
Wed 7/86:10 am
GSP
- MDT
1 stop7h 25m
United Airlines
Deal found 6/19![United Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:45 am
MDT
- CAE
2 stops5h 35m
American Airlines
Fri 7/178:30 pm
CAE
- MDT
1 stop3h 55m
American Airlines
Deal found 6/23![American Airlines logo]()
$495
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/92:57 pm
MDT
- CHS
1 stop7h 10m
Delta
Thu 7/166:15 am
CHS
- MDT
1 stop4h 41m
Delta
Deal found 6/18![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/92:57 pm
MDT
- CHS
1 stop7h 10m
Delta
Sat 7/115:55 am
CHS
- MDT
1 stop5h 44m
Delta
Deal found 6/18![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:30 am
MDT
- SAV
1 stop7h 55m
United Airlines
Wed 12/167:00 pm
SAV
- MDT
1 stop5h 39m
United Airlines
Deal found 6/20![United Airlines logo]()
$426
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:00 am
MDT
- CAE
1 stop6h 39m
American Airlines
Fri 8/287:42 pm
CAE
- MDT
1 stop3h 46m
American Airlines
Deal found 6/19![American Airlines logo]()
$517
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/92:57 pm
MDT
- GSP
1 stop3h 58m
Delta
Sun 7/125:44 am
GSP
- MDT
1 stop5h 12m
Delta
Deal found 6/22![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2610:57 am
MDT
- GSP
1 stop3h 22m
United Airlines
Sat 8/296:30 am
GSP
- MDT
1 stop7h 02m
United Airlines
Deal found 6/20![United Airlines logo]()
$440
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:04 am
MDT
- CAE
1 stop6h 55m
Delta
Sun 7/125:35 am
CAE
- MDT
1 stop5h 21m
Delta
Deal found 6/22![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:52 pm
MDT
- GSP
1 stop23h 27m
United Airlines
Tue 8/187:47 pm
GSP
- MDT
1 stop3h 43m
United Airlines
Deal found 6/22![United Airlines logo]()
$453
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:22 pm
MDT
- CHS
1 stop5h 31m
Delta
Sat 7/186:24 pm
CHS
- MDT
1 stop5h 29m
Delta
Deal found 6/20![Delta logo]()
$324
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2910:40 am
MDT
- MYR
1 stop4h 52m
American Airlines
Fri 7/36:51 am
MYR
- MDT
2 stops7h 09m
American Airlines
Deal found 6/18![American Airlines logo]()
$667
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:30 am
MDT
- SAV
1 stop7h 46m
United Airlines
Sat 7/1112:10 pm
SAV
- MDT
1 stop6h 34m
United Airlines
Deal found 6/22![United Airlines logo]()
$464
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:15 am
MDT
- MYR
1 stop3h 44m
United Airlines
Fri 7/33:15 pm
MYR
- MDT
1 stop6h 14m
United Airlines
Deal found 6/19![United Airlines logo]()
$476
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:22 pm
MDT
- SAV
1 stop5h 31m
Delta
Fri 8/75:35 am
SAV
- MDT
1 stop5h 33m
Delta
Deal found 6/18![Delta logo]()
$379
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:15 am
MDT
- CHS
1 stop4h 07m
United Airlines
Sat 7/257:46 pm
CHS
- MDT
1 stop3h 44m
United Airlines
Deal found 6/18![United Airlines logo]()
$479
Last-minute flights from Harrisburg to South CarolinaDiscover last-minute flight deals from Harrisburg to South Carolina. Data last updated June 23, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to South Carolina. Data last updated June 23, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/54:09 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Thu 7/236:34 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/18![Allegiant Air logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:58 pm
MDT
- GSP
1 stop10h 32m
Allegiant Air
Mon 7/138:20 am
GSP
- MDT
1 stop27h 09m
Allegiant Air
Deal found 6/20![Allegiant Air logo]()
$290
This Cheapflightsfares deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/113:10 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Sat 7/185:35 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$161
This Cheapflightsfares deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/124:09 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Thu 7/166:34 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/164:09 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Thu 7/236:34 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/22![Allegiant Air logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/183:10 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Thu 7/236:34 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/22![Allegiant Air logo]()
$153
This Cheapflightsfares deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/183:10 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Sat 7/255:35 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$166
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:38 pm
MDT
- CHS
1 stop4h 17m
American Airlines
Wed 7/225:00 am
CHS
- MDT
1 stop6h 37m
American Airlines
Deal found 6/18![American Airlines logo]()
$275
This Cheapflightsfares deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/194:09 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Sun 7/266:34 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/21![Allegiant Air logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/194:09 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Thu 7/236:34 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/22![Allegiant Air logo]()
$131
This Cheapflightsfares deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/253:10 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Sun 7/266:34 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$121
This Cheapflightsfares deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/264:09 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Sat 8/15:35 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$149
One-way flights from Harrisburg to South CarolinaSearch for one-way flight options from Harrisburg to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 23, 2026.
Search for one-way flight options from Harrisburg to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 23, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/43:10 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Deal found 6/20![Allegiant Air logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/54:09 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Deal found 6/20![Allegiant Air logo]()
$62
This Super.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/194:09 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Deal found 6/21![Allegiant Air logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/253:10 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Deal found 6/22![Allegiant Air logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/264:09 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Deal found 6/22![Allegiant Air logo]()
$71
This Super.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/183:10 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Deal found 6/20![Allegiant Air logo]()
$82
This Super.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/284:00 pm
MDT
- MYR
Nonstop1h 36m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$104
This Trip.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/13:10 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Deal found 6/18![Allegiant Air logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/304:09 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Deal found 6/21![Allegiant Air logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:58 pm
MDT
- CLT
1 stop27h 15m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/165:58 pm
MDT
- CLT
1 stop27h 09m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/25:58 pm
MDT
- CLT
1 stop27h 09m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$121
Find flight deals from Harrisburg to South Carolina
Keep the following information in mind while searching for Harrisburg to South Carolina flight deals. Data was last updated June 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $106 (Cheapflightsfares) |
One-way from | $59 (Cheapflightsfares) |
Popular in | December |
Cheapest in | August |
Average price | $183 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2026.
Use the filters below to find and compare flights from Harrisburg to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HarrisburgCharleston
MDT - CHS
MDTCHS
Harrisburg
Wed 10/14
2:56 pm-9:46 pm
1 stop6h 50m
Charleston
Wed 10/21
8:20 am-2:09 pm
1 stop5h 49m
$275
HarrisburgCharleston
MDT - CHS
MDTCHS
Harrisburg
Wed 10/21
2:56 pm-9:46 pm
1 stop6h 50m
Charleston
Sat 10/24
5:55 pm-11:38 pm
1 stop5h 43m
$275
HarrisburgSavannah
MDT - SAV
MDTSAV
Harrisburg
Sat 8/15
6:24 pm-12:21 am
1 stop5h 57m
Savannah/Hilton Head
Sat 8/22
6:37 pm-11:10 pm
1 stop4h 33m
$285
HarrisburgGreenville
MDT - GSP
MDTGSP
Harrisburg
Wed 8/19
6:00 am-11:07 am
1 stop5h 07m
Greenville
Sun 8/23
6:55 am-11:08 am
1 stop4h 13m
$289
HarrisburgGreenville
MDT - GSP
MDTGSP
Harrisburg
Thu 8/27
3:03 pm-7:09 pm
1 stop4h 06m
Greenville
Sun 8/30
8:49 am-2:13 pm
1 stop5h 24m
$289
HarrisburgSavannah
MDT - SAV
MDTSAV
Harrisburg
Fri 12/18
6:25 pm-11:59 pm
1 stop5h 34m
Savannah/Hilton Head
Tue 12/22
7:13 pm-11:38 pm
1 stop4h 25m
$297
HarrisburgMyrtle Beach
MDT - MYR
MDTMYR
Harrisburg
Thu 7/9
6:15 am-9:59 am
1 stop3h 44m
Myrtle Beach Intl
Tue 7/14
3:15 pm-9:29 pm
1 stop6h 14m
$304
HarrisburgGreenville
MDT - GSP
MDTGSP
Harrisburg
Fri 7/3
6:22 pm-11:59 pm
1 stop5h 37m
Greenville
Sun 7/5
6:45 am-11:11 am
1 stop4h 26m
$305
HarrisburgCharleston
MDT - CHS
MDTCHS
Harrisburg
Wed 7/15
5:00 am-10:07 am
1 stop5h 07m
Charleston
Sat 7/18
5:00 am-9:27 am
1 stop4h 27m
$309
HarrisburgCharleston
MDT - CHS
MDTCHS
Harrisburg
Thu 7/9
2:57 pm-10:07 pm
1 stop7h 10m
Charleston
Thu 7/16
6:15 am-10:56 am
1 stop4h 41m
$309
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Harrisburg to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Harrisburg with our price prediction graph.
MDT-CHS
MDT-MYR
MDT-SAV
MDT-GSP
MDT-AGS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to South Carolina
MDT-USSC
MDT-CHS
MDT-MYR
MDT-SAV
MDT-GSP
What is the cheapest month to book a flight from Harrisburg to South Carolina?
Currently, July is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $56). Flying from Harrisburg to South Carolina in November is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MDT to SC?
Find hourly flight availability from Harrisburg to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 23, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Harrisburg to South Carolina as you normally would.
How much does it cost to fly round-trip from Harrisburg to South Carolina?
How far ahead should I book a flight from Harrisburg to South Carolina?
To ensure you get the cheapest price possible for a flight from Harrisburg to South Carolina, you should look to book at least 39 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 23, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAllegiant Air from Harrisburg to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Harrisburg to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Harrisburg to South Carolina by cabin class
Find flights from Harrisburg to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Harrisburg and South Carolina flights
Browse other Harrisburg and South Carolina flight options. Last updated on June 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Harrisburg to South Carolina flights
Consider these flights traveling from Harrisburg to South Carolina.
Top 4 airlines flying from Harrisburg to South Carolina
Discover the top 4 airlines that operate flights from Harrisburg to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$112 | Average$166 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$193 | Average$380 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$228 | Average$391 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$247 | Average$341 | FlexibilityNo cancel fee | On-timeN/A |