$71+ Cheap flights from Harrisburg (MDT) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — CHS
May 23 — May 301
Round-trip
1 adult, Economy
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Find cheap flights from Harrisburg to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Harrisburg to South Carolina
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Cheapest flights from Harrisburg to South CarolinaExplore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
Explore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/243:54 pm
MDT
- MYR
Nonstop1h 31m
Allegiant Air
Sat 6/135:34 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 4/19![Allegiant Air logo]()
$102
This Cheapflightsfares deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/243:54 pm
MDT
- MYR
Nonstop1h 31m
Allegiant Air
Thu 5/286:15 pm
MYR
- MDT
Nonstop1h 32m
Allegiant Air
Deal found 4/19![Allegiant Air logo]()
$114
This Cheapflightsfares deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/63:08 pm
MDT
- MYR
Nonstop1h 36m
Allegiant Air
Sat 6/135:34 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 4/20![Allegiant Air logo]()
$117
This Cheapflightsfares deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/114:00 pm
MDT
- MYR
Nonstop1h 36m
Allegiant Air
Sun 6/146:26 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 4/19![Allegiant Air logo]()
$130
This Cheapflightsfares deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/263:46 pm
MDT
- MYR
Nonstop1h 28m
Allegiant Air
Thu 4/301:58 pm
MYR
- MDT
Nonstop1h 38m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$134
This Cheapflightsfares deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/94:09 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Thu 7/166:34 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 4/19![Allegiant Air logo]()
$135
This Cheapflightsfares deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:40 am
MDT
- MYR
Nonstop1h 28m
Allegiant Air
Thu 5/72:28 pm
MYR
- MDT
Nonstop1h 38m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:16 pm
MDT
- CLT
1 stop14h 54m
Multiple Airlines
Thu 4/309:54 pm
CLT
- MDT
1 stop19h 32m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:16 pm
MDT
- CLT
1 stop17h 49m
Multiple Airlines
Thu 5/79:07 pm
CLT
- MDT
1 stop20h 19m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$223
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:15 am
MDT
- SAV
1 stop4h 37m
United Airlines
Tue 7/77:15 pm
SAV
- MDT
1 stop4h 15m
United Airlines
Deal found 4/18![United Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:16 pm
MDT
- CLT
1 stop14h 54m
Multiple Airlines
Mon 5/46:00 am
CLT
- MDT
1 stop11h 26m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:16 pm
MDT
- CLT
1 stop27h 42m
Multiple Airlines
Fri 5/18:56 am
CLT
- MDT
1 stop8h 30m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$251
Best flights from Harrisburg to South CarolinaDiscover carefully curated flight deals from Harrisburg to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
Discover carefully curated flight deals from Harrisburg to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:15 am
MDT
- SAV
1 stop4h 37m
United Airlines
Tue 7/77:15 pm
SAV
- MDT
1 stop4h 15m
United Airlines
Deal found 4/18![United Airlines logo]()
$235
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:33 pm
MDT
- CHS
1 stop4h 23m
Delta
Sat 6/137:06 am
CHS
- MDT
1 stop4h 26m
Delta
Deal found 4/20![Delta logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:10 pm
MDT
- GSP
1 stop19h 19m
Allegiant Air
Fri 7/243:10 pm
GSP
- MDT
1 stop5h 08m
Allegiant Air
Deal found 4/18![Allegiant Air logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:10 pm
MDT
- CLT
2 stops31h 52m
Multiple Airlines
Mon 5/116:00 am
CLT
- MDT
1 stop11h 26m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:51 pm
MDT
- CAE
1 stop4h 04m
American Airlines
Mon 5/256:39 pm
CAE
- MDT
1 stop4h 34m
American Airlines
Deal found 4/18![American Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/92:57 pm
MDT
- SAV
1 stop6h 13m
Delta
Sun 7/126:43 am
SAV
- MDT
1 stop4h 27m
Delta
Deal found 4/19![Delta logo]()
$311
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:30 am
MDT
- MYR
1 stop7h 48m
United Airlines
Sat 5/911:30 am
MYR
- MDT
1 stop5h 23m
United Airlines
Deal found 4/20![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/162:00 pm
MDT
- SAV
1 stop4h 53m
Delta
Wed 5/205:30 am
SAV
- MDT
1 stop5h 37m
Delta
Deal found 4/21![Delta logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:10 pm
MDT
- CLT
2 stops23h 55m
Multiple Airlines
Sun 5/107:57 pm
CLT
- MDT
1 stop12h 33m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:00 am
MDT
- CHS
1 stop5h 07m
American Airlines
Mon 7/67:50 pm
CHS
- MDT
1 stop4h 35m
American Airlines
Deal found 4/18![American Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:30 am
MDT
- CAE
1 stop7h 16m
United Airlines
Sat 7/42:29 pm
CAE
- MDT
1 stop6h 31m
United Airlines
Deal found 4/19![United Airlines logo]()
$363
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:20 am
MDT
- GSP
1 stop4h 35m
Delta
Mon 5/255:40 am
GSP
- MDT
1 stop5h 27m
Delta
Deal found 4/23![Delta logo]()
$333
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:30 am
MDT
- MYR
1 stop7h 48m
United Airlines
Sat 5/911:30 am
MYR
- MDT
1 stop5h 23m
United Airlines
Deal found 4/22![United Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
MDT
- SAV
1 stop4h 35m
Delta
Sat 5/95:29 pm
SAV
- MDT
1 stop6h 22m
Delta
Deal found 4/20![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:30 am
MDT
- MYR
1 stop7h 48m
United Airlines
Wed 5/273:08 pm
MYR
- MDT
1 stop6h 21m
United Airlines
Deal found 4/22![United Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:33 pm
MDT
- CHS
1 stop4h 23m
Delta
Mon 6/16:03 pm
CHS
- MDT
1 stop5h 48m
Delta
Deal found 4/18![Delta logo]()
$360
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:54 pm
MDT
- GSP
1 stop5h 04m
United Airlines
Tue 5/127:35 pm
GSP
- MDT
1 stop3h 53m
United Airlines
Deal found 4/23![United Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:51 pm
MDT
- CAE
1 stop4h 04m
American Airlines
Sat 5/98:12 pm
CAE
- MDT
1 stop4h 19m
American Airlines
Deal found 4/21![American Airlines logo]()
$527
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
MDT
- CAE
1 stop5h 29m
Delta
Wed 5/136:40 am
CAE
- MDT
1 stop4h 27m
Delta
Deal found 4/19![Delta logo]()
$394
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:15 am
MDT
- CAE
1 stop3h 44m
United Airlines
Sun 5/2410:31 am
CAE
- MDT
1 stop3h 19m
United Airlines
Deal found 4/19![United Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:57 pm
MDT
- AGS
1 stop6h 33m
Delta
Sat 8/157:00 am
AGS
- MDT
1 stop4h 36m
Delta
Deal found 4/20![Delta logo]()
$403
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:10 pm
MDT
- SAV
1 stop7h 03m
United Airlines
Sat 5/95:45 am
SAV
- MDT
1 stop3h 59m
United Airlines
Deal found 4/19![United Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:57 pm
MDT
- AGS
1 stop4h 52m
Delta
Fri 8/147:45 pm
AGS
- MDT
1 stop3h 55m
Delta
Deal found 4/20![Delta logo]()
$427
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:30 am
MDT
- CHS
1 stop5h 47m
United Airlines
Sun 5/106:00 am
CHS
- MDT
1 stop3h 44m
United Airlines
Deal found 4/22![United Airlines logo]()
$427
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:57 pm
MDT
- AGS
1 stop4h 52m
Delta
Fri 8/147:45 pm
AGS
- MDT
1 stop3h 55m
Delta
Deal found 4/20![Delta logo]()
$427
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:30 am
MDT
- MYR
1 stop7h 48m
United Airlines
Sun 5/103:14 pm
MYR
- MDT
1 stop6h 05m
United Airlines
Deal found 4/21![United Airlines logo]()
$453
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:00 am
MDT
- CLT
1 stop6h 24m
Delta
Tue 8/46:00 am
CLT
- MDT
1 stop5h 41m
Delta
Deal found 4/19![Delta logo]()
$451
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:15 am
MDT
- GSP
1 stop3h 43m
United Airlines
Mon 5/257:40 pm
GSP
- MDT
1 stop3h 50m
United Airlines
Deal found 4/22![United Airlines logo]()
$458
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:57 pm
MDT
- AGS
1 stop6h 33m
Delta
Sun 8/167:00 am
AGS
- MDT
1 stop4h 36m
Delta
Deal found 4/20![Delta logo]()
$453
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:15 am
MDT
- GSP
1 stop3h 43m
United Airlines
Sat 5/92:45 pm
GSP
- MDT
1 stop6h 34m
United Airlines
Deal found 4/20![United Airlines logo]()
$464
Last-minute flights from Harrisburg to South CarolinaDiscover last-minute flight deals from Harrisburg to South Carolina. Data last updated April 23, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to South Carolina. Data last updated April 23, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:16 pm
MDT
- CLT
1 stop27h 42m
Multiple Airlines
Fri 5/18:56 am
CLT
- MDT
1 stop8h 30m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$251
This Cheapflightsfares deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/263:46 pm
MDT
- MYR
Nonstop1h 28m
Allegiant Air
Thu 4/301:58 pm
MYR
- MDT
Nonstop1h 38m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:16 pm
MDT
- CLT
1 stop14h 54m
Multiple Airlines
Thu 4/309:54 pm
CLT
- MDT
1 stop19h 32m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$199
This Cheapflightsfares deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:40 am
MDT
- MYR
Nonstop1h 28m
Allegiant Air
Thu 5/72:28 pm
MYR
- MDT
Nonstop1h 38m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$137
This Cheapflightsfares deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:10 pm
MDT
- MYR
Nonstop1h 28m
Allegiant Air
Sun 5/102:28 pm
MYR
- MDT
Nonstop1h 38m
Allegiant Air
Deal found 4/18![Allegiant Air logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:16 pm
MDT
- CLT
1 stop25h 46m
Multiple Airlines
Mon 5/116:00 am
CLT
- MDT
1 stop11h 26m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$257
This Cheapflightsfares deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:10 pm
MDT
- MYR
Nonstop1h 28m
Allegiant Air
Sun 5/246:15 pm
MYR
- MDT
Nonstop1h 32m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$171
This Cheapflightsfares deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/243:54 pm
MDT
- MYR
Nonstop1h 31m
Allegiant Air
Sat 6/135:34 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 4/19![Allegiant Air logo]()
$102
This Cheapflightsfares deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/243:54 pm
MDT
- MYR
Nonstop1h 31m
Allegiant Air
Thu 5/286:15 pm
MYR
- MDT
Nonstop1h 32m
Allegiant Air
Deal found 4/19![Allegiant Air logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/243:54 pm
MDT
- MYR
Nonstop1h 31m
Multiple Airlines
Thu 5/286:00 am
MYR
- MDT
1 stop11h 07m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$176
This Cheapflightsfares deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:54 pm
MDT
- MYR
Nonstop1h 31m
Allegiant Air
Sun 5/316:15 pm
MYR
- MDT
Nonstop1h 32m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$155
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:15 am
MDT
- SAV
1 stop4h 37m
United Airlines
Tue 6/23:14 pm
SAV
- MDT
1 stop6h 15m
United Airlines
Deal found 4/21![United Airlines logo]()
$260
One-way flights from Harrisburg to South CarolinaSearch for one-way flight options from Harrisburg to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
Search for one-way flight options from Harrisburg to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/313:54 pm
MDT
- MYR
Nonstop1h 31m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/263:46 pm
MDT
- MYR
Nonstop1h 28m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/114:00 pm
MDT
- MYR
Nonstop1h 36m
Allegiant Air
Deal found 4/19![Allegiant Air logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:16 pm
MDT
- CLT
1 stop19h 55m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/185:58 pm
MDT
- CLT
1 stop18h 16m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:57 pm
MDT
- CLT
1 stop17h 37m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:16 pm
MDT
- CLT
1 stop17h 49m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:57 pm
MDT
- CLT
1 stop18h 08m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:57 pm
MDT
- MYR
1 stop26h 39m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:16 pm
MDT
- MYR
1 stop26h 20m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:58 pm
MDT
- CLT
1 stop15h 38m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:16 pm
MDT
- MYR
1 stop29h 13m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$146
Find flight deals from Harrisburg to South Carolina
Keep the following information in mind while searching for Harrisburg to South Carolina flight deals. Data was last updated April 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $102 (Cheapflightsfares) |
One-way from | $71 (Kiwi.com) |
Popular in | March |
Cheapest in | July |
Average price | $195 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Harrisburg to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HarrisburgSavannah
MDT - SAV
MDTSAV
Harrisburg
Sat 7/4
6:15 am-10:52 am
1 stop4h 37m
Savannah/Hilton Head
Tue 7/7
7:15 pm-11:30 pm
1 stop4h 15m
$235
HarrisburgCharleston
MDT - CHS
MDTCHS
Harrisburg
Tue 6/2
6:33 pm-10:56 pm
1 stop4h 23m
Charleston
Sat 6/13
7:06 am-11:32 am
1 stop4h 26m
$275
HarrisburgGreenville
MDT - GSP
MDTGSP
Harrisburg
Wed 7/22
7:10 pm-2:29 pm
1 stop19h 19m
Greenville
Fri 7/24
3:10 pm-8:18 pm
1 stop5h 08m
$278
HarrisburgSavannah
MDT - SAV
MDTSAV
Harrisburg
Thu 7/9
2:57 pm-9:10 pm
1 stop6h 13m
Savannah/Hilton Head
Sun 7/12
6:43 am-11:10 am
1 stop4h 27m
$311
HarrisburgMyrtle Beach
MDT - MYR
MDTMYR
Harrisburg
Tue 5/5
6:30 am-2:18 pm
1 stop7h 48m
Myrtle Beach Intl
Sat 5/9
11:30 am-4:53 pm
1 stop5h 23m
$319
HarrisburgCharlotte
MDT - CLT
MDTCLT
Harrisburg
Thu 5/7
12:10 pm-8:02 pm
2 stops31h 52m
Charlotte Douglas
Mon 5/11
6:00 am-5:26 pm
1 stop11h 26m
$323
HarrisburgSavannah
MDT - SAV
MDTSAV
Harrisburg
Sat 5/16
2:00 pm-6:53 pm
1 stop4h 53m
Savannah/Hilton Head
Wed 5/20
5:30 am-11:07 am
1 stop5h 37m
$329
HarrisburgGreenville
MDT - GSP
MDTGSP
Harrisburg
Wed 5/20
6:20 am-10:55 am
1 stop4h 35m
Greenville
Mon 5/25
5:40 am-11:07 am
1 stop5h 27m
$333
HarrisburgSavannah
MDT - SAV
MDTSAV
Harrisburg
Tue 5/5
6:00 am-10:35 am
1 stop4h 35m
Savannah/Hilton Head
Sat 5/9
5:29 pm-11:51 pm
1 stop6h 22m
$339
HarrisburgCharleston
MDT - CHS
MDTCHS
Harrisburg
Wed 5/27
6:33 pm-10:56 pm
1 stop4h 23m
Charleston
Mon 6/1
6:03 pm-11:51 pm
1 stop5h 48m
$360
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Harrisburg to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Harrisburg with our price prediction graph.
MDT-CLT
MDT-MYR
MDT-CHS
MDT-GSP
MDT-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to South Carolina
MDT-USSC
MDT-CLT
MDT-MYR
MDT-CHS
MDT-GSP
How far ahead should I book a flight from Harrisburg to South Carolina?
To ensure you get the cheapest price possible for a flight from Harrisburg to South Carolina, you should look to book at least 39 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Harrisburg to South Carolina?
Currently, July is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $56). Flying from Harrisburg to South Carolina in November is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Harrisburg to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 23, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAllegiant Air from Harrisburg to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Boarding
8.1
Comfort
7.9
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Boarding
8.1
Comfort
7.9
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Boarding
8.1
Comfort
7.9
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Boarding
8.1
Comfort
7.9
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Boarding
8.1
Comfort
7.9
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Harrisburg to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Harrisburg to South Carolina by cabin class
Find flights from Harrisburg to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Harrisburg and South Carolina flights
Browse other Harrisburg and South Carolina flight options. Last updated on April 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Harrisburg to South Carolina flights
Consider these flights traveling from Harrisburg to South Carolina.
Top 4 airlines flying from Harrisburg to South Carolina
Discover the top 4 airlines that operate flights from Harrisburg to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$101 | Average$160 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$213 | Average$361 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$346 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$230 | Average$350 | FlexibilityNo cancel fee | On-time69% |