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South Carolina

$98+ Cheap flights from Harrisburg (MDT) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — CHS
Mar 11 — Mar 181
Wed 3/11
Wed 3/18
1 adult, Economy
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Cheap flight deals from Harrisburg to South Carolina

Cheapest flights from Harrisburg to South Carolina
Explore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 9, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/273:08 pm
MDT
-
MYR
Nonstop1h 36m
Allegiant Air
Sat 7/45:35 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Deal found 2/7$176
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:15 am
MDT
-
SAV
1 stop4h 34m
United Airlines
Tue 3/315:45 am
SAV
-
MDT
1 stop3h 59m
United Airlines
Deal found 2/8$195
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:19 pm
MDT
-
SAV
1 stop5h 40m
Delta
Tue 4/216:50 am
SAV
-
MDT
1 stop4h 20m
Delta
Deal found 2/8$197
This Frontier deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/217:21 pm
MDT
-
CLT
1 stop12h 37m
Frontier
Mon 2/2310:42 pm
CLT
-
MDT
1 stop11h 50m
Frontier
Deal found 2/8$202
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/273:08 pm
MDT
-
MYR
Nonstop1h 36m
Allegiant Air
Sun 7/56:34 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Deal found 2/8$215
This Priceline deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1210:13 pm
MDT
-
CLT
1 stop9h 45m
Frontier
Thu 3/192:32 pm
CLT
-
MDT
1 stop6h 56m
Frontier
Deal found 2/9$218
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:06 pm
MDT
-
CLT
1 stop11h 12m
Multiple Airlines
Thu 4/169:24 pm
CLT
-
MDT
1 stop20h 02m
Multiple Airlines
Deal found 2/9$219
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:30 am
MDT
-
SAV
1 stop7h 48m
United Airlines
Tue 6/166:50 pm
SAV
-
MDT
1 stop5h 40m
United Airlines
Deal found 2/8$221
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:10 pm
MDT
-
MYR
Nonstop1h 28m
Allegiant Air
Sun 5/102:28 pm
MYR
-
MDT
Nonstop1h 38m
Allegiant Air
Deal found 2/6$223
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:26 pm
MDT
-
CLT
1 stop15h 00m
Multiple Airlines
Mon 3/169:28 pm
CLT
-
MDT
1 stop20h 24m
Multiple Airlines
Deal found 2/7$227
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1610:46 am
MDT
-
CLT
1 stop21h 27m
Multiple Airlines
Thu 2/1911:00 am
CLT
-
MDT
1 stop29h 35m
Multiple Airlines
Deal found 2/8$232
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:19 pm
MDT
-
SAV
1 stop5h 40m
Delta
Tue 4/216:50 am
SAV
-
MDT
1 stop4h 20m
Delta
Deal found 2/8$233

Find flight deals from Harrisburg to South Carolina

Keep the following information in mind while searching for Harrisburg to South Carolina flight deals. Data was last updated February 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$176
(Kiwi.com)

One-way from

$98
(Kiwi.com)

Popular in

December

Cheapest in

July

Average price

$333
Provider with most accurate pricing for Harrisburg-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Myrtle Beach Intl flights.
Search Deals
From Harrisburg to South Carolina
Search Deals
One-way flight from Harrisburg to South Carolina
Search Deals
Highest demand for flights based on searches. 25% potential increase in price ($86 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Harrisburg to South Carolina that are best for you.

Fly from

Harrisburg

Fly to

South Carolina

Route

Depart

Return

Price

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

Sat 6/27

3:08 pm-4:44 pm

Nonstop1h 36m

Myrtle Beach Intl

Sun 7/5

6:34 pm-8:08 pm

Nonstop1h 34m

$215

HarrisburgCharlotte

MDT - CLT

MDTCLT

Harrisburg

Thu 3/26

10:13 pm-7:58 am

1 stop9h 45m

Charlotte Douglas

Mon 3/30

9:28 pm-5:58 pm

1 stop20h 30m

$230

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Wed 3/4

5:55 pm-11:43 pm

1 stop5h 48m

Greenville

Tue 3/10

6:14 pm-10:50 pm

1 stop4h 36m

$239

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Sat 3/28

7:50 pm-11:59 pm

1 stop4h 09m

Savannah/Hilton Head

Wed 4/1

8:10 pm-12:35 am

1 stop4h 25m

$243

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

Sun 5/3

6:30 am-2:18 pm

1 stop7h 48m

Myrtle Beach Intl

Sat 5/9

3:14 pm-9:19 pm

1 stop6h 05m

$249

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

Fri 5/29

6:00 am-9:52 am

1 stop3h 52m

Myrtle Beach Intl

Tue 6/2

3:20 pm-9:29 pm

1 stop6h 09m

$249

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Sat 2/28

2:25 pm-7:56 pm

1 stop5h 31m

Charleston

Tue 3/3

5:27 am-11:10 am

1 stop5h 43m

$254

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Wed 7/1

2:56 pm-9:45 pm

1 stop6h 49m

Charleston

Mon 7/6

8:30 am-2:09 pm

1 stop5h 39m

$254

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Wed 2/25

12:08 pm-6:37 pm

1 stop6h 29m

Greenville

Sat 2/28

6:37 pm-11:00 pm

1 stop4h 23m

$254

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

Tue 3/10

4:40 pm-12:04 am

2 stops7h 24m

Myrtle Beach Intl

Tue 3/17

6:00 am-12:39 pm

1 stop6h 39m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/8

Showing 1-10 of 60 results
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Best time to book a flight from Harrisburg to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to South Carolina

What is the cheapest month to book a flight from Harrisburg to South Carolina?

Currently, June is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $98). Flying from Harrisburg to South Carolina in November is currently the most expensive (average of $181). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated February 9, 2026.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Harrisburg to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,178 reviews

Comfort

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,178 reviews
Delta
7.9
Good
8,178 reviews

Comfort

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,267 reviews
Delta
7.9
Good
8,178 reviews

Comfort

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,259 reviews
Delta
7.9
Good
8,178 reviews

Comfort

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Allegiant Air
7.2
Good
711 reviews
Delta
7.9
Good
8,178 reviews

Comfort

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Harrisburg to South Carolina?

    If you book a flight to South Carolina from Harrisburg, you will be flying from Harrisburg, which is the city’s only airport. Harrisburg (MDT) is located 8.5 mi from the center of Harrisburg.

  • How long is the flight from Harrisburg to South Carolina?

    Allegiant Air, Frontier, and Delta can get you from Harrisburg to South Carolina in just under 1h 36m. Your travel time can differ by up to 8h 09m. The distance between Harrisburg and South Carolina is about 465 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Harrisburg to South Carolina one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $58. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Harrisburg to South Carolina for a low price.

  • What are the most popular routes from Harrisburg to South Carolina?

    The most popular flight routes from Harrisburg to South Carolina are Harrisburg - Charleston, Harrisburg - Myrtle Beach Intl and Harrisburg - Charlotte Douglas.

  • Can I find deals for flights from Harrisburg to South Carolina that include hotel bookings?

    Yes. In addition to deals on Harrisburg to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to South Carolina.

  • Can I find deals for business class flights from Harrisburg to South Carolina?

    Yes. Cheapflights offers flight deals from Harrisburg to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to South Carolina?

    Currently, June is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $98). Flying from Harrisburg to South Carolina in November is currently the most expensive (average of $181). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Harrisburg to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Harrisburg to South Carolina

Discover the top 4 airlines that operate flights from Harrisburg to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$98Average$155FlexibilityNo cancel feeOn-time88%
DeltaCheapest$164Average$324FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$213Average$361FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$233Average$344FlexibilityNo cancel feeOn-time69%

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