$57+ Cheap flights from Harrisburg (MDT) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — CHS
May 10 — May 171
Round-trip
1 adult, Economy
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Find cheap flights from Harrisburg to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Harrisburg to South CarolinaExplore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
Explore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1012:10 pm
MDT
- MYR
Nonstop1h 28m
Allegiant Air
Thu 5/142:28 pm
MYR
- MDT
Nonstop1h 38m
Allegiant Air
Deal found 4/8![Allegiant Air logo]()
$90
This Cheapflightsfares deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:40 am
MDT
- MYR
Nonstop1h 28m
Allegiant Air
Thu 4/301:58 pm
MYR
- MDT
Nonstop1h 38m
Allegiant Air
Deal found 4/5![Allegiant Air logo]()
$106
This Cheapflightsfares deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:40 am
MDT
- MYR
Nonstop1h 28m
Allegiant Air
Thu 4/236:04 pm
MYR
- MDT
Nonstop1h 38m
Allegiant Air
Deal found 4/5![Allegiant Air logo]()
$109
This Cheapflightsfares deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/214:00 pm
MDT
- MYR
Nonstop1h 36m
Allegiant Air
Thu 6/256:26 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 4/5![Allegiant Air logo]()
$129
This Cheapflightsfares deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/63:08 pm
MDT
- MYR
Nonstop1h 36m
Allegiant Air
Sat 6/135:34 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 4/9![Allegiant Air logo]()
$131
This Cheapflightsfares deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/114:00 pm
MDT
- MYR
Nonstop1h 36m
Allegiant Air
Sun 6/146:26 pm
MYR
- MDT
Nonstop1h 34m
Allegiant Air
Deal found 4/10![Allegiant Air logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:16 pm
MDT
- CLT
1 stop14h 54m
Multiple Airlines
Fri 4/248:56 am
CLT
- MDT
1 stop8h 30m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:16 pm
MDT
- CLT
1 stop14h 54m
Multiple Airlines
Thu 4/239:54 pm
CLT
- MDT
1 stop19h 32m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/315:57 pm
MDT
- CLT
1 stop18h 08m
Multiple Airlines
Wed 6/106:40 pm
CLT
- MDT
1 stop22h 28m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:16 pm
MDT
- CLT
1 stop17h 18m
Multiple Airlines
Mon 5/116:00 am
CLT
- MDT
1 stop11h 26m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:57 pm
MDT
- CLT
1 stop17h 37m
Multiple Airlines
Wed 6/106:40 pm
CLT
- MDT
1 stop22h 28m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:57 pm
MDT
- GSP
1 stop21h 19m
Allegiant Air
Fri 5/294:10 pm
GSP
- MDT
1 stop18h 39m
Allegiant Air
Deal found 4/9![Allegiant Air logo]()
$217
Best flights from Harrisburg to South CarolinaDiscover carefully curated flight deals from Harrisburg to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
Discover carefully curated flight deals from Harrisburg to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:15 am
MDT
- SAV
1 stop4h 37m
United Airlines
Sat 7/412:10 pm
SAV
- MDT
1 stop6h 34m
United Airlines
Deal found 4/9![United Airlines logo]()
$315
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:00 am
MDT
- CHS
1 stop6h 10m
Delta
Wed 5/275:15 am
CHS
- MDT
1 stop5h 52m
Delta
Deal found 4/7![Delta logo]()
$322
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:00 am
MDT
- GSP
1 stop4h 29m
American Airlines
Tue 5/267:32 pm
GSP
- MDT
1 stop4h 54m
American Airlines
Deal found 4/9![American Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:57 pm
MDT
- GSP
2 stops25h 51m
Multiple Airlines
Mon 5/258:28 pm
GSP
- MDT
1 stop15h 01m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$386
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:30 am
MDT
- MYR
1 stop7h 48m
United Airlines
Tue 5/123:14 pm
MYR
- MDT
1 stop6h 05m
United Airlines
Deal found 4/7![United Airlines logo]()
$324
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:19 pm
MDT
- CHS
1 stop5h 31m
Delta
Sat 4/187:25 am
CHS
- MDT
1 stop6h 27m
Delta
Deal found 4/8![Delta logo]()
$361
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:15 am
MDT
- SAV
1 stop4h 37m
United Airlines
Mon 6/812:10 pm
SAV
- MDT
1 stop6h 34m
United Airlines
Deal found 4/9![United Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:34 am
MDT
- CHS
1 stop6h 33m
American Airlines
Mon 7/67:50 pm
CHS
- MDT
1 stop4h 35m
American Airlines
Deal found 4/5![American Airlines logo]()
$368
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:59 pm
MDT
- CHS
1 stop5h 17m
American Airlines
Mon 4/208:21 pm
CHS
- MDT
1 stop4h 10m
American Airlines
Deal found 4/8![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/272:41 pm
MDT
- CHS
1 stop4h 18m
United Airlines
Thu 4/306:53 pm
CHS
- MDT
1 stop5h 52m
United Airlines
Deal found 4/9![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:00 am
MDT
- MYR
2 stops9h 27m
Delta
Wed 7/156:00 am
MYR
- MDT
1 stop5h 10m
Delta
Deal found 4/8![Delta logo]()
$394
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:29 pm
MDT
- CLT
2 stops14h 24m
Multiple Airlines
Sun 5/316:00 am
CLT
- MDT
1 stop11h 07m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/222:20 pm
MDT
- GSP
1 stop5h 31m
American Airlines
Sun 5/247:32 pm
GSP
- MDT
1 stop4h 54m
American Airlines
Deal found 4/7![American Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:00 am
MDT
- GSP
1 stop4h 35m
Delta
Mon 5/257:08 am
GSP
- MDT
1 stop4h 49m
Delta
Deal found 4/7![Delta logo]()
$395
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:15 am
MDT
- CAE
1 stop3h 41m
United Airlines
Sun 6/147:45 pm
CAE
- MDT
1 stop3h 45m
United Airlines
Deal found 4/6![United Airlines logo]()
$368
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/122:56 pm
MDT
- SAV
1 stop6h 11m
Delta
Sun 6/146:43 am
SAV
- MDT
1 stop4h 28m
Delta
Deal found 4/6![Delta logo]()
$402
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:20 pm
MDT
- CHS
1 stop3h 51m
American Airlines
Mon 6/17:50 pm
CHS
- MDT
1 stop4h 36m
American Airlines
Deal found 4/5![American Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:15 am
MDT
- GSP
1 stop3h 40m
United Airlines
Sat 4/2510:33 am
GSP
- MDT
1 stop3h 22m
United Airlines
Deal found 4/5![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
MDT
- SAV
1 stop5h 30m
Delta
Sun 4/197:59 pm
SAV
- MDT
1 stop4h 00m
Delta
Deal found 4/8![Delta logo]()
$402
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:40 am
MDT
- GSP
1 stop3h 55m
American Airlines
Mon 5/257:32 pm
GSP
- MDT
1 stop4h 54m
American Airlines
Deal found 4/10![American Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:15 am
MDT
- GSP
1 stop5h 39m
United Airlines
Sun 4/267:42 pm
GSP
- MDT
1 stop3h 46m
United Airlines
Deal found 4/7![United Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1912:30 pm
MDT
- MYR
2 stops11h 09m
Delta
Mon 8/246:45 pm
MYR
- MDT
1 stop4h 55m
Delta
Deal found 4/5![Delta logo]()
$414
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/29:57 am
MDT
- CHS
1 stop6h 04m
American Airlines
Sun 5/315:00 am
CHS
- MDT
1 stop4h 28m
American Airlines
Deal found 4/9![American Airlines logo]()
$443
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:29 am
MDT
- CAE
1 stop8h 26m
United Airlines
Sun 4/267:38 pm
CAE
- MDT
1 stop3h 50m
United Airlines
Deal found 4/7![United Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:19 pm
MDT
- AGS
1 stop5h 39m
Delta
Mon 5/117:50 pm
AGS
- MDT
1 stop4h 01m
Delta
Deal found 4/6![Delta logo]()
$427
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:53 pm
MDT
- CHS
1 stop5h 39m
United Airlines
Tue 4/2810:00 am
CHS
- MDT
1 stop3h 55m
United Airlines
Deal found 4/9![United Airlines logo]()
$425
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:15 am
MDT
- CLT
1 stop5h 45m
American Airlines
Sun 5/311:12 pm
CLT
- MDT
Nonstop1h 50m
American Airlines
Deal found 4/5![American Airlines logo]()
$489
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:29 am
MDT
- SAV
1 stop6h 11m
United Airlines
Mon 4/205:45 am
SAV
- MDT
1 stop3h 59m
United Airlines
Deal found 4/8![United Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:00 am
MDT
- CLT
1 stop5h 11m
Delta
Sun 5/316:05 am
CLT
- MDT
1 stop5h 52m
Delta
Deal found 4/5![Delta logo]()
$479
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:00 am
MDT
- CLT
1 stop5h 05m
Delta
Sat 6/65:00 pm
CLT
- MDT
1 stop5h 50m
Delta
Deal found 4/6![Delta logo]()
$479
Last-minute flights from Harrisburg to South CarolinaDiscover last-minute flight deals from Harrisburg to South Carolina. Data last updated April 10, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to South Carolina. Data last updated April 10, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:40 am
MDT
- MYR
Nonstop1h 28m
Allegiant Air
Thu 4/301:58 pm
MYR
- MDT
Nonstop1h 38m
Allegiant Air
Deal found 4/5![Allegiant Air logo]()
$106
This Cheapflightsfares deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:40 am
MDT
- MYR
Nonstop1h 28m
Allegiant Air
Thu 4/236:04 pm
MYR
- MDT
Nonstop1h 38m
Allegiant Air
Deal found 4/5![Allegiant Air logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:16 pm
MDT
- CLT
1 stop14h 54m
Multiple Airlines
Fri 4/248:56 am
CLT
- MDT
1 stop8h 30m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:16 pm
MDT
- CLT
1 stop14h 54m
Multiple Airlines
Thu 4/239:54 pm
CLT
- MDT
1 stop19h 32m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:57 pm
MDT
- GSP
1 stop21h 19m
Allegiant Air
Fri 5/294:10 pm
GSP
- MDT
1 stop18h 39m
Allegiant Air
Deal found 4/9![Allegiant Air logo]()
$217
This Cheapflightsfares deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:40 am
MDT
- MYR
Nonstop1h 28m
Allegiant Air
Sun 5/102:28 pm
MYR
- MDT
Nonstop1h 38m
Allegiant Air
Deal found 4/9![Allegiant Air logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:16 pm
MDT
- CLT
1 stop17h 18m
Multiple Airlines
Mon 5/116:00 am
CLT
- MDT
1 stop11h 26m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1012:10 pm
MDT
- MYR
Nonstop1h 28m
Allegiant Air
Thu 5/142:28 pm
MYR
- MDT
Nonstop1h 38m
Allegiant Air
Deal found 4/8![Allegiant Air logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:10 pm
MDT
- MYR
Nonstop1h 28m
Allegiant Air
Sun 5/172:28 pm
MYR
- MDT
Nonstop1h 38m
Allegiant Air
Deal found 4/8![Allegiant Air logo]()
$198
This Cheapflightsfares deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:54 pm
MDT
- MYR
Nonstop1h 31m
Allegiant Air
Sun 5/316:15 pm
MYR
- MDT
Nonstop1h 32m
Allegiant Air
Deal found 4/10![Allegiant Air logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:57 pm
MDT
- CLT
1 stop17h 37m
Multiple Airlines
Wed 6/106:40 pm
CLT
- MDT
1 stop22h 28m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/315:57 pm
MDT
- CLT
1 stop18h 08m
Multiple Airlines
Wed 6/106:40 pm
CLT
- MDT
1 stop22h 28m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$199
One-way flights from Harrisburg to South CarolinaSearch for one-way flight options from Harrisburg to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
Search for one-way flight options from Harrisburg to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
This Super.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/263:46 pm
MDT
- MYR
Nonstop1h 28m
Allegiant Air
Deal found 4/7![Allegiant Air logo]()
$57
This Cheapflightsfares deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/94:22 pm
MDT
- MYR
Nonstop1h 36m
Allegiant Air
Deal found 4/5![Allegiant Air logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:16 pm
MDT
- CLT
1 stop19h 55m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$81
This Cheapflightsfares deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/24:09 pm
MDT
- MYR
Nonstop1h 35m
Allegiant Air
Deal found 4/9![Allegiant Air logo]()
$87
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:57 pm
MDT
- GSP
1 stop21h 19m
Allegiant Air
Deal found 4/9![Allegiant Air logo]()
$91
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:16 pm
MDT
- CLT
1 stop17h 18m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/44:00 pm
MDT
- MYR
Nonstop1h 36m
Allegiant Air
Deal found 4/9![Allegiant Air logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:58 pm
MDT
- MYR
1 stop26h 38m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:57 pm
MDT
- CLT
1 stop17h 37m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:58 pm
MDT
- CLT
1 stop18h 07m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:16 pm
MDT
- CLT
1 stop17h 18m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:48 pm
MDT
- GSP
1 stop21h 42m
Allegiant Air
Deal found 4/7![Allegiant Air logo]()
$133
Find flight deals from Harrisburg to South Carolina
Keep the following information in mind while searching for Harrisburg to South Carolina flight deals. Data was last updated April 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $90 (Kiwi.com) |
One-way from | $57 (Super.com) |
Popular in | March |
Cheapest in | July |
Average price | $195 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Harrisburg to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HarrisburgSavannah
MDT - SAV
MDTSAV
Harrisburg
Wed 7/1
6:15 am-10:52 am
1 stop4h 37m
Savannah/Hilton Head
Sat 7/4
12:10 pm-6:44 pm
1 stop6h 34m
$315
HarrisburgCharleston
MDT - CHS
MDTCHS
Harrisburg
Wed 5/20
6:00 am-12:10 pm
1 stop6h 10m
Charleston
Wed 5/27
5:15 am-11:07 am
1 stop5h 52m
$322
HarrisburgMyrtle Beach
MDT - MYR
MDTMYR
Harrisburg
Tue 5/5
6:30 am-2:18 pm
1 stop7h 48m
Myrtle Beach Intl
Tue 5/12
3:14 pm-9:19 pm
1 stop6h 05m
$324
HarrisburgSavannah
MDT - SAV
MDTSAV
Harrisburg
Fri 6/5
6:15 am-10:52 am
1 stop4h 37m
Savannah/Hilton Head
Mon 6/8
12:10 pm-6:44 pm
1 stop6h 34m
$330
HarrisburgCharleston
MDT - CHS
MDTCHS
Harrisburg
Mon 4/27
2:41 pm-6:59 pm
1 stop4h 18m
Charleston
Thu 4/30
6:53 pm-12:45 am
1 stop5h 52m
$349
HarrisburgGreenville
MDT - GSP
MDTGSP
Harrisburg
Tue 4/28
7:00 am-11:29 am
1 stop4h 29m
Greenville
Tue 5/26
7:32 pm-12:26 am
1 stop4h 54m
$352
HarrisburgCharleston
MDT - CHS
MDTCHS
Harrisburg
Tue 4/14
6:19 pm-11:50 pm
1 stop5h 31m
Charleston
Sat 4/18
7:25 am-1:52 pm
1 stop6h 27m
$361
HarrisburgCharleston
MDT - CHS
MDTCHS
Harrisburg
Wed 7/1
6:34 am-1:07 pm
1 stop6h 33m
Charleston
Mon 7/6
7:50 pm-12:25 am
1 stop4h 35m
$368
HarrisburgColumbia
MDT - CAE
MDTCAE
Harrisburg
Tue 6/9
6:15 am-9:56 am
1 stop3h 41m
Columbia Metropolitan
Sun 6/14
7:45 pm-11:30 pm
1 stop3h 45m
$368
HarrisburgCharleston
MDT - CHS
MDTCHS
Harrisburg
Fri 4/17
4:59 pm-10:16 pm
1 stop5h 17m
Charleston
Mon 4/20
8:21 pm-12:31 am
1 stop4h 10m
$369
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Harrisburg to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Harrisburg with our price prediction graph.
MDT-MYR
MDT-CLT
MDT-GSP
MDT-SAV
MDT-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to South Carolina
MDT-USSC
MDT-MYR
MDT-CLT
MDT-GSP
MDT-SAV
What is the cheapest month to book a flight from Harrisburg to South Carolina?
Currently, May is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $99). Flying from Harrisburg to South Carolina in November is currently the most expensive (average of $181). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Harrisburg to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 10, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAllegiant Air from Harrisburg to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Crew
8.5
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Crew
8.5
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Crew
8.5
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Crew
8.5
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Crew
8.5
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Harrisburg to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Harrisburg to South Carolina by cabin class
Find flights from Harrisburg to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Harrisburg and South Carolina flights
Browse other Harrisburg and South Carolina flight options. Last updated on April 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Harrisburg to South Carolina flights
Consider these flights traveling from Harrisburg to South Carolina.
Top 4 airlines flying from Harrisburg to South Carolina
Discover the top 4 airlines that operate flights from Harrisburg to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$101 | Average$159 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$213 | Average$356 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$351 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$228 | Average$346 | FlexibilityNo cancel fee | On-timeN/A |