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$59+ Cheap flights from Harrisburg (MDT) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — CHS
may. 6 — may. 131
mar. 5/6
mar. 5/13
1 adult, Economy
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Cheap flight deals from Harrisburg to South Carolina

Keep the following information in mind while searching for Harrisburg to South Carolina flight deals. Data was last updated mayo 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$101
(Booking.com)

One-way from

$59
(Mytrip)

Popular in

March

Cheapest in

June

Average price

$210
Provider with most accurate pricing for Harrisburg-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Harrisburg-Myrtle Beach Intl flights.
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From Harrisburg to South Carolina
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One-way flight from Harrisburg to South Carolina
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Highest demand for flights based on searches. 16% potential increase in price ($50 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Harrisburg to South Carolina

Cheapest flights from Harrisburg to South Carolina
Explore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mayo 1, 2025.

This Booking.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/54:36 pmMDT - MYR
Nonstop1h 31mAllegiant Air
sáb. 7/126:57 pmMYR - MDT
Nonstop1h 33mAllegiant Air
Deal found 4/30$101
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/244:36 pmMDT - MYR
Nonstop1h 31mMultiple Airlines
dom. 7/276:04 pmMYR - MDT
1 stop14h 21mMultiple Airlines
Deal found 4/30$188
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/285:00 amMDT - SAV
1 stop3h 29mAmerican Airlines
mié. 6/44:27 pmSAV - MDT
1 stop5h 40mAmerican Airlines
Deal found 4/30$195
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/2811:52 amMDT - GSP
1 stop27h 08mAllegiant Air
mié. 6/49:46 pmGSP - MDT
1 stop20h 17mAllegiant Air
Deal found 4/30$197
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/2910:35 amMDT - GSP
1 stop3h 42mUnited Airlines
mar. 6/106:00 amGSP - MDT
1 stop3h 35mUnited Airlines
Deal found 4/29$214
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/215:58 pmMDT - SAV
1 stop4h 33mDelta
sáb. 10/257:00 amSAV - MDT
1 stop4h 36mDelta
Deal found 4/30$217
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/286:24 amMDT - GSP
2 stops10h 07mDelta
mié. 6/45:30 amGSP - MDT
1 stop5h 31mDelta
Deal found 4/30$219
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/285:00 amMDT - CHS
1 stop5h 45mAmerican Airlines
jue. 6/126:24 pmCHS - MDT
1 stop3h 42mAmerican Airlines
Deal found 4/30$224
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/186:25 pmMDT - CAE
1 stop5h 31mDelta
mar. 6/245:40 amCAE - MDT
1 stop5h 29mDelta
Deal found 4/30$229
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/138:15 amMDT - MYR
1 stop6h 27mUnited Airlines
sáb. 9/202:47 pmMYR - MDT
1 stop4h 11mUnited Airlines
Deal found 4/30$229
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/2811:46 amMDT - CHS
1 stop4h 08mDelta
jue. 6/125:15 amCHS - MDT
2 stops10h 59mDelta
Deal found 4/30$238
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/56:18 amMDT - MYR
1 stop5h 29mAmerican Airlines
sáb. 7/126:16 pmMYR - MDT
1 stop5h 18mAmerican Airlines
Deal found 4/30$259

Cheapflights Fare Finder

Customize your flight search to find flights from Harrisburg to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mayo 1, 2025.
Use the filters below to find and compare flights from Harrisburg to South Carolina that are best for you.

Fly from

Harrisburg

Fly to

South Carolina

Route

Depart

Return

Price

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

sáb. 7/5

4:36 pm-6:07 pm

Nonstop1h 31m

Myrtle Beach Intl

sáb. 7/12

6:57 pm-8:30 pm

Nonstop1h 33m

$101

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

jue. 7/24

4:36 pm-6:07 pm

Nonstop1h 31m

Myrtle Beach Intl

dom. 7/27

6:04 pm-8:25 am

1 stop14h 21m

$188

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

mié. 5/28

5:00 am-8:29 am

1 stop3h 29m

Savannah/Hilton Head

mié. 6/4

4:27 pm-10:07 pm

1 stop5h 40m

$195

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

mié. 5/28

11:52 am-3:00 pm

1 stop27h 08m

Greenville

mié. 6/4

9:46 pm-6:03 pm

1 stop20h 17m

$197

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

jue. 5/29

10:35 am-2:17 pm

1 stop3h 42m

Greenville

mar. 6/10

6:00 am-9:35 am

1 stop3h 35m

$214

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

mar. 10/21

5:58 pm-10:31 pm

1 stop4h 33m

Savannah/Hilton Head

sáb. 10/25

7:00 am-11:36 am

1 stop4h 36m

$217

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

mié. 5/28

6:24 am-4:31 pm

2 stops10h 07m

Greenville

mié. 6/4

5:30 am-11:01 am

1 stop5h 31m

$219

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

mié. 5/28

5:00 am-10:45 am

1 stop5h 45m

Charleston

jue. 6/12

6:24 pm-10:06 pm

1 stop3h 42m

$224

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

sáb. 9/13

8:15 am-2:42 pm

1 stop6h 27m

Myrtle Beach Intl

sáb. 9/20

2:47 pm-6:58 pm

1 stop4h 11m

$229

HarrisburgColumbia

MDT - CAE

MDTCAE

Harrisburg

mié. 6/18

6:25 pm-11:56 pm

1 stop5h 31m

Columbia Metropolitan

mar. 6/24

5:40 am-11:09 am

1 stop5h 29m

$229

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 45 results
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Best time to book a flight from Harrisburg to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to South Carolina

What is the cheapest month to book a flight from Harrisburg to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $217). Flying from Harrisburg to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to SC?

Find hourly flight availability from Harrisburg to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated mayo 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Harrisburg to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated mayo 1, 2025.
To help decide which airline to fly from Harrisburg to South Carolina, see what other customers have to say about Delta, United Airlines and Allegiant Air. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
6.0
Okay
3,287 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Harrisburg to South Carolina?

    If you book a flight to South Carolina from Harrisburg, you will be flying from Harrisburg, which is the city’s only airport. Harrisburg (MDT) is located 8.5 mi from the center of Harrisburg.

  • What are the cheapest airlines to fly from Harrisburg to South Carolina one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $59. However, be on the lookout for offers from Frontier and United Airlines, as they are both options that can get you from Harrisburg to South Carolina for a low price.

  • What are the most popular routes from Harrisburg to South Carolina?

    The most popular flight routes from Harrisburg to South Carolina are Harrisburg - Charlotte Douglas, Harrisburg - Charleston and Harrisburg - Savannah/Hilton Head.

  • Can I find deals for flights from Harrisburg to South Carolina that include hotel bookings?

    Yes. In addition to deals on Harrisburg to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to South Carolina.

  • Can I find deals for business class flights from Harrisburg to South Carolina?

    Yes. Cheapflights offers flight deals from Harrisburg to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $217). Flying from Harrisburg to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Harrisburg to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Harrisburg to South Carolina

Discover the top 4 airlines that operate flights from Harrisburg to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mayo 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$103Average$150FlexibilityNo cancel feeOn-time88%
DeltaCheapest$164Average$323FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$203Average$368FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$233Average$439FlexibilityNo cancel feeOn-time69%

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