$65+ Cheap flights from Harrisburg (MDT) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — CHS
Oct 20 — Oct 271
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Harrisburg to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Harrisburg to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Harrisburg to South CarolinaExplore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 20, 2026.
Explore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 20, 2026.
This CheapOair deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/183:58 pm -
Nonstop1h 30m
Thu 10/226:25 pm -
Nonstop1h 36m
Deal found 9/18![Allegiant Air logo]()
$151
This Cheapflightsfares deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/44:07 pm -
Nonstop1h 30m
Thu 10/86:54 pm -
Nonstop1h 36m
Deal found 9/19![Allegiant Air logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/183:58 pm -
Nonstop1h 30m
Thu 10/296:25 pm -
Nonstop1h 36m
Deal found 9/16![Allegiant Air logo]()
$209
This CheapOair deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/183:58 pm -
Nonstop1h 30m
Sun 10/256:25 pm -
Nonstop1h 36m
Deal found 9/18![Allegiant Air logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:05 pm -
Nonstop1h 30m
Thu 10/296:25 pm -
Nonstop1h 36m
Deal found 9/16![Allegiant Air logo]()
$233
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/84:39 pm -
Nonstop1h 30m
Thu 10/156:54 pm -
Nonstop1h 36m
Deal found 9/15![Allegiant Air logo]()
$244
This CheapOair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/154:39 pm -
Nonstop1h 30m
Thu 10/226:25 pm -
Nonstop1h 36m
Deal found 9/17![Allegiant Air logo]()
$245
This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:05 pm -
Nonstop1h 30m
Sun 10/256:25 pm -
Nonstop1h 36m
Deal found 9/17![Allegiant Air logo]()
$253
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/202:28 pm -
Nonstop1h 34m
Thu 9/244:52 pm -
Nonstop1h 31m
Deal found 9/16![Allegiant Air logo]()
$283
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:18 pm -
1 stop5h 36m
Sat 10/246:44 pm -
1 stop4h 15m
Deal found 9/16![American Airlines logo]()
$305
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:38 pm -
1 stop4h 52m
Tue 11/177:30 pm -
1 stop4h 14m
Deal found 9/17![United Airlines logo]()
$315
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:02 am -
1 stop3h 58m
Sun 10/118:33 pm -
1 stop3h 51m
Deal found 9/17![American Airlines logo]()
$319
Best flights from Harrisburg to South CarolinaDiscover carefully curated flight deals from Harrisburg to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 20, 2026.
Discover carefully curated flight deals from Harrisburg to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 20, 2026.
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:08 pm -
1 stop6h 16m
Mon 10/267:30 pm -
1 stop4h 14m
Deal found 9/15![United Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:06 pm -
1 stop5h 51m
Mon 10/266:31 pm -
1 stop5h 08m
Deal found 9/15![Delta logo]()
$379
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:00 pm -
1 stop6h 19m
Wed 11/115:30 am -
1 stop4h 47m
Deal found 9/19![American Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/910:35 am -
1 stop3h 38m
Wed 1/136:00 am -
1 stop7h 30m
Deal found 9/19![United Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/186:00 am -
1 stop5h 18m
Mon 2/225:35 pm -
1 stop6h 03m
Deal found 9/19![Delta logo]()
$408
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/2610:35 am -
1 stop3h 35m
Sat 1/306:30 am -
1 stop7h 00m
Deal found 9/17![United Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:00 am -
1 stop3h 24m
Sun 10/188:00 am -
1 stop3h 42m
Deal found 9/15![American Airlines logo]()
$485
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:17 am -
1 stop8h 17m
Wed 12/1610:00 am -
1 stop6h 58m
Deal found 9/19![United Airlines logo]()
$415
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am -
1 stop4h 48m
Wed 10/211:59 pm -
2 stops8h 59m
Deal found 9/19![Delta logo]()
$494
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/128:19 am -
1 stop5h 41m
Wed 12/1612:15 pm -
1 stop6h 28m
Deal found 9/15![United Airlines logo]()
$434
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am -
1 stop5h 06m
Sun 10/45:55 pm -
1 stop5h 45m
Deal found 9/17![Delta logo]()
$517
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:17 am -
1 stop7h 37m
Wed 12/96:15 am -
1 stop7h 10m
Deal found 9/17![United Airlines logo]()
$444
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:56 pm -
1 stop5h 18m
Sat 10/2411:30 am -
1 stop6h 08m
Deal found 9/17![Delta logo]()
$521
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:15 am -
1 stop3h 32m
Sat 10/310:23 am -
1 stop3h 36m
Deal found 9/19![United Airlines logo]()
$459
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:56 pm -
1 stop6h 12m
Sun 10/115:30 am -
1 stop5h 24m
Deal found 9/16![Delta logo]()
$588
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:15 am -
1 stop3h 47m
Tue 10/208:00 am -
1 stop5h 27m
Deal found 9/17![United Airlines logo]()
$496
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:00 am -
1 stop5h 38m
Sun 10/186:30 am -
1 stop4h 29m
Deal found 9/18![Delta logo]()
$598
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:15 am -
1 stop3h 32m
Sun 9/276:15 am -
1 stop7h 12m
Deal found 9/15![United Airlines logo]()
$514
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
1 stop4h 43m
Tue 11/105:35 am -
2 stops10h 43m
Deal found 9/19![Delta logo]()
$608
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:30 am -
2 stops17h 45m
Sat 10/248:00 am -
1 stop5h 27m
Deal found 9/16![United Airlines logo]()
$548
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:56 pm -
1 stop5h 25m
Sun 10/255:40 am -
1 stop5h 19m
Deal found 9/19![Delta logo]()
$611
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:08 pm -
1 stop7h 25m
Fri 10/237:53 pm -
1 stop18h 06m
Deal found 9/19![United Airlines logo]()
$556
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
1 stop4h 07m
Wed 11/112:18 pm -
2 stops8h 48m
Deal found 9/19![Delta logo]()
$617
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2710:35 am -
1 stop3h 35m
Sun 3/76:30 am -
1 stop7h 02m
Deal found 9/15![United Airlines logo]()
$559
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2712:09 pm -
1 stop7h 24m
Mon 11/305:00 pm -
1 stop6h 06m
Deal found 9/15![Delta logo]()
$657
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:08 pm -
1 stop6h 16m
Mon 10/263:35 pm -
2 stops21h 49m
Deal found 9/15![United Airlines logo]()
$581
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:13 am -
2 stops8h 48m
Tue 10/202:16 pm -
2 stops8h 42m
Deal found 9/19![Delta logo]()
$703
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:15 am -
1 stop3h 29m
Sun 10/1110:23 am -
1 stop3h 36m
Deal found 9/15![United Airlines logo]()
$593
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:10 pm -
2 stops6h 18m
Wed 10/212:16 pm -
2 stops8h 42m
Deal found 9/16![Delta logo]()
$703
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:55 pm -
1 stop18h 52m
Tue 10/610:22 am -
1 stop6h 30m
Deal found 9/17![United Airlines logo]()
$613
Last-minute flights from Harrisburg to South CarolinaDiscover last-minute flight deals from Harrisburg to South Carolina. Data last updated September 20, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to South Carolina. Data last updated September 20, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/202:28 pm -
Nonstop1h 34m
Thu 9/244:52 pm -
Nonstop1h 31m
Deal found 9/16![Allegiant Air logo]()
$283
This Cheapflightsfares deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/44:07 pm -
Nonstop1h 30m
Thu 10/86:54 pm -
Nonstop1h 36m
Deal found 9/19![Allegiant Air logo]()
$184
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/84:39 pm -
Nonstop1h 30m
Thu 10/156:54 pm -
Nonstop1h 36m
Deal found 9/15![Allegiant Air logo]()
$244
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:02 am -
1 stop3h 58m
Sun 10/118:33 pm -
1 stop3h 51m
Deal found 9/17![American Airlines logo]()
$319
This CheapOair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/154:39 pm -
Nonstop1h 30m
Thu 10/226:25 pm -
Nonstop1h 36m
Deal found 9/17![Allegiant Air logo]()
$245
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:18 pm -
1 stop5h 15m
Wed 10/216:37 pm -
1 stop4h 22m
Deal found 9/19![American Airlines logo]()
$319
This CheapOair deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/183:58 pm -
Nonstop1h 30m
Thu 10/226:25 pm -
Nonstop1h 36m
Deal found 9/18![Allegiant Air logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/183:58 pm -
Nonstop1h 30m
Thu 10/296:25 pm -
Nonstop1h 36m
Deal found 9/16![Allegiant Air logo]()
$209
This CheapOair deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/183:58 pm -
Nonstop1h 30m
Sun 10/256:25 pm -
Nonstop1h 36m
Deal found 9/18![Allegiant Air logo]()
$232
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:18 pm -
1 stop5h 36m
Sat 10/246:44 pm -
1 stop4h 15m
Deal found 9/16![American Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:05 pm -
Nonstop1h 30m
Thu 10/296:25 pm -
Nonstop1h 36m
Deal found 9/16![Allegiant Air logo]()
$233
This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:05 pm -
Nonstop1h 30m
Sun 10/256:25 pm -
Nonstop1h 36m
Deal found 9/17![Allegiant Air logo]()
$253
One-way flights from Harrisburg to South CarolinaSearch for one-way flight options from Harrisburg to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 20, 2026.
Search for one-way flight options from Harrisburg to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 20, 2026.
This CheapOair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/294:05 pm -
Nonstop1h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Allegiant Air logo]()
$65
This Super.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/44:07 pm -
Nonstop1h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Allegiant Air logo]()
$90
This Super.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/113:58 pm -
Nonstop1h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Allegiant Air logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:51 pm -
1 stop11h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:22 pm -
1 stop16h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:15 pm -
1 stop14h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Allegiant Air logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/134:05 pm -
3 stops39h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1510:02 pm -
2 stops36h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:53 pm -
1 stop11h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/183:58 pm -
2 stops40h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:53 am -
2 stops24h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:13 am -
2 stops30h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$264
Find flight deals from Harrisburg to South Carolina
Keep the following information in mind while searching for Harrisburg to South Carolina flight deals. Data was last updated September 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $151 (CheapOair) |
One-way from | $65 (CheapOair) |
Popular in | December |
Cheapest in | July |
Average price | $195 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 20, 2026.
Use the filters below to find and compare flights from Harrisburg to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HarrisburgGreenville
MDT Harrisburg - GSP Greenville
MDTGSP
Harrisburg
Sat 10/10
6:15 pm-8:54 am
1 stop14h 39m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$223
HarrisburgSavannah
MDT Harrisburg - SAV Savannah/Hilton Head
MDTSAV
Harrisburg
Fri 10/30
9:13 am-4:02 pm
2 stops30h 49m
Savannah/Hilton Head
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$264
HarrisburgGreenville
MDT Harrisburg - GSP Greenville
MDTGSP
Harrisburg
Sat 10/10
11:53 am-8:49 pm
2 stops32h 56m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$267
HarrisburgCharleston
MDT Harrisburg - CHS Charleston
MDTCHS
Harrisburg
Sun 1/3
1:21 pm-9:48 am
2 stops20h 27m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$268
Quickest round-trip
HarrisburgColumbia
MDT Harrisburg - CAE Columbia Metropolitan
MDTCAE
Harrisburg
Sun 10/25
5:00 am-8:27 am
1 stop3h 27m
Columbia Metropolitan
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$274
HarrisburgMyrtle Beach
MDT Harrisburg - MYR Myrtle Beach Intl
MDTMYR
Harrisburg
Sun 10/11
6:15 am-9:44 am
1 stop3h 29m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$274
HarrisburgMyrtle Beach
MDT Harrisburg - MYR Myrtle Beach Intl
MDTMYR
Harrisburg
Fri 1/8
12:51 pm-4:26 pm
1 stop3h 35m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$283
HarrisburgMyrtle Beach
MDT Harrisburg - MYR Myrtle Beach Intl
MDTMYR
Harrisburg
Thu 10/29
3:28 pm-10:02 pm
1 stop6h 34m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$283
HarrisburgSavannah
MDT Harrisburg - SAV Savannah/Hilton Head
MDTSAV
Harrisburg
Fri 10/30
2:56 pm-9:17 pm
1 stop6h 21m
Savannah/Hilton Head
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$284
HarrisburgCharlotte
MDT Harrisburg - CLT Charlotte Douglas
MDTCLT
Harrisburg
Fri 10/16
2:56 pm-9:45 pm
1 stop6h 49m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$284
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Harrisburg to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Harrisburg with our price prediction graph.
MDT-GSP
MDT-SAV
MDT-CAE
MDT-MYR
MDT-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to South Carolina
MDT-USSC
MDT-GSP
MDT-SAV
MDT-CAE
MDT-MYR
What is the cheapest month to book a flight from Harrisburg to South Carolina?
Currently, June is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $201). Flying from Harrisburg to South Carolina in March is currently the most expensive (average of $424). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Harrisburg to South Carolina?
Airfare is below average for this route at the moment.
Harrisburg to South Carolina flights typically cost between $387 and $543 in October.The cheapest round-trip price found within the last 5 days was $305 on American Airlines (Oct 21-Oct 24).
How far ahead should I book a flight from Harrisburg to South Carolina?
To ensure you get the cheapest price possible for a flight from Harrisburg to South Carolina, you should look to book at least 71 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 20, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAllegiant Air from Harrisburg to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Food
7.2
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Boarding
8.1
Food
7.2
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Boarding
8.1
Food
7.2
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Boarding
8.1
Food
7.2
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Boarding
8.1
Food
7.2
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Harrisburg to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Harrisburg to South Carolina by cabin class
Find flights from Harrisburg to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Harrisburg and South Carolina flights
Browse other Harrisburg and South Carolina flight options. Last updated on September 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Harrisburg to South Carolina flights
Consider these flights traveling from Harrisburg to South Carolina.
Top 4 airlines flying from Harrisburg to South Carolina
Discover the top 4 airlines that operate flights from Harrisburg to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$122 | Average$177 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$228 | Average$375 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$254 | Average$424 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$269 | Average$398 | FlexibilityNo cancel fee | On-timeN/A |