$123+ Cheap flights from South Carolina to Harrisburg (MDT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDT
Oct 21 — Oct 281
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Harrisburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Harrisburg
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Cheapest flights from South Carolina to HarrisburgExplore the most affordable flight options available from South Carolina to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
Explore the most affordable flight options available from South Carolina to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
This CheapOair deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:25 pm -
Nonstop1h 36m
Sun 10/254:05 pm -
Nonstop1h 30m
Deal found 9/20![Allegiant Air logo]()
$123
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:54 pm -
Nonstop1h 36m
Sun 10/254:05 pm -
Nonstop1h 30m
Deal found 9/16![Allegiant Air logo]()
$197
This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:54 pm -
Nonstop1h 36m
Sun 10/113:58 pm -
Nonstop1h 30m
Deal found 9/17![Allegiant Air logo]()
$238
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/244:52 pm -
Nonstop1h 31m
Sun 9/272:28 pm -
Nonstop1h 34m
Deal found 9/16![Allegiant Air logo]()
$253
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:05 am -
1 stop4h 18m
Sat 12/512:40 pm -
1 stop5h 56m
Deal found 9/20![American Airlines logo]()
$305
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:15 pm -
1 stop4h 14m
Sat 10/316:15 am -
1 stop4h 45m
Deal found 9/20![United Airlines logo]()
$315
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:33 pm -
1 stop3h 51m
Tue 10/2010:42 am -
1 stop4h 22m
Deal found 9/16![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:23 am -
1 stop3h 36m
Sun 10/186:15 am -
1 stop3h 29m
Deal found 9/20![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:20 am -
1 stop3h 51m
Sat 10/1712:18 pm -
1 stop5h 36m
Deal found 9/17![American Airlines logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:25 pm -
Nonstop1h 36m
Sun 10/259:56 pm -
2 stops36h 09m
Deal found 9/19![Multiple Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:07 pm -
1 stop3h 52m
Tue 11/36:00 am -
1 stop3h 44m
Deal found 9/17![American Airlines logo]()
$327
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:15 am -
1 stop3h 56m
Sat 10/318:24 am -
1 stop5h 07m
Deal found 9/19![American Airlines logo]()
$329
Best flights from South Carolina to HarrisburgDiscover carefully curated flight deals from South Carolina to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
Discover carefully curated flight deals from South Carolina to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:33 pm -
1 stop3h 51m
Thu 10/296:43 am -
1 stop4h 01m
Deal found 9/17![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:00 am -
1 stop3h 59m
Mon 11/26:25 pm -
1 stop4h 26m
Deal found 9/21![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:38 pm -
1 stop6h 23m
Wed 10/2810:30 am -
1 stop4h 15m
Deal found 9/16![United Airlines logo]()
$395
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:33 pm -
1 stop3h 51m
Tue 10/2010:42 am -
1 stop4h 22m
Deal found 9/16![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:33 pm -
1 stop3h 51m
Thu 10/2912:18 pm -
1 stop5h 04m
Deal found 9/18![American Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:47 pm -
2 stops19h 38m
Mon 10/128:29 pm -
1 stop13h 36m
Deal found 9/16![Multiple Airlines logo]()
$702
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:31 pm -
1 stop5h 08m
Sun 10/256:06 pm -
1 stop5h 51m
Deal found 9/20![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 am -
1 stop4h 17m
Tue 10/2011:02 am -
1 stop3h 50m
Deal found 9/20![American Airlines logo]()
$322
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:53 pm -
1 stop3h 36m
Sun 9/272:08 pm -
1 stop7h 25m
Deal found 9/17![United Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:30 am -
1 stop5h 29m
Mon 10/262:56 pm -
1 stop6h 12m
Deal found 9/18![Delta logo]()
$408
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/101:13 pm -
1 stop5h 41m
Tue 10/137:06 pm -
1 stop4h 50m
Deal found 9/20![American Airlines logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:00 am -
1 stop5h 27m
Sat 10/172:08 pm -
1 stop7h 33m
Deal found 9/16![United Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:00 am -
1 stop4h 03m
Mon 10/56:09 pm -
1 stop4h 51m
Deal found 9/16![Delta logo]()
$419
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:53 am -
1 stop7h 59m
Tue 10/66:30 am -
1 stop8h 00m
Deal found 9/17![United Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:12 pm -
1 stop4h 12m
Sat 10/175:00 am -
1 stop3h 37m
Deal found 9/17![American Airlines logo]()
$373
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:00 am -
1 stop3h 42m
Mon 10/1210:02 am -
1 stop5h 19m
Deal found 9/17![American Airlines logo]()
$398
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2211:30 am -
2 stops12h 20m
Tue 12/16:00 am -
1 stop4h 41m
Deal found 9/18![Delta logo]()
$498
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:20 am -
1 stop7h 07m
Sat 10/106:30 am -
1 stop7h 03m
Deal found 9/21![United Airlines logo]()
$499
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:33 pm -
1 stop3h 51m
Wed 10/1410:02 am -
1 stop5h 19m
Deal found 9/20![American Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:30 am -
1 stop6h 57m
Tue 10/66:30 am -
1 stop7h 34m
Deal found 9/17![United Airlines logo]()
$514
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:33 pm -
1 stop5h 51m
Sun 10/185:00 am -
1 stop5h 11m
Deal found 9/21![American Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:16 pm -
2 stops8h 42m
Sun 10/256:13 am -
1 stop4h 29m
Deal found 9/16![Delta logo]()
$608
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:50 pm -
1 stop3h 39m
Wed 10/72:08 pm -
1 stop7h 07m
Deal found 9/18![United Airlines logo]()
$581
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:00 am -
1 stop4h 11m
Sat 10/245:49 pm -
1 stop6h 10m
Deal found 9/19![American Airlines logo]()
$443
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
2 stops10h 14m
Wed 10/76:00 am -
1 stop4h 07m
Deal found 9/18![Delta logo]()
$618
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:45 am -
1 stop6h 07m
Wed 10/72:08 pm -
1 stop7h 09m
Deal found 9/18![United Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:00 am -
1 stop6h 23m
Mon 11/235:46 pm -
1 stop3h 58m
Deal found 9/19![American Airlines logo]()
$457
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:12 pm -
1 stop4h 38m
Mon 11/235:05 pm -
2 stops6h 42m
Deal found 9/19![Delta logo]()
$636
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:43 pm -
1 stop4h 01m
Mon 11/28:13 pm -
2 stops20h 43m
Deal found 9/21![United Airlines logo]()
$623
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:59 am -
1 stop4h 06m
Mon 11/305:00 am -
1 stop3h 33m
Deal found 9/20![American Airlines logo]()
$481
Last-minute flights from South Carolina to HarrisburgDiscover last-minute flight deals from South Carolina to Harrisburg. Data last updated September 21, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Harrisburg. Data last updated September 21, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/244:52 pm -
Nonstop1h 31m
Sun 9/272:28 pm -
Nonstop1h 34m
Deal found 9/16![Allegiant Air logo]()
$253
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:54 pm -
Nonstop1h 36m
Sun 10/254:05 pm -
Nonstop1h 30m
Deal found 9/16![Allegiant Air logo]()
$197
This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:54 pm -
Nonstop1h 36m
Sun 10/113:58 pm -
Nonstop1h 30m
Deal found 9/17![Allegiant Air logo]()
$238
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:20 am -
1 stop3h 51m
Sat 10/1712:18 pm -
1 stop5h 36m
Deal found 9/17![American Airlines logo]()
$322
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:10 pm -
1 stop4h 29m
Sat 10/176:00 am -
1 stop7h 18m
Deal found 9/20![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:23 am -
1 stop3h 36m
Sun 10/186:15 am -
1 stop3h 29m
Deal found 9/20![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:33 pm -
1 stop3h 51m
Tue 10/2010:42 am -
1 stop4h 22m
Deal found 9/16![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:07 pm -
1 stop3h 52m
Tue 11/36:00 am -
1 stop3h 44m
Deal found 9/17![American Airlines logo]()
$327
This CheapOair deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:25 pm -
Nonstop1h 36m
Sun 10/254:05 pm -
Nonstop1h 30m
Deal found 9/20![Allegiant Air logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:25 pm -
Nonstop1h 36m
Sun 10/259:56 pm -
2 stops36h 09m
Deal found 9/19![Multiple Airlines logo]()
$323
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:15 pm -
1 stop4h 14m
Sat 10/316:15 am -
1 stop4h 45m
Deal found 9/20![United Airlines logo]()
$315
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:15 am -
1 stop3h 56m
Sat 10/318:24 am -
1 stop5h 07m
Deal found 9/19![American Airlines logo]()
$329
One-way flights from South Carolina to HarrisburgSearch for one-way flight options from South Carolina to Harrisburg. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
Search for one-way flight options from South Carolina to Harrisburg. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
This Super.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/244:52 pm -
Nonstop1h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Allegiant Air logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:05 am -
3 stops33h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1711:52 am -
3 stops51h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:32 am -
2 stops31h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$186
This Super.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:13 pm -
Nonstop1h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Allegiant Air logo]()
$191
This Super.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/274:52 pm -
Nonstop1h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Allegiant Air logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/159:47 pm -
3 stops38h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:37 am -
2 stops28h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:15 pm -
1 stop19h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Allegiant Air logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:39 pm -
2 stops23h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:05 am -
3 stops30h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:59 am -
1 stop6h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Allegiant Air logo]()
$226
Find flight deals from South Carolina to Harrisburg
Keep the following information in mind while searching for South Carolina to Harrisburg flight deals. Data was last updated September 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $123 (CheapOair) |
Popular in | November |
Cheapest in | February |
Average price | $340 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
Use the filters below to find and compare flights from South Carolina to Harrisburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachHarrisburg
MYR Myrtle Beach Intl - MDT Harrisburg
MYRMDT
Myrtle Beach Intl
Sun 10/18
6:13 pm-7:49 pm
Nonstop1h 36m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$191
Quickest round-trip
Myrtle BeachHarrisburg
MYR Myrtle Beach Intl - MDT Harrisburg
MYRMDT
Myrtle Beach Intl
Sun 9/27
4:52 pm-6:23 pm
Nonstop1h 31m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$194
GreenvilleHarrisburg
GSP Greenville - MDT Harrisburg
GSPMDT
Greenville
Fri 10/16
3:15 pm-11:03 am
1 stop19h 48m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$206
GreenvilleHarrisburg
GSP Greenville - MDT Harrisburg
GSPMDT
Greenville
Wed 12/23
4:02 pm-8:36 pm
1 stop4h 34m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$231
GreenvilleHarrisburg
GSP Greenville - MDT Harrisburg
GSPMDT
Greenville
Wed 12/23
3:13 pm-12:31 pm
2 stops21h 18m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$268
Myrtle BeachHarrisburg
MYR Myrtle Beach Intl - MDT Harrisburg
MYRMDT
Myrtle Beach Intl
Sun 11/22
6:51 pm-11:50 pm
1 stop4h 59m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$283
SavannahHarrisburg
SAV Savannah/Hilton Head - MDT Harrisburg
SAVMDT
Savannah/Hilton Head
Thu 10/22
5:30 am-10:59 am
1 stop5h 29m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$284
SavannahHarrisburg
SAV Savannah/Hilton Head - MDT Harrisburg
SAVMDT
Savannah/Hilton Head
Fri 10/23
6:31 pm-11:39 pm
1 stop5h 08m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$284
CharlestonHarrisburg
CHS Charleston - MDT Harrisburg
CHSMDT
Charleston
Sun 10/4
2:13 pm-2:48 pm
1 stop24h 35m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$295
Myrtle BeachHarrisburg
MYR Myrtle Beach Intl - MDT Harrisburg
MYRMDT
Myrtle Beach Intl
Sun 10/18
5:00 am-9:11 am
1 stop4h 11m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$303
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Harrisburg
Have a flexible travel schedule? Discover the best time to fly to Harrisburg from South Carolina with our price prediction graph.
GSP-MDT
SAV-MDT
MYR-MDT
CHS-MDT
CLT-MDT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Harrisburg
USSC-MDT
GSP-MDT
SAV-MDT
MYR-MDT
CHS-MDT
What is the cheapest month to book a flight from South Carolina to Harrisburg?
Currently, September is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $308). Flying from South Carolina to Harrisburg in March is currently the most expensive (average of $490). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from South Carolina to Harrisburg?
Airfare is below average for this route at the moment.
South Carolina to Harrisburg flights typically cost between $332 and $446 in November.The cheapest round-trip price found within the last 5 days was $305 on American Airlines (Nov 25-Dec 5).
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Harrisburg?
Book flights to Harrisburg if you plan to visit one of these locationsHershey
Mechanicsburg
Camp Hill
Carlisle
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for South Carolina to Harrisburg
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Harrisburg by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Harrisburg by cabin class
Find flights from South Carolina to Harrisburg, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Harrisburg flights
Browse other South Carolina and Harrisburg flight options. Last updated on September 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
South Carolina to Harrisburg flights
Consider these flights traveling from South Carolina to Harrisburg.
Top 4 airlines flying from South Carolina to Harrisburg
Discover the top 4 airlines that operate flights from South Carolina to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$113 | Average$164 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$238 | Average$437 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$263 | Average$345 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$280 | Average$338 | FlexibilityNo cancel fee | On-time69% |