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South Carolina

$63+ Cheap flights from Harrisburg (MDT) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/13. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — CHS
jul. 8 — jul. 151
mar. 7/8
mar. 7/15
1 adult, Economy
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Cheap flight deals from Harrisburg to South Carolina

Keep the following information in mind while searching for Harrisburg to South Carolina flight deals. Data was last updated julio 3, 2025.

Round-trip from

$98
(Gotogate)

One-way from

$63
(Kiwi.com)

Popular in

January

Cheapest in

June

Average price

$150
From Harrisburg to South Carolina
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One-way flight from Harrisburg to South Carolina
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Highest demand for flights based on searches. 29% potential increase in price ($105 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Harrisburg to South Carolina

Cheapest flights from Harrisburg to South Carolina
Explore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 3, 2025.

This Gotogate deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/104:36 pmMDT - MYR
Nonstop1h 31mAllegiant Air
jue. 8/146:55 pmMYR - MDT
Nonstop1h 35mAllegiant Air
Deal found 7/2$98
This Mytrip deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 7/274:36 pmMDT - MYR
Nonstop1h 31mMultiple Airlines
jue. 7/316:10 amMYR - MDT
1 stop9h 36mMultiple Airlines
Deal found 7/1$161
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/44:45 pmMDT - SAV
1 stop3h 48mAmerican Airlines
sáb. 10/117:38 amSAV - MDT
1 stop4h 02mAmerican Airlines
Deal found 7/3$195
This Mytrip deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/18:51 pmMDT - CLT
2 stops25h 25mMultiple Airlines
vie. 8/89:24 amCLT - MDT
1 stop10h 37mMultiple Airlines
Deal found 7/2$203
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/26:00 amMDT - SAV
1 stop5h 14mDelta
sáb. 9/68:20 amSAV - MDT
1 stop4h 35mDelta
Deal found 7/2$217
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/146:10 amMDT - GSP
1 stop4h 27mDelta
mar. 8/196:25 pmGSP - MDT
1 stop4h 34mDelta
Deal found 7/3$229
This Mytrip deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/147:29 pmMDT - CAE
1 stop15h 15mMultiple Airlines
dom. 8/179:32 pmCAE - MDT
2 stops23h 00mMultiple Airlines
Deal found 7/1$237
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/67:58 amMDT - MYR
1 stop3h 28mAmerican Airlines
mar. 8/128:08 amMYR - MDT
2 stops6h 48mAmerican Airlines
Deal found 7/1$246
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/216:29 pmMDT - CHS
1 stop4h 09mDelta
dom. 8/246:59 pmCHS - MDT
1 stop4h 30mDelta
Deal found 7/1$249
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/291:00 pmMDT - GSP
1 stop5h 03mAmerican Airlines
dom. 8/35:30 amGSP - MDT
1 stop4h 17mAmerican Airlines
Deal found 7/3$268
This Frontier deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/2210:43 amMDT - CLT
1 stop10h 03mFrontier
dom. 8/319:41 pmCLT - MDT
1 stop12h 17mFrontier
Deal found 7/3$274
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/96:15 amMDT - GSP
1 stop3h 37mUnited Airlines
lun. 7/147:45 pmGSP - MDT
1 stop3h 45mUnited Airlines
Deal found 7/1$277

Cheapflights Fare Finder

Customize your flight search to find flights from Harrisburg to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
Use the filters below to find and compare flights from Harrisburg to South Carolina that are best for you.

Fly from

Harrisburg

Fly to

South Carolina

Route

Depart

Return

Price

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

dom. 8/10

4:36 pm-6:07 pm

Nonstop1h 31m

Myrtle Beach Intl

jue. 8/14

6:55 pm-8:30 pm

Nonstop1h 35m

$98

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

dom. 7/27

4:36 pm-6:07 pm

Nonstop1h 31m

Myrtle Beach Intl

jue. 7/31

6:10 am-3:46 pm

1 stop9h 36m

$153

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

sáb. 10/4

4:45 pm-8:33 pm

1 stop3h 48m

Savannah/Hilton Head

sáb. 10/11

7:38 am-11:40 am

1 stop4h 02m

$195

HarrisburgCharlotte

MDT - CLT

MDTCLT

Harrisburg

vie. 8/1

8:51 pm-10:16 pm

2 stops25h 25m

Charlotte Douglas

vie. 8/8

9:24 am-8:01 pm

1 stop10h 37m

$203

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

mar. 9/2

6:00 am-11:14 am

1 stop5h 14m

Savannah/Hilton Head

sáb. 9/6

8:20 am-12:55 pm

1 stop4h 35m

$217

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

jue. 8/14

6:10 am-10:37 am

1 stop4h 27m

Greenville

mar. 8/19

6:25 pm-10:59 pm

1 stop4h 34m

$229

HarrisburgColumbia

MDT - CAE

MDTCAE

Harrisburg

jue. 8/14

7:29 pm-10:44 am

1 stop15h 15m

Columbia Metropolitan

dom. 8/17

9:32 pm-8:32 pm

2 stops23h 00m

$237

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

sáb. 9/6

6:00 am-10:11 am

1 stop4h 11m

Myrtle Beach Intl

sáb. 9/13

6:00 am-12:58 pm

1 stop6h 58m

$241

HarrisburgMyrtle Beach

MDT - MYR

MDTMYR

Harrisburg

mié. 8/6

7:58 am-11:26 am

1 stop3h 28m

Myrtle Beach Intl

mar. 8/12

8:08 am-2:56 pm

2 stops6h 48m

$246

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

jue. 8/21

6:29 pm-10:38 pm

1 stop4h 09m

Charleston

dom. 8/24

6:59 pm-11:29 pm

1 stop4h 30m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/3

Showing 1-10 of 47 results
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Best time to book a flight from Harrisburg to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to South Carolina

What is the cheapest month to book a flight from Harrisburg to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $217). Flying from Harrisburg to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to SC?

Find hourly flight availability from Harrisburg to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Harrisburg to South Carolina as you normally would.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated julio 3, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Harrisburg to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,970 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,970 reviews
Delta
8.0
Very good
7,970 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,845 reviews
Delta
8.0
Very good
7,970 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,970 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.2
Good
709 reviews
Delta
8.0
Very good
7,970 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Frontier
5.9
Fair
3,284 reviews
Delta
8.0
Very good
7,970 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Harrisburg to South Carolina?

    If you book a flight to South Carolina from Harrisburg, you will be flying from Harrisburg, which is the city’s only airport. Harrisburg (MDT) is located 8.5 mi from the center of Harrisburg.

  • What are the cheapest airlines to fly from Harrisburg to South Carolina one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $63. However, be on the lookout for offers from Frontier and Delta, as they are both options that can get you from Harrisburg to South Carolina for a low price.

  • What are the most popular routes from Harrisburg to South Carolina?

    The most popular flight routes from Harrisburg to South Carolina are Harrisburg - Charlotte Douglas, Harrisburg - Charleston and Harrisburg - Savannah/Hilton Head.

  • Can I find deals for flights from Harrisburg to South Carolina that include hotel bookings?

    Yes. In addition to deals on Harrisburg to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to South Carolina.

  • Can I find deals for business class flights from Harrisburg to South Carolina?

    Yes. Cheapflights offers flight deals from Harrisburg to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $217). Flying from Harrisburg to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Harrisburg to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Harrisburg to South Carolina

Discover the top 4 airlines that operate flights from Harrisburg to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$99Average$154FlexibilityNo cancel feeOn-time88%
DeltaCheapest$164Average$318FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$203Average$361FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$233Average$422FlexibilityNo cancel feeOn-time69%

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