South Carolina

$62+ Cheap flights from Harrisburg (MDT) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/5. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — CHS
Jul 8 — Jul 151
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Harrisburg to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Harrisburg to South Carolina

Cheapest flights from Harrisburg to South Carolina
Explore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/83:10 pm
MDT
-
MYR
Nonstop1h 36m
Allegiant Air
Thu 8/274:52 pm
MYR
-
MDT
Nonstop1h 33m
Allegiant Air
Deal found 6/3$102
This Cheapflightsfares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/253:10 pm
MDT
-
MYR
Nonstop1h 35m
Allegiant Air
Sun 7/266:34 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/3$129
This Mytrip deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/54:09 pm
MDT
-
MYR
Nonstop1h 35m
Allegiant Air
Thu 7/166:34 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/6$130
This Cheapflightsfares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:26 pm
MDT
-
MYR
Nonstop1h 36m
Allegiant Air
Sun 8/304:52 pm
MYR
-
MDT
Nonstop1h 33m
Allegiant Air
Deal found 6/3$137
This Gotogate deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/194:09 pm
MDT
-
MYR
Nonstop1h 35m
Allegiant Air
Sun 7/266:34 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/7$138
This Cheapflightsfares deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/43:10 pm
MDT
-
MYR
Nonstop1h 35m
Allegiant Air
Sat 7/115:35 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/4$139
This Cheapflightsfares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:38 pm
MDT
-
MYR
Nonstop1h 34m
Allegiant Air
Thu 9/175:02 pm
MYR
-
MDT
Nonstop1h 31m
Allegiant Air
Deal found 6/3$145
This Gotogate deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/54:09 pm
MDT
-
MYR
Nonstop1h 35m
Allegiant Air
Sun 7/126:34 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/7$146
This Gotogate deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/164:09 pm
MDT
-
MYR
Nonstop1h 35m
Allegiant Air
Sun 7/196:34 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/7$152
This Cheapflightsfares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/164:09 pm
MDT
-
MYR
Nonstop1h 35m
Allegiant Air
Thu 7/236:34 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/3$155
This Cheapflightsfares deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/94:09 pm
MDT
-
MYR
Nonstop1h 35m
Allegiant Air
Sun 7/126:34 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/4$157
This Cheapflightsfares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/124:09 pm
MDT
-
MYR
Nonstop1h 35m
Allegiant Air
Thu 7/166:34 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Deal found 6/3$159

Find flight deals from Harrisburg to South Carolina

Keep the following information in mind while searching for Harrisburg to South Carolina flight deals. Data was last updated June 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$102
(Cheapflightsfares)

One-way from

$62
(Kiwi.com)

Popular in

March

Cheapest in

July

Average price

$170
Provider with most accurate pricing for Harrisburg-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Harrisburg-Myrtle Beach Intl flights.
From Harrisburg to South Carolina
One-way flight from Harrisburg to South Carolina
Highest demand for flights based on searches. 17% potential increase in price ($55 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($14 potential savings vs. average RT price).
Average for round-trip flights in June 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
Use the filters below to find and compare flights from Harrisburg to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 7/4

6:18 pm-2:50 pm

1 stop20h 32m

Greenville

Fri 7/10

3:10 pm-9:35 am

1 stop18h 25m

$239

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Sat 7/18

6:22 pm-11:53 pm

1 stop5h 31m

Charleston

Wed 7/22

6:15 am-10:56 am

1 stop4h 41m

$275

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Wed 7/22

6:04 am-10:13 am

1 stop4h 09m

Charleston

Sat 7/25

5:00 pm-11:53 pm

1 stop6h 53m

$275

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Sat 7/4

2:11 pm-9:56 pm

1 stop7h 45m

Savannah/Hilton Head

Tue 7/7

7:15 pm-11:30 pm

1 stop4h 15m

$285

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Sat 7/4

6:22 pm-11:57 pm

1 stop5h 35m

Charleston

Sat 7/11

6:24 pm-11:53 pm

1 stop5h 29m

$285

HarrisburgSavannah

MDT - SAV

MDTSAV

Harrisburg

Sat 7/4

6:37 am-11:05 am

1 stop4h 28m

Savannah/Hilton Head

Tue 7/7

7:07 pm-11:53 pm

1 stop4h 46m

$285

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Fri 7/31

6:22 pm-12:26 am

1 stop6h 04m

Charleston

Wed 8/5

5:10 am-11:08 am

1 stop5h 58m

$324

HarrisburgCharleston

MDT - CHS

MDTCHS

Harrisburg

Sat 7/4

6:22 pm-11:57 pm

1 stop5h 35m

Charleston

Fri 7/10

5:10 am-10:56 am

1 stop5h 46m

$324

HarrisburgColumbia

MDT - CAE

MDTCAE

Harrisburg

Sat 6/27

6:22 pm-11:50 pm

1 stop5h 28m

Columbia Metropolitan

Fri 7/3

6:01 pm-11:55 pm

1 stop5h 54m

$324

HarrisburgColumbia

MDT - CAE

MDTCAE

Harrisburg

Fri 7/10

10:30 am-2:16 pm

1 stop3h 46m

Columbia Metropolitan

Mon 7/13

7:45 pm-11:30 pm

1 stop3h 45m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/3

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Harrisburg to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to South Carolina

What is the cheapest month to book a flight from Harrisburg to South Carolina?

Currently, July is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $56). Flying from Harrisburg to South Carolina in November is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Harrisburg to South Carolina?

How far ahead should I book a flight from Harrisburg to South Carolina?

To ensure you get the cheapest price possible for a flight from Harrisburg to South Carolina, you should look to book at least 39 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 8, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAllegiant Air from Harrisburg to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Overall

7.9

Crew

8.5

Comfort

7.8

Food

7.2

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Boarding

8.1

Overall

7.9

Crew

8.5

Comfort

7.8

Food

7.2

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Boarding

8.1

Overall

7.9

Crew

8.5

Comfort

7.8

Food

7.2

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Boarding

8.1

Overall

7.9

Crew

8.5

Comfort

7.8

Food

7.2

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Boarding

8.1

Overall

7.9

Crew

8.5

Comfort

7.8

Food

7.2

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Harrisburg to South Carolina?

    If you book a flight to South Carolina from Harrisburg, you will be flying from Harrisburg, which is the city’s only airport. Harrisburg (MDT) is located 8.5 mi from the center of Harrisburg.

  • How long is the flight from Harrisburg to South Carolina?

    Allegiant Air, Delta, and United Airlines can get you from Harrisburg to South Carolina in just under 5h 31m. Your travel time can differ by up to 15h 01m. The distance between Harrisburg and South Carolina is about 536 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Harrisburg to South Carolina?

  • Can I find deals for flights from Harrisburg to South Carolina that include hotel bookings?

    Yes. In addition to deals on Harrisburg to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to South Carolina.

  • Can I find deals for business class flights from Harrisburg to South Carolina?

    Yes. Cheapflights offers flight deals from Harrisburg to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to South Carolina?

    Currently, July is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $56). Flying from Harrisburg to South Carolina in November is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Harrisburg to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Harrisburg to South Carolina

Discover the top 4 airlines that operate flights from Harrisburg to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$108Average$163FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$193Average$363FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$228Average$384FlexibilityNo cancel feeOn-time71%
DeltaCheapest$247Average$346FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.