$66+ Cheap flights from Harrisburg (MDT) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/30. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — CHS
Sep 18 — Sep 251
Round-trip
1 adult, Economy
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Find cheap flights from Harrisburg to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Harrisburg to South CarolinaExplore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 19, 2026.
Explore the most affordable flight options available from Harrisburg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 19, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/302:26 pm -
Nonstop1h 36m
Thu 9/34:52 pm -
Nonstop1h 31m
Deal found 8/15![Allegiant Air logo]()
$117
This Cheapflightsfares deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/113:58 pm -
Nonstop1h 30m
Thu 10/156:54 pm -
Nonstop1h 36m
Deal found 8/17![Allegiant Air logo]()
$133
This Cheapflightsfares deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/62:28 pm -
Nonstop1h 34m
Thu 9/104:52 pm -
Nonstop1h 31m
Deal found 8/18![Allegiant Air logo]()
$142
This Cheapflightsfares deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/254:05 pm -
Nonstop1h 30m
Sun 11/16:28 pm -
Nonstop1h 36m
Deal found 8/17![Allegiant Air logo]()
$151
This Cheapflightsfares deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/132:28 pm -
Nonstop1h 34m
Thu 9/244:52 pm -
Nonstop1h 31m
Deal found 8/17![Allegiant Air logo]()
$157
This Cheapflightsfares deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/44:07 pm -
Nonstop1h 30m
Thu 10/86:54 pm -
Nonstop1h 36m
Deal found 8/18![Allegiant Air logo]()
$189
This Cheapflightsfares deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/132:28 pm -
Nonstop1h 34m
Sun 9/204:52 pm -
Nonstop1h 31m
Deal found 8/14![Allegiant Air logo]()
$194
This Cheapflightsfares deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:28 pm -
Nonstop1h 34m
Thu 9/174:52 pm -
Nonstop1h 31m
Deal found 8/16![Allegiant Air logo]()
$209
This Cheapflightsfares deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:05 pm -
Nonstop1h 30m
Sun 10/256:25 pm -
Nonstop1h 36m
Deal found 8/17![Allegiant Air logo]()
$217
This Cheapflightsfares deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:26 pm -
Nonstop1h 36m
Sun 8/304:52 pm -
Nonstop1h 33m
Deal found 8/18![Allegiant Air logo]()
$231
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:43 am -
1 stop5h 50m
Sat 10/246:00 am -
1 stop4h 17m
Deal found 8/14![American Airlines logo]()
$285
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:52 pm -
1 stop4h 43m
Sat 9/121:06 pm -
1 stop7h 52m
Deal found 8/18![United Airlines logo]()
$295
Best flights from Harrisburg to South CarolinaDiscover carefully curated flight deals from Harrisburg to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 19, 2026.
Discover carefully curated flight deals from Harrisburg to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 19, 2026.
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:15 pm -
1 stop4h 31m
Tue 10/67:18 pm -
1 stop4h 08m
Deal found 8/17![American Airlines logo]()
$302
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:24 pm -
1 stop4h 35m
Sat 9/56:00 am -
1 stop5h 49m
Deal found 8/17![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:15 am -
1 stop4h 40m
Sun 9/69:53 am -
1 stop6h 59m
Deal found 8/18![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:22 pm -
1 stop5h 31m
Mon 11/167:50 pm -
1 stop4h 00m
Deal found 8/15![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:00 am -
1 stop3h 55m
Wed 12/1611:55 am -
1 stop6h 45m
Deal found 8/18![United Airlines logo]()
$365
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:06 pm -
1 stop4h 45m
Sun 10/117:00 am -
1 stop3h 54m
Deal found 8/15![Delta logo]()
$338
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:23 pm -
2 stops7h 21m
Sat 9/57:22 am -
1 stop3h 48m
Deal found 8/18![American Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/116:30 am -
1 stop8h 03m
Sun 2/1411:25 am -
1 stop7h 15m
Deal found 8/14![United Airlines logo]()
$368
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:09 pm -
1 stop5h 46m
Sat 9/196:00 am -
1 stop5h 44m
Deal found 8/14![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:15 pm -
1 stop4h 31m
Sun 9/278:41 pm -
1 stop3h 41m
Deal found 8/18![American Airlines logo]()
$397
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:08 pm -
1 stop6h 50m
Tue 10/276:20 am -
1 stop7h 04m
Deal found 8/18![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2211:00 am -
1 stop6h 53m
Mon 8/247:22 am -
1 stop6h 36m
Deal found 8/18![American Airlines logo]()
$402
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:52 pm -
1 stop4h 15m
Sat 9/122:15 pm -
1 stop6h 43m
Deal found 8/14![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:09 pm -
1 stop4h 46m
Sat 10/36:00 am -
1 stop5h 44m
Deal found 8/14![Delta logo]()
$370
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:30 am -
1 stop7h 10m
Wed 9/237:54 pm -
1 stop3h 36m
Deal found 8/16![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:06 pm -
1 stop5h 49m
Sun 10/117:26 pm -
1 stop4h 13m
Deal found 8/18![Delta logo]()
$413
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:52 pm -
1 stop4h 13m
Sun 9/610:00 am -
1 stop6h 52m
Deal found 8/18![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:25 pm -
1 stop5h 30m
Fri 10/307:26 pm -
1 stop4h 13m
Deal found 8/17![Delta logo]()
$413
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1911:17 am -
1 stop5h 24m
Wed 9/2310:16 am -
2 stops8h 46m
Deal found 8/16![American Airlines logo]()
$528
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:17 pm -
1 stop6h 50m
Wed 9/210:33 am -
1 stop6h 19m
Deal found 8/14![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:25 pm -
1 stop5h 22m
Sun 11/87:00 am -
1 stop3h 59m
Deal found 8/18![Delta logo]()
$419
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:08 pm -
1 stop7h 01m
Sat 10/2410:22 am -
1 stop6h 30m
Deal found 8/18![United Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:42 am -
2 stops6h 56m
Fri 10/305:00 am -
1 stop4h 11m
Deal found 8/17![American Airlines logo]()
$552
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:30 am -
1 stop5h 40m
Wed 9/231:06 pm -
1 stop7h 52m
Deal found 8/18![United Airlines logo]()
$414
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:18 pm -
2 stops8h 31m
Sun 10/116:03 pm -
1 stop6h 21m
Deal found 8/18![American Airlines logo]()
$552
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:25 pm -
1 stop5h 30m
Sun 11/85:25 am -
1 stop5h 34m
Deal found 8/15![Delta logo]()
$467
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:52 pm -
1 stop4h 18m
Sat 9/510:14 am -
1 stop3h 49m
Deal found 8/17![United Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:10 pm -
1 stop4h 16m
Sat 10/36:00 am -
1 stop5h 44m
Deal found 8/14![Delta logo]()
$472
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:15 am -
2 stops6h 04m
Sun 9/67:00 am -
1 stop4h 46m
Deal found 8/16![American Airlines logo]()
$577
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:13 am -
1 stop6h 07m
Sun 10/185:30 am -
1 stop5h 29m
Deal found 8/15![Delta logo]()
$519
Last-minute flights from Harrisburg to South CarolinaDiscover last-minute flight deals from Harrisburg to South Carolina. Data last updated August 19, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to South Carolina. Data last updated August 19, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/232:26 pm -
Nonstop1h 36m
Sun 8/304:52 pm -
Nonstop1h 33m
Deal found 8/18![Allegiant Air logo]()
$245
This Cheapflightsfares deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:26 pm -
Nonstop1h 36m
Sun 8/304:52 pm -
Nonstop1h 33m
Deal found 8/18![Allegiant Air logo]()
$231
This Cheapflightsfares deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/302:26 pm -
Nonstop1h 36m
Thu 9/34:52 pm -
Nonstop1h 31m
Deal found 8/15![Allegiant Air logo]()
$117
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:57 am -
1 stop3h 22m
Wed 9/910:33 am -
1 stop6h 19m
Deal found 8/17![United Airlines logo]()
$314
This Cheapflightsfares deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:28 pm -
Nonstop1h 34m
Thu 9/174:52 pm -
Nonstop1h 31m
Deal found 8/16![Allegiant Air logo]()
$209
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:30 am -
1 stop7h 28m
Tue 9/88:55 am -
1 stop7h 57m
Deal found 8/18![United Airlines logo]()
$302
This Cheapflightsfares deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/62:28 pm -
Nonstop1h 34m
Thu 9/104:52 pm -
Nonstop1h 31m
Deal found 8/18![Allegiant Air logo]()
$142
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:52 pm -
1 stop4h 43m
Sat 9/121:06 pm -
1 stop7h 52m
Deal found 8/18![United Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:59 pm -
1 stop6h 05m
Sat 9/196:22 am -
1 stop3h 55m
Deal found 8/14![American Airlines logo]()
$307
This Cheapflightsfares deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/132:28 pm -
Nonstop1h 34m
Thu 9/244:52 pm -
Nonstop1h 31m
Deal found 8/17![Allegiant Air logo]()
$157
This Cheapflightsfares deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/132:28 pm -
Nonstop1h 34m
Sun 9/204:52 pm -
Nonstop1h 31m
Deal found 8/14![Allegiant Air logo]()
$194
This Cheapflightsfares deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:28 pm -
Nonstop1h 34m
Sun 9/204:52 pm -
Nonstop1h 31m
Deal found 8/15![Allegiant Air logo]()
$251
One-way flights from Harrisburg to South CarolinaSearch for one-way flight options from Harrisburg to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 19, 2026.
Search for one-way flight options from Harrisburg to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 19, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/302:26 pm -
Nonstop1h 36m
Deal found 8/15![Allegiant Air logo]()
$66
This Super.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/132:28 pm -
Nonstop1h 34m
Deal found 8/14![Allegiant Air logo]()
$74
This Super.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:26 pm -
Nonstop1h 36m
Deal found 8/14![Allegiant Air logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/84:39 pm -
Nonstop1h 30m
Deal found 8/17![Allegiant Air logo]()
$111
This Cheapflightsfares deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/202:28 pm -
Nonstop1h 34m
Deal found 8/14![Allegiant Air logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/185:14 pm -
2 stops39h 23m
Deal found 8/18![Multiple Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1510:02 pm -
2 stops36h 03m
Deal found 8/19![Multiple Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:56 am -
1 stop23h 09m
Deal found 8/14![Multiple Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1510:02 pm -
3 stops37h 13m
Deal found 8/16![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/113:58 pm -
2 stops40h 39m
Deal found 8/14![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:38 pm -
3 stops43h 38m
Deal found 8/15![Multiple Airlines logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:08 pm -
1 stop16h 30m
Deal found 8/16![Multiple Airlines logo]()
$235
Find flight deals from Harrisburg to South Carolina
Keep the following information in mind while searching for Harrisburg to South Carolina flight deals. Data was last updated August 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $117 (Cheapflightsfares) |
One-way from | $66 (Cheapflightsfares) |
Popular in | December |
Cheapest in | July |
Average price | $204 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 19, 2026.
Use the filters below to find and compare flights from Harrisburg to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HarrisburgCharleston
MDT Harrisburg - CHS Charleston
MDTCHS
Harrisburg
Thu 10/1
7:15 pm-11:46 pm
1 stop4h 31m
Charleston
Tue 10/6
7:18 pm-11:26 pm
1 stop4h 08m
$302
HarrisburgGreenville
MDT Harrisburg - GSP Greenville
MDTGSP
Harrisburg
Tue 9/1
6:24 pm-10:59 pm
1 stop4h 35m
Greenville
Sat 9/5
6:00 am-11:49 am
1 stop5h 49m
$329
HarrisburgColumbia
MDT Harrisburg - CAE Columbia Metropolitan
MDTCAE
Harrisburg
Wed 11/11
6:22 pm-11:53 pm
1 stop5h 31m
Columbia Metropolitan
Mon 11/16
7:50 pm-11:50 pm
1 stop4h 00m
$329
HarrisburgGreenville
MDT Harrisburg - GSP Greenville
MDTGSP
Harrisburg
Fri 10/9
6:06 pm-10:51 pm
1 stop4h 45m
Greenville
Sun 10/11
7:00 am-10:54 am
1 stop3h 54m
$338
HarrisburgSavannah
MDT Harrisburg - SAV Savannah/Hilton Head
MDTSAV
Harrisburg
Sat 9/12
6:09 pm-11:55 pm
1 stop5h 46m
Savannah/Hilton Head
Sat 9/19
6:00 am-11:44 am
1 stop5h 44m
$339
HarrisburgSavannah
MDT Harrisburg - SAV Savannah/Hilton Head
MDTSAV
Harrisburg
Thu 9/3
6:15 am-10:55 am
1 stop4h 40m
Savannah/Hilton Head
Sun 9/6
9:53 am-4:52 pm
1 stop6h 59m
$349
HarrisburgCharleston
MDT Harrisburg - CHS Charleston
MDTCHS
Harrisburg
Sat 12/12
6:00 am-9:55 am
1 stop3h 55m
Charleston
Wed 12/16
11:55 am-6:40 pm
1 stop6h 45m
$365
HarrisburgMyrtle Beach
MDT Harrisburg - MYR Myrtle Beach Intl
MDTMYR
Harrisburg
Thu 2/11
6:30 am-2:33 pm
1 stop8h 03m
Myrtle Beach Intl
Sun 2/14
11:25 am-6:40 pm
1 stop7h 15m
$368
HarrisburgGreenville
MDT Harrisburg - GSP Greenville
MDTGSP
Harrisburg
Sat 10/24
2:08 pm-8:58 pm
1 stop6h 50m
Greenville
Tue 10/27
6:20 am-1:24 pm
1 stop7h 04m
$369
HarrisburgColumbia
MDT Harrisburg - CAE Columbia Metropolitan
MDTCAE
Harrisburg
Wed 9/9
2:52 pm-7:07 pm
1 stop4h 15m
Columbia Metropolitan
Sat 9/12
2:15 pm-8:58 pm
1 stop6h 43m
$369
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Harrisburg to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Harrisburg with our price prediction graph.
MDT-CHS
MDT-GSP
MDT-SAV
MDT-CAE
MDT-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to South Carolina
MDT-USSC
MDT-CHS
MDT-GSP
MDT-SAV
MDT-CAE
What is the cheapest month to book a flight from Harrisburg to South Carolina?
Currently, June is the cheapest month in which you can book a flight from Harrisburg to South Carolina (average of $201). Flying from Harrisburg to South Carolina in March is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Harrisburg to South Carolina?
Airfare is below average for this route at the moment.
Harrisburg to South Carolina flights typically cost between $348 and $458 in October.The cheapest round-trip price found within the last 5 days was $285 on American Airlines (Oct 21-Oct 24).
How far ahead should I book a flight from Harrisburg to South Carolina?
To ensure you get the cheapest price possible for a flight from Harrisburg to South Carolina, you should look to book at least 68 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated August 19, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAllegiant Air from Harrisburg to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentSalvador,Aug 2026
PHL - DTW
Overall
7.8
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentSalvador,Aug 2026
PHL - DTW
Overall
7.8
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentSalvador,Aug 2026
PHL - DTW
Overall
7.8
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentSalvador,Aug 2026
PHL - DTW
Overall
7.8
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentSalvador,Aug 2026
PHL - DTW
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Harrisburg to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Harrisburg and South Carolina flights
Browse other Harrisburg and South Carolina flight options. Last updated on August 19, 2026.
Popular flight searches
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Harrisburg to South Carolina flights
Consider these flights traveling from Harrisburg to South Carolina.
Top 4 airlines flying from Harrisburg to South Carolina
Discover the top 4 airlines that operate flights from Harrisburg to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$122 | Average$175 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$228 | Average$382 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$228 | Average$412 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$260 | Average$365 | FlexibilityNo cancel fee | On-timeN/A |