Greenville

$226+ Cheap flights from Harrisburg to Greenville (MDT - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/19. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — GSP
Jul 6 — Jul 131
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Cheap flight deals from Harrisburg to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 1, 2025.

Round-trip from

$229
(Delta)

One-way from

$226
(United Airlines)

Popular in

December

Cheapest in

September

Average price

$294
From Harrisburg to Greenville
One-way flight from Harrisburg to Greenville
Highest demand for flights based on searches. 6% potential increase in price ($22 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Average for round-trip flights in July 2025

Find flight deals from Harrisburg to Greenville

Cheapest flights from Harrisburg to Greenville
Explore the most affordable flight options available from Harrisburg to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/146:29 pmMDT - GSP
1 stop5h 30mDelta
Tue 8/197:05 amGSP - MDT
1 stop4h 37mDelta
Deal found 6/30$229
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/96:15 amMDT - GSP
1 stop3h 37mUnited Airlines
Mon 7/147:45 pmGSP - MDT
1 stop3h 45mUnited Airlines
Deal found 7/1$277
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/301:00 pmMDT - GSP
1 stop5h 03mAmerican Airlines
Sat 8/25:30 amGSP - MDT
1 stop4h 17mAmerican Airlines
Deal found 6/29$290
This Mytrip deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/3011:49 amMDT - GSP
3 stops31h 37mMultiple Airlines
Wed 8/69:41 pmGSP - MDT
3 stops22h 48mMultiple Airlines
Deal found 6/30$656

Cheapflights Fare Finder

Customize your flight search to find flights from Harrisburg to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
Use the filters below to find and compare flights from Harrisburg to Greenville that are best for you.

Fly from

Harrisburg

Fly to

Greenville

Route

Depart

Return

Price

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Thu 8/14

6:29 pm-11:59 pm

1 stop5h 30m

Greenville

Tue 8/19

7:05 am-11:42 am

1 stop4h 37m

$229

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Wed 7/30

1:00 pm-6:03 pm

1 stop5h 03m

Greenville

Sat 8/2

5:30 am-9:47 am

1 stop4h 17m

$290

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 11/21

5:34 pm-2:10 pm

2 stops20h 36m

Greenville

Fri 11/28

12:37 pm-7:15 pm

1 stop6h 38m

$495

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Wed 7/30

11:49 am-7:26 pm

3 stops31h 37m

Greenville

Wed 8/6

9:41 pm-8:29 pm

3 stops22h 48m

$656

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 7/19

7:59 pm-11:44 pm

1 stop3h 45m

$226

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 7/19

4:36 pm-8:28 pm

3 stops27h 52m

$374

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 7/19

1:35 pm-7:55 pm

2 stops6h 20m

$489

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Best time to book a flight from Harrisburg to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Greenville

What is the cheapest month to book a flight from Harrisburg to Greenville?

Currently, January is the cheapest month in which you can book a flight from Harrisburg to Greenville (average of $329). Flying from Harrisburg to Greenville in March is currently the most expensive (average of $385). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to GSP?

Find hourly flight availability from Harrisburg to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 1, 2025.

It’s typically best to fly out from Harrisburg to Greenville in the morning. Doing so could potentially save you 36% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated July 1, 2025.
Read through reviews of airlines operating flights from Harrisburg to Greenville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines flying from Harrisburg to Greenville round-trip?

    Cheapflights users have booked flights from Harrisburg to Greenville round-trip from $229. Other airlines that can offer you cheap pricing are American Airlines, from $290, and United Airlines, from $495. You may be able to fly from Harrisburg to Greenville for 27% less than the average price by searching for these airlines.

  • Can I find deals for flights from Harrisburg to Greenville that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Greenville.

  • Can I find deals for business class flights from Harrisburg to Greenville?

    Yes. Cheapflights offers flight deals from Harrisburg to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Harrisburg to Greenville (average of $329). Flying from Harrisburg to Greenville in March is currently the most expensive (average of $385). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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Alternative routes for Harrisburg to Greenville

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Harrisburg to Greenville

Discover the top 3 airlines that operate flights from Harrisburg to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$308FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$298FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$233Average$338FlexibilityNo cancel feeOn-time69%

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