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South Carolina

$47+ Cheap flights from Florida Keys to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/29. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Florida Keys to South Carolina

Keep the following information in mind while searching for Florida Keys to South Carolina flight deals. Data was last updated July 31, 2025.

Round-trip from

$106
(Cheapflightsfares)

One-way from

$48
(Frontier)
From Florida Keys to South Carolina
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One-way flight from Florida Keys to South Carolina
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Find flight deals from Florida Keys to South Carolina

Cheapest flights from Florida Keys to South Carolina
Explore the most affordable flight options available from Florida Keys to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/3010:23 amMIA - CLT
Nonstop2h 15mSpirit Airlines
Sat 9/61:28 pmCLT - MIA
Nonstop2h 15mSpirit Airlines
Deal found 7/29$106
This Frontier deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1512:07 pmMIA - CLT
Nonstop2h 17mFrontier
Sun 8/179:12 amCLT - MIA
Nonstop2h 23mFrontier
Deal found 7/31$107
This FlightHub deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/298:45 amMIA - CLT
Nonstop2h 17mMultiple Airlines
Mon 9/11:43 pmCLT - MIA
Nonstop2h 05mMultiple Airlines
Deal found 7/29$109
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1012:00 pmMIA - CHS
1 stop6h 57mDelta
Wed 9/1710:21 amCHS - MIA
1 stop4h 56mDelta
Deal found 7/31$139
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1310:26 pmMIA - SAV
Nonstop1h 33mAmerican Airlines
Sat 9/206:00 amSAV - MIA
Nonstop1h 32mAmerican Airlines
Deal found 7/30$159
This Booking.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/149:59 amMIA - MYR
1 stop8h 36mSpirit Airlines
Mon 8/181:15 pmMYR - MIA
1 stop5h 37mSpirit Airlines
Deal found 7/30$162
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/238:26 amMIA - CHS
Nonstop1h 43mAmerican Airlines
Sat 8/3010:56 amCHS - MIA
Nonstop1h 44mAmerican Airlines
Deal found 7/30$174
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:00 amMIA - SAV
1 stop5h 08mDelta
Sat 10/45:05 pmSAV - MIA
1 stop4h 18mDelta
Deal found 7/29$179
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/171:30 pmMIA - CHS
1 stop6h 25mSouthwest
Tue 1/139:05 amCHS - MIA
1 stop9h 30mSouthwest
Deal found 7/30$187
This FlightHub deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/912:20 pmMIA - MYR
1 stop26h 35mFrontier
Thu 8/143:55 pmMYR - MIA
1 stop19h 25mFrontier
Deal found 7/29$195
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/278:05 amMIA - SAV
1 stop6h 30mSouthwest
Tue 9/301:00 pmSAV - MIA
1 stop8h 15mSouthwest
Deal found 7/29$196
This Frontier deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/319:42 pmMIA - CHS
1 stop10h 24mFrontier
Mon 8/49:05 amCHS - MIA
1 stop11h 33mFrontier
Deal found 7/31$198

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florida Keys to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Florida Keys to South Carolina that are best for you.

Fly from

Florida Keys

Fly to

South Carolina

Route

Depart

Return

Price

MiamiCharlotte

MIA - CLT

MIACLT

Miami

Sat 8/30

10:23 am-12:38 pm

Nonstop2h 15m

Charlotte Douglas

Sat 9/6

1:28 pm-3:43 pm

Nonstop2h 15m

$106

MiamiCharlotte

MIA - CLT

MIACLT

Miami

Fri 8/15

12:07 pm-2:24 pm

Nonstop2h 17m

Charlotte Douglas

Sun 8/17

9:12 am-11:35 am

Nonstop2h 23m

$107

MiamiCharlotte

MIA - CLT

MIACLT

Miami

Fri 8/29

8:45 am-11:02 am

Nonstop2h 17m

Charlotte Douglas

Mon 9/1

1:43 pm-3:48 pm

Nonstop2h 05m

$109

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 9/10

12:00 pm-6:57 pm

1 stop6h 57m

Charleston

Wed 9/17

10:21 am-3:17 pm

1 stop4h 56m

$139

MiamiSavannah

MIA - SAV

MIASAV

Miami

Sat 9/13

10:26 pm-11:59 pm

Nonstop1h 33m

Savannah/Hilton Head

Sat 9/20

6:00 am-7:32 am

Nonstop1h 32m

$159

MiamiMyrtle Beach

MIA - MYR

MIAMYR

Miami

Thu 8/14

9:59 am-6:35 pm

1 stop8h 36m

Myrtle Beach Intl

Mon 8/18

1:15 pm-6:52 pm

1 stop5h 37m

$162

MiamiCharleston

MIA - CHS

MIACHS

Miami

Sat 8/23

8:26 am-10:09 am

Nonstop1h 43m

Charleston

Sat 8/30

10:56 am-12:40 pm

Nonstop1h 44m

$174

MiamiSavannah

MIA - SAV

MIASAV

Miami

Tue 9/30

6:00 am-11:08 am

1 stop5h 08m

Savannah/Hilton Head

Sat 10/4

5:05 pm-9:23 pm

1 stop4h 18m

$179

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 12/17

1:30 pm-7:55 pm

1 stop6h 25m

Charleston

Tue 1/13

9:05 am-6:35 pm

1 stop9h 30m

$187

MiamiSavannah

MIA - SAV

MIASAV

Miami

Sat 9/27

8:05 am-2:35 pm

1 stop6h 30m

Savannah/Hilton Head

Tue 9/30

1:00 pm-9:15 pm

1 stop8h 15m

$196

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 60 results
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Best time to book a flight from Florida Keys to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to South Carolina

What is the cheapest time of day to fly from EOA to SC?

Find hourly flight availability from Florida Keys to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Florida Keys to South Carolina as you normally would.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 31, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and Breeze Airways from Florida Keys to South Carolina to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,981 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Breeze Airways
8.0
Very good
191 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,900 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Florida Keys to South Carolina one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $48. However, be on the lookout for offers from Spirit Airlines and Southwest, as they are both options that can get you from Florida Keys to South Carolina for a low price.

  • Can I find deals for flights from Florida Keys to South Carolina that include hotel bookings?

    Yes. In addition to deals on Florida Keys to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to South Carolina.

  • Can I find deals for business class flights from Florida Keys to South Carolina?

    Yes. Cheapflights offers flight deals from Florida Keys to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florida Keys to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Florida Keys to South Carolina (average of $217). Flying from Florida Keys to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Florida Keys to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Florida Keys to South Carolina

Discover the top 2 airlines that operate flights from Florida Keys to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$313FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$323Average$615FlexibilityNo cancel feeOn-time71%

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