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South Carolina

$56+ Cheap flights from Florida Keys to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/1. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Florida Keys to South Carolina

Keep the following information in mind while searching for Florida Keys to South Carolina flight deals. Data was last updated junio 12, 2025.

Round-trip from

$111
(Cheapflightsfares)

One-way from

$56
(Kiwi.com)
From Florida Keys to South Carolina
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One-way flight from Florida Keys to South Carolina
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Find flight deals from Florida Keys to South Carolina

Cheapest flights from Florida Keys to South Carolina
Explore the most affordable flight options available from Florida Keys to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/276:00 amMIA - CLT
Nonstop2h 09mSpirit Airlines
lun. 6/309:32 pmCLT - MIA
Nonstop2h 10mSpirit Airlines
Deal found 6/10$111
This Cheapflightsfares deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/36:00 amMIA - CLT
Nonstop2h 17mFrontier
dom. 7/69:13 amCLT - MIA
Nonstop2h 11mFrontier
Deal found 6/12$125
This Cheapflightsfares deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/206:00 amMIA - CLT
Nonstop2h 09mMultiple Airlines
dom. 6/229:07 amCLT - MIA
Nonstop2h 14mMultiple Airlines
Deal found 6/12$135
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/206:05 amMIA - GSP
1 stop10h 25mSouthwest
mié. 10/19:30 amGSP - MIA
1 stop7h 10mSouthwest
Deal found 6/12$150
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/88:26 amMIA - CHS
Nonstop1h 43mAmerican Airlines
mié. 8/2710:56 amCHS - MIA
Nonstop1h 44mAmerican Airlines
Deal found 6/11$159
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/85:30 amMIA - CLT
1 stop5h 27mDelta
lun. 8/115:35 amCLT - MIA
1 stop3h 48mDelta
Deal found 6/10$179
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/65:30 amMIA - CAE
1 stop3h 41mDelta
mié. 9/35:40 amCAE - MIA
1 stop5h 12mDelta
Deal found 6/11$179
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/32:45 pmMIA - CHS
1 stop4h 12mDelta
lun. 9/85:15 amCHS - MIA
1 stop4h 08mDelta
Deal found 6/11$179
This Cheapflightsfares deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/47:00 amMIA - MYR
1 stop6h 47mSpirit Airlines
dom. 9/712:18 pmMYR - MIA
1 stop6h 35mSpirit Airlines
Deal found 6/9$182
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/912:00 pmMIA - CHS
1 stop5h 50mSouthwest
mar. 7/157:15 amCHS - MIA
1 stop9h 05mSouthwest
Deal found 6/9$213
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/85:18 amMIA - CLT
Nonstop2h 08mAmerican Airlines
mar. 7/1510:29 pmCLT - MIA
Nonstop2h 08mAmerican Airlines
Deal found 6/11$229
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/217:00 amMIA - SAV
1 stop7h 16mMultiple Airlines
mar. 8/261:13 pmSAV - MIA
1 stop22h 59mMultiple Airlines
Deal found 6/10$231

Cheapflights Fare Finder

Customize your flight search to find flights from Florida Keys to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Florida Keys to South Carolina that are best for you.

Fly from

Florida Keys

Fly to

South Carolina

Route

Depart

Return

Price

MiamiCharlotte

MIA - CLT

MIACLT

Miami

vie. 6/27

6:00 am-8:09 am

Nonstop2h 09m

Charlotte Douglas

lun. 6/30

9:32 pm-11:42 pm

Nonstop2h 10m

$111

MiamiCharlotte

MIA - CLT

MIACLT

Miami

jue. 7/3

6:00 am-8:17 am

Nonstop2h 17m

Charlotte Douglas

dom. 7/6

9:13 am-11:24 am

Nonstop2h 11m

$125

MiamiCharlotte

MIA - CLT

MIACLT

Miami

vie. 6/20

6:00 am-8:09 am

Nonstop2h 09m

Charlotte Douglas

dom. 6/22

9:07 am-11:21 am

Nonstop2h 14m

$135

MiamiCharleston

MIA - CHS

MIACHS

Miami

vie. 8/8

8:26 am-10:09 am

Nonstop1h 43m

Charleston

mié. 8/27

10:56 am-12:40 pm

Nonstop1h 44m

$159

MiamiCharlotte

MIA - CLT

MIACLT

Miami

vie. 8/8

5:30 am-10:57 am

1 stop5h 27m

Charlotte Douglas

lun. 8/11

5:35 am-9:23 am

1 stop3h 48m

$179

MiamiColumbia

MIA - CAE

MIACAE

Miami

mié. 8/6

5:30 am-9:11 am

1 stop3h 41m

Columbia Metropolitan

mié. 9/3

5:40 am-10:52 am

1 stop5h 12m

$179

MiamiCharleston

MIA - CHS

MIACHS

Miami

mié. 9/3

2:45 pm-6:57 pm

1 stop4h 12m

Charleston

lun. 9/8

5:15 am-9:23 am

1 stop4h 08m

$179

MiamiMyrtle Beach

MIA - MYR

MIAMYR

Miami

jue. 9/4

7:00 am-1:47 pm

1 stop6h 47m

Myrtle Beach Intl

dom. 9/7

12:18 pm-6:53 pm

1 stop6h 35m

$182

MiamiCharleston

MIA - CHS

MIACHS

Miami

mié. 7/9

12:00 pm-5:50 pm

1 stop5h 50m

Charleston

mar. 7/15

7:15 am-4:20 pm

1 stop9h 05m

$213

MiamiCharlotte

MIA - CLT

MIACLT

Miami

mar. 7/8

5:18 am-7:26 am

Nonstop2h 08m

Charlotte Douglas

mar. 7/15

10:29 pm-12:37 am

Nonstop2h 08m

$229

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 60 results
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Best time to book a flight from Florida Keys to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to South Carolina

What is the cheapest time of day to fly from EOA to SC?

Find hourly flight availability from Florida Keys to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Florida Keys to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated junio 12, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest and Delta from Florida Keys to South Carolina to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Overall

8.0

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Overall

8.0

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,287 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Overall

8.0

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,946 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Overall

8.0

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,790 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Overall

8.0

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
JetBlue
7.3
Good
2,925 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Overall

8.0

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Florida Keys to South Carolina one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $56. However, be on the lookout for offers from Frontier and Delta, as they are both options that can get you from Florida Keys to South Carolina for a low price.

  • Can I find deals for flights from Florida Keys to South Carolina that include hotel bookings?

    Yes. In addition to deals on Florida Keys to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to South Carolina.

  • Can I find deals for business class flights from Florida Keys to South Carolina?

    Yes. Cheapflights offers flight deals from Florida Keys to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florida Keys to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Florida Keys to South Carolina (average of $217). Flying from Florida Keys to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Florida Keys to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Florida Keys to South Carolina

Discover the top airline that operate flights from Florida Keys to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$293Average$635FlexibilityNo cancel feeOn-time71%

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