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South America

$457+ Cheap flights from Santa Fe (SAF) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — BOG
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
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Cheap flight deals from Santa Fe to South America

Cheapest flights from Santa Fe to South America
Explore the most affordable flight options available from Santa Fe to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/185:53 pm
SAF
-
LIM
2 stops28h 02m
United Airlines
Tue 3/241:10 am
LIM
-
SAF
2 stops32h 58m
United Airlines
Deal found 2/1$721
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:01 pm
SAF
-
LIM
2 stops28h 54m
United Airlines
Mon 11/21:50 am
LIM
-
SAF
2 stops17h 16m
United Airlines
Deal found 2/2$758
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:15 am
SAF
-
LIM
2 stops15h 05m
American Airlines
Thu 3/2611:40 pm
LIM
-
SAF
2 stops17h 05m
American Airlines
Deal found 2/2$784
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:15 am
SAF
-
SCL
1 stop21h 50m
American Airlines
Tue 3/1010:15 pm
SCL
-
SAF
1 stop20h 30m
American Airlines
Deal found 2/1$854
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/31:23 pm
SAF
-
SCL
2 stops15h 27m
United Airlines
Tue 3/109:45 pm
SCL
-
SAF
2 stops20h 00m
United Airlines
Deal found 2/1$863
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:15 am
SAF
-
SCL
2 stops22h 50m
American Airlines
Sun 4/268:35 pm
SCL
-
SAF
2 stops26h 32m
American Airlines
Deal found 2/1$951
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:49 pm
SAF
-
LIM
2 stops28h 11m
United Airlines
Sat 4/1812:55 am
LIM
-
SAF
2 stops41h 18m
United Airlines
Deal found 2/2$1,142
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:15 am
SAF
-
LIM
2 stops15h 10m
American Airlines
Mon 7/2010:00 pm
LIM
-
SAF
2 stops22h 27m
American Airlines
Deal found 2/2$1,229
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:15 am
SAF
-
SCL
2 stops22h 35m
American Airlines
Sun 7/268:30 pm
SCL
-
SAF
2 stops17h 25m
American Airlines
Deal found 2/1$1,240
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/316:05 pm
SAF
-
SCL
2 stops58h 45m
United Airlines
Sat 2/1410:45 pm
SCL
-
SAF
2 stops20h 00m
United Airlines
Deal found 1/31$1,281
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/315:18 pm
SAF
-
SCL
2 stops34h 32m
American Airlines
Sat 2/1411:15 pm
SCL
-
SAF
1 stop17h 09m
American Airlines
Deal found 1/31$1,296
This Iberia deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:06 pm
SAF
-
SCL
2 stops52h 24m
Iberia
Tue 8/184:00 pm
SCL
-
SAF
2 stops43h 21m
Iberia
Deal found 2/1$2,627

Find flight deals from Santa Fe to South America

Keep the following information in mind while searching for Santa Fe to South America flight deals. Data was last updated February 3, 2026.

Round-trip from

$721
(United Airlines)

One-way from

$457
(American Airlines)
From Santa Fe to South America
Search Deals
One-way flight from Santa Fe to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Santa Fe to South America that are best for you.

Fly from

Santa Fe

Fly to

South America

Route

Depart

Return

Price

Santa FeLima

SAF - LIM

SAFLIM

Santa Fe

Wed 3/18

5:53 pm-10:55 pm

2 stops28h 02m

Lima J Chavez Intl

Tue 3/24

1:10 am-9:08 am

2 stops32h 58m

$721

Santa FeLima

SAF - LIM

SAFLIM

Santa Fe

Thu 3/19

6:15 am-10:20 pm

2 stops15h 05m

Lima J Chavez Intl

Thu 3/26

11:40 pm-3:45 pm

2 stops17h 05m

$784

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Tue 3/3

6:15 am-8:05 am

1 stop21h 50m

Santiago Arturo Merino Benitez

Tue 3/10

10:15 pm-3:45 pm

1 stop20h 30m

$854

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Tue 3/3

1:23 pm-8:50 am

2 stops15h 27m

Santiago Arturo Merino Benitez

Tue 3/10

9:45 pm-2:45 pm

2 stops20h 00m

$863

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Sun 4/19

6:15 am-7:05 am

2 stops22h 50m

Santiago Arturo Merino Benitez

Sun 4/26

8:35 pm-9:07 pm

2 stops26h 32m

$951

Santa FeLima

SAF - LIM

SAFLIM

Santa Fe

Thu 4/16

5:49 pm-11:00 pm

2 stops28h 11m

Lima J Chavez Intl

Sat 4/18

12:55 am-5:13 pm

2 stops41h 18m

$1,142

Santa FeLima

SAF - LIM

SAFLIM

Santa Fe

Wed 7/8

7:30 am-4:10 am

2 stops19h 40m

Lima J Chavez Intl

Mon 7/20

10:00 pm-7:27 pm

2 stops22h 27m

$1,229

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Wed 7/22

6:15 am-6:50 am

2 stops22h 35m

Santiago Arturo Merino Benitez

Sun 7/26

8:30 pm-11:55 am

2 stops17h 25m

$1,240

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Sat 4/18

12:36 pm-7:05 am

2 stops16h 29m

$457

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Best time to book a flight from Santa Fe to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Fe to South America

What is the cheapest month to book a flight from Santa Fe to South America?

Currently, June is the cheapest month in which you can book a flight from Santa Fe to South America (average of $471). Flying from Santa Fe to South America in December is currently the most expensive (average of $686). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santa Fe to South America?

    Most people fly from Santa Fe (SAF) if they book a flight from Santa Fe to South America. Santa Fe is conveniently located just 9.8 mi from Santa Fe’s city center.

  • How long is the flight from Santa Fe to South America?

    Airlines like United Airlines and American Airlines fly from Santa Fe to South America in about 15h 05m. The time it takes to get you to your destination can typically vary by up to 12h 57m. There are 3794 mi between Santa Fe and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Santa Fe to South America that include hotel bookings?

    Yes. In addition to deals on Santa Fe to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to South America.

  • Can I find deals for business class flights from Santa Fe to South America?

    Yes. Cheapflights offers flight deals from Santa Fe to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Fe to South America?

    Currently, June is the cheapest month in which you can book a flight from Santa Fe to South America (average of $471). Flying from Santa Fe to South America in December is currently the most expensive (average of $686). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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