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South America

$769+ Cheap flights from Santa Fe (SAF) to South America

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — BOG
Jan 8 — Jan 151
Thu 1/8
Thu 1/15
1 adult, Economy
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Cheap flight deals from Santa Fe to South America

Best flights from Santa Fe to South America
Discover carefully curated flight deals from Santa Fe to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 9, 2025.

This United Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2210:45 amSAF - SCL
2 stops18h 05mUnited Airlines
Mon 1/2610:45 pmSCL - SAF
2 stops26h 02mUnited Airlines
Deal found 12/6$769
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2310:28 amSAF - SCL
1 stop17h 47mAmerican Airlines
Fri 1/3010:30 pmSCL - SAF
1 stop15h 28mAmerican Airlines
Deal found 12/9$840
This American Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/316:25 amSAF - SCL
1 stop21h 50mAmerican Airlines
Sat 2/1411:15 pmSCL - SAF
1 stop20h 27mAmerican Airlines
Deal found 12/6$840

Find flight deals from Santa Fe to South America

Keep the following information in mind while searching for Santa Fe to South America flight deals. Data was last updated December 9, 2025.

Round-trip from

$769
(United Airlines)
From Santa Fe to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
Use the filters below to find and compare flights from Santa Fe to South America that are best for you.

Fly from

Santa Fe

Fly to

South America

Route

Depart

Return

Price

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Thu 1/22

10:45 am-8:50 am

2 stops18h 05m

Santiago Arturo Merino Benitez

Mon 1/26

10:45 pm-8:47 pm

2 stops26h 02m

$769

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Fri 1/23

10:28 am-8:15 am

1 stop17h 47m

Santiago Arturo Merino Benitez

Fri 1/30

10:30 pm-9:58 am

1 stop15h 28m

$840

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Sat 1/31

6:25 am-8:15 am

1 stop21h 50m

Santiago Arturo Merino Benitez

Sat 2/14

11:15 pm-3:42 pm

1 stop20h 27m

$840

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Fri 12/19

10:05 am-7:45 am

1 stop17h 40m

$818

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Fri 12/19

11:00 am-8:50 am

2 stops17h 50m

$865

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/7

Best time to book a flight from Santa Fe to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Fe to South America

What is the cheapest month to book a flight from Santa Fe to South America?

Currently, June is the cheapest month in which you can book a flight from Santa Fe to South America (average of $471). Flying from Santa Fe to South America in December is currently the most expensive (average of $686). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated December 9, 2025.
Read reviews from past customers who have flown American Airlines from Santa Fe to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,045 reviews

Boarding

7.5

Overall

7.2

Food

6.5

Entertainment

6.9

Crew

8.0

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,045 reviews
American Airlines
7.2
Good
11,045 reviews

Boarding

7.5

Overall

7.2

Food

6.5

Entertainment

6.9

Crew

8.0

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santa Fe to South America?

    Most people fly from Santa Fe (SAF) if they book a flight from Santa Fe to South America. Santa Fe is conveniently located just 9.8 mi from Santa Fe’s city center.

  • How long is the flight from Santa Fe to South America?

    Airlines like United Airlines and American Airlines fly from Santa Fe to South America in about 17h 47m. The time it takes to get you to your destination can typically vary by up to 18m. There are 5282 mi between Santa Fe and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Santa Fe to South America that include hotel bookings?

    Yes. In addition to deals on Santa Fe to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to South America.

  • Can I find deals for business class flights from Santa Fe to South America?

    Yes. Cheapflights offers flight deals from Santa Fe to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Fe to South America?

    Currently, June is the cheapest month in which you can book a flight from Santa Fe to South America (average of $471). Flying from Santa Fe to South America in December is currently the most expensive (average of $686). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Santa Fe to South America

Discover the top airline that operate flights from Santa Fe to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$647Average$1,037FlexibilityNo cancel feeOn-time71%

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