South America

$293+ Cheap flights from McAllen (MFE) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — BOG
Dec 6 — Dec 131
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Cheap flight deals from McAllen to South America

Keep the following information in mind while searching for McAllen to South America flight deals. Data was last updated November 6, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$480
(United Airlines)

One-way from

$293
(Mytrip)
Provider with most accurate pricing for McAllen Miller Intl-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for McAllen Miller Intl-Sao Paulo (SAO) flights.
From McAllen Miller Intl to South America
One-way flight from McAllen Miller Intl to South America

Find flight deals from McAllen to South America

Cheapest flights from McAllen to South America
Explore the most affordable flight options available from McAllen to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:25 amMFE - BOG
2 stops13h 55mDelta
Sun 12/73:55 pmBOG - MFE
2 stops21h 14mDelta
Deal found 11/5$675
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/132:06 pmMFE - BOG
1 stop7h 29mUnited Airlines
Mon 11/178:15 amBOG - MFE
1 stop14h 44mUnited Airlines
Deal found 11/5$683
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/135:25 amMFE - BOG
2 stops13h 05mDelta
Mon 11/173:55 pmBOG - MFE
2 stops21h 09mDelta
Deal found 11/6$688
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:42 pmMFE - BOG
2 stops22h 33mAmerican Airlines
Sun 12/711:55 pmBOG - MFE
1 stop11h 45mAmerican Airlines
Deal found 11/5$691
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:05 amMFE - BOG
2 stops14h 05mAmerican Airlines
Mon 11/1711:55 pmBOG - MFE
1 stop20h 10mAmerican Airlines
Deal found 11/5$704
This Mytrip deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/38:33 pmMFE - BOG
3 stops27h 39mMultiple Airlines
Sat 12/62:17 amBOG - MFE
2 stops34h 07mMultiple Airlines
Deal found 11/5$783
This United deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:00 amMFE - BOG
2 stops21h 00mMultiple Airlines
Sun 11/161:30 amBOG - MFE
1 stop13h 00mMultiple Airlines
Deal found 11/5$845
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:00 amMFE - EZE
1 stop21h 20mUnited Airlines
Sun 11/1611:55 pmEZE - MFE
1 stop23h 13mUnited Airlines
Deal found 11/5$1,216
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/812:31 pmMFE - EZE
2 stops17h 29mDelta
Sun 11/168:55 pmEZE - MFE
2 stops18h 09mDelta
Deal found 11/5$1,220
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:00 amMFE - CTG
2 stops17h 00mUnited Airlines
Sat 12/276:25 amCTG - MFE
2 stops18h 00mUnited Airlines
Deal found 11/5$1,232
This United deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:00 amMFE - EZE
3 stops43h 10mMultiple Airlines
Sun 11/166:15 amEZE - MFE
3 stops53h 39mMultiple Airlines
Deal found 11/5$1,286
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:00 pmMFE - EZE
1 stop33h 20mUnited Airlines
Sat 12/2711:55 pmEZE - MFE
1 stop19h 05mUnited Airlines
Deal found 11/4$1,535

Cheapflights Fare Finder

 
Customize your flight search to find flights from McAllen to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from McAllen to South America that are best for you.

Fly from

McAllen

Fly to

South America

Route

Depart

Return

Price

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Mon 1/19

5:25 pm-5:10 am

1 stop10h 45m

Bogotá El Dorado

Wed 2/25

8:15 am-7:50 pm

1 stop12h 35m

$463

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Mon 1/19

5:25 am-7:30 pm

2 stops13h 05m

Bogotá El Dorado

Wed 2/25

10:55 am-11:57 pm

2 stops14h 02m

$468

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Thu 4/30

5:15 am-7:20 pm

1 stop14h 05m

Bogotá El Dorado

Mon 5/4

8:30 am-9:07 am

1 stop24h 37m

$480

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Thu 4/30

5:25 pm-1:50 pm

2 stops20h 25m

Bogotá El Dorado

Mon 5/4

2:55 pm-12:23 pm

2 stops21h 28m

$488

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Mon 1/19

3:26 pm-2:15 pm

2 stops21h 49m

Bogotá El Dorado

Wed 2/25

11:55 pm-11:09 pm

1 stop24h 14m

$505

McAllenCartagena

MFE - CTG

MFECTG

McAllen Miller Intl

Mon 3/23

9:40 am-11:00 pm

2 stops13h 20m

Cartagena Rafael Nunez

Fri 3/27

5:55 pm-9:07 am

2 stops39h 12m

$542

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Thu 4/30

5:00 am-9:55 pm

1 stop16h 55m

Bogotá El Dorado

Mon 5/4

2:25 pm-1:56 pm

2 stops23h 31m

$640

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Wed 12/3

5:25 am-8:20 pm

2 stops13h 55m

Bogotá El Dorado

Sun 12/7

3:55 pm-12:09 pm

2 stops21h 14m

$675

McAllenCartagena

MFE - CTG

MFECTG

McAllen Miller Intl

Mon 3/23

7:36 am-12:00 pm

2 stops28h 24m

Cartagena Rafael Nunez

Fri 3/27

3:50 pm-6:25 pm

2 stops26h 35m

$756

McAllenBuenos Aires

MFE - EZE

MFEEZE

McAllen Miller Intl

Thu 4/23

12:48 pm-9:45 am

2 stops18h 57m

Buenos Aires Ministro Pistarini

Thu 4/30

8:10 pm-11:59 pm

2 stops29h 49m

$961

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/6

Showing 1-10 of 37 results
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Best time to book a flight from McAllen to South America

Have a flexible travel schedule? Discover the best time to fly to South America from McAllen with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from McAllen to South America

What is the cheapest month to book a flight from McAllen to South America?

Currently, February is the cheapest month in which you can book a flight from McAllen to South America (average of $441). Flying from McAllen to South America in December is currently the most expensive (average of $1,516). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFE to SA?

Find hourly flight availability from McAllen to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

It’s optimal to fly from McAllen to South America in the evening. By choosing this option you can save up to 34% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated November 6, 2025.
Get a feel of what it's like to fly with United Airlines and American Airlines from McAllen to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.1

Entertainment

7.1

Overall

7.4

Boarding

7.7

Comfort

7.3

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Crew

8.1

Entertainment

7.1

Overall

7.4

Boarding

7.7

Comfort

7.3

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Crew

8.1

Entertainment

7.1

Overall

7.4

Boarding

7.7

Comfort

7.3

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from McAllen to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from McAllen to South America?

    Located just 2.0 mi from the city center, McAllen Miller Intl (MFE) is the airport most travelers will use when flying to South America from McAllen.

  • How long is the flight from McAllen to South America?

    Departing from McAllen to South America will take you 10h 45m. The distance from McAllen to South America is about 2175 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from McAllen to South America one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $349. However, be on the lookout for offers from United Airlines and Aeromexico, as they are both options that can get you from McAllen to South America for a low price.

  • What are the most popular routes from McAllen to South America?

  • Can I find deals for flights from McAllen to South America that include hotel bookings?

    Yes. In addition to deals on McAllen to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from McAllen to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from McAllen to South America.

  • Can I find deals for business class flights from McAllen to South America?

    Yes. Cheapflights offers flight deals from McAllen to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from McAllen to South America?

    Currently, February is the cheapest month in which you can book a flight from McAllen to South America (average of $441). Flying from McAllen to South America in December is currently the most expensive (average of $1,516). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for McAllen to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from McAllen to South America

Discover the top 2 airlines that operate flights from McAllen to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$429Average$860FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$443Average$692FlexibilityNo cancel feeOn-time71%

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