$211+ Cheap flights from Jacksonville (JAX) to South America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — BOG
Nov 30 — Dec 71
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Jacksonville to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Jacksonville to South America
Cheapest
Best
Last-minute
One-way
Cheapest flights from Jacksonville to South AmericaExplore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2026.
Explore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2026.
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:35 am -
1 stop5h 57m
Fri 12/44:37 pm -
2 stops17h 02m
Deal found 10/30![American Airlines logo]()
$473
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:22 pm -
2 stops19h 10m
Sun 12/64:37 pm -
1 stop7h 50m
Deal found 10/29![American Airlines logo]()
$497
This BusinessClass deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:15 pm -
2 stops21h 22m
Tue 12/82:36 pm -
1 stop8h 53m
Deal found 10/29![GOL logo]()
$507
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:33 pm -
1 stop19h 04m
Tue 12/84:37 pm -
1 stop6h 52m
Deal found 10/29![American Airlines logo]()
$540
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:24 pm -
2 stops18h 00m
Thu 12/107:00 am -
1 stop11h 36m
Deal found 10/29![American Airlines logo]()
$544
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:45 pm -
2 stops29h 25m
Thu 11/1910:40 am -
1 stop12h 35m
Deal found 10/28![United Airlines logo]()
$548
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:33 am -
1 stop6h 02m
Sat 11/144:37 pm -
1 stop7h 45m
Deal found 10/28![American Airlines logo]()
$551
This Avianca deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:05 am -
2 stops13h 30m
Sun 11/810:30 pm -
2 stops18h 25m
Deal found 10/29![Multiple Airlines logo]()
$553
This Avianca deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:15 pm -
1 stop12h 45m
Sun 11/88:00 pm -
1 stop18h 38m
Deal found 10/29![Multiple Airlines logo]()
$558
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am -
1 stop9h 34m
Mon 11/304:34 pm -
1 stop8h 06m
Deal found 10/27![American Airlines logo]()
$565
This FlightHub deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:09 pm -
1 stop17h 16m
Sat 11/144:40 pm -
1 stop16h 49m
Deal found 10/31![Multiple Airlines logo]()
$570
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:00 am -
1 stop9h 37m
Mon 12/214:48 pm -
1 stop16h 40m
Deal found 10/29![American Airlines logo]()
$573
Best flights from Jacksonville to South AmericaDiscover carefully curated flight deals from Jacksonville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 31, 2026.
Discover carefully curated flight deals from Jacksonville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 31, 2026.
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/281:00 pm -
1 stop26h 38m
Tue 2/22:35 pm -
1 stop8h 44m
Deal found 10/29![American Airlines logo]()
$481
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/57:00 am -
1 stop15h 10m
Mon 3/810:40 am -
2 stops28h 36m
Deal found 10/27![United Airlines logo]()
$503
This FlightHub deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/117:09 pm -
1 stop17h 16m
Mon 1/254:40 pm -
1 stop17h 52m
Deal found 10/29![Multiple Airlines logo]()
$570
This JetBlue deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:09 am -
1 stop5h 36m
Sat 12/51:50 pm -
1 stop6h 43m
Deal found 10/29![JetBlue logo]()
$628
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/257:34 am -
1 stop13h 51m
Sun 2/1412:55 am -
1 stop13h 52m
Deal found 10/30![Delta logo]()
$775
This LATAM Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/213:45 pm -
1 stop14h 15m
Tue 5/412:05 pm -
1 stop10h 57m
Deal found 10/29![LATAM Airlines logo]()
$802
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/217:30 am -
2 stops14h 40m
Tue 1/2610:40 am -
2 stops27h 17m
Deal found 10/30![United Airlines logo]()
$503
This KAYAK deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:26 pm -
2 stops27h 31m
Thu 12/3112:23 pm -
2 stops27h 59m
Deal found 10/30![Copa Airlines logo]()
$1,009
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:24 pm -
2 stops18h 00m
Thu 12/107:00 am -
1 stop11h 36m
Deal found 10/29![American Airlines logo]()
$544
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1211:30 am -
2 stops51h 20m
Tue 2/164:00 pm -
1 stop18h 21m
Deal found 10/30![United Airlines logo]()
$506
This Avianca deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/147:09 pm -
1 stop11h 26m
Fri 1/223:30 am -
2 stops14h 12m
Deal found 10/29![Multiple Airlines logo]()
$589
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:35 am -
1 stop5h 57m
Mon 11/302:35 pm -
1 stop10h 05m
Deal found 10/31![American Airlines logo]()
$565
This Avianca deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2110:15 am -
1 stop20h 20m
Tue 2/26:55 pm -
2 stops15h 37m
Deal found 10/27![Multiple Airlines logo]()
$589
This JetBlue deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:09 am -
1 stop5h 36m
Tue 12/151:50 pm -
1 stop6h 43m
Deal found 10/27![JetBlue logo]()
$653
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:00 am -
1 stop9h 37m
Mon 12/214:48 pm -
1 stop16h 40m
Deal found 10/29![American Airlines logo]()
$573
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:00 am -
1 stop15h 10m
Tue 11/1710:40 am -
1 stop12h 35m
Deal found 10/30![United Airlines logo]()
$589
This Avianca deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/309:55 am -
1 stop20h 40m
Wed 1/203:30 am -
2 stops14h 46m
Deal found 10/30![Multiple Airlines logo]()
$627
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/187:59 pm -
2 stops22h 53m
Tue 2/98:55 am -
2 stops24h 24m
Deal found 10/28![Delta logo]()
$779
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/308:24 pm -
2 stops18h 09m
Mon 12/77:00 am -
2 stops15h 55m
Deal found 10/28![American Airlines logo]()
$602
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:29 pm -
1 stop28h 41m
Tue 11/1710:40 am -
2 stops23h 51m
Deal found 10/28![United Airlines logo]()
$603
This Avianca deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/303:40 pm -
1 stop14h 55m
Mon 1/253:30 am -
2 stops14h 46m
Deal found 10/30![Multiple Airlines logo]()
$627
This BusinessClass deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1512:00 pm -
2 stops22h 25m
Wed 1/61:15 pm -
2 stops24h 57m
Deal found 10/26![GOL logo]()
$1,671
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/145:30 am -
2 stops13h 22m
Sat 1/238:55 am -
2 stops24h 24m
Deal found 10/29![Delta logo]()
$799
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/263:44 pm -
1 stop30h 26m
Tue 12/110:40 am -
1 stop12h 33m
Deal found 10/29![United Airlines logo]()
$620
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:15 pm -
1 stop27h 11m
Sat 11/286:00 am -
1 stop13h 44m
Deal found 10/26![American Airlines logo]()
$630
This Justfly.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:50 am -
2 stops28h 20m
Wed 12/25:20 pm -
1 stop17h 13m
Deal found 10/26![Multiple Airlines logo]()
$652
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:35 am -
1 stop10h 55m
Mon 12/213:55 pm -
1 stop8h 01m
Deal found 10/29![Delta logo]()
$805
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/286:23 pm -
2 stops20h 10m
Wed 12/167:00 am -
1 stop14h 10m
Deal found 10/27![American Airlines logo]()
$637
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am -
2 stops17h 00m
Mon 11/309:35 am -
2 stops37h 05m
Deal found 10/28![United Airlines logo]()
$647
This Expedia deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/107:10 am -
2 stops11h 35m
Fri 2/194:20 pm -
2 stops27h 59m
Deal found 10/27![Multiple Airlines logo]()
$654
Last-minute flights from Jacksonville to South AmericaDiscover last-minute flight deals from Jacksonville to South America. Data last updated October 31, 2026 and is based on user searches.
Discover last-minute flight deals from Jacksonville to South America. Data last updated October 31, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3011:32 am -
1 stop9h 43m
Mon 11/27:30 am -
1 stop12h 30m
Deal found 10/28![American Airlines logo]()
$589
This Avianca deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:05 am -
2 stops13h 30m
Sun 11/810:30 pm -
2 stops18h 25m
Deal found 10/29![Multiple Airlines logo]()
$553
This Avianca deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:15 pm -
1 stop12h 45m
Sun 11/88:00 pm -
1 stop18h 38m
Deal found 10/29![Multiple Airlines logo]()
$558
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:33 am -
1 stop6h 02m
Sat 11/144:37 pm -
1 stop7h 45m
Deal found 10/28![American Airlines logo]()
$551
This FlightHub deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:09 pm -
1 stop17h 16m
Sat 11/144:40 pm -
1 stop16h 49m
Deal found 10/31![Multiple Airlines logo]()
$570
This FlightHub deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:09 pm -
1 stop17h 16m
Sun 11/157:00 am -
1 stop31h 38m
Deal found 10/31![Multiple Airlines logo]()
$579
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:45 pm -
2 stops29h 25m
Thu 11/1910:40 am -
1 stop12h 35m
Deal found 10/28![United Airlines logo]()
$548
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:29 pm -
1 stop28h 41m
Tue 11/1710:40 am -
1 stop12h 35m
Deal found 10/28![United Airlines logo]()
$598
This Avianca deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:09 pm -
1 stop11h 26m
Thu 12/35:20 pm -
1 stop17h 13m
Deal found 10/26![Multiple Airlines logo]()
$589
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am -
1 stop9h 34m
Mon 11/304:34 pm -
1 stop8h 06m
Deal found 10/27![American Airlines logo]()
$565
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:35 am -
1 stop5h 57m
Fri 12/44:37 pm -
2 stops17h 02m
Deal found 10/30![American Airlines logo]()
$473
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:22 pm -
2 stops19h 10m
Sun 12/64:37 pm -
1 stop7h 50m
Deal found 10/29![American Airlines logo]()
$497
One-way flights from Jacksonville to South AmericaSearch for one-way flight options from Jacksonville to South America. Find affordable one-way fares based on user searches. Data last updated October 31, 2026.
Search for one-way flight options from Jacksonville to South America. Find affordable one-way fares based on user searches. Data last updated October 31, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:20 pm -
2 stops53h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:55 pm -
2 stops45h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$216
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/227:00 am -
1 stop14h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![American Airlines logo]()
$223
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/227:35 pm -
2 stops26h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![United Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/153:00 pm -
2 stops46h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$248
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/294:58 pm -
2 stops53h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![United Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:44 am -
2 stops33h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$252
This JetBlue deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:05 am -
1 stop9h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![JetBlue logo]()
$259
This Avianca deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/183:40 pm -
1 stop16h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$265
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:00 am -
1 stop15h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![United Airlines logo]()
$268
This JetBlue deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:05 am -
1 stop9h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![JetBlue logo]()
$272
This Avianca deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:09 pm -
1 stop12h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$284
Find flight deals from Jacksonville to South America
Keep the following information in mind while searching for Jacksonville to South America flight deals. Data was last updated October 31, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $473 (American Airlines) |
One-way from | $211 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Jacksonville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 31, 2026.
Use the filters below to find and compare flights from Jacksonville to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
JacksonvilleMedellín
JAX Jacksonville - MDE Medellín Jose Maria Cordova Intl
JAXMDE
Jacksonville
Mon 3/22
8:00 am-8:49 pm
2 stops13h 49m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$223
JacksonvilleMedellín
JAX Jacksonville - MDE Medellín Jose Maria Cordova Intl
JAXMDE
Jacksonville
Fri 1/29
7:00 am-10:10 pm
1 stop15h 10m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$223
JacksonvilleMedellín
JAX Jacksonville - MDE Medellín Jose Maria Cordova Intl
JAXMDE
Jacksonville
Mon 3/22
7:35 pm-9:10 pm
2 stops26h 35m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$229
JacksonvilleGuayaquil
JAX Jacksonville - GYE Guayaquil Jose Joaquin de Olmedo
JAXGYE
Jacksonville
Sun 11/15
3:00 pm-1:42 pm
2 stops46h 42m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$248
JacksonvilleGuayaquil
JAX Jacksonville - GYE Guayaquil Jose Joaquin de Olmedo
JAXGYE
Jacksonville
Wed 11/18
3:40 pm-8:00 am
1 stop16h 20m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$265
JacksonvilleGuayaquil
JAX Jacksonville - GYE Guayaquil Jose Joaquin de Olmedo
JAXGYE
Jacksonville
Sat 11/7
7:09 pm-8:00 am
1 stop12h 51m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$265
JacksonvilleMedellín
JAX Jacksonville - MDE Medellín Jose Maria Cordova Intl
JAXMDE
Jacksonville
Fri 11/6
7:00 am-10:10 pm
1 stop15h 10m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$268
JacksonvilleQuito
JAX Jacksonville - UIO Quito Mariscal Sucr
JAXUIO
Jacksonville
Mon 12/7
7:06 pm-6:35 am
1 stop11h 29m
Quito Mariscal Sucr
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$284
JacksonvilleLima
JAX Jacksonville - LIM Lima J Chavez Intl
JAXLIM
Jacksonville
Wed 12/2
3:39 pm-4:55 am
3 stops37h 16m
Lima J Chavez Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$290
JacksonvilleGuayaquil
JAX Jacksonville - GYE Guayaquil Jose Joaquin de Olmedo
JAXGYE
Jacksonville
Thu 11/19
9:08 pm-11:40 pm
3 stops50h 32m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$314
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Jacksonville to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Jacksonville with our price prediction graph.
JAX-MDE
JAX-GYE
JAX-BOG
JAX-UIO
JAX-CLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Jacksonville to South America
JAX-0SA
JAX-MDE
JAX-GYE
JAX-BOG
JAX-UIO
What is the cheapest month to book a flight from Jacksonville to South America?
Currently, April is the cheapest month in which you can book a flight from Jacksonville to South America (average of $627). Flying from Jacksonville to South America in December is currently the most expensive (average of $1,136). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Jacksonville to South America?
To ensure you get the cheapest price possible for a flight from Jacksonville to South America, you should look to book at least 27 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated October 31, 2026.
Get a feel of what it's like to fly with Delta,LATAM Airlines, andUnited Airlines from Jacksonville to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Overall
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Overall
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Overall
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Overall
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Overall
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Jacksonville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top countries
Top destinations
Alternative routes for Jacksonville to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Jacksonville to South America by cabin class
Find flights from Jacksonville to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Jacksonville and South America flights
Browse other Jacksonville and South America flight options. Last updated on October 31, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Jacksonville to South America flights
Consider these flights traveling from Jacksonville to South America.
Top 5 airlines flying from Jacksonville to South America
Discover the top 5 airlines that operate flights from Jacksonville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 31, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$154 | Average$367 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$383 | Average$1,017 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$392 | Average$674 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$432 | Average$1,168 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$590 | Average$741 | FlexibilityNo cancel fee | On-time81% |