$148+ Cheap flights from Jacksonville (JAX) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — BOG
Aug 3 — Aug 101
Round-trip
1 adult, Economy
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Find cheap flights from Jacksonville to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Jacksonville to South America
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Cheapest flights from Jacksonville to South AmericaExplore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 4, 2026.
Explore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 4, 2026.
This JetBlue deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Wed 9/212:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 6/30![JetBlue logo]()
$295
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
JAX
- CTG
2 stops9h 15m
American Airlines
Wed 9/21:35 pm
CTG
- JAX
1 stop9h 59m
American Airlines
Deal found 6/30![American Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/41:44 pm
JAX
- MDE
2 stops11h 04m
American Airlines
Fri 8/76:00 am
MDE
- JAX
2 stops16h 06m
American Airlines
Deal found 6/30![American Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:58 pm
JAX
- MDE
2 stops29h 12m
United Airlines
Wed 10/219:45 am
MDE
- JAX
1 stop12h 35m
United Airlines
Deal found 6/30![United Airlines logo]()
$345
This KAYAK deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:00 am
JAX
- MDE
1 stop15h 10m
Multiple Airlines
Wed 11/1110:40 am
MDE
- JAX
2 stops23h 51m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$351
This KAYAK deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:05 am
JAX
- CTG
1 stop5h 25m
JetBlue
Tue 10/2012:35 pm
CTG
- JAX
1 stop6h 17m
JetBlue
Deal found 7/4![JetBlue logo]()
$355
This Ovago deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:05 am
JAX
- CTG
1 stop5h 26m
JetBlue
Sat 11/71:40 pm
CTG
- JAX
1 stop6h 12m
JetBlue
Deal found 6/30![JetBlue logo]()
$356
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:14 pm
JAX
- CTG
2 stops18h 19m
American Airlines
Sat 11/72:34 pm
CTG
- JAX
2 stops21h 08m
American Airlines
Deal found 6/30![American Airlines logo]()
$362
This KAYAK deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Sat 8/2212:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/2![JetBlue logo]()
$366
This Ovago deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Thu 8/2012:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/2![JetBlue logo]()
$367
This JetBlue deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Sat 8/2212:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/1![JetBlue logo]()
$368
This Cheapflightsfares deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:19 am
JAX
- GYE
1 stop8h 55m
JetBlue
Thu 9/1712:30 pm
GYE
- JAX
1 stop8h 59m
JetBlue
Deal found 7/1![JetBlue logo]()
$393
Best flights from Jacksonville to South AmericaDiscover carefully curated flight deals from Jacksonville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 4, 2026.
Discover carefully curated flight deals from Jacksonville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 4, 2026.
This JetBlue deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Wed 9/212:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/3![JetBlue logo]()
$295
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
JAX
- CTG
1 stop9h 15m
American Airlines
Wed 9/21:35 pm
CTG
- JAX
1 stop9h 59m
American Airlines
Deal found 7/1![American Airlines logo]()
$295
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:45 pm
JAX
- MDE
2 stops29h 25m
United Airlines
Mon 9/219:45 am
MDE
- JAX
1 stop12h 35m
United Airlines
Deal found 7/4![United Airlines logo]()
$402
This Orbitz deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/167:10 am
JAX
- CTG
1 stop5h 25m
Multiple Airlines
Sat 8/222:30 pm
CTG
- JAX
1 stop18h 49m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$403
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:59 pm
JAX
- BOG
2 stops22h 51m
Delta
Mon 10/268:35 am
BOG
- JAX
2 stops14h 21m
Delta
Deal found 6/30![Delta logo]()
$599
This oojo deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:59 pm
JAX
- LIM
1 stop17h 01m
LATAM Airlines
Thu 9/1012:05 pm
LIM
- JAX
1 stop10h 54m
LATAM Airlines
Deal found 7/3![LATAM Airlines logo]()
$700
This Ovago deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Thu 8/2012:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/2![JetBlue logo]()
$367
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/234:45 pm
JAX
- MDE
2 stops29h 25m
United Airlines
Wed 8/269:45 am
MDE
- JAX
2 stops27h 19m
United Airlines
Deal found 7/3![United Airlines logo]()
$402
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:12 pm
JAX
- CTG
2 stops19h 23m
American Airlines
Sat 8/221:35 pm
CTG
- JAX
1 stop9h 59m
American Airlines
Deal found 6/29![American Airlines logo]()
$412
This Justfly.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:35 pm
JAX
- GRU
2 stops23h 15m
GOL
Fri 8/289:55 pm
GRU
- JAX
2 stops27h 39m
GOL
Deal found 6/30![GOL logo]()
$864
This JetBlue deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:19 am
JAX
- GYE
1 stop8h 55m
JetBlue
Thu 9/1712:30 pm
GYE
- JAX
1 stop8h 59m
JetBlue
Deal found 7/3![JetBlue logo]()
$401
This Avianca deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:00 pm
JAX
- GYE
1 stop13h 45m
Multiple Airlines
Mon 10/128:00 pm
GYE
- JAX
1 stop20h 57m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$463
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/611:40 am
JAX
- MDE
1 stop10h 30m
United Airlines
Wed 9/99:45 am
MDE
- JAX
1 stop12h 35m
United Airlines
Deal found 7/1![United Airlines logo]()
$430
This American Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:47 am
JAX
- CTG
1 stop5h 48m
American Airlines
Tue 10/201:35 pm
CTG
- JAX
2 stops18h 33m
American Airlines
Deal found 7/4![American Airlines logo]()
$443
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am
JAX
- MDE
1 stop15h 10m
United Airlines
Mon 11/1610:40 am
MDE
- JAX
2 stops27h 25m
United Airlines
Deal found 7/1![United Airlines logo]()
$447
This KAYAK deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:05 am
JAX
- GYE
1 stop9h 17m
JetBlue
Tue 10/131:30 pm
GYE
- JAX
1 stop24h 07m
JetBlue
Deal found 7/1![JetBlue logo]()
$475
This Avianca deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:58 pm
JAX
- BOG
1 stop13h 32m
Multiple Airlines
Mon 10/1911:15 pm
BOG
- JAX
1 stop14h 11m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$527
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:05 am
JAX
- CTG
2 stops16h 55m
United Airlines
Wed 9/23:05 pm
CTG
- JAX
2 stops22h 38m
United Airlines
Deal found 6/30![United Airlines logo]()
$462
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:00 am
JAX
- UIO
2 stops23h 43m
Delta
Wed 9/239:00 am
UIO
- JAX
2 stops13h 59m
Delta
Deal found 6/30![Delta logo]()
$619
This KAYAK deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:05 am
JAX
- EZE
2 stops16h 46m
Copa Airlines
Tue 8/258:59 am
EZE
- JAX
2 stops30h 05m
Copa Airlines
Deal found 6/30![Copa Airlines logo]()
$1,249
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:45 pm
JAX
- MDE
2 stops29h 25m
United Airlines
Tue 9/89:45 am
MDE
- JAX
2 stops27h 20m
United Airlines
Deal found 7/4![United Airlines logo]()
$467
This Avianca deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:33 pm
JAX
- BOG
2 stops9h 07m
Multiple Airlines
Mon 10/2611:15 pm
BOG
- JAX
1 stop14h 26m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$574
This LATAM Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/238:05 pm
JAX
- LIM
1 stop9h 55m
LATAM Airlines
Mon 8/3112:05 pm
LIM
- JAX
1 stop10h 50m
LATAM Airlines
Deal found 6/29![LATAM Airlines logo]()
$720
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:50 pm
JAX
- UIO
1 stop7h 09m
Delta
Thu 8/2012:59 am
UIO
- JAX
1 stop14h 30m
Delta
Deal found 7/2![Delta logo]()
$677
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:00 am
JAX
- BOG
1 stop6h 20m
American Airlines
Sat 8/86:30 am
BOG
- JAX
1 stop17h 04m
American Airlines
Deal found 7/2![American Airlines logo]()
$616
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:45 pm
JAX
- MDE
2 stops29h 25m
United Airlines
Wed 9/99:45 am
MDE
- JAX
1 stop12h 35m
United Airlines
Deal found 7/4![United Airlines logo]()
$467
This LATAM Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/83:53 pm
JAX
- LIM
1 stop13h 07m
LATAM Airlines
Thu 11/1211:40 pm
LIM
- JAX
1 stop10h 41m
LATAM Airlines
Deal found 7/3![LATAM Airlines logo]()
$727
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/299:20 am
JAX
- CTG
2 stops14h 40m
United Airlines
Wed 8/53:05 pm
CTG
- JAX
2 stops55h 17m
United Airlines
Deal found 7/1![United Airlines logo]()
$470
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:49 am
JAX
- GYE
2 stops13h 22m
American Airlines
Thu 9/176:00 am
GYE
- JAX
2 stops15h 30m
American Airlines
Deal found 6/30![American Airlines logo]()
$645
This oojo deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:59 pm
JAX
- LIM
1 stop11h 01m
LATAM Airlines
Tue 9/112:05 pm
LIM
- JAX
1 stop20h 32m
LATAM Airlines
Deal found 7/4![LATAM Airlines logo]()
$727
Last-minute flights from Jacksonville to South AmericaDiscover last-minute flight deals from Jacksonville to South America. Data last updated July 4, 2026 and is based on user searches.
Discover last-minute flight deals from Jacksonville to South America. Data last updated July 4, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:00 am
JAX
- CTG
1 stop7h 35m
American Airlines
Wed 8/51:35 pm
CTG
- JAX
2 stops18h 29m
American Airlines
Deal found 7/1![American Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/41:44 pm
JAX
- MDE
2 stops11h 04m
American Airlines
Fri 8/76:00 am
MDE
- JAX
2 stops16h 06m
American Airlines
Deal found 6/30![American Airlines logo]()
$338
This Ovago deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Thu 8/2012:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/2![JetBlue logo]()
$367
This JetBlue deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Sat 8/2212:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/1![JetBlue logo]()
$368
This Orbitz deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/167:10 am
JAX
- CTG
1 stop5h 25m
Multiple Airlines
Sat 8/222:30 pm
CTG
- JAX
1 stop18h 49m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$403
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:12 pm
JAX
- CTG
2 stops19h 23m
American Airlines
Sat 8/221:35 pm
CTG
- JAX
1 stop9h 59m
American Airlines
Deal found 6/29![American Airlines logo]()
$412
This KAYAK deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Sat 8/2212:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/2![JetBlue logo]()
$366
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:45 pm
JAX
- MDE
2 stops29h 25m
United Airlines
Mon 9/219:45 am
MDE
- JAX
2 stops36h 35m
United Airlines
Deal found 7/4![United Airlines logo]()
$417
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/234:45 pm
JAX
- MDE
2 stops29h 25m
United Airlines
Wed 8/269:45 am
MDE
- JAX
2 stops27h 19m
United Airlines
Deal found 7/3![United Airlines logo]()
$402
This KAYAK deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Mon 8/3112:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/3![JetBlue logo]()
$402
This JetBlue deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Wed 9/212:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 6/30![JetBlue logo]()
$295
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
JAX
- CTG
2 stops9h 15m
American Airlines
Wed 9/21:35 pm
CTG
- JAX
1 stop9h 59m
American Airlines
Deal found 6/30![American Airlines logo]()
$300
One-way flights from Jacksonville to South AmericaSearch for one-way flight options from Jacksonville to South America. Find affordable one-way fares based on user searches. Data last updated July 4, 2026.
Search for one-way flight options from Jacksonville to South America. Find affordable one-way fares based on user searches. Data last updated July 4, 2026.
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:00 am
JAX
- MDE
1 stop15h 10m
United Airlines
Deal found 6/30![United Airlines logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:30 am
JAX
- MDE
2 stops29h 15m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:49 am
JAX
- MDE
2 stops22h 26m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:05 pm
JAX
- MDE
3 stops49h 35m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$219
This Cheapflightsfares deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:05 am
JAX
- MDE
1 stop8h 25m
JetBlue
Deal found 7/2![JetBlue logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:30 am
JAX
- MDE
2 stops25h 25m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$233
This Avianca deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:36 pm
JAX
- GYE
1 stop15h 09m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$243
This Cheapflightsfares deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:44 pm
JAX
- MDE
1 stop17h 41m
JetBlue
Deal found 7/2![JetBlue logo]()
$243
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:45 pm
JAX
- BOG
1 stop12h 45m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$248
This Avianca deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:00 pm
JAX
- BOG
1 stop12h 15m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$264
This Trip.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/910:44 am
JAX
- LIM
2 stops15h 06m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$270
This BusinessClass deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:05 am
JAX
- GYE
1 stop29h 35m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$271
Find flight deals from Jacksonville to South America
Keep the following information in mind while searching for Jacksonville to South America flight deals. Data was last updated July 4, 2026.
Round-trip from | $295 (JetBlue) |
|---|---|
One-way from | $148 (United Airlines) |
Popular in | July |
Cheapest in | April |
Average price | $736 |
Cheapflights Fare Finder
Customize your flight search to find flights from Jacksonville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 4, 2026.
Use the filters below to find and compare flights from Jacksonville to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Sat 8/29
7:10 am-11:35 am
1 stop5h 25m
Cartagena Rafael Nunez
Wed 9/2
12:35 pm-7:57 pm
1 stop6h 22m
$295
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Sat 8/29
6:00 am-2:15 pm
1 stop9h 15m
Cartagena Rafael Nunez
Wed 9/2
1:35 pm-12:34 am
1 stop9h 59m
$295
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Thu 8/13
7:10 am-11:35 am
1 stop5h 25m
Cartagena Rafael Nunez
Thu 8/20
12:35 pm-7:57 pm
1 stop6h 22m
$367
JacksonvilleGuayaquil
JAX - GYE
JAXGYE
Jacksonville
Mon 9/14
7:19 am-3:14 pm
1 stop8h 55m
Guayaquil Jose Joaquin de Olmedo
Thu 9/17
12:30 pm-10:29 pm
1 stop8h 59m
$401
JacksonvilleMedellín
JAX - MDE
JAXMDE
Jacksonville
Fri 8/21
4:45 pm-9:10 pm
2 stops29h 25m
Medellín Jose Maria Cordova Intl
Mon 9/21
9:45 am-11:20 pm
1 stop12h 35m
$402
JacksonvilleMedellín
JAX - MDE
JAXMDE
Jacksonville
Sun 8/23
4:45 pm-9:10 pm
2 stops29h 25m
Medellín Jose Maria Cordova Intl
Wed 8/26
9:45 am-2:04 pm
2 stops27h 19m
$402
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Sun 8/16
7:10 am-11:35 am
1 stop5h 25m
Cartagena Rafael Nunez
Sat 8/22
2:30 pm-10:19 am
1 stop18h 49m
$403
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Sun 8/16
6:12 pm-12:35 pm
2 stops19h 23m
Cartagena Rafael Nunez
Sat 8/22
1:35 pm-12:34 am
1 stop9h 59m
$412
JacksonvilleMedellín
JAX - MDE
JAXMDE
Jacksonville
Sun 9/6
11:40 am-9:10 pm
1 stop10h 30m
Medellín Jose Maria Cordova Intl
Wed 9/9
9:45 am-11:20 pm
1 stop12h 35m
$430
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Tue 10/13
7:47 am-12:35 pm
1 stop5h 48m
Cartagena Rafael Nunez
Tue 10/20
1:35 pm-9:08 am
2 stops18h 33m
$443
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Jacksonville to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Jacksonville with our price prediction graph.
JAX-CTG
JAX-MDE
JAX-BOG
JAX-LIM
JAX-GRU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Jacksonville to South America
JAX-0SA
JAX-CTG
JAX-MDE
JAX-BOG
JAX-LIM
What is the cheapest month to book a flight from Jacksonville to South America?
Currently, February is the cheapest month in which you can book a flight from Jacksonville to South America (average of $154). Flying from Jacksonville to South America in January is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Jacksonville to South America?
To ensure you get the cheapest price possible for a flight from Jacksonville to South America, you should look to book at least 26 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated July 4, 2026.
Get a feel of what it's like to fly with Delta,LATAM Airlines, andUnited Airlines from Jacksonville to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Overall
7.8
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Overall
7.8
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Overall
7.8
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Overall
7.8
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Jacksonville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Jacksonville to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Jacksonville to South America by cabin class
Find flights from Jacksonville to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Jacksonville and South America flights
Browse other Jacksonville and South America flight options. Last updated on July 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Jacksonville to South America flights
Consider these flights traveling from Jacksonville to South America.
Top 4 airlines flying from Jacksonville to South America
Discover the top 4 airlines that operate flights from Jacksonville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$154 | Average$367 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$407 | Average$965 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$425 | Average$832 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$590 | Average$687 | FlexibilityNo cancel fee | On-time81% |