South Africa

$681+ Cheap flights from Knoxville (TYS) to South Africa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — JNB
Mar 7 — Mar 141
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Cheap flight deals from Knoxville to South Africa

Cheapest flights from Knoxville to South Africa
Explore the most affordable flight options available from Knoxville to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.

This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/225:47 pm
TYS
-
JNB
2 stops34h 38m
American Airlines
Sun 3/299:15 pm
JNB
-
TYS
2 stops26h 01m
American Airlines
Deal found 2/4$1,265
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/202:49 pm
TYS
-
JNB
2 stops33h 46m
American Airlines
Fri 2/277:35 pm
JNB
-
TYS
2 stops29h 38m
American Airlines
Deal found 2/3$1,442
This British Airways deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:10 am
TYS
-
JNB
2 stops42h 25m
British Airways
Sun 3/87:35 pm
JNB
-
TYS
2 stops30h 30m
British Airways
Deal found 2/4$1,456
This Gotogate deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:07 pm
TYS
-
CPT
2 stops41h 18m
Qatar Airways
Sun 12/612:35 pm
CPT
-
TYS
2 stops42h 22m
Qatar Airways
Deal found 2/3$1,489
This Gurufare deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:20 pm
TYS
-
CPT
2 stops41h 15m
Ethiopian Air
Sun 12/61:50 pm
CPT
-
TYS
3 stops31h 52m
Ethiopian Air
Deal found 2/3$1,700
This Booking.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:38 pm
TYS
-
JNB
2 stops30h 22m
Multiple Airlines
Fri 5/222:45 pm
JNB
-
TYS
2 stops28h 33m
Multiple Airlines
Deal found 2/3$1,787
This Qatar Airways deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Qatar Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/55:36 pm
TYS
-
JNB
2 stops38h 59m
Qatar Airways
Sun 2/812:45 pm
JNB
-
TYS
2 stops34h 01m
Qatar Airways
Deal found 2/1$1,809
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:47 am
TYS
-
CPT
1 stop27h 28m
Delta
Sun 12/69:30 pm
CPT
-
TYS
1 stop24h 35m
Delta
Deal found 2/3$1,876
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/164:00 pm
TYS
-
CPT
1 stop20h 15m
Delta
Tue 12/299:30 pm
CPT
-
TYS
1 stop31h 15m
Delta
Deal found 2/5$2,084
This Expedia deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/226:21 pm
TYS
-
JNB
2 stops32h 19m
Multiple Airlines
Sun 3/2910:50 pm
JNB
-
TYS
3 stops46h 19m
Multiple Airlines
Deal found 2/4$2,140
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/208:47 am
TYS
-
CPT
1 stop27h 28m
Delta
Thu 12/319:30 pm
CPT
-
TYS
1 stop31h 15m
Delta
Deal found 2/5$2,223
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/205:39 pm
TYS
-
CPT
2 stops31h 01m
United Airlines
Thu 12/319:30 am
CPT
-
TYS
2 stops45h 07m
United Airlines
Deal found 2/5$2,293

Find flight deals from Knoxville to South Africa

Keep the following information in mind while searching for Knoxville to South Africa flight deals. Data was last updated February 5, 2026.

Round-trip from

$1,265
(American Airlines)

One-way from

$681
(FlightHub)

Popular in

July

Cheapest in

November

Average price

$1,717
From Knoxville McGhee Tyson to South Africa
One-way flight from Knoxville McGhee Tyson to South Africa
Highest demand for flights based on searches. 3% potential increase in price ($69 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($54 potential savings vs. average RT price).
Average for round-trip flights in February 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Knoxville to South Africa that are best for you.

Fly from

Knoxville

Fly to

South Africa

Route

Depart

Return

Price

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sun 3/22

5:47 pm-10:25 am

2 stops34h 38m

Johannesburg OR Tambo

Sun 3/29

9:15 pm-5:16 pm

2 stops26h 01m

$1,265

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Fri 2/20

2:49 pm-7:35 am

2 stops33h 46m

Johannesburg OR Tambo

Fri 2/27

7:35 pm-6:13 pm

2 stops29h 38m

$1,442

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 3/4

6:10 am-7:35 am

2 stops42h 25m

Johannesburg OR Tambo

Sun 3/8

10:00 pm-9:05 pm

2 stops29h 05m

$1,456

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sun 3/22

5:10 pm-8:10 am

2 stops33h 00m

Johannesburg OR Tambo

Sun 3/29

9:55 pm-4:06 pm

1 stop24h 11m

$2,325

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sat 3/28

5:00 pm-9:25 am

2 stops34h 25m

Johannesburg OR Tambo

Sat 4/4

7:25 pm-3:48 pm

2 stops26h 23m

$2,402

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sun 5/17

8:48 pm-7:00 am

2 stops52h 12m

Johannesburg OR Tambo

Fri 5/22

2:30 pm-8:37 pm

3 stops36h 07m

$2,449

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sun 5/17

5:57 pm-7:40 pm

1 stop19h 43m

Johannesburg OR Tambo

Fri 5/22

9:55 pm-8:28 pm

1 stop28h 33m

$2,626

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sun 5/17

11:44 am-7:40 pm

2 stops25h 56m

Johannesburg OR Tambo

Fri 5/22

9:55 pm-6:48 pm

1 stop26h 53m

$2,631

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Tue 4/7

1:20 pm-3:20 pm

2 stops44h 00m

$681

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Tue 4/7

9:40 am-8:35 am

3 stops40h 55m

$1,613

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 11 results
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Best time to book a flight from Knoxville to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to South Africa
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Knoxville to South Africa?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to South Africa from Knoxville.

  • How long is the flight from Knoxville to South Africa?

    Airlines like American Airlines and British Airways fly from Knoxville to South Africa in about 34h 38m. The time it takes to get you to your destination can typically vary by up to 7h 47m. There are 8438 mi between Knoxville and South Africa. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Knoxville to South Africa that include hotel bookings?

    Yes. In addition to deals on Knoxville to South Africa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to South Africa.

  • Can I find deals for business class flights from Knoxville to South Africa?

    Yes. Cheapflights offers flight deals from Knoxville to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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