South Africa

$782+ Cheap flights from Knoxville (TYS) to South Africa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — JNB
feb. 28 — mar. 71
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Cheap flight deals from Knoxville to South Africa

Cheapest flights from Knoxville to South Africa
Explore the most affordable flight options available from Knoxville to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 29, 2026.

This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/195:06 pm
TYS
-
JNB
2 stops31h 54m
American Airlines
mié. 6/109:15 pm
JNB
-
TYS
2 stops26h 56m
American Airlines
Deal found 1/27$1,241
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/202:49 pm
TYS
-
JNB
2 stops33h 46m
American Airlines
vie. 2/277:35 pm
JNB
-
TYS
2 stops31h 49m
American Airlines
Deal found 1/28$1,265
This KAYAK deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/59:30 am
TYS
-
CPT
1 stop23h 40m
Multiple Airlines
sáb. 2/148:50 pm
CPT
-
TYS
2 stops44h 59m
Multiple Airlines
Deal found 1/27$1,390
This British Airways deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/55:15 pm
TYS
-
JNB
2 stops55h 20m
British Airways
dom. 2/810:00 pm
JNB
-
TYS
2 stops27h 46m
British Airways
Deal found 1/26$1,486
This KAYAK deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/611:07 am
TYS
-
CPT
2 stops23h 53m
Lufthansa
sáb. 2/148:50 pm
CPT
-
TYS
2 stops30h 47m
Lufthansa
Deal found 1/27$1,495
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/104:04 pm
TYS
-
CPT
2 stops34h 01m
American Airlines
mar. 3/316:50 pm
CPT
-
TYS
2 stops26h 58m
American Airlines
Deal found 1/27$1,500
This KAYAK deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/116:33 pm
TYS
-
JNB
2 stops32h 52m
British Airways
dom. 7/199:15 pm
JNB
-
TYS
2 stops26h 56m
British Airways
Deal found 1/26$1,599
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/152:49 pm
TYS
-
CPT
2 stops38h 11m
American Airlines
jue. 5/286:50 pm
CPT
-
TYS
2 stops29h 21m
American Airlines
Deal found 1/27$1,651
This Ovago deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/197:00 am
TYS
-
JNB
1 stop29h 30m
Lufthansa
mié. 6/1010:00 pm
JNB
-
TYS
2 stops25h 01m
Lufthansa
Deal found 1/27$1,656
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/103:13 pm
TYS
-
CPT
2 stops24h 42m
Delta
mar. 3/318:05 pm
CPT
-
TYS
1 stop19h 11m
Delta
Deal found 1/27$1,692
This Gurufare deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/197:00 am
TYS
-
JNB
3 stops38h 55m
Ethiopian Air
mié. 6/102:30 pm
JNB
-
TYS
3 stops29h 53m
Ethiopian Air
Deal found 1/27$1,716
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/134:15 pm
TYS
-
JNB
2 stops33h 20m
American Airlines
vie. 3/2010:00 pm
JNB
-
TYS
2 stops29h 05m
American Airlines
Deal found 1/27$1,740

Find flight deals from Knoxville to South Africa

Keep the following information in mind while searching for Knoxville to South Africa flight deals. Data was last updated enero 29, 2026.

Round-trip from

$1,241
(American Airlines)

One-way from

$782
(Kiwi.com)

Popular in

July

Cheapest in

November

Average price

$2,271
From Knoxville McGhee Tyson to South Africa
One-way flight from Knoxville McGhee Tyson to South Africa
Highest demand for flights based on searches. 3% potential increase in price ($69 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($54 potential savings vs. average RT price).
Average for round-trip flights in January 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 29, 2026.
Use the filters below to find and compare flights from Knoxville to South Africa that are best for you.

Fly from

Knoxville

Fly to

South Africa

Route

Depart

Return

Price

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

vie. 2/20

2:49 pm-7:35 am

2 stops33h 46m

Johannesburg OR Tambo

vie. 2/27

7:35 pm-8:24 pm

2 stops31h 49m

$1,265

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

mar. 3/10

4:04 pm-8:05 am

2 stops34h 01m

Cape Town Intl

mar. 3/31

6:50 pm-3:48 pm

2 stops26h 58m

$1,500

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

vie. 5/15

2:49 pm-11:00 am

2 stops38h 11m

Cape Town Intl

jue. 5/28

6:50 pm-6:11 pm

2 stops29h 21m

$1,651

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

mar. 5/19

7:00 am-6:30 pm

1 stop29h 30m

Johannesburg OR Tambo

mié. 6/10

10:00 pm-5:01 pm

2 stops25h 01m

$1,656

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

mar. 3/10

3:13 pm-9:55 pm

2 stops24h 42m

Cape Town Intl

mar. 3/31

8:05 pm-9:16 am

1 stop19h 11m

$1,692

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

mar. 5/19

7:00 am-3:55 am

3 stops38h 55m

Johannesburg OR Tambo

mié. 6/10

2:30 pm-2:23 pm

3 stops29h 53m

$1,716

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

vie. 3/13

4:15 pm-7:35 am

2 stops33h 20m

Johannesburg OR Tambo

vie. 3/20

10:00 pm-9:05 pm

2 stops29h 05m

$1,740

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

mar. 5/19

5:06 pm-11:00 am

2 stops35h 54m

Cape Town Intl

dom. 5/31

6:50 pm-6:11 pm

2 stops29h 21m

$1,786

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

mar. 5/19

1:52 pm-2:35 pm

2 stops42h 43m

Cape Town Intl

dom. 5/31

1:50 pm-5:01 pm

3 stops33h 11m

$1,830

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

mar. 5/19

7:00 am-10:50 pm

2 stops33h 50m

Cape Town Intl

dom. 5/31

8:00 pm-10:00 am

1 stop20h 00m

$1,888

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Showing 1-10 of 25 results
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Best time to book a flight from Knoxville to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to South Africa
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Knoxville to South Africa?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to South Africa from Knoxville.

  • How long is the flight from Knoxville to South Africa?

    Airlines like American Airlines, Lufthansa, and Delta fly from Knoxville to South Africa in about 24h 42m. The time it takes to get you to your destination can typically vary by up to 9h 04m. There are 8166 mi between Knoxville and South Africa. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Knoxville to South Africa that include hotel bookings?

    Yes. In addition to deals on Knoxville to South Africa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to South Africa.

  • Can I find deals for business class flights from Knoxville to South Africa?

    Yes. Cheapflights offers flight deals from Knoxville to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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