South Africa

$912+ Cheap flights from Knoxville (TYS) to South Africa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — JNB
Dec 4 — Dec 111
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Cheap flight deals from Knoxville to South Africa

Keep the following information in mind while searching for Knoxville to South Africa flight deals. Data was last updated November 4, 2025.

Round-trip from

$1,235
(American Airlines)

One-way from

$912
(American Airlines)

Popular in

July

Cheapest in

November

Average price

$1,088
From Knoxville McGhee Tyson to South Africa
One-way flight from Knoxville McGhee Tyson to South Africa
Highest demand for flights based on searches. 9% potential increase in price ($180 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($72 potential savings vs. average RT price).
Average for round-trip flights in November 2025

Find flight deals from Knoxville to South Africa

Cheapest flights from Knoxville to South Africa
Explore the most affordable flight options available from Knoxville to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2025.

This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:29 pmTYS - JNB
2 stops32h 06mAmerican Airlines
Mon 1/1210:00 pmJNB - TYS
2 stops29h 56mAmerican Airlines
Deal found 11/3$1,605
This Gurufare deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:45 amTYS - JNB
2 stops24h 20mEthiopian Air
Mon 1/122:30 pmJNB - TYS
3 stops31h 19mEthiopian Air
Deal found 11/3$1,819
This Booking.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:40 pmTYS - JNB
2 stops57h 45mBritish Airways
Fri 12/2610:00 pmJNB - TYS
2 stops29h 43mBritish Airways
Deal found 11/4$2,194
This Gurufare deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:45 amTYS - JNB
2 stops24h 20mEthiopian Air
Fri 12/262:30 pmJNB - TYS
3 stops31h 18mEthiopian Air
Deal found 11/4$2,631
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:45 amTYS - CPT
2 stops46h 15mUnited Airlines
Thu 12/258:50 pmCPT - TYS
2 stops28h 20mUnited Airlines
Deal found 11/3$2,773
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1812:50 pmTYS - CPT
2 stops26h 05mDelta
Thu 12/259:30 pmCPT - TYS
1 stop27h 44mDelta
Deal found 11/3$2,888
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/410:50 amTYS - JNB
2 stops24h 45mUnited Airlines
Fri 12/1210:00 pmJNB - TYS
2 stops23h 43mUnited Airlines
Deal found 11/3$3,156
This Gotogate deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:45 amTYS - JNB
2 stops24h 20mMultiple Airlines
Thu 12/251:45 pmJNB - TYS
2 stops41h 53mMultiple Airlines
Deal found 11/2$3,163
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/188:35 amTYS - JNB
1 stop27h 25mDelta
Thu 12/257:20 pmJNB - TYS
2 stops35h 13mDelta
Deal found 11/2$3,193
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:23 pmTYS - JNB
3 stops34h 42mMultiple Airlines
Fri 12/266:05 amJNB - TYS
3 stops43h 32mMultiple Airlines
Deal found 11/4$3,307
This oojo deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:45 amTYS - CPT
2 stops25h 00mEthiopian Air
Thu 12/253:25 pmCPT - TYS
3 stops54h 23mEthiopian Air
Deal found 11/3$3,553
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:35 amTYS - JNB
1 stop27h 25mDelta
Fri 12/2611:59 pmJNB - TYS
2 stops28h 16mDelta
Deal found 11/4$3,593

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Knoxville to South Africa that are best for you.

Fly from

Knoxville

Fly to

South Africa

Route

Depart

Return

Price

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 3/11

6:50 pm-10:25 am

2 stops33h 35m

Johannesburg OR Tambo

Wed 3/18

10:00 pm-9:29 pm

2 stops29h 29m

$1,235

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Thu 3/12

6:50 pm-10:25 am

2 stops33h 35m

Johannesburg OR Tambo

Mon 3/16

10:00 pm-8:39 pm

2 stops28h 39m

$1,235

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sun 2/15

5:57 pm-10:25 am

2 stops33h 28m

Johannesburg OR Tambo

Sun 2/22

7:35 pm-5:12 pm

2 stops28h 37m

$1,260

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Fri 3/6

4:56 pm-8:05 am

2 stops32h 09m

Cape Town Intl

Fri 3/13

6:55 pm-7:17 pm

2 stops30h 22m

$1,345

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Sat 3/21

8:31 pm-8:05 am

2 stops29h 34m

Cape Town Intl

Wed 3/25

8:35 pm-7:17 pm

2 stops28h 42m

$1,370

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Wed 2/18

2:21 pm-1:45 pm

2 stops40h 24m

Cape Town Intl

Tue 3/3

1:50 pm-3:15 pm

3 stops32h 25m

$1,445

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Wed 2/18

9:40 am-6:00 pm

2 stops25h 20m

Cape Town Intl

Tue 3/3

8:50 pm-7:29 pm

1 stop29h 39m

$1,506

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Fri 3/6

7:25 pm-4:10 pm

1 stop37h 45m

Cape Town Intl

Fri 3/13

9:30 am-8:54 pm

2 stops65h 24m

$1,560

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 3/11

2:30 pm-6:35 pm

2 stops22h 05m

Johannesburg OR Tambo

Wed 3/18

7:45 pm-5:25 pm

3 stops27h 40m

$1,585

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 12/31

4:29 pm-7:35 am

2 stops32h 06m

Johannesburg OR Tambo

Mon 1/12

10:00 pm-8:56 pm

2 stops29h 56m

$1,605

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 21 results
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Best time to book a flight from Knoxville to South Africa

Have a flexible travel schedule? Discover the best time to fly to South Africa from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to South Africa

What is the cheapest time of day to fly from TYS to ZA?

Find hourly flight availability from Knoxville to South Africa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 4, 2025.

When flying from Knoxville to South Africa, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 21% versus a flight in the afternoon.

Reviews of airlines servicing South Africa

Get insights into the airlines that provide service to South Africa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Africa. Reviews last updated November 4, 2025.
Read through reviews of airlines operating flights from Knoxville to South Africa, such as Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Knoxville to South Africa?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to South Africa from Knoxville.

  • How long is the flight from Knoxville to South Africa?

    Airlines like American Airlines, Ethiopian Air, and United Airlines fly from Knoxville to South Africa in about 22h 05m. The time it takes to get you to your destination can typically vary by up to 18h 19m. There are 8438 mi between Knoxville and South Africa. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Knoxville to South Africa one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $912. Delta flights start at $1,613 while deals on Air Canada start at $1,674 one-way.

  • Can I find deals for flights from Knoxville to South Africa that include hotel bookings?

    Yes. In addition to deals on Knoxville to South Africa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to South Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to South Africa.

  • Can I find deals for business class flights from Knoxville to South Africa?

    Yes. Cheapflights offers flight deals from Knoxville to South Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Knoxville to South Africa

Discover the top airline that operate flights from Knoxville to South Africa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$1,477Average$1,727FlexibilityNo cancel feeOn-timeN/A

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