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Africa

$394+ Cheap flights from Knoxville (TYS) to Africa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — JNB
May 18 — May 251
Mon 5/18
Mon 5/25
1 adult, Economy
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Cheap flight deals from Knoxville to Africa

Cheapest flights from Knoxville to Africa
Explore the most affordable flight options available from Knoxville to Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 18, 2026.

This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:00 pm
TYS
-
CMN
2 stops38h 30m
United Airlines
Wed 11/1112:15 pm
CMN
-
TYS
2 stops38h 50m
United Airlines
Deal found 4/15$718
This Air Canada deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:00 pm
TYS
-
CMN
2 stops38h 30m
Air Canada
Wed 11/1112:15 pm
CMN
-
TYS
2 stops17h 22m
Air Canada
Deal found 4/13$741
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:02 am
TYS
-
CMN
2 stops25h 18m
Delta
Thu 4/2310:25 am
CMN
-
TYS
2 stops27h 57m
Delta
Deal found 4/15$960
This Ovago deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:20 pm
TYS
-
CMN
2 stops30h 55m
Lufthansa
Wed 4/221:25 am
CMN
-
TYS
2 stops26h 09m
Lufthansa
Deal found 4/15$996
This KAYAK deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:30 pm
TYS
-
CMN
2 stops28h 00m
Lufthansa
Sat 5/309:00 am
CMN
-
TYS
2 stops19h 54m
Lufthansa
Deal found 4/17$1,042
This FlightHub deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:38 am
TYS
-
NBO
2 stops32h 27m
Qatar Airways
Mon 11/165:00 pm
NBO
-
TYS
2 stops36h 04m
Qatar Airways
Deal found 4/15$1,059
This oojo deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:47 am
TYS
-
NBO
2 stops37h 58m
Qatar Airways
Mon 9/286:00 pm
NBO
-
TYS
2 stops28h 05m
Qatar Airways
Deal found 4/14$1,061
This oojo deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:31 am
TYS
-
NBO
2 stops29h 19m
Qatar Airways
Mon 5/181:20 am
NBO
-
TYS
2 stops27h 37m
Qatar Airways
Deal found 4/14$1,065
This oojo deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:48 pm
TYS
-
NBO
2 stops44h 02m
Qatar Airways
Thu 5/71:20 am
NBO
-
TYS
2 stops27h 36m
Qatar Airways
Deal found 4/16$1,067
This FlightHub deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/111:45 pm
TYS
-
NBO
2 stops27h 20m
Qatar Airways
Sun 10/255:00 pm
NBO
-
TYS
2 stops29h 10m
Qatar Airways
Deal found 4/15$1,098
This Qatar Airways deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Qatar Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:47 am
TYS
-
NBO
2 stops37h 53m
Qatar Airways
Mon 10/58:10 am
NBO
-
TYS
2 stops42h 44m
Qatar Airways
Deal found 4/15$1,100
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:53 pm
TYS
-
CMN
2 stops32h 22m
United Airlines
Thu 4/239:00 am
CMN
-
TYS
3 stops18h 34m
United Airlines
Deal found 4/15$1,230

Find flight deals from Knoxville to Africa

Keep the following information in mind while searching for Knoxville to Africa flight deals. Data was last updated April 18, 2026.

Round-trip from

$1,042
(KAYAK)

One-way from

$394
(Justfly.com)
From Knoxville McGhee Tyson to Africa
Search Deals
One-way flight from Knoxville McGhee Tyson to Africa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
Use the filters below to find and compare flights from Knoxville to Africa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleCasablanca

TYS - CMN

TYSCMN

Knoxville McGhee Tyson

Tue 5/12

3:30 pm-12:30 am

2 stops28h 00m

Casablanca Mohamed V

Sat 5/30

9:00 am-11:54 pm

2 stops19h 54m

$1,042

KnoxvilleNairobi

TYS - NBO

TYSNBO

Knoxville McGhee Tyson

Thu 9/17

9:47 am-11:50 pm

2 stops31h 03m

Nairobi Jomo Kenyatta Intl

Mon 9/28

6:00 pm-3:05 pm

2 stops28h 05m

$1,061

KnoxvilleNairobi

TYS - NBO

TYSNBO

Knoxville McGhee Tyson

Thu 4/30

8:48 pm-11:50 pm

2 stops44h 02m

Nairobi Jomo Kenyatta Intl

Thu 5/7

1:20 am-9:56 pm

2 stops27h 36m

$1,067

KnoxvilleNairobi

TYS - NBO

TYSNBO

Knoxville McGhee Tyson

Thu 10/1

9:47 am-6:40 am

2 stops37h 53m

Nairobi Jomo Kenyatta Intl

Mon 10/5

8:10 am-3:10 pm

2 stops38h 00m

$1,100

KnoxvilleCasablanca

TYS - CMN

TYSCMN

Knoxville McGhee Tyson

Tue 5/26

7:33 pm-5:20 pm

2 stops16h 47m

Casablanca Mohamed V

Mon 7/13

6:20 pm-3:18 pm

2 stops25h 58m

$1,253

KnoxvilleCasablanca

TYS - CMN

TYSCMN

Knoxville McGhee Tyson

Fri 5/15

7:00 am-10:10 pm

2 stops34h 10m

Casablanca Mohamed V

Sat 5/23

2:35 pm-5:54 pm

2 stops32h 19m

$1,275

KnoxvilleNairobi

TYS - NBO

TYSNBO

Knoxville McGhee Tyson

Tue 5/26

11:29 am-7:20 am

2 stops36h 51m

Nairobi Jomo Kenyatta Intl

Tue 6/2

6:00 pm-9:59 pm

2 stops34h 59m

$1,379

KnoxvilleCasablanca

TYS - CMN

TYSCMN

Knoxville McGhee Tyson

Mon 6/1

6:30 am-7:15 am

2 stops19h 45m

Casablanca Mohamed V

Wed 7/1

9:00 am-11:54 pm

3 stops19h 54m

$1,433

KnoxvilleCasablanca

TYS - CMN

TYSCMN

Knoxville McGhee Tyson

Fri 6/26

5:45 am-7:15 am

3 stops20h 30m

Casablanca Mohamed V

Sun 7/5

9:00 am-11:54 pm

2 stops19h 54m

$1,494

KnoxvilleCasablanca

TYS - CMN

TYSCMN

Knoxville McGhee Tyson

Fri 5/15

9:50 am-7:15 am

2 stops16h 25m

Casablanca Mohamed V

Sat 5/23

9:00 am-8:56 pm

3 stops40h 56m

$1,498

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 38 resultsSorted by cheapest first
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Best time to book a flight from Knoxville to Africa

Have a flexible travel schedule? Discover the best time to fly to Africa from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Africa
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Africa

Get insights into the airlines that provide service to Africa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Africa. Reviews last updated April 18, 2026.
Read through reviews of airlines operating flights from Knoxville to Africa, such as Delta,United Airlines, andLufthansa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,424 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,424 reviews
Delta
7.9
Good
8,424 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,603 reviews
Delta
7.9
Good
8,424 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Lufthansa
6.8
Okay
7,930 reviews
Delta
7.9
Good
8,424 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Africa?

    If you book a flight to Africa from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • How long is the flight from Knoxville to Africa?

    Departing from Knoxville to Africa will take you 16h 47m. Airlines will cover a distance of 4229 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Knoxville to Africa?

    While some choose either Knoxville McGhee Tyson - Casablanca Mohamed V or Knoxville McGhee Tyson - Accra Kotoka, Knoxville McGhee Tyson - Nairobi Jomo Kenyatta Intl is the most popular route from Knoxville to Africa.

  • Can I find deals for flights from Knoxville to Africa that include hotel bookings?

    Yes. In addition to deals on Knoxville to Africa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Africa.

  • Can I find deals for business class flights from Knoxville to Africa?

    Yes. Cheapflights offers flight deals from Knoxville to Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from Knoxville to Africa

Discover the top 2 airlines that operate flights from Knoxville to Africa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$765Average$1,123FlexibilityNo cancel feeOn-time76%
DeltaCheapest$1,120Average$1,316FlexibilityNo cancel feeOn-timeN/A

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