$385+ Cheap flights from Missouri to Sedona, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PHX
Sep 24 — Oct 11
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Missouri to Sedona with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Sedona
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missouri to SedonaExplore the most affordable flight options available from Missouri to Sedona. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 25, 2026.
Explore the most affordable flight options available from Missouri to Sedona. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 25, 2026.
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:00 am -
1 stop5h 13m
Tue 9/2911:43 am -
1 stop7h 09m
Deal found 8/23![American Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/102:20 pm -
1 stop7h 29m
Mon 10/1912:45 pm -
1 stop5h 08m
Deal found 8/21![American Airlines logo]()
$488
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:56 am -
1 stop5h 14m
Tue 11/177:37 am -
1 stop5h 06m
Deal found 8/25![American Airlines logo]()
$522
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:59 am -
1 stop5h 14m
Sat 9/1912:37 pm -
1 stop7h 42m
Deal found 8/20![American Airlines logo]()
$532
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:43 am -
1 stop8h 10m
Sat 9/129:50 am -
1 stop7h 17m
Deal found 8/20![American Airlines logo]()
$552
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:49 pm -
2 stops9h 50m
Sat 10/2412:45 pm -
1 stop5h 03m
Deal found 8/23![American Airlines logo]()
$558
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/198:29 am -
1 stop6h 53m
Sun 11/223:00 pm -
1 stop7h 35m
Deal found 8/22![American Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:00 am -
1 stop7h 20m
Tue 9/810:30 am -
1 stop5h 07m
Deal found 8/20![American Airlines logo]()
$582
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:26 am -
1 stop5h 39m
Mon 10/1912:45 pm -
1 stop5h 22m
Deal found 8/22![American Airlines logo]()
$587
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:36 am -
1 stop5h 18m
Sat 8/2910:30 am -
1 stop5h 07m
Deal found 8/23![American Airlines logo]()
$587
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:25 pm -
1 stop7h 42m
Tue 9/1512:37 pm -
1 stop7h 42m
Deal found 8/24![American Airlines logo]()
$589
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:38 am -
2 stops12h 29m
Thu 10/812:45 pm -
1 stop7h 40m
Deal found 8/25![American Airlines logo]()
$592
Best flights from Missouri to SedonaDiscover carefully curated flight deals from Missouri to Sedona that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 25, 2026.
Discover carefully curated flight deals from Missouri to Sedona that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 25, 2026.
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:31 pm -
1 stop8h 08m
Sat 10/2411:52 am -
1 stop6h 51m
Deal found 8/23![American Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
1 stop7h 50m
Tue 11/177:37 am -
1 stop5h 06m
Deal found 8/25![American Airlines logo]()
$522
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:59 am -
1 stop5h 14m
Sat 9/1912:37 pm -
1 stop7h 42m
Deal found 8/20![American Airlines logo]()
$532
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:26 am -
2 stops12h 09m
Sat 11/141:22 pm -
1 stop5h 57m
Deal found 8/24![American Airlines logo]()
$549
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:43 am -
1 stop8h 10m
Sat 9/129:50 am -
1 stop7h 17m
Deal found 8/20![American Airlines logo]()
$552
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/206:00 am -
1 stop7h 52m
Mon 2/221:22 pm -
1 stop7h 43m
Deal found 8/23![American Airlines logo]()
$556
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/216:00 am -
1 stop7h 52m
Mon 1/251:22 pm -
1 stop7h 43m
Deal found 8/24![American Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/198:29 am -
1 stop6h 53m
Sun 11/223:00 pm -
1 stop7h 35m
Deal found 8/22![American Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:00 am -
1 stop7h 20m
Tue 9/810:30 am -
1 stop5h 07m
Deal found 8/20![American Airlines logo]()
$582
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:25 pm -
1 stop7h 42m
Tue 9/1512:37 pm -
1 stop7h 42m
Deal found 8/24![American Airlines logo]()
$589
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:38 am -
2 stops12h 29m
Thu 10/812:45 pm -
1 stop7h 40m
Deal found 8/25![American Airlines logo]()
$592
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/179:12 am -
2 stops10h 23m
Sat 11/2112:40 pm -
2 stops8h 00m
Deal found 8/24![American Airlines logo]()
$601
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/217:00 am -
1 stop6h 47m
Sat 12/261:17 pm -
1 stop6h 41m
Deal found 8/25![American Airlines logo]()
$679
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
1 stop8h 05m
Mon 10/1911:52 am -
2 stops10h 04m
Deal found 8/22![American Airlines logo]()
$791
Last-minute flights from Missouri to SedonaDiscover last-minute flight deals from Missouri to Sedona. Data last updated August 25, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Sedona. Data last updated August 25, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:36 am -
1 stop5h 18m
Sat 8/2910:30 am -
1 stop5h 07m
Deal found 8/23![American Airlines logo]()
$587
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:22 pm -
1 stop4h 58m
Sun 8/3012:35 pm -
1 stop5h 49m
Deal found 8/24![American Airlines logo]()
$592
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:00 am -
1 stop7h 20m
Tue 9/810:30 am -
1 stop5h 07m
Deal found 8/20![American Airlines logo]()
$582
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:43 am -
1 stop8h 10m
Sat 9/129:50 am -
1 stop7h 17m
Deal found 8/20![American Airlines logo]()
$552
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:00 am -
1 stop6h 53m
Sun 9/136:49 am -
1 stop4h 51m
Deal found 8/25![American Airlines logo]()
$659
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:25 pm -
1 stop7h 42m
Tue 9/1512:37 pm -
1 stop7h 42m
Deal found 8/24![American Airlines logo]()
$589
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:25 pm -
1 stop7h 42m
Mon 9/1411:43 am -
1 stop7h 16m
Deal found 8/21![American Airlines logo]()
$621
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:59 am -
1 stop5h 14m
Sat 9/1912:37 pm -
1 stop7h 42m
Deal found 8/20![American Airlines logo]()
$532
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:00 am -
1 stop5h 13m
Fri 9/2511:43 am -
1 stop7h 09m
Deal found 8/21![American Airlines logo]()
$622
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:00 am -
1 stop5h 13m
Tue 9/2911:43 am -
1 stop7h 09m
Deal found 8/23![American Airlines logo]()
$484
One-way flights from Missouri to SedonaSearch for one-way flight options from Missouri to Sedona. Find affordable one-way fares based on user searches. Data last updated August 25, 2026.
Search for one-way flight options from Missouri to Sedona. Find affordable one-way fares based on user searches. Data last updated August 25, 2026.
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:44 am -
1 stop7h 09m
Deal found 8/22![American Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:00 am -
1 stop7h 50m
Deal found 8/25![American Airlines logo]()
$412
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:20 pm -
2 stops8h 03m
Deal found 8/20![American Airlines logo]()
$495
Find flight deals from Missouri to Sedona
Keep the following information in mind while searching for Missouri to Sedona flight deals. Data was last updated August 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $484 (American Airlines) |
One-way from | $385 (American Airlines) |
Popular in | June |
Cheapest in | December |
Average price | $494 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Sedona that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 25, 2026.
Use the filters below to find and compare flights from Missouri to Sedona that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisFlagstaff
STL Lambert-St Louis - FLG Flagstaff Pulliam
STLFLG
Lambert-St Louis
Sat 10/17
2:31 pm-8:39 pm
1 stop8h 08m
Flagstaff Pulliam
Sat 10/24
11:52 am-8:43 pm
1 stop6h 51m
$484
St. LouisFlagstaff
STL Lambert-St Louis - FLG Flagstaff Pulliam
STLFLG
Lambert-St Louis
Fri 11/13
6:00 am-12:50 pm
1 stop7h 50m
Flagstaff Pulliam
Tue 11/17
7:37 am-1:43 pm
1 stop5h 06m
$522
Kansas CityFlagstaff
MCI Kansas City - FLG Flagstaff Pulliam
MCIFLG
Kansas City
Wed 9/16
7:59 am-11:13 am
1 stop5h 14m
Flagstaff Pulliam
Sat 9/19
12:37 pm-10:19 pm
1 stop7h 42m
$532
St. LouisFlagstaff
STL Lambert-St Louis - FLG Flagstaff Pulliam
STLFLG
Lambert-St Louis
Tue 11/3
7:26 am-6:35 pm
2 stops12h 09m
Flagstaff Pulliam
Sat 11/14
1:22 pm-8:19 pm
1 stop5h 57m
$549
St. LouisFlagstaff
STL Lambert-St Louis - FLG Flagstaff Pulliam
STLFLG
Lambert-St Louis
Wed 9/9
5:43 am-11:53 am
1 stop8h 10m
Flagstaff Pulliam
Sat 9/12
9:50 am-7:07 pm
1 stop7h 17m
$552
St. LouisFlagstaff
STL Lambert-St Louis - FLG Flagstaff Pulliam
STLFLG
Lambert-St Louis
Sat 2/20
6:00 am-12:52 pm
1 stop7h 52m
Flagstaff Pulliam
Mon 2/22
1:22 pm-10:05 pm
1 stop7h 43m
$556
St. LouisFlagstaff
STL Lambert-St Louis - FLG Flagstaff Pulliam
STLFLG
Lambert-St Louis
Thu 1/21
6:00 am-12:52 pm
1 stop7h 52m
Flagstaff Pulliam
Mon 1/25
1:22 pm-10:05 pm
1 stop7h 43m
$560
St. LouisFlagstaff
STL Lambert-St Louis - FLG Flagstaff Pulliam
STLFLG
Lambert-St Louis
Thu 11/19
8:29 am-2:22 pm
1 stop6h 53m
Flagstaff Pulliam
Sun 11/22
3:00 pm-11:35 pm
1 stop7h 35m
$560
Quickest round-trip
St. LouisFlagstaff
STL Lambert-St Louis - FLG Flagstaff Pulliam
STLFLG
Lambert-St Louis
Sat 9/5
8:00 am-1:20 pm
1 stop7h 20m
Flagstaff Pulliam
Tue 9/8
10:30 am-5:37 pm
1 stop5h 07m
$582
Kansas CityFlagstaff
MCI Kansas City - FLG Flagstaff Pulliam
MCIFLG
Kansas City
Fri 9/11
2:25 pm-8:07 pm
1 stop7h 42m
Flagstaff Pulliam
Tue 9/15
12:37 pm-10:19 pm
1 stop7h 42m
$589
Showing 1-10 of 17 resultsSorted by cheapest first
Best time to book a flight from Missouri to Sedona
Have a flexible travel schedule? Discover the best time to fly to Sedona from Missouri with our price prediction graph.
STL-FLG
MCI-FLG
SGF-FLG
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Sedona
USMO-SE9
STL-FLG
MCI-FLG
SGF-FLG
What is the cheapest time of day to fly from MO to SE9?
Find hourly flight availability from Missouri to Sedona. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 25, 2026.
It’s typically best to fly out from Missouri to Sedona in the evening. Doing so could potentially save you 22% on the flight price compared to flying in the morning, which is usually more expensive.
Weekly flight availability from Missouri to Sedona
Explore weekly flight availability from Missouri to Sedona. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated August 25, 2026.
The most flights from USMO to SE9 are scheduled on a Sunday (7 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Missouri to Sedona?
Airfare is typical for this route at the moment.
Missouri to Sedona flights typically cost between $479 and $650 in September.The cheapest round-trip price found within the last 5 days was $484 on American Airlines (Sep 23-Sep 29).
What is the cheapest day to fly from Missouri to Sedona?
Use this chart to determine the cheapest time to fly round-trip from Missouri to Sedona. Price data was last updated on August 22, 2026.
Travelers seeking maximum savings on their Missouri to Sedona flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Sedona. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for Missouri to Sedona
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Sedona by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Sedona by cabin class
Find flights from Missouri to Sedona, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Sedona flights
Browse other Missouri and Sedona flight options. Last updated on August 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Sedona
Find the right flight back to Missouri after your stay in Sedona
Missouri to Sedona flights
Consider these flights traveling from Missouri to Sedona.
Top 6 airlines flying from Missouri to Sedona
Discover the top 6 airlines that operate flights from Missouri to Sedona. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$68 | Average$228 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$98 | Average$334 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$148 | Average$370 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$201 | Average$485 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$235 | Average$412 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$292 | Average$380 | FlexibilityNo cancel fee | On-time62% |