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Sedona

$290+ Cheap flights from Missouri to Sedona, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PHX
Nov 21 — Nov 281
Fri 11/21
Fri 11/28
1 adult, Economy
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Find flight deals from Missouri to Sedona

Cheapest flights from Missouri to Sedona
Explore the most affordable flight options available from Missouri to Sedona. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2025.

This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/95:13 amMCI - FLG
1 stop7h 41mAmerican Airlines
Tue 12/164:04 pmFLG - MCI
1 stop6h 35mAmerican Airlines
Deal found 10/21$306
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/75:13 amMCI - FLG
2 stops8h 46mAmerican Airlines
Thu 12/1112:17 pmFLG - MCI
2 stops9h 25mAmerican Airlines
Deal found 10/20$321
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/175:15 amMCI - FLG
1 stop8h 05mAmerican Airlines
Mon 11/2410:36 amFLG - MCI
1 stop5h 24mAmerican Airlines
Deal found 10/20$356
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/99:44 amMCI - FLG
2 stops9h 48mAmerican Airlines
Thu 12/181:10 pmFLG - MCI
2 stops8h 44mAmerican Airlines
Deal found 10/21$381
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/197:10 amMCI - FLG
1 stop6h 50mAmerican Airlines
Mon 11/2410:36 amFLG - MCI
1 stop5h 24mAmerican Airlines
Deal found 10/20$406
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:00 amSTL - FLG
1 stop7h 00mAmerican Airlines
Tue 11/114:04 pmFLG - STL
1 stop6h 47mAmerican Airlines
Deal found 10/21$436
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/810:28 amSGF - FLG
2 stops9h 07mAmerican Airlines
Thu 11/134:04 pmFLG - SGF
2 stops6h 50mAmerican Airlines
Deal found 10/22$451
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:00 amSTL - FLG
1 stop6h 00mAmerican Airlines
Fri 1/24:05 pmFLG - STL
1 stop6h 46mAmerican Airlines
Deal found 10/20$486
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 amSTL - FLG
2 stops10h 35mAmerican Airlines
Fri 1/24:05 pmFLG - STL
1 stop6h 46mAmerican Airlines
Deal found 10/20$496
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/26:07 pmMCI - FLG
1 stop6h 36mAmerican Airlines
Wed 11/54:04 pmFLG - MCI
1 stop6h 34mAmerican Airlines
Deal found 10/20$501
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:00 amSTL - FLG
1 stop5h 40mAmerican Airlines
Fri 1/24:05 pmFLG - STL
1 stop6h 46mAmerican Airlines
Deal found 10/20$516
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:00 amSTL - FLG
1 stop5h 40mAmerican Airlines
Tue 1/67:24 amFLG - STL
2 stops11h 05mAmerican Airlines
Deal found 10/20$526

Cheap flight deals from Missouri to Sedona

Keep the following information in mind while searching for Missouri to Sedona flight deals. Data was last updated October 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$306
(American Airlines)

One-way from

$290
(American Airlines)

Popular in

January

Cheapest in

September

Average price

$717
Provider with most accurate pricing for Lambert-St Louis-Flagstaff Pulliam flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Flagstaff Pulliam flights.
Search Deals
From Missouri to Sedona
Search Deals
One-way flight from Missouri to Sedona
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($90 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Sedona that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
Use the filters below to find and compare flights from Missouri to Sedona that are best for you.

Fly from

Missouri

Fly to

Sedona

Route

Depart

Return

Price

Kansas CityFlagstaff

MCI - FLG

MCIFLG

Kansas City

Sun 12/7

5:13 am-11:47 am

1 stop7h 34m

Flagstaff Pulliam

Thu 12/11

1:29 pm-9:14 pm

1 stop6h 45m

$306

Kansas CityFlagstaff

MCI - FLG

MCIFLG

Kansas City

Tue 12/9

2:45 pm-6:32 pm

1 stop4h 47m

Flagstaff Pulliam

Tue 12/16

4:04 pm-11:39 pm

1 stop6h 35m

$306

Kansas CityFlagstaff

MCI - FLG

MCIFLG

Kansas City

Tue 12/9

9:44 am-3:34 pm

2 stops6h 50m

Flagstaff Pulliam

Thu 12/18

7:39 am-1:36 pm

1 stop4h 57m

$316

SpringfieldFlagstaff

SGF - FLG

SGFFLG

Springfield-Branson

Sat 2/21

7:34 am-11:47 am

1 stop5h 13m

Flagstaff Pulliam

Sat 2/28

11:18 am-8:22 pm

2 stops8h 04m

$466

St. LouisFlagstaff

STL - FLG

STLFLG

Lambert-St Louis

Thu 12/25

7:00 am-12:00 pm

1 stop6h 00m

Flagstaff Pulliam

Wed 12/31

12:30 pm-7:22 pm

1 stop5h 52m

$486

St. LouisFlagstaff

STL - FLG

STLFLG

Lambert-St Louis

Thu 12/25

7:00 am-12:00 pm

1 stop6h 00m

Flagstaff Pulliam

Fri 1/2

4:05 pm-11:51 pm

1 stop6h 46m

$486

St. LouisFlagstaff

STL - FLG

STLFLG

Lambert-St Louis

Thu 12/25

7:00 am-12:00 pm

1 stop6h 00m

Flagstaff Pulliam

Thu 1/1

4:05 pm-11:51 pm

1 stop6h 46m

$486

St. LouisFlagstaff

STL - FLG

STLFLG

Lambert-St Louis

Wed 12/24

8:00 am-12:40 pm

1 stop5h 40m

Flagstaff Pulliam

Wed 12/31

1:10 pm-9:28 pm

1 stop7h 18m

$516

St. LouisFlagstaff

STL - FLG

STLFLG

Lambert-St Louis

Tue 12/23

8:00 am-12:40 pm

1 stop5h 40m

Flagstaff Pulliam

Thu 1/1

4:05 pm-11:51 pm

1 stop6h 46m

$516

St. LouisFlagstaff

STL - FLG

STLFLG

Lambert-St Louis

Tue 12/23

8:00 am-12:40 pm

1 stop5h 40m

Flagstaff Pulliam

Tue 1/6

1:18 pm-7:29 pm

1 stop5h 11m

$516

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/20

Showing 1-10 of 18 results
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Best time to book a flight from Missouri to Sedona

Have a flexible travel schedule? Discover the best time to fly to Sedona from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Sedona

What is the cheapest month to book a flight from Missouri to Sedona?

Currently, October is the cheapest month in which you can book a flight from Missouri to Sedona (average of $120). Flying from Missouri to Sedona in June is currently the most expensive (average of $213). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SE9?

Find hourly flight availability from Missouri to Sedona. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 22, 2025.

It’s typically best to fly out from Missouri to Sedona in the evening. Doing so could potentially save you 44% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Missouri to Sedona?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Sedona. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Sedona flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Missouri to Sedona

Explore weekly flight availability from Missouri to Sedona. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated October 22, 2025.

The most flights from USMO to SE9 are scheduled on a Monday (11 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (2 on average).

Related info for your journey

Find useful and relevant information for your journey from Missouri to Sedona. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Sedona?

    There are many flights that can get you from Missouri to Sedona in 7h 34m. Fly via American Airlines to get the fastest option. The distance from Missouri to Sedona is about 974 mi.

  • What are the most popular routes from Missouri to Sedona?

    When deciding which route to take from Missouri to Sedona consider Lambert-St Louis - Flagstaff Pulliam, Kansas City - Flagstaff Pulliam or Springfield-Branson - Flagstaff Pulliam as they are the most popular.

  • What are the most reliable airlines from Missouri to Sedona?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Missouri to Sedona on time: SkyWest Airlines (100%), Southwest (76%), Alaska Airlines (72%).

  • What are the cheapest flights from Missouri to Sedona?

    While on average a flight from Missouri to Sedona is generally $425, our data shows the cheapest flight currently is $119. When looking at the most popular route, (Lambert-St Louis - Flagstaff Pulliam), you can expect to pay $416 for that flight.

  • Can I find deals for flights from Missouri to Sedona that include hotel bookings?

    Yes. In addition to deals on Missouri to Sedona flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Sedona?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Sedona.

  • Can I find deals for business class flights from Missouri to Sedona?

    Yes. Cheapflights offers flight deals from Missouri to Sedona by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Sedona?

    Currently, October is the cheapest month in which you can book a flight from Missouri to Sedona (average of $120). Flying from Missouri to Sedona in June is currently the most expensive (average of $213). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Sedona

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Missouri to Sedona

Discover the top 7 airlines that operate flights from Missouri to Sedona. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$99Average$204FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$139Average$227FlexibilityNo cancel feeOn-time65%
Allegiant AirCheapest$150Average$269FlexibilityNo cancel feeOn-time88%
SouthwestCheapest$222Average$399FlexibilityNo cancel feeOn-time63%
DeltaCheapest$234Average$342FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$237Average$510FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$250Average$438FlexibilityNo cancel feeOn-time69%

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