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Sedona

$210+ Cheap flights from Missouri to Sedona, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/20. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PHX
Mar 27 — Apr 31
Fri 3/27
Fri 4/3
1 adult, Economy
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Cheap flight deals from Missouri to Sedona

Cheapest flights from Missouri to Sedona
Explore the most affordable flight options available from Missouri to Sedona. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 25, 2026.

This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:30 am
MCI
-
FLG
1 stop6h 07m
American Airlines
Fri 9/2512:17 pm
FLG
-
MCI
1 stop7h 58m
American Airlines
Deal found 2/24$306
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/241:58 pm
MCI
-
FLG
2 stops11h 09m
American Airlines
Tue 3/316:00 am
FLG
-
MCI
1 stop5h 33m
American Airlines
Deal found 2/22$316
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:41 am
MCI
-
FLG
1 stop7h 56m
American Airlines
Tue 10/612:17 pm
FLG
-
MCI
1 stop5h 47m
American Airlines
Deal found 2/22$356
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:20 am
STL
-
FLG
1 stop8h 31m
American Airlines
Thu 5/71:30 pm
FLG
-
STL
1 stop7h 29m
American Airlines
Deal found 2/24$356
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:55 pm
MCI
-
FLG
1 stop5h 47m
American Airlines
Fri 5/157:52 pm
FLG
-
MCI
2 stops11h 02m
American Airlines
Deal found 2/23$366
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/88:23 am
SGF
-
FLG
1 stop5h 14m
American Airlines
Wed 8/1212:17 pm
FLG
-
SGF
1 stop7h 52m
American Airlines
Deal found 2/21$406
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/122:37 pm
STL
-
FLG
1 stop6h 07m
American Airlines
Sat 5/165:01 pm
FLG
-
STL
1 stop5h 11m
American Airlines
Deal found 2/24$406
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:30 am
MCI
-
FLG
1 stop8h 21m
American Airlines
Tue 5/121:30 pm
FLG
-
MCI
1 stop7h 20m
American Airlines
Deal found 2/23$416
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:50 am
MCI
-
FLG
1 stop6h 07m
American Airlines
Sun 8/3012:17 pm
FLG
-
MCI
1 stop4h 44m
American Airlines
Deal found 2/22$426
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:30 am
MCI
-
FLG
1 stop8h 21m
American Airlines
Fri 5/157:52 pm
FLG
-
MCI
2 stops12h 23m
American Airlines
Deal found 2/23$436
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/197:12 am
STL
-
FLG
1 stop7h 48m
American Airlines
Thu 4/235:01 pm
FLG
-
STL
1 stop4h 58m
American Airlines
Deal found 2/23$436
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:30 am
MCI
-
FLG
1 stop7h 21m
American Airlines
Fri 5/157:52 pm
FLG
-
MCI
2 stops12h 23m
American Airlines
Deal found 2/23$446

Find flight deals from Missouri to Sedona

Keep the following information in mind while searching for Missouri to Sedona flight deals. Data was last updated February 25, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$306
(American Airlines)

One-way from

$210
(American Airlines)

Popular in

March

Cheapest in

September

Average price

$565
Provider with most accurate pricing for Lambert-St Louis-Flagstaff Pulliam flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Flagstaff Pulliam flights.
Search Deals
From Missouri to Sedona
Search Deals
One-way flight from Missouri to Sedona
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Sedona that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 25, 2026.
Use the filters below to find and compare flights from Missouri to Sedona that are best for you.

Fly from

Missouri

Fly to

Sedona

Route

Depart

Return

Price

Kansas CityFlagstaff

MCI - FLG

MCIFLG

Kansas City

Tue 3/24

1:58 pm-11:07 pm

2 stops11h 09m

Flagstaff Pulliam

Tue 3/31

6:00 am-1:33 pm

1 stop5h 33m

$316

St. LouisFlagstaff

STL - FLG

STLFLG

Lambert-St Louis

Mon 5/4

5:20 am-11:51 am

1 stop8h 31m

Flagstaff Pulliam

Thu 5/7

1:30 pm-10:59 pm

1 stop7h 29m

$356

St. LouisFlagstaff

STL - FLG

STLFLG

Lambert-St Louis

Mon 4/27

2:37 pm-6:42 pm

1 stop6h 05m

Flagstaff Pulliam

Thu 4/30

7:52 pm-8:54 am

2 stops11h 02m

$366

SpringfieldFlagstaff

SGF - FLG

SGFFLG

Springfield-Branson

Sat 8/8

8:23 am-11:37 am

1 stop5h 14m

Flagstaff Pulliam

Wed 8/12

12:17 pm-10:09 pm

1 stop7h 52m

$406

St. LouisFlagstaff

STL - FLG

STLFLG

Lambert-St Louis

Tue 5/12

2:37 pm-6:44 pm

1 stop6h 07m

Flagstaff Pulliam

Sat 5/16

5:01 pm-12:12 am

1 stop5h 11m

$406

Kansas CityFlagstaff

MCI - FLG

MCIFLG

Kansas City

Wed 5/6

5:30 am-11:51 am

1 stop8h 21m

Flagstaff Pulliam

Fri 5/15

7:52 pm-10:15 am

2 stops12h 23m

$436

St. LouisFlagstaff

STL - FLG

STLFLG

Lambert-St Louis

Sun 4/19

7:05 am-4:31 pm

2 stops11h 26m

Flagstaff Pulliam

Thu 4/23

7:52 pm-8:24 am

2 stops10h 32m

$451

Kansas CityFlagstaff

MCI - FLG

MCIFLG

Kansas City

Tue 7/21

5:39 am-11:37 am

1 stop7h 58m

Flagstaff Pulliam

Tue 7/28

10:20 am-11:56 pm

2 stops11h 36m

$481

Kansas CityFlagstaff

MCI - FLG

MCIFLG

Kansas City

Tue 7/21

5:39 am-11:37 am

1 stop7h 58m

Flagstaff Pulliam

Sat 8/1

7:00 am-6:49 pm

2 stops9h 49m

$481

SpringfieldFlagstaff

SGF - FLG

SGFFLG

Springfield-Branson

Sun 7/19

8:15 am-11:37 am

1 stop5h 22m

Flagstaff Pulliam

Sat 7/25

12:17 pm-8:31 pm

1 stop6h 14m

$516

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/23

Showing 1-10 of 25 results
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Best time to book a flight from Missouri to Sedona

Have a flexible travel schedule? Discover the best time to fly to Sedona from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Sedona

What is the cheapest month to book a flight from Missouri to Sedona?

Currently, February is the cheapest month in which you can book a flight from Missouri to Sedona (average of $97). Flying from Missouri to Sedona in June is currently the most expensive (average of $215). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SE9?

Find hourly flight availability from Missouri to Sedona. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 25, 2026.

It’s typically best to fly out from Missouri to Sedona in the evening. Doing so could potentially save you 18% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Missouri to Sedona?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Sedona. Price data was last updated on February 21, 2026.

Travelers seeking maximum savings on their Missouri to Sedona flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Missouri to Sedona

Explore weekly flight availability from Missouri to Sedona. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 25, 2026.

The most flights from USMO to SE9 are scheduled on a Monday (14 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (3 on average).

How much does it cost to fly round-trip from Missouri to Sedona?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Sedona. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Sedona?

    There are many flights that can get you from Missouri to Sedona in 7h 26m. Fly via American Airlines to get the fastest option. The distance from Missouri to Sedona is about 974 mi.

  • What are the most popular routes from Missouri to Sedona?

    When deciding which route to take from Missouri to Sedona consider Lambert-St Louis - Flagstaff Pulliam, Kansas City - Flagstaff Pulliam or Springfield-Branson - Flagstaff Pulliam as they are the most popular.

  • What are the most reliable airlines from Missouri to Sedona?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Missouri to Sedona on time: Volaris (100%), Frontier (80%), American Airlines (77%).

  • What are the cheapest flights from Missouri to Sedona?

    While on average a flight from Missouri to Sedona is generally $328, our data shows the cheapest flight currently is $116. When looking at the most popular route, (Lambert-St Louis - Flagstaff Pulliam), you can expect to pay $356 for that flight.

  • Can I find deals for flights from Missouri to Sedona that include hotel bookings?

    Yes. In addition to deals on Missouri to Sedona flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Sedona?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Sedona.

  • Can I find deals for business class flights from Missouri to Sedona?

    Yes. Cheapflights offers flight deals from Missouri to Sedona by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Sedona?

    Currently, February is the cheapest month in which you can book a flight from Missouri to Sedona (average of $97). Flying from Missouri to Sedona in June is currently the most expensive (average of $215). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Sedona

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Top 6 airlines flying from Missouri to Sedona

Discover the top 6 airlines that operate flights from Missouri to Sedona. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 25, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$68Average$211FlexibilityNo cancel feeOn-time62%
DeltaCheapest$98Average$300FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$121Average$200FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$148Average$398FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$197Average$464FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$199Average$385FlexibilityNo cancel feeOn-time63%

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