There are current restrictions for travel to Sao Tome and Principe at this time. These restrictions are for the safety of Sao Tome and Principe citizens and travelers alike and are as follows: Sao Tome and Principe has reopened its borders. All travelers are required to have proof of a negative coronavirus PCR test taken in the 72 hours prior to their arrival. Upon arrival, travelers will need to undertake 14 days of compulsory quarantine in a private residence or hotel (at their own expense).. If you must travel during this time and are allowed to based on current restrictions, please stay informed about updated travel safety tips.