Santo Domingo

$252+ Cheap flights from San Francisco (SFO) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/14. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — SDQ
Aug 3 — Aug 101
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Cheapflights Tip: The best prices from San Francisco to Santo Domingo Las Americas are usually found in September or October, booked 27 days in advance, depart on a Tuesday or Thursday and return on a Thursday

Cheap flight deals from San Francisco to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$414
(lastminute.com)

One-way from

$252
(Avianca)

Popular in

December

Cheapest in

September

Average price

$812
From San Francisco to Santo Domingo Las Americas
One-way flight from San Francisco to Santo Domingo Las Americas
Highest demand for flights based on searches. 12% potential increase in price ($97 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($33 potential savings vs. average RT price).
Average for round-trip flights in July 2025

Find flight deals from San Francisco to Santo Domingo

Cheapest flights from San Francisco to Santo Domingo
Explore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This lastminute.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/3011:40 amSFO - SDQ
1 stop10h 35mJetBlue
Sat 9/132:34 pmSDQ - SFO
1 stop11h 36mJetBlue
Deal found 7/27$414
This Avianca deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/152:20 pmSFO - SDQ
2 stops17h 30mAvianca
Tue 8/266:10 pmSDQ - SFO
2 stops21h 25mAvianca
Deal found 7/27$487
This Copa Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/151:30 amSFO - SDQ
1 stop11h 47mCopa Airlines
Fri 9/268:59 amSDQ - SFO
1 stop17h 26mCopa Airlines
Deal found 7/27$509
This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/28:53 pmSFO - SDQ
1 stop10h 52mFrontier
Sun 8/1011:50 amSDQ - SFO
1 stop25h 35mFrontier
Deal found 7/27$532
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/101:30 amSFO - SDQ
1 stop11h 47mMultiple Airlines
Thu 9/181:20 pmSDQ - SFO
2 stops13h 39mMultiple Airlines
Deal found 7/28$548

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.

Fly from

San Francisco

Fly to

Santo Domingo

Route

Depart

Return

Price

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 8/30

11:40 am-1:15 am

1 stop10h 35m

Santo Domingo Las Americas

Sat 9/13

2:34 pm-11:10 pm

1 stop11h 36m

$414

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Fri 8/15

2:20 pm-10:50 am

2 stops17h 30m

Santo Domingo Las Americas

Tue 8/26

6:10 pm-12:35 pm

2 stops21h 25m

$487

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Mon 9/15

1:30 am-4:17 pm

1 stop11h 47m

Santo Domingo Las Americas

Fri 9/26

8:59 am-11:25 pm

1 stop17h 26m

$509

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 8/2

8:53 pm-10:45 am

1 stop10h 52m

Santo Domingo Las Americas

Sun 8/10

11:50 am-10:25 am

1 stop25h 35m

$532

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Wed 9/10

1:30 am-4:17 pm

1 stop11h 47m

Santo Domingo Las Americas

Thu 9/18

1:20 pm-11:59 pm

2 stops13h 39m

$548

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Thu 8/14

2:30 am-10:50 am

2 stops29h 20m

$252

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Fri 8/15

11:40 am-1:15 am

1 stop10h 35m

$293

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Fri 8/15

6:02 pm-4:00 pm

3 stops18h 58m

$353

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Thu 8/14

1:30 am-1:09 pm

1 stop32h 39m

$440

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from San Francisco to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santo Domingo

How far ahead should I book a flight from San Francisco to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Santo Domingo. Price data was last updated on July 25, 2025.

The price you pay for your flight from San Francisco to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 27 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from San Francisco to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from San Francisco to Santo Domingo (average of $362). Flying from San Francisco to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to SDQ?

Find hourly flight availability from San Francisco to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

It’s typically best to fly out from San Francisco to Santo Domingo in the afternoon. Doing so could potentially save you 18% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from San Francisco to Santo Domingo?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Santo Domingo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to Santo Domingo flight should consider departing on Friday afternoons when fares are most often at their lowest. Wednesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated July 29, 2025.
Read through reviews of airlines operating flights from San Francisco to Santo Domingo, such as Copa Airlines, JetBlue, and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.5

Food

6.8

Crew

8.1

Entertainment

6.8

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.

Overall

7.5

Food

6.8

Crew

8.1

Entertainment

6.8

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.

Overall

7.5

Food

6.8

Crew

8.1

Entertainment

6.8

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.

Overall

7.5

Food

6.8

Crew

8.1

Entertainment

6.8

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.

Overall

7.5

Food

6.8

Crew

8.1

Entertainment

6.8

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines flying from San Francisco to Santo Domingo round-trip?

    Currently priced at $414, JetBlue will fly you from San Francisco to Santo Domingo and back. In addition to JetBlue, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Avianca and Copa Airlines - these airlines can fly you to your destination from $487 and $509, respectively. JetBlue is 39% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from San Francisco to Santo Domingo one-way?

    The cheapest airline one-way is Avianca, with whom users have recently found tickets for as low as $252. However, be on the lookout for offers from JetBlue and Copa Airlines, as they are both options that can get you from San Francisco to Santo Domingo for a low price.

  • Can I find deals for flights from San Francisco to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on San Francisco to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santo Domingo.

  • Can I find deals for business class flights from San Francisco to Santo Domingo?

    Yes. Cheapflights offers flight deals from San Francisco to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from San Francisco to Santo Domingo (average of $362). Flying from San Francisco to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for San Francisco to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from San Francisco to Santo Domingo

Discover the top 6 airlines that operate flights from San Francisco to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$378Average$735FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$438Average$655FlexibilityNo cancel feeOn-time62%
AviancaCheapest$487Average$584FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$496Average$595FlexibilityNo cancel feeOn-time70%
DeltaCheapest$497Average$731FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$619Average$757FlexibilityNo cancel feeOn-time71%

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