$186+ Cheap flights from San Francisco (SFO) to Santo Domingo (SDQ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/9. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — SDQ
Jan 11 — Jan 181
1 adult, Economy
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Find cheap flights from San Francisco to Santo Domingo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from San Francisco to Santo Domingo Las Americas are usually found in October or January, booked 27 days in advance, depart on a Tuesday or Thursday and return on a Thursday
Cheap flight deals from San Francisco to Santo Domingo
Cheapest flights from San Francisco to Santo DomingoExplore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.
Explore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2811:20 pmSFO - SDQ
2 stops13h 29mFrontier
Thu 1/84:33 pmSDQ - SFO
1 stop24h 45mFrontier
Deal found 12/9![Frontier logo]()
$617
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:30 amSFO - SDQ
2 stops29h 59mMultiple Airlines
Fri 2/67:10 pmSDQ - SFO
1 stop31h 30mMultiple Airlines
Deal found 12/8![Multiple Airlines logo]()
$675
This JetBlue deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1510:28 amSFO - SDQ
1 stop11h 54mJetBlue
Tue 2/106:00 amSDQ - SFO
1 stop17h 15mJetBlue
Deal found 12/8![JetBlue logo]()
$676
This Expedia deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:15 amSFO - SDQ
2 stops24h 47mJetBlue
Mon 2/96:00 amSDQ - SFO
1 stop17h 15mJetBlue
Deal found 12/8![JetBlue logo]()
$678
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:30 amSFO - SDQ
2 stops29h 59mMultiple Airlines
Thu 2/126:10 amSDQ - SFO
1 stop14h 41mMultiple Airlines
Deal found 12/8![Multiple Airlines logo]()
$692
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:30 amSFO - SDQ
2 stops29h 59mMultiple Airlines
Wed 2/116:10 amSDQ - SFO
1 stop18h 58mMultiple Airlines
Deal found 12/8![Multiple Airlines logo]()
$705
This JetBlue deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/157:00 amSFO - SDQ
1 stop15h 22mJetBlue
Sat 2/73:25 pmSDQ - SFO
1 stop12h 05mJetBlue
Deal found 12/8![JetBlue logo]()
$706
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:30 amSFO - SDQ
2 stops29h 59mMultiple Airlines
Sun 2/86:10 amSDQ - SFO
1 stop18h 58mMultiple Airlines
Deal found 12/8![Multiple Airlines logo]()
$712
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:30 amSFO - SDQ
2 stops29h 59mMultiple Airlines
Mon 2/96:10 amSDQ - SFO
1 stop20h 30mMultiple Airlines
Deal found 12/8![Multiple Airlines logo]()
$716
This Frontier deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1311:33 pmSFO - SDQ
2 stops15h 42mFrontier
Thu 2/1210:56 amSDQ - SFO
2 stops24h 57mFrontier
Deal found 12/8![Frontier logo]()
$718
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1210:49 amSFO - SDQ
2 stops30h 56mMultiple Airlines
Fri 2/67:10 pmSDQ - SFO
1 stop31h 30mMultiple Airlines
Deal found 12/8![Multiple Airlines logo]()
$719
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1411:33 pmSFO - SDQ
2 stops12h 56mMultiple Airlines
Fri 2/67:10 pmSDQ - SFO
1 stop31h 30mMultiple Airlines
Deal found 12/8![Multiple Airlines logo]()
$724
Find flight deals from San Francisco to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $420 (Priceline) |
One-way from | $186 (Trip.com) |
Popular in | December |
Cheapest in | October |
Average price | $759 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.
Fly from
San Francisco
Fly to
Santo Domingo
Route
Depart
Return
Price
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Mon 1/12
1:50 pm-4:35 am
1 stop10h 45m
Santo Domingo Las Americas
Mon 1/26
6:01 am-6:55 pm
1 stop16h 54m
$423
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Tue 2/3
12:40 pm-2:53 am
1 stop10h 13m
Santo Domingo Las Americas
Sun 2/8
6:00 am-7:15 pm
1 stop17h 15m
$432
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Sat 1/24
11:59 pm-2:14 pm
1 stop10h 15m
Santo Domingo Las Americas
Fri 1/30
4:15 am-2:07 pm
1 stop13h 52m
$432
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Sun 2/1
7:00 am-1:22 am
1 stop14h 22m
Santo Domingo Las Americas
Sun 2/8
6:00 am-7:15 pm
1 stop17h 15m
$432
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Tue 2/3
12:20 pm-4:35 am
1 stop12h 15m
Santo Domingo Las Americas
Fri 2/6
3:25 pm-11:30 pm
1 stop12h 05m
$432
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Mon 2/2
7:00 am-1:17 am
1 stop14h 17m
Santo Domingo Las Americas
Sun 2/8
6:00 am-7:15 pm
1 stop17h 15m
$432
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Tue 2/3
7:00 am-1:17 am
1 stop14h 17m
Santo Domingo Las Americas
Sat 2/7
3:25 pm-11:30 pm
1 stop12h 05m
$432
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Sun 2/1
12:40 pm-2:53 am
1 stop10h 13m
Santo Domingo Las Americas
Fri 2/6
3:25 pm-11:30 pm
1 stop12h 05m
$432
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Sun 2/1
8:30 pm-4:50 pm
1 stop16h 20m
Santo Domingo Las Americas
Sat 2/7
3:25 pm-11:30 pm
1 stop12h 05m
$432
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Thu 1/22
12:42 am-6:05 pm
1 stop13h 23m
Santo Domingo Las Americas
Tue 2/10
6:00 am-11:20 pm
1 stop21h 20m
$452
Showing 1-10 of 22 results
Compare providers for flights from San Francisco to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santo Domingo in December.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy1 star | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Francisco-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Francisco-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Santo Domingo
How far ahead should I book a flight from San Francisco to Santo Domingo?
Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Santo Domingo. Price data was last updated on December 5, 2025.
The price you pay for your flight from San Francisco to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 27 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from San Francisco to Santo Domingo?
Currently, July is the cheapest month in which you can book a flight from San Francisco to Santo Domingo (average of $281). Flying from San Francisco to Santo Domingo in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SFO to SDQ?
Find hourly flight availability from San Francisco to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.
It’s typically best to fly out from San Francisco to Santo Domingo in the afternoon. Doing so could potentially save you 17% on the flight price compared to flying in the morning, which is usually more expensive.
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated December 12, 2025.
Read through reviews of airlines operating flights from San Francisco to Santo Domingo, such as Delta, Copa Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.9
Food
7.3
Boarding
8.1
Comfort
7.9
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.9
Food
7.3
Boarding
8.1
Comfort
7.9
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.9
Food
7.3
Boarding
8.1
Comfort
7.9
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.9
Food
7.3
Boarding
8.1
Comfort
7.9
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.9
Food
7.3
Boarding
8.1
Comfort
7.9
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.9
Food
7.3
Boarding
8.1
Comfort
7.9
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for San Francisco to Santo Domingo
See prices for flight routes from nearby airports that may be better suited for you.
Top 5 airlines flying from San Francisco to Santo Domingo
Discover the top 5 airlines that operate flights from San Francisco to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$453 | Average$635 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$487 | Average$584 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$497 | Average$598 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$600 | Average$939 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$619 | Average$748 | FlexibilityNo cancel fee | On-time71% |