$224+ Cheap flights from San Francisco (SFO) to Santo Domingo (SDQ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/20. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — SDQ
Apr 10 — Apr 171
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Francisco to Santo DomingoExplore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.
Explore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.
This Avianca deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Wed 4/226:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 3/6![Avianca logo]()
$441
This Avianca deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:55 pm
SFO
- SDQ
2 stops15h 00m
Avianca
Tue 4/286:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 3/6![Avianca logo]()
$459
This JetBlue deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:10 pm
SFO
- SDQ
1 stop10h 18m
JetBlue
Thu 4/231:40 pm
SDQ
- SFO
1 stop13h 16m
JetBlue
Deal found 3/7![JetBlue logo]()
$465
This Cheapflightsfares deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:10 pm
SFO
- SDQ
1 stop10h 18m
JetBlue
Fri 4/242:42 am
SDQ
- SFO
1 stop14h 39m
JetBlue
Deal found 3/9![JetBlue logo]()
$469
This KAYAK deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:05 pm
SFO
- SDQ
1 stop10h 23m
JetBlue
Fri 4/242:42 am
SDQ
- SFO
1 stop14h 39m
JetBlue
Deal found 3/9![JetBlue logo]()
$472
This FlightHub deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:10 pm
SFO
- SDQ
1 stop10h 18m
JetBlue
Fri 4/245:40 am
SDQ
- SFO
1 stop16h 42m
JetBlue
Deal found 3/7![JetBlue logo]()
$474
This Avianca deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/192:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Mon 5/256:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 3/6![Avianca logo]()
$476
This Copa Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:21 pm
SFO
- SDQ
1 stop16h 54m
Copa Airlines
Tue 9/156:06 am
SDQ
- SFO
1 stop20h 34m
Copa Airlines
Deal found 3/7![Copa Airlines logo]()
$479
This JetBlue deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:00 am
SFO
- SDQ
1 stop15h 19m
JetBlue
Thu 4/231:40 pm
SDQ
- SFO
1 stop13h 16m
JetBlue
Deal found 3/7![JetBlue logo]()
$480
This Avianca deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Wed 4/156:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 3/9![Avianca logo]()
$481
This JetBlue deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:30 pm
SFO
- SDQ
1 stop14h 12m
JetBlue
Fri 5/84:05 am
SDQ
- SFO
1 stop18h 17m
JetBlue
Deal found 3/6![JetBlue logo]()
$483
This Copa Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:21 pm
SFO
- SDQ
1 stop12h 20m
Copa Airlines
Mon 10/2612:10 pm
SDQ
- SFO
1 stop14h 30m
Copa Airlines
Deal found 3/6![Copa Airlines logo]()
$486
Best flights from San Francisco to Santo DomingoDiscover carefully curated flight deals from San Francisco to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 11, 2026.
Discover carefully curated flight deals from San Francisco to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 11, 2026.
This Avianca deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Wed 4/226:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 3/6![Avianca logo]()
$441
This Copa Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:21 pm
SFO
- SDQ
1 stop16h 54m
Copa Airlines
Tue 9/156:06 am
SDQ
- SFO
1 stop20h 34m
Copa Airlines
Deal found 3/7![Copa Airlines logo]()
$479
This JetBlue deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:30 pm
SFO
- SDQ
1 stop14h 12m
JetBlue
Fri 5/84:05 am
SDQ
- SFO
1 stop18h 17m
JetBlue
Deal found 3/6![JetBlue logo]()
$483
This JetBlue deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:55 pm
SFO
- SDQ
1 stop17h 39m
JetBlue
Thu 4/910:20 am
SDQ
- SFO
1 stop17h 38m
JetBlue
Deal found 3/8![JetBlue logo]()
$508
This Copa Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:06 pm
SFO
- SDQ
1 stop14h 07m
Copa Airlines
Sun 5/106:04 am
SDQ
- SFO
1 stop20h 36m
Copa Airlines
Deal found 3/7![Copa Airlines logo]()
$564
This JetBlue deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:05 pm
SFO
- SDQ
1 stop10h 23m
JetBlue
Thu 4/161:40 pm
SDQ
- SFO
1 stop13h 16m
JetBlue
Deal found 3/10![JetBlue logo]()
$535
This Copa Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/91:12 am
SFO
- SDQ
1 stop12h 03m
Copa Airlines
Tue 8/188:48 am
SDQ
- SFO
1 stop17h 52m
Copa Airlines
Deal found 3/6![Copa Airlines logo]()
$586
This JetBlue deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:05 pm
SFO
- SDQ
1 stop10h 23m
JetBlue
Wed 4/221:40 pm
SDQ
- SFO
1 stop13h 16m
JetBlue
Deal found 3/7![JetBlue logo]()
$607
Last-minute flights from San Francisco to Santo DomingoDiscover last-minute flight deals from San Francisco to Santo Domingo. Data last updated March 11, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Santo Domingo. Data last updated March 11, 2026 and is based on user searches.
This FlightHub deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/710:03 pm
SFO
- SDQ
1 stop13h 50m
Multiple Airlines
Thu 4/910:20 am
SDQ
- SFO
1 stop17h 38m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$488
This Avianca deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Wed 4/156:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 3/9![Avianca logo]()
$481
This Avianca deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Wed 4/226:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 3/6![Avianca logo]()
$441
This JetBlue deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:10 pm
SFO
- SDQ
1 stop10h 18m
JetBlue
Thu 4/231:40 pm
SDQ
- SFO
1 stop13h 16m
JetBlue
Deal found 3/7![JetBlue logo]()
$465
This Cheapflightsfares deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:10 pm
SFO
- SDQ
1 stop10h 18m
JetBlue
Fri 4/242:42 am
SDQ
- SFO
1 stop14h 39m
JetBlue
Deal found 3/9![JetBlue logo]()
$469
This FlightHub deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:10 pm
SFO
- SDQ
1 stop10h 18m
JetBlue
Fri 4/245:40 am
SDQ
- SFO
1 stop16h 42m
JetBlue
Deal found 3/7![JetBlue logo]()
$474
This JetBlue deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:10 pm
SFO
- SDQ
1 stop10h 18m
JetBlue
Wed 4/221:40 pm
SDQ
- SFO
1 stop13h 16m
JetBlue
Deal found 3/7![JetBlue logo]()
$491
This FlightHub deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/182:15 pm
SFO
- SDQ
2 stops18h 35m
Multiple Airlines
Fri 4/245:40 am
SDQ
- SFO
1 stop16h 42m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$494
This KAYAK deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:05 pm
SFO
- SDQ
1 stop10h 23m
JetBlue
Tue 4/287:30 pm
SDQ
- SFO
1 stop16h 53m
JetBlue
Deal found 3/9![JetBlue logo]()
$472
This JetBlue deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:00 am
SFO
- SDQ
1 stop15h 19m
JetBlue
Thu 4/231:40 pm
SDQ
- SFO
1 stop13h 16m
JetBlue
Deal found 3/7![JetBlue logo]()
$480
This SmartFares deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:20 pm
SFO
- SDQ
1 stop11h 21m
JetBlue
Tue 4/285:40 am
SDQ
- SFO
1 stop16h 42m
JetBlue
Deal found 3/10![JetBlue logo]()
$490
This Avianca deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:55 pm
SFO
- SDQ
2 stops15h 00m
Avianca
Tue 4/286:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 3/6![Avianca logo]()
$459
One-way flights from San Francisco to Santo DomingoSearch for one-way flight options from San Francisco to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated March 11, 2026.
Search for one-way flight options from San Francisco to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated March 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2010:38 pm
SFO
- SDQ
2 stops20h 07m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:00 am
SFO
- SDQ
2 stops36h 45m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$233
This Cheapflightsfares deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2010:50 pm
SFO
- SDQ
1 stop11h 10m
JetBlue
Deal found 3/9![JetBlue logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:38 pm
SFO
- SDQ
2 stops38h 51m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$236
This KAYAK deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:10 pm
SFO
- SDQ
1 stop10h 18m
JetBlue
Deal found 3/9![JetBlue logo]()
$238
This KAYAK deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:05 pm
SFO
- SDQ
1 stop10h 23m
JetBlue
Deal found 3/9![JetBlue logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
SFO
- SDQ
2 stops31h 29m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:41 pm
SFO
- SDQ
3 stops42h 48m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/89:00 pm
SFO
- SDQ
2 stops23h 12m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:40 am
SFO
- SDQ
3 stops41h 49m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$248
Find flight deals from San Francisco to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $441 (Avianca) |
One-way from | $224 (Kiwi.com) |
Popular in | March |
Cheapest in | October |
Average price | $871 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Wed 4/15
2:15 pm-11:50 am
2 stops18h 35m
Santo Domingo Las Americas
Wed 4/22
6:50 pm-12:50 pm
2 stops21h 00m
$441
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Sun 9/6
8:21 pm-4:15 pm
1 stop16h 54m
Santo Domingo Las Americas
Tue 9/15
6:06 am-11:40 pm
1 stop20h 34m
$479
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Mon 5/4
9:30 pm-2:42 pm
1 stop14h 12m
Santo Domingo Las Americas
Fri 5/8
4:05 am-7:22 pm
1 stop18h 17m
$483
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Tue 4/7
11:55 pm-8:34 pm
1 stop17h 39m
Santo Domingo Las Americas
Thu 4/9
10:20 am-12:58 am
1 stop17h 38m
$508
Quickest round-trip
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Tue 4/14
11:05 pm-12:28 pm
1 stop10h 23m
Santo Domingo Las Americas
Thu 4/16
1:40 pm-11:56 pm
1 stop13h 16m
$535
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Wed 5/6
8:06 pm-1:13 pm
1 stop14h 07m
Santo Domingo Las Americas
Sun 5/10
6:04 am-11:40 pm
1 stop20h 36m
$564
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Sun 8/9
1:12 am-4:15 pm
1 stop12h 03m
Santo Domingo Las Americas
Tue 8/18
8:48 am-11:40 pm
1 stop17h 52m
$586
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Fri 4/17
11:05 pm-12:28 pm
1 stop10h 23m
Santo Domingo Las Americas
Wed 4/22
1:40 pm-11:56 pm
1 stop13h 16m
$607
Cheapest one-way
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Fri 3/27
10:38 pm-9:45 pm
2 stops20h 07m
$302
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Thu 4/2
10:03 pm-2:53 pm
1 stop13h 50m
$342
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santo Domingo in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from San Francisco with our price prediction graph.
SFO-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Santo Domingo
How far ahead should I book a flight from San Francisco to Santo Domingo?
Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Santo Domingo. Price data was last updated on March 6, 2026.
The price you pay for your flight from San Francisco to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 27 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from San Francisco to Santo Domingo?
Currently, July is the cheapest month in which you can book a flight from San Francisco to Santo Domingo (average of $289). Flying from San Francisco to Santo Domingo in August is currently the most expensive (average of $476). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated March 11, 2026.
Read through reviews of airlines operating flights from San Francisco to Santo Domingo, such as Delta,Copa Airlines, andJetBlue. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Comfort
7.9
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Comfort
7.9
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Comfort
7.9
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Comfort
7.9
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Comfort
7.9
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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San Francisco and Santo Domingo flights
Browse other San Francisco and Santo Domingo flight options. Last updated on March 11, 2026.
Other flights from San Francisco
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Other flights to Santo Domingo
Explore flights to Santo Domingo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 11, 2026.
Top 5 airlines flying from San Francisco to Santo Domingo
Discover the top 5 airlines that operate flights from San Francisco to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$313 | Average$584 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$376 | Average$598 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$433 | Average$622 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$587 | Average$818 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$617 | Average$724 | FlexibilityNo cancel fee | On-time71% |