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Santo Domingo

$211+ Cheap flights from San Francisco (SFO) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — SDQ
Nov 26 — Dec 31
Wed 11/26
Wed 12/3
1 adult, Economy
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Cheapflights Tip: The best prices from San Francisco to Santo Domingo Las Americas are usually found in September or January, booked 27 days in advance, depart on a Tuesday or Thursday and return on a Thursday

Cheap flight deals from San Francisco to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 27, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$442
(JetBlue)

One-way from

$211
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$634
Provider with most accurate pricing for San Francisco-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for San Francisco-Santo Domingo Las Americas flights.
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From San Francisco to Santo Domingo Las Americas
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One-way flight from San Francisco to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($47 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from San Francisco to Santo Domingo

Cheapest flights from San Francisco to Santo Domingo
Explore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

This JetBlue deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2110:40 amSFO - SDQ
1 stop10h 54mJetBlue
Sat 11/223:17 pmSDQ - SFO
1 stop12h 06mJetBlue
Deal found 10/25$454
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:33 pmSFO - SDQ
1 stop11h 41mMultiple Airlines
Wed 12/104:21 pmSDQ - SFO
2 stops32h 50mMultiple Airlines
Deal found 10/25$485
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:33 pmSFO - SDQ
1 stop11h 41mMultiple Airlines
Thu 12/114:21 pmSDQ - SFO
2 stops24h 57mMultiple Airlines
Deal found 10/25$488
This Priceline deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/51:20 pmSFO - SDQ
2 stops18h 05mAvianca
Mon 11/105:45 pmSDQ - SFO
2 stops22h 15mAvianca
Deal found 10/25$490
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:33 pmSFO - SDQ
1 stop11h 41mMultiple Airlines
Tue 12/94:21 pmSDQ - SFO
2 stops25h 42mMultiple Airlines
Deal found 10/25$499
This JetBlue deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/89:44 pmSFO - SDQ
1 stop12h 33mJetBlue
Sat 11/1511:50 amSDQ - SFO
1 stop15h 41mJetBlue
Deal found 10/26$506
This JetBlue deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/38:15 amSFO - SDQ
1 stop12h 40mJetBlue
Tue 2/242:35 amSDQ - SFO
1 stop15h 04mJetBlue
Deal found 10/25$508
This JetBlue deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/89:44 pmSFO - SDQ
1 stop12h 51mJetBlue
Thu 12/118:46 pmSDQ - SFO
1 stop17h 32mJetBlue
Deal found 10/25$517
This JetBlue deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/79:44 pmSFO - SDQ
1 stop12h 51mJetBlue
Thu 12/113:45 pmSDQ - SFO
1 stop11h 48mJetBlue
Deal found 10/25$520
This JetBlue deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/79:44 pmSFO - SDQ
1 stop12h 51mJetBlue
Wed 12/103:45 pmSDQ - SFO
1 stop11h 48mJetBlue
Deal found 10/25$522
This JetBlue deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:44 pmSFO - SDQ
1 stop12h 38mJetBlue
Tue 12/93:45 pmSDQ - SFO
1 stop11h 48mJetBlue
Deal found 10/25$531
This JetBlue deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/89:44 pmSFO - SDQ
1 stop12h 51mJetBlue
Wed 12/102:06 pmSDQ - SFO
1 stop14h 06mJetBlue
Deal found 10/25$532

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.

Fly from

San Francisco

Fly to

Santo Domingo

Route

Depart

Return

Price

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Thu 1/22

11:59 pm-2:39 pm

1 stop10h 40m

Santo Domingo Las Americas

Mon 2/9

3:25 pm-11:30 pm

1 stop12h 05m

$442

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Fri 1/23

8:30 pm-5:29 pm

1 stop16h 59m

Santo Domingo Las Americas

Mon 2/9

3:25 pm-11:30 pm

1 stop12h 05m

$448

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Mon 2/16

10:40 pm-3:17 pm

1 stop12h 37m

Santo Domingo Las Americas

Mon 3/2

2:35 am-1:39 pm

1 stop15h 04m

$454

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Thu 2/19

7:55 am-3:31 am

1 stop15h 36m

Santo Domingo Las Americas

Sat 3/7

11:30 am-10:49 pm

1 stop15h 19m

$454

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sun 3/1

9:35 pm-4:04 pm

1 stop14h 29m

Santo Domingo Las Americas

Thu 3/5

11:59 pm-10:49 am

1 stop14h 50m

$454

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 12/20

8:14 am-1:23 am

1 stop13h 09m

Santo Domingo Las Americas

Mon 1/5

3:28 pm-11:30 pm

1 stop12h 02m

$454

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Thu 2/19

7:55 am-3:31 am

1 stop15h 36m

Santo Domingo Las Americas

Wed 3/4

2:35 am-1:39 pm

1 stop15h 04m

$454

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 12/6

6:00 am-3:23 pm

3 stops53h 23m

$211

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Tue 3/3

11:15 am-4:31 am

1 stop13h 16m

$215

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Wed 3/4

3:30 pm-10:03 am

1 stop14h 33m

$215

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 13 results
1
2

Compare providers for flights from San Francisco to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santo Domingo in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars
CheapfaremartPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Francisco-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Francisco-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Francisco-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Francisco-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santo Domingo

How far ahead should I book a flight from San Francisco to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Santo Domingo. Price data was last updated on October 24, 2025.

The price you pay for your flight from San Francisco to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 27 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from San Francisco to Santo Domingo?

Currently, July is the cheapest month in which you can book a flight from San Francisco to Santo Domingo (average of $281). Flying from San Francisco to Santo Domingo in May is currently the most expensive (average of $485). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to SDQ?

Find hourly flight availability from San Francisco to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 27, 2025.

It’s typically best to fly out from San Francisco to Santo Domingo in the afternoon. Doing so could potentially save you 17% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from San Francisco to Santo Domingo?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Santo Domingo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to Santo Domingo flight should consider departing on Tuesday at noon when fares are most often at their lowest. Wednesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated October 27, 2025.
Read through reviews of airlines operating flights from San Francisco to Santo Domingo, such as Delta, Copa Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,996 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
7.9
Good
7,996 reviews
Delta
7.9
Good
7,996 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,561 reviews
Delta
7.9
Good
7,996 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,996 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
JetBlue
7.2
Good
2,907 reviews
Delta
7.9
Good
7,996 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.6
Okay
2,464 reviews
Delta
7.9
Good
7,996 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Francisco to Santo Domingo?

    There are many flights that can get you from San Francisco to Santo Domingo in 10h 40m. Fly via JetBlue to get the fastest option. Airlines will cover a distance of 3424 mi.

  • What are the cheapest airlines flying from San Francisco to Santo Domingo round-trip?

    Currently priced at $378, Aeromexico will fly you from San Francisco to Santo Domingo and back. In addition to Aeromexico, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from JetBlue and Avianca - these airlines can fly you to your destination from $453 and $487, respectively. Aeromexico is 43% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from San Francisco to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on San Francisco to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santo Domingo.

  • Can I find deals for business class flights from San Francisco to Santo Domingo?

    Yes. Cheapflights offers flight deals from San Francisco to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Santo Domingo?

    Currently, July is the cheapest month in which you can book a flight from San Francisco to Santo Domingo (average of $281). Flying from San Francisco to Santo Domingo in May is currently the most expensive (average of $485). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top 6 airlines flying from San Francisco to Santo Domingo

Discover the top 6 airlines that operate flights from San Francisco to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$378Average$735FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$453Average$655FlexibilityNo cancel feeOn-time62%
AviancaCheapest$487Average$584FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$497Average$598FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$619Average$741FlexibilityNo cancel feeOn-time71%
DeltaCheapest$637Average$939FlexibilityNo cancel feeOn-timeN/A

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