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Santo Domingo

$205+ Cheap flights from San Francisco (SFO) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — SDQ
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from San Francisco to Santo Domingo

Cheapest flights from San Francisco to Santo Domingo
Explore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Flysmarter deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/198:00 am
SFO
-
SDQ
1 stop15h 37m
JetBlue
Wed 3/410:35 pm
SDQ
-
SFO
1 stop16h 55m
JetBlue
Deal found 1/21$417
This JetBlue deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:44 pm
SFO
-
SDQ
1 stop11h 35m
JetBlue
Tue 3/109:36 pm
SDQ
-
SFO
1 stop16h 52m
JetBlue
Deal found 1/21$433
This SmartFares deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1611:14 pm
SFO
-
SDQ
1 stop17h 32m
JetBlue
Thu 3/265:01 am
SDQ
-
SFO
1 stop15h 53m
JetBlue
Deal found 1/21$438
This Copa Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:12 am
SFO
-
SDQ
1 stop12h 03m
Copa Airlines
Wed 9/1612:42 pm
SDQ
-
SFO
1 stop13h 58m
Copa Airlines
Deal found 1/20$451
This JetBlue deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/2210:39 pm
SFO
-
SDQ
1 stop11h 34m
JetBlue
Wed 2/256:05 am
SDQ
-
SFO
1 stop18h 24m
JetBlue
Deal found 1/21$454
This Expedia deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:00 am
SFO
-
SDQ
1 stop14h 55m
JetBlue
Mon 3/23:28 pm
SDQ
-
SFO
1 stop22h 01m
JetBlue
Deal found 1/20$465
This Expedia deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:55 am
SFO
-
SDQ
1 stop15h 03m
JetBlue
Sat 3/145:01 am
SDQ
-
SFO
1 stop20h 27m
JetBlue
Deal found 1/21$469
This Copa Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:35 pm
SFO
-
SDQ
1 stop13h 37m
Copa Airlines
Wed 4/222:12 pm
SDQ
-
SFO
1 stop12h 28m
Copa Airlines
Deal found 1/20$471
This JetBlue deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:05 pm
SFO
-
SDQ
1 stop10h 23m
JetBlue
Fri 4/241:40 pm
SDQ
-
SFO
1 stop13h 16m
JetBlue
Deal found 1/20$472
This JetBlue deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2612:30 pm
SFO
-
SDQ
1 stop11h 18m
JetBlue
Tue 3/36:20 am
SDQ
-
SFO
1 stop17h 14m
JetBlue
Deal found 1/21$474
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/79:16 am
SFO
-
SDQ
1 stop16h 09m
Multiple Airlines
Tue 2/171:11 pm
SDQ
-
SFO
2 stops36h 28m
Multiple Airlines
Deal found 1/21$478

Find flight deals from San Francisco to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$417
(Flysmarter)

One-way from

$205
(Expedia)

Popular in

July

Cheapest in

October

Average price

$588
Provider with most accurate pricing for San Francisco-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Francisco-Santo Domingo Las Americas flights.
Search Deals
From San Francisco to Santo Domingo Las Americas
Search Deals
One-way flight from San Francisco to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($59 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.

Fly from

San Francisco

Fly to

Santo Domingo

Route

Depart

Return

Price

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Fri 2/27

8:44 pm-12:19 pm

1 stop11h 35m

Santo Domingo Las Americas

Tue 3/10

9:36 pm-11:28 am

1 stop16h 52m

$433

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Tue 6/2

2:10 pm-3:42 am

1 stop10h 32m

Santo Domingo Las Americas

Tue 6/9

8:59 pm-10:46 am

1 stop16h 47m

$433

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 5/23

6:55 am-3:42 am

1 stop17h 47m

Santo Domingo Las Americas

Tue 5/26

1:40 am-10:46 am

1 stop12h 06m

$433

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sun 2/22

10:39 pm-2:13 pm

1 stop11h 34m

Santo Domingo Las Americas

Wed 2/25

6:05 am-8:29 pm

1 stop18h 24m

$454

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Wed 3/18

8:20 am-3:31 am

1 stop16h 11m

Santo Domingo Las Americas

Mon 3/23

6:50 pm-9:49 am

1 stop17h 59m

$454

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Tue 3/17

8:25 am-1:58 am

1 stop14h 33m

Santo Domingo Las Americas

Mon 3/23

6:50 pm-9:49 am

1 stop17h 59m

$454

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Fri 3/20

12:15 pm-3:31 am

1 stop12h 16m

Santo Domingo Las Americas

Mon 3/23

6:50 pm-9:49 am

1 stop17h 59m

$454

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Tue 3/3

12:30 pm-3:18 am

1 stop10h 48m

Santo Domingo Las Americas

Mon 3/16

6:50 pm-9:49 am

1 stop17h 59m

$454

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Thu 4/16

8:35 pm-1:12 pm

1 stop13h 37m

Santo Domingo Las Americas

Wed 4/22

2:12 pm-11:40 pm

1 stop12h 28m

$471

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sun 4/19

11:05 pm-12:28 pm

1 stop10h 23m

Santo Domingo Las Americas

Fri 4/24

1:40 pm-11:56 pm

1 stop13h 16m

$472

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 21 results
1
2
3

Compare providers for flights from San Francisco to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santo Domingo in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
CheapfaremartPrice Accuracy-Trust Score*1 star
JustAirTicketPrice Accuracy-Trust Score*1 star
SmartFaresPrice Accuracy1 starTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Francisco-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Francisco-Santo Domingo flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santo Domingo

How far ahead should I book a flight from San Francisco to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Santo Domingo. Price data was last updated on January 16, 2026.

The price you pay for your flight from San Francisco to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 27 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from San Francisco to Santo Domingo?

Currently, July is the cheapest month in which you can book a flight from San Francisco to Santo Domingo (average of $281). Flying from San Francisco to Santo Domingo in May is currently the most expensive (average of $482). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated January 21, 2026.
Read through reviews of airlines operating flights from San Francisco to Santo Domingo, such as Delta, Copa Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,088 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
7.9
Good
8,088 reviews
Delta
7.9
Good
8,088 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,557 reviews
Delta
7.9
Good
8,088 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
11,174 reviews
Delta
7.9
Good
8,088 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
JetBlue
7.2
Good
2,891 reviews
Delta
7.9
Good
8,088 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.6
Okay
2,496 reviews
Delta
7.9
Good
8,088 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Francisco to Santo Domingo?

    There are many flights that can get you from San Francisco to Santo Domingo in 11h 35m. Fly via JetBlue to get the fastest option. Airlines will cover a distance of 3424 mi.

  • What are the cheapest airlines flying from San Francisco to Santo Domingo round-trip?

    Currently priced at $313, Avianca will fly you from San Francisco to Santo Domingo and back. In addition to Avianca, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Copa Airlines and JetBlue - these airlines can fly you to your destination from $420 and $445, respectively. Avianca is 51% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from San Francisco to Santo Domingo one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $183. However, be on the lookout for offers from JetBlue and Copa Airlines, as they are both options that can get you from San Francisco to Santo Domingo for a low price.

  • Can I find deals for flights from San Francisco to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on San Francisco to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santo Domingo.

  • Can I find deals for business class flights from San Francisco to Santo Domingo?

    Yes. Cheapflights offers flight deals from San Francisco to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Santo Domingo?

    Currently, July is the cheapest month in which you can book a flight from San Francisco to Santo Domingo (average of $281). Flying from San Francisco to Santo Domingo in May is currently the most expensive (average of $482). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top 5 airlines flying from San Francisco to Santo Domingo

Discover the top 5 airlines that operate flights from San Francisco to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$313Average$584FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$420Average$598FlexibilityNo cancel feeOn-time70%
JetBlueCheapest$445Average$636FlexibilityNo cancel feeOn-time62%
DeltaCheapest$587Average$818FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$619Average$734FlexibilityNo cancel feeOn-time71%

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