HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santo Domingo

$153+ Cheap flights from Jacksonville (JAX) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/12. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — SDQ
Mar 26 — Apr 21
Thu 3/26
Thu 4/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Jacksonville to Santo Domingo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Jacksonville to Santo Domingo

Cheapest flights from Jacksonville to Santo Domingo
Explore the most affordable flight options available from Jacksonville to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 24, 2026.

This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:17 am
JAX
-
SDQ
1 stop12h 15m
Delta
Sun 3/18:45 pm
SDQ
-
JAX
1 stop14h 49m
Delta
Deal found 2/20$345
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:15 am
JAX
-
SDQ
2 stops13h 03m
Delta
Thu 5/142:45 pm
SDQ
-
JAX
1 stop9h 33m
Delta
Deal found 2/20$349
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:44 pm
JAX
-
SDQ
1 stop13h 36m
American Airlines
Sun 5/105:55 pm
SDQ
-
JAX
1 stop6h 04m
American Airlines
Deal found 2/20$350
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:00 am
JAX
-
SDQ
1 stop16h 53m
American Airlines
Tue 3/35:07 pm
SDQ
-
JAX
1 stop7h 52m
American Airlines
Deal found 2/22$352
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:04 pm
JAX
-
SDQ
2 stops17h 56m
American Airlines
Tue 3/315:50 pm
SDQ
-
JAX
1 stop15h 13m
American Airlines
Deal found 2/22$357
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:00 am
JAX
-
SDQ
1 stop8h 59m
American Airlines
Thu 4/165:55 pm
SDQ
-
JAX
1 stop6h 04m
American Airlines
Deal found 2/23$395
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/238:05 pm
JAX
-
SDQ
1 stop12h 55m
American Airlines
Thu 3/265:50 pm
SDQ
-
JAX
1 stop6h 09m
American Airlines
Deal found 2/20$418
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:10 pm
JAX
-
SDQ
1 stop12h 29m
American Airlines
Mon 3/26:50 pm
SDQ
-
JAX
1 stop15h 13m
American Airlines
Deal found 2/23$419
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:00 am
JAX
-
SDQ
1 stop14h 58m
American Airlines
Mon 8/317:25 pm
SDQ
-
JAX
2 stops13h 44m
American Airlines
Deal found 2/20$422

Find flight deals from Jacksonville to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Jacksonville (JAX) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$345
(Delta)

One-way from

$153
(Priceline)

Popular in

December

Cheapest in

June

Average price

$558
Provider with most accurate pricing for Jacksonville-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jacksonville-Santo Domingo Las Americas flights.
Search Deals
From Jacksonville to Santo Domingo Las Americas
Search Deals
One-way flight from Jacksonville to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 25% potential increase in price ($192 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($40 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 24, 2026.
Use the filters below to find and compare flights from Jacksonville to Santo Domingo that are best for you.

Fly from

Jacksonville

Fly to

Santo Domingo

Route

Depart

Return

Price

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 5/7

7:35 am-6:18 pm

1 stop10h 43m

Santo Domingo Las Americas

Thu 5/14

2:45 pm-10:55 pm

1 stop8h 10m

$345

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 3/5

11:17 am-12:32 am

1 stop12h 15m

Santo Domingo Las Americas

Sun 3/8

8:25 pm-10:32 am

1 stop14h 07m

$345

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 5/7

6:47 pm-9:20 am

2 stops14h 33m

Santo Domingo Las Americas

Thu 5/14

2:25 pm-9:03 am

2 stops18h 38m

$349

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Wed 3/18

6:30 am-11:53 pm

2 stops17h 23m

Santo Domingo Las Americas

Sat 3/28

3:55 pm-11:59 pm

1 stop8h 04m

$349

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 5/7

8:19 pm-1:18 pm

2 stops16h 59m

Santo Domingo Las Americas

Sun 5/10

4:00 pm-11:59 pm

1 stop7h 59m

$354

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Wed 3/18

6:00 am-11:53 pm

1 stop17h 53m

Santo Domingo Las Americas

Sun 3/29

2:35 pm-10:01 pm

1 stop7h 26m

$456

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Wed 3/18

6:30 am-6:55 pm

2 stops12h 25m

Santo Domingo Las Americas

Mon 3/23

8:25 pm-2:52 pm

2 stops18h 27m

$460

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 3/19

7:00 am-1:22 pm

1 stop6h 22m

Santo Domingo Las Americas

Fri 3/27

9:45 am-3:49 pm

1 stop6h 04m

$491

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 3/5

6:00 am-5:50 pm

1 stop10h 50m

Santo Domingo Las Americas

Sun 3/8

4:03 pm-8:51 am

2 stops16h 48m

$502

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Sun 5/10

6:05 am-1:24 pm

1 stop7h 19m

$161

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/22

Showing 1-10 of 19 results
1
2

Compare providers for flights from Jacksonville to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Jacksonville to Santo Domingo in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars
MytripPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Jacksonville-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Jacksonville-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Jacksonville-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Jacksonville-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Jacksonville-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Jacksonville to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to Santo Domingo

What is the cheapest month to book a flight from Jacksonville to Santo Domingo?

Currently, June is the cheapest month in which you can book a flight from Jacksonville to Santo Domingo (average of $158). Flying from Jacksonville to Santo Domingo in November is currently the most expensive (average of $475). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated February 24, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Jacksonville to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,239 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,239 reviews
Delta
7.9
Good
8,239 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,343 reviews
Delta
7.9
Good
8,239 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Jacksonville to Santo Domingo?

    For as low as $345, Delta can have you in Santo Domingo from Jacksonville in 10h 43m. Airlines will cover a distance of 1123 mi.

  • What are the cheapest airlines flying from Jacksonville to Santo Domingo round-trip?

    Our cheapest airline available from Jacksonville to Santo Domingo is Delta. Our recent data shows that you can find tickets from as low as $154 on this airline. An additional option worth looking into is American Airlines, starting at $424. Delta is 72% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Jacksonville to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Jacksonville to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to Santo Domingo.

  • Can I find deals for business class flights from Jacksonville to Santo Domingo?

    Yes. Cheapflights offers flight deals from Jacksonville to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Jacksonville to Santo Domingo?

    Currently, June is the cheapest month in which you can book a flight from Jacksonville to Santo Domingo (average of $158). Flying from Jacksonville to Santo Domingo in November is currently the most expensive (average of $475). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Jacksonville to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
Orlando to Punta Cana flights
Fort Lauderdale to Punta Cana flights
Miami to Punta Cana flights
Orlando to Santo Domingo flights
Fort Lauderdale to Santo Domingo flights
Miami to Santo Domingo flights
Orlando to Santiago de los Caballeros flights
Tampa to Punta Cana flights
Fort Lauderdale to Santiago de los Caballeros flights
Miami to Santiago de los Caballeros flights
Tampa to Santo Domingo flights
Miami to Puerto Plata flights
Jacksonville to Punta Cana flights
Orlando to Puerto Plata flights
Miami to La Romana flights
West Palm Beach to Punta Cana flights
Tampa to Santiago de los Caballeros flights
Pensacola to Punta Cana flights
West Palm Beach to Santo Domingo flights
Pensacola to Santo Domingo flights
Fort Myers to Punta Cana flights
Sarasota to Punta Cana flights
Fort Lauderdale to Puerto Plata flights
West Palm Beach to Santiago de los Caballeros flights
Jacksonville to Santiago de los Caballeros flights
Pensacola to Santiago de los Caballeros flights
Jacksonville to Puerto Plata flights
Tampa to Puerto Plata flights
Fort Myers to Santo Domingo flights
Tallahassee to Punta Cana flights
Sarasota to Santo Domingo flights
Daytona Beach to Punta Cana flights
Melbourne to Punta Cana flights
Panama City to Punta Cana flights
Melbourne to Santo Domingo flights
Daytona Beach to Santo Domingo flights
West Palm Beach to Puerto Plata flights
Miami to Nagua flights
Gainesville to Punta Cana flights
Valparaiso to Santo Domingo flights
Fort Myers to Santiago de los Caballeros flights
Orlando to Nagua flights
Daytona Beach to Puerto Plata flights
Daytona Beach to Santiago de los Caballeros flights
Valparaiso to Santiago de los Caballeros flights
Valparaiso to Punta Cana flights

Top 2 airlines flying from Jacksonville to Santo Domingo

Discover the top 2 airlines that operate flights from Jacksonville to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$154Average$453FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$424Average$559FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.