$281+ Cheap flights from Fort Myers (RSW) to Santo Domingo (SDQ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — SDQ
May 28 — Jun 41
Round-trip
1 adult, Economy
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Find cheap flights from Fort Myers to Santo Domingo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Fort Myers to Santo Domingo
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Last-minute
One-way
Cheapest flights from Fort Myers to Santo DomingoExplore the most affordable flight options available from Fort Myers to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
Explore the most affordable flight options available from Fort Myers to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
This Travelocity deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/118:16 pm
RSW
- SDQ
1 stop14h 50m
Multiple Airlines
Wed 6/177:25 am
SDQ
- RSW
1 stop16h 30m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$521
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:16 am
RSW
- SDQ
2 stops16h 39m
American Airlines
Wed 6/177:35 pm
SDQ
- RSW
2 stops23h 04m
American Airlines
Deal found 4/27![American Airlines logo]()
$545
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/253:57 pm
RSW
- SDQ
2 stops21h 18m
American Airlines
Mon 6/110:25 am
SDQ
- RSW
2 stops22h 42m
American Airlines
Deal found 4/26![American Airlines logo]()
$565
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:26 pm
RSW
- SDQ
1 stop12h 15m
Delta
Tue 6/22:48 pm
SDQ
- RSW
1 stop9h 39m
Delta
Deal found 4/26![Delta logo]()
$575
This Travelocity deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:52 pm
RSW
- SDQ
1 stop8h 54m
JetBlue
Fri 5/221:26 pm
SDQ
- RSW
1 stop27h 11m
JetBlue
Deal found 4/26![JetBlue logo]()
$589
This Expedia deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/108:01 pm
RSW
- SDQ
1 stop15h 04m
Multiple Airlines
Tue 5/124:20 pm
SDQ
- RSW
1 stop27h 07m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$597
This Justfly.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
RSW
- SDQ
1 stop19h 54m
JetBlue
Thu 5/215:30 am
SDQ
- RSW
1 stop12h 32m
JetBlue
Deal found 4/23![JetBlue logo]()
$630
Best flights from Fort Myers to Santo DomingoDiscover carefully curated flight deals from Fort Myers to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
Discover carefully curated flight deals from Fort Myers to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
This FlightHub deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/118:16 pm
RSW
- SDQ
1 stop14h 50m
Multiple Airlines
Wed 6/175:55 am
SDQ
- RSW
1 stop18h 00m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$536
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:26 pm
RSW
- SDQ
1 stop12h 15m
Delta
Tue 6/22:48 pm
SDQ
- RSW
1 stop9h 39m
Delta
Deal found 4/26![Delta logo]()
$575
This Justfly.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
RSW
- SDQ
1 stop19h 54m
JetBlue
Thu 5/215:30 am
SDQ
- RSW
1 stop12h 32m
JetBlue
Deal found 4/23![JetBlue logo]()
$630
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:02 am
RSW
- SDQ
1 stop16h 44m
United Airlines
Mon 6/16:00 am
SDQ
- RSW
1 stop16h 17m
United Airlines
Deal found 4/26![United Airlines logo]()
$669
This FlightHub deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1112:35 pm
RSW
- SDQ
2 stops24h 31m
JetBlue
Wed 6/177:25 am
SDQ
- RSW
1 stop16h 30m
JetBlue
Deal found 4/26![JetBlue logo]()
$647
This JetBlue deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1811:07 am
RSW
- SDQ
1 stop15h 39m
JetBlue
Thu 5/215:30 am
SDQ
- RSW
1 stop11h 42m
JetBlue
Deal found 4/22![JetBlue logo]()
$648
This JetBlue deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:00 am
RSW
- SDQ
1 stop9h 51m
JetBlue
Thu 6/1810:10 am
SDQ
- RSW
1 stop13h 57m
JetBlue
Deal found 4/27![JetBlue logo]()
$677
Last-minute flights from Fort Myers to Santo DomingoDiscover last-minute flight deals from Fort Myers to Santo Domingo. Data last updated April 28, 2026 and is based on user searches.
Discover last-minute flight deals from Fort Myers to Santo Domingo. Data last updated April 28, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/108:01 pm
RSW
- SDQ
1 stop15h 04m
Multiple Airlines
Tue 5/124:20 pm
SDQ
- RSW
1 stop27h 07m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$597
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
RSW
- SDQ
2 stops16h 55m
American Airlines
Thu 5/217:35 pm
SDQ
- RSW
2 stops19h 31m
American Airlines
Deal found 4/23![American Airlines logo]()
$590
This Justfly.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
RSW
- SDQ
1 stop19h 54m
JetBlue
Thu 5/215:30 am
SDQ
- RSW
1 stop12h 32m
JetBlue
Deal found 4/23![JetBlue logo]()
$630
This FlightHub deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:16 pm
RSW
- SDQ
1 stop14h 49m
Multiple Airlines
Thu 5/219:05 pm
SDQ
- RSW
2 stops48h 24m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$654
This Travelocity deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:52 pm
RSW
- SDQ
1 stop8h 54m
JetBlue
Fri 5/221:26 pm
SDQ
- RSW
1 stop27h 11m
JetBlue
Deal found 4/26![JetBlue logo]()
$589
This JetBlue deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1811:07 am
RSW
- SDQ
1 stop15h 39m
JetBlue
Thu 5/215:30 am
SDQ
- RSW
1 stop11h 42m
JetBlue
Deal found 4/22![JetBlue logo]()
$648
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/253:57 pm
RSW
- SDQ
2 stops21h 18m
American Airlines
Mon 6/110:25 am
SDQ
- RSW
2 stops22h 42m
American Airlines
Deal found 4/26![American Airlines logo]()
$565
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:15 am
RSW
- SDQ
2 stops16h 40m
American Airlines
Tue 6/24:18 pm
SDQ
- RSW
2 stops16h 49m
American Airlines
Deal found 4/26![American Airlines logo]()
$545
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:26 pm
RSW
- SDQ
1 stop12h 15m
Delta
Tue 6/22:48 pm
SDQ
- RSW
1 stop9h 39m
Delta
Deal found 4/26![Delta logo]()
$575
One-way flights from Fort Myers to Santo DomingoSearch for one-way flight options from Fort Myers to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
Search for one-way flight options from Fort Myers to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:19 pm
RSW
- SDQ
2 stops27h 10m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:00 am
RSW
- SDQ
3 stops32h 06m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/301:19 pm
RSW
- SDQ
3 stops51h 10m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:01 pm
RSW
- SDQ
2 stops37h 52m
Frontier
Deal found 4/22![Frontier logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/318:01 pm
RSW
- SDQ
2 stops20h 28m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:19 pm
RSW
- SDQ
2 stops32h 26m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$305
This KAYAK deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3012:41 pm
RSW
- SDQ
1 stop11h 39m
JetBlue
Deal found 4/22![JetBlue logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:01 pm
RSW
- SDQ
3 stops31h 29m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$316
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:26 pm
RSW
- SDQ
1 stop12h 15m
Delta
Deal found 4/22![Delta logo]()
$318
Find flight deals from Fort Myers to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from Fort Myers (RSW) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $521 (Travelocity) |
One-way from | $281 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Fort Myers to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Fort Myers to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Fort MyersSanto Domingo
RSW - SDQ
RSWSDQ
Fort Myers SW Florida Intl
Thu 6/11
8:16 pm-11:06 am
1 stop14h 50m
Santo Domingo Las Americas
Wed 6/17
5:55 am-11:55 pm
1 stop18h 00m
$536
Quickest round-trip
Fort MyersSanto Domingo
RSW - SDQ
RSWSDQ
Fort Myers SW Florida Intl
Tue 5/26
12:26 pm-12:41 am
1 stop12h 15m
Santo Domingo Las Americas
Tue 6/2
2:48 pm-12:27 am
1 stop9h 39m
$575
Fort MyersSanto Domingo
RSW - SDQ
RSWSDQ
Fort Myers SW Florida Intl
Thu 5/14
6:00 am-1:54 am
1 stop19h 54m
Santo Domingo Las Americas
Thu 5/21
5:30 am-6:02 pm
1 stop12h 32m
$630
Fort MyersSanto Domingo
RSW - SDQ
RSWSDQ
Fort Myers SW Florida Intl
Thu 6/11
12:35 pm-1:06 pm
2 stops24h 31m
Santo Domingo Las Americas
Wed 6/17
7:25 am-11:55 pm
1 stop16h 30m
$647
Fort MyersSanto Domingo
RSW - SDQ
RSWSDQ
Fort Myers SW Florida Intl
Mon 5/18
11:07 am-2:46 am
1 stop15h 39m
Santo Domingo Las Americas
Thu 5/21
5:30 am-5:12 pm
1 stop11h 42m
$648
Fort MyersSanto Domingo
RSW - SDQ
RSWSDQ
Fort Myers SW Florida Intl
Mon 5/25
6:02 am-10:46 pm
1 stop16h 44m
Santo Domingo Las Americas
Mon 6/1
6:00 am-10:17 pm
1 stop16h 17m
$669
Fort MyersSanto Domingo
RSW - SDQ
RSWSDQ
Fort Myers SW Florida Intl
Thu 6/11
6:00 am-3:51 pm
1 stop9h 51m
Santo Domingo Las Americas
Thu 6/18
10:10 am-12:07 am
1 stop13h 57m
$677
Cheapest one-way
Fort MyersSanto Domingo
RSW - SDQ
RSWSDQ
Fort Myers SW Florida Intl
Thu 5/28
1:19 pm-4:29 pm
2 stops27h 10m
$281
Fort MyersSanto Domingo
RSW - SDQ
RSWSDQ
Fort Myers SW Florida Intl
Sun 5/31
12:26 pm-12:41 am
1 stop12h 15m
$318
Fort MyersSanto Domingo
RSW - SDQ
RSWSDQ
Fort Myers SW Florida Intl
Tue 5/26
12:26 pm-12:41 am
1 stop12h 15m
$318
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Fort Myers to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to Santo Domingo in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Fort Myers-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Fort Myers-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Fort Myers-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Fort Myers-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Fort Myers to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Fort Myers with our price prediction graph.
RSW-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Fort Myers to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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