What are the cheapest airlines flying from Jacksonville to Santiago de los Caballeros round-trip?

According to our current data, Delta ($443), American Airlines ($466), and JetBlue ($537) offers the cheapest pricing from Jacksonville to Santiago de los Caballeros. Users have found that Delta is 26% cheaper than the other options available to this destination.

What is the cheapest day to fly from Jacksonville to Santiago de los Caballeros?

Travelers seeking maximum savings on their Jacksonville to Santiago de los Caballeros flight should consider departing on Saturday mornings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

What is the cheapest day to fly round-trip from Jacksonville to Santiago de los Caballeros?

Sunday flights are found to be more expensive to fly from Jacksonville to Santiago de los Caballeros. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Santiago de los Caballeros.

What is the cheapest month to fly from Jacksonville to Santiago de los Caballeros?

Due to multiple factors, expect to potentially pay more when booking in January. For low rates, March can be a great choice for travel to Santiago de los Caballeros. Flights to Santiago de los Caballeros from Jacksonville in March are about $600 on average during March, but can be found for as low as $418.

How can I find direct flights from Jacksonville to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to Santiago de los Caballeros.

Can I find deals for business class flights from Jacksonville to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from Jacksonville to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$443+ Flights from Jacksonville to Santiago de los Caballeros

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Cheap flight deals from Jacksonville to Santiago de los Caballeros

Round-trip from	$443 (Delta)
Popular in	January
Cheapest in	March
Average price	$812

From Jacksonville to Santiago de los Caballeros

Search Deals

Highest demand for flights based on searches. 14% potential increase in price ($99 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($28 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in July 2025

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Find flight deals from Jacksonville to Santiago de los Caballeros

Cheapest flights from Jacksonville to Santiago de los Caballeros
Explore the most affordable flight options available from Jacksonville to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 11, 2025.

Mon 9/17:00 amJAX - STI

1 stop12h 24mDelta

Thu 9/118:40 pmSTI - JAX

1 stop14h 03mDelta

Deal found 7/10

$443

Sun 8/246:00 amJAX - STI

1 stop6h 31mAmerican Airlines

Sun 8/317:00 amSTI - JAX

1 stop15h 14mAmerican Airlines

Deal found 7/10

$466

Wed 9/36:25 amJAX - STI

1 stop7h 50mJetBlue

Wed 9/106:20 amSTI - JAX

1 stop9h 57mJetBlue

Deal found 7/10

$537

Fri 8/111:47 amJAX - STI

2 stops22h 03mMultiple Airlines

Tue 8/510:55 amSTI - JAX

3 stops22h 58mMultiple Airlines

Deal found 7/8

$560

Best flights from Jacksonville to Santiago de los Caballeros
Discover carefully curated flight deals from Jacksonville to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 11, 2025.

Mon 9/17:00 amJAX - STI

1 stop12h 24mDelta

Thu 9/118:40 pmSTI - JAX

1 stop14h 03mDelta

Deal found 7/10

$443

Sun 8/246:00 amJAX - STI

1 stop6h 31mAmerican Airlines

Sun 8/317:00 amSTI - JAX

1 stop15h 14mAmerican Airlines

Deal found 7/10

$466

Wed 9/36:25 amJAX - STI

1 stop7h 50mJetBlue

Wed 9/106:20 amSTI - JAX

1 stop9h 57mJetBlue

Deal found 7/10

$537

Fri 8/111:47 amJAX - STI

2 stops22h 03mMultiple Airlines

Tue 8/510:55 amSTI - JAX

3 stops22h 58mMultiple Airlines

Deal found 7/8

$560

Last-minute flights from Jacksonville to Santiago de los Caballeros
Discover last-minute flight deals from Jacksonville to Santiago de los Caballeros. Data last updated July 11, 2025 and is based on user searches.

Sat 7/197:56 amJAX - STI

1 stop13h 23mAmerican Airlines

Sun 7/277:04 amSTI - JAX

1 stop26h 24mAmerican Airlines

Deal found 7/9

$650

Sat 7/196:20 amJAX - STI

1 stop14h 53mJetBlue

Sat 7/262:17 amSTI - JAX

1 stop11h 12mJetBlue

Deal found 7/8

$888

Tue 7/226:20 amJAX - STI

1 stop14h 53mJetBlue

Sun 7/2710:38 pmSTI - JAX

2 stops34h 29mJetBlue

Deal found 7/8

$598

Fri 8/111:47 amJAX - STI

2 stops22h 03mMultiple Airlines

Tue 8/510:55 amSTI - JAX

3 stops22h 58mMultiple Airlines

Deal found 7/8

$560

Sun 8/246:00 amJAX - STI

1 stop6h 31mAmerican Airlines

Sun 8/317:00 amSTI - JAX

1 stop15h 14mAmerican Airlines

Deal found 7/10

$466

Cheapflights Fare Finder

Use the filters below to find and compare flights from Jacksonville to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Mon 9/1

7:00 am-7:24 pm

1 stop12h 24m

Santiago de los Caballeros

Thu 9/11

8:40 pm-10:43 am

1 stop14h 03m

$443

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Sun 8/24

6:00 am-12:31 pm

1 stop6h 31m

Santiago de los Caballeros

Sun 8/31

7:00 am-10:14 pm

1 stop15h 14m

$466

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Wed 9/3

6:25 am-2:15 pm

1 stop7h 50m

Santiago de los Caballeros

Wed 9/10

6:20 am-4:17 pm

1 stop9h 57m

$537

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Fri 8/1

11:47 am-9:50 am

2 stops22h 03m

Santiago de los Caballeros

Tue 8/5

10:55 am-9:53 am

3 stops22h 58m

$560

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/10

Best time to book a flight from Jacksonville to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Jacksonville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to Santiago de los Caballeros

What is the cheapest month to book a flight from Jacksonville to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Jacksonville to Santiago de los Caballeros (average of $347). Flying from Jacksonville to Santiago de los Caballeros in July is currently the most expensive (average of $628). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from JAX to STI?

It’s optimal to fly from Jacksonville to Santiago de los Caballeros in the morning. By choosing this option you can save up to 25% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Santiago de los Caballeros

See what other customers who have flown with Delta, JetBlue, and American Airlines from Jacksonville to Santiago de los Caballeros have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,951 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Delta

8.0

Very good

7,951 reviews

Delta

8.0

Very good

7,951 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

JetBlue

7.3

Good

2,913 reviews

Delta

8.0

Very good

7,951 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,951 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

Related info for your journey

What are the cheapest airlines flying from Jacksonville to Santiago de los Caballeros round-trip?
According to our current data, Delta ($443), American Airlines ($466), and JetBlue ($537) offers the cheapest pricing from Jacksonville to Santiago de los Caballeros. Users have found that Delta is 26% cheaper than the other options available to this destination.
Can I find deals for flights from Jacksonville to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on Jacksonville to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Jacksonville to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to Santiago de los Caballeros.
Can I find deals for business class flights from Jacksonville to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from Jacksonville to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Jacksonville to Santiago de los Caballeros?
Currently, May is the cheapest month in which you can book a flight from Jacksonville to Santiago de los Caballeros (average of $347). Flying from Jacksonville to Santiago de los Caballeros in July is currently the most expensive (average of $628). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from Jacksonville to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$411	Average$642	FlexibilityNo cancel fee	On-time71%

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$443+ Cheap flights from Jacksonville (JAX) to Santiago de los Caballeros (STI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Jacksonville to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Jacksonville to Santiago de los Caballeros

Round-trip from

Popular in

Cheapest in

Average price

Find flight deals from Jacksonville to Santiago de los Caballeros

Cheapest flights from Jacksonville to Santiago de los CaballerosExplore the most affordable flight options available from Jacksonville to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 11, 2025.

Explore the most affordable flight options available from Jacksonville to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 11, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Jacksonville to Santiago de los Caballeros that are best for you.

Best time to book a flight from Jacksonville to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Jacksonville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to Santiago de los Caballeros

What is the cheapest month to book a flight from Jacksonville to Santiago de los Caballeros?

What is the cheapest time of day to fly from JAX to STI?

Find hourly flight availability from Jacksonville to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 11, 2025.

Reviews of airlines servicing Santiago de los Caballeros

See what other customers who have flown with Delta, JetBlue, and American Airlines from Jacksonville to Santiago de los Caballeros have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Jacksonville to Santiago de los Caballeros round-trip?

Can I find deals for flights from Jacksonville to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from Jacksonville to Santiago de los Caballeros?

Can I find deals for business class flights from Jacksonville to Santiago de los Caballeros?

What is the cheapest month to book a flight from Jacksonville to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Jacksonville to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Jacksonville to Santiago de los Caballeros

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Book with Flexibility

Travel Smart

Cheapest flights from Jacksonville to Santiago de los Caballeros
Explore the most affordable flight options available from Jacksonville to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 11, 2025.