How long is the flight from Myrtle Beach to Santiago?

For as low as $754, LATAM Airlines can have you in Santiago from Myrtle Beach in 23h 55m. Myrtle Beach and Santiago are separated by a distance of 4661 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

What is the cheapest time of day to fly from MYR to SCL?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Myrtle Beach to Santiago as you normally would.

Can I find deals for flights from Myrtle Beach to Santiago that include hotel bookings?

Yes. In addition to deals on Myrtle Beach to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Myrtle Beach to Santiago?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Santiago.

Can I find deals for business class flights from Myrtle Beach to Santiago?

Yes. Cheapflights offers flight deals from Myrtle Beach to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$330+ Flights from Myrtle Beach to Santiago

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Myrtle Beach to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Myrtle Beach to Santiago

Cheapest flights from Myrtle Beach to Santiago
Explore the most affordable flight options available from Myrtle Beach to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 25, 2025.

Sat 12/64:00 pmMYR - SCL

1 stop13h 40mDelta

Wed 12/1011:10 pmSCL - MYR

1 stop12h 37mDelta

Deal found 11/23

$754

Best flights from Myrtle Beach to Santiago
Discover carefully curated flight deals from Myrtle Beach to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 25, 2025.

Sat 12/610:32 amMYR - SCL

2 stops25h 33mLATAM Airlines

Tue 12/94:35 amSCL - MYR

2 stops21h 08mLATAM Airlines

Deal found 11/22

$754

Sat 12/64:00 pmMYR - SCL

2 stops23h 55mDelta

Wed 12/107:25 amSCL - MYR

2 stops32h 30mDelta

Deal found 11/23

$754

Last-minute flights from Myrtle Beach to Santiago
Discover last-minute flight deals from Myrtle Beach to Santiago. Data last updated November 25, 2025 and is based on user searches.

Sat 12/64:00 pmMYR - SCL

1 stop13h 40mDelta

Wed 12/1011:10 pmSCL - MYR

1 stop12h 37mDelta

Deal found 11/23

$754

One-way flights from Myrtle Beach to Santiago
Search for one-way flight options from Myrtle Beach to Santiago. Find affordable one-way fares based on user searches. Data last updated November 25, 2025.

Sat 1/109:53 amMYR - SCL

3 stops50h 47mMultiple Airlines

Deal found 11/22

$330

Sat 1/1010:33 amMYR - SCL

1 stop19h 07mDelta

Deal found 11/22

$558

Cheap flight deals from Myrtle Beach to Santiago

Round-trip from	$754 (Delta)
One-way from	$330 (Kiwi.com)

From Myrtle Beach Intl to Santiago Arturo Merino Benitez

Search Deals

One-way flight from Myrtle Beach Intl to Santiago Arturo Merino Benitez

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Myrtle Beach to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Sat 12/6

10:32 am-2:05 pm

2 stops25h 33m

Santiago Arturo Merino Benitez

Tue 12/9

4:35 am-11:43 pm

2 stops21h 08m

$754

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Sat 12/6

4:00 pm-5:55 pm

2 stops23h 55m

Santiago Arturo Merino Benitez

Wed 12/10

7:25 am-1:55 pm

2 stops32h 30m

$754

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Sat 1/10

9:53 am-2:40 pm

3 stops50h 47m

$330

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Sat 1/10

10:33 am-7:40 am

1 stop19h 07m

$558

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/22

Best time to book a flight from Myrtle Beach to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Myrtle Beach with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

How long is the flight from Myrtle Beach to Santiago?
For as low as $754, LATAM Airlines can have you in Santiago from Myrtle Beach in 23h 55m. Myrtle Beach and Santiago are separated by a distance of 4661 mi. This flight may include one or multiple stops.
Can I find deals for flights from Myrtle Beach to Santiago that include hotel bookings?
Yes. In addition to deals on Myrtle Beach to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Myrtle Beach to Santiago?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Santiago.
Can I find deals for business class flights from Myrtle Beach to Santiago?
Yes. Cheapflights offers flight deals from Myrtle Beach to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Myrtle Beach to Santiago

Charlotte to Santiago flights

Charleston to Santiago flights

Greenville to Santiago flights

Savannah to Santiago flights

Charlotte to Easter Island flights

Other flights to Santiago

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$330+ Cheap flights from Myrtle Beach (MYR) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Myrtle Beach to Santiago with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Myrtle Beach to Santiago

Cheapest flights from Myrtle Beach to SantiagoExplore the most affordable flight options available from Myrtle Beach to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 25, 2025.

Explore the most affordable flight options available from Myrtle Beach to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 25, 2025.

Cheap flight deals from Myrtle Beach to Santiago

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Myrtle Beach to Santiago that are best for you.

Best time to book a flight from Myrtle Beach to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Myrtle Beach with our price prediction graph.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Myrtle Beach to Santiago?

Can I find deals for flights from Myrtle Beach to Santiago that include hotel bookings?

How can I find direct flights from Myrtle Beach to Santiago?

Can I find deals for business class flights from Myrtle Beach to Santiago?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Myrtle Beach to Santiago

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Myrtle Beach to Santiago
Explore the most affordable flight options available from Myrtle Beach to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 25, 2025.