$273+ Cheap flights from Chicago (CHI) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — SCL
Jul 31 — Aug 71
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Chicago to SantiagoExplore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2026.
Explore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:44 pm
ORD
- SCL
2 stops32h 26m
Multiple Airlines
Tue 9/227:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$628
This Kiwi.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:05 am
ORD
- SCL
2 stops19h 51m
Multiple Airlines
Sun 10/257:25 am
SCL
- ORD
1 stop15h 55m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$633
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:59 pm
ORD
- SCL
2 stops32h 01m
Multiple Airlines
Wed 9/237:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$645
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:44 pm
ORD
- SCL
2 stops31h 04m
Multiple Airlines
Fri 11/137:25 am
SCL
- ORD
1 stop15h 55m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$646
This Kiwi.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:05 am
ORD
- SCL
2 stops18h 45m
Multiple Airlines
Tue 9/227:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/27![Multiple Airlines logo]()
$659
This Kiwi.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:44 pm
ORD
- SCL
2 stops29h 02m
Multiple Airlines
Tue 9/227:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/27![Multiple Airlines logo]()
$660
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:26 am
ORD
- SCL
2 stops16h 16m
Multiple Airlines
Sun 11/157:25 am
SCL
- ORD
1 stop15h 55m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$661
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:26 am
ORD
- SCL
2 stops16h 16m
Multiple Airlines
Mon 11/167:25 am
SCL
- ORD
1 stop15h 55m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$662
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:44 pm
ORD
- SCL
2 stops27h 52m
Multiple Airlines
Wed 11/117:25 am
SCL
- ORD
1 stop15h 55m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$671
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:13 pm
ORD
- SCL
2 stops32h 47m
Multiple Airlines
Sat 8/226:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$674
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:13 pm
ORD
- SCL
2 stops31h 37m
Multiple Airlines
Thu 8/276:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$676
This Bravofly deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:46 pm
MDW
- SCL
2 stops17h 09m
LATAM Airlines
Fri 8/2111:05 pm
SCL
- MDW
2 stops35h 54m
LATAM Airlines
Deal found 6/30![LATAM Airlines logo]()
$688
Best flights from Chicago to SantiagoDiscover carefully curated flight deals from Chicago to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 1, 2026.
Discover carefully curated flight deals from Chicago to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 1, 2026.
This Copa Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/263:21 pm
ORD
- SCL
1 stop12h 53m
Copa Airlines
Mon 8/314:14 am
SCL
- ORD
1 stop21h 48m
Copa Airlines
Deal found 6/30![Copa Airlines logo]()
$692
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:25 pm
MDW
- SCL
2 stops17h 40m
Delta
Fri 11/2011:10 pm
SCL
- MDW
1 stop20h 15m
Delta
Deal found 6/30![Delta logo]()
$704
This LATAM Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:15 am
ORD
- SCL
2 stops20h 40m
LATAM Airlines
Sat 10/2411:05 pm
SCL
- ORD
2 stops21h 27m
LATAM Airlines
Deal found 6/26![LATAM Airlines logo]()
$709
This Avianca deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1111:20 pm
ORD
- SCL
1 stop13h 55m
Avianca
Fri 7/246:40 am
SCL
- ORD
1 stop15h 40m
Avianca
Deal found 6/28![Avianca logo]()
$756
This Copa Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:02 am
ORD
- SCL
1 stop13h 41m
Copa Airlines
Mon 8/314:14 am
SCL
- ORD
1 stop21h 48m
Copa Airlines
Deal found 7/1![Copa Airlines logo]()
$692
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:30 pm
ORD
- SCL
1 stop15h 20m
Delta
Mon 12/77:25 pm
SCL
- ORD
2 stops17h 42m
Delta
Deal found 7/1![Delta logo]()
$704
This Cheapflightsfares deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:35 am
MDW
- SCL
2 stops25h 00m
LATAM Airlines
Sun 10/254:00 pm
SCL
- MDW
2 stops32h 10m
LATAM Airlines
Deal found 6/26![LATAM Airlines logo]()
$751
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/139:54 am
ORD
- SCL
2 stops19h 01m
Delta
Thu 8/2010:55 pm
SCL
- ORD
1 stop19h 06m
Delta
Deal found 6/29![Delta logo]()
$704
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:54 am
MDW
- SCL
2 stops19h 01m
Delta
Thu 8/2010:55 pm
SCL
- MDW
2 stops20h 38m
Delta
Deal found 6/29![Delta logo]()
$709
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:46 pm
MDW
- SCL
1 stop17h 29m
Delta
Wed 9/211:00 pm
SCL
- MDW
2 stops18h 15m
Delta
Deal found 7/1![Delta logo]()
$709
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2011:10 am
ORD
- SCL
2 stops17h 45m
Delta
Sun 10/2511:10 pm
SCL
- ORD
2 stops21h 30m
Delta
Deal found 6/26![Delta logo]()
$709
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:15 pm
MDW
- SCL
2 stops17h 50m
Delta
Mon 11/1611:10 pm
SCL
- MDW
1 stop13h 42m
Delta
Deal found 6/30![Delta logo]()
$766
This Delta deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:35 am
MDW
- SCL
1 stop17h 05m
Delta
Wed 11/2511:10 pm
SCL
- MDW
1 stop13h 42m
Delta
Deal found 6/27![Delta logo]()
$766
This Delta deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/314:39 pm
MDW
- SCL
1 stop13h 36m
Delta
Fri 9/48:40 pm
SCL
- MDW
1 stop20h 04m
Delta
Deal found 6/28![Delta logo]()
$766
This Delta deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:33 am
ORD
- SCL
2 stops18h 22m
Delta
Sun 8/911:00 pm
SCL
- ORD
2 stops20h 29m
Delta
Deal found 6/27![Delta logo]()
$771
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/611:30 am
ORD
- SCL
2 stops17h 20m
Delta
Mon 11/1611:10 pm
SCL
- ORD
2 stops20h 27m
Delta
Deal found 6/26![Delta logo]()
$771
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am
ORD
- SCL
1 stop22h 25m
Delta
Sat 9/1910:55 pm
SCL
- ORD
2 stops19h 19m
Delta
Deal found 6/30![Delta logo]()
$771
Last-minute flights from Chicago to SantiagoDiscover last-minute flight deals from Chicago to Santiago. Data last updated July 1, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Santiago. Data last updated July 1, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:16 am
ORD
- SCL
2 stops17h 58m
Multiple Airlines
Mon 8/176:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/27![Multiple Airlines logo]()
$681
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:13 pm
ORD
- SCL
2 stops31h 37m
Multiple Airlines
Thu 8/276:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$676
This Kiwi.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:13 pm
ORD
- SCL
2 stops31h 37m
Multiple Airlines
Thu 8/206:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$678
This Avianca deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1311:20 pm
ORD
- SCL
1 stop13h 55m
Avianca
Thu 8/206:40 am
SCL
- ORD
1 stop15h 40m
Avianca
Deal found 6/29![Avianca logo]()
$689
This Bravofly deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:46 pm
MDW
- SCL
2 stops17h 09m
LATAM Airlines
Fri 8/2111:05 pm
SCL
- MDW
2 stops35h 54m
LATAM Airlines
Deal found 6/30![LATAM Airlines logo]()
$688
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:13 pm
ORD
- SCL
2 stops32h 47m
Multiple Airlines
Sat 8/226:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$674
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:59 pm
ORD
- SCL
2 stops32h 01m
Multiple Airlines
Wed 9/237:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$645
This Copa Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:02 am
ORD
- SCL
1 stop13h 41m
Copa Airlines
Mon 8/314:14 am
SCL
- ORD
1 stop21h 48m
Copa Airlines
Deal found 7/1![Copa Airlines logo]()
$692
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:59 pm
ORD
- SCL
2 stops32h 01m
Multiple Airlines
Mon 8/316:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$646
This Kiwi.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:05 am
ORD
- SCL
2 stops18h 45m
Multiple Airlines
Mon 9/217:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/27![Multiple Airlines logo]()
$659
This LATAM Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:05 am
MDW
- SCL
2 stops30h 30m
LATAM Airlines
Thu 9/311:05 pm
SCL
- MDW
2 stops24h 31m
LATAM Airlines
Deal found 6/29![LATAM Airlines logo]()
$704
This LATAM Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/314:39 pm
MDW
- SCL
2 stops20h 26m
LATAM Airlines
Fri 9/43:20 pm
SCL
- MDW
2 stops19h 50m
LATAM Airlines
Deal found 6/28![LATAM Airlines logo]()
$706
One-way flights from Chicago to SantiagoSearch for one-way flight options from Chicago to Santiago. Find affordable one-way fares based on user searches. Data last updated July 1, 2026.
Search for one-way flight options from Chicago to Santiago. Find affordable one-way fares based on user searches. Data last updated July 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:59 pm
ORD
- SCL
2 stops34h 15m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$273
This Booking.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:45 am
ORD
- SCL
1 stop15h 10m
Arajet
Deal found 6/29![Arajet logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:50 am
MDW
- SCL
3 stops37h 00m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:33 pm
ORD
- SCL
3 stops48h 49m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:03 pm
MDW
- SCL
3 stops38h 52m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:35 am
ORD
- SCL
3 stops43h 20m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/239:29 am
MDW
- SCL
3 stops39h 09m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$365
This KAYAK deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:05 am
ORD
- SCL
1 stop19h 45m
Azul
Deal found 6/29![Azul logo]()
$378
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:05 am
ORD
- SCL
3 stops38h 38m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$379
This Air Canada deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:25 am
ORD
- SCL
2 stops19h 25m
Air Canada
Deal found 6/29![Air Canada logo]()
$382
This Air Canada deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:55 pm
ORD
- SCL
2 stops18h 20m
Air Canada
Deal found 6/29![Air Canada logo]()
$390
This FlightHub deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:46 pm
MDW
- SCL
3 stops23h 39m
LATAM Airlines
Deal found 6/28![LATAM Airlines logo]()
$431
Find flight deals from Chicago to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 1, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $633 (Kiwi.com) |
One-way from | $273 (Kiwi.com) |
Popular in | September |
Cheapest in | March |
Average price | $897 |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2026.
Use the filters below to find and compare flights from Chicago to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Wed 8/26
3:21 pm-5:14 am
1 stop12h 53m
Santiago Arturo Merino Benitez
Mon 8/31
4:14 am-1:02 am
1 stop21h 48m
$692
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Wed 8/19
8:02 am-10:43 pm
1 stop13h 41m
Santiago Arturo Merino Benitez
Mon 8/31
4:14 am-1:02 am
1 stop21h 48m
$692
ChicagoSantiago
MDW - SCL
MDWSCL
Chicago Midway
Thu 11/12
5:25 pm-2:05 pm
2 stops17h 40m
Santiago Arturo Merino Benitez
Fri 11/20
11:10 pm-4:25 pm
1 stop20h 15m
$704
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Tue 11/17
1:30 pm-7:50 am
1 stop15h 20m
Santiago Arturo Merino Benitez
Mon 12/7
7:25 pm-10:07 am
2 stops17h 42m
$704
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Thu 8/13
9:54 am-5:55 am
2 stops19h 01m
Santiago Arturo Merino Benitez
Thu 8/20
10:55 pm-5:01 pm
1 stop19h 06m
$704
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Fri 10/9
8:15 am-6:55 am
2 stops20h 40m
Santiago Arturo Merino Benitez
Sat 10/24
11:05 pm-6:32 pm
2 stops21h 27m
$709
ChicagoSantiago
MDW - SCL
MDWSCL
Chicago Midway
Thu 8/13
10:54 am-6:55 am
2 stops19h 01m
Santiago Arturo Merino Benitez
Thu 8/20
10:55 pm-6:33 pm
2 stops20h 38m
$709
ChicagoSantiago
MDW - SCL
MDWSCL
Chicago Midway
Thu 8/27
12:46 pm-7:15 am
1 stop17h 29m
Santiago Arturo Merino Benitez
Wed 9/2
11:00 pm-4:15 pm
2 stops18h 15m
$709
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Tue 10/20
11:10 am-6:55 am
2 stops17h 45m
Santiago Arturo Merino Benitez
Sun 10/25
11:10 pm-6:40 pm
2 stops21h 30m
$709
ChicagoSantiago
MDW - SCL
MDWSCL
Chicago Midway
Tue 10/20
10:35 am-1:35 pm
2 stops25h 00m
Santiago Arturo Merino Benitez
Sun 10/25
4:00 pm-10:10 pm
2 stops32h 10m
$751
Showing 1-10 of 33 resultsSorted by cheapest first
Compare providers for flights from Chicago to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Santiago in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Chicago-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Chicago-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Chicago-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Chicago to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Chicago with our price prediction graph.
CHI-SCL
ORD-SCL
MDW-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Santiago
CHI-SCL
ORD-SCL
MDW-SCL
What is the cheapest month to book a flight from Chicago to Santiago?
Currently, March is the cheapest month in which you can book a flight from Chicago to Santiago (average of $302). Flying from Chicago to Santiago in November is currently the most expensive (average of $626). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Chicago to Santiago?
What’s the top layover airport for flights from Chicago to Santiago?
Share of 1-stop round-trip flights from Chicago to Santiago chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 83% of 1-stop itineraries from Chicago to Santiago on Cheapflights.
What’s the cheapest layover airport for flights from Chicago to Santiago?
Average round-trip fare for 1-stop flights from Chicago to Santiago, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Bogotá (BOG) is the most affordable 1-stop option, with an average round-trip price of $558.
What’s the fastest layover option from Chicago to Santiago?
Shortest average travel time for 1-stop one-way flights from Chicago to Santiago, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 12h 38m.
Which airport typically offers the quickest layover for flights from Chicago to Santiago?
Average layover duration for 1-stop one-way flights from Chicago to Santiago, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 24m.
How often are flights from Chicago to Santiago delayed?
About 0% of weekly flights between Chicago and Santiago have experienced delays in the past year, with the average delay time being 0 minutes.
What is the most punctual flight time for Chicago to Santiago flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Wednesday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
How far ahead should I book a flight from Chicago to Santiago?
The price you pay for your flight from Chicago to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 88 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated July 1, 2026.
Read through reviews of airlines operating flights from Chicago to Santiago, such as Copa Airlines,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Comfort
7.4
Crew
8.1
Overall
7.6
Entertainment
6.8
Food
6.9
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Boarding
7.8
Comfort
7.4
Crew
8.1
Overall
7.6
Entertainment
6.8
Food
6.9
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Boarding
7.8
Comfort
7.4
Crew
8.1
Overall
7.6
Entertainment
6.8
Food
6.9
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Boarding
7.8
Comfort
7.4
Crew
8.1
Overall
7.6
Entertainment
6.8
Food
6.9
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Boarding
7.8
Comfort
7.4
Crew
8.1
Overall
7.6
Entertainment
6.8
Food
6.9
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Boarding
7.8
Comfort
7.4
Crew
8.1
Overall
7.6
Entertainment
6.8
Food
6.9
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Related info for your journey
Find useful and relevant information for your journey from Chicago to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
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Search flights from Chicago to Santiago by cabin class
Find flights from Chicago to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Santiago flights
Browse other Chicago and Santiago flight options. Last updated on July 1, 2026.
Other flights from Chicago
Browse through other flights departing from Chicago. Flights are based on user searches made on Cheapflights and were last updated on July 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 1, 2026.
Top 6 airlines flying from Chicago to Santiago
Discover the top 6 airlines that operate flights from Chicago to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$537 | Average$700 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$540 | Average$750 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$558 | Average$790 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$597 | Average$887 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$626 | Average$796 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$626 | Average$918 | FlexibilityNo cancel fee | On-timeN/A |