$265+ Cheap flights from Chicago (CHI) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — SCL
Sep 21 — Sep 281
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Chicago to SantiagoExplore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 22, 2026.
Explore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 22, 2026.
This Copa Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:13 pm -
1 stop31h 09m
Sat 10/315:22 am -
1 stop21h 49m
Deal found 8/21![Copa Airlines logo]()
$680
This Priceline deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:05 am -
1 stop20h 45m
Sun 12/67:25 am -
1 stop15h 55m
Deal found 8/18![Multiple Airlines logo]()
$683
This Faresmojo deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:30 am -
1 stop19h 55m
Thu 9/2411:55 pm -
1 stop19h 28m
Deal found 8/18![JetBlue logo]()
$685
This Bravofly deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:30 am -
2 stops17h 05m
Tue 10/138:50 am -
2 stops17h 07m
Deal found 8/22![LATAM Airlines logo]()
$687
This FlightHub deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:32 am -
2 stops16h 03m
Mon 12/711:10 pm -
2 stops16h 10m
Deal found 8/21![LATAM Airlines logo]()
$697
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/143:50 pm -
2 stops44h 45m
Mon 9/2812:22 pm -
1 stop14h 40m
Deal found 8/17![Multiple Airlines logo]()
$700
This Flightnetwork deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:45 am -
1 stop15h 10m
Fri 10/912:23 pm -
1 stop14h 34m
Deal found 8/18![Multiple Airlines logo]()
$711
This FlightHub deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1611:30 am -
2 stops16h 30m
Mon 11/2311:50 pm -
1 stop20h 30m
Deal found 8/20![LATAM Airlines logo]()
$713
This Bravofly deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:04 am -
2 stops21h 31m
Tue 10/1311:55 pm -
2 stops24h 38m
Deal found 8/22![LATAM Airlines logo]()
$716
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:48 am -
2 stops18h 12m
Tue 10/208:40 pm -
1 stop17h 14m
Deal found 8/21![Delta logo]()
$752
This Expedia deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop22h 40m
Sat 12/59:50 pm -
1 stop15h 43m
Deal found 8/19![LATAM Airlines logo]()
$754
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:00 pm -
1 stop17h 15m
Mon 10/128:40 pm -
1 stop15h 23m
Deal found 8/21![Delta logo]()
$756
Best flights from Chicago to SantiagoDiscover carefully curated flight deals from Chicago to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 22, 2026.
Discover carefully curated flight deals from Chicago to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 22, 2026.
This Copa Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:35 am -
1 stop17h 03m
Mon 11/1612:15 pm -
1 stop14h 56m
Deal found 8/17![Copa Airlines logo]()
$744
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:51 pm -
1 stop16h 24m
Tue 10/2011:55 pm -
1 stop20h 25m
Deal found 8/20![Delta logo]()
$748
This Copa Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/82:13 pm -
1 stop27h 02m
Sun 11/1512:15 pm -
1 stop14h 56m
Deal found 8/21![Copa Airlines logo]()
$744
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:48 am -
2 stops18h 12m
Tue 10/208:40 pm -
1 stop17h 14m
Deal found 8/21![Delta logo]()
$752
This Copa Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:35 am -
1 stop13h 44m
Sun 11/225:07 am -
1 stop22h 04m
Deal found 8/20![Copa Airlines logo]()
$744
This Delta deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:09 pm -
1 stop13h 06m
Tue 10/138:40 pm -
1 stop17h 14m
Deal found 8/22![Delta logo]()
$756
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:05 am -
1 stop22h 10m
Fri 10/28:50 am -
2 stops17h 09m
Deal found 8/21![Delta logo]()
$756
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:25 am -
1 stop19h 00m
Mon 10/128:40 pm -
1 stop22h 18m
Deal found 8/21![Delta logo]()
$756
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:48 am -
2 stops16h 47m
Mon 10/128:40 pm -
2 stops18h 07m
Deal found 8/21![Delta logo]()
$761
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:44 am -
1 stop19h 31m
Thu 10/111:55 pm -
2 stops20h 09m
Deal found 8/21![Delta logo]()
$761
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:17 am -
2 stops17h 38m
Sun 10/118:40 pm -
1 stop13h 59m
Deal found 8/20![Delta logo]()
$761
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2011:19 am -
2 stops17h 36m
Fri 10/238:50 am -
2 stops17h 07m
Deal found 8/21![Delta logo]()
$761
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:21 am -
2 stops17h 34m
Wed 10/2112:35 am -
2 stops18h 23m
Deal found 8/21![Delta logo]()
$761
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:59 am -
1 stop19h 16m
Sun 10/2511:10 pm -
1 stop14h 44m
Deal found 8/20![Delta logo]()
$792
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:19 pm -
1 stop12h 21m
Mon 11/1611:10 pm -
1 stop14h 23m
Deal found 8/19![Delta logo]()
$792
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/129:29 am -
2 stops18h 06m
Tue 1/2611:10 pm -
2 stops16h 23m
Deal found 8/21![Delta logo]()
$797
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:28 am -
2 stops16h 32m
Sun 11/2211:10 pm -
2 stops16h 25m
Deal found 8/20![Delta logo]()
$797
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:33 am -
2 stops17h 27m
Tue 10/208:40 pm -
1 stop15h 23m
Deal found 8/19![Delta logo]()
$827
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:10 pm -
1 stop13h 05m
Mon 9/288:40 pm -
1 stop21h 35m
Deal found 8/17![Delta logo]()
$827
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:48 am -
2 stops18h 12m
Wed 9/3012:35 am -
2 stops17h 40m
Deal found 8/19![Delta logo]()
$832
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/131:00 pm -
1 stop14h 40m
Sun 12/2711:00 pm -
2 stops20h 22m
Deal found 8/17![Delta logo]()
$832
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/121:00 pm -
2 stops15h 40m
Tue 1/2611:10 pm -
2 stops16h 23m
Deal found 8/17![Delta logo]()
$832
Last-minute flights from Chicago to SantiagoDiscover last-minute flight deals from Chicago to Santiago. Data last updated August 22, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Santiago. Data last updated August 22, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:44 pm -
2 stops40h 51m
Wed 9/1612:22 pm -
1 stop14h 40m
Deal found 8/21![Multiple Airlines logo]()
$757
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:50 pm -
2 stops37h 35m
Sun 9/205:14 am -
1 stop21h 48m
Deal found 8/20![Multiple Airlines logo]()
$758
This Viajes Falabella deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Viajes Falabella is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:44 am -
2 stops18h 11m
Sun 9/2010:20 am -
2 stops15h 39m
Deal found 8/20![LATAM Airlines logo]()
$759
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/143:50 pm -
2 stops44h 45m
Mon 9/2812:22 pm -
1 stop14h 40m
Deal found 8/17![Multiple Airlines logo]()
$700
This Bravofly deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:10 pm -
1 stop13h 05m
Sun 9/2712:05 am -
2 stops24h 39m
Deal found 8/17![LATAM Airlines logo]()
$803
This FlightHub deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:25 am -
1 stop19h 00m
Thu 9/2411:55 pm -
1 stop19h 04m
Deal found 8/19![LATAM Airlines logo]()
$744
This Faresmojo deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:30 am -
1 stop19h 55m
Thu 9/2411:55 pm -
1 stop19h 28m
Deal found 8/18![JetBlue logo]()
$685
This LATAM Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:30 am -
2 stops30h 55m
Mon 10/511:55 pm -
1 stop19h 25m
Deal found 8/21![LATAM Airlines logo]()
$756
This Travelocity deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:48 am -
3 stops33h 27m
Mon 9/288:40 pm -
1 stop28h 04m
Deal found 8/20![LATAM Airlines logo]()
$795
This SmartFares deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:05 am -
1 stop24h 10m
Tue 9/298:40 pm -
1 stop28h 04m
Deal found 8/19![LATAM Airlines logo]()
$801
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/273:50 pm -
2 stops34h 06m
Thu 10/112:23 pm -
1 stop14h 34m
Deal found 8/21![Multiple Airlines logo]()
$745
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:15 am -
2 stops16h 55m
Thu 10/112:23 pm -
1 stop14h 34m
Deal found 8/21![Multiple Airlines logo]()
$716
One-way flights from Chicago to SantiagoSearch for one-way flight options from Chicago to Santiago. Find affordable one-way fares based on user searches. Data last updated August 22, 2026.
Search for one-way flight options from Chicago to Santiago. Find affordable one-way fares based on user searches. Data last updated August 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:00 am -
3 stops42h 35m
Deal found 8/21![Multiple Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:11 am -
3 stops43h 44m
Deal found 8/19![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:20 pm -
3 stops39h 18m
Deal found 8/21![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/212:20 pm -
3 stops36h 15m
Deal found 8/21![Multiple Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/223:50 pm -
2 stops34h 06m
Deal found 8/17![Multiple Airlines logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:50 pm -
3 stops37h 05m
Deal found 8/17![Multiple Airlines logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:25 am -
3 stops44h 30m
Deal found 8/17![Multiple Airlines logo]()
$336
This Arajet deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:45 am -
1 stop21h 53m
Deal found 8/21![Arajet logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/241:12 pm -
3 stops37h 43m
Deal found 8/20![Multiple Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2412:37 pm -
3 stops38h 18m
Deal found 8/20![Multiple Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2412:44 am -
2 stops44h 59m
Deal found 8/18![Multiple Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/143:50 pm -
3 stops33h 45m
Deal found 8/19![Multiple Airlines logo]()
$354
Find flight deals from Chicago to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 22, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $680 (Copa Airlines) |
One-way from | $265 (Kiwi.com) |
Popular in | July |
Cheapest in | January |
Average price | $831 |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 22, 2026.
Use the filters below to find and compare flights from Chicago to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Fri 11/6
7:35 am-3:38 am
1 stop17h 03m
Santiago Arturo Merino Benitez
Mon 11/16
12:15 pm-12:11 am
1 stop14h 56m
$744
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Sun 11/8
2:13 pm-8:15 pm
1 stop27h 02m
Santiago Arturo Merino Benitez
Sun 11/15
12:15 pm-12:11 am
1 stop14h 56m
$744
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Sat 11/14
7:35 am-12:19 am
1 stop13h 44m
Santiago Arturo Merino Benitez
Sun 11/22
5:07 am-12:11 am
1 stop22h 04m
$744
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Mon 10/5
1:51 pm-8:15 am
1 stop16h 24m
Santiago Arturo Merino Benitez
Tue 10/20
11:55 pm-6:20 pm
1 stop20h 25m
$748
ChicagoSantiago
MDW Chicago Midway - SCL Santiago Arturo Merino Benitez
MDWSCL
Chicago Midway
Mon 10/5
10:48 am-7:00 am
2 stops18h 12m
Santiago Arturo Merino Benitez
Tue 10/20
8:40 pm-11:54 am
1 stop17h 14m
$752
ChicagoSantiago
MDW Chicago Midway - SCL Santiago Arturo Merino Benitez
MDWSCL
Chicago Midway
Tue 10/6
5:09 pm-8:15 am
1 stop13h 06m
Santiago Arturo Merino Benitez
Tue 10/13
8:40 pm-11:54 am
1 stop17h 14m
$756
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Tue 9/29
8:05 am-8:15 am
1 stop22h 10m
Santiago Arturo Merino Benitez
Fri 10/2
8:50 am-11:59 pm
2 stops17h 09m
$756
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Mon 10/5
10:25 am-7:25 am
1 stop19h 00m
Santiago Arturo Merino Benitez
Mon 10/12
8:40 pm-4:58 pm
1 stop22h 18m
$756
ChicagoSantiago
MDW Chicago Midway - SCL Santiago Arturo Merino Benitez
MDWSCL
Chicago Midway
Mon 10/5
10:48 am-5:35 am
2 stops16h 47m
Santiago Arturo Merino Benitez
Mon 10/12
8:40 pm-12:47 pm
2 stops18h 07m
$761
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Tue 9/29
10:44 am-8:15 am
1 stop19h 31m
Santiago Arturo Merino Benitez
Thu 10/1
11:55 pm-6:04 pm
2 stops20h 09m
$761
Showing 1-10 of 43 resultsSorted by cheapest first
Compare providers for flights from Chicago to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Santiago in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Chicago-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Chicago-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Chicago-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Chicago to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Chicago with our price prediction graph.
CHI-SCL
ORD-SCL
MDW-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Santiago
CHI-SCL
ORD-SCL
MDW-SCL
What is the cheapest month to book a flight from Chicago to Santiago?
Currently, June is the cheapest month in which you can book a flight from Chicago to Santiago (average of $694). Flying from Chicago to Santiago in July is currently the most expensive (average of $1,093). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Chicago to Santiago?
Airfare is below average for this route at the moment.
Chicago to Santiago flights typically cost between $770 and $982 in October.The cheapest round-trip price found within the last 5 days was $680 on Copa Airlines (Oct 26-Oct 31).
What’s the top layover airport for flights from Chicago to Santiago?
Share of 1-stop round-trip flights from Chicago to Santiago chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 71% of 1-stop itineraries from Chicago to Santiago on Cheapflights.
What’s the cheapest layover airport for flights from Chicago to Santiago?
Average round-trip fare for 1-stop flights from Chicago to Santiago, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Bogotá (BOG) is the most affordable 1-stop option, with an average round-trip price of $558.
What’s the fastest layover option from Chicago to Santiago?
Shortest average travel time for 1-stop one-way flights from Chicago to Santiago, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 12h 38m.
Which airport typically offers the quickest layover for flights from Chicago to Santiago?
Average layover duration for 1-stop one-way flights from Chicago to Santiago, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 24m.
How often are flights from Chicago to Santiago delayed?
About 0% of weekly flights between Chicago and Santiago have experienced delays in the past year, with the average delay time being 0 minutes.
What is the most punctual flight time for Chicago to Santiago flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Wednesday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
How far ahead should I book a flight from Chicago to Santiago?
The price you pay for your flight from Chicago to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 85 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated August 22, 2026.
Read through reviews of airlines operating flights from Chicago to Santiago, such as Copa Airlines,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Comfort
7.4
Crew
8.1
Food
6.9
Overall
7.6
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.8
Comfort
7.4
Crew
8.1
Food
6.9
Overall
7.6
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.8
Comfort
7.4
Crew
8.1
Food
6.9
Overall
7.6
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.8
Comfort
7.4
Crew
8.1
Food
6.9
Overall
7.6
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.8
Comfort
7.4
Crew
8.1
Food
6.9
Overall
7.6
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.8
Comfort
7.4
Crew
8.1
Food
6.9
Overall
7.6
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Chicago to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Search flights from Chicago to Santiago by cabin class
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Chicago and Santiago flights
Browse other Chicago and Santiago flight options. Last updated on August 22, 2026.
Other flights from Chicago
Browse through other flights departing from Chicago. Flights are based on user searches made on Cheapflights and were last updated on August 22, 2026.
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Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 22, 2026.
Top 6 airlines flying from Chicago to Santiago
Discover the top 6 airlines that operate flights from Chicago to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$537 | Average$700 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$540 | Average$772 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$546 | Average$895 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$558 | Average$819 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$597 | Average$899 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$626 | Average$788 | FlexibilityNo cancel fee | On-time69% |