$324+ Cheap flights from Chicago (CHI) to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/26. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — SCL
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Chicago to Santiago
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Cheapest flights from Chicago to SantiagoExplore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:45 am -
1 stop21h 53m
Tue 12/18:35 pm -
2 stops28h 38m
Deal found 9/11![Multiple Airlines logo]()
$733
This Arajet deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:45 am -
1 stop21h 53m
Thu 12/310:00 am -
1 stop15h 40m
Deal found 9/12![Arajet logo]()
$743
This FlightHub deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:30 am -
1 stop18h 55m
Sun 10/2510:50 pm -
1 stop20h 30m
Deal found 9/10![LATAM Airlines logo]()
$746
This FlightHub deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:30 am -
2 stops17h 30m
Mon 12/711:10 pm -
2 stops16h 10m
Deal found 9/10![LATAM Airlines logo]()
$751
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:30 am -
2 stops17h 30m
Thu 12/1011:10 pm -
2 stops16h 10m
Deal found 9/11![LATAM Airlines logo]()
$752
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:13 pm -
1 stop12h 42m
Mon 11/212:15 pm -
1 stop14h 56m
Deal found 9/11![Copa Airlines logo]()
$753
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:45 am -
1 stop21h 53m
Wed 11/258:35 pm -
2 stops28h 38m
Deal found 9/11![Multiple Airlines logo]()
$757
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:05 am -
1 stop20h 45m
Fri 12/114:15 pm -
1 stop31h 15m
Deal found 9/14![Multiple Airlines logo]()
$762
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:35 am -
1 stop17h 03m
Mon 11/1612:15 pm -
1 stop14h 56m
Deal found 9/10![Copa Airlines logo]()
$765
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:30 am -
3 stops32h 30m
Fri 11/132:10 am -
1 stop21h 20m
Deal found 9/14![Multiple Airlines logo]()
$766
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:45 am -
1 stop21h 53m
Mon 11/308:35 pm -
2 stops28h 38m
Deal found 9/11![Multiple Airlines logo]()
$767
This LATAM Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:49 pm -
2 stops31h 01m
Sun 11/111:10 pm -
1 stop14h 33m
Deal found 9/9![LATAM Airlines logo]()
$812
Best flights from Chicago to SantiagoDiscover carefully curated flight deals from Chicago to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Chicago to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:35 am -
1 stop17h 03m
Mon 11/1612:15 pm -
1 stop14h 56m
Deal found 9/13![Copa Airlines logo]()
$765
This Arajet deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/265:45 am -
1 stop21h 53m
Thu 3/410:00 am -
1 stop15h 40m
Deal found 9/12![Arajet logo]()
$811
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:49 pm -
2 stops16h 06m
Wed 10/2111:55 pm -
2 stops18h 19m
Deal found 9/10![Delta logo]()
$817
This Copa Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:13 pm -
1 stop30h 26m
Wed 11/412:15 pm -
1 stop27h 31m
Deal found 9/13![Copa Airlines logo]()
$765
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:49 pm -
2 stops16h 06m
Wed 10/2112:35 am -
2 stops17h 39m
Deal found 9/10![Delta logo]()
$817
This Arajet deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/15:45 am -
1 stop21h 53m
Sun 1/245:00 am -
1 stop19h 20m
Deal found 9/14![Arajet logo]()
$871
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:49 pm -
2 stops16h 06m
Tue 10/208:40 pm -
1 stop27h 53m
Deal found 9/10![Delta logo]()
$825
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:59 am -
2 stops18h 01m
Wed 11/411:10 pm -
1 stop19h 07m
Deal found 9/13![Delta logo]()
$837
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:49 pm -
1 stop17h 26m
Sat 10/248:40 pm -
1 stop15h 23m
Deal found 9/10![Delta logo]()
$865
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:30 am -
1 stop19h 55m
Fri 10/238:50 am -
2 stops17h 07m
Deal found 9/10![Delta logo]()
$865
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:29 am -
2 stops19h 26m
Wed 10/2111:55 pm -
2 stops20h 05m
Deal found 9/10![Delta logo]()
$870
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/61:23 pm -
1 stop16h 52m
Mon 10/198:40 pm -
2 stops15h 49m
Deal found 9/10![Delta logo]()
$870
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/711:19 am -
2 stops17h 36m
Wed 10/148:40 pm -
2 stops23h 49m
Deal found 9/10![Delta logo]()
$870
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:48 am -
2 stops18h 12m
Sun 10/48:55 pm -
2 stops21h 16m
Deal found 9/14![Delta logo]()
$885
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:06 pm -
1 stop13h 09m
Mon 11/211:10 pm -
1 stop19h 07m
Deal found 9/13![Delta logo]()
$885
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:48 am -
2 stops16h 52m
Fri 9/258:40 pm -
1 stop20h 44m
Deal found 9/12![Delta logo]()
$885
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/221:00 pm -
1 stop17h 15m
Thu 9/248:40 pm -
1 stop15h 09m
Deal found 9/12![Delta logo]()
$885
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/19:00 am -
1 stop19h 40m
Sun 1/248:13 am -
2 stops18h 37m
Deal found 9/13![Delta logo]()
$885
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/3011:10 am -
1 stop16h 30m
Wed 2/1011:10 pm -
1 stop17h 10m
Deal found 9/10![Delta logo]()
$885
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/231:30 pm -
1 stop14h 25m
Mon 3/111:50 pm -
1 stop15h 46m
Deal found 9/12![Delta logo]()
$885
Last-minute flights from Chicago to SantiagoDiscover last-minute flight deals from Chicago to Santiago. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Santiago. Data last updated September 15, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:30 am -
3 stops32h 30m
Fri 11/132:10 am -
1 stop21h 20m
Deal found 9/14![Multiple Airlines logo]()
$766
This FlightHub deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:48 am -
2 stops16h 47m
Mon 11/27:40 am -
2 stops17h 53m
Deal found 9/13![LATAM Airlines logo]()
$854
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:49 pm -
2 stops16h 06m
Sat 10/248:40 pm -
1 stop17h 14m
Deal found 9/10![Delta logo]()
$817
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:49 pm -
2 stops16h 06m
Tue 10/208:40 pm -
1 stop27h 53m
Deal found 9/10![Delta logo]()
$825
This FlightHub deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:30 am -
1 stop18h 55m
Sun 10/2510:50 pm -
1 stop20h 30m
Deal found 9/10![LATAM Airlines logo]()
$746
This LATAM Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:50 pm -
1 stop15h 35m
Thu 10/2211:55 pm -
1 stop19h 25m
Deal found 9/12![LATAM Airlines logo]()
$796
This Cheapflightsfares deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:09 pm -
1 stop13h 06m
Sun 10/258:13 am -
2 stops27h 50m
Deal found 9/12![LATAM Airlines logo]()
$859
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:03 pm -
2 stops15h 42m
Sat 10/3110:15 pm -
2 stops17h 25m
Deal found 9/12![American Airlines logo]()
$782
This Justfly.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:30 am -
1 stop17h 25m
Sun 11/811:10 pm -
2 stops16h 10m
Deal found 9/10![LATAM Airlines logo]()
$751
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:13 pm -
1 stop12h 42m
Mon 11/212:15 pm -
1 stop14h 56m
Deal found 9/11![Copa Airlines logo]()
$753
This LATAM Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:49 pm -
2 stops31h 01m
Sun 11/111:10 pm -
1 stop14h 33m
Deal found 9/9![LATAM Airlines logo]()
$812
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:59 am -
2 stops18h 01m
Wed 11/411:10 pm -
1 stop19h 07m
Deal found 9/13![Delta logo]()
$837
One-way flights from Chicago to SantiagoSearch for one-way flight options from Chicago to Santiago. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from Chicago to Santiago. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:15 am -
3 stops43h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:41 pm -
3 stops34h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$326
This Arajet deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:45 am -
1 stop21h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Arajet logo]()
$339
This Booking.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/225:45 am -
1 stop21h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Arajet logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:21 am -
3 stops44h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:44 pm -
3 stops53h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$373
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:25 am -
3 stops42h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:12 pm -
2 stops27h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$382
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:44 pm -
3 stops55h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$390
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:50 pm -
3 stops28h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:42 pm -
3 stops30h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$401
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:25 am -
3 stops42h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$409
Find flight deals from Chicago to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $733 (Kiwi.com) |
One-way from | $324 (Kiwi.com) |
Popular in | July |
Cheapest in | March |
Average price | $979 |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Chicago to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Fri 11/13
5:45 am-6:38 am
1 stop21h 53m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$339
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Mon 10/5
7:25 am-3:35 am
3 stops42h 10m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$375
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Fri 10/23
7:44 pm-4:55 am
3 stops55h 11m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$390
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Wed 1/6
6:29 am-10:53 am
2 stops49h 24m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$428
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Thu 12/24
9:21 pm-6:38 am
3 stops30h 17m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$430
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Thu 9/24
11:15 am-2:35 pm
2 stops25h 20m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$434
ChicagoSantiago
MDW Chicago Midway - SCL Santiago Arturo Merino Benitez
MDWSCL
Chicago Midway
Sun 10/4
6:25 am-2:46 am
3 stops42h 21m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$440
ChicagoSantiago
MDW Chicago Midway - SCL Santiago Arturo Merino Benitez
MDWSCL
Chicago Midway
Wed 10/28
6:42 pm-12:22 am
3 stops27h 40m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$451
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Thu 3/4
7:05 am-6:50 am
1 stop20h 45m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$483
ChicagoSantiago
ORD Chicago O'Hare Intl - SCL Santiago Arturo Merino Benitez
ORDSCL
Chicago O'Hare Intl
Tue 10/27
9:51 am-5:55 am
2 stops18h 04m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$487
Showing 1-10 of 38 resultsSorted by cheapest first
Compare providers for flights from Chicago to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Santiago in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Chicago-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Chicago-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Chicago-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Chicago to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Chicago with our price prediction graph.
CHI-SCL
ORD-SCL
MDW-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Santiago
CHI-SCL
ORD-SCL
MDW-SCL
What is the cheapest month to book a flight from Chicago to Santiago?
Currently, June is the cheapest month in which you can book a flight from Chicago to Santiago (average of $694). Flying from Chicago to Santiago in July is currently the most expensive (average of $1,093). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Chicago to Santiago?
Airfare is below average for this route at the moment.
Chicago to Santiago flights typically cost between $759 and $1,080 in November.The cheapest round-trip price found within the last 5 days was $733 on Multiple Airlines (Nov 6-Dec 1).
What’s the top layover airport for flights from Chicago to Santiago?
Share of 1-stop round-trip flights from Chicago to Santiago chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 80% of 1-stop itineraries from Chicago to Santiago on Cheapflights.
What’s the cheapest layover airport for flights from Chicago to Santiago?
Average round-trip fare for 1-stop flights from Chicago to Santiago, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Bogotá (BOG) is the most affordable 1-stop option, with an average round-trip price of $558.
What’s the fastest layover option from Chicago to Santiago?
Shortest average travel time for 1-stop one-way flights from Chicago to Santiago, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 12h 38m.
Which airport typically offers the quickest layover for flights from Chicago to Santiago?
Average layover duration for 1-stop one-way flights from Chicago to Santiago, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 16m.
How often are flights from Chicago to Santiago delayed?
About 0% of weekly flights between Chicago and Santiago have experienced delays in the past year, with the average delay time being 0 minutes.
What is the most punctual flight time for Chicago to Santiago flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Wednesday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
How far ahead should I book a flight from Chicago to Santiago?
The price you pay for your flight from Chicago to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 87 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 15, 2026.
Read through reviews of airlines operating flights from Chicago to Santiago, such as Copa Airlines,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.9
Overall
7.6
Crew
8.1
Boarding
7.8
Comfort
7.4
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Overall
7.6
Crew
8.1
Boarding
7.8
Comfort
7.4
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Overall
7.6
Crew
8.1
Boarding
7.8
Comfort
7.4
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Overall
7.6
Crew
8.1
Boarding
7.8
Comfort
7.4
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Overall
7.6
Crew
8.1
Boarding
7.8
Comfort
7.4
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Overall
7.6
Crew
8.1
Boarding
7.8
Comfort
7.4
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Chicago to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Search flights from Chicago to Santiago by cabin class
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Chicago and Santiago flights
Browse other Chicago and Santiago flight options. Last updated on September 15, 2026.
Other flights from Chicago
Browse through other flights departing from Chicago. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
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Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Top 6 airlines flying from Chicago to Santiago
Discover the top 6 airlines that operate flights from Chicago to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$501 | Average$894 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$537 | Average$709 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$540 | Average$782 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$558 | Average$819 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$597 | Average$1,003 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$626 | Average$786 | FlexibilityNo cancel fee | On-time69% |