How long is the flight from Chicago to Santiago?

LATAM Airlines can get you from Chicago to Santiago in just under 13h 35m. Your travel time can differ by up to . Airlines will cover a distance of 5301 mi.

What are the cheapest airlines flying from Chicago to Santiago round-trip?

According to our current data, Copa Airlines ($511), Avianca ($539), and LATAM Airlines ($694) offers the cheapest pricing from Chicago to Santiago. Copa Airlines is 40% cheaper than the average price of flights available within the next 90 days to this destination.

What is the cheapest day to fly from Chicago to Santiago?

Travelers seeking maximum savings on their Chicago to Santiago flight should consider departing on Monday at noon when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

What are the most popular airlines that fly from Chicago to Santiago?

When booking a flight from Chicago to Santiago, you may want to consider flying on American Airlines, Air Canada or Avianca as they are the most popular for this route.

What is the cheapest day to fly round-trip from Chicago to Santiago?

Sunday is generally a great day to depart. Flying on this day could help you save up to 17%.

How far in advance should I book a flight from Chicago to Santiago?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 23 days in advance, which can save you up to 27% on flights from Chicago to Santiago compared to booking the week you need them. Waiting 23 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $547. For sooner than that we have options available in the next 3 days from $866.

What is the cheapest month to fly from Chicago to Santiago?

Due to multiple factors, expect to potentially pay more when booking in December. For low rates, April can be a great choice for travel to Santiago. Flights to Santiago from Chicago in April are about $864 on average during April, but can be found for as low as $604.

What airport do you fly into for flights to Santiago from Chicago?

For a flight from Chicago to Santiago, you will be flying into Arturo Merino Benitez. Santiago Arturo Merino Benitez (SCL) is just 8.4 mi from the center of the city. Arturo Merino Benitez is the only Santiago airport and it handles 0 inbound flights from Chicago per day. 7 airlines have flights to Santiago Arturo Merino Benitez from Chicago on a regular basis.

Can I find deals for flights from Chicago to Santiago that include hotel bookings?

Yes. In addition to deals on Chicago to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Chicago to Santiago?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Santiago.

Can I find deals for business class flights from Chicago to Santiago?

Yes. Cheapflights offers flight deals from Chicago to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$285+ Cheap Flights from Chicago to Santiago

Q: How much does it cost to fly round-trip from Chicago to Santiago?

Airfare is below average for this route at the moment. Chicago to Santiago flights typically cost between $669 and $903 in September. The cheapest round-trip price found within the last 3 days was $611 on Multiple Airlines (Sep 26-Oct 8).

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Chicago to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Chicago to Santiago Arturo Merino Benitez are usually found in April or May, booked 22 days in advance, depart on a Monday or Wednesday and return on a Monday

Cheap flight deals from Chicago to Santiago

Round-trip from	$611 (Kiwi.com)
One-way from	$285 (Kiwi.com)
Popular in	December
Cheapest in	April
Average price	$803

From Chicago (CHI) to Santiago Arturo Merino Benitez

Search Deals

One-way flight from Chicago (CHI) to Santiago Arturo Merino Benitez

Search Deals

Highest demand for flights based on searches. 13% potential increase in price ($138 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($38 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in August 2025

Search Deals

Find flight deals from Chicago to Santiago

Cheapest flights from Chicago to Santiago
Explore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 18, 2025.

vie. 9/2610:27 amORD - SCL

2 stops22h 53mMultiple Airlines

mié. 10/811:00 amSCL - ORD

1 stop24h 22mMultiple Airlines

Deal found 8/15

$611

lun. 9/810:27 amORD - SCL

2 stops39h 08mMultiple Airlines

lun. 9/2211:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/18

$625

mié. 10/110:27 amORD - SCL

2 stops39h 08mMultiple Airlines

mié. 10/811:00 amSCL - ORD

1 stop24h 22mMultiple Airlines

Deal found 8/16

$628

mié. 9/2410:27 amORD - SCL

2 stops39h 08mMultiple Airlines

mar. 9/3011:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/17

$639

mié. 10/110:27 amORD - SCL

2 stops39h 08mMultiple Airlines

mié. 10/1511:00 amSCL - ORD

1 stop24h 22mMultiple Airlines

Deal found 8/16

$642

mar. 9/95:17 pmORD - SCL

2 stops33h 58mMultiple Airlines

lun. 9/2211:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/18

$644

mar. 9/166:30 amORD - SCL

2 stops20h 45mMultiple Airlines

jue. 9/2511:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/17

$646

jue. 10/28:49 pmORD - SCL

2 stops30h 26mMultiple Airlines

jue. 10/911:00 amSCL - ORD

1 stop24h 22mMultiple Airlines

Deal found 8/17

$648

dom. 9/76:30 amORD - SCL

2 stops20h 45mMultiple Airlines

lun. 9/2211:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/18

$652

dom. 9/1410:13 amMDW - SCL

2 stops17h 02mMultiple Airlines

dom. 9/2110:45 amSCL - MDW

1 stop22h 38mMultiple Airlines

Deal found 8/16

$653

dom. 9/148:49 pmORD - SCL

2 stops30h 26mMultiple Airlines

dom. 9/2111:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/16

$655

jue. 9/118:49 pmORD - SCL

2 stops30h 26mMultiple Airlines

lun. 9/2211:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/18

$658

Best flights from Chicago to Santiago
Discover carefully curated flight deals from Chicago to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated agosto 18, 2025.

vie. 9/2610:27 amORD - SCL

2 stops22h 53mMultiple Airlines

mié. 10/811:00 amSCL - ORD

1 stop24h 22mMultiple Airlines

Deal found 8/15

$611

lun. 9/14:25 pmMDW - SCL

1 stop13h 35mLATAM Airlines

jue. 9/412:10 pmSCL - MDW

2 stops22h 26mLATAM Airlines

Deal found 8/18

$691

lun. 9/810:27 amORD - SCL

2 stops39h 08mMultiple Airlines

lun. 9/2211:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/18

$625

mié. 9/1010:27 amORD - SCL

2 stops39h 08mMultiple Airlines

lun. 9/2211:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/18

$625

mié. 10/110:27 amORD - SCL

2 stops39h 08mMultiple Airlines

mié. 10/811:00 amSCL - ORD

1 stop24h 22mMultiple Airlines

Deal found 8/16

$628

sáb. 8/3010:31 amMDW - SCL

2 stops19h 19mLATAM Airlines

mar. 9/212:10 pmSCL - MDW

2 stops22h 26mLATAM Airlines

Deal found 8/17

$760

mié. 9/2410:27 amORD - SCL

2 stops39h 08mMultiple Airlines

mar. 9/3011:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/17

$639

mié. 9/246:30 pmMDW - SCL

2 stops16h 50mLATAM Airlines

mar. 9/305:55 pmSCL - MDW

2 stops19h 53mLATAM Airlines

Deal found 8/16

$777

mié. 10/110:27 amORD - SCL

2 stops39h 08mMultiple Airlines

mié. 10/1511:00 amSCL - ORD

1 stop24h 22mMultiple Airlines

Deal found 8/16

$642

mié. 10/16:30 pmMDW - SCL

2 stops16h 50mLATAM Airlines

mié. 10/85:55 pmSCL - MDW

2 stops17h 45mLATAM Airlines

Deal found 8/16

$777

mar. 9/2312:43 pmMDW - SCL

1 stop16h 17mLATAM Airlines

lun. 9/295:55 pmSCL - MDW

2 stops19h 53mLATAM Airlines

Deal found 8/17

$777

sáb. 9/135:17 pmORD - SCL

2 stops33h 58mMultiple Airlines

lun. 9/2211:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/18

$644

Last-minute flights from Chicago to Santiago
Discover last-minute flight deals from Chicago to Santiago. Data last updated agosto 18, 2025 and is based on user searches.

dom. 9/76:30 amORD - SCL

2 stops20h 45mMultiple Airlines

lun. 9/2211:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/18

$652

lun. 9/810:27 amORD - SCL

2 stops39h 08mMultiple Airlines

lun. 9/2211:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/18

$625

mar. 9/95:17 pmORD - SCL

2 stops33h 58mMultiple Airlines

lun. 9/2211:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/18

$644

jue. 9/118:49 pmORD - SCL

2 stops30h 26mMultiple Airlines

lun. 9/2211:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/18

$658

dom. 9/1410:13 amMDW - SCL

2 stops17h 02mMultiple Airlines

dom. 9/2110:45 amSCL - MDW

1 stop22h 38mMultiple Airlines

Deal found 8/16

$653

dom. 9/148:49 pmORD - SCL

2 stops30h 26mMultiple Airlines

dom. 9/2111:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/16

$655

dom. 9/142:35 pmORD - SCL

1 stop12h 40mMultiple Airlines

sáb. 9/207:10 amSCL - ORD

2 stops28h 08mMultiple Airlines

Deal found 8/16

$659

mar. 9/166:30 amORD - SCL

2 stops20h 45mMultiple Airlines

jue. 9/2511:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/17

$646

mar. 9/166:30 amORD - SCL

2 stops20h 45mMultiple Airlines

lun. 9/2211:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/16

$661

mar. 9/166:30 amORD - SCL

2 stops20h 45mMultiple Airlines

mar. 9/2311:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/18

$663

mié. 9/2410:27 amORD - SCL

2 stops39h 08mMultiple Airlines

mar. 9/3011:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Deal found 8/17

$639

vie. 9/2610:27 amORD - SCL

2 stops22h 53mMultiple Airlines

mié. 10/811:00 amSCL - ORD

1 stop24h 22mMultiple Airlines

Deal found 8/15

$611

One-way flights from Chicago to Santiago
Search for one-way flight options from Chicago to Santiago. Find affordable one-way fares based on user searches. Data last updated agosto 18, 2025.

sáb. 9/2710:27 amORD - SCL

2 stops41h 33mMultiple Airlines

Deal found 8/16

$285

mié. 10/110:27 amORD - SCL

2 stops39h 08mMultiple Airlines

Deal found 8/17

$291

dom. 11/165:25 amORD - SCL

2 stops21h 05mMultiple Airlines

Deal found 8/17

$304

lun. 9/298:19 amMDW - SCL

2 stops18h 56mMultiple Airlines

Deal found 8/16

$308

jue. 10/28:49 pmORD - SCL

2 stops30h 26mMultiple Airlines

Deal found 8/17

$309

dom. 9/288:49 pmORD - SCL

2 stops30h 26mMultiple Airlines

Deal found 8/17

$311

lun. 9/2911:36 amORD - SCL

3 stops32h 39mMultiple Airlines

Deal found 8/16

$312

mar. 10/76:00 amORD - SCL

2 stops21h 15mMultiple Airlines

Deal found 8/18

$324

vie. 10/39:48 amMDW - SCL

2 stops26h 37mMultiple Airlines

Deal found 8/17

$358

jue. 10/21:49 pmMDW - SCL

3 stops30h 21mMultiple Airlines

Deal found 8/17

$406

dom. 9/2812:43 pmMDW - SCL

1 stop16h 17mDelta

Deal found 8/16

$433

mar. 10/712:48 pmMDW - SCL

2 stops16h 02mLATAM Airlines

Deal found 8/18

$461

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

vie. 9/26

10:27 am-11:20 am

2 stops22h 53m

Santiago Arturo Merino Benitez

mié. 10/8

11:00 am-9:22 am

1 stop24h 22m

$611

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

lun. 9/8

10:27 am-3:35 am

2 stops39h 08m

Santiago Arturo Merino Benitez

lun. 9/22

11:00 am-9:18 am

1 stop24h 18m

$625

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

mié. 9/10

10:27 am-3:35 am

2 stops39h 08m

Santiago Arturo Merino Benitez

lun. 9/22

11:00 am-9:18 am

1 stop24h 18m

$625

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

mié. 10/1

10:27 am-3:35 am

2 stops39h 08m

Santiago Arturo Merino Benitez

mié. 10/8

11:00 am-9:22 am

1 stop24h 22m

$628

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

mié. 9/24

10:27 am-3:35 am

2 stops39h 08m

Santiago Arturo Merino Benitez

mar. 9/30

11:00 am-9:18 am

1 stop24h 18m

$639

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

mié. 10/1

10:27 am-3:35 am

2 stops39h 08m

Santiago Arturo Merino Benitez

mié. 10/15

11:00 am-9:22 am

1 stop24h 22m

$642

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

sáb. 9/13

5:17 pm-5:15 am

2 stops33h 58m

Santiago Arturo Merino Benitez

lun. 9/22

11:00 am-9:18 am

1 stop24h 18m

$644

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

mar. 9/9

5:17 pm-5:15 am

2 stops33h 58m

Santiago Arturo Merino Benitez

lun. 9/22

11:00 am-9:18 am

1 stop24h 18m

$644

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

mar. 9/16

6:30 am-5:15 am

2 stops20h 45m

Santiago Arturo Merino Benitez

jue. 9/25

11:00 am-9:18 am

1 stop24h 18m

$646

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

jue. 10/2

8:49 pm-5:15 am

2 stops30h 26m

Santiago Arturo Merino Benitez

jue. 10/9

11:00 am-9:22 am

1 stop24h 22m

$648

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Showing 1-10 of 33 results

Best time to book a flight from Chicago to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Chicago with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Santiago

How far ahead should I book a flight from Chicago to Santiago?

The price you pay for your flight from Chicago to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 22 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Chicago to Santiago?

Currently, April is the cheapest month in which you can book a flight from Chicago to Santiago (average of $752). Flying from Chicago to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to SCL?

When flying from Chicago to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 11% versus a flight in the afternoon.

How much does it cost to fly round-trip from Chicago to Santiago?

Reviews of airlines servicing Santiago

Read through reviews of airlines operating flights from Chicago to Santiago, such as Delta, LATAM Airlines, and Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,981 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

LATAM Airlines

7.5

Good

1,844 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Copa Airlines

7.5

Good

1,510 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Avianca

6.7

Okay

2,407 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airport do you fly into for flights to Santiago from Chicago?
For a flight from Chicago to Santiago, you will be flying into Arturo Merino Benitez. Santiago Arturo Merino Benitez (SCL) is just 8.4 mi from the center of the city. Arturo Merino Benitez is the only Santiago airport and it handles 0 inbound flights from Chicago per day. 7 airlines have flights to Santiago Arturo Merino Benitez from Chicago on a regular basis.
How long is the flight from Chicago to Santiago?
LATAM Airlines can get you from Chicago to Santiago in just under 13h 35m. Your travel time can differ by up to . Airlines will cover a distance of 5301 mi.
What are the cheapest airlines flying from Chicago to Santiago round-trip?
According to our current data, Copa Airlines ($511), Avianca ($539), and LATAM Airlines ($694) offers the cheapest pricing from Chicago to Santiago. Copa Airlines is 40% cheaper than the average price of flights available within the next 90 days to this destination.
Can I find deals for flights from Chicago to Santiago that include hotel bookings?
Yes. In addition to deals on Chicago to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Chicago to Santiago?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Santiago.
Can I find deals for business class flights from Chicago to Santiago?
Yes. Cheapflights offers flight deals from Chicago to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Chicago to Santiago?
Currently, April is the cheapest month in which you can book a flight from Chicago to Santiago (average of $752). Flying from Chicago to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Chicago to Santiago

O'Hare Intl to Santiago flights

Midway to Santiago flights

St. Louis to Santiago flights

O'Hare Intl to Easter Island flights

O'Hare Intl to Punta Arenas flights

St. Louis to Easter Island flights

Moline to Santiago flights

O'Hare Intl to Antofagasta flights

O'Hare Intl to Arica flights

O'Hare Intl to Balmaceda flights

O'Hare Intl to Concepción flights

O'Hare Intl to Calama flights

Other flights to Santiago

Top 7 airlines flying from Chicago to Santiago

Airline	Cheapest	Average	Flexibility	On-time
Copa Airlines	Cheapest$511	Average$881	FlexibilityNo cancel fee	On-time70%
Avianca	Cheapest$539	Average$726	FlexibilityNo cancel fee	On-time71%
LATAM Airlines	Cheapest$694	Average$1,057	FlexibilityNo cancel fee	On-time81%
Delta	Cheapest$698	Average$933	FlexibilityNo cancel fee	On-timeN/A
Air Canada	Cheapest$707	Average$951	FlexibilityNo cancel fee	On-time67%
American Airlines	Cheapest$750	Average$972	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$782	Average$990	FlexibilityNo cancel fee	On-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$285+ Cheap flights from Chicago (CHI) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Chicago to Santiago with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Chicago to Santiago Arturo Merino Benitez are usually found in April or May, booked 22 days in advance, depart on a Monday or Wednesday and return on a Monday

Cheap flight deals from Chicago to Santiago

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Chicago to Santiago

Cheapest flights from Chicago to SantiagoExplore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 18, 2025.

Explore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 18, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Chicago to Santiago that are best for you.

Best time to book a flight from Chicago to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Chicago with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Santiago

How far ahead should I book a flight from Chicago to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Chicago to Santiago. Price data was last updated on August 8, 2025.

What is the cheapest month to book a flight from Chicago to Santiago?

What is the cheapest time of day to fly from CHI to SCL?

Find hourly flight availability from Chicago to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 18, 2025.

How much does it cost to fly round-trip from Chicago to Santiago?

Reviews of airlines servicing Santiago

Read through reviews of airlines operating flights from Chicago to Santiago, such as Delta, LATAM Airlines, and Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Chicago to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santiago from Chicago?

How long is the flight from Chicago to Santiago?

What are the cheapest airlines flying from Chicago to Santiago round-trip?

Can I find deals for flights from Chicago to Santiago that include hotel bookings?

How can I find direct flights from Chicago to Santiago?

Can I find deals for business class flights from Chicago to Santiago?

What is the cheapest month to book a flight from Chicago to Santiago?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Chicago to Santiago

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from Chicago to Santiago

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Chicago to Santiago
Explore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 18, 2025.