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$263+ Cheap flights from Chicago (CHI) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — SCL
Nov 21 — Nov 281
Fri 11/21
Fri 11/28
1 adult, Economy
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Cheapflights Tip: The best prices from Chicago to Santiago Arturo Merino Benitez are usually found in September or April, booked 22 days in advance, depart on a Monday or Wednesday and return on a Monday

Find flight deals from Chicago to Santiago

Cheapest flights from Chicago to Santiago
Explore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/410:20 pmORD - SCL
1 stop14h 00mAvianca
Mon 11/101:35 amSCL - ORD
1 stop21h 45mAvianca
Deal found 10/22$557
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:16 pmMDW - SCL
2 stops28h 59mMultiple Airlines
Thu 12/1110:35 amSCL - MDW
1 stop14h 18mMultiple Airlines
Deal found 10/21$564
This FlightHub deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/191:25 pmORD - SCL
1 stop14h 30mLATAM Airlines
Wed 11/2611:30 pmSCL - ORD
1 stop21h 16mLATAM Airlines
Deal found 10/20$575
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/225:57 pmMDW - SCL
2 stops32h 53mMultiple Airlines
Sat 12/610:35 amSCL - MDW
1 stop14h 55mMultiple Airlines
Deal found 10/21$579
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/274:03 pmORD - SCL
3 stops28h 12mMultiple Airlines
Mon 11/37:25 amSCL - ORD
3 stops35h 50mMultiple Airlines
Deal found 10/20$580
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/510:20 pmORD - SCL
1 stop14h 00mMultiple Airlines
Thu 11/137:25 amSCL - ORD
3 stops34h 06mMultiple Airlines
Deal found 10/20$585
This FlightHub deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/101:25 pmORD - SCL
1 stop14h 30mLATAM Airlines
Sat 11/2211:30 pmSCL - ORD
1 stop16h 09mLATAM Airlines
Deal found 10/20$588
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1012:17 pmORD - SCL
2 stops30h 58mMultiple Airlines
Fri 11/2111:25 pmSCL - ORD
1 stop14h 10mMultiple Airlines
Deal found 10/20$592
This FlightHub deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/81:08 pmORD - SCL
1 stop14h 47mLATAM Airlines
Sat 11/2211:30 pmSCL - ORD
1 stop21h 23mLATAM Airlines
Deal found 10/21$597
This Cheapflightsfares deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/510:20 pmORD - SCL
1 stop14h 00mAvianca
Tue 11/111:35 amSCL - ORD
1 stop21h 45mAvianca
Deal found 10/22$598
This LATAM Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:45 amORD - SCL
2 stops20h 50mLATAM Airlines
Sat 11/2211:30 pmSCL - ORD
1 stop16h 09mLATAM Airlines
Deal found 10/21$600
This FlightHub deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1710:47 amMDW - SCL
2 stops16h 48mLATAM Airlines
Mon 11/2411:25 pmSCL - MDW
2 stops15h 27mLATAM Airlines
Deal found 10/19$618

Cheap flight deals from Chicago to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$557
(Cheapflightsfares)

One-way from

$263
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$803
Provider with most accurate pricing for Chicago (CHI)-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Santiago Arturo Merino Benitez flights.
Search Deals
From Chicago (CHI) to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Chicago (CHI) to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($132 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chicago to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
Use the filters below to find and compare flights from Chicago to Santiago that are best for you.

Fly from

Chicago

Fly to

Santiago

Route

Depart

Return

Price

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 11/13

6:56 am-12:06 am

1 stop14h 10m

Santiago Arturo Merino Benitez

Sat 11/15

3:23 am-12:05 am

1 stop23h 42m

$614

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Wed 11/12

6:56 am-3:43 am

1 stop17h 47m

Santiago Arturo Merino Benitez

Sat 11/15

3:23 am-12:05 am

1 stop23h 42m

$614

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 11/6

6:56 am-12:06 am

1 stop14h 10m

Santiago Arturo Merino Benitez

Wed 11/12

1:12 am-12:46 pm

1 stop14h 34m

$614

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Mon 11/17

12:47 pm-7:40 am

1 stop15h 53m

Santiago Arturo Merino Benitez

Mon 11/24

11:25 pm-11:52 am

2 stops15h 27m

$618

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Thu 11/6

10:40 am-7:40 am

1 stop18h 00m

Santiago Arturo Merino Benitez

Mon 11/10

6:30 pm-9:52 am

2 stops18h 22m

$626

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Wed 11/5

10:40 am-7:40 am

1 stop18h 00m

Santiago Arturo Merino Benitez

Wed 11/12

11:10 pm-4:38 pm

1 stop20h 28m

$626

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Thu 11/13

10:47 am-7:40 am

1 stop17h 53m

Santiago Arturo Merino Benitez

Thu 11/20

11:10 pm-9:52 am

1 stop13h 42m

$626

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 11/13

11:19 am-7:40 am

1 stop17h 21m

Santiago Arturo Merino Benitez

Thu 11/20

6:35 pm-10:19 am

2 stops18h 44m

$626

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 11/6

10:20 pm-12:30 am

1 stop23h 10m

Santiago Arturo Merino Benitez

Thu 11/13

7:25 am-2:31 pm

3 stops34h 06m

$630

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 11/10

10:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

Thu 11/20

1:35 am-10:35 am

3 stops36h 00m

$630

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/20

Showing 1-10 of 34 results
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Compare providers for flights from Chicago to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Santiago in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Chicago to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Santiago

How far ahead should I book a flight from Chicago to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Chicago to Santiago. Price data was last updated on October 17, 2025.

The price you pay for your flight from Chicago to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 22 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Chicago to Santiago?

Currently, February is the cheapest month in which you can book a flight from Chicago to Santiago (average of $452). Flying from Chicago to Santiago in August is currently the most expensive (average of $889). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to SCL?

Find hourly flight availability from Chicago to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 22, 2025.

When flying from Chicago to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 25% versus a flight in the afternoon.

How much does it cost to fly round-trip from Chicago to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated October 22, 2025.
Read through reviews of airlines operating flights from Chicago to Santiago, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,979 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,979 reviews
Delta
7.9
Good
7,979 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
LATAM Airlines
7.5
Good
1,869 reviews
Delta
7.9
Good
7,979 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,988 reviews
Delta
7.9
Good
7,979 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,028 reviews
Delta
7.9
Good
7,979 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Avianca
6.7
Okay
2,456 reviews
Delta
7.9
Good
7,979 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Chicago to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Chicago?

    For a flight from Chicago to Santiago, you will be flying into Arturo Merino Benitez. Santiago Arturo Merino Benitez (SCL) is just 8.4 mi from the center of the city. Arturo Merino Benitez is the only Santiago airport and it handles 0 inbound flights from Chicago per day. 7 airlines have flights to Santiago Arturo Merino Benitez from Chicago on a regular basis.

  • How long is the flight from Chicago to Santiago?

    Copa Airlines, LATAM Airlines, and Delta can get you from Chicago to Santiago in just under 14h 10m. Your travel time can differ by up to 3h 50m. Airlines will cover a distance of 5316 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Chicago to Santiago round-trip?

    According to our current data, Avianca ($564), Copa Airlines ($641), and Delta ($699) offers the cheapest pricing from Chicago to Santiago. Avianca is 33% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Chicago to Santiago that include hotel bookings?

    Yes. In addition to deals on Chicago to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Santiago.

  • Can I find deals for business class flights from Chicago to Santiago?

    Yes. Cheapflights offers flight deals from Chicago to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to Santiago?

    Currently, February is the cheapest month in which you can book a flight from Chicago to Santiago (average of $452). Flying from Chicago to Santiago in August is currently the most expensive (average of $889). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 7 airlines flying from Chicago to Santiago

Discover the top 7 airlines that operate flights from Chicago to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$564Average$738FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$641Average$843FlexibilityNo cancel feeOn-time70%
DeltaCheapest$699Average$920FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$703Average$1,034FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$703Average$1,013FlexibilityNo cancel feeOn-time71%
Air CanadaCheapest$707Average$951FlexibilityNo cancel feeOn-time67%
United AirlinesCheapest$748Average$923FlexibilityNo cancel feeOn-time69%

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