$290+ Cheap flights from Chicago (CHI) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/11. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — SCL
Jul 24 — Jul 311
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Santiago with Cheapflights
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Cheapest flights from Chicago to SantiagoExplore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 24, 2026.
Explore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/304:49 pm
ORD
- SCL
2 stops33h 07m
Multiple Airlines
Fri 10/237:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$644
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:13 pm
ORD
- SCL
2 stops32h 47m
Multiple Airlines
Tue 8/186:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$646
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:13 pm
ORD
- SCL
2 stops32h 47m
Multiple Airlines
Mon 8/176:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$652
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:44 pm
ORD
- SCL
2 stops30h 16m
Multiple Airlines
Fri 8/282:56 am
SCL
- ORD
1 stop23h 06m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$656
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:26 am
ORD
- SCL
2 stops16h 30m
Multiple Airlines
Mon 9/2812:22 pm
SCL
- ORD
1 stop14h 40m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$659
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:26 am
ORD
- SCL
2 stops18h 44m
Multiple Airlines
Fri 10/237:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$660
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:49 pm
ORD
- SCL
2 stops25h 43m
Multiple Airlines
Fri 10/237:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$669
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:13 pm
ORD
- SCL
2 stops31h 37m
Multiple Airlines
Tue 8/186:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$680
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:13 pm
ORD
- SCL
2 stops32h 47m
Multiple Airlines
Sun 8/236:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$688
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:13 pm
ORD
- SCL
2 stops31h 37m
Multiple Airlines
Sat 8/86:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$689
This Avianca deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1211:20 pm
ORD
- SCL
1 stop13h 55m
Avianca
Mon 7/2712:30 am
SCL
- ORD
1 stop21h 50m
Avianca
Deal found 6/23![Avianca logo]()
$690
This Avianca deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:20 pm
ORD
- SCL
1 stop14h 00m
Avianca
Sun 11/151:35 am
SCL
- ORD
1 stop21h 45m
Avianca
Deal found 6/23![Avianca logo]()
$691
Best flights from Chicago to SantiagoDiscover carefully curated flight deals from Chicago to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 24, 2026.
Discover carefully curated flight deals from Chicago to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 24, 2026.
This Avianca deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1211:20 pm
ORD
- SCL
1 stop13h 55m
Avianca
Mon 7/2712:30 am
SCL
- ORD
1 stop21h 50m
Avianca
Deal found 6/23![Avianca logo]()
$690
This Copa Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:21 pm
ORD
- SCL
1 stop30h 22m
Copa Airlines
Wed 8/262:56 am
SCL
- ORD
1 stop23h 06m
Copa Airlines
Deal found 6/20![Copa Airlines logo]()
$692
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:00 pm
ORD
- SCL
1 stop16h 25m
Delta
Tue 8/1810:55 pm
SCL
- ORD
1 stop23h 57m
Delta
Deal found 6/23![Delta logo]()
$705
This LATAM Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:54 am
MDW
- SCL
2 stops27h 06m
LATAM Airlines
Mon 8/3111:00 pm
SCL
- MDW
2 stops24h 36m
LATAM Airlines
Deal found 6/23![LATAM Airlines logo]()
$710
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:52 am
ORD
- SCL
2 stops21h 23m
Delta
Tue 7/218:40 pm
SCL
- ORD
2 stops17h 23m
Delta
Deal found 6/24![Delta logo]()
$710
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:30 am
ORD
- SCL
1 stop24h 45m
Delta
Tue 8/188:40 pm
SCL
- ORD
1 stop13h 43m
Delta
Deal found 6/23![Delta logo]()
$713
This Expedia deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/224:39 pm
MDW
- SCL
1 stop13h 36m
LATAM Airlines
Sat 8/298:30 am
SCL
- MDW
3 stops26h 29m
LATAM Airlines
Deal found 6/22![LATAM Airlines logo]()
$796
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:05 am
ORD
- SCL
1 stop22h 10m
Delta
Mon 8/1710:55 pm
SCL
- ORD
1 stop19h 11m
Delta
Deal found 6/23![Delta logo]()
$735
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/224:39 pm
MDW
- SCL
1 stop13h 36m
Delta
Sat 8/2911:00 pm
SCL
- MDW
2 stops20h 33m
Delta
Deal found 6/23![Delta logo]()
$740
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2210:56 am
MDW
- SCL
2 stops18h 04m
Delta
Thu 8/278:40 pm
SCL
- MDW
2 stops16h 59m
Delta
Deal found 6/20![Delta logo]()
$770
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2610:54 am
MDW
- SCL
1 stop19h 21m
Delta
Mon 8/3111:00 pm
SCL
- MDW
2 stops17h 44m
Delta
Deal found 6/21![Delta logo]()
$770
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:30 am
ORD
- SCL
2 stops23h 30m
Delta
Sat 8/1511:00 pm
SCL
- ORD
2 stops22h 30m
Delta
Deal found 6/19![Delta logo]()
$770
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/191:50 pm
ORD
- SCL
1 stop16h 25m
Delta
Mon 8/3111:00 pm
SCL
- ORD
2 stops18h 51m
Delta
Deal found 6/22![Delta logo]()
$770
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:50 pm
ORD
- SCL
2 stops16h 05m
Delta
Mon 8/3111:00 pm
SCL
- ORD
2 stops20h 49m
Delta
Deal found 6/21![Delta logo]()
$770
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:30 am
ORD
- SCL
1 stop24h 45m
Delta
Sun 8/1610:55 pm
SCL
- ORD
1 stop23h 57m
Delta
Deal found 6/19![Delta logo]()
$771
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:54 am
MDW
- SCL
2 stops18h 06m
Delta
Sun 8/911:00 pm
SCL
- MDW
2 stops20h 33m
Delta
Deal found 6/23![Delta logo]()
$919
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/44:25 pm
MDW
- SCL
1 stop13h 50m
Delta
Wed 7/88:40 pm
SCL
- MDW
1 stop14h 25m
Delta
Deal found 6/21![Delta logo]()
$960
Last-minute flights from Chicago to SantiagoDiscover last-minute flight deals from Chicago to Santiago. Data last updated June 24, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Santiago. Data last updated June 24, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:08 am
ORD
- SCL
1 stop22h 07m
Multiple Airlines
Sun 8/26:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$817
This FlightHub deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/21:46 pm
ORD
- SCL
2 stops16h 09m
LATAM Airlines
Sun 7/510:55 pm
SCL
- ORD
1 stop19h 16m
LATAM Airlines
Deal found 6/23![LATAM Airlines logo]()
$796
This oojo deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/411:20 pm
ORD
- SCL
1 stop28h 25m
Avianca
Wed 7/86:40 am
SCL
- ORD
1 stop15h 40m
Avianca
Deal found 6/21![Avianca logo]()
$823
This Avianca deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1211:20 pm
ORD
- SCL
1 stop13h 55m
Avianca
Mon 7/2712:30 am
SCL
- ORD
1 stop21h 50m
Avianca
Deal found 6/23![Avianca logo]()
$690
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/132:29 pm
ORD
- SCL
1 stop15h 31m
American Airlines
Thu 7/239:00 pm
SCL
- ORD
1 stop23h 53m
American Airlines
Deal found 6/19![American Airlines logo]()
$766
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:03 am
ORD
- SCL
1 stop22h 12m
Delta
Tue 7/218:40 pm
SCL
- ORD
1 stop16h 54m
Delta
Deal found 6/24![Delta logo]()
$705
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:03 am
ORD
- SCL
1 stop22h 12m
Multiple Airlines
Sun 7/266:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$822
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:21 pm
ORD
- SCL
1 stop12h 53m
Multiple Airlines
Sun 7/266:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$811
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:13 pm
ORD
- SCL
2 stops32h 47m
Multiple Airlines
Wed 7/296:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$808
This LATAM Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2211:05 am
MDW
- SCL
2 stops26h 45m
LATAM Airlines
Thu 7/308:40 pm
SCL
- MDW
1 stop16h 16m
LATAM Airlines
Deal found 6/19![LATAM Airlines logo]()
$831
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:02 am
ORD
- SCL
1 stop13h 41m
Multiple Airlines
Sun 8/26:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$789
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:02 am
ORD
- SCL
1 stop13h 41m
Multiple Airlines
Thu 8/136:40 am
SCL
- ORD
1 stop15h 40m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$813
One-way flights from Chicago to SantiagoSearch for one-way flight options from Chicago to Santiago. Find affordable one-way fares based on user searches. Data last updated June 24, 2026.
Search for one-way flight options from Chicago to Santiago. Find affordable one-way fares based on user searches. Data last updated June 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:13 pm
ORD
- SCL
2 stops32h 47m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:13 pm
ORD
- SCL
2 stops49h 23m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:13 pm
ORD
- SCL
2 stops32h 47m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:13 pm
ORD
- SCL
2 stops49h 23m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:13 pm
ORD
- SCL
2 stops52h 30m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$350
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/41:50 pm
ORD
- SCL
3 stops35h 00m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/31:50 pm
ORD
- SCL
3 stops35h 00m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$378
This eDestinos deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:13 pm
ORD
- SCL
2 stops43h 22m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$393
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:05 am
ORD
- SCL
3 stops35h 31m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$403
This FlightHub deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:46 pm
MDW
- SCL
2 stops17h 09m
LATAM Airlines
Deal found 6/23![LATAM Airlines logo]()
$431
This SmartFares deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:54 am
MDW
- SCL
1 stop19h 21m
LATAM Airlines
Deal found 6/22![LATAM Airlines logo]()
$458
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:00 am
MDW
- SCL
1 stop24h 15m
Delta
Deal found 6/21![Delta logo]()
$466
Find flight deals from Chicago to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $644 (Kiwi.com) |
One-way from | $290 (Kiwi.com) |
Popular in | September |
Cheapest in | March |
Average price | $805 |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 24, 2026.
Use the filters below to find and compare flights from Chicago to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sun 7/12
11:20 pm-2:15 pm
1 stop13h 55m
Santiago Arturo Merino Benitez
Mon 7/27
12:30 am-9:20 pm
1 stop21h 50m
$690
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sat 8/22
3:21 pm-10:43 pm
1 stop30h 22m
Santiago Arturo Merino Benitez
Wed 8/26
2:56 am-1:02 am
1 stop23h 06m
$692
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Thu 8/13
1:00 pm-6:25 am
1 stop16h 25m
Santiago Arturo Merino Benitez
Tue 8/18
10:55 pm-9:52 pm
1 stop23h 57m
$705
ChicagoSantiago
MDW - SCL
MDWSCL
Chicago Midway
Fri 8/28
10:54 am-3:00 pm
2 stops27h 06m
Santiago Arturo Merino Benitez
Mon 8/31
11:00 pm-10:36 pm
2 stops24h 36m
$710
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Tue 7/14
8:52 am-7:15 am
2 stops21h 23m
Santiago Arturo Merino Benitez
Tue 7/21
8:40 pm-1:03 pm
2 stops17h 23m
$710
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sun 8/16
5:30 am-7:15 am
1 stop24h 45m
Santiago Arturo Merino Benitez
Tue 8/18
8:40 pm-9:23 am
1 stop13h 43m
$713
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Tue 8/11
8:05 am-7:15 am
1 stop22h 10m
Santiago Arturo Merino Benitez
Mon 8/17
10:55 pm-5:06 pm
1 stop19h 11m
$735
ChicagoSantiago
MDW - SCL
MDWSCL
Chicago Midway
Sat 8/22
4:39 pm-7:15 am
1 stop13h 36m
Santiago Arturo Merino Benitez
Sat 8/29
11:00 pm-6:33 pm
2 stops20h 33m
$740
ChicagoSantiago
MDW - SCL
MDWSCL
Chicago Midway
Sat 8/22
10:56 am-6:00 am
2 stops18h 04m
Santiago Arturo Merino Benitez
Thu 8/27
8:40 pm-12:39 pm
2 stops16h 59m
$770
ChicagoSantiago
MDW - SCL
MDWSCL
Chicago Midway
Wed 8/26
10:54 am-7:15 am
1 stop19h 21m
Santiago Arturo Merino Benitez
Mon 8/31
11:00 pm-3:44 pm
2 stops17h 44m
$770
Showing 1-10 of 33 resultsSorted by cheapest first
Compare providers for flights from Chicago to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Santiago in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Chicago-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Chicago to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Chicago with our price prediction graph.
CHI-SCL
ORD-SCL
MDW-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Santiago
CHI-SCL
ORD-SCL
MDW-SCL
What is the cheapest month to book a flight from Chicago to Santiago?
Currently, March is the cheapest month in which you can book a flight from Chicago to Santiago (average of $302). Flying from Chicago to Santiago in November is currently the most expensive (average of $626). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Chicago to Santiago?
What’s the top layover airport for flights from Chicago to Santiago?
Share of 1-stop round-trip flights from Chicago to Santiago chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 83% of 1-stop itineraries from Chicago to Santiago on Cheapflights.
What’s the cheapest layover airport for flights from Chicago to Santiago?
Average round-trip fare for 1-stop flights from Chicago to Santiago, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Bogotá (BOG) is the most affordable 1-stop option, with an average round-trip price of $558.
What’s the fastest layover option from Chicago to Santiago?
Shortest average travel time for 1-stop one-way flights from Chicago to Santiago, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 12h 38m.
Which airport typically offers the quickest layover for flights from Chicago to Santiago?
Average layover duration for 1-stop one-way flights from Chicago to Santiago, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 24m.
How often are flights from Chicago to Santiago delayed?
About 0% of weekly flights between Chicago and Santiago have experienced delays in the past year, with the average delay time being 0 minutes.
What is the most punctual flight time for Chicago to Santiago flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Wednesday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
How far ahead should I book a flight from Chicago to Santiago?
The price you pay for your flight from Chicago to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 88 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated June 24, 2026.
Read through reviews of airlines operating flights from Chicago to Santiago, such as Copa Airlines,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Overall
7.6
Boarding
7.8
Food
6.9
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Entertainment
6.8
Overall
7.6
Boarding
7.8
Food
6.9
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Entertainment
6.8
Overall
7.6
Boarding
7.8
Food
6.9
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Entertainment
6.8
Overall
7.6
Boarding
7.8
Food
6.9
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Entertainment
6.8
Overall
7.6
Boarding
7.8
Food
6.9
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Entertainment
6.8
Overall
7.6
Boarding
7.8
Food
6.9
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Related info for your journey
Find useful and relevant information for your journey from Chicago to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
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Search flights from Chicago to Santiago by cabin class
Find flights from Chicago to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Santiago flights
Browse other Chicago and Santiago flight options. Last updated on June 24, 2026.
Other flights from Chicago
Browse through other flights departing from Chicago. Flights are based on user searches made on Cheapflights and were last updated on June 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 24, 2026.
Top 6 airlines flying from Chicago to Santiago
Discover the top 6 airlines that operate flights from Chicago to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$537 | Average$680 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$540 | Average$750 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$558 | Average$790 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$597 | Average$906 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$626 | Average$796 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$626 | Average$903 | FlexibilityNo cancel fee | On-timeN/A |