$281+ Cheap flights from Chicago (CHI) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — SCL
Jul 12 — Jul 191
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Chicago to SantiagoExplore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
Explore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:13 pm
ORD
- SCL
2 stops32h 07m
Multiple Airlines
Thu 8/2711:22 am
SCL
- ORD
1 stop14h 40m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$637
This Justfly.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:50 pm
ORD
- SCL
2 stops15h 05m
LATAM Airlines
Mon 10/511:00 pm
SCL
- ORD
2 stops17h 13m
LATAM Airlines
Deal found 6/7![LATAM Airlines logo]()
$650
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/144:05 pm
ORD
- SCL
1 stop13h 55m
American Airlines
Tue 7/289:00 pm
SCL
- ORD
1 stop18h 58m
American Airlines
Deal found 6/8![American Airlines logo]()
$660
This Copa Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:21 pm
ORD
- SCL
1 stop27h 15m
Copa Airlines
Sun 8/164:14 am
SCL
- ORD
1 stop21h 48m
Copa Airlines
Deal found 6/8![Copa Airlines logo]()
$661
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:13 pm
ORD
- SCL
2 stops32h 07m
Multiple Airlines
Wed 9/211:22 am
SCL
- ORD
1 stop14h 40m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$662
This Booking.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/33:21 pm
ORD
- SCL
1 stop30h 22m
Copa Airlines
Sun 8/164:14 am
SCL
- ORD
1 stop21h 48m
Copa Airlines
Deal found 6/9![Copa Airlines logo]()
$663
This LATAM Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:05 am
ORD
- SCL
1 stop22h 10m
LATAM Airlines
Wed 8/1910:55 pm
SCL
- ORD
1 stop19h 11m
LATAM Airlines
Deal found 6/8![LATAM Airlines logo]()
$673
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:10 pm
MDW
- SCL
1 stop13h 05m
Delta
Sun 8/1611:00 pm
SCL
- MDW
2 stops20h 33m
Delta
Deal found 6/9![Delta logo]()
$678
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/122:30 pm
ORD
- SCL
1 stop15h 35m
American Airlines
Tue 8/188:50 pm
SCL
- ORD
2 stops17h 04m
American Airlines
Deal found 6/8![American Airlines logo]()
$678
This LATAM Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1412:41 pm
MDW
- SCL
1 stop17h 34m
LATAM Airlines
Tue 7/288:40 pm
SCL
- MDW
1 stop14h 25m
LATAM Airlines
Deal found 6/8![LATAM Airlines logo]()
$682
This Copa Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:01 am
ORD
- SCL
1 stop17h 55m
Copa Airlines
Sun 10/43:15 am
SCL
- ORD
1 stop23h 42m
Copa Airlines
Deal found 6/7![Copa Airlines logo]()
$692
This LATAM Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:05 am
ORD
- SCL
1 stop22h 10m
LATAM Airlines
Mon 8/3111:05 pm
SCL
- ORD
2 stops25h 52m
LATAM Airlines
Deal found 6/8![LATAM Airlines logo]()
$695
Best flights from Chicago to SantiagoDiscover carefully curated flight deals from Chicago to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
Discover carefully curated flight deals from Chicago to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
This Copa Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:02 am
ORD
- SCL
1 stop13h 41m
Copa Airlines
Mon 8/1712:43 am
SCL
- ORD
1 stop25h 19m
Copa Airlines
Deal found 6/8![Copa Airlines logo]()
$661
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:10 pm
MDW
- SCL
1 stop13h 05m
Delta
Tue 7/2811:00 pm
SCL
- MDW
2 stops20h 25m
Delta
Deal found 6/8![Delta logo]()
$700
This LATAM Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:30 am
ORD
- SCL
2 stops31h 05m
Multiple Airlines
Tue 8/258:30 am
SCL
- ORD
1 stop16h 23m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$756
This LATAM Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1612:46 pm
MDW
- SCL
2 stops15h 49m
LATAM Airlines
Wed 8/198:30 am
SCL
- MDW
3 stops26h 29m
LATAM Airlines
Deal found 6/9![LATAM Airlines logo]()
$764
This Copa Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:21 pm
ORD
- SCL
1 stop30h 22m
Copa Airlines
Wed 8/2611:22 am
SCL
- ORD
1 stop14h 40m
Copa Airlines
Deal found 6/9![Copa Airlines logo]()
$747
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:54 am
MDW
- SCL
2 stops18h 06m
Delta
Thu 8/276:45 pm
SCL
- MDW
2 stops22h 30m
Delta
Deal found 6/12![Delta logo]()
$759
This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/33:21 pm
ORD
- SCL
1 stop27h 15m
Copa Airlines
Sun 8/164:14 am
SCL
- ORD
1 stop21h 48m
Copa Airlines
Deal found 6/10![Copa Airlines logo]()
$747
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:03 am
ORD
- SCL
1 stop22h 12m
Delta
Sun 7/1210:55 pm
SCL
- ORD
1 stop23h 57m
Delta
Deal found 6/10![Delta logo]()
$759
This Copa Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:02 am
ORD
- SCL
1 stop17h 58m
Copa Airlines
Mon 8/2411:22 am
SCL
- ORD
1 stop14h 40m
Copa Airlines
Deal found 6/11![Copa Airlines logo]()
$747
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/79:45 am
ORD
- SCL
1 stop20h 30m
Delta
Tue 7/2110:55 pm
SCL
- ORD
1 stop19h 11m
Delta
Deal found 6/9![Delta logo]()
$759
This Copa Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/81:20 am
ORD
- SCL
1 stop20h 23m
Copa Airlines
Sat 8/152:14 am
SCL
- ORD
1 stop23h 48m
Copa Airlines
Deal found 6/9![Copa Airlines logo]()
$747
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/81:00 pm
MDW
- SCL
2 stops17h 15m
Delta
Tue 9/158:40 pm
SCL
- MDW
1 stop15h 13m
Delta
Deal found 6/9![Delta logo]()
$764
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1610:54 am
MDW
- SCL
2 stops19h 01m
Delta
Wed 8/1911:00 pm
SCL
- MDW
2 stops20h 33m
Delta
Deal found 6/9![Delta logo]()
$764
This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/193:21 pm
ORD
- SCL
1 stop30h 22m
Copa Airlines
Mon 8/314:14 am
SCL
- ORD
1 stop21h 48m
Copa Airlines
Deal found 6/10![Copa Airlines logo]()
$783
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/101:27 pm
MDW
- SCL
2 stops16h 48m
Delta
Sun 8/3011:00 pm
SCL
- MDW
2 stops17h 44m
Delta
Deal found 6/12![Delta logo]()
$764
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:30 am
ORD
- SCL
2 stops17h 25m
Delta
Wed 10/218:40 pm
SCL
- ORD
1 stop13h 54m
Delta
Deal found 6/8![Delta logo]()
$764
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/101:59 pm
ORD
- SCL
2 stops16h 16m
Delta
Tue 9/111:00 pm
SCL
- ORD
2 stops18h 51m
Delta
Deal found 6/12![Delta logo]()
$786
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:35 am
MDW
- SCL
2 stops16h 00m
Delta
Mon 11/1611:10 pm
SCL
- MDW
1 stop20h 15m
Delta
Deal found 6/9![Delta logo]()
$800
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:46 pm
MDW
- SCL
1 stop17h 29m
Delta
Tue 9/111:00 pm
SCL
- MDW
2 stops17h 44m
Delta
Deal found 6/12![Delta logo]()
$822
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:00 pm
MDW
- SCL
2 stops15h 55m
Delta
Sun 10/2511:10 pm
SCL
- MDW
2 stops15h 23m
Delta
Deal found 6/10![Delta logo]()
$836
Last-minute flights from Chicago to SantiagoDiscover last-minute flight deals from Chicago to Santiago. Data last updated June 12, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Santiago. Data last updated June 12, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:10 pm
MDW
- SCL
1 stop13h 05m
Delta
Mon 7/138:40 pm
SCL
- MDW
1 stop20h 35m
Delta
Deal found 6/8![Delta logo]()
$763
This LATAM Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:22 pm
ORD
- SCL
1 stop14h 53m
LATAM Airlines
Mon 7/1310:55 pm
SCL
- ORD
1 stop19h 11m
LATAM Airlines
Deal found 6/8![LATAM Airlines logo]()
$763
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:05 am
MDW
- SCL
1 stop19h 10m
Delta
Tue 7/2110:55 pm
SCL
- MDW
2 stops20h 30m
Delta
Deal found 6/9![Delta logo]()
$764
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/79:45 am
ORD
- SCL
1 stop20h 30m
Delta
Tue 7/2111:00 pm
SCL
- ORD
2 stops20h 45m
Delta
Deal found 6/9![Delta logo]()
$764
This LATAM Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:10 pm
MDW
- SCL
1 stop13h 05m
LATAM Airlines
Mon 7/133:20 pm
SCL
- MDW
2 stops19h 45m
LATAM Airlines
Deal found 6/8![LATAM Airlines logo]()
$765
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:10 pm
MDW
- SCL
1 stop13h 05m
Delta
Tue 7/1411:00 pm
SCL
- MDW
2 stops20h 25m
Delta
Deal found 6/7![Delta logo]()
$768
This LATAM Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/131:44 pm
ORD
- SCL
1 stop16h 31m
LATAM Airlines
Mon 7/2710:55 pm
SCL
- ORD
1 stop19h 11m
LATAM Airlines
Deal found 6/9![LATAM Airlines logo]()
$759
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/144:05 pm
ORD
- SCL
1 stop13h 55m
American Airlines
Tue 7/289:00 pm
SCL
- ORD
1 stop18h 58m
American Airlines
Deal found 6/8![American Airlines logo]()
$660
This LATAM Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1412:41 pm
MDW
- SCL
1 stop17h 34m
LATAM Airlines
Tue 7/288:40 pm
SCL
- MDW
1 stop14h 25m
LATAM Airlines
Deal found 6/8![LATAM Airlines logo]()
$682
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/141:18 pm
MDW
- SCL
2 stops16h 07m
Delta
Tue 7/2811:00 pm
SCL
- MDW
2 stops20h 25m
Delta
Deal found 6/8![Delta logo]()
$700
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:35 am
ORD
- SCL
1 stop23h 40m
Delta
Fri 7/248:40 pm
SCL
- ORD
1 stop21h 32m
Delta
Deal found 6/8![Delta logo]()
$701
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:13 pm
ORD
- SCL
2 stops56h 47m
Multiple Airlines
Mon 7/2712:43 am
SCL
- ORD
1 stop14h 14m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$744
One-way flights from Chicago to SantiagoSearch for one-way flight options from Chicago to Santiago. Find affordable one-way fares based on user searches. Data last updated June 12, 2026.
Search for one-way flight options from Chicago to Santiago. Find affordable one-way fares based on user searches. Data last updated June 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:44 pm
ORD
- SCL
2 stops31h 04m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:30 pm
ORD
- SCL
2 stops34h 40m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:30 pm
ORD
- SCL
2 stops44h 30m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:13 pm
ORD
- SCL
2 stops49h 23m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:11 pm
MDW
- SCL
3 stops40h 03m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/41:50 pm
ORD
- SCL
3 stops38h 24m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:05 am
MDW
- SCL
3 stops43h 15m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$350
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/51:50 pm
ORD
- SCL
3 stops35h 30m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$350
This Booking.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:15 am
ORD
- SCL
1 stop19h 35m
Air Canada
Deal found 6/12![Air Canada logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:03 pm
ORD
- SCL
3 stops34h 35m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/31:50 pm
ORD
- SCL
3 stops35h 00m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/811:06 am
MDW
- SCL
3 stops38h 54m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$368
Find flight deals from Chicago to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $637 (Kiwi.com) |
One-way from | $281 (Kiwi.com) |
Popular in | December |
Cheapest in | March |
Average price | $805 |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from Chicago to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Wed 8/12
8:02 am-10:43 pm
1 stop13h 41m
Santiago Arturo Merino Benitez
Mon 8/17
12:43 am-1:02 am
1 stop25h 19m
$661
ChicagoSantiago
MDW - SCL
MDWSCL
Chicago Midway
Tue 7/14
5:10 pm-7:15 am
1 stop13h 05m
Santiago Arturo Merino Benitez
Tue 7/28
11:00 pm-6:25 pm
2 stops20h 25m
$700
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Thu 8/6
3:21 pm-10:43 pm
1 stop30h 22m
Santiago Arturo Merino Benitez
Wed 8/26
11:22 am-1:02 am
1 stop14h 40m
$747
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Mon 8/3
3:21 pm-7:36 pm
1 stop27h 15m
Santiago Arturo Merino Benitez
Sun 8/16
4:14 am-1:02 am
1 stop21h 48m
$747
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sun 8/16
8:02 am-3:00 am
1 stop17h 58m
Santiago Arturo Merino Benitez
Mon 8/24
11:22 am-1:02 am
1 stop14h 40m
$747
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sat 8/8
1:20 am-10:43 pm
1 stop20h 23m
Santiago Arturo Merino Benitez
Sat 8/15
2:14 am-1:02 am
1 stop23h 48m
$747
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Thu 8/6
5:30 am-1:35 pm
2 stops31h 05m
Santiago Arturo Merino Benitez
Tue 8/25
8:30 am-11:53 pm
1 stop16h 23m
$756
ChicagoSantiago
MDW - SCL
MDWSCL
Chicago Midway
Tue 8/11
10:54 am-6:00 am
2 stops18h 06m
Santiago Arturo Merino Benitez
Thu 8/27
6:45 pm-4:15 pm
2 stops22h 30m
$759
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Wed 7/8
8:03 am-7:15 am
1 stop22h 12m
Santiago Arturo Merino Benitez
Sun 7/12
10:55 pm-9:52 pm
1 stop23h 57m
$759
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Tue 7/7
9:45 am-7:15 am
1 stop20h 30m
Santiago Arturo Merino Benitez
Tue 7/21
10:55 pm-5:06 pm
1 stop19h 11m
$759
Showing 1-10 of 38 resultsSorted by cheapest first
Compare providers for flights from Chicago to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Santiago in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Chicago-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Chicago to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Chicago with our price prediction graph.
CHI-SCL
ORD-SCL
MDW-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Santiago
CHI-SCL
ORD-SCL
MDW-SCL
What is the cheapest month to book a flight from Chicago to Santiago?
Currently, March is the cheapest month in which you can book a flight from Chicago to Santiago (average of $302). Flying from Chicago to Santiago in November is currently the most expensive (average of $626). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Chicago to Santiago?
What’s the top layover airport for flights from Chicago to Santiago?
Share of 1-stop round-trip flights from Chicago to Santiago chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 71% of 1-stop itineraries from Chicago to Santiago on Cheapflights.
What’s the cheapest layover airport for flights from Chicago to Santiago?
Average round-trip fare for 1-stop flights from Chicago to Santiago, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Bogotá (BOG) is the most affordable 1-stop option, with an average round-trip price of $558.
What’s the fastest layover option from Chicago to Santiago?
Shortest average travel time for 1-stop one-way flights from Chicago to Santiago, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 12h 38m.
Which airport typically offers the quickest layover for flights from Chicago to Santiago?
Average layover duration for 1-stop one-way flights from Chicago to Santiago, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 24m.
How often are flights from Chicago to Santiago delayed?
About 0% of weekly flights between Chicago and Santiago have experienced delays in the past year, with the average delay time being 0 minutes.
What is the most punctual flight time for Chicago to Santiago flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Wednesday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
How far ahead should I book a flight from Chicago to Santiago?
The price you pay for your flight from Chicago to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 88 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated June 12, 2026.
Read through reviews of airlines operating flights from Chicago to Santiago, such as Copa Airlines,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.9
Overall
7.5
Entertainment
6.8
Boarding
7.7
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Food
6.9
Overall
7.5
Entertainment
6.8
Boarding
7.7
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Food
6.9
Overall
7.5
Entertainment
6.8
Boarding
7.7
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Food
6.9
Overall
7.5
Entertainment
6.8
Boarding
7.7
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Food
6.9
Overall
7.5
Entertainment
6.8
Boarding
7.7
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Food
6.9
Overall
7.5
Entertainment
6.8
Boarding
7.7
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Related info for your journey
Find useful and relevant information for your journey from Chicago to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Chicago to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to Santiago by cabin class
Find flights from Chicago to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Santiago flights
Browse other Chicago and Santiago flight options. Last updated on June 12, 2026.
Other flights from Chicago
Browse through other flights departing from Chicago. Flights are based on user searches made on Cheapflights and were last updated on June 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 12, 2026.
Top 6 airlines flying from Chicago to Santiago
Discover the top 6 airlines that operate flights from Chicago to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$537 | Average$680 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$540 | Average$750 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$558 | Average$790 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$583 | Average$873 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$597 | Average$912 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$626 | Average$796 | FlexibilityNo cancel fee | On-time69% |