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$289+ Cheap flights from Chicago (CHI) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — SCL
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Find cheap flights from Chicago to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from Chicago to Santiago Arturo Merino Benitez are usually found in September or August, booked 22 days in advance, depart on a Monday or Wednesday and return on a Monday

Cheap flight deals from Chicago to Santiago

Cheapest flights from Chicago to Santiago
Explore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/510:20 pmORD - SCL
1 stop14h 00mMultiple Airlines
Fri 12/1212:20 pmSCL - ORD
1 stop14h 45mMultiple Airlines
Deal found 12/4$695
This Priceline deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/610:20 pmORD - SCL
1 stop14h 00mAvianca
Mon 12/81:35 amSCL - ORD
1 stop21h 45mAvianca
Deal found 12/2$701
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/77:20 amORD - SCL
2 stops19h 10mMultiple Airlines
Mon 12/81:35 amSCL - ORD
1 stop21h 45mMultiple Airlines
Deal found 12/2$708
This Priceline deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/410:20 pmORD - SCL
1 stop23h 10mAvianca
Wed 12/107:25 amSCL - ORD
1 stop15h 55mAvianca
Deal found 12/2$718
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/62:26 pmORD - SCL
2 stops36h 04mMultiple Airlines
Mon 12/81:35 amSCL - ORD
1 stop21h 45mMultiple Airlines
Deal found 12/2$731
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:41 pmORD - SCL
2 stops33h 34mMultiple Airlines
Wed 12/1011:25 pmSCL - ORD
1 stop22h 11mMultiple Airlines
Deal found 12/2$732
This KAYAK deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/64:29 pmMDW - SCL
2 stops21h 51mLATAM Airlines
Mon 12/84:35 amSCL - MDW
2 stops22h 12mLATAM Airlines
Deal found 12/2$739
This KAYAK deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:45 amORD - SCL
3 stops28h 45mLATAM Airlines
Wed 12/1012:20 pmSCL - ORD
2 stops23h 19mLATAM Airlines
Deal found 12/2$744
This Copa Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:33 amORD - SCL
1 stop17h 10mCopa Airlines
Tue 12/163:23 amSCL - ORD
1 stop23h 42mCopa Airlines
Deal found 12/2$752
This eDestinos deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:45 amORD - SCL
3 stops44h 05mMultiple Airlines
Fri 12/1911:25 pmSCL - ORD
2 stops49h 07mMultiple Airlines
Deal found 12/3$753
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:07 pmORD - SCL
2 stops29h 03mMultiple Airlines
Wed 12/1011:25 pmSCL - ORD
1 stop22h 11mMultiple Airlines
Deal found 12/2$755
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:21 pmORD - SCL
1 stop15h 29mUnited Airlines
Fri 12/1910:45 pmSCL - ORD
1 stop24h 10mUnited Airlines
Deal found 12/2$757

Find flight deals from Chicago to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$655
(American Airlines)

One-way from

$289
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$1,131
Provider with most accurate pricing for Chicago (CHI)-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Santiago Arturo Merino Benitez flights.
Search Deals
From Chicago (CHI) to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Chicago (CHI) to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($100 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chicago to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Chicago to Santiago that are best for you.

Fly from

Chicago

Fly to

Santiago

Route

Depart

Return

Price

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 1/12

3:55 pm-9:00 am

1 stop14h 05m

Santiago Arturo Merino Benitez

Mon 1/26

10:35 pm-11:35 am

2 stops16h 00m

$655

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sat 1/17

3:53 pm-8:50 am

1 stop13h 57m

Santiago Arturo Merino Benitez

Sat 1/24

10:45 pm-10:07 am

1 stop14h 22m

$658

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 1/22

4:50 pm-8:50 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Sat 2/14

10:45 pm-9:17 am

1 stop13h 32m

$676

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Mon 2/2

9:33 am-7:40 am

2 stops19h 07m

Santiago Arturo Merino Benitez

Tue 2/17

11:10 pm-5:37 pm

2 stops21h 27m

$699

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 2/2

10:35 am-7:40 am

2 stops18h 05m

Santiago Arturo Merino Benitez

Tue 2/17

11:10 pm-4:41 pm

2 stops20h 31m

$699

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 12/7

10:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

Mon 12/8

1:35 am-8:20 pm

1 stop21h 45m

$701

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 12/7

7:20 am-5:30 am

2 stops19h 10m

Santiago Arturo Merino Benitez

Mon 12/8

1:35 am-8:20 pm

1 stop21h 45m

$708

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Thu 1/22

10:48 am-7:40 am

1 stop17h 52m

Santiago Arturo Merino Benitez

Sat 2/14

11:10 pm-3:21 pm

1 stop19h 11m

$708

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Sat 1/17

11:21 am-7:40 am

1 stop17h 19m

Santiago Arturo Merino Benitez

Sat 1/24

6:30 pm-9:53 am

2 stops18h 23m

$708

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Fri 1/16

11:21 am-7:40 am

1 stop17h 19m

Santiago Arturo Merino Benitez

Fri 1/23

11:10 pm-9:53 am

1 stop13h 43m

$708

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/1

Showing 1-10 of 37 results
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Compare providers for flights from Chicago to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Santiago in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Chicago-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Chicago-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Chicago to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Santiago

How far ahead should I book a flight from Chicago to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Chicago to Santiago. Price data was last updated on November 28, 2025.

The price you pay for your flight from Chicago to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 22 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Chicago to Santiago?

Currently, February is the cheapest month in which you can book a flight from Chicago to Santiago (average of $452). Flying from Chicago to Santiago in August is currently the most expensive (average of $889). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to SCL?

Find hourly flight availability from Chicago to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

When flying from Chicago to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 25% versus a flight in the afternoon.

How much does it cost to fly round-trip from Chicago to Santiago?

What’s the top layover airport for flights from Chicago to Santiago?

Share of 1-stop round-trip flights from Chicago to Santiago chosen by Cheapflights users in the past 12 months, using the same layover each way.

Panama City (PTY) – chosen by Cheapflights users on 80% of 1-stop itineraries from Chicago to Santiago on Cheapflights.

What’s the cheapest layover airport for flights from Chicago to Santiago?

Average round-trip fare for 1-stop flights from Chicago to Santiago, chosen by Cheapflights users in the past 12 months, with the same layover each way.

Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $667.

What’s the fastest layover option from Chicago to Santiago?

Shortest average travel time for 1-stop one-way flights from Chicago to Santiago, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.

Flights via Bogotá (BOG) have the shortest average one-way travel time for 1-stop routes: 12h 40m.

Which airport typically offers the quickest layover for flights from Chicago to Santiago?

Average layover duration for 1-stop one-way flights from Chicago to Santiago, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.

Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 24m.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated December 4, 2025.
Read through reviews of airlines operating flights from Chicago to Santiago, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,890 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,066 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,046 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Avianca
6.6
Okay
2,479 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Chicago to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Chicago?

    For a flight from Chicago to Santiago, you will be flying into Arturo Merino Benitez. Santiago Arturo Merino Benitez (SCL) is just 8.4 mi from the center of the city. Arturo Merino Benitez is the only Santiago airport and it handles 0 inbound flights from Chicago per day. 7 airlines have flights to Santiago Arturo Merino Benitez from Chicago on a regular basis.

  • How long is the flight from Chicago to Santiago?

    American Airlines, United Airlines, and Delta can get you from Chicago to Santiago in just under 13h 57m. Your travel time can differ by up to 5h 10m. Airlines will cover a distance of 5316 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Chicago to Santiago round-trip?

    According to our current data, LATAM Airlines ($468), Air Canada ($484), and Avianca ($564) offers the cheapest pricing from Chicago to Santiago. LATAM Airlines is 45% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Chicago to Santiago one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $284. Air Canada flights start at $354 while deals on American Airlines start at $432 one-way.

  • Can I find deals for flights from Chicago to Santiago that include hotel bookings?

    Yes. In addition to deals on Chicago to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Santiago.

  • Can I find deals for business class flights from Chicago to Santiago?

    Yes. Cheapflights offers flight deals from Chicago to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to Santiago?

    Currently, February is the cheapest month in which you can book a flight from Chicago to Santiago (average of $452). Flying from Chicago to Santiago in August is currently the most expensive (average of $889). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 7 airlines flying from Chicago to Santiago

Discover the top 7 airlines that operate flights from Chicago to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air CanadaCheapest$484Average$951FlexibilityNo cancel feeOn-time67%
AviancaCheapest$564Average$738FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$626Average$869FlexibilityNo cancel feeOn-time69%
DeltaCheapest$626Average$890FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$639Average$1,028FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$641Average$851FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$684Average$911FlexibilityNo cancel feeOn-time81%

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