Santa Cruz de la Sierra

$287+ Cheap flights from Michigan to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/11. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — VVI
Mar 22 — Mar 291
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Cheap flight deals from Michigan to Santa Cruz de la Sierra

Cheapest flights from Michigan to Santa Cruz de la Sierra
Explore the most affordable flight options available from Michigan to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2026.

This Copa Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/38:06 am
ORD
-
VVI
1 stop13h 36m
Copa Airlines
Mon 4/1311:48 am
VVI
-
ORD
1 stop14h 25m
Copa Airlines
Deal found 2/18$610
This Justfly.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2911:20 pm
ORD
-
VVI
1 stop26h 10m
Avianca
Fri 6/53:35 am
VVI
-
ORD
1 stop18h 45m
Avianca
Deal found 2/19$619
This Justfly.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2711:20 pm
ORD
-
VVI
1 stop25h 30m
Avianca
Thu 4/23:35 am
VVI
-
ORD
1 stop18h 45m
Avianca
Deal found 2/20$622
This KAYAK deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/103:21 pm
ORD
-
VVI
1 stop11h 10m
Copa Airlines
Tue 6/161:12 am
VVI
-
ORD
1 stop27h 48m
Copa Airlines
Deal found 2/20$635
This Avianca deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:20 pm
ORD
-
VVI
1 stop26h 10m
Avianca
Mon 5/183:35 am
VVI
-
ORD
1 stop18h 45m
Avianca
Deal found 2/19$640
This Justfly.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1711:20 pm
ORD
-
VVI
1 stop26h 15m
Avianca
Mon 3/233:40 am
VVI
-
ORD
1 stop18h 40m
Avianca
Deal found 2/17$643
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/249:07 am
ORD
-
VVI
2 stops17h 24m
United Airlines
Sat 5/3011:47 am
VVI
-
ORD
2 stops25h 01m
United Airlines
Deal found 2/17$655
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:20 pm
ORD
-
VVI
2 stops50h 30m
United Airlines
Mon 3/211:54 am
VVI
-
ORD
2 stops23h 24m
United Airlines
Deal found 2/16$662
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/49:28 pm
ORD
-
VVI
2 stops24h 14m
United Airlines
Tue 4/711:48 am
VVI
-
ORD
2 stops37h 57m
United Airlines
Deal found 2/18$665
This Justfly.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1011:20 pm
ORD
-
VVI
1 stop26h 10m
Avianca
Tue 6/163:35 am
VVI
-
ORD
1 stop18h 45m
Avianca
Deal found 2/19$671
This Avianca deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:45 am
ORD
-
VVI
2 stops14h 45m
Avianca
Sat 10/103:35 am
VVI
-
ORD
1 stop18h 45m
Avianca
Deal found 2/19$672
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/259:18 pm
ORD
-
VVI
2 stops24h 24m
United Airlines
Sat 5/911:47 am
VVI
-
ORD
2 stops22h 50m
United Airlines
Deal found 2/19$675

Find flight deals from Michigan to Santa Cruz de la Sierra

Keep the following information in mind while searching for Michigan to Santa Cruz de la Sierra flight deals. Data was last updated February 20, 2026.

Most accurate provider

AranGrant
2 stars

Most trusted provider

AranGrant
2 stars

Round-trip from

$610
(Copa Airlines)
Provider with most accurate pricing for Detroit (DTT)-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Provider most trusted by Cheapflights users for Detroit (DTT)-Santa Cruz de la Sierra Viru Viru Intl flights.
From Michigan to Santa Cruz de la Sierra Viru Viru Intl

Cheapflights Fare Finder

 
Customize your flight search to find flights from Michigan to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
Use the filters below to find and compare flights from Michigan to Santa Cruz de la Sierra that are best for you.

Fly from

Michigan

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Mon 4/13

3:05 pm-3:40 am

1 stop11h 35m

Santa Cruz de la Sierra Viru Viru Intl

Thu 5/7

11:47 am-1:15 am

1 stop14h 28m

$610

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Fri 4/3

3:05 pm-3:40 am

1 stop11h 35m

Santa Cruz de la Sierra Viru Viru Intl

Sun 4/12

1:15 am-1:50 pm

1 stop13h 35m

$610

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sat 4/4

8:06 am-10:42 pm

1 stop13h 36m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/7

11:48 am-1:13 am

1 stop14h 25m

$610

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Mon 4/6

3:05 pm-3:40 am

1 stop11h 35m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/13

11:48 am-1:13 am

1 stop14h 25m

$610

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Thu 4/23

8:06 am-10:42 pm

1 stop13h 36m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/27

11:48 am-1:13 am

1 stop14h 25m

$610

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Fri 4/24

3:05 pm-3:40 am

1 stop11h 35m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/27

11:48 am-1:13 am

1 stop14h 25m

$610

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Fri 3/27

11:20 pm-1:50 am

1 stop25h 30m

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/2

3:35 am-9:20 pm

1 stop18h 45m

$622

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sat 5/16

11:20 pm-2:30 am

1 stop26h 10m

Santa Cruz de la Sierra Viru Viru Intl

Mon 5/18

3:35 am-9:20 pm

1 stop18h 45m

$640

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Wed 5/20

5:00 am-2:30 am

2 stops21h 30m

Santa Cruz de la Sierra Viru Viru Intl

Sun 5/31

3:35 am-11:37 pm

2 stops20h 02m

$768

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Tue 3/17

8:15 am-2:35 am

2 stops18h 20m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/24

3:40 am-10:32 pm

2 stops18h 52m

$781

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/17

Showing 1-10 of 17 results
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Best time to book a flight from Michigan to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Michigan with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Michigan to Santa Cruz de la Sierra
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Michigan to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Santa Cruz de la Sierra from Michigan?

    Santa Cruz de la Sierra Viru Viru Intl (VVI), located 11.5 mi from the city center, is the airport you fly into when you book flights from Michigan to Santa Cruz de la Sierra.

  • How long is the flight from Michigan to Santa Cruz de la Sierra?

    A quick flight from Michigan to Santa Cruz de la Sierra can take about 11h 35m. Copa Airlines provides one of the quickest options available for as low as $610. There are 4410 mi between Michigan and Santa Cruz de la Sierra. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Michigan to Santa Cruz de la Sierra?

  • Can I find deals for flights from Michigan to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Michigan to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Michigan to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Michigan to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Michigan to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Michigan to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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