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Santa Cruz de la Sierra

$261+ Cheap flights from Michigan to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — VVI
Okt 19 — Okt 261
So 10/19
So 10/26
1 adult, Economy
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Cheap flight deals from Michigan to Santa Cruz de la Sierra

Keep the following information in mind while searching for Michigan to Santa Cruz de la Sierra flight deals. Data was last updated September 19, 2025.

Round-trip from

$417
(Copa Airlines)

One-way from

$261
(Avianca Connect)
From Michigan to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from Michigan to Santa Cruz de la Sierra Viru Viru Intl
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Find flight deals from Michigan to Santa Cruz de la Sierra

Cheapest flights from Michigan to Santa Cruz de la Sierra
Explore the most affordable flight options available from Michigan to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2025.

This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 11/116:56 amORD - VVI
1 stop13h 50mCopa Airlines
Mo 11/241:09 amVVI - ORD
1 stop13h 37mCopa Airlines
Deal found 9/17$417
This Travelocity deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 11/410:20 pmORD - VVI
1 stop26h 15mAvianca
Fr 11/213:40 amVVI - ORD
1 stop18h 40mAvianca
Deal found 9/17$454
This Avianca deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 11/107:35 amORD - VVI
2 stops17h 00mAvianca
Fr 11/213:40 amVVI - ORD
1 stop18h 40mAvianca
Deal found 9/17$509
This Avianca deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 11/178:50 amORD - VVI
2 stops15h 45mAvianca
So 11/233:40 amVVI - ORD
1 stop18h 40mAvianca
Deal found 9/17$519
This Avianca Connect deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 10/15:05 amORD - VVI
2 stops19h 45mMultiple Airlines
So 10/52:50 amVVI - ORD
2 stops21h 55mMultiple Airlines
Deal found 9/17$569
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 9/193:07 pmORD - VVI
1 stop11h 29mCopa Airlines
Sa 10/1811:59 amVVI - ORD
1 stop13h 22mCopa Airlines
Deal found 9/17$587
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 11/112:00 pmORD - VVI
2 stops30h 46mUnited Airlines
Mo 11/241:09 amVVI - ORD
2 stops25h 06mUnited Airlines
Deal found 9/17$603
This Avianca deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 11/48:50 amORD - VVI
2 stops15h 45mMultiple Airlines
Fr 11/213:40 amVVI - ORD
1 stop18h 40mMultiple Airlines
Deal found 9/17$607
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 11/2610:35 amORD - VVI
2 stops34h 11mUnited Airlines
Mo 12/11:09 amVVI - ORD
2 stops41h 56mUnited Airlines
Deal found 9/18$613
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 9/195:57 pmORD - VVI
2 stops30h 53mAvianca
Fr 10/172:50 amVVI - ORD
1 stop11h 25mAvianca
Deal found 9/17$615
This Expedia deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 11/2610:20 pmORD - VVI
1 stop26h 15mAvianca
Mo 12/13:40 amVVI - ORD
1 stop18h 40mAvianca
Deal found 9/17$631
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 11/115:05 amORD - VVI
2 stops19h 30mMultiple Airlines
Mo 11/243:40 amVVI - ORD
3 stops32h 04mMultiple Airlines
Deal found 9/17$647

Cheapflights Fare Finder

 
Customize your flight search to find flights from Michigan to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 19, 2025.
Use the filters below to find and compare flights from Michigan to Santa Cruz de la Sierra that are best for you.

Fly from

Michigan

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Mo 11/17

6:56 am-3:36 am

1 stop18h 40m

Santa Cruz de la Sierra Viru Viru Intl

Mo 11/24

11:40 am-12:05 am

1 stop14h 25m

$417

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Fr 1/2

7:05 am-2:35 am

2 stops17h 30m

Santa Cruz de la Sierra Viru Viru Intl

Sa 1/24

3:40 am-8:20 pm

1 stop18h 40m

$509

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Mo 11/10

7:35 am-2:35 am

2 stops17h 00m

Santa Cruz de la Sierra Viru Viru Intl

Fr 11/21

3:40 am-8:20 pm

1 stop18h 40m

$509

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Di 11/11

2:00 pm-10:46 pm

2 stops30h 46m

Santa Cruz de la Sierra Viru Viru Intl

Mo 11/24

1:09 am-12:15 am

2 stops25h 06m

$603

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Mo 11/17

6:20 pm-10:46 pm

2 stops26h 26m

Santa Cruz de la Sierra Viru Viru Intl

So 11/23

1:09 am-11:44 am

2 stops36h 35m

$603

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Mi 11/26

9:06 pm-10:46 pm

2 stops47h 40m

Santa Cruz de la Sierra Viru Viru Intl

Mo 12/1

1:09 am-11:51 am

2 stops36h 42m

$603

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Di 11/11

7:10 am-10:46 pm

2 stops37h 36m

Santa Cruz de la Sierra Viru Viru Intl

So 11/30

1:09 am-8:57 am

2 stops33h 48m

$603

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Mo 11/10

7:30 am-10:46 pm

2 stops37h 16m

Santa Cruz de la Sierra Viru Viru Intl

Fr 11/21

1:09 am-12:15 am

2 stops25h 06m

$603

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Mi 10/1

9:20 pm-10:40 pm

2 stops24h 20m

Santa Cruz de la Sierra Viru Viru Intl

So 10/5

1:09 am-11:15 pm

2 stops23h 06m

$603

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Di 11/4

9:14 am-10:46 pm

2 stops35h 32m

Santa Cruz de la Sierra Viru Viru Intl

Fr 11/21

1:09 am-9:46 am

2 stops34h 37m

$603

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 23 results
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Best time to book a flight from Michigan to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Michigan with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Michigan to Santa Cruz de la Sierra
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Michigan to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Michigan?

    Santa Cruz de la Sierra Viru Viru Intl (VVI), located 11.5 mi from the city center, is the airport you fly into when you book flights from Michigan to Santa Cruz de la Sierra.

  • How long is the flight from Michigan to Santa Cruz de la Sierra?

    A quick flight from Michigan to Santa Cruz de la Sierra can take about 17h 30m. Copa Airlines provides one of the quickest options available for as low as $509. There are 4410 mi between Michigan and Santa Cruz de la Sierra. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Michigan to Santa Cruz de la Sierra?

    The most popular route from Michigan to Santa Cruz de la Sierra is Chicago O'Hare Intl - Santa Cruz de la Sierra Viru Viru Intl. You may also consider South Bend/Michiana - Santa Cruz de la Sierra Viru Viru Intl or Detroit Metropolitan Wayne County - Santa Cruz de la Sierra Viru Viru Intl.

  • Can I find deals for flights from Michigan to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Michigan to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Michigan to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Michigan to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Michigan to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Michigan to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Michigan to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Michigan to Santa Cruz de la Sierra (average of $597). Flying from Michigan to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Michigan to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
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