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$354+ Cheap flights from Panama City (PTY) to Santa Ana, CA (SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SNA
Nov 22 — Nov 291
Sat 11/22
Sat 11/29
1 adult, Economy
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Find flight deals from Panama City to Santa Ana

Cheapest flights from Panama City to Santa Ana
Explore the most affordable flight options available from Panama City to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.

This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/711:35 amPTY - SNA
1 stop13h 14mUnited Airlines
Sun 12/147:50 pmSNA - PTY
1 stop19h 59mUnited Airlines
Deal found 10/23$695
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/213:35 pmPTY - SNA
1 stop29h 43mUnited Airlines
Mon 11/244:15 pmSNA - PTY
2 stops19h 30mUnited Airlines
Deal found 10/22$717
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/218:55 amPTY - SNA
2 stops14h 37mUnited Airlines
Mon 12/18:15 amSNA - PTY
1 stop8h 23mUnited Airlines
Deal found 10/21$1,078

Cheap flight deals from Panama City to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$695
(United Airlines)

One-way from

$354
(Kiwi.com)

Popular in

January

Cheapest in

May

Average price

$613
Provider with most accurate pricing for Panama City Tocumen Intl-Santa Ana J. Wayne/Orange Cnty flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Santa Ana J. Wayne/Orange Cnty flights.
Search Deals
From Panama City Tocumen Intl to Santa Ana J. Wayne/Orange Cnty
Search Deals
One-way flight from Panama City Tocumen Intl to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($46 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Panama City to Santa Ana that are best for you.

Fly from

Panama City

Fly to

Santa Ana

Route

Depart

Return

Price

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sun 12/7

11:35 am-9:49 pm

1 stop13h 14m

Santa Ana J. Wayne/Orange Cnty

Sun 12/14

7:50 pm-6:49 pm

1 stop19h 59m

$695

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Wed 11/5

8:55 am-10:19 pm

2 stops16h 24m

Santa Ana J. Wayne/Orange Cnty

Thu 1/1

8:20 am-7:38 pm

1 stop8h 18m

$695

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sat 12/6

4:41 pm-9:19 am

2 stops19h 38m

Santa Ana J. Wayne/Orange Cnty

Sat 12/13

6:25 pm-5:07 pm

2 stops19h 42m

$717

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Fri 11/21

3:35 pm-6:18 pm

1 stop29h 43m

Santa Ana J. Wayne/Orange Cnty

Mon 12/1

3:14 pm-2:45 pm

1 stop20h 31m

$717

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Fri 11/21

3:35 pm-11:12 am

1 stop22h 37m

Santa Ana J. Wayne/Orange Cnty

Mon 11/24

7:34 pm-6:49 pm

1 stop20h 15m

$717

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Mon 3/16

7:55 am-9:45 pm

1 stop15h 50m

$381

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Tue 3/24

11:35 am-9:45 pm

1 stop12h 10m

$381

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sun 11/9

11:25 am-9:01 pm

3 stops36h 36m

$391

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sun 3/15

3:41 pm-9:45 pm

1 stop32h 04m

$402

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sun 11/9

3:35 pm-1:54 pm

1 stop25h 19m

$424

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/21

Showing 1-10 of 12 results
1
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Compare providers for flights from Panama City to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Santa Ana in October.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Santa Ana, California flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Santa Ana, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Santa Ana

What is the cheapest month to book a flight from Panama City to Santa Ana, California?

Currently, May is the cheapest month in which you can book a flight from Panama City to Santa Ana, California (average of $223). Flying from Panama City to Santa Ana, California in February is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Santa Ana, California?

    Departing from Panama City to Santa Ana, California will take you 13h 14m. There are 2973 mi between Panama City and Santa Ana, California.

  • Can I find deals for flights from Panama City to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Panama City to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Santa Ana.

  • Can I find deals for business class flights from Panama City to Santa Ana?

    Yes. Cheapflights offers flight deals from Panama City to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Santa Ana, California?

    Currently, May is the cheapest month in which you can book a flight from Panama City to Santa Ana, California (average of $223). Flying from Panama City to Santa Ana, California in February is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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