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$381+ Cheap flights from Panama City (PTY) to Santa Ana, CA (SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/3. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SNA
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Panama City to Santa Ana

Best flights from Panama City to Santa Ana
Discover carefully curated flight deals from Panama City to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:55 amPTY - SNA
1 stop15h 50mUnited Airlines
Sun 2/226:40 pmSNA - PTY
2 stops19h 27mUnited Airlines
Deal found 12/9$666
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/268:55 amPTY - SNA
1 stop15h 47mUnited Airlines
Mon 2/23:34 pmSNA - PTY
1 stop20h 11mUnited Airlines
Deal found 12/11$674

Find flight deals from Panama City to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$666
(United Airlines)

One-way from

$381
(United Airlines)

Popular in

January

Cheapest in

May

Average price

$622
Provider with most accurate pricing for Panama City Tocumen Intl-Santa Ana J. Wayne/Orange Cnty flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Santa Ana J. Wayne/Orange Cnty flights.
Search Deals
From Panama City Tocumen Intl to Santa Ana J. Wayne/Orange Cnty
Search Deals
One-way flight from Panama City Tocumen Intl to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($41 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Panama City to Santa Ana that are best for you.

Fly from

Panama City

Fly to

Santa Ana

Route

Depart

Return

Price

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Wed 2/18

8:55 am-9:45 pm

1 stop15h 50m

Santa Ana J. Wayne/Orange Cnty

Sun 2/22

6:40 pm-5:07 pm

2 stops19h 27m

$666

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Mon 1/26

8:55 am-9:42 pm

1 stop15h 47m

Santa Ana J. Wayne/Orange Cnty

Mon 2/2

3:34 pm-2:45 pm

1 stop20h 11m

$674

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Tue 2/3

8:55 am-8:42 pm

2 stops14h 47m

$381

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sat 1/3

2:53 pm-11:56 am

2 stops24h 03m

$743

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sat 1/3

7:31 am-10:16 am

3 stops53h 45m

$794

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sat 1/3

4:41 pm-2:07 pm

1 stop24h 26m

$1,347

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Mon 3/9

7:50 pm-8:50 pm

2 stops27h 00m

$2,444

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sat 4/4

7:55 am-9:31 pm

1 stop15h 36m

$4,538

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Compare providers for flights from Panama City to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Santa Ana in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Santa Ana, California flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City-Santa Ana, California flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City-Santa Ana, California flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Santa Ana, California flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Santa Ana

What is the cheapest month to book a flight from Panama City to Santa Ana, California?

Currently, May is the cheapest month in which you can book a flight from Panama City to Santa Ana, California (average of $223). Flying from Panama City to Santa Ana, California in February is currently the most expensive (average of $399). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Santa Ana, California?

    Departing from Panama City to Santa Ana, California will take you 15h 50m. There are 2973 mi between Panama City and Santa Ana, California.

  • Can I find deals for flights from Panama City to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Panama City to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Santa Ana.

  • Can I find deals for business class flights from Panama City to Santa Ana?

    Yes. Cheapflights offers flight deals from Panama City to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Santa Ana, California?

    Currently, May is the cheapest month in which you can book a flight from Panama City to Santa Ana, California (average of $223). Flying from Panama City to Santa Ana, California in February is currently the most expensive (average of $399). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
Tustin

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