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$397+ Cheap flights from Panama City (PTY) to Santa Ana (SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/26. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SNA
Mar 12 — Mar 191
Thu 3/12
Thu 3/19
1 adult, Economy
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Cheap flight deals from Panama City to Santa Ana

Cheapest flights from Panama City to Santa Ana
Explore the most affordable flight options available from Panama City to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 10, 2026.

This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:55 am
PTY
-
SNA
2 stops16h 06m
United Airlines
Thu 7/307:54 am
SNA
-
PTY
1 stop8h 43m
United Airlines
Deal found 2/10$686
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:00 am
PTY
-
SNA
1 stop13h 53m
United Airlines
Sun 9/277:00 pm
SNA
-
PTY
2 stops21h 37m
United Airlines
Deal found 2/8$689
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/253:41 pm
PTY
-
SNA
2 stops23h 34m
United Airlines
Wed 4/18:00 am
SNA
-
PTY
1 stop8h 37m
United Airlines
Deal found 2/8$696
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/243:30 pm
PTY
-
SNA
1 stop21h 28m
United Airlines
Tue 8/47:54 am
SNA
-
PTY
1 stop8h 43m
United Airlines
Deal found 2/10$707
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/263:10 pm
PTY
-
SNA
2 stops20h 55m
American Airlines
Thu 4/27:18 pm
SNA
-
PTY
2 stops17h 43m
American Airlines
Deal found 2/9$710
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/253:41 pm
PTY
-
SNA
1 stop21h 46m
United Airlines
Fri 4/33:29 pm
SNA
-
PTY
1 stop20h 45m
United Airlines
Deal found 2/10$729
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/267:55 am
PTY
-
SNA
1 stop15h 41m
United Airlines
Sun 8/22:58 pm
SNA
-
PTY
1 stop23h 14m
United Airlines
Deal found 2/10$750
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/273:41 pm
PTY
-
SNA
2 stops20h 07m
United Airlines
Mon 4/66:28 pm
SNA
-
PTY
2 stops19h 44m
United Airlines
Deal found 2/10$767

Find flight deals from Panama City to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$686
(United Airlines)

One-way from

$397
(United Airlines)

Popular in

January

Cheapest in

August

Average price

$622
Provider with most accurate pricing for Panama City Tocumen Intl-Santa Ana J. Wayne/Orange Cnty flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Santa Ana J. Wayne/Orange Cnty flights.
Search Deals
From Panama City Tocumen Intl to Santa Ana J. Wayne/Orange Cnty
Search Deals
One-way flight from Panama City Tocumen Intl to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($38 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 10, 2026.
Use the filters below to find and compare flights from Panama City to Santa Ana that are best for you.

Fly from

Panama City

Fly to

Santa Ana

Route

Depart

Return

Price

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Tue 7/28

7:55 am-9:36 pm

1 stop15h 41m

Santa Ana J. Wayne/Orange Cnty

Thu 7/30

7:54 am-6:37 pm

1 stop8h 43m

$686

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Tue 7/28

3:30 pm-10:58 am

1 stop21h 28m

Santa Ana J. Wayne/Orange Cnty

Wed 8/5

7:54 am-6:37 pm

1 stop8h 43m

$686

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Mon 7/27

7:55 am-9:36 pm

1 stop15h 41m

Santa Ana J. Wayne/Orange Cnty

Tue 8/4

4:12 pm-2:14 pm

2 stops20h 02m

$686

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Mon 7/27

7:55 am-9:36 pm

1 stop15h 41m

Santa Ana J. Wayne/Orange Cnty

Thu 7/30

7:54 am-6:37 pm

1 stop8h 43m

$686

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Thu 7/23

10:00 am-9:36 pm

1 stop13h 36m

Santa Ana J. Wayne/Orange Cnty

Tue 8/4

7:55 pm-6:37 pm

2 stops20h 42m

$686

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Wed 7/29

7:55 am-10:01 pm

2 stops16h 06m

Santa Ana J. Wayne/Orange Cnty

Mon 8/3

4:00 pm-2:14 pm

2 stops20h 14m

$686

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Wed 3/25

7:55 am-9:45 pm

1 stop15h 50m

Santa Ana J. Wayne/Orange Cnty

Wed 4/1

3:29 pm-6:37 pm

1 stop25h 08m

$696

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sat 7/25

7:55 am-9:36 pm

1 stop15h 41m

Santa Ana J. Wayne/Orange Cnty

Mon 8/3

6:26 pm-2:14 pm

2 stops17h 48m

$707

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Thu 3/26

3:41 pm-11:27 am

1 stop21h 46m

Santa Ana J. Wayne/Orange Cnty

Mon 4/6

6:28 pm-6:37 pm

2 stops22h 09m

$707

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Mon 7/27

10:00 am-9:36 pm

1 stop13h 36m

$397

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/10

Showing 1-10 of 17 results
1
2
  • Most accurate provider: When it comes to deals on Panama City-Santa Ana flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Santa Ana flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Santa Ana flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Santa Ana flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Santa Ana flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Santa Ana

What is the cheapest month to book a flight from Panama City to Santa Ana?

Currently, May is the cheapest month in which you can book a flight from Panama City to Santa Ana (average of $223). Flying from Panama City to Santa Ana in January is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Santa Ana?

    For as low as $686, United Airlines can have you in Santa Ana from Panama City in 15h 41m. Airlines will cover a distance of 2973 mi.

  • Can I find deals for flights from Panama City to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Panama City to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Santa Ana.

  • Can I find deals for business class flights from Panama City to Santa Ana?

    Yes. Cheapflights offers flight deals from Panama City to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Santa Ana?

    Currently, May is the cheapest month in which you can book a flight from Panama City to Santa Ana (average of $223). Flying from Panama City to Santa Ana in January is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
Tustin

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