How long is the flight from Missouri to Santa Ana, California?

Airlines like Spirit Airlines, Frontier, and United Airlines fly from Missouri to Santa Ana, California in about 6h 06m. The time it takes to get you to your destination can typically vary by up to 19h 29m. The distance between Missouri and Santa Ana, California is about 1466 mi. Both multi-stop and nonstop flights can be found to your destination and back.

In terms of precipitation, rainfall in Santa Ana, California ranges from 0.0 - 3.1 inches per month. February is typically the wettest month, when rainfall can reach 3.1 in. July is typically the driest time to visit Santa Ana, California when rainfall is around 0.0 in.

If weather is an important factor for your trip to Santa Ana, California, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What are the most popular routes from Missouri to Santa Ana, California?

The most popular flight routes from Missouri to Santa Ana, California are Kansas City - Santa Ana J. Wayne/Orange Cnty, Lambert-St Louis - Santa Ana J. Wayne/Orange Cnty and Springfield-Branson - Santa Ana J. Wayne/Orange Cnty.

What airport do you fly into for flights to Santa Ana from Missouri?

Located just 4.8 mi from the city center, Santa Ana J. Wayne/Orange Cnty (SNA) is the airport most travelers will use when flying to Santa Ana from Missouri.

Can I find deals for flights from Missouri to Santa Ana that include hotel bookings?

Yes. In addition to deals on Missouri to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Santa Ana?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Santa Ana.

Can I find deals for business class flights from Missouri to Santa Ana?

Yes. Cheapflights offers flight deals from Missouri to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$62+ Flights from Missouri to Santa Ana, CA

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Cheap flight deals from Missouri to Santa Ana

Most accurate provider	Justfly.com 3 stars
Most trusted provider	Justfly.com 3 stars
Round-trip from	$123 (CheapOair)
One-way from	$62 (CheapOair)
Popular in	March
Cheapest in	September
Average price	$372

Provider with most accurate pricing for Lambert-St Louis-Los Angeles flight deals.

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Provider most trusted by Cheapflights users for Lambert-St Louis-Los Angeles flights.

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From Missouri to Santa Ana J. Wayne/Orange Cnty

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One-way flight from Missouri to Santa Ana J. Wayne/Orange Cnty

Search Deals

Highest demand for flights based on searches. 3% potential increase in price ($14 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).

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Average for round-trip flights in October 2025

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Find flight deals from Missouri to Santa Ana

Cheapest flights from Missouri to Santa Ana
Explore the most affordable flight options available from Missouri to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

Wed 11/127:45 pmSTL - SNA

1 stop17h 31mFrontier

Sat 11/152:20 pmSNA - STL

1 stop16h 47mFrontier

Deal found 10/28

$130

Fri 12/52:48 pmMCI - SNA

1 stop23h 54mMultiple Airlines

Tue 12/911:39 amSNA - MCI

1 stop7h 05mMultiple Airlines

Deal found 10/30

$134

Fri 11/142:42 pmSTL - SNA

1 stop6h 06mFrontier

Tue 11/183:01 pmSNA - STL

1 stop16h 06mFrontier

Deal found 10/30

$137

Thu 11/137:45 pmSTL - SNA

1 stop17h 31mFrontier

Mon 11/1712:01 pmSNA - STL

1 stop19h 06mFrontier

Deal found 10/29

$150

Fri 12/510:44 pmSTL - SNA

1 stop14h 00mMultiple Airlines

Tue 12/91:35 pmSNA - STL

1 stop18h 39mMultiple Airlines

Deal found 10/29

$169

Tue 12/166:30 amMCI - SNA

1 stop6h 14mSpirit Airlines

Thu 12/186:45 amSNA - MCI

1 stop6h 07mSpirit Airlines

Deal found 10/28

$171

Thu 12/116:30 amMCI - SNA

1 stop6h 14mSpirit Airlines

Tue 12/166:45 amSNA - MCI

1 stop11h 59mSpirit Airlines

Deal found 10/28

$173

Mon 12/86:30 amMCI - SNA

1 stop6h 14mSpirit Airlines

Wed 12/106:45 amSNA - MCI

1 stop11h 59mSpirit Airlines

Deal found 10/28

$176

Mon 11/102:42 pmSTL - SNA

1 stop6h 06mFrontier

Wed 11/123:01 pmSNA - STL

1 stop16h 06mFrontier

Deal found 10/29

$176

Fri 12/126:30 amMCI - SNA

1 stop6h 14mMultiple Airlines

Sun 12/1411:15 amSNA - MCI

1 stop6h 35mMultiple Airlines

Deal found 10/30

$177

Tue 12/212:58 pmMCI - SNA

1 stop10h 08mSpirit Airlines

Tue 12/96:45 amSNA - MCI

1 stop11h 59mSpirit Airlines

Deal found 10/29

$178

Thu 12/48:09 pmMCI - SNA

1 stop18h 33mMultiple Airlines

Wed 12/1011:39 amSNA - MCI

1 stop25h 13mMultiple Airlines

Deal found 10/30

$179

Best flights from Missouri to Santa Ana
Discover carefully curated flight deals from Missouri to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2025.

Mon 12/156:30 amMCI - SNA

1 stop6h 14mSpirit Airlines

Thu 12/186:45 amSNA - MCI

1 stop6h 07mSpirit Airlines

Deal found 10/28

$173

Fri 1/97:43 pmSTL - SNA

1 stop18h 39mMultiple Airlines

Wed 1/145:46 pmSNA - STL

2 stops14h 00mMultiple Airlines

Deal found 10/29

$176

Fri 12/122:48 pmMCI - SNA

2 stops25h 35mFrontier

Sun 12/1411:15 amSNA - MCI

1 stop6h 35mFrontier

Deal found 10/30

$183

Sat 1/107:00 amSTL - SNA

2 stops13h 17mDelta

Wed 1/147:30 amSNA - STL

2 stops12h 05mDelta

Deal found 10/30

$334

Wed 12/109:00 amCOU - SNA

1 stop6h 06mUnited Airlines

Sat 12/136:45 amSNA - COU

1 stop8h 26mUnited Airlines

Deal found 10/28

$338

Fri 2/201:20 pmSTL - SNA

1 stop6h 55mSouthwest

Mon 2/238:55 amSNA - STL

2 stops6h 55mSouthwest

Deal found 10/29

$340

Wed 2/182:23 pmSGF - SNA

2 stops9h 36mAmerican Airlines

Sat 2/217:45 amSNA - SGF

1 stop6h 40mAmerican Airlines

Deal found 10/30

$354

Thu 12/48:09 pmMCI - SNA

1 stop18h 33mMultiple Airlines

Wed 12/1011:39 amSNA - MCI

1 stop25h 13mMultiple Airlines

Deal found 10/30

$179

Wed 11/191:23 pmMCI - SNA

1 stop9h 38mSpirit Airlines

Mon 11/241:27 pmSNA - MCI

1 stop4h 36mSpirit Airlines

Deal found 10/29

$194

Thu 11/279:54 pmSTL - SNA

1 stop20h 05mFrontier

Thu 12/46:34 pmSNA - STL

1 stop15h 38mFrontier

Deal found 10/30

$206

Mon 12/86:30 amMCI - SNA

1 stop13h 09mMultiple Airlines

Wed 12/1011:39 amSNA - MCI

2 stops29h 35mMultiple Airlines

Deal found 10/28

$194

Fri 11/142:42 pmSTL - SNA

1 stop8h 19mMultiple Airlines

Mon 11/171:31 pmSNA - STL

2 stops17h 36mMultiple Airlines

Deal found 10/30

$196

Mon 11/2412:58 pmMCI - SNA

1 stop5h 53mSpirit Airlines

Fri 11/286:45 amSNA - MCI

1 stop11h 18mSpirit Airlines

Deal found 10/29

$217

Sun 1/117:00 amMCI - SNA

1 stop11h 51mMultiple Airlines

Wed 1/145:46 pmSNA - MCI

2 stops24h 05mMultiple Airlines

Deal found 10/29

$202

Tue 11/116:49 pmMCI - SNA

1 stop20h 41mFrontier

Tue 11/2512:04 pmSNA - MCI

1 stop5h 30mFrontier

Deal found 10/28

$254

Sun 1/111:45 pmMCI - SNA

3 stops29h 06mSpirit Airlines

Wed 1/147:15 amSNA - MCI

1 stop15h 25mSpirit Airlines

Deal found 10/29

$261

Fri 11/148:28 pmMCI - SNA

1 stop19h 07mFrontier

Tue 11/183:01 pmSNA - MCI

1 stop24h 18mFrontier

Deal found 10/30

$265

Tue 1/67:00 amSTL - SNA

2 stops11h 14mDelta

Sat 1/1011:20 amSNA - STL

2 stops10h 05mDelta

Deal found 10/30

$334

Tue 11/119:00 amCOU - SNA

2 stops11h 18mUnited Airlines

Sat 12/1311:10 amSNA - COU

2 stops8h 12mUnited Airlines

Deal found 10/30

$339

Thu 11/137:45 pmSTL - SNA

2 stops27h 16mMultiple Airlines

Mon 11/1712:01 pmSNA - STL

1 stop19h 06mMultiple Airlines

Deal found 10/29

$242

Wed 11/197:45 pmSTL - SNA

1 stop17h 34mFrontier

Sun 11/2310:07 amSNA - STL

2 stops30h 12mFrontier

Deal found 10/30

$268

Fri 12/55:34 pmSTL - SNA

2 stops18h 43mDelta

Wed 12/106:50 pmSNA - STL

2 stops12h 20mDelta

Deal found 10/29

$334

Sat 3/76:02 pmJLN - SNA

1 stop6h 14mUnited Airlines

Wed 3/117:00 amSNA - JLN

1 stop8h 24mUnited Airlines

Deal found 10/28

$344

Sun 12/218:45 pmMCI - SNA

1 stop16h 23mFrontier

Sun 12/287:57 pmSNA - MCI

2 stops21h 53mFrontier

Deal found 10/28

$270

Fri 11/144:02 pmSGF - SNA

1 stop8h 17mDelta

Tue 11/1812:45 pmSNA - SGF

1 stop7h 28mDelta

Deal found 10/30

$339

Tue 11/116:49 pmMCI - SNA

2 stops28h 12mMultiple Airlines

Tue 11/2512:04 pmSNA - MCI

1 stop5h 30mMultiple Airlines

Deal found 10/28

$265

Wed 1/73:14 pmSGF - SNA

1 stop9h 10mUnited Airlines

Wed 1/149:00 amSNA - SGF

2 stops10h 58mUnited Airlines

Deal found 10/29

$354

Tue 11/116:32 amCOU - SNA

1 stop8h 11mAmerican Airlines

Sat 12/138:30 amSNA - COU

1 stop7h 13mAmerican Airlines

Deal found 10/30

$447

Mon 11/247:43 pmSTL - SNA

1 stop17h 36mFrontier

Tue 12/21:35 pmSNA - STL

1 stop18h 39mFrontier

Deal found 10/30

$282

Wed 12/106:00 amSTL - SNA

1 stop9h 00mDelta

Wed 12/105:20 pmSNA - STL

1 stop5h 41mDelta

Deal found 10/29

$343

Last-minute flights from Missouri to Santa Ana
Discover last-minute flight deals from Missouri to Santa Ana. Data last updated October 30, 2025 and is based on user searches.

Mon 11/102:42 pmSTL - SNA

1 stop6h 06mFrontier

Wed 11/123:01 pmSNA - STL

1 stop16h 06mFrontier

Deal found 10/29

$176

Tue 11/111:23 pmMCI - SNA

1 stop9h 38mSpirit Airlines

Thu 11/206:45 amSNA - MCI

1 stop11h 18mSpirit Airlines

Deal found 10/29

$207

Wed 11/127:45 pmSTL - SNA

1 stop17h 31mFrontier

Sat 11/152:20 pmSNA - STL

1 stop16h 47mFrontier

Deal found 10/28

$130

Thu 11/137:45 pmSTL - SNA

1 stop17h 31mFrontier

Mon 11/1712:01 pmSNA - STL

1 stop19h 06mFrontier

Deal found 10/29

$150

Fri 11/142:42 pmSTL - SNA

1 stop6h 06mFrontier

Tue 11/183:01 pmSNA - STL

1 stop16h 06mFrontier

Deal found 10/30

$137

Fri 11/147:45 pmSTL - SNA

1 stop19h 50mFrontier

Mon 11/1712:01 pmSNA - STL

1 stop19h 06mFrontier

Deal found 10/30

$183

Fri 11/142:42 pmSTL - SNA

1 stop8h 19mMultiple Airlines

Mon 11/171:31 pmSNA - STL

2 stops17h 36mMultiple Airlines

Deal found 10/30

$196

Fri 11/142:42 pmSTL - SNA

1 stop8h 19mMultiple Airlines

Tue 11/181:31 pmSNA - STL

2 stops17h 36mMultiple Airlines

Deal found 10/30

$204

Tue 11/186:49 pmMCI - SNA

2 stops28h 12mMultiple Airlines

Fri 11/2110:58 amSNA - MCI

1 stop7h 05mMultiple Airlines

Deal found 10/30

$193

Tue 11/187:45 pmSTL - SNA

2 stops18h 51mMultiple Airlines

Thu 11/206:45 amSNA - STL

1 stop12h 24mMultiple Airlines

Deal found 10/29

$208

Wed 11/191:23 pmMCI - SNA

1 stop9h 38mSpirit Airlines

Mon 11/241:27 pmSNA - MCI

1 stop4h 36mSpirit Airlines

Deal found 10/29

$192

Thu 11/279:54 pmSTL - SNA

1 stop20h 05mFrontier

Thu 12/46:34 pmSNA - STL

1 stop15h 38mFrontier

Deal found 10/30

$206

One-way flights from Missouri to Santa Ana
Search for one-way flight options from Missouri to Santa Ana. Find affordable one-way fares based on user searches. Data last updated October 30, 2025.

Tue 1/137:00 amMCI - SNA

1 stop11h 51mSpirit Airlines

Deal found 10/30

$62

Mon 11/172:42 pmSTL - SNA

1 stop6h 06mFrontier

Deal found 10/30

$65

Sat 11/157:45 pmSTL - SNA

1 stop17h 31mFrontier

Deal found 10/30

$71

Fri 12/512:07 pmSTL - SNA

1 stop5h 48mFrontier

Deal found 10/30

$72

Sun 12/79:14 pmSTL - SNA

1 stop22h 25mFrontier

Deal found 10/30

$75

Sat 12/67:43 pmSTL - SNA

1 stop18h 59mFrontier

Deal found 10/30

$78

Thu 1/297:00 amMCI - SNA

1 stop11h 51mSpirit Airlines

Deal found 10/30

$81

Tue 12/96:30 amMCI - SNA

1 stop6h 14mSpirit Airlines

Deal found 10/30

$83

Wed 1/77:00 amMCI - SNA

1 stop5h 16mSpirit Airlines

Deal found 10/30

$84

Thu 12/116:30 amMCI - SNA

1 stop6h 14mSpirit Airlines

Deal found 10/30

$85

Thu 11/132:42 pmSTL - SNA

1 stop6h 49mFrontier

Deal found 10/29

$85

Sat 1/107:00 amMCI - SNA

1 stop11h 51mSpirit Airlines

Deal found 10/30

$86

Fly from

Fly to

Route

Depart

Return

Price

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Mon 12/15

6:30 am-10:44 am

1 stop6h 14m

Santa Ana J. Wayne/Orange Cnty

Thu 12/18

6:45 am-2:52 pm

1 stop6h 07m

$173

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Fri 1/9

7:43 pm-12:22 pm

1 stop18h 39m

Santa Ana J. Wayne/Orange Cnty

Wed 1/14

5:46 pm-9:46 am

2 stops14h 00m

$176

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Thu 12/4

8:09 pm-12:42 pm

1 stop18h 33m

Santa Ana J. Wayne/Orange Cnty

Wed 12/10

11:39 am-2:52 pm

1 stop25h 13m

$179

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Fri 12/12

2:48 pm-2:23 pm

2 stops25h 35m

Santa Ana J. Wayne/Orange Cnty

Sun 12/14

11:15 am-7:50 pm

1 stop6h 35m

$183

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Wed 11/19

1:23 pm-9:01 pm

1 stop9h 38m

Santa Ana J. Wayne/Orange Cnty

Mon 11/24

1:27 pm-8:03 pm

1 stop4h 36m

$194

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Mon 12/8

6:30 am-5:39 pm

1 stop13h 09m

Santa Ana J. Wayne/Orange Cnty

Wed 12/10

11:39 am-7:14 pm

2 stops29h 35m

$194

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Fri 11/14

2:42 pm-9:01 pm

1 stop8h 19m

Santa Ana J. Wayne/Orange Cnty

Mon 11/17

1:31 pm-9:07 am

2 stops17h 36m

$196

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Sun 1/11

7:00 am-4:51 pm

1 stop11h 51m

Santa Ana J. Wayne/Orange Cnty

Wed 1/14

5:46 pm-7:51 pm

2 stops24h 05m

$202

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 11/27

9:54 pm-3:59 pm

1 stop20h 05m

Santa Ana J. Wayne/Orange Cnty

Thu 12/4

6:34 pm-12:12 pm

1 stop15h 38m

$206

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Mon 11/24

12:58 pm-4:51 pm

1 stop5h 53m

Santa Ana J. Wayne/Orange Cnty

Fri 11/28

6:45 am-8:03 pm

1 stop11h 18m

$217

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 60 results

...

Best time to book a flight from Missouri to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Santa Ana

What is the cheapest month to book a flight from Missouri to Santa Ana, California?

Currently, November is the cheapest month in which you can book a flight from Missouri to Santa Ana, California (average of $67). Flying from Missouri to Santa Ana, California in March is currently the most expensive (average of $146). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SNA?

One of the essential ways to save on airfare from Missouri to Santa Ana, California is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 61% on airfare.

What is the cheapest day to fly from Missouri to Santa Ana, California?

Travelers seeking maximum savings on their Missouri to Santa Ana, California flight should consider departing on Friday evenings when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

What airport do you fly into for flights to Santa Ana from Missouri?
Located just 4.8 mi from the city center, Santa Ana J. Wayne/Orange Cnty (SNA) is the airport most travelers will use when flying to Santa Ana from Missouri.
How long is the flight from Missouri to Santa Ana, California?
Airlines like Spirit Airlines, Frontier, and United Airlines fly from Missouri to Santa Ana, California in about 6h 06m. The time it takes to get you to your destination can typically vary by up to 19h 29m. The distance between Missouri and Santa Ana, California is about 1466 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the most popular routes from Missouri to Santa Ana, California?
The most popular flight routes from Missouri to Santa Ana, California are Kansas City - Santa Ana J. Wayne/Orange Cnty, Lambert-St Louis - Santa Ana J. Wayne/Orange Cnty and Springfield-Branson - Santa Ana J. Wayne/Orange Cnty.
Can I find deals for flights from Missouri to Santa Ana that include hotel bookings?
Yes. In addition to deals on Missouri to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Santa Ana?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Santa Ana.
Can I find deals for business class flights from Missouri to Santa Ana?
Yes. Cheapflights offers flight deals from Missouri to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Santa Ana, California?
Currently, November is the cheapest month in which you can book a flight from Missouri to Santa Ana, California (average of $67). Flying from Missouri to Santa Ana, California in March is currently the most expensive (average of $146). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 6 airlines flying from Missouri to Santa Ana

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$88	Average$250	FlexibilityNo cancel fee	On-time65%
Frontier	Cheapest$144	Average$218	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$203	Average$392	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$264	Average$403	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$268	Average$451	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$303	Average$442	FlexibilityNo cancel fee	On-time63%

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$62+ Cheap flights from Missouri to Santa Ana, CA (SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Missouri to Santa Ana

Keep the following information in mind while searching for Missouri to Santa Ana flight deals. Data was last updated October 30, 2025.

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Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Missouri to Santa Ana

Cheapest flights from Missouri to Santa AnaExplore the most affordable flight options available from Missouri to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

Explore the most affordable flight options available from Missouri to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Santa Ana that are best for you.

Best time to book a flight from Missouri to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Santa Ana

What is the cheapest month to book a flight from Missouri to Santa Ana, California?

What is the cheapest time of day to fly from MO to SNA?

Find hourly flight availability from Missouri to Santa Ana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

What is the cheapest day to fly from Missouri to Santa Ana, California?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Santa Ana. Price data was last updated on December 16, 2024.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santa Ana from Missouri?

How long is the flight from Missouri to Santa Ana, California?

What are the most popular routes from Missouri to Santa Ana, California?

Can I find deals for flights from Missouri to Santa Ana that include hotel bookings?

How can I find direct flights from Missouri to Santa Ana?

Can I find deals for business class flights from Missouri to Santa Ana?

What is the cheapest month to book a flight from Missouri to Santa Ana, California?

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Alternative routes for Missouri to Santa Ana

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Top 6 airlines flying from Missouri to Santa Ana

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Cheapest flights from Missouri to Santa Ana
Explore the most affordable flight options available from Missouri to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.