What are the cheapest airlines to fly from Missouri to Santa Ana one-way?

One-way options have recently been found by users for as low as $85 on Spirit Airlines. Other airlines that offer cheap prices include Frontier from $100 and Delta from $144 one-way.

What are the most popular routes from Missouri to Santa Ana?

The most popular flight routes from Missouri to Santa Ana are Lambert-St Louis - Santa Ana J. Wayne/Orange Cnty, Kansas City - Santa Ana J. Wayne/Orange Cnty and Springfield-Branson - Santa Ana J. Wayne/Orange Cnty.

What are the most popular airlines that fly from Missouri to Santa Ana?

Before booking your flight from Missouri to Santa Ana check out the most popular airlines for this route: American Airlines, Delta or Frontier.

How far in advance should I book a flight from Missouri to Santa Ana?

Travelers have found it’s best to book a flight 38 days in advance to save up to 88% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 38 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from Missouri to Santa Ana 1-2 weeks in advance for as low as $230, or $400 for flights within the next 24 hours.

What is the cheapest month to fly from Missouri to Santa Ana?

Due to multiple factors, expect to potentially pay more when booking in March. For low rates, September can be a great choice for travel to Santa Ana. Flights to Santa Ana from Missouri in September are about $274 on average during September, but can be found for as low as $63.

What airport do you fly into for flights to Santa Ana from Missouri?

Located just 4.8 mi from the city center, Santa Ana J. Wayne/Orange Cnty (SNA) is the airport most travelers will use when flying to Santa Ana from Missouri.

Can I find deals for flights from Missouri to Santa Ana that include hotel bookings?

Yes. In addition to deals on Missouri to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Santa Ana?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Santa Ana.

Can I find deals for business class flights from Missouri to Santa Ana?

Yes. Cheapflights offers flight deals from Missouri to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$85+ Flights from Missouri to Santa Ana

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Cheap flight deals from Missouri to Santa Ana

Most accurate provider	Mytrip 3 stars
Most trusted provider	Mytrip 3 stars
Round-trip from	$181 (CheapOair)
One-way from	$85 (Mytrip)
Popular in	March
Cheapest in	September
Average price	$211

Provider with most accurate pricing for Kansas City-Los Angeles flight deals.

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Provider most trusted by Cheapflights users for Kansas City-Los Angeles flights.

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From Missouri to Santa Ana J. Wayne/Orange Cnty

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One-way flight from Missouri to Santa Ana J. Wayne/Orange Cnty

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Highest demand for flights based on searches. 22% potential increase in price ($80 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($11 potential savings vs. average RT price).

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Average for round-trip flights in May 2025

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Find flight deals from Missouri to Santa Ana

Cheapest flights from Missouri to Santa Ana
Explore the most affordable flight options available from Missouri to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Mon 6/27:58 pmMCI - SNA

1 stop20h 23mSpirit Airlines

Thu 6/56:45 amSNA - MCI

1 stop10h 18mSpirit Airlines

Deal found 4/29

$195

Thu 5/158:51 pmMCI - SNA

1 stop16h 37mMultiple Airlines

Tue 5/206:45 amSNA - MCI

1 stop9h 00mMultiple Airlines

Deal found 4/29

$205

Fri 5/307:51 pmMCI - SNA

1 stop17h 20mFrontier

Wed 6/412:01 pmSNA - MCI

1 stop5h 10mFrontier

Deal found 4/28

$211

Fri 5/237:24 pmSTL - SNA

1 stop17h 47mFrontier

Tue 6/312:04 pmSNA - STL

1 stop20h 04mFrontier

Deal found 4/30

$260

Tue 10/73:05 pmSGF - SNA

1 stop8h 36mUnited Airlines

Wed 10/298:00 amSNA - SGF

1 stop5h 53mUnited Airlines

Deal found 4/29

$269

Wed 10/16:00 amMCI - SNA

2 stops8h 11mUnited Airlines

Sat 10/48:40 amSNA - MCI

1 stop5h 29mUnited Airlines

Deal found 4/29

$292

Wed 5/282:29 pmSTL - SNA

2 stops9h 58mDelta

Mon 6/26:55 pmSNA - STL

2 stops13h 52mDelta

Deal found 4/30

$306

Sun 6/110:10 amSTL - SNA

2 stops26h 42mSpirit Airlines

Fri 6/66:45 amSNA - STL

2 stops24h 30mSpirit Airlines

Deal found 4/30

$334

Mon 5/199:50 amSTL - SNA

3 stops37h 27mMultiple Airlines

Wed 5/284:27 pmSNA - STL

2 stops14h 48mMultiple Airlines

Deal found 4/30

$335

Tue 9/234:55 pmMCI - SNA

1 stop7h 22mAlaska Airlines

Fri 9/267:00 amSNA - MCI

1 stop7h 01mAlaska Airlines

Deal found 4/29

$337

Mon 7/75:50 amMCI - SNA

1 stop5h 15mAmerican Airlines

Sat 7/123:07 pmSNA - MCI

1 stop6h 52mAmerican Airlines

Deal found 4/29

$338

Sat 9/202:55 pmSTL - SNA

1 stop8h 10mSouthwest

Tue 9/232:00 pmSNA - STL

1 stop5h 30mSouthwest

Deal found 4/30

$344

Best flights from Missouri to Santa Ana
Discover carefully curated flight deals from Missouri to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2025.

Wed 5/78:15 pmSTL - SNA

1 stop17h 09mFrontier

Tue 5/2012:19 pmSNA - STL

1 stop19h 40mFrontier

Deal found 4/28

$181

Tue 5/206:45 pmMCI - SNA

1 stop21h 36mSpirit Airlines

Thu 5/296:45 amSNA - MCI

1 stop10h 18mSpirit Airlines

Deal found 4/30

$194

Thu 5/158:51 pmMCI - SNA

1 stop16h 37mMultiple Airlines

Tue 5/206:45 amSNA - MCI

1 stop9h 00mMultiple Airlines

Deal found 4/30

$240

Tue 10/73:05 pmSGF - SNA

1 stop8h 36mUnited Airlines

Wed 10/298:00 amSNA - SGF

1 stop5h 53mUnited Airlines

Deal found 4/29

$269

Wed 5/216:45 amMCI - SNA

1 stop7h 10mDelta

Tue 5/275:01 pmSNA - MCI

1 stop5h 19mDelta

Deal found 4/30

$287

Mon 7/75:50 amMCI - SNA

1 stop5h 15mAmerican Airlines

Sat 7/123:07 pmSNA - MCI

1 stop6h 52mAmerican Airlines

Deal found 4/29

$338

Wed 7/304:50 pmMCI - SNA

1 stop6h 35mSouthwest

Fri 8/17:05 amSNA - MCI

2 stops8h 20mSouthwest

Deal found 4/29

$388

Mon 5/123:59 pmMCI - SNA

1 stop8h 29mAlaska Airlines

Wed 8/207:00 amSNA - MCI

1 stop7h 01mAlaska Airlines

Deal found 4/30

$392

Wed 5/287:30 amSTL - SNA

2 stops12h 31mDelta

Mon 6/26:55 pmSNA - STL

2 stops13h 52mDelta

Deal found 4/29

$306

Sun 6/13:03 pmSTL - SNA

1 stop9h 27mHawaiian Airlines

Fri 6/61:30 pmSNA - STL

1 stop8h 34mHawaiian Airlines

Deal found 4/29

$648

Sun 6/110:10 amSTL - SNA

2 stops26h 42mSpirit Airlines

Fri 6/66:45 amSNA - STL

2 stops24h 30mSpirit Airlines

Deal found 4/30

$334

Sun 6/11:00 pmSTL - SNA

3 stops34h 17mMultiple Airlines

Fri 6/66:45 amSNA - STL

2 stops24h 30mMultiple Airlines

Deal found 4/30

$337

Last-minute flights from Missouri to Santa Ana
Discover last-minute flight deals from Missouri to Santa Ana. Data last updated May 1, 2025 and is based on user searches.

Tue 5/65:27 amSGF - SNA

1 stop6h 34mAmerican Airlines

Tue 5/134:46 pmSNA - SGF

1 stop5h 08mAmerican Airlines

Deal found 4/29

$349

Tue 5/69:50 amSTL - SNA

3 stops30h 31mMultiple Airlines

Thu 5/87:58 pmSNA - STL

2 stops35h 17mMultiple Airlines

Deal found 4/29

$400

Tue 5/65:10 pmSGF - SNA

1 stop6h 50mUnited Airlines

Tue 5/139:52 amSNA - SGF

2 stops11h 38mUnited Airlines

Deal found 4/29

$434

Tue 5/62:19 pmSTL - SNA

1 stop5h 56mAmerican Airlines

Thu 5/810:25 amSNA - STL

1 stop5h 56mAmerican Airlines

Deal found 4/29

$437

Tue 5/66:00 amSGF - SNA

2 stops14h 13mDelta

Tue 5/1312:17 pmSNA - SGF

1 stop8h 00mDelta

Deal found 4/30

$486

Tue 5/69:40 amSTL - SNA

2 stops9h 35mUnited Airlines

Thu 5/812:12 pmSNA - STL

1 stop7h 51mUnited Airlines

Deal found 4/29

$532

Tue 5/63:08 pmSTL - SNA

1 stop22h 08mAlaska Airlines

Fri 5/97:10 pmSNA - STL

1 stop16h 58mAlaska Airlines

Deal found 4/30

$643

Wed 5/78:15 pmSTL - SNA

1 stop17h 09mFrontier

Tue 5/2012:19 pmSNA - STL

1 stop19h 40mFrontier

Deal found 4/28

$181

Wed 5/75:15 amMCI - SNA

1 stop8h 26mAmerican Airlines

Fri 5/92:45 pmSNA - MCI

1 stop6h 06mAmerican Airlines

Deal found 4/30

$437

Wed 5/711:40 amMCI - SNA

2 stops8h 29mUnited Airlines

Fri 5/93:36 pmSNA - MCI

1 stop6h 08mUnited Airlines

Deal found 4/30

$522

Thu 5/88:51 pmMCI - SNA

1 stop16h 37mFrontier

Mon 5/1212:51 pmSNA - MCI

1 stop5h 00mFrontier

Deal found 4/28

$241

Sat 5/102:45 pmMCI - SNA

2 stops25h 36mSpirit Airlines

Wed 5/146:45 amSNA - MCI

1 stop9h 00mSpirit Airlines

Deal found 4/30

$278

One-way flights from Missouri to Santa Ana
Search for one-way flight options from Missouri to Santa Ana. Find affordable one-way fares based on user searches. Data last updated May 1, 2025.

Fri 5/237:58 pmMCI - SNA

1 stop27h 19mSpirit Airlines

Deal found 4/30

$85

Sun 5/119:55 pmSTL - SNA

1 stop22h 41mFrontier

Deal found 4/30

$100

Mon 5/198:51 pmMCI - SNA

1 stop16h 37mFrontier

Deal found 4/30

$140

Tue 6/176:40 amMCI - SNA

1 stop7h 12mDelta

Deal found 4/29

$144

Wed 5/215:20 amSTL - SNA

2 stops8h 58mUnited Airlines

Deal found 4/30

$169

Wed 6/1112:15 pmSTL - SNA

3 stops21h 01mMultiple Airlines

Deal found 4/30

$174

Sat 7/126:05 amMCI - SNA

2 stops11h 04mUnited Airlines

Deal found 4/30

$189

Sun 5/185:19 amSTL - SNA

1 stop6h 42mAmerican Airlines

Deal found 4/30

$201

Fri 5/96:30 amSTL - SNA

1 stop9h 49mAlaska Airlines

Deal found 4/29

$218

Thu 7/242:55 pmSTL - SNA

2 stops8h 10mSouthwest

Deal found 4/30

$219

Sun 6/296:00 amSTL - SNA

1 stop9h 25mDelta

Deal found 4/29

$224

Thu 6/195:25 amMCI - SNA

1 stop5h 55mAmerican Airlines

Deal found 4/30

$235

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Mon 6/2

7:58 pm-2:21 pm

1 stop20h 23m

Santa Ana J. Wayne/Orange Cnty

Thu 6/5

6:45 am-7:03 pm

1 stop10h 18m

$195

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Thu 5/15

8:51 pm-11:28 am

1 stop16h 37m

Santa Ana J. Wayne/Orange Cnty

Tue 5/20

6:45 am-5:45 pm

1 stop9h 00m

$205

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Fri 5/30

7:51 pm-11:11 am

1 stop17h 20m

Santa Ana J. Wayne/Orange Cnty

Wed 6/4

12:01 pm-7:11 pm

1 stop5h 10m

$211

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Fri 5/23

7:24 pm-11:11 am

1 stop17h 47m

Santa Ana J. Wayne/Orange Cnty

Tue 6/3

12:04 pm-10:08 am

1 stop20h 04m

$260

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Wed 10/1

6:00 am-12:11 pm

2 stops8h 11m

Santa Ana J. Wayne/Orange Cnty

Sat 10/4

8:40 am-4:09 pm

1 stop5h 29m

$292

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 5/28

2:29 pm-10:27 pm

2 stops9h 58m

Santa Ana J. Wayne/Orange Cnty

Mon 6/2

6:55 pm-10:47 am

2 stops13h 52m

$306

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Sun 6/1

10:10 am-10:52 am

2 stops26h 42m

Santa Ana J. Wayne/Orange Cnty

Fri 6/6

6:45 am-9:15 am

2 stops24h 30m

$334

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Mon 5/19

9:50 am-9:17 pm

3 stops37h 27m

Santa Ana J. Wayne/Orange Cnty

Wed 5/28

4:27 pm-9:15 am

2 stops14h 48m

$335

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Tue 9/23

4:55 pm-10:17 pm

1 stop7h 22m

Santa Ana J. Wayne/Orange Cnty

Fri 9/26

7:00 am-4:01 pm

1 stop7h 01m

$337

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Mon 7/7

5:50 am-9:05 am

1 stop5h 15m

Santa Ana J. Wayne/Orange Cnty

Sat 7/12

3:07 pm-11:59 pm

1 stop6h 52m

$338

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 40 results

Best time to book a flight from Missouri to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Santa Ana

What is the cheapest month to book a flight from Missouri to Santa Ana?

Currently, January is the cheapest month in which you can book a flight from Missouri to Santa Ana (average of $298). Flying from Missouri to Santa Ana in June is currently the most expensive (average of $395). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SNA?

When flying from Missouri to Santa Ana, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Santa Ana by month

In terms of precipitation, rainfall in Santa Ana ranges from 0.0 - 3.1 inches per month. February is typically the wettest month, when rainfall can reach 3.1 in. July is typically the driest time to visit Santa Ana when rainfall is around 0.0 in.

Temperature in Santa Ana by month

If weather is an important factor for your trip to Santa Ana, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Santa Ana

To help decide which airline to fly from Missouri to Santa Ana, see what other customers have to say about Alaska Airlines, Southwest and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

8.0

Very good

9,972 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Alaska Airlines

8.0

Very good

9,972 reviews

Alaska Airlines

8.0

Very good

9,972 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Southwest

8.0

Very good

4,294 reviews

Alaska Airlines

8.0

Very good

9,972 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Delta

8.0

Very good

7,934 reviews

Alaska Airlines

8.0

Very good

9,972 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Hawaiian Airlines

7.9

Good

2,408 reviews

Alaska Airlines

8.0

Very good

9,972 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

United Airlines

7.4

Good

8,696 reviews

Alaska Airlines

8.0

Very good

9,972 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

What airport do you fly into for flights to Santa Ana from Missouri?
Located just 4.8 mi from the city center, Santa Ana J. Wayne/Orange Cnty (SNA) is the airport most travelers will use when flying to Santa Ana from Missouri.
What are the cheapest airlines to fly from Missouri to Santa Ana one-way?
One-way options have recently been found by users for as low as $85 on Spirit Airlines. Other airlines that offer cheap prices include Frontier from $100 and Delta from $144 one-way.
What are the most popular routes from Missouri to Santa Ana?
The most popular flight routes from Missouri to Santa Ana are Lambert-St Louis - Santa Ana J. Wayne/Orange Cnty, Kansas City - Santa Ana J. Wayne/Orange Cnty and Springfield-Branson - Santa Ana J. Wayne/Orange Cnty.
Can I find deals for flights from Missouri to Santa Ana that include hotel bookings?
Yes. In addition to deals on Missouri to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Santa Ana?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Santa Ana.
Can I find deals for business class flights from Missouri to Santa Ana?
Yes. Cheapflights offers flight deals from Missouri to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Santa Ana?
Currently, January is the cheapest month in which you can book a flight from Missouri to Santa Ana (average of $298). Flying from Missouri to Santa Ana in June is currently the most expensive (average of $395). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Tustin

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Missouri to Santa Ana

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$130	Average$219	FlexibilityNo cancel fee	On-time65%
Frontier	Cheapest$144	Average$218	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$257	Average$376	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$268	Average$458	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$268	Average$438	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$366	Average$447	FlexibilityNo cancel fee	On-time63%

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$85+ Cheap flights from Missouri to Santa Ana (SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Missouri to Santa Ana with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Missouri to Santa Ana

Keep the following information in mind while searching for Missouri to Santa Ana flight deals. Data was last updated May 1, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Missouri to Santa Ana

Cheapest flights from Missouri to Santa AnaExplore the most affordable flight options available from Missouri to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Explore the most affordable flight options available from Missouri to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Santa Ana that are best for you.

Best time to book a flight from Missouri to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Santa Ana

What is the cheapest month to book a flight from Missouri to Santa Ana?

What is the cheapest time of day to fly from MO to SNA?

Find hourly flight availability from Missouri to Santa Ana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Rainfall in Santa Ana by month

Plan your trip to Santa Ana by taking into account the average rainfall totals by month.

Temperature in Santa Ana by month

Plan your trip to Santa Ana by taking into account the average temperature totals by month.

Reviews of airlines servicing Santa Ana

To help decide which airline to fly from Missouri to Santa Ana, see what other customers have to say about Alaska Airlines, Southwest and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santa Ana from Missouri?

What are the cheapest airlines to fly from Missouri to Santa Ana one-way?

What are the most popular routes from Missouri to Santa Ana?

Can I find deals for flights from Missouri to Santa Ana that include hotel bookings?

How can I find direct flights from Missouri to Santa Ana?

Can I find deals for business class flights from Missouri to Santa Ana?

What is the cheapest month to book a flight from Missouri to Santa Ana?

Traveling to a place near Missouri?

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Alternative routes for Missouri to Santa Ana

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Top 6 airlines flying from Missouri to Santa Ana

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Cheapest flights from Missouri to Santa Ana
Explore the most affordable flight options available from Missouri to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.