What are the cheapest airlines to fly from Missouri to Santa Ana one-way?

One-way options have recently been found by users for as low as $87 on Spirit Airlines. Other airlines that offer cheap prices include Alaska Airlines from $101 and Frontier from $108 one-way.

In terms of precipitation, rainfall in Santa Ana ranges from 0.0 - 3.1 inches per month. February is typically the wettest month, when rainfall can reach 3.1 in. July is typically the driest time to visit Santa Ana when rainfall is around 0.0 in.

If weather is an important factor for your trip to Santa Ana, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What are the most popular routes from Missouri to Santa Ana?

The most popular flight routes from Missouri to Santa Ana are Kansas City - Santa Ana J. Wayne/Orange Cnty, Lambert-St Louis - Santa Ana J. Wayne/Orange Cnty and Springfield-Branson - Santa Ana J. Wayne/Orange Cnty.

What are the most popular airlines that fly from Missouri to Santa Ana?

Before booking your flight from Missouri to Santa Ana check out the most popular airlines for this route: American Airlines, Delta or Frontier.

How far in advance should I book a flight from Missouri to Santa Ana?

Travelers have found it’s best to book a flight 55 days in advance to save up to 156% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 55 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from Missouri to Santa Ana 1-2 weeks in advance for as low as $223, or $428 for flights within the next 24 hours.

What is the cheapest month to fly from Missouri to Santa Ana?

Due to multiple factors, expect to potentially pay more when booking in March. For low rates, September can be a great choice for travel to Santa Ana. Flights to Santa Ana from Missouri in September are about $276 on average during September, but can be found for as low as $61.

What airport do you fly into for flights to Santa Ana from Missouri?

Located just 4.8 mi from the city center, Santa Ana J. Wayne/Orange Cnty (SNA) is the airport most travelers will use when flying to Santa Ana from Missouri.

Can I find deals for flights from Missouri to Santa Ana that include hotel bookings?

Yes. In addition to deals on Missouri to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Santa Ana?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Santa Ana.

Can I find deals for business class flights from Missouri to Santa Ana?

Yes. Cheapflights offers flight deals from Missouri to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$87+ Flights from Missouri to Santa Ana

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Missouri to Santa Ana with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Santa Ana

Round-trip from	$200 (Cheapflightsfares)
One-way from	$87 (Cheapflightsfares)
Popular in	March
Cheapest in	September
Average price	$260

From Missouri to Santa Ana J. Wayne/Orange Cnty

Search Deals

One-way flight from Missouri to Santa Ana J. Wayne/Orange Cnty

Search Deals

Highest demand for flights based on searches. 25% potential increase in price ($91 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($12 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in July 2025

Search Deals

Find flight deals from Missouri to Santa Ana

Cheapest flights from Missouri to Santa Ana
Explore the most affordable flight options available from Missouri to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2025.

Wed 11/57:00 amMCI - SNA

1 stop11h 51mSpirit Airlines

Sat 11/85:46 pmSNA - MCI

1 stop4h 54mSpirit Airlines

Deal found 7/26

$155

Sat 8/167:29 pmSTL - SNA

1 stop17h 41mFrontier

Sat 8/2312:04 pmSNA - STL

1 stop19h 07mFrontier

Deal found 7/26

$218

Sun 8/312:30 pmSTL - SNA

1 stop22h 59mSpirit Airlines

Wed 9/312:24 pmSNA - STL

1 stop20h 26mSpirit Airlines

Deal found 7/27

$229

Mon 8/118:01 pmMCI - SNA

1 stop17h 10mFrontier

Fri 8/1512:01 pmSNA - MCI

1 stop5h 03mFrontier

Deal found 7/27

$247

Thu 8/285:15 amSTL - SNA

1 stop7h 18mAmerican Airlines

Mon 9/14:30 pmSNA - STL

1 stop5h 46mAmerican Airlines

Deal found 7/27

$267

Fri 8/2210:04 amSGF - SNA

1 stop5h 41mAmerican Airlines

Sat 8/3010:10 amSNA - SGF

1 stop6h 53mAmerican Airlines

Deal found 7/27

$269

Tue 9/304:50 pmSTL - SNA

1 stop5h 39mUnited Airlines

Tue 10/711:32 amSNA - STL

2 stops9h 03mUnited Airlines

Deal found 7/27

$272

Thu 8/286:45 pmSTL - SNA

1 stop5h 38mDelta

Thu 9/49:20 pmSNA - STL

1 stop9h 55mDelta

Deal found 7/27

$277

Mon 9/154:40 pmSTL - SNA

1 stop7h 30mSouthwest

Thu 9/186:45 amSNA - STL

2 stops9h 50mSouthwest

Deal found 7/27

$282

Wed 9/104:55 pmMCI - SNA

1 stop7h 22mHawaiian Airlines

Tue 9/167:00 amSNA - MCI

1 stop7h 01mHawaiian Airlines

Deal found 7/27

$286

Wed 8/202:30 pmMCI - SNA

1 stop5h 52mDelta

Tue 8/269:39 amSNA - MCI

1 stop5h 25mDelta

Deal found 7/27

$287

Wed 11/59:45 amMCI - SNA

1 stop6h 28mAmerican Airlines

Sat 11/81:27 pmSNA - MCI

2 stops7h 40mAmerican Airlines

Deal found 7/26

$292

Best flights from Missouri to Santa Ana
Discover carefully curated flight deals from Missouri to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2025.

Fri 10/176:01 pmMCI - SNA

1 stop6h 04mSpirit Airlines

Tue 10/216:45 amSNA - MCI

1 stop5h 15mSpirit Airlines

Deal found 7/26

$200

Thu 11/67:52 pmSTL - SNA

1 stop17h 24mFrontier

Tue 11/1112:01 pmSNA - STL

1 stop19h 06mFrontier

Deal found 7/27

$235

Thu 8/285:15 amSTL - SNA

1 stop7h 18mAmerican Airlines

Mon 9/14:30 pmSNA - STL

1 stop5h 46mAmerican Airlines

Deal found 7/27

$267

Tue 9/304:50 pmSTL - SNA

1 stop5h 39mUnited Airlines

Tue 10/711:32 amSNA - STL

2 stops9h 03mUnited Airlines

Deal found 7/27

$272

Thu 8/286:45 pmSTL - SNA

1 stop5h 38mDelta

Wed 9/312:03 pmSNA - STL

1 stop7h 59mDelta

Deal found 7/27

$277

Mon 9/154:40 pmSTL - SNA

1 stop7h 30mSouthwest

Thu 9/186:45 amSNA - STL

2 stops9h 50mSouthwest

Deal found 7/27

$282

Wed 9/104:55 pmMCI - SNA

1 stop7h 22mHawaiian Airlines

Tue 9/167:00 amSNA - MCI

1 stop7h 01mHawaiian Airlines

Deal found 7/27

$286

Thu 9/116:00 amSTL - SNA

1 stop10h 17mAlaska Airlines

Thu 9/186:45 amSNA - STL

1 stop8h 49mAlaska Airlines

Deal found 7/28

$318

Tue 9/309:50 amSTL - SNA

3 stops14h 15mMultiple Airlines

Tue 10/76:45 amSNA - STL

3 stops27h 15mMultiple Airlines

Deal found 7/27

$404

Sun 8/312:30 pmSTL - SNA

1 stop22h 59mSpirit Airlines

Wed 9/312:24 pmSNA - STL

1 stop20h 26mSpirit Airlines

Deal found 7/27

$229

Mon 8/118:01 pmMCI - SNA

1 stop17h 10mFrontier

Fri 8/1512:01 pmSNA - MCI

1 stop5h 03mFrontier

Deal found 7/27

$247

Fri 8/2210:04 amSGF - SNA

1 stop5h 41mAmerican Airlines

Sat 8/3010:10 amSNA - SGF

1 stop6h 53mAmerican Airlines

Deal found 7/27

$269

Last-minute flights from Missouri to Santa Ana
Discover last-minute flight deals from Missouri to Santa Ana. Data last updated July 28, 2025 and is based on user searches.

Sat 8/23:06 pmMCI - SNA

1 stop8h 54mUnited Airlines

Tue 8/126:50 amSNA - MCI

1 stop7h 20mUnited Airlines

Deal found 7/27

$643

Sat 8/27:44 amSTL - SNA

1 stop6h 04mAmerican Airlines

Wed 8/68:15 amSNA - STL

1 stop6h 32mAmerican Airlines

Deal found 7/27

$761

Sat 8/26:33 amSTL - SNA

1 stop7h 05mUnited Airlines

Wed 8/68:51 amSNA - STL

2 stops11h 54mUnited Airlines

Deal found 7/28

$766

Sun 8/37:59 pmMCI - SNA

2 stops24h 38mMultiple Airlines

Sat 8/94:52 pmSNA - MCI

2 stops20h 25mMultiple Airlines

Deal found 7/27

$537

Tue 8/56:04 pmMCI - SNA

1 stop5h 42mDelta

Sun 8/105:05 pmSNA - MCI

1 stop5h 16mDelta

Deal found 7/27

$603

Tue 8/53:34 pmMCI - SNA

1 stop8h 56mAlaska Airlines

Thu 8/76:45 amSNA - MCI

1 stop10h 16mAlaska Airlines

Deal found 7/27

$737

Thu 8/76:00 amMCI - SNA

2 stops17h 21mSpirit Airlines

Mon 8/117:58 pmSNA - MCI

1 stop15h 39mSpirit Airlines

Deal found 7/26

$342

Mon 8/112:37 pmSTL - SNA

1 stop6h 03mFrontier

Mon 8/1812:01 pmSNA - STL

1 stop19h 10mFrontier

Deal found 7/27

$245

Mon 8/118:01 pmMCI - SNA

1 stop17h 10mFrontier

Fri 8/1512:01 pmSNA - MCI

1 stop5h 03mFrontier

Deal found 7/27

$247

Wed 8/202:30 pmMCI - SNA

1 stop5h 52mDelta

Tue 8/269:39 amSNA - MCI

1 stop5h 25mDelta

Deal found 7/27

$287

Fri 8/2210:04 amSGF - SNA

1 stop5h 41mAmerican Airlines

Sat 8/3010:10 amSNA - SGF

1 stop6h 53mAmerican Airlines

Deal found 7/27

$269

Fri 8/223:54 pmSGF - SNA

1 stop8h 18mDelta

Sat 8/308:00 amSNA - SGF

2 stops12h 05mDelta

Deal found 7/27

$299

One-way flights from Missouri to Santa Ana
Search for one-way flight options from Missouri to Santa Ana. Find affordable one-way fares based on user searches. Data last updated July 28, 2025.

Thu 10/236:01 pmMCI - SNA

1 stop6h 04mSpirit Airlines

Deal found 7/27

$87

Tue 8/263:37 pmMCI - SNA

1 stop8h 05mAlaska Airlines

Deal found 7/26

$101

Fri 10/102:19 pmSTL - SNA

1 stop5h 55mFrontier

Deal found 7/27

$108

Thu 9/1812:05 pmSTL - SNA

1 stop25h 30mSpirit Airlines

Deal found 7/26

$120

Sat 10/256:33 amSTL - SNA

1 stop9h 44mAlaska Airlines

Deal found 7/26

$130

Sat 10/257:30 amMCI - SNA

2 stops9h 41mUnited Airlines

Deal found 7/27

$149

Sat 8/165:30 pmSTL - SNA

1 stop6h 53mDelta

Deal found 7/27

$246

Wed 8/138:15 amSTL - SNA

2 stops9h 25mSouthwest

Deal found 7/26

$251

Sat 8/165:00 amSTL - SNA

2 stops10h 00mUnited Airlines

Deal found 7/27

$296

Sat 8/210:08 amSTL - SNA

2 stops9h 49mAmerican Airlines

Deal found 7/26

$386

Fly from

Fly to

Route

Depart

Return

Price

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Fri 10/17

6:01 pm-10:05 pm

1 stop6h 04m

Santa Ana J. Wayne/Orange Cnty

Tue 10/21

6:45 am-2:00 pm

1 stop5h 15m

$200

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Sat 8/16

7:29 pm-11:10 am

1 stop17h 41m

Santa Ana J. Wayne/Orange Cnty

Sat 8/23

12:04 pm-9:11 am

1 stop19h 07m

$218

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Sun 8/31

2:30 pm-11:29 am

1 stop22h 59m

Santa Ana J. Wayne/Orange Cnty

Wed 9/3

12:24 pm-10:50 am

1 stop20h 26m

$229

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Mon 8/11

8:01 pm-11:11 am

1 stop17h 10m

Santa Ana J. Wayne/Orange Cnty

Fri 8/15

12:01 pm-7:04 pm

1 stop5h 03m

$247

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 8/28

5:15 am-10:33 am

1 stop7h 18m

Santa Ana J. Wayne/Orange Cnty

Mon 9/1

4:30 pm-12:16 am

1 stop5h 46m

$267

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Fri 8/22

10:04 am-1:45 pm

1 stop5h 41m

Santa Ana J. Wayne/Orange Cnty

Sat 8/30

10:10 am-7:03 pm

1 stop6h 53m

$269

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Tue 9/30

4:50 pm-8:29 pm

1 stop5h 39m

Santa Ana J. Wayne/Orange Cnty

Tue 10/7

11:32 am-10:35 pm

2 stops9h 03m

$272

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 8/28

6:45 pm-10:23 pm

1 stop5h 38m

Santa Ana J. Wayne/Orange Cnty

Thu 9/4

9:20 pm-9:15 am

1 stop9h 55m

$277

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Mon 9/15

4:40 pm-10:10 pm

1 stop7h 30m

Santa Ana J. Wayne/Orange Cnty

Thu 9/18

6:45 am-6:35 pm

2 stops9h 50m

$282

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Wed 9/10

4:55 pm-10:17 pm

1 stop7h 22m

Santa Ana J. Wayne/Orange Cnty

Tue 9/16

7:00 am-4:01 pm

1 stop7h 01m

$286

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Showing 1-10 of 34 results

Best time to book a flight from Missouri to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Santa Ana

What is the cheapest month to book a flight from Missouri to Santa Ana?

Currently, January is the cheapest month in which you can book a flight from Missouri to Santa Ana (average of $298). Flying from Missouri to Santa Ana in March is currently the most expensive (average of $377). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SNA?

When flying from Missouri to Santa Ana, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Santa Ana

Read reviews from past customers who have flown Alaska Airlines, Southwest, and Delta from Missouri to Santa Ana. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

8.0

Very good

10,000 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Alaska Airlines

8.0

Very good

10,000 reviews

Alaska Airlines

8.0

Very good

10,000 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Southwest

8.0

Very good

4,238 reviews

Alaska Airlines

8.0

Very good

10,000 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Delta

8.0

Very good

7,975 reviews

Alaska Airlines

8.0

Very good

10,000 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Hawaiian Airlines

7.8

Good

2,604 reviews

Alaska Airlines

8.0

Very good

10,000 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

United Airlines

7.4

Good

8,892 reviews

Alaska Airlines

8.0

Very good

10,000 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

What airport do you fly into for flights to Santa Ana from Missouri?
Located just 4.8 mi from the city center, Santa Ana J. Wayne/Orange Cnty (SNA) is the airport most travelers will use when flying to Santa Ana from Missouri.
What are the cheapest airlines to fly from Missouri to Santa Ana one-way?
One-way options have recently been found by users for as low as $87 on Spirit Airlines. Other airlines that offer cheap prices include Alaska Airlines from $101 and Frontier from $108 one-way.
What are the most popular routes from Missouri to Santa Ana?
The most popular flight routes from Missouri to Santa Ana are Kansas City - Santa Ana J. Wayne/Orange Cnty, Lambert-St Louis - Santa Ana J. Wayne/Orange Cnty and Springfield-Branson - Santa Ana J. Wayne/Orange Cnty.
Can I find deals for flights from Missouri to Santa Ana that include hotel bookings?
Yes. In addition to deals on Missouri to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Santa Ana?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Santa Ana.
Can I find deals for business class flights from Missouri to Santa Ana?
Yes. Cheapflights offers flight deals from Missouri to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Santa Ana?
Currently, January is the cheapest month in which you can book a flight from Missouri to Santa Ana (average of $298). Flying from Missouri to Santa Ana in March is currently the most expensive (average of $377). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Tustin

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Missouri to Santa Ana

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$88	Average$197	FlexibilityNo cancel fee	On-time65%
Frontier	Cheapest$144	Average$218	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$241	Average$396	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$268	Average$446	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$268	Average$425	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$331	Average$447	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$87+ Cheap flights from Missouri to Santa Ana (SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Missouri to Santa Ana with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Missouri to Santa Ana

Keep the following information in mind while searching for Missouri to Santa Ana flight deals. Data was last updated July 28, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Missouri to Santa Ana

Cheapest flights from Missouri to Santa AnaExplore the most affordable flight options available from Missouri to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2025.

Explore the most affordable flight options available from Missouri to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Santa Ana that are best for you.

Best time to book a flight from Missouri to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Santa Ana

What is the cheapest month to book a flight from Missouri to Santa Ana?

What is the cheapest time of day to fly from MO to SNA?

Find hourly flight availability from Missouri to Santa Ana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 28, 2025.

Reviews of airlines servicing Santa Ana

Read reviews from past customers who have flown Alaska Airlines, Southwest, and Delta from Missouri to Santa Ana. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santa Ana from Missouri?

What are the cheapest airlines to fly from Missouri to Santa Ana one-way?

What are the most popular routes from Missouri to Santa Ana?

Can I find deals for flights from Missouri to Santa Ana that include hotel bookings?

How can I find direct flights from Missouri to Santa Ana?

Can I find deals for business class flights from Missouri to Santa Ana?

What is the cheapest month to book a flight from Missouri to Santa Ana?

Traveling to a place near Santa Ana?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Santa Ana

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Missouri to Santa Ana

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Missouri to Santa Ana
Explore the most affordable flight options available from Missouri to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2025.