How long is the flight from Missouri to Santa Ana, California?

Airlines like Spirit Airlines, Frontier, and United Airlines fly from Missouri to Santa Ana, California in about 9h 20m. The time it takes to get you to your destination can typically vary by up to 12h 26m. The distance between Missouri and Santa Ana, California is about 1466 mi. Both multi-stop and nonstop flights can be found to your destination and back.

In terms of precipitation, rainfall in Santa Ana, California ranges from 0.0 - 3.1 inches per month. February is typically the wettest month, when rainfall can reach 3.1 in. July is typically the driest time to visit Santa Ana, California when rainfall is around 0.0 in.

If weather is an important factor for your trip to Santa Ana, California, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What are the most popular routes from Missouri to Santa Ana, California?

The most popular flight routes from Missouri to Santa Ana, California are Kansas City - Santa Ana J. Wayne/Orange Cnty, Lambert-St Louis - Santa Ana J. Wayne/Orange Cnty and Springfield-Branson - Santa Ana J. Wayne/Orange Cnty.

What airport do you fly into for flights to Santa Ana from Missouri?

Located just 4.8 mi from the city center, Santa Ana J. Wayne/Orange Cnty (SNA) is the airport most travelers will use when flying to Santa Ana from Missouri.

Can I find deals for flights from Missouri to Santa Ana that include hotel bookings?

Yes. In addition to deals on Missouri to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Santa Ana?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Santa Ana.

Can I find deals for business class flights from Missouri to Santa Ana?

Yes. Cheapflights offers flight deals from Missouri to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$55+ Flights from Missouri to Santa Ana, CA

Q: How much does it cost to fly round-trip from Missouri to Santa Ana, California?

Airfare is below average for this route at the moment. Missouri to Santa Ana, California flights typically cost between $331 and $478 in January. The cheapest round-trip price found within the last 3 days was $149 on Spirit Airlines (Jan 13-Jan 20).

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Missouri to Santa Ana with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Santa Ana

Cheapest flights from Missouri to Santa Ana
Explore the most affordable flight options available from Missouri to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Sun 12/2110:10 pmSTL - SNA

1 stop23h 11mFrontier

Mon 12/298:16 pmSNA - STL

1 stop23h 09mFrontier

Deal found 12/16

$289

Sat 12/2010:10 pmSTL - SNA

1 stop23h 02mFrontier

Mon 12/228:16 pmSNA - STL

1 stop23h 09mFrontier

Deal found 12/16

$325

Sat 12/2010:10 pmSTL - SNA

1 stop23h 02mFrontier

Sun 12/287:57 pmSNA - STL

1 stop23h 28mFrontier

Deal found 12/16

$329

Wed 12/245:45 amMCI - SNA

1 stop5h 53mUnited Airlines

Thu 1/17:04 amSNA - MCI

1 stop6h 05mUnited Airlines

Deal found 12/16

$335

Tue 12/237:00 amMCI - SNA

1 stop5h 16mSpirit Airlines

Wed 1/76:45 amSNA - MCI

1 stop6h 07mSpirit Airlines

Deal found 12/16

$338

Wed 12/317:43 pmSTL - SNA

1 stop18h 52mFrontier

Sun 1/47:57 pmSNA - STL

1 stop23h 28mFrontier

Deal found 12/16

$338

Sun 12/2110:10 pmSTL - SNA

1 stop23h 11mFrontier

Sun 12/287:57 pmSNA - STL

1 stop23h 28mFrontier

Deal found 12/16

$343

Wed 12/242:04 pmSTL - SNA

1 stop8h 47mAmerican Airlines

Thu 1/16:45 amSNA - STL

1 stop5h 13mAmerican Airlines

Deal found 12/17

$356

Wed 12/247:43 pmSTL - SNA

1 stop18h 52mFrontier

Thu 1/111:52 amSNA - STL

1 stop20h 10mFrontier

Deal found 12/16

$364

Fri 12/1910:10 pmSTL - SNA

1 stop22h 00mFrontier

Sun 12/2111:52 amSNA - STL

1 stop20h 10mFrontier

Deal found 12/15

$368

Wed 12/245:45 amMCI - SNA

1 stop5h 53mUnited Airlines

Wed 12/317:05 pmSNA - MCI

2 stops13h 38mUnited Airlines

Deal found 12/16

$380

Thu 12/2511:53 amMCI - SNA

1 stop22h 34mMultiple Airlines

Sun 12/287:57 pmSNA - MCI

1 stop16h 55mMultiple Airlines

Deal found 12/17

$392

Best flights from Missouri to Santa Ana
Discover carefully curated flight deals from Missouri to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Tue 1/137:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Tue 1/201:20 pmSNA - MCI

1 stop8h 13mSpirit Airlines

Deal found 12/16

$149

Sat 1/243:46 pmSTL - SNA

1 stop21h 46mMultiple Airlines

Thu 1/296:45 amSNA - STL

1 stop12h 21mMultiple Airlines

Deal found 12/16

$156

Sat 2/212:51 pmSTL - SNA

1 stop21h 46mFrontier

Mon 3/212:36 pmSNA - STL

1 stop5h 16mFrontier

Deal found 12/15

$185

Fri 1/232:53 pmMCI - SNA

1 stop5h 32mDelta

Sun 1/2511:15 amSNA - MCI

1 stop10h 24mDelta

Deal found 12/16

$237

Wed 2/183:10 pmCOU - SNA

1 stop9h 20mUnited Airlines

Sat 2/281:20 pmSNA - COU

1 stop5h 20mUnited Airlines

Deal found 12/16

$278

Wed 1/76:34 pmSGF - SNA

1 stop6h 22mAmerican Airlines

Wed 1/143:15 pmSNA - SGF

1 stop5h 32mAmerican Airlines

Deal found 12/16

$289

Wed 1/147:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Wed 1/211:20 pmSNA - MCI

1 stop8h 13mSpirit Airlines

Deal found 12/16

$163

Thu 1/87:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Wed 2/114:37 pmSNA - MCI

1 stop4h 56mSpirit Airlines

Deal found 12/17

$179

Mon 2/21:40 pmSTL - SNA

2 stops24h 45mMultiple Airlines

Fri 2/66:45 amSNA - STL

1 stop12h 03mMultiple Airlines

Deal found 12/15

$204

Mon 1/127:00 amMCI - SNA

1 stop7h 25mSpirit Airlines

Fri 1/164:37 pmSNA - MCI

1 stop4h 56mSpirit Airlines

Deal found 12/17

$188

Wed 1/212:53 pmMCI - SNA

1 stop5h 32mDelta

Sun 1/2511:15 amSNA - MCI

1 stop10h 24mDelta

Deal found 12/16

$237

Sat 1/244:04 pmMCI - SNA

1 stop6h 28mDelta

Thu 1/2911:15 amSNA - MCI

1 stop10h 08mDelta

Deal found 12/16

$237

Thu 1/87:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Sun 1/111:20 pmSNA - MCI

1 stop8h 13mSpirit Airlines

Deal found 12/16

$197

Thu 1/15:19 pmSTL - SNA

1 stop27h 03mFrontier

Fri 1/91:31 pmSNA - STL

1 stop5h 50mFrontier

Deal found 12/15

$269

Fri 1/96:34 pmSGF - SNA

1 stop6h 22mAmerican Airlines

Wed 1/1411:42 amSNA - SGF

1 stop6h 43mAmerican Airlines

Deal found 12/15

$289

Fri 2/67:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Tue 2/101:20 pmSNA - MCI

1 stop8h 13mSpirit Airlines

Deal found 12/15

$209

Tue 3/33:49 pmSTL - SNA

2 stops25h 53mMultiple Airlines

Fri 3/611:32 amSNA - STL

1 stop20h 17mMultiple Airlines

Deal found 12/15

$300

Sat 1/313:31 pmSTL - SNA

2 stops20h 48mDelta

Sat 2/77:30 amSNA - STL

2 stops13h 55mDelta

Deal found 12/17

$276

Wed 2/187:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Sun 2/224:37 pmSNA - MCI

1 stop4h 56mSpirit Airlines

Deal found 12/17

$216

Sat 1/1011:17 amCOU - SNA

1 stop9h 24mUnited Airlines

Tue 1/1310:51 amSNA - COU

1 stop8h 46mUnited Airlines

Deal found 12/14

$358

Tue 3/33:49 pmSTL - SNA

2 stops25h 53mMultiple Airlines

Sat 3/74:37 pmSNA - STL

1 stop24h 50mMultiple Airlines

Deal found 12/15

$306

Fri 1/306:10 amSTL - SNA

2 stops18h 08mDelta

Fri 2/67:30 amSNA - STL

2 stops13h 53mDelta

Deal found 12/17

$297

Fri 1/95:03 pmSGF - SNA

1 stop6h 15mUnited Airlines

Wed 1/1412:23 pmSNA - SGF

1 stop7h 21mUnited Airlines

Deal found 12/15

$369

Fri 1/306:10 amSTL - SNA

2 stops18h 08mDelta

Sat 2/77:30 amSNA - STL

2 stops12h 08mDelta

Deal found 12/17

$297

Sat 1/319:00 amSGF - SNA

1 stop8h 10mUnited Airlines

Wed 2/49:00 amSNA - SGF

1 stop5h 22mUnited Airlines

Deal found 12/15

$369

Fri 1/306:10 amSTL - SNA

2 stops18h 08mDelta

Wed 2/411:15 amSNA - STL

2 stops10h 10mDelta

Deal found 12/17

$297

Wed 1/71:28 pmSGF - SNA

1 stop6h 00mUnited Airlines

Wed 1/1411:05 amSNA - SGF

2 stops8h 53mUnited Airlines

Deal found 12/16

$374

Tue 3/37:00 amSTL - SNA

2 stops11h 14mDelta

Fri 3/611:15 amSNA - STL

2 stops10h 08mDelta

Deal found 12/15

$316

Tue 2/38:45 amCOU - SNA

1 stop8h 25mUnited Airlines

Mon 2/911:05 amSNA - COU

1 stop7h 28mUnited Airlines

Deal found 12/16

$383

Tue 4/286:28 pmJLN - SNA

1 stop5h 34mUnited Airlines

Sat 5/211:08 amSNA - JLN

2 stops10h 43mUnited Airlines

Deal found 12/15

$434

Last-minute flights from Missouri to Santa Ana
Discover last-minute flight deals from Missouri to Santa Ana. Data last updated December 18, 2025 and is based on user searches.

Wed 1/77:43 pmSTL - SNA

1 stop17h 09mFrontier

Tue 1/133:55 pmSNA - STL

1 stop20h 53mFrontier

Deal found 12/16

$183

Thu 1/87:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Wed 2/114:37 pmSNA - MCI

1 stop4h 56mSpirit Airlines

Deal found 12/17

$179

Thu 1/87:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Sun 1/111:20 pmSNA - MCI

1 stop8h 13mSpirit Airlines

Deal found 12/17

$191

Fri 1/97:00 amMCI - SNA

1 stop7h 25mSpirit Airlines

Mon 1/121:20 pmSNA - MCI

1 stop8h 13mSpirit Airlines

Deal found 12/17

$188

Tue 1/137:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Tue 1/201:20 pmSNA - MCI

1 stop8h 13mSpirit Airlines

Deal found 12/16

$149

Wed 1/147:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Wed 1/211:20 pmSNA - MCI

1 stop8h 13mSpirit Airlines

Deal found 12/16

$163

Fri 1/168:27 pmMCI - SNA

1 stop20h 33mMultiple Airlines

Mon 1/195:31 pmSNA - MCI

1 stop28h 02mMultiple Airlines

Deal found 12/17

$178

Sat 1/243:46 pmSTL - SNA

1 stop21h 46mMultiple Airlines

Thu 1/296:45 amSNA - STL

1 stop12h 21mMultiple Airlines

Deal found 12/16

$156

Fri 1/307:00 amMCI - SNA

1 stop7h 25mMultiple Airlines

Mon 2/211:33 amSNA - MCI

1 stop6h 18mMultiple Airlines

Deal found 12/16

$185

Fri 1/307:39 pmSTL - SNA

2 stops27h 18mMultiple Airlines

Fri 2/66:45 amSNA - STL

1 stop12h 03mMultiple Airlines

Deal found 12/17

$191

Sat 1/313:46 pmSTL - SNA

1 stop21h 46mMultiple Airlines

Fri 2/66:45 amSNA - STL

1 stop12h 03mMultiple Airlines

Deal found 12/17

$158

Sat 1/313:46 pmSTL - SNA

1 stop21h 46mFrontier

Sun 2/812:17 pmSNA - STL

1 stop22h 33mFrontier

Deal found 12/17

$175

One-way flights from Missouri to Santa Ana
Search for one-way flight options from Missouri to Santa Ana. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Tue 1/207:00 amMCI - SNA

1 stop7h 25mSpirit Airlines

Deal found 12/17

$55

Tue 2/247:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Deal found 12/15

$61

Fri 1/167:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Deal found 12/17

$76

Wed 4/297:00 amMCI - SNA

1 stop7h 25mSpirit Airlines

Deal found 12/16

$78

Wed 1/77:43 pmSTL - SNA

1 stop17h 09mFrontier

Deal found 12/17

$81

Tue 1/277:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Deal found 12/17

$82

Wed 2/187:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Deal found 12/17

$83

Tue 2/107:00 amMCI - SNA

1 stop7h 25mSpirit Airlines

Deal found 12/17

$85

Wed 2/257:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Deal found 12/17

$88

Wed 5/67:00 amMCI - SNA

1 stop7h 25mSpirit Airlines

Deal found 12/18

$89

Tue 4/287:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Deal found 12/17

$90

Mon 1/267:00 amMCI - SNA

1 stop10h 42mSpirit Airlines

Deal found 12/18

$93

Find flight deals from Missouri to Santa Ana

Most accurate provider	Justfly.com 3 stars
Most trusted provider	Justfly.com 3 stars
Round-trip from	$149 (CheapOair)
One-way from	$55 (CheapOair)
Popular in	March
Cheapest in	September
Average price	$416

Provider with most accurate pricing for Lambert-St Louis-Los Angeles flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-Los Angeles flights.

Search Deals

From Missouri to Santa Ana J. Wayne/Orange Cnty

Search Deals

One-way flight from Missouri to Santa Ana J. Wayne/Orange Cnty

Search Deals

Highest demand for flights based on searches. 3% potential increase in price ($15 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Tue 1/13

7:00 am-3:42 pm

1 stop10h 42m

Santa Ana J. Wayne/Orange Cnty

Tue 1/20

1:20 pm-11:33 pm

1 stop8h 13m

$149

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Sat 1/24

3:46 pm-11:32 am

1 stop21h 46m

Santa Ana J. Wayne/Orange Cnty

Thu 1/29

6:45 am-9:06 pm

1 stop12h 21m

$156

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Wed 1/14

7:00 am-3:42 pm

1 stop10h 42m

Santa Ana J. Wayne/Orange Cnty

Wed 1/21

1:20 pm-11:33 pm

1 stop8h 13m

$163

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Thu 1/8

7:00 am-3:42 pm

1 stop10h 42m

Santa Ana J. Wayne/Orange Cnty

Wed 2/11

4:37 pm-11:33 pm

1 stop4h 56m

$179

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Sat 2/21

2:51 pm-10:37 am

1 stop21h 46m

Santa Ana J. Wayne/Orange Cnty

Mon 3/2

12:36 pm-7:52 pm

1 stop5h 16m

$185

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Mon 1/12

7:00 am-12:25 pm

1 stop7h 25m

Santa Ana J. Wayne/Orange Cnty

Fri 1/16

4:37 pm-11:33 pm

1 stop4h 56m

$188

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Thu 1/8

7:00 am-3:42 pm

1 stop10h 42m

Santa Ana J. Wayne/Orange Cnty

Sun 1/11

1:20 pm-11:33 pm

1 stop8h 13m

$197

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Mon 2/2

1:40 pm-12:25 pm

2 stops24h 45m

Santa Ana J. Wayne/Orange Cnty

Fri 2/6

6:45 am-8:48 pm

1 stop12h 03m

$204

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Fri 2/6

7:00 am-3:42 pm

1 stop10h 42m

Santa Ana J. Wayne/Orange Cnty

Tue 2/10

1:20 pm-11:33 pm

1 stop8h 13m

$209

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Wed 2/18

7:00 am-3:42 pm

1 stop10h 42m

Santa Ana J. Wayne/Orange Cnty

Sun 2/22

4:37 pm-11:33 pm

1 stop4h 56m

$216

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 54 results

...

Best time to book a flight from Missouri to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Santa Ana

What is the cheapest month to book a flight from Missouri to Santa Ana, California?

Currently, November is the cheapest month in which you can book a flight from Missouri to Santa Ana, California (average of $67). Flying from Missouri to Santa Ana, California in December is currently the most expensive (average of $123). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SNA?

One of the essential ways to save on airfare from Missouri to Santa Ana, California is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 61% on airfare.

What is the cheapest day to fly from Missouri to Santa Ana, California?

Travelers seeking maximum savings on their Missouri to Santa Ana, California flight should consider departing on Friday evenings when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Missouri to Santa Ana, California?

Related info for your journey

What airport do you fly into for flights to Santa Ana from Missouri?
Located just 4.8 mi from the city center, Santa Ana J. Wayne/Orange Cnty (SNA) is the airport most travelers will use when flying to Santa Ana from Missouri.
How long is the flight from Missouri to Santa Ana, California?
Airlines like Spirit Airlines, Frontier, and United Airlines fly from Missouri to Santa Ana, California in about 9h 20m. The time it takes to get you to your destination can typically vary by up to 12h 26m. The distance between Missouri and Santa Ana, California is about 1466 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the most popular routes from Missouri to Santa Ana, California?
The most popular flight routes from Missouri to Santa Ana, California are Kansas City - Santa Ana J. Wayne/Orange Cnty, Lambert-St Louis - Santa Ana J. Wayne/Orange Cnty and Springfield-Branson - Santa Ana J. Wayne/Orange Cnty.
Can I find deals for flights from Missouri to Santa Ana that include hotel bookings?
Yes. In addition to deals on Missouri to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Santa Ana?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Santa Ana.
Can I find deals for business class flights from Missouri to Santa Ana?
Yes. Cheapflights offers flight deals from Missouri to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Santa Ana, California?
Currently, November is the cheapest month in which you can book a flight from Missouri to Santa Ana, California (average of $67). Flying from Missouri to Santa Ana, California in December is currently the most expensive (average of $123). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Tustin

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Missouri to Santa Ana

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$88	Average$197	FlexibilityNo cancel fee	On-time65%
Frontier	Cheapest$126	Average$168	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$203	Average$395	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$264	Average$412	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$268	Average$451	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$310	Average$450	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$55+ Cheap flights from Missouri to Santa Ana, CA (SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Missouri to Santa Ana with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Missouri to Santa Ana

Cheapest flights from Missouri to Santa AnaExplore the most affordable flight options available from Missouri to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from Missouri to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from Missouri to Santa Ana

Keep the following information in mind while searching for Missouri to Santa Ana flight deals. Data was last updated December 18, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Santa Ana that are best for you.

Best time to book a flight from Missouri to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Santa Ana

What is the cheapest month to book a flight from Missouri to Santa Ana, California?

What is the cheapest time of day to fly from MO to SNA?

Find hourly flight availability from Missouri to Santa Ana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

What is the cheapest day to fly from Missouri to Santa Ana, California?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Santa Ana. Price data was last updated on December 16, 2024.

How much does it cost to fly round-trip from Missouri to Santa Ana, California?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santa Ana from Missouri?

How long is the flight from Missouri to Santa Ana, California?

What are the most popular routes from Missouri to Santa Ana, California?

Can I find deals for flights from Missouri to Santa Ana that include hotel bookings?

How can I find direct flights from Missouri to Santa Ana?

Can I find deals for business class flights from Missouri to Santa Ana?

What is the cheapest month to book a flight from Missouri to Santa Ana, California?

Traveling to a place near Santa Ana?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Santa Ana

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Missouri to Santa Ana

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Missouri to Santa Ana
Explore the most affordable flight options available from Missouri to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.