Santa Ana

$132+ Cheap flights from O'Hare Intl (ORD) to Santa Ana, CA (SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — SNA
Dec 4 — Dec 111
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Chicago O'Hare Intl to Santa Ana J. Wayne/Orange Cnty are usually found in August or January, booked 85 days in advance, depart on a Saturday or Wednesday and return on a Wednesday

Find flight deals from O'Hare Intl to Santa Ana

Cheapest flights from O'Hare Intl to Santa Ana
Explore the most affordable flight options available from O'Hare Intl to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2025.

This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:14 amORD - SNA
Nonstop4h 37mAmerican Airlines
Mon 12/83:04 pmSNA - ORD
Nonstop4h 20mAmerican Airlines
Deal found 11/3$269
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/199:22 pmORD - SNA
2 stops26h 51mSpirit Airlines
Mon 12/811:39 amSNA - ORD
2 stops30h 22mSpirit Airlines
Deal found 11/3$270
This Trip.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:00 amORD - SNA
1 stop7h 16mFrontier
Sun 11/2310:07 amSNA - ORD
1 stop8h 21mFrontier
Deal found 11/2$271
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:45 pmORD - SNA
1 stop23h 14mFrontier
Fri 11/2812:04 pmSNA - ORD
1 stop10h 06mFrontier
Deal found 11/4$272
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/208:18 pmORD - SNA
2 stops24h 28mSpirit Airlines
Mon 12/88:19 pmSNA - ORD
2 stops12h 49mSpirit Airlines
Deal found 11/3$273
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:05 pmORD - SNA
2 stops24h 46mMultiple Airlines
Sun 11/2312:04 pmSNA - ORD
1 stop10h 06mMultiple Airlines
Deal found 11/2$274
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:50 amORD - SNA
1 stop12h 20mDelta
Tue 12/97:15 amSNA - ORD
1 stop14h 44mDelta
Deal found 11/4$275
This Alaska Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:05 pmORD - SNA
1 stop10h 21mAlaska Airlines
Sat 12/66:45 amSNA - ORD
1 stop8h 10mAlaska Airlines
Deal found 11/3$277
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:55 amORD - SNA
1 stop7h 22mUnited Airlines
Sat 12/62:15 pmSNA - ORD
Nonstop4h 05mUnited Airlines
Deal found 11/3$279
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:30 amORD - SNA
2 stops14h 18mMultiple Airlines
Mon 11/176:45 amSNA - ORD
1 stop13h 03mMultiple Airlines
Deal found 11/3$280
This Frontier deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/207:00 amORD - SNA
1 stop6h 19mFrontier
Tue 11/2510:07 amSNA - ORD
1 stop8h 21mFrontier
Deal found 11/3$281
This Frontier deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:00 amORD - SNA
1 stop7h 16mFrontier
Sat 11/82:20 pmSNA - ORD
1 stop7h 09mFrontier
Deal found 11/3$282

Cheap flight deals from O'Hare Intl to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$269
(American Airlines)

One-way from

$132
(Mytrip)

Popular in

December

Cheapest in

August

Average price

$384

Good round-trip deal

$297 or less

Good one-way deal

$266 or less
Provider with most accurate pricing for Chicago O'Hare Intl-Santa Ana J. Wayne/Orange Cnty flight deals.
Provider most trusted by Cheapflights users for Chicago O'Hare Intl-Santa Ana J. Wayne/Orange Cnty flights.
From Chicago O'Hare Intl to Santa Ana J. Wayne/Orange Cnty
One-way flight from Chicago O'Hare Intl to Santa Ana J. Wayne/Orange Cnty
Highest demand for flights based on searches. 2% potential increase in price ($9 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Average for round-trip flights in November 2025
Price to beat on a round-trip flight from Chicago O'Hare Intl to Santa Ana J. Wayne/Orange Cnty.
Price to beat on a one-way flight from Chicago O'Hare Intl to Santa Ana J. Wayne/Orange Cnty.

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Santa Ana that are best for you.

Fly from

O'Hare Intl

Fly to

Santa Ana

Route

Depart

Return

Price

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Wed 2/11

7:48 pm-10:24 pm

Nonstop4h 36m

Santa Ana J. Wayne/Orange Cnty

Thu 2/19

2:22 pm-8:25 pm

Nonstop4h 03m

$269

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Wed 11/19

6:05 pm-11:19 am

1 stop19h 14m

Santa Ana J. Wayne/Orange Cnty

Fri 11/21

12:04 pm-12:10 am

1 stop10h 06m

$272

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Fri 12/5

7:50 pm-10:28 pm

Nonstop4h 38m

Santa Ana J. Wayne/Orange Cnty

Mon 12/8

12:15 pm-9:16 pm

1 stop7h 01m

$279

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Mon 11/17

6:00 am-11:16 am

1 stop7h 16m

Santa Ana J. Wayne/Orange Cnty

Thu 11/20

12:04 pm-12:10 am

1 stop10h 06m

$282

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Fri 1/9

7:30 am-6:25 pm

2 stops12h 55m

Santa Ana J. Wayne/Orange Cnty

Wed 1/14

9:51 am-11:53 pm

2 stops12h 02m

$296

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Mon 1/5

2:12 pm-8:22 pm

1 stop8h 10m

Santa Ana J. Wayne/Orange Cnty

Tue 1/6

4:47 pm-5:10 pm

2 stops22h 23m

$301

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Mon 12/15

7:50 pm-10:28 pm

Nonstop4h 38m

Santa Ana J. Wayne/Orange Cnty

Fri 12/19

6:45 am-1:04 pm

Nonstop4h 19m

$307

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Sun 11/23

5:00 am-9:02 am

1 stop6h 02m

Santa Ana J. Wayne/Orange Cnty

Thu 11/27

10:35 am-4:45 pm

Nonstop4h 10m

$314

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Wed 12/3

1:00 pm-8:15 pm

2 stops9h 15m

Santa Ana J. Wayne/Orange Cnty

Wed 12/10

1:10 pm-10:35 pm

1 stop7h 25m

$322

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Sat 11/22

7:00 am-11:19 am

1 stop6h 19m

Santa Ana J. Wayne/Orange Cnty

Tue 11/25

12:04 pm-12:10 am

1 stop10h 06m

$322

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 20 results
1
2

Compare providers for flights from O'Hare Intl to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Santa Ana in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
Kiwi.comPrice Accuracy3 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy3 starsTrust Score*2 stars
JustAirTicketPrice Accuracy-Trust Score*1 star
PricelinePrice Accuracy1 starTrust Score*3 stars
CheapfaremartPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Santa Ana, California flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Chicago O'Hare Intl Airport-Santa Ana, California flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Santa Ana, California flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Santa Ana, California flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from O'Hare Intl to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to Santa Ana

How far ahead should I book a flight from Chicago O'Hare Intl Airport to Santa Ana, California?

Use this chart to determine the optimal time to book a round-trip flight from O'Hare Intl to Santa Ana. Price data was last updated on October 31, 2025.

The best time to book flights from Chicago O'Hare Intl Airport to Santa Ana, California is 25 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Santa Ana, California?

Currently, September is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Santa Ana, California (average of $80). Flying from Chicago O'Hare Intl Airport to Santa Ana, California in December is currently the most expensive (average of $145). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to SNA?

Find hourly flight availability from O'Hare Intl to Santa Ana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 4, 2025.

It’s typically best to fly out from Chicago O'Hare Intl Airport to Santa Ana, California in the morning. Doing so could potentially save you 16% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Chicago O'Hare Intl Airport to Santa Ana, California?

Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to Santa Ana. Price data was last updated on November 2, 2025.

Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to Santa Ana, California flight should consider departing on Friday at noon when fares are most often at their lowest. Tuesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

The best insider tips for Chicago O'Hare Intl Airport to Santa Ana flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your Chicago O'Hare Intl Airport to Santa Ana trip
Airports
ORD

For a quick departure, use the free shuttle train between terminals at ORD, especially during busy weekday mornings.

Read more about ORDby Ramsey Qubein
SNA

At SNA, rideshare pickups are on the parking structure roof. Walk there before requesting your ride for a quicker exit.

Read more about SNAby Scott Laird
Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on ORD

Ramsey Qubein

Ramsey Qubein

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more
Scott Laird

Scott Laird

Expert on SNA

Scott Laird

Scott Laird

Originally from Anchorage, Alaska, Scott is a frequent contributor to Fodor’s Travel Guide, Conde Nast Traveler, TravelAge West, and TravelPulse. He holds a Bachelor of Science in Organizational Management from Alaska Pacific University and a Master of Science in Airline Management from Embry-Riddle Aeronautical University, and has worked in the airline and hotel industries and as a travel consultant.

Read more

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated November 4, 2025.
See what other customers who have flown with Alaska Airlines, United Airlines, and American Airlines from Chicago O'Hare Intl Airport to Santa Ana have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Overall

8.0

Comfort

7.8

Entertainment

7.0

Crew

8.5

Food

7.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Boarding

8.1

Overall

8.0

Comfort

7.8

Entertainment

7.0

Crew

8.5

Food

7.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Boarding

8.1

Overall

8.0

Comfort

7.8

Entertainment

7.0

Crew

8.5

Food

7.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Boarding

8.1

Overall

8.0

Comfort

7.8

Entertainment

7.0

Crew

8.5

Food

7.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Boarding

8.1

Overall

8.0

Comfort

7.8

Entertainment

7.0

Crew

8.5

Food

7.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Boarding

8.1

Overall

8.0

Comfort

7.8

Entertainment

7.0

Crew

8.5

Food

7.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Santa Ana from Chicago O'Hare Intl?

    Santa Ana J. Wayne/Orange Cnty (SNA), located 4.8 mi from the city center, is the airport you fly into when you book flights from Chicago O'Hare Intl to Santa Ana. 5 airlines have flights to J. Wayne/Orange Cnty from Chicago O'Hare Intl on a regular basis. Booking flights from Chicago O'Hare Intl to Santa Ana J. Wayne/Orange Cnty should not be difficult; the airport handles an average of 16 inbound flights from Chicago O'Hare Intl per day.

  • How long is the flight from Chicago O'Hare Intl Airport to Santa Ana, California?

    A quick flight from Chicago O'Hare Intl Airport to Santa Ana, California can take about 8h 02m. Frontier provides one of the quickest options available for as low as $279. There are 1721 mi between Chicago O'Hare Intl Airport and Santa Ana, California. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Chicago O'Hare Intl Airport to Santa Ana, California round-trip?

    Cheapflights users have booked flights from Chicago O'Hare Intl Airport to Santa Ana, California round-trip from $99. Other airlines that can offer you cheap pricing are Frontier, from $109, and American Airlines, from $269. You may be able to fly from Chicago O'Hare Intl Airport to Santa Ana, California for 73% less than the average price by searching for these airlines.

  • What are the most reliable airlines from Chicago O'Hare Intl Airport to Santa Ana, California?

    Before booking your flight to Santa Ana, California from Chicago O'Hare Intl Airport, check out the most reliable airlines to get you to your destination on time: Qatar Airways (85%), Aer Lingus (80%), Royal Jordanian( 77%).

  • What are the cheapest flights from Chicago O'Hare Intl Airport to Santa Ana, California?

    Looking at all options, your cheapest flight can be booked for $158. While the most popular route (Chicago O'Hare Intl - Santa Ana J. Wayne/Orange Cnty) can be booked for $138 on average, our data indicates $698 when flying from Chicago O'Hare Intl Airport to Santa Ana, California.

  • Can I find deals for flights from O'Hare Intl to Santa Ana that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Santa Ana.

  • Can I find deals for business class flights from O'Hare Intl to Santa Ana?

    Yes. Cheapflights offers flight deals from O'Hare Intl to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Santa Ana, California?

    Currently, September is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Santa Ana, California (average of $80). Flying from Chicago O'Hare Intl Airport to Santa Ana, California in December is currently the most expensive (average of $145). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from O'Hare Intl to Santa Ana

Discover the top 5 airlines that operate flights from O'Hare Intl to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$99Average$203FlexibilityNo cancel feeOn-time65%
FrontierCheapest$109Average$168FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$269Average$368FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$272Average$439FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$336Average$459FlexibilityNo cancel feeOn-time75%

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