$194+ Cheap flights from Roanoke to San Francisco (ROA - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — SFO
May 30 — Jun 61
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Roanoke to San FranciscoExplore the most affordable flight options available from Roanoke to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.
Explore the most affordable flight options available from Roanoke to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
ROA
- SFO
1 stop7h 12m
Delta
Wed 8/191:45 pm
SFO
- ROA
1 stop7h 05m
Delta
Deal found 4/27![Delta logo]()
$323
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:38 am
ROA
- SFO
2 stops9h 34m
American Airlines
Wed 8/268:00 am
SFO
- ROA
1 stop10h 10m
American Airlines
Deal found 4/29![American Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:50 pm
ROA
- SFO
1 stop9h 40m
United Airlines
Wed 9/210:55 pm
SFO
- ROA
1 stop7h 49m
United Airlines
Deal found 4/26![United Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:02 pm
ROA
- SFO
1 stop7h 47m
American Airlines
Wed 9/28:00 am
SFO
- ROA
1 stop10h 10m
American Airlines
Deal found 4/26![American Airlines logo]()
$343
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
ROA
- SFO
1 stop8h 48m
Delta
Wed 9/21:45 pm
SFO
- ROA
1 stop7h 05m
Delta
Deal found 4/26![Delta logo]()
$346
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/304:29 pm
ROA
- SFO
1 stop9h 20m
American Airlines
Wed 9/29:05 am
SFO
- ROA
2 stops10h 45m
American Airlines
Deal found 4/26![American Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:49 pm
ROA
- SFO
1 stop8h 21m
American Airlines
Sat 5/3012:18 am
SFO
- ROA
1 stop11h 06m
American Airlines
Deal found 4/29![American Airlines logo]()
$366
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:47 pm
ROA
- SFO
1 stop9h 45m
United Airlines
Mon 6/2911:05 pm
SFO
- ROA
1 stop7h 37m
United Airlines
Deal found 4/25![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:15 am
ROA
- SFO
1 stop9h 17m
United Airlines
Mon 6/110:38 pm
SFO
- ROA
1 stop8h 08m
United Airlines
Deal found 4/25![United Airlines logo]()
$392
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:38 am
ROA
- SFO
2 stops9h 34m
American Airlines
Wed 8/1911:00 am
SFO
- ROA
1 stop8h 50m
American Airlines
Deal found 4/28![American Airlines logo]()
$394
Best flights from Roanoke to San FranciscoDiscover carefully curated flight deals from Roanoke to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 30, 2026.
Discover carefully curated flight deals from Roanoke to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 30, 2026.
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
ROA
- SFO
1 stop7h 12m
Delta
Wed 8/191:45 pm
SFO
- ROA
1 stop7h 05m
Delta
Deal found 4/25![Delta logo]()
$323
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:47 pm
ROA
- SFO
1 stop9h 45m
United Airlines
Mon 6/2911:05 pm
SFO
- ROA
1 stop7h 37m
United Airlines
Deal found 4/25![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:38 am
ROA
- SFO
2 stops9h 34m
American Airlines
Wed 8/269:05 am
SFO
- ROA
2 stops10h 45m
American Airlines
Deal found 4/29![American Airlines logo]()
$396
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:59 pm
ROA
- SFO
1 stop8h 17m
United Airlines
Tue 5/1911:05 pm
SFO
- ROA
1 stop7h 52m
United Airlines
Deal found 4/25![United Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:29 pm
ROA
- SFO
1 stop9h 19m
American Airlines
Mon 8/106:00 am
SFO
- ROA
1 stop7h 59m
American Airlines
Deal found 4/30![American Airlines logo]()
$426
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:04 pm
ROA
- SFO
1 stop7h 45m
American Airlines
Sat 8/86:00 am
SFO
- ROA
1 stop7h 59m
American Airlines
Deal found 4/29![American Airlines logo]()
$426
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:05 pm
ROA
- SFO
1 stop8h 11m
United Airlines
Fri 10/3010:35 pm
SFO
- ROA
1 stop7h 48m
United Airlines
Deal found 4/27![United Airlines logo]()
$479
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:30 pm
ROA
- SFO
1 stop8h 16m
Delta
Sat 8/2210:30 pm
SFO
- ROA
1 stop9h 05m
Delta
Deal found 4/27![Delta logo]()
$574
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:45 am
ROA
- SFO
1 stop7h 39m
United Airlines
Sun 5/1711:56 pm
SFO
- ROA
1 stop6h 58m
United Airlines
Deal found 4/28![United Airlines logo]()
$559
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:49 pm
ROA
- SFO
2 stops10h 35m
American Airlines
Sun 5/315:00 am
SFO
- ROA
1 stop8h 04m
American Airlines
Deal found 4/29![American Airlines logo]()
$559
Last-minute flights from Roanoke to San FranciscoDiscover last-minute flight deals from Roanoke to San Francisco. Data last updated April 30, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to San Francisco. Data last updated April 30, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
ROA
- SFO
1 stop9h 33m
Delta
Wed 5/62:00 pm
SFO
- ROA
1 stop7h 25m
Delta
Deal found 4/27![Delta logo]()
$449
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:59 pm
ROA
- SFO
1 stop8h 17m
United Airlines
Tue 5/1911:05 pm
SFO
- ROA
1 stop7h 52m
United Airlines
Deal found 4/25![United Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:58 pm
ROA
- SFO
1 stop11h 21m
American Airlines
Sat 5/165:14 am
SFO
- ROA
2 stops10h 42m
American Airlines
Deal found 4/27![American Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:00 am
ROA
- SFO
1 stop10h 16m
American Airlines
Wed 8/196:00 am
SFO
- ROA
1 stop7h 59m
American Airlines
Deal found 4/29![American Airlines logo]()
$426
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:15 am
ROA
- SFO
1 stop7h 54m
United Airlines
Wed 6/39:30 pm
SFO
- ROA
1 stop9h 12m
United Airlines
Deal found 4/26![United Airlines logo]()
$433
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:49 pm
ROA
- SFO
1 stop8h 21m
American Airlines
Sat 5/3012:18 am
SFO
- ROA
1 stop11h 06m
American Airlines
Deal found 4/29![American Airlines logo]()
$366
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:15 am
ROA
- SFO
1 stop9h 17m
United Airlines
Mon 6/110:38 pm
SFO
- ROA
1 stop8h 08m
United Airlines
Deal found 4/25![United Airlines logo]()
$392
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
ROA
- SFO
1 stop8h 48m
Delta
Wed 9/21:45 pm
SFO
- ROA
1 stop7h 05m
Delta
Deal found 4/26![Delta logo]()
$346
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:29 pm
ROA
- SFO
1 stop9h 20m
American Airlines
Thu 6/412:59 am
SFO
- ROA
1 stop10h 25m
American Airlines
Deal found 4/29![American Airlines logo]()
$406
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/304:29 pm
ROA
- SFO
1 stop9h 20m
American Airlines
Wed 9/25:05 am
SFO
- ROA
1 stop8h 51m
American Airlines
Deal found 4/26![American Airlines logo]()
$323
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:00 am
ROA
- SFO
1 stop8h 53m
Delta
Tue 9/11:45 pm
SFO
- ROA
1 stop7h 05m
Delta
Deal found 4/26![Delta logo]()
$421
One-way flights from Roanoke to San FranciscoSearch for one-way flight options from Roanoke to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 30, 2026.
Search for one-way flight options from Roanoke to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:08 pm
ROA
- SFO
2 stops52h 49m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:51 am
ROA
- SFO
2 stops52h 00m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$268
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:00 am
ROA
- SFO
1 stop15h 00m
American Airlines
Deal found 4/25![American Airlines logo]()
$292
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:00 am
ROA
- SFO
1 stop15h 00m
American Airlines
Deal found 4/29![American Airlines logo]()
$306
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:00 am
ROA
- SFO
2 stops14h 48m
Delta
Deal found 4/26![Delta logo]()
$328
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:59 am
ROA
- SFO
1 stop14h 34m
American Airlines
Deal found 4/26![American Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:30 pm
ROA
- SFO
1 stop8h 16m
Delta
Deal found 4/29![Delta logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/610:46 am
ROA
- SFO
3 stops50h 41m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:00 am
ROA
- SFO
2 stops14h 26m
Delta
Deal found 4/26![Delta logo]()
$395
Find flight deals from Roanoke to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $323 (Delta) |
One-way from | $194 (Kiwi.com) |
Popular in | December |
Cheapest in | January |
Average price | $448 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Roanoke to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
RoanokeSan Francisco
ROA - SFO
ROASFO
Roanoke
Wed 8/12
6:00 am-10:12 am
1 stop7h 12m
San Francisco
Wed 8/19
1:45 pm-11:50 pm
1 stop7h 05m
$323
RoanokeSan Francisco
ROA - SFO
ROASFO
Roanoke
Fri 6/26
5:47 pm-12:32 am
1 stop9h 45m
San Francisco
Mon 6/29
11:05 pm-9:42 am
1 stop7h 37m
$369
RoanokeSan Francisco
ROA - SFO
ROASFO
Roanoke
Wed 8/19
6:38 am-1:12 pm
2 stops9h 34m
San Francisco
Wed 8/26
9:05 am-10:50 pm
2 stops10h 45m
$396
RoanokeSan Francisco
ROA - SFO
ROASFO
Roanoke
Mon 5/11
7:59 pm-1:16 am
1 stop8h 17m
San Francisco
Tue 5/19
11:05 pm-9:57 am
1 stop7h 52m
$409
RoanokeSan Francisco
ROA - SFO
ROASFO
Roanoke
Wed 8/5
5:29 pm-11:48 pm
1 stop9h 19m
San Francisco
Mon 8/10
6:00 am-4:59 pm
1 stop7h 59m
$426
RoanokeSan Francisco
ROA - SFO
ROASFO
Roanoke
Fri 5/29
6:04 pm-10:49 pm
1 stop7h 45m
San Francisco
Sat 8/8
6:00 am-4:59 pm
1 stop7h 59m
$426
RoanokeSan Francisco
ROA - SFO
ROASFO
Roanoke
Mon 10/19
8:05 pm-1:16 am
1 stop8h 11m
San Francisco
Fri 10/30
10:35 pm-9:23 am
1 stop7h 48m
$479
RoanokeSan Francisco
ROA - SFO
ROASFO
Roanoke
Wed 5/13
6:45 am-11:24 am
1 stop7h 39m
San Francisco
Sun 5/17
11:56 pm-9:54 am
1 stop6h 58m
$559
RoanokeSan Francisco
ROA - SFO
ROASFO
Roanoke
Thu 5/28
2:49 pm-10:24 pm
2 stops10h 35m
San Francisco
Sun 5/31
5:00 am-4:04 pm
1 stop8h 04m
$559
RoanokeSan Francisco
ROA - SFO
ROASFO
Roanoke
Thu 5/14
7:30 pm-12:46 am
1 stop8h 16m
San Francisco
Sat 8/22
10:30 pm-10:35 am
1 stop9h 05m
$574
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Roanoke to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to San Francisco in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Roanoke-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Roanoke-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Roanoke to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Roanoke with our price prediction graph.
ROA-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to San Francisco
How far ahead should I book a flight from Roanoke to San Francisco?
Booking 28 days in advance of your planned departure date is, on average, the best time to get cheap flights from Roanoke to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Roanoke to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Roanoke to San Francisco (average of $348). Flying from Roanoke to San Francisco in December is currently the most expensive (average of $609). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Roanoke to San Francisco?
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated April 30, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Roanoke to San Francisco have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Entertainment
7.8
Overall
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Comfort
7.9
Entertainment
7.8
Overall
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Comfort
7.9
Entertainment
7.8
Overall
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Comfort
7.9
Entertainment
7.8
Overall
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Related info for your journey
Find useful and relevant information for your journey from Roanoke to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
San Bruno
Watsonville
San Ramon
Emeryville
Vacaville
Roseville
San Carlos
Redwood City
Sunnyvale
Turlock
San Lorenzo
Davis
Manteca
Union City
Elk Grove
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Roanoke and San Francisco flights
Browse other Roanoke and San Francisco flight options. Last updated on April 30, 2026.
Other flights from Roanoke
Browse through other flights departing from Roanoke. Flights are based on user searches made on Cheapflights and were last updated on April 30, 2026.
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Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 30, 2026.
Top 3 airlines flying from Roanoke to San Francisco
Discover the top 3 airlines that operate flights from Roanoke to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$308 | Average$446 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$308 | Average$463 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$308 | Average$422 | FlexibilityNo cancel fee | On-timeN/A |