What are the cheapest airlines flying from Roanoke to San Francisco round-trip?

Cheapflights users have booked flights from Roanoke to San Francisco round-trip from $309. Other airlines that can offer you cheap pricing are American Airlines, from $314, and Delta, from $339. Users have found that United Airlines is 43% cheaper than the other options available to this destination.

What are the cheapest airlines to fly from Roanoke to San Francisco one-way?

The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $246. However, be on the lookout for offers from United Airlines and American Airlines, as they are both options that can get you from Roanoke to San Francisco for a low price.

What are the most popular airlines that fly from Roanoke to San Francisco?

Consider American Airlines, Delta or United Airlines when booking your flight. These represent the most popular airlines when flying from Roanoke to San Francisco.

What is the cheapest day to fly round-trip from Roanoke to San Francisco?

Travelers have found that booking a Tuesday departure is the best way to save up to 61% on the cost of booking your flights compared to booking on days of the week where this route is of high demand.

How far in advance should I book a flight from Roanoke to San Francisco?

To save up to 34% on this flight, we recommend booking at least 27 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Roanoke to San Francisco from $413 1-2 weeks out and tickets from $569 for flights departing within the next 72 hours.

What is the cheapest month to fly from Roanoke to San Francisco?

Due to multiple factors, expect to potentially pay more when booking in January. For low rates, August can be a great choice for travel to San Francisco. Flights to San Francisco from Roanoke in August are about $546 on average during August, but can be found for as low as $277.

Most accurate provider : When it comes to deals on Roanoke-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-San Francisco flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Roanoke-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Roanoke to San Francisco that include hotel bookings?

Yes. In addition to deals on Roanoke to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Roanoke to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to San Francisco.

Can I find deals for business class flights from Roanoke to San Francisco?

Yes. Cheapflights offers flight deals from Roanoke to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$246+ Flights from Roanoke to San Francisco - Compare & Save Big

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Roanoke to San Francisco are usually found in August or September, booked 89 days in advance, depart on a Wednesday or Saturday and return on a Tuesday

Cheap flight deals from Roanoke to San Francisco

Most accurate provider	FlightHub 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$309 (United Airlines)
One-way from	$246 (Delta)
Popular in	January
Cheapest in	August
Average price	$571

Provider with most accurate pricing for Roanoke-San Francisco flight deals.

Search Deals

Provider most trusted by Cheapflights users for Roanoke-San Francisco flights.

Search Deals

From Roanoke to San Francisco

Search Deals

One-way flight from Roanoke to San Francisco

Search Deals

Highest demand for flights based on searches. 16% potential increase in price ($108 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($24 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

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Find flight deals from Roanoke to San Francisco

Cheapest flights from Roanoke to San Francisco
Explore the most affordable flight options available from Roanoke to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2025.

Fri 8/157:50 pmROA - SFO

1 stop8h 07mUnited Airlines

Fri 8/2211:10 pmSFO - ROA

1 stop7h 56mUnited Airlines

Deal found 4/25

$309

Sat 8/3012:37 pmROA - SFO

2 stops10h 12mAmerican Airlines

Thu 9/116:27 amSFO - ROA

1 stop7h 36mAmerican Airlines

Deal found 4/24

$314

Fri 7/113:30 pmROA - SFO

1 stop10h 11mDelta

Sun 7/131:45 pmSFO - ROA

1 stop7h 06mDelta

Deal found 4/25

$339

Best flights from Roanoke to San Francisco
Discover carefully curated flight deals from Roanoke to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 25, 2025.

Fri 8/157:50 pmROA - SFO

1 stop8h 07mUnited Airlines

Fri 8/2211:10 pmSFO - ROA

1 stop7h 56mUnited Airlines

Deal found 4/25

$309

Sat 8/3012:37 pmROA - SFO

2 stops10h 12mAmerican Airlines

Thu 9/116:27 amSFO - ROA

1 stop7h 36mAmerican Airlines

Deal found 4/24

$314

Fri 7/113:30 pmROA - SFO

1 stop10h 11mDelta

Sun 7/131:45 pmSFO - ROA

1 stop7h 06mDelta

Deal found 4/25

$339

Last-minute flights from Roanoke to San Francisco
Discover last-minute flight deals from Roanoke to San Francisco. Data last updated April 25, 2025 and is based on user searches.

Thu 5/111:25 amROA - SFO

1 stop7h 55mDelta

Mon 5/56:00 amSFO - ROA

1 stop9h 15mDelta

Deal found 4/24

$459

Thu 5/12:55 pmROA - SFO

2 stops10h 44mAmerican Airlines

Mon 5/51:35 pmSFO - ROA

1 stop7h 13mAmerican Airlines

Deal found 4/24

$464

Thu 5/110:34 amROA - SFO

1 stop10h 04mUnited Airlines

Sun 5/412:10 amSFO - ROA

1 stop7h 14mUnited Airlines

Deal found 4/24

$559

Wed 5/144:22 pmROA - SFO

1 stop9h 39mAmerican Airlines

Wed 8/2011:00 amSFO - ROA

2 stops9h 40mAmerican Airlines

Deal found 4/25

$344

Fri 5/236:20 amROA - SFO

1 stop8h 10mUnited Airlines

Sat 5/3111:48 pmSFO - ROA

1 stop7h 26mUnited Airlines

Deal found 4/25

$494

One-way flights from Roanoke to San Francisco
Search for one-way flight options from Roanoke to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 25, 2025.

Tue 6/246:00 amROA - SFO

1 stop8h 43mDelta

Deal found 4/23

$246

Sat 6/287:50 pmROA - SFO

2 stops14h 49mUnited Airlines

Deal found 4/23

$265

Thu 6/269:40 pmROA - SFO

3 stops28h 13mMultiple Airlines

Deal found 4/23

$290

Thu 6/265:00 amROA - SFO

2 stops13h 57mAmerican Airlines

Deal found 4/23

$301

Cheapflights Fare Finder

Use the filters below to find and compare flights from Roanoke to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Fri 8/15

7:50 pm-12:57 am

1 stop8h 07m

San Francisco

Fri 8/22

11:10 pm-10:06 am

1 stop7h 56m

$309

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Sat 8/30

12:37 pm-7:49 pm

2 stops10h 12m

San Francisco

Thu 9/11

6:27 am-5:03 pm

1 stop7h 36m

$314

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Fri 7/11

3:30 pm-10:41 pm

1 stop10h 11m

San Francisco

Sun 7/13

1:45 pm-11:51 pm

1 stop7h 06m

$339

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Tue 6/24

6:00 am-11:43 am

1 stop8h 43m

$246

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Sat 6/28

7:50 pm-7:39 am

2 stops14h 49m

$265

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Thu 6/26

9:40 pm-10:53 pm

3 stops28h 13m

$290

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Thu 6/26

5:00 am-3:57 pm

2 stops13h 57m

$301

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Compare providers for flights from Roanoke to San Francisco

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to San Francisco in April.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*2 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Roanoke-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-San Francisco flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Roanoke-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Roanoke with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to San Francisco

How far ahead should I book a flight from Roanoke to San Francisco?

Booking 89 days in advance of your planned departure date is, on average, the best time to get cheap flights from Roanoke to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Roanoke to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Roanoke to San Francisco (average of $276). Flying from Roanoke to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to SFO?

Unlike at noon, when flights are generally more expensive, you can save up to 27% on flights from Roanoke to San Francisco by exploring options for tickets in the evening.

What is the cheapest day to fly from Roanoke to San Francisco?

Travelers seeking maximum savings on their Roanoke to San Francisco flight should consider departing on Saturday at noon when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in San Francisco by month

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Read reviews from past customers who have flown Delta, United Airlines and American Airlines from Roanoke to San Francisco. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

7,920 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines

7.4

Good

8,685 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What are the cheapest airlines flying from Roanoke to San Francisco round-trip?
Cheapflights users have booked flights from Roanoke to San Francisco round-trip from $309. Other airlines that can offer you cheap pricing are American Airlines, from $314, and Delta, from $339. Users have found that United Airlines is 43% cheaper than the other options available to this destination.
What are the cheapest airlines to fly from Roanoke to San Francisco one-way?
The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $246. However, be on the lookout for offers from United Airlines and American Airlines, as they are both options that can get you from Roanoke to San Francisco for a low price.
Can I find deals for flights from Roanoke to San Francisco that include hotel bookings?
Yes. In addition to deals on Roanoke to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Roanoke to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to San Francisco.
Can I find deals for business class flights from Roanoke to San Francisco?
Yes. Cheapflights offers flight deals from Roanoke to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Roanoke to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Roanoke to San Francisco (average of $276). Flying from Roanoke to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Manteca

Richmond

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Hollister

Milpitas

Antioch

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Hayward

Alameda

Sunnyvale

Campbell

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Top 3 airlines flying from Roanoke to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$282	Average$467	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$308	Average$557	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$318	Average$503	FlexibilityNo cancel fee	On-time69%

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$246+ Cheap flights from Roanoke to San Francisco (ROA - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Roanoke to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Roanoke to San Francisco are usually found in August or September, booked 89 days in advance, depart on a Wednesday or Saturday and return on a Tuesday

Cheap flight deals from Roanoke to San Francisco

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Roanoke to San Francisco

Cheapest flights from Roanoke to San FranciscoExplore the most affordable flight options available from Roanoke to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2025.

Explore the most affordable flight options available from Roanoke to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Roanoke to San Francisco that are best for you.

Compare providers for flights from Roanoke to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to San Francisco in April.

Best time to book a flight from Roanoke to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Roanoke with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to San Francisco

How far ahead should I book a flight from Roanoke to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Roanoke to San Francisco. Price data was last updated on April 18, 2025.

What is the cheapest month to book a flight from Roanoke to San Francisco?

What is the cheapest time of day to fly from ROA to SFO?

Find hourly flight availability from Roanoke to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 25, 2025.

What is the cheapest day to fly from Roanoke to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from Roanoke to San Francisco. Price data was last updated on December 16, 2024.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

Reviews of airlines servicing San Francisco

Read reviews from past customers who have flown Delta, United Airlines and American Airlines from Roanoke to San Francisco. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Roanoke to San Francisco round-trip?

What are the cheapest airlines to fly from Roanoke to San Francisco one-way?

Can I find deals for flights from Roanoke to San Francisco that include hotel bookings?

How can I find direct flights from Roanoke to San Francisco?

Can I find deals for business class flights from Roanoke to San Francisco?

What is the cheapest month to book a flight from Roanoke to San Francisco?

Traveling to a place near Roanoke?

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Alternative routes for Roanoke to San Francisco

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Top 3 airlines flying from Roanoke to San Francisco

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Cheapest flights from Roanoke to San Francisco
Explore the most affordable flight options available from Roanoke to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2025.