How long is the flight from Myrtle Beach to San Francisco?

A quick flight from Myrtle Beach to San Francisco can take about 9h 06m. American Airlines provides one of the quickest options available for as low as $447. Myrtle Beach and San Francisco are separated by a distance of 2431 mi. This flight may include one or multiple stops.

What are the cheapest airlines flying from Myrtle Beach to San Francisco round-trip?

Currently priced at $250, Delta will fly you from Myrtle Beach to San Francisco and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $312. You may be able to fly from Myrtle Beach to San Francisco for 53% less than the average price by searching for these airlines.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Most accurate provider : When it comes to deals on Myrtle Beach-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Myrtle Beach-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Myrtle Beach-San Francisco flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Myrtle Beach-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Myrtle Beach to San Francisco that include hotel bookings?

Yes. In addition to deals on Myrtle Beach to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Myrtle Beach to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to San Francisco.

Can I find deals for business class flights from Myrtle Beach to San Francisco?

Yes. Cheapflights offers flight deals from Myrtle Beach to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$136+ Flights from Myrtle Beach to San Francisco

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Cheap flight deals from Myrtle Beach to San Francisco

Best flights from Myrtle Beach to San Francisco
Discover carefully curated flight deals from Myrtle Beach to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

Wed 3/115:10 amMYR - SFO

1 stop10h 07mAmerican Airlines

Wed 3/1811:47 pmSFO - MYR

1 stop8h 41mAmerican Airlines

Deal found 12/26

$407

Wed 3/113:40 pmMYR - SFO

1 stop9h 25mSouthwest

Wed 3/186:25 amSFO - MYR

2 stops11h 45mSouthwest

Deal found 12/26

$412

Tue 3/241:01 pmMYR - SFO

1 stop9h 06mDelta

Tue 3/3111:35 pmSFO - MYR

1 stop7h 03mDelta

Deal found 12/26

$447

Sun 1/2510:30 amMYR - SFO

1 stop8h 15mSouthwest

Sun 2/16:25 amSFO - MYR

1 stop8h 35mSouthwest

Deal found 12/26

$447

Tue 3/241:58 pmMYR - SFO

1 stop9h 16mAmerican Airlines

Tue 3/317:00 pmSFO - MYR

2 stops10h 31mAmerican Airlines

Deal found 12/26

$452

Tue 6/92:10 pmMYR - SFO

2 stops11h 15mSouthwest

Tue 6/169:10 pmSFO - MYR

1 stop9h 40mSouthwest

Deal found 12/26

$452

Last-minute flights from Myrtle Beach to San Francisco
Discover last-minute flight deals from Myrtle Beach to San Francisco. Data last updated December 28, 2025 and is based on user searches.

Mon 1/54:00 pmMYR - SFO

1 stop10h 25mDelta

Sat 4/2510:55 pmSFO - MYR

1 stop10h 00mDelta

Deal found 12/27

$672

Mon 1/512:40 pmMYR - SFO

1 stop8h 40mSouthwest

Sat 4/256:15 amSFO - MYR

2 stops11h 30mSouthwest

Deal found 12/27

$717

Tue 1/61:25 pmMYR - SFO

1 stop9h 30mUnited Airlines

Tue 1/1310:50 pmSFO - MYR

1 stop10h 51mUnited Airlines

Deal found 12/27

$782

Wed 1/710:33 amMYR - SFO

1 stop10h 10mDelta

Wed 1/149:30 pmSFO - MYR

1 stop9h 16mDelta

Deal found 12/26

$732

Wed 1/75:44 pmMYR - SFO

1 stop18h 33mAmerican Airlines

Wed 1/149:10 amSFO - MYR

2 stops11h 47mAmerican Airlines

Deal found 12/27

$765

Wed 1/141:25 pmMYR - SFO

1 stop11h 12mUnited Airlines

Sat 1/1711:55 pmSFO - MYR

1 stop9h 46mUnited Airlines

Deal found 12/25

$603

Sun 1/2510:30 amMYR - SFO

1 stop8h 15mSouthwest

Sun 2/16:25 amSFO - MYR

1 stop8h 35mSouthwest

Deal found 12/26

$447

One-way flights from Myrtle Beach to San Francisco
Search for one-way flight options from Myrtle Beach to San Francisco. Find affordable one-way fares based on user searches. Data last updated December 28, 2025.

Mon 1/126:09 pmMYR - SFO

2 stops29h 37mMultiple Airlines

Deal found 12/26

$136

Sat 1/174:00 pmMYR - SFO

1 stop10h 25mDelta

Deal found 12/26

$154

Sat 1/178:00 amMYR - SFO

2 stops11h 01mAmerican Airlines

Deal found 12/26

$159

Sat 1/178:15 pmMYR - SFO

3 stops29h 52mMultiple Airlines

Deal found 12/26

$188

Sat 1/101:07 pmMYR - SFO

2 stops21h 56mMultiple Airlines

Deal found 12/26

$203

Wed 3/185:10 amMYR - SFO

1 stop10h 07mAmerican Airlines

Deal found 12/27

$224

Sat 1/106:00 amMYR - SFO

1 stop7h 36mDelta

Deal found 12/26

$284

Sun 1/49:54 amMYR - SFO

3 stops53h 00mMultiple Airlines

Deal found 12/27

$314

Mon 1/510:40 amMYR - SFO

2 stops52h 14mMultiple Airlines

Deal found 12/27

$316

Find flight deals from Myrtle Beach to San Francisco

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$407 (American Airlines)
One-way from	$136 (Kiwi.com)
Popular in	February
Cheapest in	April
Average price	$667

Provider with most accurate pricing for Myrtle Beach Intl-San Francisco flight deals.

Search Deals

Provider most trusted by Cheapflights users for Myrtle Beach Intl-San Francisco flights.

Search Deals

From Myrtle Beach Intl to San Francisco

Search Deals

One-way flight from Myrtle Beach Intl to San Francisco

Search Deals

Highest demand for flights based on searches. 26% potential increase in price ($191 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 13% potential price decrease ($64 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Myrtle Beach to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Wed 3/11

5:10 am-12:17 pm

1 stop10h 07m

San Francisco

Wed 3/18

11:47 pm-11:28 am

1 stop8h 41m

$407

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Wed 3/11

3:40 pm-10:05 pm

1 stop9h 25m

San Francisco

Wed 3/18

6:25 am-9:10 pm

2 stops11h 45m

$412

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Tue 3/24

1:01 pm-7:07 pm

1 stop9h 06m

San Francisco

Tue 3/31

11:35 pm-9:38 am

1 stop7h 03m

$447

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Sun 1/25

10:30 am-3:45 pm

1 stop8h 15m

San Francisco

Sun 2/1

6:25 am-6:00 pm

1 stop8h 35m

$447

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Tue 3/24

1:58 pm-8:14 pm

1 stop9h 16m

San Francisco

Tue 3/31

7:00 pm-8:31 am

2 stops10h 31m

$452

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Tue 6/9

2:10 pm-10:25 pm

2 stops11h 15m

San Francisco

Tue 6/16

9:10 pm-9:50 am

1 stop9h 40m

$452

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Mon 1/12

6:09 pm-8:46 pm

2 stops29h 37m

$136

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Sat 1/17

4:00 pm-11:25 pm

1 stop10h 25m

$154

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Sat 1/17

8:15 pm-11:07 pm

3 stops29h 52m

$188

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Sat 1/10

1:07 pm-8:03 am

2 stops21h 56m

$203

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/26

Showing 1-10 of 13 results

Compare providers for flights from Myrtle Beach to San Francisco

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to San Francisco in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Myrtle Beach-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Myrtle Beach-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Myrtle Beach-San Francisco flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Myrtle Beach-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Myrtle Beach with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to San Francisco

What is the cheapest month to book a flight from Myrtle Beach to San Francisco?

Currently, November is the cheapest month in which you can book a flight from Myrtle Beach to San Francisco (average of $160). Flying from Myrtle Beach to San Francisco in March is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SFO?

One of the essential ways to save on airfare from Myrtle Beach to San Francisco is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 7% on airfare.

Reviews of airlines servicing San Francisco

Peruse reviews from past customers who have flown with Delta and American Airlines from Myrtle Beach to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,019 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

7.9

Good

8,019 reviews

Delta

7.9

Good

8,019 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

11,072 reviews

Delta

7.9

Good

8,019 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

How long is the flight from Myrtle Beach to San Francisco?
A quick flight from Myrtle Beach to San Francisco can take about 9h 06m. American Airlines provides one of the quickest options available for as low as $447. Myrtle Beach and San Francisco are separated by a distance of 2431 mi. This flight may include one or multiple stops.
What are the cheapest airlines flying from Myrtle Beach to San Francisco round-trip?
Currently priced at $250, Delta will fly you from Myrtle Beach to San Francisco and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $312. You may be able to fly from Myrtle Beach to San Francisco for 53% less than the average price by searching for these airlines.
Can I find deals for flights from Myrtle Beach to San Francisco that include hotel bookings?
Yes. In addition to deals on Myrtle Beach to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Myrtle Beach to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to San Francisco.
Can I find deals for business class flights from Myrtle Beach to San Francisco?
Yes. Cheapflights offers flight deals from Myrtle Beach to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Myrtle Beach to San Francisco?
Currently, November is the cheapest month in which you can book a flight from Myrtle Beach to San Francisco (average of $160). Flying from Myrtle Beach to San Francisco in March is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Roseville

South San Francisco

Santa Cruz

Livermore

Turlock

Manteca

Watsonville

Redwood City

Sunnyvale

San Bruno

Daly City

Santa Clara

San Carlos

Vallejo

Hollister

San Ramon

Foster City

Union City

Davis

Emeryville

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Myrtle Beach to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$250	Average$406	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$312	Average$437	FlexibilityNo cancel fee	On-time71%

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$136+ Cheap flights from Myrtle Beach to San Francisco (MYR - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Myrtle Beach to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

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Cheap flight deals from Myrtle Beach to San Francisco

Best flights from Myrtle Beach to San FranciscoDiscover carefully curated flight deals from Myrtle Beach to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

Discover carefully curated flight deals from Myrtle Beach to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

Find flight deals from Myrtle Beach to San Francisco

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Myrtle Beach to San Francisco that are best for you.

Compare providers for flights from Myrtle Beach to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to San Francisco in December.

Best time to book a flight from Myrtle Beach to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Myrtle Beach with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to San Francisco

What is the cheapest month to book a flight from Myrtle Beach to San Francisco?

What is the cheapest time of day to fly from MYR to SFO?

Reviews of airlines servicing San Francisco

Peruse reviews from past customers who have flown with Delta and American Airlines from Myrtle Beach to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Myrtle Beach to San Francisco?

What are the cheapest airlines flying from Myrtle Beach to San Francisco round-trip?

Can I find deals for flights from Myrtle Beach to San Francisco that include hotel bookings?

How can I find direct flights from Myrtle Beach to San Francisco?

Can I find deals for business class flights from Myrtle Beach to San Francisco?

What is the cheapest month to book a flight from Myrtle Beach to San Francisco?

Traveling to a place near San Francisco?

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Alternative routes for Myrtle Beach to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Myrtle Beach to San Francisco

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Best flights from Myrtle Beach to San Francisco
Discover carefully curated flight deals from Myrtle Beach to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.