San Francisco

$313+ Cheap flights from Myrtle Beach to San Francisco (MYR - SFO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SFO
May 4 — May 111
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Myrtle Beach Intl to San Francisco are usually found in April or September, booked 8 days in advance, depart on a Thursday or Tuesday and return on a Wednesday

Cheap flight deals from Myrtle Beach to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$313
(American Airlines)

Popular in

July

Cheapest in

April

Average price

$368
Provider with most accurate pricing for Myrtle Beach Intl-San Francisco flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-San Francisco flights.
From Myrtle Beach Intl to San Francisco
Highest demand for flights based on searches. 12% potential increase in price ($65 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Average for round-trip flights in April 2025

Find flight deals from Myrtle Beach to San Francisco

Cheapest flights from Myrtle Beach to San Francisco
Explore the most affordable flight options available from Myrtle Beach to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/244:54 pmMYR - SFO
1 stop10h 28mAmerican Airlines
Tue 5/277:03 amSFO - MYR
1 stop7h 36mAmerican Airlines
Deal found 4/28$313
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/511:24 amMYR - SFO
1 stop9h 45mDelta
Sun 8/1010:40 pmSFO - MYR
1 stop8h 44mDelta
Deal found 4/28$370
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/247:15 amMYR - SFO
1 stop11h 00mSouthwest
Mon 7/289:00 pmSFO - MYR
1 stop10h 30mSouthwest
Deal found 4/27$407
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/281:45 pmMYR - SFO
2 stops30h 28mMultiple Airlines
Wed 6/46:14 pmSFO - MYR
2 stops19h 43mMultiple Airlines
Deal found 4/28$421
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/511:58 amMYR - SFO
1 stop10h 06mUnited Airlines
Mon 6/99:18 pmSFO - MYR
3 stops38h 17mUnited Airlines
Deal found 4/28$617
This KAYAK deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/241:40 pmMYR - SFO
3 stops48h 59mBreeze Airways
Mon 7/2812:29 pmSFO - MYR
3 stops44h 04mBreeze Airways
Deal found 4/27$967

Cheapflights Fare Finder

Customize your flight search to find flights from Myrtle Beach to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Myrtle Beach to San Francisco that are best for you.

Fly from

Myrtle Beach

Fly to

San Francisco

Route

Depart

Return

Price

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Sat 5/24

4:54 pm-12:22 am

1 stop10h 28m

San Francisco

Tue 5/27

7:03 am-5:39 pm

1 stop7h 36m

$313

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Tue 8/5

11:24 am-6:09 pm

1 stop9h 45m

San Francisco

Sun 8/10

10:40 pm-10:24 am

1 stop8h 44m

$370

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Thu 7/24

7:15 am-3:15 pm

1 stop11h 00m

San Francisco

Mon 7/28

9:00 pm-10:30 am

1 stop10h 30m

$407

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Wed 5/28

1:45 pm-5:13 pm

2 stops30h 28m

San Francisco

Wed 6/4

6:14 pm-4:57 pm

2 stops19h 43m

$421

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Thu 6/5

11:58 am-7:04 pm

1 stop10h 06m

San Francisco

Mon 6/9

9:18 pm-2:35 pm

3 stops38h 17m

$617

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Thu 7/24

1:40 pm-11:39 am

3 stops48h 59m

San Francisco

Mon 7/28

12:29 pm-11:33 am

3 stops44h 04m

$967

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Mon 5/5

3:15 pm-11:43 am

2 stops23h 28m

$359

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Compare providers for flights from Myrtle Beach to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to San Francisco in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to San Francisco

How far ahead should I book a flight from Myrtle Beach to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Myrtle Beach to San Francisco. Price data was last updated on April 25, 2025.

The best time to book flights from Myrtle Beach to San Francisco is 8 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Myrtle Beach to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to San Francisco (average of $276). Flying from Myrtle Beach to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SFO?

Find hourly flight availability from Myrtle Beach to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

One of the essential ways to save on airfare from Myrtle Beach to San Francisco is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight at noon could potentially save you up to 8% on airfare.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated April 29, 2025.

Boarding

8.3

Comfort

8.2

Crew

8.8

Entertainment

6.6

Food

6.7

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Boarding

8.3

Comfort

8.2

Crew

8.8

Entertainment

6.6

Food

6.7

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Boarding

8.3

Comfort

8.2

Crew

8.8

Entertainment

6.6

Food

6.7

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
8.0
Very good

Boarding

8.3

Comfort

8.2

Crew

8.8

Entertainment

6.6

Food

6.7

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Boarding

8.3

Comfort

8.2

Crew

8.8

Entertainment

6.6

Food

6.7

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Boarding

8.3

Comfort

8.2

Crew

8.8

Entertainment

6.6

Food

6.7

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines flying from Myrtle Beach to San Francisco round-trip?

    Currently priced at $313, American Airlines will fly you from Myrtle Beach to San Francisco and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and Southwest - these airlines can fly you to your destination from $370 and $407, respectively. You may be able to fly from Myrtle Beach to San Francisco for 30% less than the average price by searching for these airlines.

  • Can I find deals for flights from Myrtle Beach to San Francisco that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to San Francisco.

  • Can I find deals for business class flights from Myrtle Beach to San Francisco?

    Yes. Cheapflights offers flight deals from Myrtle Beach to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to San Francisco (average of $276). Flying from Myrtle Beach to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
Roseville
Mountain View
Santa Cruz
Turlock
Livermore
South San Francisco
Fairfield
Manteca
Richmond
Watsonville
Hollister
Milpitas
Antioch
Sausalito
Vallejo
Newark
Hayward
Alameda
Sunnyvale
Campbell

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Myrtle Beach to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Myrtle Beach to San Francisco

Discover the top 2 airlines that operate flights from Myrtle Beach to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$250Average$426FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$306Average$468FlexibilityNo cancel feeOn-time71%

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