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$137+ Cheap flights from Louisville to San Francisco (SDF - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — SFO
Apr 9 — Apr 161
Thu 4/9
Thu 4/16
1 adult, Economy
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Find cheap flights from Louisville to San Francisco with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheapflights Tip: The best prices from Louisville Intl to San Francisco are usually found in September or November, booked 35 days in advance, depart on a Tuesday or Thursday and return on a Wednesday

Cheap flight deals from Louisville to San Francisco

Cheapest flights from Louisville to San Francisco
Explore the most affordable flight options available from Louisville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.

This Breeze Airways deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:31 am
SDF
-
SFO
Nonstop5h 02m
Breeze Airways
Mon 8/2412:18 pm
SFO
-
SDF
Nonstop4h 30m
Breeze Airways
Deal found 3/6$228
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:31 am
SDF
-
SFO
Nonstop5h 02m
Breeze Airways
Mon 8/2412:18 pm
SFO
-
SDF
Nonstop4h 30m
Breeze Airways
Deal found 3/10$256
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/109:31 am
SDF
-
SFO
Nonstop5h 02m
Breeze Airways
Mon 8/2412:18 pm
SFO
-
SDF
Nonstop4h 30m
Breeze Airways
Deal found 3/10$277
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/199:21 am
SDF
-
SFO
1 stop12h 49m
Multiple Airlines
Tue 8/258:20 pm
SFO
-
SDF
1 stop20h 06m
Multiple Airlines
Deal found 3/8$284
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/59:21 am
SDF
-
SFO
1 stop12h 49m
Multiple Airlines
Mon 8/2412:18 pm
SFO
-
SDF
Nonstop4h 30m
Multiple Airlines
Deal found 3/10$296
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:21 am
SDF
-
SFO
1 stop12h 49m
Multiple Airlines
Tue 8/258:20 pm
SFO
-
SDF
1 stop20h 06m
Multiple Airlines
Deal found 3/8$302
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:21 am
SDF
-
SFO
1 stop15h 13m
Multiple Airlines
Tue 5/125:49 pm
SFO
-
SDF
1 stop22h 37m
Multiple Airlines
Deal found 3/10$308
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:31 am
SDF
-
SFO
Nonstop5h 02m
Multiple Airlines
Tue 8/188:20 pm
SFO
-
SDF
1 stop20h 06m
Multiple Airlines
Deal found 3/10$309
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:48 pm
SDF
-
SFO
2 stops24h 46m
Multiple Airlines
Tue 5/55:49 pm
SFO
-
SDF
1 stop22h 37m
Multiple Airlines
Deal found 3/8$310
This Booking.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/39:31 am
SDF
-
SFO
Nonstop5h 02m
Breeze Airways
Fri 7/1012:18 pm
SFO
-
SDF
Nonstop4h 30m
Breeze Airways
Deal found 3/7$312

Find flight deals from Louisville to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$228
(Breeze Airways)

One-way from

$137
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$486

Good round-trip deal

$278 or less

Good one-way deal

$339 or less
Provider with most accurate pricing for Louisville Intl-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-San Francisco flights.
Search Deals
From Louisville Intl to San Francisco
Search Deals
One-way flight from Louisville Intl to San Francisco
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($60 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Louisville Intl to San Francisco.
Search Deals
Price to beat on a one-way flight from Louisville Intl to San Francisco.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Louisville to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Thu 5/14

8:10 pm-12:20 am

1 stop7h 10m

San Francisco

Wed 5/20

8:55 am-6:35 pm

1 stop6h 40m

$369

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Thu 4/9

8:10 pm-12:20 am

1 stop7h 10m

San Francisco

Mon 4/13

11:25 pm-9:50 am

1 stop7h 25m

$379

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Mon 6/1

3:40 pm-11:05 pm

2 stops10h 25m

San Francisco

Mon 6/8

11:40 pm-10:05 am

1 stop7h 25m

$384

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Thu 4/30

5:25 pm-12:10 am

2 stops9h 45m

San Francisco

Tue 5/5

10:40 pm-12:40 pm

2 stops11h 00m

$389

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Thu 4/16

12:20 pm-10:10 pm

2 stops12h 50m

San Francisco

Mon 4/20

8:50 am-9:00 pm

2 stops9h 10m

$395
Quickest round-trip

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Mon 6/1

9:31 am-11:33 am

Nonstop5h 02m

San Francisco

Mon 6/8

12:18 pm-7:48 pm

Nonstop4h 30m

$418

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Thu 5/21

5:25 pm-12:10 am

2 stops9h 45m

San Francisco

Thu 6/4

6:05 am-5:25 pm

2 stops8h 20m

$428

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Fri 5/22

8:10 pm-12:20 am

1 stop7h 10m

San Francisco

Mon 5/25

11:25 pm-9:50 am

1 stop7h 25m

$437

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Thu 5/21

5:25 pm-12:10 am

2 stops9h 45m

San Francisco

Tue 5/26

7:20 am-8:35 pm

2 stops10h 15m

$448

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Tue 4/14

3:30 pm-10:30 pm

1 stop10h 00m

San Francisco

Wed 4/15

2:10 pm-11:59 pm

1 stop6h 49m

$449

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/9

Showing 1-10 of 22 resultsSorted by cheapest first
1
2
3

Compare providers for flights from Louisville to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to San Francisco in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
CheapOairPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Louisville-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Louisville-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Louisville to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to San Francisco

How far ahead should I book a flight from Louisville to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Louisville to San Francisco. Price data was last updated on March 6, 2026.

The best time to book flights from Louisville to San Francisco is 35 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Louisville to San Francisco?

Currently, September is the cheapest month in which you can book a flight from Louisville to San Francisco (average of $131). Flying from Louisville to San Francisco in March is currently the most expensive (average of $257). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated March 10, 2026.
Peruse reviews from past customers who have flown with Breeze Airways,Southwest, andDelta from Louisville to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
271 reviews

Entertainment

6.6

Crew

8.7

Food

6.6

Boarding

8.3

Overall

8.1

Comfort

8.2

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Breeze Airways
8.1
Very good
271 reviews
Breeze Airways
8.1
Very good
271 reviews

Entertainment

6.6

Crew

8.7

Food

6.6

Boarding

8.3

Overall

8.1

Comfort

8.2

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Southwest
8.0
Very good
4,317 reviews
Breeze Airways
8.1
Very good
271 reviews

Entertainment

6.6

Crew

8.7

Food

6.6

Boarding

8.3

Overall

8.1

Comfort

8.2

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Delta
7.9
Good
8,276 reviews
Breeze Airways
8.1
Very good
271 reviews

Entertainment

6.6

Crew

8.7

Food

6.6

Boarding

8.3

Overall

8.1

Comfort

8.2

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
United Airlines
7.4
Good
9,409 reviews
Breeze Airways
8.1
Very good
271 reviews

Entertainment

6.6

Crew

8.7

Food

6.6

Boarding

8.3

Overall

8.1

Comfort

8.2

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
American Airlines
7.1
Good
11,415 reviews
Breeze Airways
8.1
Very good
271 reviews

Entertainment

6.6

Crew

8.7

Food

6.6

Boarding

8.3

Overall

8.1

Comfort

8.2

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.

Related info for your journey

Find useful and relevant information for your journey from Louisville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Louisville to San Francisco flight route?

    This flight path from Louisville Intl to San Francisco was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Louisville to San Francisco?

    A quick flight from Louisville to San Francisco can take about 7h 10m. Southwest provides one of the quickest options available for as low as $369. The distance from Louisville to San Francisco is about 1984 mi.

  • What are the cheapest airlines flying from Louisville to San Francisco round-trip?

    According to our current data, Breeze Airways ($139), Delta ($142), and Southwest ($254) offers the cheapest pricing from Louisville to San Francisco. Breeze Airways is currently priced 63% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Louisville to San Francisco one-way?

    For one-way options, check prices for Breeze Airways. According to our data, you can fly for as low as $108. Users have also found prices from $135 and $163 on American Airlines and United Airlines, respectively.

  • What are the cheapest flights from Louisville to San Francisco?

    Looking for the cheapest flight from Louisville to San Francisco? While on average our users pay $323, our data indicates the cheapest price to be $149. The most popular route (Louisville Intl - San Francisco), is priced around $237.

  • Can I find deals for flights from Louisville to San Francisco that include hotel bookings?

    Yes. In addition to deals on Louisville to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to San Francisco.

  • Can I find deals for business class flights from Louisville to San Francisco?

    Yes. Cheapflights offers flight deals from Louisville to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to San Francisco?

    Currently, September is the cheapest month in which you can book a flight from Louisville to San Francisco (average of $131). Flying from Louisville to San Francisco in March is currently the most expensive (average of $257). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Clara
Santa Cruz
Livermore
Roseville
Watsonville
San Bruno
Sunnyvale
Vacaville
Turlock
San Carlos
San Ramon
Redwood City
Daly City
Rancho Cordova
San Lorenzo
Davis
Hollister
Manteca
Union City

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Top 5 airlines flying from Louisville to San Francisco

Discover the top 5 airlines that operate flights from Louisville to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$139Average$278FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$142Average$428FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$254Average$466FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$262Average$406FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$283Average$513FlexibilityNo cancel feeOn-time69%

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