$544+ Cheap flights from La Crosse to San Francisco (LSE - SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — SFO
Jan 3 — Jan 101
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from La Crosse to San Francisco
Cheapest flights from La Crosse to San FranciscoExplore the most affordable flight options available from La Crosse to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.
Explore the most affordable flight options available from La Crosse to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:00 amLSE - SFO
1 stop10h 08mAmerican Airlines
Sat 12/207:07 pmSFO - LSE
2 stops12h 32mAmerican Airlines
Deal found 12/2![American Airlines logo]()
$595
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:00 amLSE - SFO
1 stop9h 10mAmerican Airlines
Sun 12/71:11 pmSFO - LSE
1 stop8h 41mAmerican Airlines
Deal found 12/2![American Airlines logo]()
$620
This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:00 amLSE - SFO
1 stop9h 10mAmerican Airlines
Sun 12/2110:49 pmSFO - LSE
1 stop8h 50mAmerican Airlines
Deal found 12/4![American Airlines logo]()
$639
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:00 amLSE - SFO
2 stops11h 58mAmerican Airlines
Fri 1/210:49 pmSFO - LSE
1 stop8h 53mAmerican Airlines
Deal found 12/2![American Airlines logo]()
$1,048
Find flight deals from La Crosse to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 4, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $544 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from La Crosse to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from La Crosse to San Francisco that are best for you.
Fly from
La Crosse
Fly to
San Francisco
Route
Depart
Return
Price
La CrosseSan Francisco
LSE - SFO
LSESFO
La Crosse
Sat 2/14
6:00 am-1:03 pm
1 stop9h 03m
San Francisco
Wed 2/18
1:47 pm-11:22 pm
1 stop7h 35m
$544
La CrosseSan Francisco
LSE - SFO
LSESFO
La Crosse
Tue 12/16
6:00 am-2:08 pm
1 stop10h 08m
San Francisco
Sat 12/20
7:07 pm-9:39 am
2 stops12h 32m
$595
La CrosseSan Francisco
LSE - SFO
LSESFO
La Crosse
Thu 12/18
6:00 am-3:58 pm
2 stops11h 58m
San Francisco
Mon 12/22
6:50 pm-9:39 am
2 stops12h 49m
$631
La CrosseSan Francisco
LSE - SFO
LSESFO
La Crosse
Fri 3/13
10:09 am-8:56 pm
2 stops12h 47m
San Francisco
Mon 3/16
7:00 pm-9:24 am
2 stops12h 24m
$631
La CrosseSan Francisco
LSE - SFO
LSESFO
La Crosse
Mon 12/15
9:46 am-5:20 pm
2 stops9h 34m
San Francisco
Sun 12/21
6:50 pm-9:39 am
2 stops12h 49m
$631
Compare providers for flights from La Crosse to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from La Crosse to San Francisco in December.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star |
- Most accurate provider: When it comes to deals on La Crosse-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on La Crosse-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from La Crosse-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on La Crosse-San Francisco flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for La Crosse-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from La Crosse to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated December 4, 2025.
Read through reviews of airlines operating flights from La Crosse to San Francisco, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Overall
7.2
Boarding
7.5
Crew
8.0
Food
6.5
Entertainment
6.9
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2024
LHR - SAN
Comfort
7.2
Overall
7.2
Boarding
7.5
Crew
8.0
Food
6.5
Entertainment
6.9
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2024
LHR - SAN
Related info for your journey
Find useful and relevant information for your journey from La Crosse to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsRoseville
South San Francisco
Santa Cruz
Livermore
Turlock
Manteca
Watsonville
Sunnyvale
Santa Clara
San Bruno
Daly City
Redwood City
Vallejo
Hollister
Milpitas
Foster City
Union City
Davis
San Ramon
Burlingame
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Alternative routes for La Crosse to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Top airline flying from La Crosse to San Francisco
Discover the top airline that operate flights from La Crosse to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$454 | Average$539 | FlexibilityNo cancel fee | On-time71% |