$484+ Cheap flights from La Crosse to San Francisco (LSE - SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/9. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — SFO
Jan 11 — Jan 181
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from La Crosse to San Francisco
Cheapest flights from La Crosse to San FranciscoExplore the most affordable flight options available from La Crosse to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.
Explore the most affordable flight options available from La Crosse to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:00 amLSE - SFO
1 stop9h 10mAmerican Airlines
Sun 12/216:50 pmSFO - LSE
2 stops12h 49mAmerican Airlines
Deal found 12/10![American Airlines logo]()
$626
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 amLSE - SFO
2 stops11h 06mAmerican Airlines
Sun 12/2810:49 pmSFO - LSE
1 stop8h 50mAmerican Airlines
Deal found 12/8![American Airlines logo]()
$842
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amLSE - SFO
2 stops11h 06mAmerican Airlines
Mon 12/2910:49 pmSFO - LSE
1 stop8h 50mAmerican Airlines
Deal found 12/10![American Airlines logo]()
$880
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:06 pmLSE - SFO
2 stops15h 46mAmerican Airlines
Fri 1/210:49 pmSFO - LSE
1 stop8h 53mAmerican Airlines
Deal found 12/9![American Airlines logo]()
$897
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:00 amLSE - SFO
1 stop7h 06mAmerican Airlines
Tue 12/3010:49 pmSFO - LSE
1 stop8h 50mAmerican Airlines
Deal found 12/11![American Airlines logo]()
$918
Find flight deals from La Crosse to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $484 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from La Crosse to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from La Crosse to San Francisco that are best for you.
Fly from
La Crosse
Fly to
San Francisco
Route
Depart
Return
Price
La CrosseSan Francisco
LSE - SFO
LSESFO
La Crosse
Fri 1/9
5:08 pm-10:34 pm
1 stop7h 26m
San Francisco
Tue 1/13
6:00 am-4:16 pm
1 stop8h 16m
$484
La CrosseSan Francisco
LSE - SFO
LSESFO
La Crosse
Thu 3/12
6:28 pm-11:45 pm
1 stop7h 17m
San Francisco
Mon 3/23
11:47 pm-9:24 am
1 stop7h 37m
$567
La CrosseSan Francisco
LSE - SFO
LSESFO
La Crosse
Wed 3/11
6:28 pm-11:45 pm
1 stop7h 17m
San Francisco
Sun 3/22
11:47 pm-10:08 am
1 stop8h 21m
$587
La CrosseSan Francisco
LSE - SFO
LSESFO
La Crosse
Thu 3/12
6:28 pm-11:45 pm
1 stop7h 17m
San Francisco
Sun 3/22
11:47 pm-10:08 am
1 stop8h 21m
$617
La CrosseSan Francisco
LSE - SFO
LSESFO
La Crosse
Mon 12/29
6:00 am-5:04 pm
2 stops13h 04m
$753
Compare providers for flights from La Crosse to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from La Crosse to San Francisco in December.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star |
- Most accurate provider: When it comes to deals on La Crosse-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on La Crosse-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from La Crosse-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on La Crosse-San Francisco flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for La Crosse-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from La Crosse to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated December 12, 2025.
Read through reviews of airlines operating flights from La Crosse to San Francisco, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.9
Food
6.5
Boarding
7.5
Comfort
7.2
Crew
8.0
Overall
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2024
LHR - SAN
Entertainment
6.9
Food
6.5
Boarding
7.5
Comfort
7.2
Crew
8.0
Overall
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2024
LHR - SAN
Related info for your journey
Find useful and relevant information for your journey from La Crosse to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsRoseville
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Alternative routes for La Crosse to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Top airline flying from La Crosse to San Francisco
Discover the top airline that operate flights from La Crosse to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$454 | Average$539 | FlexibilityNo cancel fee | On-time71% |